MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Niraxostat | Niraxostat (Y-700; Piraxostat) is an orally active xanthine oxidoreductase ( XOR ) inhibitor used in the study of hyperuricemia and other diseases in which XOR may be involved [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Y-700; Piraxostat. CAS No. 206884-98-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-14669. |  |
| Niridazole | Niridazole is an anaerobic and microaerophilic bacterial inhibitor with IC 50 values ranging from 0.0037 to 1.0 μg/mL [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BA-32644. CAS No. 61-57-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-119614. | |
| Nirmatrelvir | Nirmatrelvir (PF-07321332) is a potent and orally active SARS-CoV 3C-like protease (3CL PRO ) inhibitor. Nirmatrelvir (PF-07321332) targets to the SARS-CoV-2 virus and can be used for COVID-19 research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-07321332. CAS No. 2628280-40-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-138687. | |
| Nirogacestat | Nirogacestat (PF-3084014) is a reversible, orally bioavailable, noncompetitive, and selective γ-secretase inhibitor with an IC 50 of 6.2 nM. Inhibition of Notch signaling by Nirogacestat while minimizing gastrointestinal toxicity presents a promising approach for research of Notch receptor-dependent cancers [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-3084014. CAS No. 1290543-63-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15185. | |
| Nirogacestat dihydrobromide | Nirogacestat dihydrobromide (PF-3084014 dihydrobromide) is a reversible, orally bioavailable, noncompetitive, and selective ?-secretase inhibitor with an IC50 of 6.2 nM. Inhibition of Notch signaling by Nirogacestat dihydrobromide while minimizing gastrointestinal toxicity presents a promising approach for research of Notch receptor-dependent cancers[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-3084014 dihydrobromide; PF-03084014 dihydrobromide. CAS No. 1962925-29-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15185B. | |
| Nirsevimab | Nirsevimab (MEDI8897) is a recombinant monoclonal antibody against human respiratory syncytial virus ( RSV ). Nirsevimab has neutralizing activity against RSV A and RSV B viruses, with IC 50 values of 5.42 ng/mL and 9.71 ng/mL, respectively. Nirsevimab can be used for research on respiratory infections [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI8897. CAS No. 1989556-22-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99756. | |
| Nirvanol | Nirvanol (Ethylphenylhydantoin) is a metabolite of Mephenytoin (HY-B1184) that exerts anticonvulsant effects in the Maximal Electroshock (M.E.S.) seizure model in mice. The ED 50 of Nirvanol is 23 mg/kg (measured 30 minutes after intraperitoneal injection) and 30 mg/kg (measured 2 hours after intraperitoneal injection). Nirvanol shows potential for research in epilepsy-related neurological disorders [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ethylphenylhydantoin; Phenylethyihydantoin; Desmethylmephenytoin. CAS No. 631-07-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W012481. | |
| Nisevokitug | Nisevokitug (NIS-793) is a human, IgG2λ antibody targeting TGF-β ( TGFB1/TGFB2 ). Nisevokitug is expressed by CHO-K1 cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: NIS-793. CAS No. 2649854-92-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990009. | |
| Nisin | Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus species. Nisin has antibacterial and anti-inflammatory activity [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 1414-45-5. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-P1607. | |
| N-Isobutyrylglycine-d2 | N-Isobutyrylglycine-d 2 is the deuterium labeled N-Isobutyrylglycine[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1219795-05-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W141928S1. | |
| Nisoldipine | Nisoldipine (BAY-k 5552; Sular) is an orally active and blood-brain barrier-penetrating dihydropyridine calcium antagonist, with greater vascular selectivity than other calcium channel antagonists. Nisoldipine inhibits calcium influx and blocks voltage-gated calcium channels. Nisoldipine dilates coronary and systemic arteries. Nisoldipine has antihypertensive and anti-anginal activity. Nisoldipine also displays neuroprotective and antiviral activity [1] [2] [7] [11]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-k 5552. CAS No. 63675-72-9. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-17402. | |
| N-Isopropyl-N'-phenyl-p-phenylenediamine | N-Isopropyl-N'-phenyl-p-phenylenediamine is an antioxidant used in rubber manufacturing to reduce the detrimental effect of oxygen. N-Isopropyl-N'-phenyl-p-phenylenediamine can cause contact allergy [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 101-72-4. Pack Sizes: 10 mM * 1 mL; 100 g. Product ID: HY-W130442. | |
