MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Siponimod | Siponimod (BAF-312) is an orally active and selective sphingosine-1-phosphate ( S1P ) receptor modulator. Siponimod is selective for S1P 1 and S1P 5 over S1P 2 , S1P 3 , and S1P 4 , with EC 50 s of 0.4, 0.98, >10000, >1000, and 750 nM, respectively. Siponimod can be used for multiple sclerosis (MS) research [1] - [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAF-312. CAS No. 1230487-00-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-12355. |  |
| Siremadlin | Siremadlin (NVP-HDM201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NVP-HDM201; HDM201. CAS No. 1448867-41-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18658. | |
| Sirexatamab | Sirexatamab is an active peptide. Sirexatamab can be used for various biochemical studies. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2414962-49-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99906. | |
| SIRT1-IN-2 | SIRT1-IN-2 (compound 3h) is a potent and selective SIRT1 (silent information regulator 1) inhibitor, with an IC 50 of 1.6 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2470969-89-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146689. | |
| SIRT1-IN-3 | SIRT1-IN-3 (compound 3j) is a potent and selective SIRT1 inhibitor, with an IC 50 of 4.2 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2470969-91-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146690. | |
| SIRT1-IN-4 | SIRT1-IN-4 (Compound 8c) is a SIRT1 inhibitor, with an IC 50 of 10.04 μM. SIRT1-IN-4 can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 445405-18-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-169934. | |
| Sirtinol | Sirtinol is a sirtuin (SIRT) inhibitor, with IC 50 s of 48 μM, 57.7 μM and 131 μM for ySir2, hSIRT2 and hSIRT2, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 410536-97-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13515. | |
| Sirtuin-1 inhibitor 1 | Sirtuin-1 inhibitor 1 (Compound 8) is an inhibitor of Sirtuin -1 that plays important roles in obesity-induced diabetes and aging-related diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 945114-10-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156781. | |
| Sirukumab | Sirukumab (CNTO-136) is a humanized monoclonal anti- IL6 (Interleukin Related) IgG1κ antibody. Sirukumab binds to IL6 , preventing IL6-mediated signal transduction and activation of transcriptional activators, thereby blocking the downstream biological effects of IL6. Sirukumab can be used in the study of active lupus nephritis and rheumatoid arthritis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CNTO-136. CAS No. 1194585-53-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99316. | |
| Sisomicin | Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Antibiotic 6640; Rickamicin. CAS No. 32385-11-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1222A. | |
| Sisomicin sulfate | Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 53179-09-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-B1222. | |
| Sisomicin (sulfate) (Standard) | Sisomicin (sulfate) (Standard) is the analytical standard of Sisomicin (sulfate). This product is intended for research and analytical applications. Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 53179-09-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1222R. | |
| S-Isopropylisothiourea hydrobromide | S-Isopropylisothiourea (IPTU) hydrobromide is a potent and selective inhibitor of Nitric Oxide Synthase (NOS). S-Isopropylisothiourea (IPTU) hydrobromide is used in the research for hemorrhagic shock [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-isopropyl ITU; IPTU. CAS No. 4269-97-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-101304. | |
| Sisunatovir | Sisunatovir (RV521), an orally available inhibitor of the RSV protein, exhibits potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses, with IC 50 s of 1.4 nM and 1.0 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RV521. CAS No. 1903763-82-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123475. | |
| Sisunatovir hydrochloride | Sisunatovir (RV521) hydrochloride, an orally available inhibitor of the RSV fusion (RSV-F) protein, exhibits potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses, with IC 50 s of 1.4?nM and 1.0?nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RV521 hydrochloride. CAS No. 1903763-83-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123475A. | |
| Sitafloxacin | Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU6859a. CAS No. 127254-12-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0395. | |
| Sitafloxacin hydrate | Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic ( antibiotic ) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU6859a hydrate. CAS No. 163253-35-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0395C. | |
| Sitagliptin | Sitagliptin (MK-0431) is a potent and orally active inhibitor of DPP4 with an IC 50 of 19 nM in Caco-2 cell extracts [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0431. CAS No. 486460-32-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13749. | |
| Sitagliptin-d4 phosphate | Sitagliptin-d 4 (phosphate) is the deuterium labeled Sitagliptin phosphate. Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1432063-88-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-13749AS. | |
| Sitagliptin phosphate | Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor of DPP4 with an IC 50 of 19 nM in Caco-2 cell extracts [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0431 phosphate. CAS No. 654671-78-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13749A. | |
