MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Salinomycin | Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, selectively inhibits the growth of gram-positive bacteria. Salinomycin is a potent inhibitor of Wnt/β-catenin signaling, blocks Wnt-induced LRP6 phosphorylation. Salinomycin shows selective activity against human cancer stem cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Procoxacin. CAS No. 53003-10-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15597. |  |
| Salipurpin | Salipurpin (Apigenin 5-glucoside) is a flavonoid compound isolated from the branches and leaves of Cephalotaxus fortunei , which has certain anti-inflammatory activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Apigenin 5-glucoside. CAS No. 28757-27-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2883. | |
| S-Allyl-L-cysteine | S-Allyl-L-cysteine, one of the organosulfur compounds found in AGE, possess various biological effects including neurotrophic activity, anti-cancer activity, anti-inflammatory activity. Uses: Scientific research. Group: Natural products. CAS No. 21593-77-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W013573. | |
| Salmeterol | Salmeterol (GR33343X) is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC 50 s of 9.6, 6.1, and 5.9, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR33343X. CAS No. 89365-50-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14302. | |
| Salmeterol-d3 | Salmeterol-d 3 is a deuterium labeled Salmeterol. Salmeterol is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 497063-94-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135119. | |
| Salmeterol xinafoate | Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC 50 s of 9.6, 6.1, and 5.9, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 33343X xinafoate. CAS No. 94749-08-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17453. | |
| Salsalate | Salsalate is a potent antirheumatic drug with oral activity that reduces irritation during gastric absorption and avoids direct inhibition of cyclooxygenase. Salsalate not only has significant anti-inflammatory effects, but also reduces blood sugar levels, improves insulin resistance, and reduces the expression of cytokines. Salsalate can protect mice from metabolic disorders caused by high-fat diet and effectively improve the symptoms of type 2 diabetes, atherosclerosis and non-alcoholic steatohepatitis [1] [2 ] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Salicylsalicylic acid; Disalicylic acid. CAS No. 552-94-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B1245. | |
| Salubrinal | Salubrinal is a cell-permeable and selective inhibitor of eIF2α dephosphorylation [1]. Salubrinal acts as a dual-specificity phosphatase 2 ( Dusp2 ) inhibitor and suppresses inflammation in anti-collagen antibody-induced arthritis [2]. Salubrinal has antiviral activity against HSV-1 and inhibits dephosphorylation of eIF2α mediated by the HSV-1 protein ICP34.5 [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 405060-95-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15486. | |
| Salvianolic acid A | Salvianolic acid A could protect the blood brain barrier through matrix metallopeptidase 9 (MMP-9) inhibition and anti-inflammation. Uses: Scientific research. Group: Natural products. CAS No. 96574-01-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0318. | |
| Salvianolic acid B | Salvianolic acid B is an active ingredient of Salvia miltiorrhiza, which has been widely applied in China for the management of various microcirculation-related disorders, such as cardiovascular disease, cerebrovascular disease, and diabetic vascular complication. Uses: Scientific research. Group: Natural products. Alternative Names: Lithospermic acid B. CAS No. 121521-90-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N1362. | |
| Salvianolic acid D | Salvianolic acid D, isolated from Salvia miltiorrhiza , is a potential antiplatelet activity compound [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 142998-47-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0320. | |
| Salvigenin | Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties. Salvigenin inhibits H 2 O 2 -induced cell apoptosis [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Psathyrotin. CAS No. 19103-54-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N1318. | |
| Salvinorin B | Salvinorin B is the metabolite produced by Salvia divinorum. Salvinorin B is also the main metabolite of Salvinorin A in rhesus monkey blood [1]. Uses: Scientific research. Group: Natural products. CAS No. 92545-30-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-110252. | |
