MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| RS-127445 | RS-127445 is a selective, high affinity, orally bioavailable 5-HT 2B receptor antagonist with a pK i of 9.5. RS-127445 shows 1000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199864-87-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15419A. |  |
| RS-127445 hydrochloride | RS-127445 hydrochloride is a selective, high affinity, orally bioavailable 5-HT 2B receptor antagonist with a pK i of 9.5. RS-127445 hydrochloride shows 1000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199864-86-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15419. | |
| RS17 | RS17 is an anti-tumor peptide designed to bind specifically to the CD47 molecule and block the interaction between CD47 and its ligand, SIRPα, on the surface membrane of macrophages. The main regulatory mechanism of RS17 is to prevent CD47 from transmitting selective phagocytosis signals to SIRPα by binding to CD47 , so that macrophages do not recognize tumor cells as their own tissue, but phagocytose them as foreign substances, thereby inhibiting immune escape of tumor cells. RS17 can be used to study the mechanism of anti-tumor response and immune escape [1]. Uses: Scientific research. Group: Peptides. CAS No. 2415545-08-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10420. | |
| (R,S)-4-Hydroxy Cyclophosphamide-d4 Preparation Kit | (R,S)-4-Hydroxy Cyclophosphamide-d 4 Preparation Kit is the deuterium labeled (R,S)-4-Hydroxy Cyclophosphamide Preparation Kit. (R,S)-4-Hydroxy Cyclophosphamide is an isomer of 4-Hydroxycyclophosphamide, the active metabolite of the cytotoxic alkylating agent Cyclophosphamide (HY-17420) [1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1329838-09-6. Pack Sizes: 2.5 mg. Product ID: HY-132451S. | |
| RS 504393 | RS 504393 is a selective CCR2 chemokine receptor antagonist ( IC 50 values are 89 nM and > 100 μM for inhibition of human recombinant CCR2 and CCR1 receptors respectively). Uses: Scientific research. Group: Signaling pathways. CAS No. 300816-15-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15418. | |
| RS 67333 hydrochloride | RS 67333 hydrochloride is a potent and selective 5-HT4 receptor (5-HT4R) partial agonist with a pK i of 8.7 in guinea-pig striatum. RS 67333 hydrochloride exhibits lower affinities at several other receptors including 5-HT1A, 5-HT1D, 5-HT2A, 5-HT2C, dopamine D1, D2 and muscarinic M1-M3 receptors. RS 67333 hydrochloride has neuroprotective effects, and can be used for Alzheimer's disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 168986-60-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101341. | |
| RSV-IN-1 | RSV-IN-1 is a human respiratory syncytical virus (hRSV) inhibitor, with an IC 50 of 0.11 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 861139-16-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-112673. | |
| (R)-(+)-tert-Butylsulfinamide | (R)-(+)-tert-Butylsulfinamide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (R)-2-Methylpropane-2-sulfinamide. CAS No. 196929-78-9. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-40228. | |
| (R)-Tetrahydrofuran-2-carboxylic acid | (R)-(+)-2-Tetrahydrofuroic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (R)-(+)-Tetrahydrofuran-2-carboxylic acid. CAS No. 87392-05-0. Pack Sizes: 5 g; 25 g. Product ID: HY-W005223. | |
| (R)-Thalidomide | (R)-Thalidomide ((R)-(+)-Thalidomide) is the R-enantiomer of Thalidomide. (R)-Thalidomide has psychomotor stabilizing properties [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-(+)-Thalidomide. CAS No. 2614-6-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-14658B. | |
| RU.521 | RU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation. RU.521 suppresses dsDNA-activated reporter activity with an IC 50 of 0.7 μM. RU.521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome (AGS) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RU320521. CAS No. 2262452-06-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114180. | |
| RU 58841 | RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen. RU 58841 has a dramatic effect on hair regrowth [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PSK-3841; HMR-3841. CAS No. 154992-24-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10561. | |
| Ru(acac)3 | Ru(acac)3 (Tris(acetylacetonato)ruthenium (III)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Tris(acetylacetonato)ruthenium (III). CAS No. 14284-93-6. Pack Sizes: 1 g. Product ID: HY-W020958. | |
| Rubiadin | Rubiadin is a dihydroxy anthraquinone isolated from Rubia cordifolia. Rubiadin has a potent antixidant activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 117-02-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0444. | |
