MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Selurampanel | Selurampanel (BGG 492) is an orally active and competitive AMPA receptor antagonist with an IC 50 of 190 nM. Selurampanel has reasonable blood-brain barrier penetration. Selurampanel can be used for epilepsy research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BGG 492. CAS No. 912574-69-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-105860. |  |
| Selvigaltin | Selvigaltin (GB1211) is an orally active galectin-3 small molecule inhibitor with an IC 50 value of 12 nM in rabbits, showing anti-tumor activity. Selvigaltin decreases galectin-3 levels in the liver and reduces biomarkers of liver function (AST, ALT, bilirubin), inflammation (cells foci) and fibrosis (PSR, SHG), as well as decreasing the mRNA and protein expression of several key inflammation and fibrosis biomarkers (IL6, TGFβ3, SNAI2, collagen). Selvigaltin restores T-cell activity and induces less tumors and metastasis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GB1211. CAS No. 1978336-95-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147041. | |
| Semagacestat | Semagacestat is a γ-secretase inhibitor, inhibits β-amyloid ( Aβ42 ), Aβ38 and Aβ40 with IC 50 s of 10.9, 12 and 12.1 nM, respectively; also inhibits Notch signaling with IC 50 of 14.1 nM. Semagacestat can be used for the research of alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY450139. CAS No. 425386-60-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10009. | |
| Semaglutide | Semaglutide, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide has the potential for type 2 diabetes treatment. Uses: Scientific research. Group: Peptides. CAS No. 910463-68-2. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-114118. | |
| Semaglutide acetate | Semaglutide acetate, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide acetate has the potential for type 2 diabetes treatment. Uses: Scientific research. Group: Peptides. CAS No. 1997361-85-9. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-114118B. | |
| Semax acetate | Semax acetate is a nootropic neuroprotective peptide. Semax acetate can be used in the research of brain stroke [1]. Uses: Scientific research. Group: Peptides. CAS No. 2828433-33-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1146A. | |
| SEMBL | SEMBL is a potent NF-κB inhibitor. SEMBL can inhibit NF-κB-DNA binding, and also inhibits NF-κB-dependent inflammatory cytokine secretions. SEMBL inhibits cancer cell migration and invasion via decreasing MMP expression. SEMBL can be used for researching anticancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1443448-82-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-124651. | |
| Se-Methylselenocysteine | Se-Methylselenocysteine, a precursor of Methylselenol, has potent cancer chemopreventive activity and anti-oxidant activity. Se-Methylselenocysteine is orally bioavailable, and induces apoptosis [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Methylselenocysteine; Se-Methylseleno-L-cysteine. CAS No. 26046-90-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114245. | |
| Semicarbazide hydrochloride | Semicarbazide hydrochloride is an orally active urea derivative. Semicarbazide hydrochloride binds to copper or iron in cells. Semicarbazide hydrochloride inhibits the activity of soluble semicarbazide sensitive amine oxidase ( SSAO ). Semicarbazide hydrochloride damages cartilage, blood vessels, ovaries, testicles, and thyroid follicles [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aminourea hydrochloride; Hydrazinecarboxamide hydrochloride. CAS No. 563-41-7. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-Y0470. | |
| Semorinemab | Semorinemab (RG 6100) is an anti- Tau humanized IgG4 monoclonal antibody, targets the N-terminal portion of the Tau protein (amino acid residues 6-23). Semorinemab binds with human Tau with a K d value of 3.8 nM. Semorinemab can be used for the research of Alzheimer's Disease [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RG 6100; RO7105705; MTAU-9937A. CAS No. 2159141-27-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99399. | |
| Semustine | Semustine is a DNA alkylator , binds to DNA, and acts as a cancer chemotherapeutic agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13909-09-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13747. | |
| Senaparib | Senaparib (IMP4297) is a highly potent, selective and orally active PARP1/2 inhibitor. Senaparib (IMP4297) exhibits strong antitumor activity in animal models [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IMP4297; JS109. CAS No. 1401682-78-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137450. | |
| Senecionine | Senecionine (Senecionan-11,16-dione, 12-hydroxy-) is a pyrrolizidine alkaloid could be isolated from Senecio vulgaris. Senecionine decreases the activities of glutathione S-transferase, aminopyrine demethylase and arylhydrocarbon hydroxylase (AHH) [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Senecionan-11,16-dione, 12-hydroxy-; Aureine; Senecionin. CAS No. 130-01-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2560. | |