| Samalizumab | Samalizumab (ALXN 6000) is a humanized monoclonal antibody that specifically binds to CD200 and blocks its ligation to the CD200 receptor (CD200R). Samalizumab can be used for multiple myeloma and B-cell chronic lymphocytic leukemia research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ALXN 6000. CAS No. 1073059-33-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99400. | |
| Samatasvir | Samatasvir (IDX71) is a potent, orally active NS5A inhibitor of HCV replication. Samatasvir is effective and selective against infectious HCV and replicons, with EC 50 s falling within a tight range of 2 to 24 pM in genotype 1 through 5 replicons [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IDX719; IDX18719. CAS No. 1312547-19-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16784. | |
| Samelisant | Samelisant (SUVN-G3031) is a potent and selective histamine H3 receptor (H3R) inverse agonist with good brain penetration and oral bioavailability. Samelisant has a similar binding affinity towards human (hH3R; K i =8.7 nM) and rat (rH3R;K i =9.8 nM) H3R indicating no inter-species differences. Samelisant can be used for the research of sleep-related disorders [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SUVN-G3031. CAS No. 1394808-20-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120124. | |
| Samidorphan | Samidorphan (ALKS-33) is an orally active opioid system modulator that has a high affinity for binding with μ?opioid, κ?opioid, and δ?opioid receptors. Samidorphan acts as an antagonist at μ?opioid receptors and acts as a partial agonist at k-opioid and δ?opioid receptors. Samidorphan primarily acts as an opioid receptor antagonist in vivo [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALKS-33; RDC-0313. CAS No. 852626-89-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123689. | |
| (S)-AMPA | (S)-AMPA (L-AMPA), an active S-enantiomer of AMPA, is a potent and selective AMPA receptor agonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-AMPA. CAS No. 83643-88-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100815A. | |
| Samrotamab | Samrotamab is a humanized IgG1-κ chimeric antibody targeting LRRC15 [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PR-1498487. CAS No. 2052591-32-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99899. | |
| SAMS | SAMS peptide is a specific substrate for the AMP-activated protein kinase ( AMPK ). Uses: Scientific research. Group: Peptides. CAS No. 125911-68-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0136. | |
| Sancycline | Sancycline (6-Demethyl-6-deoxytetracycline) acts by reversibly binding to the 30 S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome a site similar to tetracycline (HY-A0107). Sancycline, four linearly fused six-membered rings with four stereocenters, is a rare semi-synthetic tetracycline (HY-A0107) prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bonomycin; 6-Demethyl-6-deoxytetracycline. CAS No. 808-26-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17466. | |
| Sandaracopimaric acid | Sandaracopimaric acid is a diterpenoid with anti-inflammatory effect. Sandaracopimaric acid reduces the contraction of phenylephrine-induced pulmonary arteries with an EC 50 of 43.93 μM [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 471-74-9. Pack Sizes: 1 mg. Product ID: HY-133594. | |
| Sanfetrinem | Sanfetrinem (GV104326) is a β-lactamase-stable antibiotic. Sanfetrinem has broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GV104326. CAS No. 156769-21-0. Pack Sizes: 1 mg. Product ID: HY-106922. | |
| Sanfetrinem sodium | Sanfetrinem (GV104326) sodium is a beta-lactamase-stable antibiotic. Sanfetrinem sodium has broad-spectrum activity against gram-positive and gram-negative bacteria [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GV104326 sodium. CAS No. 141611-76-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106922A. | |
| Sanguinarine chloride | Sanguinarine (Sanguinarin) chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis , can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB. Uses: Scientific research. Group: Natural products. Alternative Names: Sanguinarin chloride; Sanguinarium chloride; Pseudochelerythrine chloride. CAS No. 5578-73-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0052A. | |
| SANT-1 | SANT-1, a potent Smo antagonist, inhibits Hedgehog signaling. SANT-1 shows IC 50 s of 20 nM and 30 nM in Shh-LIGHT2 and SmoA1-LIGHT2 assay, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304909-07-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100224. | |
| Santalol | Santalol is a mixture of α and β-isomer santalol. α-Santalol is found in sandalwood oil. α-Santalol is a promising anti-cancer agent against cancers such as oral, breast, prostate and skin cancer. Santalol has sedative activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 11031-45-1. Pack Sizes: 25 mg; 50 mg. Product ID: HY-N2059. | |