| Sitagliptin phosphate monohydrate | Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP4 with an IC 50 of 19 nM in Caco-2 cell extracts [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0431 phosphate monohydrate. CAS No. 654671-77-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13749B. | |
| Sitaxsentan sodium | Sitaxsentan sodium (IPI 1040 sodium; TBC11251 sodium) is an orally active, highly selective antagonist of endothelin A receptors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IPI 1040 sodium; TBC11251 sodium. CAS No. 210421-74-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-11103. | |
| Sitravatinib | Sitravatinib (MGCD516) is an orally bioavailable receptor tyrosine kinase (RTK) inhibitor with IC 50 s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively [1]. Sitravatinib shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGCD516; MG-516. CAS No. 1123837-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-16961. | |
| Sivifene | Sivifene (A-007) is a triaryl hydrazone. Sivifene has anticancer activity and immunomodulatory effects. Sivifene regulates immune regulation by upregulating CD45 T lymphocyte surface receptors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A-007. CAS No. 2675-35-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-14801. | |
| (+)-SJ733 | (+)-SJ733 is an anti-malaria agent which can also inhibit Na + -ATPase PfATP4. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SJ000557733. CAS No. 1424799-20-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19556. | |
| SJF-0628 | SJF-0628 (compound 512) is a PROTAC RAF degrader. SJF-0628 induces targeted degradation of BRAF mutants ( DC 50 : 5.4 nM, 4.64 nM, 15.5 nM, 2.11 nM, 63.9 nM for BRAF V600E, V600K, G464V, G469A, K601E respectively). SJF-0628 has anti-tumor activity. SJF-0628 can be used for research of disorders that result from aggregation or accumulation of RAF, or the constitutive activation of RAF [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2413035-41-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136420. | |
| SJF-1521 | SJF-1521 is a selective EGFR PROTAC degrader. SJF-1521 contains the EGFR inhibitor lapatinib (HY-50898). SJF-1521 can induce EGFR degradation in OVCAR8 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230821-40-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131865. | |
| SK609 hydrochloride | SK609 hydrochloride is a dopamine D3 receptor (D3R) selective agonist with an EC 50 of 1109 nM. SK609 hydrochloride has the potential for parkinson research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092797-77-7. Pack Sizes: 5 mg. Product ID: HY-117059. | |
| SKA-31 | SKA-31 is a potent potassium channel activator with EC 50s of 260 nM, 1.9 μM, 2.9 μM, and 2.9 μM for KCa3.1 , KCa2.2 , KCa2.1 and KCa2.3 , respectively. SKA-31 potentiates endothelium-derived hyperpolarizing factor response and lowers blood pressure [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 40172-65-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111655. | |
| Skatole | Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors ( AhR ) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Methylindole; 3-Methyl-1H-indole. CAS No. 83-34-1. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W007355. | |
| (S)-Ketorolac | (S)-Ketorolac is a nonsteroidal anti-inflammatory agent. (S)-ketorolac exhibits potent COX1 and COX2 enzyme inhibition [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Ketorolac. CAS No. 66635-92-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0580A. | |
| SKF 81297 | SKF 81297 is a potent and selective dopamine D1 receptor agonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71636-61-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12236A. | |
| SKF 81297 hydrobromide | SKF 81297 hydrobromide is a potent and selective dopamine D1 receptor agonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67287-39-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12236. | |
| SKF 83959 | SKF83959 is a potent and selective dopamine D 1 -like receptor partial agonist. SKF83959 K i values for rat D 1 , D 5 , D 2 and D 3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 is a potent allosteric modulator of sigma (σ)-1 receptor. SKF83959 belongs to benzazepine family and has improvements on cognitive dysfunction. SKF83959 can be used for the research of Alzheimer's disease and depression [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80751-85-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-130344. | |
| SKF 83959 hydrobromide | SKF83959 hydrobromide is a potent and selective dopamine D 1 -like receptor partial agonist. SKF83959 hydrobromide K i values for rat D 1 , D 5 , D 2 and D 3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 hydrobromide is a potent allosteric modulator of sigma (σ)-1 receptor. SKF83959 hydrobromide belongs to benzazepine family and has improvements on cognitive dysfunction. SKF83959 hydrobromide can be used for the research of Alzheimer's disease and depression [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67287-95-0. Pack Sizes: 5 mg. Product ID: HY-103412. | |
| SKF89976A hydrochloride | SKF89976A hydrochloride is a selective GABA transporter ( GAT-1 ) inhibitor with IC 50 s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: d,l-SKF89976A hydrochloride. CAS No. 85375-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100228A. | |
| SKF 91488 dihydrochloride | SKF 91488 (Homodimaprit) dihydrochloride is a potent and noncompetitive histamine N-methyltransferase inhibitor with a K i value of 0.9 microM. SKF 91488 dihydrochloride inhibits the methylation of labeled histamine in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Homodimaprit dihydrochloride. CAS No. 68941-21-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100967. | |
