MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Rolitetracycline | Rolitetracycline, a derivative of tetracycline, is a broad-spectrum antibiotic [1] [2]. Rolitetracyclin has a role as a protein synthesis inhibitor, an antiprotozoal agent and a proagent [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 751-97-3. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-18257. |  |
| Rolofylline | Rolofylline (KW-3902) is a potent, selective adenosine A1 receptor antagonist that is under development for the treatment of patients with acute congestive heart failure and renal impairment. Rolofylline is metabolized primarily to the pharmacologically active M1-trans and M1-cis metabolites by cytochrome P450 ( CYP 450 ) [1]. Rolofylline is alleviating the presynaptic dysfunction and restores neuronal activity as well as dendritic spine levels in vitro, is an interesting candidate to combat the hypometabolism and neuronal dysfunction associated with Tau-induced neurodegenerative diseases [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KW-3902. CAS No. 136199-02-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10965. | |
| Roluperidone | Roluperidone (CYR-101) is a novel cyclic amide derivative that has high equipotent affinities for 5-HT 2A and sigma-2 receptors ( K i of 7.53 nM and 8.19 nM for 5-HT 2A and sigma-2, respectively). Uses: Scientific research. Group: Signaling pathways. Alternative Names: CYR-101; MIN-101; MT-210. CAS No. 359625-79-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19469. | |
| Romidepsin | Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC 50 s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively [1]. Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FK 228; FR 901228; NSC 630176. CAS No. 128517-07-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15149. | |
| Romifidine | Romifidine is an α 2 adrenergic receptor agonist. Romifidine shows sedation effects in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 65896-16-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-119456. | |
| Romiplostim | Romiplostim is a fusion protein analogue of TPO (thrombopoietin protein) Fc peptide, and is a peptide-body molecule. Romiplostim increases platelet production by activating the thrombopoietin receptor TPO receptor. The peptidosome molecule has two identical single-stranded subunits, each consisting of 269 amino acid residues [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2626841-92-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990685. | |
| Romlusevimab | Romlusevimab (BRII-198) is a neutralizing recombinant human IgG1 monoclonal antibody against the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BRII-198. CAS No. 2509447-08-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99889. | |
| Romosozumab | Romosozumab is a humanized monoclonal anti-sclerostin antibody , it promotes bone formation and inhibits bone resorption by inhibiting sclerostin. Romosozumab can be used for the research of osteoporosis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 909395-70-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9982. | |
| Ronacaleret hydrochloride | Ronacaleret hydrochloride (SB 751689A) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret hydrochloride (SB 751689A) is used for the study of postmenopausal osteoporosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB 751689A. CAS No. 702686-96-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-15104. | |
| Ronidazole | Ronidazole is a potent and orally active antiprotozoal and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus in cats models. Ronidazole can be used the research of forhistomoniasis and swine dysentery [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7681-76-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0565. | |
| Ronidazole (Standard) | Ronidazole (Standard) is the analytical standard of Ronidazole. This product is intended for research and analytical applications. Ronidazole is a potent and orally active antiprotozoal and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus in cats models. Ronidazole can be used the research of forhistomoniasis and swine dysentery [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7681-76-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0565R. | |
| Rontalizumab | Rontalizumab is a humanized IgG1 monoclonal antibody targets IFN-&alpha. Rontalizumab can be used for the research of systemic lupus erythematosus[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RhuMab IFNalpha; Anti-Human IFN alpha Recombinant Antibody. CAS No. 948570-30-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99267. | |