| Rubiadin-1-methyl ether | Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65 [1]. Uses: Scientific research. Group: Natural products. CAS No. 7460-43-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N1956. | |
| Rubitecan | Rubitecan (RFS 2000), a Camptothecin derivative, is an orally active topoisomerase I inhibitor with broad antitumor activity, and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: RFS 2000; 9-Nitrocamptothecin. CAS No. 91421-42-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13744. | |
| Ruboxistaurin | Ruboxistaurin (LY333531) is an orally active, selective PKC beta inhibitor ( K i =2 nM). Ruboxistaurin exhibits ATP dependent competitive inhibition of PKC beta I with an IC 50 of 4.7 nM. Ruboxistaurin inhibits PKC beta II with an IC 50 of 5.9 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY333531. CAS No. 169939-94-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10195. | |
| Ruboxistaurin hydrochloride | Ruboxistaurin (LY333531) hydrochloride is an orally active, selective PKC beta inhibitor ( K i =2 nM). Ruboxistaurin hydrochloride exhibits ATP dependent competitive inhibition of PKC beta I with an IC 50 of 4.7 nM. Ruboxistaurin hydrochloride inhibits PKC beta II with an IC 50 of 5.9 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY333531 hydrochloride. CAS No. 169939-93-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10195B. | |
| Ruboxistaurin mesylate | Ruboxistaurin (LY333531) mesylate is an orally active, selective and ATP competitive PKCβ inhibitor with IC 50 values of 4.7 and 5.9 nM for PKCβI and PKCβII, respectively. Ruboxistaurin mesylate can be used for the research of eye disorders, heart failure and diabetes [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY333531 mesylate. CAS No. 192050-59-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-10195A. | |
| Rucaparib | Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K i of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG014699; PF-01367338. CAS No. 283173-50-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10617A. | |
| Rucaparib monocamsylate | Rucaparib (AG014699) monocamsylate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K i of 1.4 nM for PARP1. Rucaparib monocamsylate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib monocamsylate has the potential for castration-resistant prostate cancer (CRPC) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG014699 monocamsylate; PF-01367338 monocamsylate. CAS No. 1859053-21-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-102003. | |
| Rucaparib phosphate | Rucaparib (AG014699) phosphate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K i of 1.4 nM for PARP1. Rucaparib phosphate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib phosphate has the potential for castration-resistant prostate cancer (CRPC) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-014699 phosphate; PF-01367338 phosphate. CAS No. 459868-92-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10617. | |
| Rufinamide | Rufinamide (E 2080; CGP 33101; RUF 331) is a novel anticonvulsant compound that can inhibit Na + current activation, and be used in the research of Lennox-Gastaut syndrome. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 33101; E 2080; RUF 331. CAS No. 106308-44-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0042. | |
| Rufloxacin hydrochloride | Rufloxacin hydrochloride (MF-934 hydrochloride) is a fluoroquinolone antibacterial, inhibits B-cell differentiation in human mononuclear cells, inhibits Topo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MF-934 hydrochloride. CAS No. 106017-08-7. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0902A. | |
| Runcaciguat | Runcaciguat is an orally active stimulator of soluble guanylate cyclase , and is used in the research of cardiovascular and renal diseases combined with selective partial adenosine A1 receptor agonists [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1101042. CAS No. 1402936-61-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109136. | |
| Runimotamab | Runimotamab is an IgG1-κ humanized chimeric antibody targeting CD3E and HER2 [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2361325-98-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99896. | |
| Rupatadine | Rupatadine (UR-12592) is a potent, orally active and long-lasting dual PAF/H1 antagonist, with K i s of 0.55 μM and 0.1 μM, respectively. Rupatadine can be used for the research of allergic rhinitis and urticaria [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UR-12592. CAS No. 158876-82-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-13511. | |
