MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Shikonin | Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC 50 of 6.5 μM [1]. Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor [2] and can also inhibit TNF-α and NF-κB pathway [3]. Shikonin decreases exosome secretion through the inhibition of glycolysis [4]. Shikonin inhibits AIM2 inflammasome activation [7]. Uses: Scientific research. Group: Natural products. Alternative Names: C.I. 75535; Isoarnebin 4. CAS No. 517-89-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0822. |  |
| (-)-SHIN1 | (-)-SHIN1 ((-)-RZ-2994) is an inactive (-) enantiomer of SHIN1 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-RZ-2994. CAS No. 2444764-09-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112066B. | |
| (+)-SHIN1 | (+)-SHIN1 ((+)-RZ-2994) is an active (+) enantiomer of SHIN1 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-RZ-2994. CAS No. 2443966-90-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112066A. | |
| SHLP2 | SHLP2 (Small humanin-like peptide 2) is a small molecule peptide encoded by mitochondrial DNA, belonging to mitochondria derived peptide. SHLP2 has the activity of regulating apoptosis and inhibits cell death. SHLP2 can be used in the study of diseases related to mitochondrial dysfunction and anti-aging diseases [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Small humanin-like peptide 2. CAS No. 1191923-93-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P10409. | |
| (S)-HN0037 | (S)-HN0037 is the (S)-isomer of HN0037 (HY-163529), a selective and orally active helicase-primase inhibitor that inhibits HSV replication by targeting the viral helicase-primase enzyme complex [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2233566-78-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-163529A. | |
| Shogaol | Shogaol ([6]-Shogaol), an active compound isolated from Ginger ( Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation. Uses: Scientific research. Group: Natural products. Alternative Names: [6]-Shogaol; 6-Shogaol. CAS No. 555-66-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14616. | |
| SHR-1701 | SHR-1701 (Retlirafusp alfa) is a bifunctional fusion protein targeting PD-L1 and TGF-β for cancer research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Retlirafusp alfa. CAS No. 2891860-17-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99944. | |
| Shz-1 | Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 326886-05-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108440. | |
| SI-2 hydrochloride | SI-2 (EPH 116 hydrochloride) is a highly promising SRC-3 inhibitor (PPI). SI-2 (EPH 116 hydrochloride) has a much improved toxicity and pharmacokinetic profile, with acceptable oral availability [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EPH 116 hydrochloride. CAS No. 1992052-49-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101447A. | |
| Sialyl-Lewis X | Sialyl-Lewis X (sLeX) is a sialylated fucosylated tetrasaccharide, an endogenous antigen. Sialyl-Lewis X is a high-affinity ligand for selectins (E-, P-, and L-selectin) [1]. Sialyl-Lewis X binds to ELAM-1 and CD62 and has the ability to inhibits CD62-mediated neutrophil recruitment to sites of inflammation [2]. Uses: Scientific research. Group: Natural products. Alternative Names: sLeX. CAS No. 98603-84-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W020790. | |
| Siamenoside I | Siamenoside I is one of the mogrosides that has several kinds of bioactivities. Uses: Scientific research. Group: Natural products. CAS No. 126105-12-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0612. | |
| SIB-1553A | SIB-1553A is an orally bioavailable nicotinic acetylcholine receptors (nAChRs) agonist, with selectivity for β4 subunit-containing nAChRs. SIB-1553A is also a selective neuronal nAChR ligand. SIB-1553A is a cognitive enhancer, and has therapeutic potential for the symptomatic treatment of Alzheimers disease and other cognitive disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 191611-89-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-107676. | |
| SIB-1757 | SIB-1757 is a highly selective and noncompetitive antagonist of mGlu5 receptor with an IC 50 of 0.4 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 31993-01-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102095. | |
| SIBA | SIBA (5'-Isobutylthioadenosine) is a transmethylation inhibitor ( SAH (HY-19528) analogue), with potent anti-proliferative activity. SIBA reversibly inhibits the production of HSV-1 by blocking methylation, specifically by blocking the 5' end-capping of viral mRNA. SIBA also inhibits the growth of tumour cells in vitro and metastatic spread in vivo. SIBA can be used in cancer, HSV-1 infection and anti-malaria studies [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5'-Isobutylthioadenosine; 5'-Deoxy-5'-isobutylthioadenosine. CAS No. 35899-54-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-18684. | |
