MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Odanacatib | Odanacatib (MK-0822) is a potent and selective inhibitor of cathepsin K , with an IC 50 of 0.2 nM for human cathepsin K. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0822. CAS No. 603139-19-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10042. |  |
| Odesivimab | Odesivimab is a human monoclonal antibody, targeting Ebola virus glycoprotein with a K D value of 7.74 nM for recombinant histidine-tagged Makona strain Ebola virus glycoprotein ectodomain protein. Odesivimab can be used in research of Ebola virus infection [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN-3471. CAS No. 2135632-30-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99764. | |
| O-Desmethylangolensin | O-Desmethylangolensin is a metabolite of soy isoflavone, daidzein metabolized by gut microbiota. O-Desmethylangolensin possesses antioxidant activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 21255-69-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N4075. | |
| O-Desmethyl gefitinib | O-Desmethyl gefitinib is an active metabolite of Gefitinib in human plasma. The formation of O-desmethyl gefitinib is dependent on CYP2D6 activity. O-desmethyl gefitinib inhibits EGFR with an IC 50 of 36 nM in subcellular assays [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 847949-49-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100064. | |
| O-desmethyl Mebeverine acid | O-desmethyl Mebeverine acid is a metabolite of Mebeverine, which is a musculotropic antispasmodic drug. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mebeverine metabolite O-desmethyl Mebeverine acid. CAS No. 586357-02-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12771. | |
| O-Desmethyl quinidine | O-Desmethyl quinidine (Cupreidine) is an orally active metabolite of Quinine (HY-D0143). O-Desmethyl quinidine reduces frequency of cramps in rats with spinal cord injury and shows low blood toxicity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cupreidine. CAS No. 70877-75-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W037282. | |
| O-Desmethyltramadol hydrochloride | O-Desmethyltramadol (hydrochloride) is a primary active metabolite of Tramadol. O-Demethyltramadol is mainly responsible for its μ-opioid receptor-related analgesic effect. Tramadol is metabolized to O-Demethyltramadol mainly by the cytochrome P450 (CYP) 2D6 enzyme [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 185453-02-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-109054A. | |
| Odetiglucan | Odetiglucan is a novel β-glucan that is a potent immunostimulant and a Dectin-1 (CLEC7A) agonist. Odetiglucan activates innate immune effector cells and triggers a coordinated anti-cancer immune response [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BTH 1677; Imprime PGG. CAS No. 53238-80-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-147295. | |
| Odevixibat | Odevixibat (A4250) is a selective and orally active ileal apical sodium-dependent bile acid transporter ( ASBT ) inhibitor. Odevixibat decreases cholestatic liver and bile duct injury in mice model. Odevixibat has the potential for the treatment of primary biliary cirrhosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A4250. CAS No. 501692-44-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109120. | |
| Odiparcil | Odiparcil (SB-424323) is an orally active beta-d-thioxyloside analog with antithrombotic activity associated with a reduced risk of adverse bleeding events. Odiparcil (SB-424323) is indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-424323. CAS No. 137215-12-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10277. | |
| ODM-203 | ODM-203 is an orally active and selective FGFR/VEGFR inhibitor with IC 50 values of 6, 11, 16, 5, 9, 26 and 35 nM for FGFR3/1/2 and VEGFR3/2/1/4 , respectively. ODM-203 has strong anti-tumour activity and activates immune responses in the tumour microenvironment [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1430723-35-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119367. | |
| ODM-207 | ODM-207 (BET-IN-4) is a potent BET bromodomain protein ( BRD4 ) inhibitor, with an IC 50 of ≤ 1 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BET-IN-4. CAS No. 1801503-93-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111916. | |
| ODN 1018 | ODN 1018 (1018 ISS), an oligodeoxynucleotide, is a TLR-9 agonist. ODN 1018 is also a synthetic immunostimulatory sequence that can be used as vaccine adjuvant. Sequence: 5?-TGACTGTGAACGTTCGAGATGA-3?[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1018 ISS. CAS No. 937402-51-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150724. | |
| ODN 1018 sodium | ODN 1018 sodium, an oligodeoxynucleotide, is a TLR-9 agonist. ODN 1018 sodium is also a synthetic immunostimulatory sequence that can be used as vaccine adjuvant. Sequence: 5?-TGACTGTGAACGTTCGAGATGA-3?[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1018 ISS sodium. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150724C. | |