| Rupatadine Fumarate | Rupatadine (UR-12592) Fumarate is a potent, orally active and long-lasting dual PAF/H1 antagonist, with K i s of 0.55 μM and 0.1 μM, respectively. Rupatadine Fumarate can be used for the research of allergic rhinitis and urticaria [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UR-12592 Fumarate. CAS No. 182349-12-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-13511A. | |
| RuPhos | RuPhos is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 787618-22-8. Pack Sizes: 5 g; 10 g; 25 g. Product ID: HY-W007432. | |
| Rupintrivir | Rupintrivirvr (AG7088), an antiviral agent, is a potent, selective and irreversible inhibitor of human rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC 50 of 0.023 μM. Rupintrivirvr shows immune-modulatory effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG7088. CAS No. 223537-30-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-106161. | |
| Ruplizumab | Ruplizumab (BG 9588) is a humanized monoclonal anti- CD40L (TNF Receptor) IgG1κ antibody. Ruplizumab has the potential for systemic lupus erythematosus disease research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BG 9588; Anti-Human CD40L Recombinant Antibody. CAS No. 220651-94-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99315. | |
| Rusalatide acetate | Rusalatide acetate (TP508 amide acetate), a regenerative peptide, mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity [1]. Uses: Scientific research. Group: Peptides. Alternative Names: TP508 amide acetate. CAS No. 875455-82-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-105069A. | |
| Ruscogenin | Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus , attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 472-11-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-N0496. | |
| Rusfertide | Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin , reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: PTG-300. CAS No. 1628323-80-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P10272. | |
| RU-SKI 43 hydrochloride | RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC 50 of 850 nM. RU-SKI 43 hydrochloride reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. RU-SKI 43 hydrochloride has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1782573-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-18366A. | |
| Rutaecarpine | Rutaecarpine, an alkaloid of Evodia rutaecarpa , is an inhibitor of COX-2 with an IC 50 value of 0.28 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Rutecarpine. CAS No. 84-26-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0147. | |
| Rutin | Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Rutoside; Quercetin 3-O-rutinoside. CAS No. 153-18-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-N0148. | |
| Rutin hydrate | Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Rutoside hydrate; Quercetin 3-O-rutinoside hydrate. CAS No. 207671-50-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N0148A. | |
| Rutin (Standard) | Rutin (Standard) is the analytical standard of Rutin. This product is intended for research and analytical applications. Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 153-18-4. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N0148R. | |
| Rutin trihydrate | Rutin (Rutoside) trihydrate is a multifunctional natural flavonoid glycoside. Rutin trihydrate has been demonstrating excellent antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic properties. Cardioprotective and neuroprotective activities [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Rutoside trihydrate; Quercetin 3-O-rutinoside trihydrate. CAS No. 250249-75-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W013075. | |
| Ruxolitinib | Ruxolitinib (INCB18424) is an orally active and selective JAK1/2 inhibitor with IC 50 s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3 [1]. Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INCB18424. CAS No. 941678-49-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-50856. | |
| Ruxolitinib phosphate | Ruxolitinib phosphate (INCB018424 phosphate) is a potent JAK1/2 inhibitor with IC 50 s of 3.3 nM/2.8 nM, respectively, showing more than 130-fold selectivity over JAK3. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INCB018424 phosphate. CAS No. 1092939-17-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50858. | |
| (R)-Verapamil hydrochloride | (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is an orally active P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport. (R)-Verapamil hydrochloride induces Apoptosis and inhibits L-type calcium channels BZPcc, DHPcc and PLLcc. (R)-Verapamil hydrochloride has anti-septic shock and anti-diabetic effects [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-(+)-Verapamil hydrochloride. CAS No. 38176-02-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135336. | |