| Ropeginterferon alfa-2b | Ropeginterferon alfa-2b (Ropeginterferon alfa-2b-njft) is a monopegylated IFN-α that can be used for the research of myeloproliferative neoplasms [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Ropeginterferon alfa-2b-njft; PEG-proline-interferon alpha-2b. CAS No. 1335098-50-4. Pack Sizes: 250 μg. Product ID: HY-P99348. | |
| Ropidoxuridine | Ropidoxuridine (IPdR) is a novel orally available, halogenated thymidine analog and is a potential radiosensitizer for use in human tumors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IPdR. CAS No. 93265-81-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13742. | |
| Ropinirole hydrochloride | Ropinirole (SKF 101468) hydrochloride is an orally active, potent D 3 /D 2 receptor agonist with a K i of 29 nM for D 2 receptor. Ropinirole hydrochloride has pEC 50 s of 7.4, 8.4 and 6.8 for hD 2 , hD 3 and hD 4 receptors, respectively. Ropinirole hydrochloride has no affinity for the D 1 receptors. Ropinirole hydrochloride has the potential for Parkinson's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF 101468 hydrochloride. CAS No. 91374-20-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-B0623A. | |
| Ropivacaine | Ropivacain is a potent sodium channel blocker. Ropivacain blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese [1] [2]. Ropivacaine is also an inhibitor of K 2P (two-pore domain potassium channel) TREK-1 with an IC 50 of 402.7 μM in COS-7 cell's membrane [3]. Ropivacaine is used for the research of neuropathic pain management [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 84057-95-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0563. | |
| Ropivacaine hydrochloride | Ropivacaine hydrochloride is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese [1] [2]. Ropivacaine is also an inhibitor of K 2P (two-pore domain potassium channel) TREK-1 with an IC 50 of 402.7 μM in COS-7 cell's membrane [3]. Ropivacaine is widely used for neuropathic pain management in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 98717-15-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0563B. | |
| Ropivacaine hydrochloride monohydrate | Ropivacaine hydrochloride monohydrate is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese [1] [2]. Ropivacaine is also an inhibitor of K 2P (two-pore domain potassium channel) TREK-1 with an IC 50 of 402.7 μM in COS-7 cell's membrane [3]. Ropivacaine is widely used for regional anesthesia and neuropathic pain management in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 132112-35-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0563A. | |
| Ropivacaine mesylate | Ropivacaine mesylate is a long-acting amide local anaesthetic agent for a spinal block and effectively blocks neuropathic pain. Ropivacaine blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibressup>[1] [2]. Ropivacaine is also an inhibitor of K 2P (two-pore domain potassium channel) TREK-1 with an IC 50 of 402.7 μM in COS-7 cell's membrane [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 854056-07-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0563C. | |
| Roquefortine C | Roquefortine C, a fungal cyclopeptide isolated from Penicillium roquefortii , activates P-gp and also inhibits P450-3A and other haemoproteins. Roquefortine C has bacteriostatic activities against Gram-positive bacteria [1]. Uses: Scientific research. Group: Natural products. CAS No. 58735-64-1. Pack Sizes: 500 μg; 1 mg. Product ID: HY-N6748. | |
| Roquinimex | Roquinimex (Linomide; PNU212616; ABR212616) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Linomide; FCF89; ABR212616. CAS No. 84088-42-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13743. | |
| RORγt agonist 3 | RORγt agonist 3 is a potent agonist of RORγt. RORγt agonist 3 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 3 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136326A1, compound 23) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2664106-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-142938. | |
| Rosavin | Rosavin, an orally bioactive phenylpropanoid from Rhodiola rosea L. (RRL) , is an adaptogen that enhances the bodys response to environmental stress. Rosavin significantly influences bone tissue metabolism by inhibiting osteoclastogenesis and promoting osteoblast differentiation, also impacts various diseases, demonstrating antidepressant, adaptogenic, and anxiolytic effects in mouse models. Additionally, Rosavin improves survival, reducing intestinal damage in irradiated rats and Ischemia-reperfusion(I/R)-induced cerebral injury in vivo by regulating inflammation and oxidative stress, making it a promising candidate for research in radiation-induced intestinal injury, I/R-induced cerebral injury and osteoporosis [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 84954-92-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0507. | |