| SKF-96365 hydrochloride | SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca 2+ entry (SOCE) inhibitor. SKF-96365 hydrochloride significantly inhibits hERG, hKCNQ1/hKCNE1, hKir2.1 and hKv4.3 current, and significantly prolongs the QTc interval in isolated guinea pig hearts. SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130495-35-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100001. | |
| SKI-I | SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK) , with an IC 50 of 1.2 μM for ST-hSK. SKI-I also inhibits hERK2 ( IC 50 =11 μM). SKI-I induces apoptosis in tumor cell lines [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 306301-68-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115735. | |
| SKI II | SKI-II is an oral active and synthetic inhibitor of sphingosine kinase (SK) activity, with IC 50 values of 78 μM and 45 μM for SK1 and for SK2, respectively. SKI II causes an irreversible inhibition of SK1 by inducing its lysosomal and/or proteasomal degradation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312636-16-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13822. | |
| Skimmianine | Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity [1]. Uses: Scientific research. Group: Natural products. CAS No. 83-95-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2081. | |
| SKI V | SKI V is a noncompetitive and potent non-lipid sphingosine kinase (SPHK; SK) inhibitor with an IC 50 of 2 μM for GST-hSK. SKI V potently inhibits PI3K with an IC 50 of 6 μM for hPI3k. SKI V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P). SKI V induces apoptosis and has antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24418-86-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12895. | |
| Skyrin | Skyrin is an anthraquinone compound that can be isolated from almond fruit. Skyrin is a receptor-selective glucagon antagonist. Skyrin can inhibit the growth of tumor cells [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 602-06-2. Pack Sizes: 1 mg. Product ID: HY-119739. | |
| (S)-Lansoprazole | (S)-Lansoprazole (Levolansoprazole) is an isoform of Lansoprazole (HY-13662), which is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole (AG 1749) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Levolansoprazole. CAS No. 138530-95-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13662C. | |
| SLF | SLF is a synthetic ligand for FK506-binding protein (FKBP) with an affinity of 3.1 μM for FKBP51 and an IC 50 of 2.6 μM for FKBP12. SLF can be used in the synthesis of PROTAC [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 195513-96-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114872. | |
| SLF1081851 | SLF1081851 is a Spns2 inhibitor, inhibits S1P release ( IC 50 =1.93 μM). SLF1081851 plays a key role in development and immune system [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2763730-97-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149004. | |
| SLF TFA | SLF TFA is a synthetic ligand for FK506-binding protein (FKBP) with an affinity of 3.1 μM for FKBP51 and an IC 50 of 2.6 μM for FKBP12. SLF TFA can be used in the synthesis of PROTAC [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2378802-47-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114872A. | |
| SLM6031434 hydrochloride | SLM6031434 hydrochloride is a highly selective sphingosine kinase 2 (SphK2) inhibitor with K i s of 0.4 μM, 0.5 μM, >20 μM, 22 μM for mSphK2, rSphK2, mSphK1 and rSphK1, respectively. SLM6031434 hydrochloride decrease Sphingosine 1-phosphate (S1P) levels in U937 monocytic leukemia cells. SLM6031434 hydrochloride has the potential for renal fibrosis research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1897379-34-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-120268A. | |
| SLP7111228 hydrochloride | SLP7111228 (hydrochloride) is a biochemical reagent. Uses: Scientific research. Group: Signaling pathways. CAS No. 1449768-48-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-120152A. | |
| SLU-PP-332 | SLU-PP-332 is a pan- Estrogen Receptor/ERR agonist with EC 50 values of 98, 230 and 430 nM for ERRα , ERRβ and ERRγ , respectively. SLUPP-332 enhances mitochondrial function and cellular respiration in skeletal muscle cell lines. SLU-PP-332 has the potential to study metabolic diseases as well as improve muscle function [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 303760-60-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155673. | |
| (S)-LY-3381916 | (S)-LY-3381916 ((S)-IDO1-IN-5; Example 1B) is an active S-isomer of LY-3381916. (S)-LY-3381916 binds to IDOL with an IC 50 value less than 1.5 μΜ [1]. LY-3381916 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1 [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-IDO1-IN-5. CAS No. 2166616-76-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111540B. | |
| SM-102 | SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles ( LNPs ). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2089251-47-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134541. | |
| SM-164 | SM-164 is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains with an IC 50 value of 1.39 nM and functions as an extremely potent antagonist of XIAP. Uses: Scientific research. Group: Signaling pathways. CAS No. 957135-43-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15989. | |
| SM-164 hydrochloride | SM-164 hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains with an IC 50 value of 1.39 nM and functions as an extremely potent antagonist of XIAP. Uses: Scientific research. Group: Signaling pathways. CAS No. 2734174-02-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15989A. | |