| N-Isovaleroylglycine | N-Isovaleroylglycine is an acyl glycine and could be used as a biomarker for the predispositon for weight gain and obesity. Uses: Scientific research. Group: Natural products. CAS No. 16284-60-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W015464. | |
| Nisoxetine | Nisoxetine is a potent and selective inhibitor of noradrenaline transporter (NET) , with a K d of 0.76 nM. Nisoxetine is an antidepressant and local anesthetic, it can block voltage-gated sodium channels [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 53179-07-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1704. | |
| Nisoxetine hydrochloride | Nisoxetine hydrochloride is a potent and selective inhibitor of noradrenaline transporter (NET) , with a K d of 0.76 nM. Nisoxetine hydrochloride is an antidepressant and local anesthetic, it can block voltage-gated sodium channels [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 57754-86-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1704A. | |
| Nitazoxanide | Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC 50 of 2.4 μM [1]. Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NTZ; NSC 697855. CAS No. 55981-09-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B0217. | |
| NITD008 | NITD008 is a potent and selective flaviviruse inhibitor which can inhibit Dengue Virus Type 2 (DENV-2) with an EC 50 of 0.64 μM. NITD008 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 7-Deaza-2'-C-acetylene-adenosine. CAS No. 1044589-82-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-12957. | |
| NITD-688 | NITD-688 is an orally active pan-serotype inhibitor of the dengue virus NS4B protein. NITD-688 can be used in the research of dengue virus (DENV)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2407227-31-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138543. | |
| Nitecapone | Nitecapone (OR-462) is an orally active and short-acting catechol-O-methyltransferase (COMT) inhibitor with gastroprotective and antioxidant properties. Nitecapone (OR-462) scavenges reactive oxygen and nitric radicals and prevents lipid peroxidation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OR-462. CAS No. 116313-94-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-106842. | |
| Nitenpyram | Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC 50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 150824-47-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-B0820. | |
| Nitidine chloride | Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis , inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A , ERK and c-Src/FAK associated signaling pathway, also has anti-inflammatory activity. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 13063-04-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0498. | |
| Nitisinone | Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase ( 4-HPPD ) inhibitor with an IC 50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NTBC; Nitisone; SC0735. CAS No. 104206-65-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0607. | |
| Nitrendipine | Nitrendipine (BAY-E-5009), an analogue of Nifedipine (HY-B0284), is a dihydropyridine calcium channel blocker with vasodilator action. Nitrendipine has antihypertensive effect [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-E-5009. CAS No. 39562-70-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-B0424. | |
| Nitrilotriacetic acid | Nitrilotriacetic acid is an aminotricarboxylic acid. Nitrilotriacetic acid can be used as a chelating agent, forming coordination compounds with metal ions [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Triglycollamic acid. CAS No. 139-13-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W030778. | |
| Nitrobenzylthioinosine | Nitrobenzylthioinosine is an ENT1 transporter inhibitor that binds to ENT1 transporter with high affinity. Nitrobenzylthioinosine is a photoaffinity probe for adenosine uptake sites in brain. Nitrobenzylthioinosine can cross the blood-brain barrier[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NBMPR. CAS No. 38048-32-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W010936. | |
| Nitro blue tetrazolium chloride | Nitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: NBT. CAS No. 298-83-9. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg. Product ID: HY-15925. | |
| Nitrocefin | Nitrocefin is a highly activated, chromogenic cephalosporin derivative. Nitrocefin is a chromogenic ?-lactamase substrate. Nitrocefin undergoes a distinctive color change from yellow to red as the amide bond in the ?-lactam ring is hydrolyzed by ?-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on ?-lactamase-resistant antibiotics[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 41906-86-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108913. | |