| Rose Bengal sodium | Rose Bengal sodium, a synthetic fluorescein derivative, is a deep red dye primarily composed of 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. It is widely used as an ophthalmic diagnostic agent to detect dry or damaged cells on the ocular surface. Rose Bengal sodium exhibits antitumor activity and can inhibit Friend Leukemia Virus ( FLV ) infection through photodynamic action. Additionally, Rose Bengal sodium can inhibit Aβ aggregation through light irradiation. Rose Bengal sodium holds potential for use in cancer, viral infections, and neurodegenerative disease research [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 632-69-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-D0214. | |
| Rosiglitazone | Rosiglitazone (BRL 49653) is an orally active selective PPARγ agonist ( EC 50 : 60 nM, K d : 40 nM). Rosiglitazone is an TRPC5 activator ( EC 50 : 30 μM) and TRPM3 inhibitor. Rosiglitazone can be used in the research of obesity and diabetes, senescence, ovarian cancer [1] [2] [4] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL 49653. CAS No. 122320-73-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-17386. | |
| Rosiglitazone hydrochloride | Rosiglitazone (BRL 49653) hydrochloride is an orally active selective PPARγ agonist ( EC 50 : 60 nM, K d : 40 nM). Rosiglitazone hydrochloride is a TRPC5 activator ( EC 50 : 30 μM) and TRPM3 inhibitor. Rosiglitazone hydrochloride can be used in the research of obesity and diabetes, senescence, ovarian cancer [1] [2] [4] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL 49653 hydrochloride. CAS No. 302543-62-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-17386A. | |
| Rosiglitazone maleate | Rosiglitazone maleate (BRL 49653C) is a potent and selective activator of PPARγ , with EC 50 s of 30 nM, 100 nM and 60 nM for PPARγ1 , PPARγ2 , and PPARγ , respectively, and a K d of appr 40 nM for PPARγ ; Rosiglitazone maleate is also an modulator of TRP channels , inhibits TRP melastatin 2 (TRPM2), TRPM3 and activates TRP canonical 5 (TRPC5). Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL 49653C. CAS No. 155141-29-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-14600. | |
| Rosin | Rosin is isolated from pine wood or pine stumps, Rosin is a frequent contact allergen which induces allergic contact dermatitis [1]. Uses: Scientific research. Group: Natural products. CAS No. 85026-55-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0508. | |
| ROS kinases-IN-1 | ROS kinases-IN-1 (pag 98) is a ROS tyrosine kinase inhibitor with IC 50 value of 1.22 μM. ROS kinases-IN-1 shows anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 370096-57-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148228. | |
| Rosmanol | Rosmanol could inhibit the oxidation of low density lipoprotein (LPL) and significantly inhibit lipopolysaccharide induced iNOS and COX-2 expression, with anti-inflammatory effect. Uses: Scientific research. Group: Natural products. CAS No. 80225-53-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N5015. | |
| Rosmarinic acid | Rosmarinic acid is a widespread phenolic ester compound in the plants. Rosmarinic acid inhibits MAO-A , MAO-B and COMT enzymes with IC 50 s of 50.1, 184.6 and 26.7 μM, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: Labiatenic acid. CAS No. 20283-92-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0529. | |
| Rosmarinic acid (Standard) | Rosmarinic acid (Standard) is the analytical standard of Rosmarinic acid. This product is intended for research and analytical applications. Rosmarinic acid is a widespread phenolic ester compound in the plants. Rosmarinic acid inhibits MAO-A, MAO-B and COMT enzymes with IC 50 s of 50.1, 184.6 and 26.7 μM, respectively. Uses: Scientific research. Group: Natural products. CAS No. 20283-92-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0529R. | |
| Rosnilimab | Rosnilimab is a humanized IgG1-κ antibody targeting to PD-1 [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ANB030. CAS No. 2412764-40-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9997. | |
| Rostafuroxin | Rostafuroxin (PST 2238), a digitoxigenin derivative, is an orally active and potent Na + ,K + -ATPase (ATP1A1) antognist. Rostafuroxin binds specifically to the ATP1A1 extracellular domain and blocks respiratory syncytial virus ( RSV )-triggered EGFR Tyr845 phosphorylation. Rostafuroxin has antihypertensive and anti-RSV activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PST 2238. CAS No. 156722-18-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12283. | |