| Sibeprenlimab | Sibeprenlimab (VIS649) is a humanized IgG2 monoclonal antibody which inhibits a proliferation-inducing ligand ( APRIL ). Sibeprenlimab suppresses pathogenic immunoglobulins ( IgA and IgM ), while preserving antibody responses to mRNA-based vaccines against SARS-COV-2. Sibeprenlimab reduces urinary protein-to-creatinine ratio (UPCR) and glomerular filtration rate (GFR). Sibeprenlimab is promising for the research of IgA nephropathy (IgAN) [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: VIS649. CAS No. 2382896-07-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99901. | |
| Sibiromycin | Sibiromycin is a naturally produced glycosylated pyrrolobenzodiazepines (PBDs). Sibiromycin is also a potent antitumor antibiotic that binds covalently to DNA in the minor groove at the NH2 of guanine [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 12684-33-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N9460. | |
| Sibrafiban | Sibrafiban (RO 48-3657) is the orally active, nonpeptide, double-proagent of Ro 44-3888 and a selective glycoprotein IIb/IIIa receptor antagonist. Sibrafiban inhibits platelet aggregation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO 48-3657. CAS No. 172927-65-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10309. | |
| Sibrotuzumab | Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody targets fibroblast activation protein ( FAP ). Sibrotuzumab can be used for the research of colorectal cancer and non-small cell lung cancer (NSCLC) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BIBH 1; Anti-Human FAP Recombinant Antibody. CAS No. 216669-97-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99269. | |
| (S)-(+)-Ibuprofen | (S)-(+)-Ibuprofen ((S)-Ibuprofen), a S(+)-enantiomer of Ibuprofen, is a potent COX-1 and COX-2 inhibitor with IC 50 s of 2.1 μM and 1.6 μM, respectively. (S)-(+)-Ibuprofen has analgesic, anti-inflammatory, anticancer and antipyretic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dexibuprofen. CAS No. 51146-56-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-78131A. | |
| Sifalimumab | Sifalimumab (MEDI-545) is an anti-IFNα monoclonal antibody. Sifalimumab suppresses the abnormal immune activity by binding to multiple interferon-alpha (IFNα) subtypes. Sifalimumab can be used in systemic lupus erythematosus (SLE) research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI-545; MDX 1103. CAS No. 1006877-41-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99219. | |
| σ1 Receptor antagonist-1 | σ1 Receptor antagonist-1 is a highly potent and selective sigma 1 receptor antagonist ( pK i =10.28). σ1 Receptor antagonist-1 inhibits cell growth, arrests cell cycle at G0/G1 phase and induces apoptosis of MCF-7/ADR cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1204401-49-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10815. | |
| Sigma-1 receptor antagonist 1 | Sigma - 1 receptor antagonist 1 (compound 137) is a potent and selective sigma-1 receptor (σ1R) antagonist, with a high binding affinity to σ1R receptor ( K i = 1.06 nM). Sigma - 1 receptor antagonist 1 exhibits antineuropathic pain activity and acts as a promising agent for the treatment of neuropathic pain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1639220-19-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125821. | |
| (±)-Sigmoidin A | (±)-Sigmoidin A is an active compound. (±)-Sigmoidin A can be used for the research of various biochemical [1]. Uses: Scientific research. Group: Natural products. CAS No. 176046-04-1. Pack Sizes: 1 mg. Product ID: HY-N8649. | |
| Sigvotatug | Sigvotatug is an anti- ITGB6 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2764774-90-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990764. | |
| Sildenafil | Sildenafil (UK-92480) is a potent phosphodiesterase type 5 ( PDE5 ) inhibitor with an IC 50 of 5.22 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK-92480. CAS No. 139755-83-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-15025. | |
| Sildenafil chlorosulfonyl | Sildenafil chlorosulfonyl is a synthetic intermediate in the synthesis of the phosphodiesterase 5 (PDE5) inhibitor Sildenafil (HY-15025). Uses: Scientific research. Group: Signaling pathways. CAS No. 139756-22-2. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W099761. | |
| Sildenafil citrate | Sildenafil citrate is a potent phosphodiesterase type 5 ( PDE5 ) inhibitor with IC 50 of 5.22 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK-92480 citrate. CAS No. 171599-83-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-15025A. | |
| Silmitasertib | Silmitasertib (CX-4945) is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC 50 values of 1 nM against CK2α and CK2α'. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CX-4945. CAS No. 1009820-21-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50855. | |