| RW3 | RW3 is a small cationic hexapeptide with amphiphilic properties. RW3 targets the plasma membrane of bacteria and works by inhibiting cell respiration and cell wall synthesis. RW3 shows high biological activity against gram-positive bacteria and does not show significant cytotoxic or hemolytic effects in previous studies. RW3 quickly kills 97% of the initial colony forming units (CFU) within 10 minutes at twice the minimum inhibitory concentration ( MIC ). RW3 can be used in antimicrobial and antifungal studies [1]. Uses: Scientific research. Group: Peptides. CAS No. 359632-11-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10281. | |
| RX-3117 | RX-3117 (TV-1360) is a potent and orally active anticancer and antimetabolite agent. RX-3117 inhibits DNA methyltransferase 1 (DNMT1). RX-3117 shows antiproliferative and anti-tumour activity. RX-3117 induces cell cycle arrest at S phase and apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TV-1360; Fluorocyclopentenylcytosine. CAS No. 865838-26-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-15228. | |
| Ryanodine | Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca 2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa. Uses: Scientific research. Group: Natural products. CAS No. 15662-33-6. Pack Sizes: 1 mg. Product ID: HY-103306. | |
| (S)-10-Hydroxycamptothecin | (S)-10-Hydroxycamptothecin (10-HCPT;10-Hydroxycamptothecin) is a DNA topoisomerase I inhibitor of isolated from the Chinese plant Camptotheca accuminata. (S)-10-Hydroxycamptothecin exhibits a remarkable apoptosis -inducing effect. (S)-10-Hydroxycamptothecin has the potential for hepatoma, gastric carcinoma, colon cancer and leukaemia treatment [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 10-HCPT; 10-Hydroxycamptothecin. CAS No. 19685-09-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0095. | |
| (S)-[1,1'-Binaphthalene]-2,2'-diamine | (S)-[1, 1'-Binaphthalene]-2, 2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: S-(-)-2,2-Diamino-1,1-binaphthyl. CAS No. 18531-95-8. Pack Sizes: 250 mg; 1 g; 5 g. Product ID: HY-W007978A. | |
| S12 | S12 is a mutant RAS peptide containing the Gly (G) to Ser (S12) substitution. The sequence of the peptide is KLVVVGASGVGKS [1]. Uses: Scientific research. Group: Peptides. CAS No. 257872-93-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2361. | |
| (S)-(+)-1,2-Propanediol | (S)-(+)-1,2-Propanediol is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 4254-15-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-79334. | |
| S130 | S130 is a high affinity, selective inhibitor of ATG4B (a major cysteine protease) with an IC 50 of 3.24 μM. S130 suppresses autophagy flux [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1160852-22-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112818. | |
| S-14506 hydrochloride | S-14506 hydrochloride is a potent 5-HT1A agonist, as well as 5-HT 2A/2C antagonist. S-14506 hydrochloride displays dopamine antagonist properties by blocking dopamine D2 receptors. S-14506 hydrochloride inhibits the in vivo binding of [3H]raclopride in striatum and olfactory bulbs. S-14506 hydrochloride has the potential for the research of anxiolytic agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 286369-38-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110024. | |
| S-15535 | S-15535 is a highly selective 5-HT 1A receptor ligand. S-15535 is an antagonist of postsynaptic 5-HT 1A receptors and an agonist of presynaptic 5-HT 1A receptors. S-15535 can be used in research on psychiatric disorders, such as anti-anxiety [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 146998-34-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116076. | |
| S 17092 | S 17092 (S 17092-1) is an orally active cerebral prolyl-endopeptidase (PEP) inhibitor with an IC 50 of 1.2 nM. S 17092 inhibits cell apoptosis. S 17092 mechanism of action is to inhibit the activity of PEP, slowing down the degradation of neuroactive peptides and thus enhancing memory function. S 17092 can be used for the research of memory impairment and cognitive disorders associated with cerebral aging [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S 17092-1. CAS No. 176797-26-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15114. | |
| S186 | S186 is a new type of strontium-specific chelator. Uses: Scientific research. Group: Signaling pathways. CAS No. 97759-16-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13950. | |
| S 18986 | S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rodents. S 18986 activates the release of noradrenaline and acetylcholine in rat hippocampus and enhances rat memory in object-recognition tests [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 175340-20-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10936. | |