| Rosuvastatin | Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC 50 of 11 nM. Rosuvastatin potently blocks hERG current with an IC 50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZD 4522. CAS No. 287714-41-4. Pack Sizes: 1 mg. Product ID: HY-17504A. | |
| Rosuvastatin Calcium | Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC 50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC 50 of 195 nM [2]. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Rosuvastatin hemicalcium; ZD 4522 Calcium. CAS No. 147098-20-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-17504. | |
| Rosuvastatin (Calcium) (Standard) | Rosuvastatin (Calcium) (Standard) is the analytical standard of Rosuvastatin (Calcium). This product is intended for research and analytical applications. Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC 50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC 50 of 195 nM [2]. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Rosuvastatin hemicalcium (Standard); ZD 4522 Calcium (Standard). CAS No. 147098-20-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17504R. | |
| Rosuvastatin-d6 sodium | Rosuvastatin-d 6 (sodium) is deuterium labeled Rosuvastatin. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 2070009-41-3. Pack Sizes: 1 mg; 5 mg; 500 μg. Product ID: HY-17504BS1. | |
| Rosuvastatin Sodium | Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC 50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC 50 of 195 nM [2]. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZD 4522 Sodium; X-Plended Sodium; Crestor Sodium. CAS No. 147098-18-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-17504B. | |
| Rotenone | Rotenone is a mitochondrial electron transport chain complex I inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. Uses: Scientific research. Group: Natural products. CAS No. 83-79-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B1756. | |
| Rotenone (Standard) | Rotenone (Standard) is the analytical standard of Rotenone. This product is intended for research and analytical applications. Rotenone is a mitochondrial electron transport chain complex I inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. Uses: Scientific research. Group: Natural products. CAS No. 83-79-4. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B1756R. | |
| Rotigotine | Rotigotine is a potent dopamine receptor agonist with K i values of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors and dopamine D1 receptor. Rotigotine a partial agonist of the 5-HT1A receptor , and an antagonist of the α2B-adrenergic receptor. Rotigotine can be used for parkinson's disease (PD) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-0923; (-)-N 0437. CAS No. 99755-59-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-75502. | |
| Rotigotine Hydrochloride | Rotigotine Hydrochloride (N-0923 Hydrochloride) is a full agonist of dopamine receptor , a partial agonist of the 5-HT1A receptor , and an antagonist of the α2B-adrenergic receptor , with K i of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-0923 Hydrochloride. CAS No. 125572-93-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0007. | |
| Rovafovir etalafenamide | Rovafovir etalafenamide (GS-9131), a proagent of the adenosine nucleotide analogue GS-9148, is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Rovafovir etalafenamide is potent and active against a variety of NRTI mutants, and shows potent anti-HIV-1 activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9131. CAS No. 912809-27-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19851. | |
| Rovalpituzumab | Rovalpituzumab is a humanized monoclonal antibody against delta-like protein 3 (DLL3). Rovalpituzumab can be used in the synthesis of antibody-drug conjugate (ADC), Rovalpituzumab Tesirine [1]. Rovalpituzumab has activity against small cell lung cancer (SCLC) [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1613313-01-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99043. | |
| Rovelizumab | Rovelizumab is a humanized monoclonal leukointegrin antibody. Rovelizumab is a monoclonal antibody directed against the CD11/CD18 cell adhesion proteins. Rovelizumab can be used for research of multiple sclerosis (MS), hemorrhagic shock, myocardial infarction (MI) and stroke [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 339086-79-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99891. | |