| Senicapoc | Senicapoc (ICA-17043) is a potent and selective Gardos channel (Ca 2+ -activated K + channel; KCa3.1 ) blocker with an IC 50 of 11 nM. Senicapoc blocks Ca 2+ -induced rubidium flux from human RBCs with an IC 50 value of 11 nM and inhibits RBC dehydration with IC 50 of 30 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICA-17043. CAS No. 289656-45-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50694. | |
| Seniprutug | Seniprutug is an anti- TRBV9 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2484772-72-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990762. | |
| Sennoside A | Sennoside A is an anthraquinone glycoside found in senna ( Cassia angustifolia ). Sennoside A is an HIV-1 inhibitor (IC 50 =3.8 μM) that inhibits HIV-1 replication. Sennoside A also inhibits HIV-1 reverse transcriptase (RT)-related DNA polymerase (RDDP) and ribonuclease H (Ribonuclease H) with IC 50 s of 1.9 μM and 5.3 μM, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 81-27-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0365. | |
| Sennoside B | Sennoside B is a potent and orally active platelet-derived growth factor (PDGF) inhibitor. Sennoside B inhibits cell proliferation and the expression of phosphorylation of PDGFR-β, STAT-5, AKT and ERK induced by PDGF-BB. Sennoside B shows gastroprotective activities. Sennoside B has the potential for the research of gastritis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 128-57-4. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-N0366. | |
| SEP-363856 hydrochloride | SEP-363856 (SEP-856) hydrochloride, an orally active TAAR1 and 5-HT1A agonist and CNS active psychotropic agent with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects. SEP-363856 hydrochloride has the potential for the study of schizophrenia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SEP-856 hydrochloride. CAS No. 1310422-41-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136109. | |
| Sepantronium bromide | Sepantronium bromide (YM-155) is a survivin inhibitor with an IC 50 of 0.54 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YM-155. CAS No. 781661-94-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10194. | |
| (-)-(S)-Equol | (-)-(S)-Equol is a high affinity ligand for estrogen receptor β with a K i of 0.73 nM. Uses: Scientific research. Group: Natural products. CAS No. 531-95-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100583. | |
| Serabelisib | Serabelisib (MLN1117) is a selective p110α inhibitor with an IC 50 of 15 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN1117; INK1117; TAK-117. CAS No. 1268454-23-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12285. | |
| Seralutinib | Seralutinib (GB002) is an inhaled PDGFRα and PDGFRβ inhibitor. Seralutinib also targets to CSF1R and c-KIT with IC 50 s of 8 nM and 14 nM, respectively. Seralutinib (GB002) is used in the study for pulmonary arterial hypertension [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GB002; PK10571. CAS No. 1619931-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109190. | |
| Seratrodast | Seratrodast (AA 2414), an orally active antiasthmatic agent, is a thromboxane A2 receptor (TP) antagonist and ferroptosis inhibitor. Seratrodast reduces lipid ROS production, modulates the systemic xc-/GSH/GPX4 axis, and inhibits JNK phosphorylation and p53 expression. Seratrodast exhibits anti-asthmatic and anti-epileptic activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AA 2414. CAS No. 112665-43-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0774. | |
| Sergliflozin etabonate | Sergliflozin etabonate (GW-869682X) is a potent and orally active sodium glucose cotransporter (SGLT2) inhibitor. Sergliflozin etabonate shows antidiabetic and antihyperglycemic effects. Sergliflozin etabonate significantly reduces non-fasting blood glucose levels in diabetic mice. Sergliflozin etabonate has the potential for the research of diabetes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW-869682X. CAS No. 408504-26-7. Pack Sizes: 10 mM * 1 mL; 1 mg. Product ID: HY-12611. | |
| Seribantumab | Seribantumab (MM 121) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SAR 256212; MM 121; Anti-Human ERBB3/ErbB 3 Recombinant Antibody. CAS No. 1334296-12-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99268. | |
| Serotonin | Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase ( COMT ) inhibitor with a K i of 44 μM. Uses: Scientific research. Group: Natural products. Alternative Names: 5-Hydroxytryptamine; 5-HT. CAS No. 50-67-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1473A. | |
| Serotonin hydrochloride | Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase ( COMT ) inhibitor with a K i of 44 μM. Uses: Scientific research. Group: Natural products. Alternative Names: 5-Hydroxytryptamine hydrochloride; 5-HT hydrochloride. CAS No. 153-98-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-B1473. | |