| Silodosin | Silodosin (KAD 3213; KMD 3213) is a potent, selective and orally active α1A-adrenergic receptor (α1A-AR) blocker. Silodosin exhibits high affinity for α1A-AR ( K i =0.036 nM), over 162-fold and 50-fold than for α1B-AR and α1D-AR with K i values of 21 nM and 2.0 nM, respectively. Silodosin is an effective and well-tolerated agent, it can be used for the investigation of LUTS/BPH [1] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KAD 3213; KMD 3213. CAS No. 160970-54-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10122. | |
| Siltuximab | Siltuximab is an anti- IL-6 ( interleukin-6 ) monoclonal antibody, and shows antitumor activity. Siltuximab can be used in Multicentric Castleman's Disease (MCD) and COVID-19 research [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CNTO-328. CAS No. 541502-14-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9956. | |
| Silver bis(trifluoromethanesulfonyl)imide | Silver bis(trifluoromethanesulfonyl)imide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Silver triflimide. CAS No. 189114-61-2. Pack Sizes: 250 mg; 1 g. Product ID: HY-W021005. | |
| Silver diethyldithiocarbamate | Silver diethyldithiocarbamate (SDDC) is an organic compound consisting of silver ions complexed with the ligand diethyldithiocarbamate. SDDC is mainly used as a reagent in analytical chemistry to detect the presence of copper, iron and other heavy metals in various materials. It acts as a chelating agent, binding to metal ions and forming stable complexes that can be easily analyzed using techniques such as UV-Vis spectroscopy. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Silver(1+) diethyldithiocarbamate. CAS No. 1470-61-7. Pack Sizes: 5 g; 10 g. Product ID: HY-W034674. | |
| Silver iodide | Silver iodide is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 7783-96-2. Pack Sizes: 5 g; 25 g. Product ID: HY-W019930. | |
| Silver nitrite | Silver nitrite is an inorganic compound with the chemical formula AgNO 2. Silver nitrite can inhibit cell division and bacterial growth by interfering with protein synthesis [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 7783-99-5. Pack Sizes: 5 g. Product ID: HY-W034067. | |
| Silver sulfadiazine | Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AgSD. CAS No. 22199-08-2. Pack Sizes: 1 g. Product ID: HY-B1497. | |
| Silybin | Silybin is a flavonolignan isolated from milk thistle ( Silybum marianum ) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Silibinin. CAS No. 802918-57-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0779A. | |
| (±)-Silybin | (±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Silibinin (mixture of Silybin A and Silybin B). CAS No. 36804-17-8. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg. Product ID: HY-139637. | |
| Silybin A | Silybin A (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration. Uses: Scientific research. Group: Natural products. Alternative Names: Silibinin A. CAS No. 22888-70-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13748. | |
| Silychristin | Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum , with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8 , and elicits a strong inhibition of T3 uptake with an IC 50 of 110 nM [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 33889-69-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0647. | |
| Silydianin | Silydianin is an active constituent of Silybium marianum , with exhibit anti-collagenase, antitumor and anti-elastase activities. Silydianin is a natural protein tyrosine phosphatase 1B (PTP1B) with an IC 50 of 17.38?μM. Silydianin has inhibitory effect on the in vitro production and release of oxidative products [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 29782-68-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0646. | |
| Silymarin | Silymarin is an extract of the milk thistle ( Silybum marianum ). Silymarin is an effective SARS-CoV-2 main protease (M pro ) inhibitor. Silymarin can significantly reduce tumor cell proliferation, angiogenesis as well as insulin resistance. Silymarin has the chemopreventive effect on hepatocellular carcinoma (HCC). Silymarin has the potential for COVID-19 research [1] [2] [4]. Uses: Scientific research. Group: Natural products. CAS No. 65666-07-1. Pack Sizes: 250 mg; 500 mg. Product ID: HY-N7073. | |
| Simazine | Simazine is a triazine herbicide widely used in agriculture, pot-plant and tree production. Simazine is phytotoxicity and not highly toxic to soil microflora and algae [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 122-34-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B2046. | |
| Simeprevir | Simeprevir (TMC435; TMC435350) is an oral, potent and highly specific hepatitis C virus (HCV) NS3/4A protease inhibitor with a K i of 0.36 nM. Simeprevir inhibits HCV replication with an EC 50 of 7.8 nM. Simeprevir also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir inhibits the main protease (M pro ) and the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2, and also modulates host immune responses [1] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TMC435; TMC435350. CAS No. 923604-59-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10241. | |