| Roxadustat | Roxadustat is an orally active hypoxia-inducible factor (HIF) prolyl-hydroxylase (PHD) inhibitor (HIF-PHI) that promotes erythropoiesis through increasing endogenous erythropoietin, improving iron regulation, and reducing hepcidin [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FG-4592. CAS No. 808118-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-13426. | |
| Roxatidine Acetate Hydrochloride | Roxatidine Acetate Hydrochloride is a potent, selective, competitive and orally active histamine H2 -receptor antagonist. Roxatidine Acetate Hydrochloride has antisecretory potency against gastric acid secretion. Roxatidine Acetate Hydrochloride can also suppress inflammatory responses and can be used for gastric and duodenal ulcers research. Roxatidine Acetate Hydrochloride has antitumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HOE 760. CAS No. 93793-83-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0305A. | |
| Roxindole hydrochloride | Roxindole hydrochloride (EMD 38362), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors , with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT 1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT 1A (IC 50 =0.9 nM). Antipsychotic and antidepressant activities [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EMD 38362. CAS No. 108050-82-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-106100A. | |
| Roxithromycin | Roxithromycin (RU-28965) is an orally active semi-synthethic macrolide antibiotic. Roxithromycin inhibits protein biosynthesis in the elongation step by binding to 50S bacterial ribosome. Roxithromycin has antimicrobial, antiproliferative, anti-inflammatory, tumour vasculature inhibiting and lung injury ameliorating effects [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RU-28965. CAS No. 80214-83-1. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-B0435. | |
| (R)-Oxybutynin hydrochloride | (R)-Oxybutynin hydrochloride, a (R)-isomer of Oxybutynin hydrochloride, is an orally active muscarinic receptor antagonist. (R)-Oxybutynin hydrochloride has antimuscarinic, antispasmodic and anticholinergic activity, competitively antagonizes Carbachol-induced contractions. (R)-Oxybutynin hydrochloride can be used for researching incontinence due to neurogenic bladder dysfunction [1] [2] [3]. (R)-Oxybutynin (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aroxybutynin hydrochloride. CAS No. 1207344-05-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0267B. | |
| Royal Jelly acid | Royal Jelly Acid ((E)-Queen Bee Acid) is a major fatty acid found in royal jelly with oral bioavailability, exhibiting anti-inflammatory, anticancer, antimalarial, antiprotozoal, and neuroregulatory activities. Royal Jelly Acid can be used for research in various fields, including cancer, infections, immune inflammation, and neurological diseases [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. Alternative Names: (E)-Queen Bee Acid; (E)-10-Hydroxy-2-decenoic acid. CAS No. 14113-05-4. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-N1363. | |
| Rozanolixizumab | Rozanolixizumab (UCB7665), a humanized high-affinity anti-human neonatal Fc receptor (FcRn) monoclonal antibody (IgG4P), is used to the research of reducing pathogenic IgG in autoimmune and alloimmune diseases [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: UCB7665. CAS No. 1584645-37-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9979. | |
| RP-001 hydrochloride | RP-001 hydrochloride is a picomolar short-acting S1P1 (EDG1) selective agonist, with an EC 50 of 9 pM. RP-00 hydrochloride induces internalization and polyubiquitination of S1P1. RP-001 hydrochloride has little activity on S1P2-S1P4 and only moderate affinity for S1P5 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1781880-34-9. Pack Sizes: 1 mg. Product ID: HY-101939A. | |
| RPE65-IN-1 | RPE65-IN-1(Compound 16e) is a potent RPE65 inhibitor, which can be used in retinopathy-related research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1141779-07-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-149325. | |
| R-PE (R-Phycoerythrin) | R-Phycoerythrin is a phycobiliproteins could be isolated from Heterosiphonia japonica. R-Phycoerythrin is a potent fluorescent probe contains four chromophore-carrying subunits that exhibits extremely bright red-orange fluorescence. (λex=496 nm, λem=578 nm) [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 11016-17-4. Pack Sizes: 1 mg (22 mg/mL * 45 μL in buffer (buffer containing 60% (NH4)2SO4)); 5 mg (22 mg/mL * 227 μL in buffer (buffer containing 60% (NH4)2SO4)); 10 mg (22 mg/mL * 455 μL in buffer (buffer containing 60% (NH4)2SO4)). Product ID: HY-D0988. | |