| Serplulimab | Serplulimab (HLX 10) is humanized monoclonal anti- PD-1 antibody. Serplulimab can be used in research of small cell lung cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HLX 10. CAS No. 2231029-82-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99118. | |
| Sertaconazole nitrate | Sertaconazole nitrate (FI7056) is a broad-spectrum topical antifungal agent, exhibits anti-inflammatory activity via activation of a p38-COX-2-PGE2 pathway. Sertaconazole nitrate is also a microtubule inhibitor, shows antiproliferative effect, induces apoptosis and autophagy , and can also inhibit the migration of cells [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FI7056. CAS No. 99592-39-9. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0736A. | |
| Sertindole | Sertindole (Lu 23-174) is an orally active 5-HT 2A , 5-HT 2C , dopamine D 2 , and αl-adrenergic receptors antagonist. Sertindole shows antipsychotic activity and anti-proliferative activity to multiple cancer cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu 23-174. CAS No. 106516-24-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14543. | |
| Sertraline hydrochloride | Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Sertraline hydrochloride is researched for a number of diseases, such as major depressive disorder and obsessive [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79559-97-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0176A. | |
| Serum thymic factor acetate | Serum thymic factor acetate (Thymulin acetate) is the acetate salt form of Serum thymic factor (HY-P3206). Serum thymic factor acetate is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor acetate stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor acetate protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor acetate exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor acetate can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Peptides. Alternative Names: Thymulin acetate; Thymic factor acetate. CAS No. 125117-65-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3206A. | |
| Sesamin | Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 607-80-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0121. | |
| (-)-Sesamin | (-)-Sesamin isolated from Asarum forbesii Maxim, is an isomer of Sesamin. Sesamin is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 13079-95-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0121A. | |
| Sesamol | Sesamol is a constituent of sesame oil. Sesamol shows a free radical scavenging activity. Sesamol shows an IC 50 =5.95±0.56 μg/mL in the DPPH assay. Anti-oxidant activities [1]. Anticancer activities [2]. Uses: Scientific research. Group: Natural products. CAS No. 533-31-3. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-N1417. | |
| Sesamolin | Sesamolin, isolated from Sesamum indicum , has antioxidative activity, Sesamolin inhibits lipid peroxidation and shows neuroprotection effect. Sesamolinl potently inhibits MAPK cascades by preventing phosphorylation of JNK , p38 MAPKs , and caspase-3 but not ERK-MAPK expression [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 526-07-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0809. | |
| SET2 | SET2 is a selective TRPV2 antagonist ( IC 50 =0.46 μM). SET2 blocks the TRP channel and suppresses prostate cancer cells migration. SET2 reduces the lysophosphatidic acid (LPA, a TRPV2 activator)-induced cytoplasmic calcium increases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2313525-20-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132222. | |
| Setanaxib | Setanaxib (GKT137831) is a selective NADPH oxidase ( NOX1/4 ) inhibitor with K i s of 140 and 110 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GKT137831; GKT831. CAS No. 1218942-37-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12298. | |
| Sethoxydim | Sethoxydim is a postemergent herbicide. Sethoxydim inhibits plant acetyl-coenzyme A carboxylase ( ACCase ) activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAS 9052. CAS No. 74051-80-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-135753. | |
| (S)-Ethyl 2-amino-4-fluoro-4-methylpentanoate sulfate | (S)-Ethyl 2-amino-4-fluoro-4-methylpentanoate sulfate is a leucine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 848949-85-9. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-77026. | |
| Setipiprant | Setipiprant (ACT-129968) is an orally active and selective CRTH2 antagonist. Setipiprant interacts with hCRTH2 receptor with an IC 50 value of 6 nM. Setipiprant inhibits prostanoid receptors h DP 1 and h EP 2 with IC 50 values of 1290 and 2600 nM, respectively. Setipiprant can be used for the research of asthma and rhinitis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-129968; KYTH-105. CAS No. 866460-33-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16635. | |
| Setiptiline | Setiptiline (Org-8282) is a serotonin receptor antagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Org-8282. CAS No. 57262-94-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-32329. | |