| Sm4 | Sm4 is a SOX18 inhibitor. Sm4 shows SOX18-DNA binding inhibitory activity. Sm4 selectively affects SOX18 transcriptional output in vitro. Sm4 blocks SoxF transcriptional activity in vivo. Sm4 can be used for cancer metastasis and vascular cancers research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 365542-77-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116940. | |
| SM-433 | SM-433, a Smac mimetic, function as inhibitor of inhibitor of apoptosis proteins (IAPs). SM-433 exhibits strong binding affinity XIAP BIR3 protein with an IC 50 <1 μM (patent WO2008128171A2) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1071992-81-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-138059. | |
| (S)-Malic acid (Standard) | (S)-Malic acid (Standard) is the analytical standard of (S)-Malic acid. This product is intended for research and analytical applications. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive. In Vitro: It is showed that ME is essential for (S)-2-Hydroxysuccinic acid (L-malic acid) utilization in L. casei. Furthermore, deletion of either the gene encoding the histidine kinase or the response regulator of the TC system resulted in the loss of the ability to grow on (S)-2-Hydroxysuccinic acid, thus indicating that the cognate TC system regulates and is essential for the expression of ME. Transcriptional analyses shows that expression of maeE is induced in the presence of (S)-2-Hydroxysuccinic acid and repressed by glucose, whereas TC system expression is induced by (S)-2-Hydroxysuccinic acid and is not repressed by glucose [1]. Uses: Scientific research. Group: Natural products. CAS No. 97-67-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-Y1069R. | |
| (S)-Mandelic acid | (S)-Mandelic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 17199-29-0. Pack Sizes: 100 g. Product ID: HY-Y0816. | |
| SMANT hydrochloride | SMANT hydrochloride is a Smoothened ( Smo ) signaling inhibitor. SMANT hydrochloride is antagonist of Smo accumulation within the primary cilium (PC). SMANT hydrochloride has an equivalent activity in inhibiting SmoM2 (oncogenic form of Smo) and wild-type Smo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1177600-74-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108508. | |
| SMARCA2/4-IN-2 | SMARCA2/4-IN-2 is a PROTAC target protein ligand ( Ligands for Target Protein for PROTACs ). SMARCA2/4-IN-2 can be used for synthesis PROTAC SMARCA2/4-degrader-5 (HY-159456) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1339378-93-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163926. | |
| SMCC | SMCC is a protein crosslinker. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 64987-85-5. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 25 g; 100 g. Product ID: HY-42360. | |
| (S)-Mephenytoin | (S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsive agent. (S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. (S)-Mephenytoin can be used for the analysis of cytochrome P450 metabolism [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Mephenytoin. CAS No. 70989-04-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1184A. | |
| SMER28 | SMER28 is a positive regulator of autophagy acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide. Uses: Scientific research. Group: Signaling pathways. CAS No. 307538-42-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100200. | |
| S-Methoprene | S-Methoprene is an insect juvenile hormone analog and effective insecticide that blocks the transition from pupa to adult. S-Methoprene is also a CB(1) receptor ligand and inhibits the binding of the CB1 receptor antagonist [ 3 H]CP-55940 to the CB1 receptor ( IC 50 : 19.31 μM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Methoprene; (7S)-Methoprene. CAS No. 65733-16-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1161A. | |
| (S)-methyl 2-amino-3-cyclohexylpropanoate hydrochloride | (S)-methyl 2-amino-3-cyclohexylpropanoate hydrochloride is an alanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 17193-39-4. Pack Sizes: 10 g; 25 g. Product ID: HY-W007136. | |
| (S)-Methyl 2-oxooxazolidine-4-carboxylate | 4-Oxazolidinecarboxylic acid, 2-oxo-, methyl ester, (S)- is a biological molecule. Uses: Scientific research. Group: Signaling pathways. CAS No. 132682-22-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-Z0425. | |
| (S)-Methyl 3-amino-2-((tert-butoxycarbonyl)amino)propanoate hydrochloride | (S)-Methyl 3-amino-2-((tert-butoxycarbonyl)amino)propanoate hydrochloride is an alanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 181228-33-1. Pack Sizes: 250 mg; 1 g; 5 g. Product ID: HY-W006152. | |
| S-Methylglutathione | S-Methylglutathione is an S-substitued glutathione and a stronger nucleophile than GSH [1]. S-Methylglutathione has inhibitory effect on glyoxalase 1 [2]. Uses: Scientific research. Group: Peptides. CAS No. 2922-56-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-W009177. | |
| S-Methylisothiourea sulfate | S-Methylisothiourea sulfate is a potent, selective and competitive inhibitor of inducible nitric oxide synthase (iNOS). S-Methylisothiourea sulfate exerts beneficial effects in rodent models of septic shock [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 867-44-7. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-79457. | |
| S-Methyl-L-cysteine | S-Methyl-L-cysteine is a natural product that acts as a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA), with antioxidative, neuroprotective, and anti-obesity activities. Uses: Scientific research. Group: Natural products. Alternative Names: L-S-Methylcysteine. CAS No. 1187-84-4. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-B2188. | |
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