| Nitrochin | Nitrochin (4-NQO) is a chemical carcinogen. Nitrochin induces oncostatin-M (OSM) in esophageal cells. Nitrochin induces DNA damage, and induces apoptosis via a p53-dependent mitochondrial signaling pathway[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-NQO. CAS No. 56-57-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-33354. | |
| Nitrofen | Nitrofen is a selective contact herbicide. Nitrofen is a retinal dehydrogenase (belongs to the ALDH family) and protoporphyrinogen oxidase inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1836-75-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1877. | |
| Nitroflurbiprofen | Nitroflurbiprofen is a cyclooxygenase ( COX ) inhibitor with nitric oxide (NO)-donating properties, modulates the increased intrahepatic vascular tone in portal hypertensive cirrhotic rats. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HCT 1206; NO-flurbiprofen; Nitroxybutyl flurbiprofen. CAS No. 158836-71-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00013. | |
| Nitrofurantoin | Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67-20-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-A0090. | |
| Nitrofurantoin (Standard) | Nitrofurantoin (Standard) is the analytical standard of Nitrofurantoin. This product is intended for research and analytical applications. Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67-20-9. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-A0090R. | |
| Nitrofurazone | Nitrofurazone (Nitrofural) is a broad spectrum antibiotic that has oral activity. Nitrofurazone is a nitro-aromatic drug. Nitrofurazone is active against both Gram-positive and Gram-negative bacteria [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Nitrofural. CAS No. 59-87-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0226. | |
| Nitrosoglutathione | Nitrosoglutathione (GSNO), a exogenous NO donor and a substrate for rat alcohol dehydrogenase class III isoenzyme, inhibits cerebrovascular angiotensin II-dependent and -independent AT1 receptor responses [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSNO; RVC-588; S-Nitroso-L-glutathione. CAS No. 57564-91-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-D0845. | |
| Nitroxoline | Nitroxoline (8-Hydroxy-5-nitroquinoline), an antibiotic , is an orally active antibiofilm agent. Nitroxoline reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc. Nitroxoline can be used for the urinary tract infections and cancer research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 8-Hydroxy-5-nitroquinoline; 5-Nitro-8-quinolinol. CAS No. 4008-48-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1159. | |
| Nitroxynil | Nitroxynil, anthelmintic agent, is active against parasites in both adult and immature stages. Nitroxynil is widely used for the research of infection of Fasciola hepatica [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1689-89-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W049875. | |
| Nivalenol | Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum , is a fungal metabolite present in agricultural product [1]. Nivalenol induces cell death through caspase -dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect [2]. Uses: Scientific research. Group: Natural products. CAS No. 23282-20-4. Pack Sizes: 1 mg. Product ID: HY-N6801. | |
| Nivasorexant | Nivasorexant is a potent orexin receptor antagonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-539313. CAS No. 1435480-40-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147294. | |
| Nivatrotamab | Nivatrotamab (Hu3F8-BsAb) is a humanized anti- GD2/CD3 bispecific antibody. Nivatrotamab is a CD3- and GD2-specific bsAb-based T-cell engager. Nivatrotamab can be used in research of neuroblastoma [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Hu3F8-BsAb. CAS No. 2278244-14-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99757. | |
| Nivolumab | Nivolumab is a programmed death receptor-1 ( PD-1 ) blocking human IgG4 antibody to treat advanced (metastatic) non-small cell lung cancer. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS-936558; ONO-4538; MDX-1106. CAS No. 946414-94-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9903. | |
| Nizatidine | Nizatidine is a potent and orally active histamine H 2 receptor antagonist, can be used for the research of stomach and intestines ulcers. Nizatidine works by decreasing the secretion of gastric acid the stomach makes and prevent ulcers from coming back after they have healed in animal models [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 76963-41-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B0310. | |