| Simethicone | Simethicone is an orally active defoamer. Simethicone reduces the surface tension of air bubbles in the gastrointestinal tract, causing them to be expelled by vomiting, exhalation or absorption into the bloodstream. Simethicone has potential applications in flatulence and colic [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 8050-81-5. Pack Sizes: 1 g; 5 g; 10 g; 50 g. Product ID: HY-109519. | |
| Simetryn | Simetryn is a herbicide with an IC50 value of 16.9-3.70 mg/L (79.3-17.4 microM). Uses: Scientific research. Group: Signaling pathways. CAS No. 1014-70-6. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1853. | |
| Simlukafusp alfa | Simlukafusp alfa (FAP-IL2v) is an immunocytokine comprising an antibody against fibroblast activation protein α ( FAPα ) and an IL-2 variant that only binds IL-2Rβ&gamma. Isotype: human IgG1 [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: FAP-IL2v. CAS No. 1776942-10-9. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P99902. | |
| (S)-Imlunestrant tosylate | (S)-Imlunestrant ((S)-LY-3484356) tosylate is an (S)-enantiomer of Imlunestrant (HY-145572). (S)-Imlunestrant tosylate can be used in research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-LY-3484356 tosylate. CAS No. 2408840-43-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145572B. | |
| Simnotrelvir | SARS-CoV-2-IN-41 (compound 2) is a potent SARS-CoV-2 3CL pro inhibitor with an IC 50 value of 0.022 μM. SARS-CoV-2-IN-41 shows antiviral effect [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SIM0417; SARS-CoV-2-IN-41. CAS No. 2920904-06-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-154965. | |
| Simtuzumab | Simtuzumab (AB 0024; GS 6624) is a monoclonal antibody directed against Lysyl oxidase like-2 ( LOXL2 ). Simtuzumab can be used for the research of primary sclerosing cholangitis (PSC) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AB 0024; GS 6624. CAS No. 1318075-13-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99047. | |
| Simufilam | Simufilam (PTI-125), a compound, can be uesd for screening of agent candidate. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTI-125. CAS No. 1224591-33-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-139142. | |
| Simufilam hydrochloride | Simufilam (PTI-125) hydrochloride, a compound, can be uesd for screening of agent candidate. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTI-125 hydrochloride. CAS No. 2480226-07-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139142B. | |
| Simvastatin | Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a K i of 0.2 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK 733. CAS No. 79902-63-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-17502. | |
| Simvastatin acid ammonium | Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Tenivastatin ammonium. CAS No. 139893-43-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119695A. | |
| Simvastatin (Standard) | Simvastatin (Standard) is the analytical standard of Simvastatin. This product is intended for research and analytical applications. Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a K i of 0.2 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK 733 (Standard). CAS No. 79902-63-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17502R. | |
| Sinapine | Sinapine is an alkaloid isolated from seeds of the cruciferous species. Sinapine exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic and radio-protective effects. Sinapine is also an acetylcholinesterase (AChE) inhibitor and can be used for the research of Alzheimers disease, ataxia, myasthenia gravis, and Parkinsons disease [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 18696-26-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N5077. | |
| Sinapine thiocyanate | Sinapine thiocyanate is an alkaloid isolated from seeds of the cruciferous species. Sinapine thiocyanate exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic and radio-protective effects. Sinapine thiocyanate is also an acetylcholinesterase (AChE) inhibitor and can be used for the research of Alzheimers disease, ataxia, myasthenia gravis, and Parkinsons disease [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 7431-77-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-N0450. | |
| Sinapinic acid | Sinapinic acid (Sinapic acid) is a phenolic compound isolated from Hydnophytum formicarum Jack. Rhizome, acts as an inhibitor of HDAC , with an IC 50 of 2.27 mM [1] , and also inhibits ACE-I activity [2]. Sinapinic acid posssess potent anti-tumor activity, induces apoptosis of tumor cells [1]. Sinapinic acid shows antioxidant and antidiabetic activities [2]. Sinapinic acid reduces total cholesterol, triglyceride, and HOMA-IR index, and also normalizes some serum parameters of antioxidative abilities and oxidative damage in ovariectomized rats [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Sinapic acid. CAS No. 530-59-6. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-W009732. | |