| ODN 1826 | ODN 1826 is a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist. ODN 1826 induces NO and iNOS production and enhances Apoptosis. ODN 1826 enhances immune surveillance. ODN 1826 increases aortic atherosclerotic plaque size. ODN 1826 has antitumor activity against lung cancer, glioma and melanoma[1][2][3][4][5][6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CpG 1826. CAS No. 202668-42-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-146245. | |
| ODN 1826 sodium | ODN 1826 sodium is a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist. ODN 1826 sodium induces NO and iNOS production and enhances Apoptosis. ODN 1826 sodium enhances immune surveillance. ODN 1826 sodium increases aortic atherosclerotic plaque size. ODN 1826 sodium has antitumor activity against lung cancer, glioma and melanoma[1][2][3][4][5][6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CpG 1826 sodium. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-146245C. | |
| ODN 2088 sodium | ODN 2088 sodium is a potent TLR3, TLR7 and TLR9 inhibitor. ODN 2088 sodium shows no cytotoxic. ODN 2088 inhibits the release of IFN-? and IL-6[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150738C. | |
| ODN 2216 sodium | ODN 2216 sodium is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. ODN 2216 sodium induces high amounts of IFN-? and IFN-?. ODN 2216 sodium induces IFN-? by pDC (plasmacytoid DC) and IL-12 (p40) production by DC (dendritic cells). ODN 2216 sodium stimulates IFN-? production in peripheral blood mononuclear cells (PBMC), which is indirect and mediated by IFN-?/?. ODN 2216 sodium can activate NK cells and promote IFN-? production of TCR-triggered CD4+ T cells[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150741C. | |
| ODN 2395 | ODN 2395 is a C class oligodeoxynucleotide and can be used as vaccine adjuvant. ODN 2395 is also a TLR9 agonist. Sequence: 5'-tcgtcgttttcggcgc:gcgccg-3'[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1254617-22-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150743. | |
| ODN D-SL01 sodium | ODN D-SL01 sodium, a class B CpG ODN (oligodeoxynucleotide), is a TLR9 agonist. ODN D-SL01 sodium has strong immunostimulatory activity in a variety of vertebrate species and has anticancer activity. ODN D-SL01 sequence: 5'- T-C-G-C-G-A-C-G-T-T-C-G-C-C-C-G-A-C-G-T-T-C-G-G-T-A-3'[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150748A. | |
| ODN TTAGGG | ODN TTAGGG (A151), inhibitory oligonucleotide (ODN), is a TLR9, AIM2 and cGAS antagonist. ODN TTAGGG is immunosuppressive and inhibits AIM2 inflammasome activation, as well as cGAS activation, by competing with DNA. ODN TTAGGG can be used in the study of lupus erythematosus and other related autoimmune diseases. ODN TTAGGG sequence: 5'-T-T-A-G-G-G-T-T-A-G-G-G-T-T-A-G-G-G-T-T-A-G-G-G-3'[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ODN A151. CAS No. 1801724-76-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150751. | |
| ODN TTAGGG sodium | ODN TTAGGG sodium, inhibitory oligonucleotide (ODN), is a TLR9, AIM2 and cGAS antagonist. ODN TTAGGG sodium is immunosuppressive and inhibits AIM2 inflammasome activation, as well as cGAS activation, by competing with DNA. ODN TTAGGG sodium can be used in the study of lupus erythematosus and other related autoimmune diseases. ODN TTAGGG sequence: 5'-T-T-A-G-G-G-T-T-A-G-G-G-T-T-A-G-G-G-T-T-A-G-G-G-3'[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ODN A151 sodium. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150751C. | |
| ODQ | ODQ is a potent and selective soluble guanylyl cyclase (sGC, nitric oxide-activated enzyme) inhibitor. ODQ enhances the pro-apoptotic effects of Cisplatin in human mesothelioma cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 41443-28-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101255. | |
| Odronextamab | Odronextamab is a stable humanized IgG4 CD20 ?×? CD3 bispecific antibody that binds to CD3 on T cells and CD20 on B cells, triggering anti-tumor activity. Odronextamab is expected to be used in oncology research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1801338-64-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99038. | |
| OF-1 | OF-1 is a potent pan-BRPF bromodomain (BRD) inhibitor, with IC 50 values of 270 nM, 1.2 μM for TRIM24 and BRPF1B, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 919973-83-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12518. | |
| Ofatumumab | Ofatumumab is a fully human anti-CD20 monoclonal antibody that induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity in CD20-expressing B lymphocytes [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 679818-59-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9961. | |
| Ofirnoflastum | Ofirnoflastum (Ofirnoflast) is a serine/ threonine-protein kinase Nek7 inhibitor, with anti inflammatory effect[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ofirnoflast. CAS No. 2731294-23-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-159520. | |
| Ofloxacin | Ofloxacin (Hoe-280) is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase. Ofloxacin shows inhibitory activity against vaccinia virus (VV). Uses: Scientific research. Group: Natural products. Alternative Names: Hoe-280. CAS No. 82419-36-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0125. | |