| Nizatidine-d3 | Nizatidine-d 3 is the deuterium labeled Nizatidine. Nizatidine is a potent and orally active histamine H2 receptor antagonist, can be used for the research of stomach and intestines ulcers. Nizatidine works by decreasing the secretion of gastric acid the stomach makes and prevent ulcers from coming back after they have healed in animal models[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1246833-99-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0310S. | |
| NK1 receptor antagonist 2 | NK1 receptor antagonist 2 is a NK1 receptor antagonist. NK1 receptor antagonist 2 can be used for the research of tinnitus and hearing loss [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 579475-17-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145250. | |
| NK-252 | NK-252 is a potential Nrf2 activator, which exhibits a great Nrf2 -activating potential. Uses: Scientific research. Group: Signaling pathways. CAS No. 1414963-82-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19734. | |
| NKH477 | NKH477 (Colforsin dapropate hydrochloride) directly activates the catalytic unit of adenylate cyclase and increases intracellular cAMP. NKH477 is a forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 exerts an antiproliferative effect in vivo with an altered cytokine profile to inhibit the acute rejection of rat orthotopic lung allografts[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Colforsin dapropate hydrochloride. CAS No. 138605-00-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103193. | |
| N-Lactoyl-Phenylalanine | N-Lactoyl-Phenylalanine is a blood-derived signaling metabolite that can be induced by exercise. N-Lactoyl-Phenylalanine can reduce obesity and improve glucose tolerance [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Lac-Phe. CAS No. 183241-73-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-150012. | |
| N-Lactylleucine | N-Lactylleucine is an endogenous metabolite that can be identified in patients with the intermediate type of maple syrup urine disease [1]. Uses: Scientific research. Group: Peptides. CAS No. 112757-17-2. Pack Sizes: 5 mg. Product ID: HY-164805. | |
| N-Lactylvaline | N-Lactylvaline is an endogenous metabolite that can be identified in patients with the intermediate type of maple syrup urine disease [1]. Uses: Scientific research. Group: Peptides. CAS No. 70190-98-6. Pack Sizes: 5 mg. Product ID: HY-164804. | |
| N-Lauroyl-L-alanine | N-Lauroyl-L-alanine is an alanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 52558-74-4. Pack Sizes: 10 g; 25 g; 100 g. Product ID: HY-W009379. | |
| N-Lauroylsarcosine | N-lauroylsarcosine is an anionic surfactant, and can be used as a permeation enhancer. The mixture of N-lauroylsarcosine in 25-50% ethanol acts synergistically to increase skin permeability, which may be useful for transdermal drug delivery research [1]. Uses: Scientific research. Group: Peptides. CAS No. 97-78-9. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-W141881. | |
| NLRP3/AIM2-IN-3 | NLRP3/AIM2-IN-3 (compound 59) is a potent inhibitor with differential species specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. NLRP3/AIM2-IN-3 shows inhibitory efficacy against pyroptosis in THP-1 macrophages stimulated with LPS/nigericin, with an IC50 of 0.077 ± 0.008 ?M. NLRP3/AIM2-IN-3 disturbs the interaction of NLRP3 or AIM2 with the adaptor protein ASC and inhibited ASC oligomerization[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1787787-60-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144226. | |
| NLRP3-IN-11 | NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC 50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2769040-91-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148187. | |
| NLRP3-IN-18 | NLRP3-IN-18 (compound 13) is a potent NLRP3 inhibitor with an IC 50 value of ≤1.0 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2769040-06-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153554. | |
| NLRP3-IN-2 | NLRP3-IN-2, an intermediate substrate in the synthesis of glyburide, inhibits the formation of the NLRP3 inflammasome in cardiomyocytes and limits the infarct size following myocardial ischemia/reperfusion in the mouse, without affecting glucose metabolism [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 16673-34-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W011082. | |
| NLRP3-IN-25 | NLRP3-IN-25 (compound 32) is an orally available NLRP3 inhibitor with anti-inflammatory activity. NLRP3-IN-25 attenuates renal injury in doxorubicin-induced glomerulonephritis in mice. NLRP3-IN-25 inhibits IL-1β secretion in THP-1 cells with an IC 50 of 21 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2660230-90-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155463. | |