| Santin | Santin is a flavonol isolated from Dodonaea uscosa [1]. Uses: Scientific research. Group: Natural products. CAS No. 27782-63-4. Pack Sizes: 1 mg. Product ID: HY-N11423. | |
| Santonin | Santonin is an active principle of the plant Artemisia cina , which is formely used to treat worms [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Alpha-Santonin. CAS No. 481-06-1. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1761. | |
| Sapacitabine | Sapacitabine is an orally available nucleoside analog proagent that is structurally related to cytarabine. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CS682; CYC682. CAS No. 151823-14-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16445. | |
| Sapanisertib | Sapanisertib (INK-128; MLN0128; TAK-228) is an orally available, ATP-dependent mTOR1/2 inhibitor with an IC 50 of 1 nM for mTOR kinase. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INK-128; MLN0128; TAK-228. CAS No. 1224844-38-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13328. | |
| Sapelizumab | Sapelizumab is a CHO-expressed humanized antibody targeting IL-6Ra/CD126. Sapelizumab has a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Sapelizumab can refer to Human IgG2 kappa, Isotype Control (HY-P99002). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1535963-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990662. | |
| Sapienic acid sodium | Sapienic acid sodium is a fatty acid commonly found on the skin and in mucosa. Sapienic acid sodium has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. Sapienic acid sodium is active against Streptococcus sanguinis , Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 217477-25-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130187A. | |
| Saponins | Saponins (Saponin) is a class of chemical compound of glycosides found in particular abundance in various plant species. In plants, Saponins may serve as anti-feedants, and to protect the plant against microbes and fungi [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Saponin. CAS No. 8047-15-2. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-100597. | |
| Sappanchalcone | Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 94344-54-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-59001. | |
| Sappanone A | Sappanone A is a homoisoflavanone which exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB. Sappanone can attenuate allergic airway inflammation in Ovalbumin-induced asthma [1]. Uses: Scientific research. Group: Natural products. CAS No. 102067-84-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-113556. | |
| Sapropterin dihydrochloride | Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin also drives autoimmunity. Sapropterin can be used in study of phenylketonuria (PKU) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (6R)-BH4 dihydrochloride; (6R)-Tetrahydro-L-biopterin dihydrochloride. CAS No. 69056-38-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0124A. | |
| Saquinavir | Saquinavir(Ro 31-8959) is an HIV Protease inhibitor used in antiretroviral therapy. Saquinavir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 1.36 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 31-8959. CAS No. 127779-20-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17007. | |
| Saquinavir mesylate | Saquinavir Mesylate (Ro 31-8959/003) is an HIV protease inhibitor used in retrovirus research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 31-8959/003. CAS No. 149845-06-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17003. | |
| SAR125844 | SAR125844 is a potent, selective, and ATP-competitive MET kinase inhibitor with the value of IC 50 is 4.2 nM and K i is 2.8 nM. SAR125844 has antitumor activity and can be used for the research of cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1116743-46-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16446. | |
| SAR131675 | SAR131675 is a potent and selective VEGFR3 inhibitor with an IC 50 of 23 nM. SAR131675 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1433953-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15458. | |
| SAR247799 | SAR247799 (S1P1 agonist 3) is an oral activity, selective G-protein-biased sphingosine-1 phosphate receptor-1 (S1P1 ) agonist, with EC 50 s rang from 12.6 to 493 nM in S1P1-overexpressing cells and HUVECs. SAR247799 can be used for the research of endothelial protection, including type-2 diabetes, metabolic syndrome [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S1P1 agonist 3. CAS No. 1315311-14-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115831. | |
| SAR407899 | SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC 50 of 135 nM for ROCK-2 , and K i s of 36 nM and 41 nM for human and rat ROCK-2 , respectively. SAR407899 shows stable inhibition of migrasome formation. Uses: Scientific research. Group: Signaling pathways. CAS No. 923359-38-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15687A. | |