| Ofloxacin-d3 | Ofloxacin-d 3 is the deuterium labeled Ofloxacin[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Hoe-280-d3. CAS No. 1173147-91-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0125S. | |
| Oglufanide | Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus. Oglufanide inhibits vascular endothelial growth factor (VEGF). Oglufanide can stimulate the immune response to hepatitic C virus (HCV) and intracellular bacterial infections. Oglufanide shows antitumor and anti-angiogenesis activities [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: H-Glu-Trp-OH; L-Glutamyl-L-tryptophan. CAS No. 38101-59-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13718. | |
| Ogremorphin | Ogremorphin (OGM) is a G protein coupled sensor GPR68 inhibitor with anti-inflammatory and anti-tumor activities. Ogremorphin can inhibit the migration of human melanoma cells and induce ferroptosis in glioblastoma cells[1][2][3].. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OGM; GPR68-IN-1. CAS No. 352563-21-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-154954. | |
| OGT 2115 | OGT 2115 is a potent, cell-permeable and orally active heparanase inhibitor with an IC50 of 0.4 ?M. OGT 2115 has anti-angiogenic properties (IC50 of 1 ?M). OGT 2115 also inhibits heparan sulfate degradation activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 853929-59-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100898. | |
| OICR-9429 | OICR-9429 is high affinity WD repeat domain 5 (WDR5) inhibitor, competitively blocks WDR5 interaction with MLL protein via binding the central peptide-binding pocket of WDR5. OICR-9429 can suppress histone H3K4 trimethylation and can be used for the research of various cancers including non-MLL-rearranged leukaemia, colon, pancreatic, prostate cancer and bladder cancer (BCa) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1801787-56-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16993. | |
| Oil Red O | Oil Red O is a fat-soluble diazol dye, with a maximum absorption at 518 nm. Oil Red O stains neutral lipids and cholesteryl esters but not biological membranes. Oil Red O can be used for detecting and quantifying hepatic steatosis in mouse liver biopsies. Oil Red O staining efficiently helps to visualize the radical changes that occur in tissues as metabolic disease occurs and progresses [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1320-06-5. Pack Sizes: 25 g. Product ID: HY-D1168. | |
| o-Iodobenzoic acid | o-Iodobenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 2-Iodobenzoic acid. CAS No. 88-67-5. Pack Sizes: 25 g. Product ID: HY-77433. | |
| OJT008 | OJT008 is an inhibitor of MtMetAP1c. OJT008 inhibits NiCl 2 - and CoCl 2 activated MtMetAP1c with IC 50 s of 11 and 40 μM, respectively. OJT008 can used to study tuberculosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 256370-29-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157518. | |
| Okadaic acid | Okadaic acid, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid has a significantly higher affinity for PP2A ( IC 50 =0.1-0.3 nM), and inhibits PP1 ( IC 50 =15-50 nM), PP3 ( IC 50 =3.7-4 nM), PP4 ( IC 50 =0.1 nM), PP5 ( IC 50 =3.5 nM), but does not inhibit PP2C. Okadaic acid increases of phosphorylation of a number of proteins by inhibiting PP, and acts a tumor promoter. Okadaic acid induces tau phosphorylation [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 78111-17-8. Pack Sizes: 25 μg (124.2 μM * 250 μL in Ethanol). Product ID: HY-N6785. | |
| Okanin | Okanin, effective constituent of the flower tea Coreopsis tinctoria , attenuates LPS-induced microglial activation through inhibition of the TLR4 / NF-κB signaling pathways [1]. Uses: Scientific research. Group: Natural products. CAS No. 484-76-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N6673. | |
| Olacaftor | Olacaftor (VX-440) is a cystic fibrosis transmembrane conductance regulator ( CFTR ) modulator extracted from patent US9782408. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-440. CAS No. 1897384-89-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112267. | |
| Olanexidine hydrochloride | Olanexidine hydrochloride is a monobiguanide compound with bactericidal activity. Olanexidine probably binds to the cell membrane, destroys membrane integrity. Olanexidine hydrochloride is active against a wide range of bacteria, including Gram-positive and Gram-negative bacteria. Olanexidine exhibits the bactericidal concentration of 109 μg/mL for Gram-positive bacilli [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 146509-94-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125654A. | |
| Olanzapine | Olanzapine (LY170053) is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 ( K i =7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 ( K i =11 to 31 nM), muscarinic M1-5 ( K i =1.9-25 nM), and adrenergic α1 receptor ( K i =19 nM). Olanzapine is an atypical antipsychotic [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY170053. CAS No. 132539-06-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-14541. | |