| Sinapultide | Sinapultide is a 21-amino-acid peptide that mimics the action of human surfactant protein-B (SP-B). Sinapultide can be used for synthetic phospholipids surfactants improvement [1]. Uses: Scientific research. Group: Peptides. CAS No. 138531-07-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2207. | |
| Sinapyl alcohol | Sinapyl alcohol is an orally active anti-inflammatory and antinociceptive agent. Sinapyl alcohol reduces the expression level of inducible NO synthase and COX-2 [1]. Uses: Scientific research. Group: Natural products. CAS No. 537-33-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W109812. | |
| Sincalide | Sincalide (Cholecystokinin octapeptide, CCK?8) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. CCK?8 is a major bioactive segment of CCK that retains most of the biological activities of CCK. CCK?8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. CCK?8 can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. CCK?8 is a major bioactive segment of CCK that retains most of the biological activities of CCK [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Cholecystokinin octapeptide; CCK-8; SQ19844. CAS No. 25126-32-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0093. | |
| Sincalide ammonium | Sincalide ammonium (Cholecystokinin octapeptide ammonium, CCK-8 ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK. CCK?8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide ammonium can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Cholecystokinin octapeptide ammonium; CCK-8 ammonium; SQ19844 ammonium. CAS No. 70706-98-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0093A. | |
| Sinensetin | Sinensetin is a methylated flavonoid found in fruits that has strong anti-vascular and anti-inflammatory properties. Uses: Scientific research. Group: Natural products. Alternative Names: Pedalitin permethyl ether. CAS No. 2306-27-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0297. | |
| Sinigrin | Sinigrin is a major glucosinolate present in plants of the Brassicaceae family. Sinigrin inhibits early-stage adipogenesis of 3T3-L1 adipocytes through the AMPK and MAPK signaling pathways. Sinigrin has potent anti-oxidant, anti-tumor and anti-inflammatory effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 3952-98-5. Pack Sizes: 10 mg; 25 mg. Product ID: HY-N0404. | |
| Sinigrin hydrate | Sinigrin (hydrate) is a natural aliphatic glucosinolate present in plants of the Brassicaceae family. Sinigrin (hydrate) exhibits anti-cancer, antibacterial, antifungal, antioxidant and anti-inflammatory activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 64550-88-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2423. | |
| Sinomenine | Sinomenine, an alkaloid extracted from Sinomenium acutum , is a blocker of the NF-κB activation [1]. Sinomenine also is an activator of μ-opioid receptor [2]. Uses: Scientific research. Group: Natural products. CAS No. 115-53-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-15122. | |
| Sinomenine hydrochloride | Sinomenine hydrochloride (Cucoline hydrochloride), an alkaloid extracted from Sinomenium acutum , is a blocker of the NF-κB activation [1]. Sinomenine also is an activator of μ-opioid receptor [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cucoline hydrochloride. CAS No. 6080-33-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-15122A. | |
| Sintilimab | Sintilimab (IBI308) is a safe and effectivel humanized IgG4 monoclonal antibody that binds to PD-1 with a K D value of 74 pM. Sintilimab blocks the interaction of PD-1 with its ligands (PD-L1 and PL-L2), consequently helping to restore the endogenous antitumour T-cell response. Sintilimab combined with prebiotics inhibits tumor volume and regulates immune cell subpopulation balance in lung adenocarcinoma mice. Sintilimab can be used for the research of classical Hodgkin's lymphoma, non-small cell lung cancer and oesophageal cancer [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IBI308. CAS No. 2072873-06-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99048. | |
| Sipatrigine | Sipatrigine (619C89), a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has the potential in the study for focal cerebral ischemia and stroke [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 619C89; BW 619C89. CAS No. 130800-90-7. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-108335. | |
| Sipavibart | Sipavibart is an anti- SARS-CoV-2 human IgG1 λ2 monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 lambda2, Isotype Control (HY-P990096). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AZD3152. CAS No. 2768288-97-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990766. | |
| Siplizumab | Siplizumab (MEDI-507) is a humanized IgG1 monoclonal antibody against CD2. Siplizumab depletes T cells, decreases T cell activation, inhibites T cell proliferation and enriches naïve and bona fide regulatory T cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI-507. CAS No. 288392-69-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99904. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.