| RPI-1 | RPI-1 is a specific, orally available 2-indolinone Ret tyrosine kinase inhibitor. RPI-1 inhibits proliferation, Ret tyrosine phosphorylation, Ret protein expression, and the activation of PLCgamma, ERKs and AKT in human medullary thyroid carcinoma TT cells. Antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 269730-03-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101246. | |
| (R)-Pirtobrutinib | (R)-Pirtobrutinib ((R)-LOXO-305) is a less active enantiomer of Pirtobrutinib. Pirtobrutinib (LOXO-305), a highly selective and non-covalent next generation BTK inhibitor, inhibits diverse BTK C481 substitution mutations [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-LOXO-305. CAS No. 2101700-14-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131328A. | |
| (R)-Praziquantel | (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 57452-98-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126057. | |
| (R)-Prinomastat | (R)-Prinomastat ((R)-AG3340) is the R-isomer of Prinomastat (HY-12170) (a MMP Inhibitor) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-AG3340; (R)-KB-R9896. CAS No. 207795-16-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-12170B. | |
| RR6 | RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC 50 of 540 nM for recombinant vanin-1. RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC 50 values of 40 nM, 41 nM and 87 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1351758-37-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18780. | |
| (R,R)-(+)-Hydrobenzoin | (R,R)-(+)-Hydrobenzoin is a chiral vicinal diol and an organic catalyst. (R,R)-(+)-Hydrobenzoin is used in asymmetric catalytic reactions [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 52340-78-0. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-59125. | |
| (R)-Roscovitine | (R)-Roscovitine (Seliciclib) is an orally bioavailable and selective CDKs inhibitor with IC 50 s of 0.2 μM, 0.65 μM, and 0.7 μM for CDK5 , Cdc2 , and CDK2 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Seliciclib; CYC202. CAS No. 186692-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-30237. | |
| (R,R)-Traxoprodil | (R,R)-Traxoprodil is the the (R,R)-enantiomer of Traxoprodil (HY-W018061). Traxoprodil (CP101,606) is a potent and selective NMDA antagonist and protect hippocampal neurons with an IC 50 of 10 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R,R)-CP101,606. CAS No. 134234-13-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W018061C. | |
| RRx-001 | RRx-001, a hypoxia-selective epigenetic agent and studied as a radio- and chem-sensitizer, triggers apoptosis and overcomes agent resistance in myeloma. RRx-001 exhibits potent anti-tumor activity with minimal toxicity [1]. RRx-001 is a dual small molecule checkpoint inhibitor by downregulating CD47 and SIRP-α [2]. RRx-001 is a potent inhibitor of G6PD and shows potent antimalarial activity [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 925206-65-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16438. | |
| RS 09 | RS09 is a LPS peptide mimic serves as a candidate to be considered as a new class of TLR4 agonist adjuvant. RS09 increases antibody production in a vaccine setting [1]. Uses: Scientific research. Group: Peptides. CAS No. 1449566-36-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P1439. | |
| RS-1 | RS-1 is a RAD51 activator, and also increases CRISPR/Cas9 -mediated knock-in efficiencies. Uses: Scientific research. Group: Signaling pathways. CAS No. 312756-74-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19793. | |
| RS-102221 hydrochloride | RS-102221 hydrochloride is a selective 5-HT2C receptor antagonist (K i =10 nM). RS-102221 hydrochloride shows nearly 100-fold selectivity for the 5-HT2C receptor as compared to the 5-HT2A and 5-HT2B receptors. RS-102221 hydrochloride can promote the differentiation of new nerve cells. RS-102221 hydrochloride increases food-intake and weight-gain in rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 187397-18-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101365A. | |
| RS102895 | RS102895 is a potent CCR2 antagonist, with an IC 50 of 360 nM, and shows no effect on CCR1. Uses: Scientific research. Group: Signaling pathways. CAS No. 300815-41-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-18611A. | |
| RS102895 hydrochloride | RS102895 hydrochloride is a potent CCR2 antagonist, with an IC 50 of 360 nM, and shows no effect on CCR1. Uses: Scientific research. Group: Signaling pathways. CAS No. 1173022-16-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-18611. | |
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