| NMD670 | NMD670 is an orally active inhibitor of skeletal muscle specific chloride channel ClC-1 with an EC 50 of 1.6 μM. NMD670 enhances neuromuscular transmission and improves muscle contraction and strength. NMD670 can be used in the study of muscle weakness and muscle fatigue [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2354321-33-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158183. | |
| NMDA | NMDA is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Uses: Scientific research. Group: Natural products. Alternative Names: N-Methyl-D-aspartic acid. CAS No. 6384-92-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-17551. | |
| NMDI14 | NMDI14 is a nonsense mediated RNA decay (NMD) inhibitor. NMDI14 disrupts the SMG7-UPF1 interactions and inhibits NMD. Uses: Scientific research. Group: Signaling pathways. CAS No. 307519-88-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111374. | |
| N-Methoxy-N-methylacetamide | N-Methoxy-N-methylacetamide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 78191-00-1. Pack Sizes: 25 g. Product ID: HY-W001095. | |
| N-Methyl-4-pyridone-3-carboxamide-d3 | N-Methyl-4-pyridone-3-carboxamide-d 3 is deuterium labeled N-Methyl-4-pyridone-3-carboxamide. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1207384-47-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113472S. | |
| N-Methylbenzamide | N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor. N-Methylbenzamide has anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 613-93-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-135848. | |
| N-Methylbenzylamine | N-methylbenzylamine is a member of phenylmethylamines. N-methylbenzylamine can be found in carrot, which makes N-methylbenzylamine a potential biomarker for the consumption of these food products [1]. Uses: Scientific research. Group: Natural products. CAS No. 103-67-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W007426. | |
| (±)-N-Methylcoclaurine | (±)-N-Methylcoclaurine is a selective α2-adrenoceptor antagonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1472-62-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-155879. | |
| N-Methyldopamine hydrochloride | N-Methyldopamine hydrochloride is a precursor of adrenaline in the adrenal medulla. N-Methyldopamine hydrochloride is a modification of the dopamine (DA), and retains agonist activity at the DA1 receptor. N-Methyldopamine hydrochloride remains capable of universal surface coating and secondary reactions using the surface catechols. N-Methyldopamine hydrochloride can be used for heart failure research[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 62-32-8. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-W014728. | |
| N-Methylhydantoin | N-Methylhydantoin is a product of degradation of creatinine by bacteria. Uses: Scientific research. Group: Natural products. Alternative Names: 1-Methylhydantoin. CAS No. 616-04-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-113382. | |
| N-Methyliminodiacetic acid | 2,2'-(Methylazanediyl)diacetic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 4408-64-4. Pack Sizes: 5 g. Product ID: HY-W007872. | |
| N-Methyl-L-valine | N-Methyl-L-valine is a valine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 2480-23-1. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-20561. | |
| N-Methylmesoporphyrin IX | N-Methylmesoporphyrin IX (NMM), a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring A? fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for A? amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric A? environments, but emits strong fluorescence through stacking with the A? assemblies[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 142234-85-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133821. | |
| N-Methylnicotinamide | N-Methylnicotinamide is an endogenous metabolite with antithrombotic effect. N-Methylnicotinamide via production/release of prostacyclin inhibits arterial thrombosis development. N-Methylnicotinamide is also the N-methylation product from nicotinamide catalyzed by N-methyltransferase within nicotinate and nicotinamide metabolism pathway. N-Methylnicotinamide is a potential biomarker in miR-1291-altered pancreatic cell metabolism and tumorigenesis [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 114-33-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-124124. | |
| N-Methylparoxetine | N-Methylparoxetine is a derivative of Paroxetine that induces Apoptosis NSCLC cells by activating mitogen-activated protein kinase ( MAPK ). N-Methylparoxetine has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 110429-36-2. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-Z3832. | |
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