| SAR407899 hydrochloride | SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC 50 of 135 nM for ROCK-2 , and K i s of 36 nM and 41 nM for human and rat ROCK-2 , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 923262-96-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15687. | |
| [Sar9,Met(O2)11]-Substance P | [Sar9,Met(O2)11]-Substance P is a tachykinin NK 1 receptor selective agonist. Uses: Scientific research. Group: Peptides. CAS No. 110880-55-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P1012. | |
| [Sar9,Met(O2)11]-Substance P TFA | [Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK 1 receptor selective agonist. Uses: Scientific research. Group: Peptides. CAS No. 2828433-10-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1012A. | |
| [Sar9] Substance P | [Sar9] Substance P is a potent and selective neurokinin (NK)-1 receptor agonist [1]. Uses: Scientific research. Group: Peptides. CAS No. 77128-75-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1738. | |
| Saracatinib | Saracatinib (AZD0530) is a potent Src family inhibitor with IC 50 s of 2.7 to 11 nM for c-Src , Lck , c-YES , Lyn , Fyn , Fgr , and Blk. Saracatinib shows high selectivity over other tyrosine kinases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD0530. CAS No. 379231-04-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10234. | |
| Sarafloxacin hydrochloride | Sarafloxacin (hydrochloride) (A-56620 (hydrochloride)) is a quinolone antibiotic agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A-56620 hydrochloride. CAS No. 91296-87-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0343A. | |
| Sarcosine | Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: N-Methylglycine; Sarcosin. CAS No. 107-97-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-101037. | |
| Sarcosine oxidase, Bacillus | Sarcosine oxidase, Bacillus (SAO) can catalyze the oxidative demethylation of sarcosine to generate glycine, H 2 O 2 , 5,10-CH 2 -tetrahydrofolate, which are often used in biochemical reactions [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAO. CAS No. 9029-22-5. Pack Sizes: 10 KU. Product ID: HY-P2861. | |
| Sardomozide dihydrochloride | Sardomozide dihydrochloride is an S-adenosylmethionine decarboxylase ( SAMDC ) inhibitor with an IC 50 of 5 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 48664A. CAS No. 138794-73-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-13746B. | |
| Sarecycline hydrochloride | Sarecycline hydrochloride is an orally active narrow-spectrum tetracycline derivative antibiotic. Sarecycline hydrochloride has anti-inflammatory activity. Sarecycline hydrochloride inhibits the activity of Gram-positive bacteria and several types of keratobacterium acnes. Sarecycline hydrochloride interferes with tRNA accommodation and tethers mRNA to the 70S ribosome. Sarecycline hydrochloride can be used to study moderate to severe acne [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: P-005672 hydrochloride. CAS No. 1035979-44-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-13858A. | |
| Saredutant | Saredutant is a selective NK2 receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR 48968; SR 48968C. CAS No. 142001-63-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106910. | |
| Sarilumab | Sarilumab (Anti-Human IL6Rα, Human Antibody) is a human immunoglobulin G1 monoclonal antibody. Sarilumab, a interleukin-6 (IL-6) receptor antagonist, binds to the IL-6 receptor with high affinity and inhibits cis and trans signaling by IL-6, resulting in reduced inflammation. Sarilumab can be used for the research of Rheumatoid arthritis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human IL6Rα, Human Antibody. CAS No. 1189541-98-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9916. | |
| Sarizotan | Sarizotan (EMD 128130) is an orally active serotonin 5-HT 1A receptor and dopamine receptor agonist. Sarizotan (EMD 128130) exhibits IC 50 values of 6.5 nM (rat 5-HT 1A ), 0.1 nM (human 5-HT 1A ), 15.1 nM (rat D 2 ), 17 nM (human D 2 ), 6.8 nM (human D 3 ) and 2.4 nM (human D 4.2 ), respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EMD 128130. CAS No. 351862-32-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100820. | |
| Saroglitazar | Saroglitazar is a novel peroxisome proliferator-activated receptor ( PPAR ) agonist with predominant PPARα and moderate PPARγ activity with EC 50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 495399-09-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19937. | |
| Saroglitazar magnesium | Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor ( PPAR ) agonist with predominant PPARα and moderate PPARγ activity with EC 50 values of 0.65 pM and 3 nM in HepG2 cells, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1639792-20-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19937A. | |