| (S)-1-Boc-3-aminopiperidine | (S)-1-Boc-3-aminopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (S)-(+)-3-Amino-1-boc-piperidine. CAS No. 625471-18-3. Pack Sizes: 10 g; 25 g. Product ID: HY-40029. | |
| (S)-1-Boc-3-aminopyrrolidine | (S)-1-Boc-3-aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 147081-44-5. Pack Sizes: 5 g; 10 g. Product ID: HY-40098. | |
| (S)-1-Boc-3-hydroxypiperidine | (S)-1-Boc-3-hydroxypiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 143900-44-1. Pack Sizes: 10 mM * 1 mL; 25 g; 50 g. Product ID: HY-40023. | |
| (S)-1-Boc-3-methylpiperazine | (S)-1-Boc-3-methylpiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 147081-29-6. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-40040. | |
| S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate | S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) and refers to the Alkyl-Chain composition. S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate is the linker portions of the molecules employed for mAb attachment purposes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2127875-65-2. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-129942. | |
| S1P1 agonist 1 | S1P1 Agonist 1 is a S1P1 agonist with immunomodulatory activities. Uses: Scientific research. Group: Signaling pathways. CAS No. 1220973-37-4. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-104069. | |
| (S)-(-)-1-Phenylethanamine | (S)-(-)-1-Phenylethanamine (S-(-)-α-Phenylethylamine; L-(-)-α-Methylbenzylamine) is a S-isomer of 1-Phenylethanamine (HY-W012848). 1-Phenylethanamine is a potential central nervous system stimulant and can be used to synthesize the tyrosine kinase inhibitor CLM3 (HY-164413) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-(-)-α-Phenylethylamine; L-(-)-α-Methylbenzylamine. CAS No. 2627-86-3. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-75095. | |
| S1PR1 modulator 1 | S1PR1 modulator 1 is a selective S1PR1 inhibitor, with a pIC 50 of 7.6, with >40- and >80-fold selectivity, over the other S1PR isoforms S1PR2/3/4 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2328109-05-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-126145. | |
| S1RA | S1RA (E-52862) is a highly selective σ1 receptor (σ1R) antagonist with K i s of 17 nM and 23.5 nM for human σ1R and guinea pig σ1R, respectively. S1RA has Moderate antagonistic activity for human 5-HT 2B receptor (K i = 328 nM). S1RA has antinociceptive effects in neuropathic pain models. S1RA prevents mechanical and cold hypersensitivity in Oxaliplatin (HY-17371)-treated mice [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-52862. CAS No. 878141-96-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-18099. | |
| S1RA hydrochloride | S1RA (E-52862) hydrochloride is an orally active and selective sigma-1 receptor ( σ1R ) antagonist with a K i value of 17 nM. S1RA hydrochloride shows good selectivity against σ2R (K i >1000 nM). S1RA hydrochloride is a human 5-HT2B receptor antagonist with an IC 50 value of 4.7 μM. S1RA hydrochloride inhibits neuropathic pain and activity-induced spinal sensitization [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-52862 hydrochloride. CAS No. 1265917-14-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-18099A. | |
| S2101 | S2101 is a lysine-specific demethylase 1 ( LSD1 ) inhibitor with an IC 50 of 0.99 μM, K i of 0.61 μM and K inact /K i of 4560 M/s [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1239262-36-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110277. | |
| S2116 | S2116, a N-alkylated tranylcypromine (TCP) derivative, is a potent lysine-specific demethylase 1 (LSD1) inhibitor. S2116 increases H3K9 methylation and reciprocal H3K27 deacetylation at super-enhancer regions. S2116 induces apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by repressing transcription of the NOTCH3 and TAL1 genes. S2116 significantly retardes the growth of T-ALL cells in xenotransplanted mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2262489-89-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136522. | |
| (S)-2-(2-((tert-Butoxycarbonyl)amino )propanamido)acetic acid | (S) -2- (2- ( (tert-Butoxycarbonyl) amino) propanamido) acetic acid is a Glycine (HY-Y0966) derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 28782-78-7. Pack Sizes: 5 g. Product ID: HY-W019684. | |
| S-23 | S-23 is an orally active selective androgen receptor modulator (SARM) with a K i of 1.7 nM. S-23 induces androgen receptor (AR)-mediated transcriptional activation in CV-1 cells. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1010396-29-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112257. | |
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