| Olaparib | Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC 50 s of 5 and 1 nM for PARP1 and PARP2 , respectively. Olaparib is an autophagy and mitophagy activator [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD2281; KU0059436. CAS No. 763113-22-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g. Product ID: HY-10162. | |
| Olaparib (Standard) | Olaparib (Standard) is the analytical standard of Olaparib. This product is intended for research and analytical applications. Olaparib (AZD2281; KU0059436) is a potent and orally active PARP inhibitor with IC50s of 5 and 1 nM for PARP1 and PARP2, respectively. Olaparib is an autophagy and mitophagy activator[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD2281 (Standard); KU0059436 (Standard). CAS No. 763113-22-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10162R. | |
| Olaquindox | Olaquindox, a quinoxalin derivative, is an orally active antibiotic. Olaquindox stimulates growth and decreases intestinal mucosal immunity of piglets [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 23696-28-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0465. | |
| Olaratumab | Olaratumab (IMC-3G3; LY3012207) is an anti-platelet-derived growth factor receptor alpha ( PDGFRα ) human monoclonal IgG1 antibody with antitumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IMC-3G3; LY3012207. CAS No. 1024603-93-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9922. | |
| Olcegepant | Olcegepant (BIBN-4096) is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBN-4096; BIBN 4096BS. CAS No. 204697-65-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10095. | |
| Oleamide | Oleamide is an endogenous fatty acid amide which can be synthesized de novo in the mammalian nervous system, and has been detected in human plasma. Uses: Scientific research. Group: Natural products. CAS No. 301-02-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2327. | |
| Oleandomycin | Oleandomycin is a macrolide antibiotic structurally closely related to Erythromycin. Oleandomycin is similar to Erythromycin with antimicrobial activity. Oleandomycin inhibits protein synthesis by interference with translation of activated amino acids to nascent peptide chains on the ribosomes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3922-90-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-116010. | |
| Oleandrin | Oleandrin (PBI-05204) inhibits the Na + , K + -ATPase activity with an IC 50 of 620 nM. Uses: Scientific research. Group: Natural products. Alternative Names: PBI-05204. CAS No. 465-16-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13719. | |
| Oleanolic acid | Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities. Uses: Scientific research. Group: Natural products. Alternative Names: Oleanic acid; Caryophyllin. CAS No. 508-02-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0156. | |
| Oleclumab | Oleclumab (MEDI9447) is a human IgG1λ monoclonal antibody targeting CD73 and inhibits the exonuclease activity of the extracellular enzyme CD73. Oleclumab can adjust the composition of bone marrow and lymphoid infiltrating leukocyte populations in the tumor microenvironment and has anti-tumor activity [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI9447. CAS No. 1803176-05-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99039. | |
| Oleic acid | Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid [1]. Oleic acid is a Na + /K + ATPase activator [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 9-cis-Octadecenoic acid; 9Z-Octadecenoic acid. CAS No. 112-80-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N1446. | |
| Oleic acid-13C18 | Oleic acid- 13 C 18 is the 13 C labeled Oleic acid (HY-N1446). Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid [1]. Oleic acid is a Na+/K+ ATPase activator [2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: 9-cis-Octadecenoic acid- 13 C18; 9Z-Octadecenoic acid- 13 C18. CAS No. 287100-82-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N1446S2. | |
| Oleic acid-d9 | Oleic acid-d 9 is deuterium labeled Oleic acid (HY-N1446). Oleic acid is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activato [1] [2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: 9-cis-Octadecenoic acid-d9; 9Z-Octadecenoic acid-d9. CAS No. 2687960-84-3. Pack Sizes: 10 mg. Product ID: HY-N1446S5. | |
| Oleocanthal | Oleocanthal is a COX-1/2 enzyme inhibitor and a nonsteroidal anti-inflammatory agent. Oleocanthal is obtained from virgin olive oil [1]. Uses: Scientific research. Group: Natural products. CAS No. 289030-99-5. Pack Sizes: 5 mg. Product ID: HY-124481. | |
| Oleoyl coenzyme A lithium | Oleoyl coenzyme A (Oleoyl-CoA) lithium is a thioester of oleic acid and coenzyme A. Oleoyl coenzyme A lithium has a role as an Escherichia coli metabolite and a mouse metabolite [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Oleoyl-CoA lithium. CAS No. 188824-37-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-109591A. | |