| Sarolaner | Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide. Sarolaner is an isoxazoline compound which shows efficacy against fleas and ticks on dogs, with a LC 80 value of 0.3 μg/mL against C. felis and a LC 100 value of 0.003 μg/mL against O. turicata [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-6450567. CAS No. 1398609-39-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16730. | |
| Sarpogrelate hydrochloride | Sarpogrelate hydrochloride (MCI-9042) is a selective 5-HT 2 R antagonist, with pK i s of 8.52, 6.57, and 7.43 for 5-HT 2A , 5-HT 2B , and 5-HT 2C receptors, respectively. Sarpogrelate hydrochloride displays selectivity over 5-HT 1 , 5-HT 3 , 5-HT 4 , α 1 -, α 2 - and β-adrenoreceptor, histamine H 1 , H 2 and muscarinic M 3 receptors. Sarpogrelate hydrochloride can be used for the research of vascular disease associated with thrombosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCI-9042. CAS No. 135159-51-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10564. | |
| Sarsasapogenin | Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities. Uses: Scientific research. Group: Natural products. Alternative Names: Parigenin; Sarsagenin. CAS No. 126-19-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0073. | |
| Sarsasapogenin (Standard) | Sarsasapogenin (Standard) is the analytical standard of Sarsasapogenin. This product is intended for research and analytical applications. Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities. Uses: Scientific research. Group: Natural products. CAS No. 126-19-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0073R. | |
| SARS-CoV-2-IN-6 | SARS-CoV-2-IN-6 is a SARS-CoV-2 3CLpro inhibitor that shows the most potent enzyme inhibitory IC 50 value of 73 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 2725749-22-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132886. | |
| SARS-CoV-2-IN-7 | SARS-CoV-2-IN-7 inhibits viral replication with a nanomolar IC 50 value (844 nM) in SARS-CoV-2-infected Vero E6 cells. Uses: Scientific research. Group: Signaling pathways. CAS No. 2570461-66-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141841. | |
| SARS-CoV-2 Mpro-IN-2 | SARS-CoV-2 Mpro-IN-2 (compound GC-14) is a selective, low cytotoxic and non-covalent M pro inhibitor ( IC 50 =0.40 μM) with good anti-SARS-CoV-2 activity ( EC 50 =1.1 μM). SARS-CoV-2 Mpro-IN-2 can be used in COVID-19 studies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768834-39-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151482. | |
| SARS-CoV-2 nsp13-IN-1 | SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent nsp13 (non-structural protein 13) inhibitor. SARS-CoV-2 nsp13-IN-1 only inhibits nsp13 ssDNA + ATPase , with an IC 50 of 6 μM. SARS-CoV-2 nsp13-IN-1 does not inhibit ssDNA - ATPase. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1005304-44-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150622. | |
| SARS-CoV-2 nsp14-IN-3 | SARS-CoV-2 nsp14-IN-3 (4975) is an inhibitor of the SARS-CoV-2 Nsp14 N7-Methyltransferase ( IC 50 : 3.5 μM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2920574-16-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149321. | |
| SARS-CoV-2 nsp3-IN-1 | SARS-CoV-2 nsp3-IN-1 (Compound 15c) is a Mac1 ( SARS-CoV-2 nsp3 macrodomain ) inhibitor with the IC 50 value of 6.1 μM. SARS-CoV-2 nsp3-IN-1 can inhibit Mac1 ADP-ribosylhydrolase activity. SARS-CoV-2 nsp3-IN-1 demonstrates notable selectivity for coronavirus macrodomains, especially towards SARS-CoV-2 Mac1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2892105-43-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150062. | |
| SARS-CoV-IN-1 | SARS-CoV-IN-1 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-1 shows anti-Coronavirus activity with an EC 50 of 4.9 μM in Vero cells. SARS-CoV-IN-1 inhibits the 3D7 and W2 strains of P. falciparum with IC 50 s of 15.4 and 133.2 nM; and IC 90 s of 25.7 and 459.1 nM; respectively. Antimalarial and antiviral activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 888958-25-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-135855. | |
| SARS-CoV-IN-2 | SARS-CoV-IN-2 is an effective inhibitor of SARS-CoV replication. SARS-CoV-IN-2 shows anti-Coronavirus activity with an EC 50 of 1.9 μM in Vero cells. SARS-CoV-IN-2 inhibits the 3D7 and W2 strains of P. falciparum with IC 50 s of 21.5 and 30 nM; and IC 90 s of 51.0 and 99.9 nM; respectively. SARS-CoV-IN-2 reduces HIV-1 -induced cytopathic effect with an EC 50 of 2.9 μM in MT-4 cells. Antimalarial and Antiviral Activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 888958-26-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-135856. | |
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