| Setiptiline maleate | Setiptiline maleate (MO-8282 maleate) is a serotonin receptor antagonist. Setiptiline maleate is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline maleate acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT 2A , 5-HT 2C , and/or 5-HT 3 subtypes, as well as an H1 receptor inverse agonist/antihistamine [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MO-8282. CAS No. 85650-57-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-32329A. | |
| Setmelanotide | Setmelanotide (RM-493) is a selective melanocortin 4 receptor ( MC4R ) agonist with EC 50 s of 0.27 nM and 0.28 nM for human and rat MC4R, respectively [1]. Uses: Scientific research. Group: Peptides. Alternative Names: RM-493; BIM-22493; IRC-022493. CAS No. 920014-72-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19870. | |
| (S)-(+)-Etomoxir | (S)-(+)-Etomoxir is the S enantiomer of Etomoxir (HY-50202). Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a ( CPT-1a ), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 828934-40-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W420033. | |
| Setrusumab | Setrusumab (BPS 804) is a fully human monoclonal antibody targets sclerostin. Setrusumab efftively improves bone strength. Setrusumab can be used for the resesrch of Osteogenesis Imperfecta (OI) and cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BPS 804. CAS No. 1847394-95-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99398. | |
| Sevasemten | Sevasemten is an orally active allosteric inhibitor of skeletal muscle myosin that protects skeletal muscle from contraction-induced injury. Sevasemten exhibits selectively myosin inhibition with IC 50 s of ≤10 μM (skeletal), >100 μM (cardiac), respectively. Sevasemten decreases muscle damage biomarkers and fibrosis while increasing muscle strength and activity in in Duchenne muscular dystrophy disease models [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2417395-15-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148799. | |
| Sevelamer carbonate | Sevelamer carbonate is an orally active and non-calcium-based phosphate binding agent and used for the hyperphosphatemia of chronic kidney disease (CKD)research. Sevelamer carbonate effectively lowers serum phosphorus levels hile having minimal effect on serum calcium or serum chloride levels in vivo. Sevelamer carbonate is considered as an improved, buffered form of sevelamer (HY-13995) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 845273-93-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-13995B. | |
| Sevelamer hydrochloride | Sevelamer hydrochloride is an orally active and phosphate binding agent used for research of hyperphosphatemia with chronic kidney disease. Sevelamer hydrochloride consists of polyallylamine that is crosslinked with epichlorohydrin [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 152751-57-0. Pack Sizes: 100 mg; 500 mg. Product ID: HY-13995A. | |
| Seviteronel | Seviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC 50 =69 nM) and an AR antagonist. Seviteronel demonstrates both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VT-464. CAS No. 1610537-15-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15996. | |
| Seviteronel racemate | Seviteronel racemate (VT-464 racemate) is the racemate form of Seviteronel (VT-464), which is a potent CYP17 lyase inhibitor(h-Lyase IC 50 =nM)inhibition. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VT-464 (racemate). CAS No. 1375603-36-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15996B. | |
| SEW?2871 | SEW2871 is an orally active, potent, highly selective S1P1 (sphingosine-1-phosphate type 1 receptor) agonist, with an EC 50 of 13.8 nM. SEW2871 activates ERK , Akt , and Rac signaling pathways and induces S1P1 internalization and recycling. SEW2871 reduces lymphocyte numbers in blood. SEW2871 can be used for the research of diabetes, Alzheimers disease, liver fibrosis, and inflammatory responses [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 256414-75-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-W008947. | |
| SF 11 | SF 11 is a potent and brain penetrant neuropeptide Y Y2 receptor antagonist ( IC 50 =199 nM). Antidepressant-like activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 443292-81-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107731. | |
| SF-22 | SF-22 is a potent and brain-penetrant antagonist of neuropeptide Y receptor (Y2R), with the IC 50 value of 750 nM. SF-22 plays an important role in neurological disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 824981-55-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132240. | |
| SF5 | SF5 (2,2-Diphenylethyl isothiocyanate) is a sulforaphane analog. SF5 inhibits apoptosis by the JNK-p53-caspase pathway. SF5 can be used as a new renal protective agent for drug-resistant acute renal disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,2-Diphenylethyl isothiocyanate. CAS No. 34634-22-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116794. | |