| Oleoylethanolamide | Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis. Uses: Scientific research. Group: Natural products. Alternative Names: N-Oleoylethanolamide; Oleamide MEA; Oleic acid monoethanolamide. CAS No. 111-58-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107542. | |
| Oleoyl serotonin | Oleoyl Serotonin is a TRPV1 antagonist with IC 50 value of 2.57 μM for human TRPV1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1002100-44-8. Pack Sizes: 5 mg (113.47 mM * 100 μL in Ethanol); 10 mg (113.47 mM * 200 μL in Ethanol). Product ID: HY-109841. | |
| Olesoxime | Olesoxime (TRO 19622) is a mitochondrial -targeted neuroprotective compound with mean EC 50 value for increasing cell survival is 3.2±0.2 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TRO 19622; NSC 21311. CAS No. 22033-87-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14796. | |
| Oleuropein | Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity [1]. Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase [2]. Uses: Scientific research. Group: Natural products. CAS No. 32619-42-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0292. | |
| Oleuropein Aglycone | Oleuropein Aglycone (3,4-DHPEA-EA) is a polyphenol and the aglycone form of oleuropein (HY-N0292), formed by enzymatic, acidic or acetylated hydrolysis of oleuropein. Dietary intake of oleuropein Aglycone (50 mg/kg diet) increases the number of neuronal autophagic vesicles, reverses cognitive deficits in the TgCRND8 transgenic mouse model of Alzheimer's disease, and reduces the levels of histone deacetylase 2 ( HDAC2 ) in the cortex and hippocampus. Oleuropein Aglycone increases urinary norepinephrine, interscapular brown adipose tissue epinephrine, and UCP1 protein levels, and reduced plasma leptin levels and total abdominal adipose tissue weight in a rat model of high-fat diet-induced obesity. Oleuropein Aglycone also reduced lung neutrophil infiltration, lipid peroxidation, and IL-1β levels in a mouse model of carrageenan-induced pleurisy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3,4-DHPEA-EA. CAS No. 31773-95-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135115. | |
| Oleuropein (Standard) | Oleuropein (Standard) is the analytical standard of Oleuropein. This product is intended for research and analytical applications. Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity [1]. Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase [2]. Uses: Scientific research. Group: Natural products. CAS No. 32619-42-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0292R. | |
| Oleylamine, 80-90% | Oleylamine, 80-90% (cis-1-Amino-9-octadecene, 80-90%) is a long-chain primary alkylamine, which can be used in nanoparticle synthesis as a solvent, surfactant, and reducing agent. Oleylamine, 80-90% forms metastable complexes with metal ions, which can be controllably decomposed to produce nanoparticles. Oleylamine, 80-90% can control the morphology of nanoparticle, prevent the nanoparticle aggregation, and reduce metal precursors to metal nanoparticles [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: cis-1-Amino-9-octadecene, 80-90%. CAS No. 112-90-3. Pack Sizes: 100 g; 500 g. Product ID: HY-W011696. | |
| Olgotrelvir sodium | Olgotrelvir sodium is an orally active dual inhibitor of coronavirus main protease (Mpro) and human cell cathepsin ( Cathepsin L ). Olgotrelvir sodium can effectively inhibit both SARS-CoV-2 replication and entry into host cells [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STI-1558 sodium. CAS No. 2763596-72-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-156655A. | |
| Oligomycin | Oligomycin, an antifungal antibiotic, is an inhibitor of H + -ATP-synthase. Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 1404-19-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N6782. | |
| Oligomycin A | Oligomycin A (MCH 32), created by Streptomyces , acts as a mitochondrial F 0 F 1 -ATPase inhibitor, with a K i of 1 μM; Oligomycin A shows anti-fungal activity. Uses: Scientific research. Group: Natural products. Alternative Names: MCH 32. CAS No. 579-13-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-16589. | |
| Oligomycin B | Oligomycin B is an antibiotic isolated from marine Streptomyces , used as an eukaryotic ATP synthase inhibitor, induces apoptosis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 11050-94-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6784. | |
| Oligopeptide-10 | Oligopeptide-10 is a bioactive peptide with anti-microbial effect and has been reported used as a cosmetic ingredient [1]. Uses: Scientific research. Group: Peptides. CAS No. 466691-40-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5255. | |
| Olinciguat | Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IW-1701. CAS No. 1628732-62-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109066. | |
| O-Linked GlcNAc transferase substrate | O-Linked GlcNAc transferase substrate is a biological active peptide. (A peptide substrate of O-linked GlcNAc transferase (OGT), a eukaryotic glycosyltransferase that uses UDP-GlcNAc as a glycosyl donor.). Uses: Scientific research. Group: Peptides. CAS No. 954381-93-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5375. | |
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