| (S)-Fluoxetine hydrochloride | (S)-Fluoxetine hydrochloride, an antidepressant, is serotonin reuptake inhibitor (SSRI) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 114247-06-2. Pack Sizes: 1 mg. Product ID: HY-B0102B. | |
| (S)-Flurbiprofen | (S)-Flurbiprofen is an active enantiomer of Flurbiprofen, with IC 50 values of 0.48 μM and 0.47 μM for COX-1 and COX-2 , respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Esflurbiprofen. CAS No. 51543-39-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-15123. | |
| SGC0946 | SGC0946 is a selective DOT1L H3K79 methyltransferase ) inhibitor, with an IC 50 of 0.3 nM. SGC0946 results in G1 arrest, inhibits potential of cell self-renewal and metastatic, also induces cell differentiation. SGC0946 can be used in studies of leukemia and solid tumors and also serve as a probe to further investigate the cellular mechanism of DOT1L in both normal and diseased cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1561178-17-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-15650. | |
| SGC2085 | SGC2085 is a potent and selective inhibitor of coactivator associated arginine methyltransferase 1 ( CARM1 ) with an IC 50 of 50 nM. SGC2085 also selectively inhibits PRMT6 with an IC 50 value of 5.2 μM, but not other PRMT proteins [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1821908-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100565. | |
| SGC-AAK1-1 | SGC-AAK1-1 is a potent and selective AAK1 (AP2 associated kinase 1) inhibitor with an IC 50 of 270 nM and a K i of 9 nM. SGC-AAK1-1 also potently inhibits BMP2K. SGC-AAK1-1 is used to study Wnt pathway related to AAK1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2247894-32-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123940. | |
| SGC-CK2-1 | SGC-CK2-1 is a highly potent, ATP-competitive, and cell-active CK2 chemical probe with exclusive selectivity for both human CK2 isoforms, with IC 50 s of 36 and 16 nM for CK2α and CK2αrespectively in the nanoBRET assay. SGC-CK2-1 can be used for the research of neurodegenerative diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2470424-39-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139004. | |
| SGC-STK17B-1 | SGC-STK17B-1 is an ATP-competitive and selective STK17B (a member of DAPK family) inhibitor ( IC 50 : 34 nM, K D : 5.6 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2650530-00-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-156350. | |
| SGI-1776 free base | SGI-1776 free base is an inhibitor of Pim kinases, with IC 50 s of 7 nM, 363 nM, and 69 nM for Pim-1, -2 and -3, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1025065-69-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13287. | |
| SGLT2-IN-1 | SGLT2-IN-1 (Compound 5) is an inhibitor for sodium-dependent glucose cotransporter ( SGLT2 ), with IC 50 of 33 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 864070-37-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-I1120. | |
| (S)-Gossypol (acetic acid) | (S)-Gossypol is the isomer of a natural product Gossypol. (S)-Gossypol binds to the BH3-binding groove of Bcl-xL and Bcl-2 proteins with high affinity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-(+)-Gossypol acetic acid. CAS No. 1189561-66-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15464D. | |
| SGR-1505 | SGR-1505 is an orally active MALT1 allosteric inhibitor. SGR-1505 inhibits MALT1 enzymatic activity and shows anti-proliferative activity in BTK inhibitor (BTKi)-sensitive and BTKi-resistant activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL) cell lines. SGR-1505 can be used for research of B-cell lymphomas [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2661481-41-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160698. | |
| Shanzhiside methyl ester | Shanzhiside methy lester is isolated from lamiophlomis rotata. Shanzhiside methyl ester is a small molecule glucagon-like peptide-1 (GLP-1) receptor agonist and has the ability to induce anti-allodynic tolerance [1]. Uses: Scientific research. Group: Natural products. CAS No. 64421-28-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0630. | |
| S-Hexylglutathione | S-Hexylglutathione is an S-substituted glutathione in which the hydrogen of the thiol has been replaced by a hexyl group. S-Hexylglutathione is also an competitive inhibitor against glutathione-S-transferase. S-Hexylglutathione can be used as an affinity chromatographic ligand for glutathione-S-transferase and glutathione peroxidase [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24425-56-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W013754. | |
| (S)-Higenamine hydrobromide | (S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-Norcoclaurine hydrobromide. CAS No. 105990-27-0. Pack Sizes: 1 mg. Product ID: HY-N2037C. | |
| Shikimic acid | Shikimic acid is a key metabolic intermediate of the aromatic amino acid biosynthesis pathway, found in microbes and plants. Uses: Scientific research. Group: Natural products. CAS No. 138-59-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0130. | |
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