MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Scoparone | Scoparone is isolated from Artemisia capillaris Thunb., has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 120-08-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0228. |  |
| Scopine | Scopine is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock. Uses: Scientific research. Group: Natural products. Alternative Names: 6,7-Epoxytropine. CAS No. 498-45-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0459. | |
| Scopine hydrochloride | Scopine hydrochloride (6,7-Epoxytropine hydrochloride) is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 6,7-Epoxytropine hydrochloride. CAS No. 85700-55-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0459A. | |
| Scopolamine butylbromide | Scopolamine butylbromide is a competitive antagonist of muscarinic acetylcholine receptor (mAChR) with an IC50 of 55. Uses: Scientific research. Group: Natural products. Alternative Names: Hyoscine butylbromide; (-)-Scopolamine butylbromide; Butylscopolamine bromide. CAS No. 149-64-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0340. | |
| Scopolamine-d3 hydrobromide | Scopolamine-d 3 (hydrobromide) is the deuterium labeled Scopolamine hydrobromide[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Hyoscine-d3 hydrobromide. CAS No. 1279037-70-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W010892S. | |
| Scopolamine hydrobromide trihydrate | Scopolamine hydrobromide trihydrate (Hyoscine hydrobromide trihydrate) is used in ophthalmic preparations and has the potential for transdermal patches of motion sickness [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Hyoscine hydrobromide trihydrate. CAS No. 6533-68-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W010892. | |
| Scopolamine nitrate | Scopolamine (nitrate) is an organic compound commonly used in neuroscience research and pharmacology research. It can be used to study the role and structure of acetylcholine receptors, and is widely used in drug development and research in related fields. In addition, this compound is also used as a substrate or catalyst in certain biochemical reactions. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Methscopolamine nitrate. CAS No. 6106-46-3. Pack Sizes: 25 mg; 50 mg. Product ID: HY-W127702. | |
| Scopoletin | Scopoletin is an inhibitor of acetylcholinesterase ( AChE ). Uses: Scientific research. Group: Natural products. Alternative Names: Gelseminic acid; Chrysatropic acid. CAS No. 92-61-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-N0342. | |
| Scopolin | Scopolin is a coumarin isolated from Arabidopsis thaliana (Arabidopsis) roots [1]. Scopolin attenuated hepatic steatosis through activation of SIRT1 -mediated signaling cascades [2]. Uses: Scientific research. Group: Natural products. CAS No. 531-44-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0341. | |
| Scopoline | Scopoline (compound 3a) is a compound formed from Scopine (HY-B0459), an α1 adrenergic receptor agonist [1]. Uses: Scientific research. Group: Natural products. CAS No. 487-27-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-122440. | |
| Scoulerine | Scoulerine ((-)-Scoulerine), an isoquinoline alkaloid, is a potent antimitotic compound. Scoulerine is also an inhibitor of BACE1 ( -site amyloid precursor protein cleaving enzyme 1). Scoulerine inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Scoulerine; Discretamine. CAS No. 6451-73-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N1255. | |
| Scriptaid | Scriptaid is a potent histone deacetylase (HDAC) inhibitor, used in cancer research. Scriptaid is also a sensitizer to antivirals and has potential for epstein-barr virus (EBV)-associated lymphomas treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Scriptide; GCK1026. CAS No. 287383-59-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15489. | |
| (S)-Crizotinib | (S)-Crizotinib is a potent and selective MTH1 (mutT homologue) inhibitor with an IC 50 of 330 nM. (S)-Crizotinib disrupts nucleotide pool homeostasis via MTH1 inhibition, induces an increase in DNA single strand breaks, activates DNA repair in human colon carcinoma cells, and effectively suppresses tumour growth in animal models [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1374356-45-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100549. | |
| SCS | SCS (Salicylidene salicylhydrazide) is a potent, allosteric and selective inhibitor of β1-containing GABA A receptors with an IC 50 of 32 nM against α2β1γ1θ by VIPR measurement. SCS is also a chelator of metal ions [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Salicylidene salicylhydrazide. CAS No. 3232-36-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103528. | |
| Scutellarein | Scutellarein is a natural flavonoid compound with anti-inflammatory effects. Uses: Scientific research. Group: Natural products. Alternative Names: 6-Hydroxyapigenin; 4',5,6,7-Tetrahydroxyflavone. CAS No. 529-53-3. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0752. | |
| Scutellarin | Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB , HIV-1(74V) and HIV-1KM018 with EC 50 s of 26 μM, 253 μM and 136 μM, respectively. Uses: Scientific research. Group: Natural products. CAS No. 27740-01-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0751. | |
| Scyllo-Inositol | Scyllo-Inositol, an amyloid inhibitor, potentialy inhibits α-synuclein aggregation. Scyllo-Inositol stabilizes a non-fibrillar non-toxic form of amyloid-β peptide (Aβ42) in vitro, reverses cognitive deficits, and reduces synaptic toxicity and lowers amyloid plaques in an Alzheimer's disease mouse model [1]. Uses: Scientific research. Group: Natural products. CAS No. 488-59-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W010041. | |
| Scytonemin | Scytonemin is a hydrophobic alkaloid pigment that can be isolated from the outer sheath of cyanobacteria. Scytonemin has protective function against short-wave solar ultraviolet (UV) radiation, which can reduce the generation of reactive oxygen species (ROS) and the formation of DNA damage. Scytonemin also has anti-inflammatory and anti-proliferative activities, produces concentration-dependent inhibition (IC 50 =2.0 μM) of polo-like kinase 1 ( PLK1 )-mediated cdc25C phosphorylation, and plays an important role in regulating the G2/M transition in the cell cycle. It can be used in the research of cancer, acute inflammation and sunscreen cosmetics [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 152075-98-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112356. | |
| SD-1008 | SD-1008 is a potent JAK inhibitor. SD-1008 inhibits tyrosyl phosphorylation of STAT3, JAK2 and Src. SD-1008 also reduces STAT3-dependent luciferase activity. SD-1008 enhances apoptosis induced by Paclitaxel in ovarian cancer cells via directly blocking the JAK-STAT3 signaling pathway [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 960201-81-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107595. | |
| SD-208 | SD-208 is a selective TGF-βRI (ALK5) inhibitor with IC 50 of 48 nM, and > 100-fold selectivity over TGF-βRII. Uses: Scientific research. Group: Signaling pathways. CAS No. 627536-09-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13227. | |
| SD-6 | SD-6 is an orally active inhibitor of hAChE and hBChE with IC 50 values of 0.907 μM and 1.579 μM, respectively. SD-6 has excellent blood-brain barrier (BBB) permeability and no neurotoxicity, which can be used for research on Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 744206-31-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149212. | |
| SD-70 | SD-70 is an inhibitor for histone demethylase JMJD2C and exhibits antitumor efficacy. SD-70 inhibits viability of cancer cells CWR22Rv1 (9% cell survival at 10 μM), PC3 (14% cell survival at 2 μM) and DU145 (26% cell survival at 2 μM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 332173-89-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121522. | |
| S-Diclofenac | S-Diclofenac is a hybrid molecule of an H 2 S donor and the NSAID diclofenac. S-Diclofenac spares the gastric mucosa of injury despite markedly suppressing prostaglandin synthesis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACS 15; ATB-337. CAS No. 912758-00-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15035. | |
| (S)-(+)-Dimethindene maleate | (S)-(+)-Dimethindene maleate, an enantiomer, is a potent M 2 -selective muscarinic receptor antagonist ( pA 2 = 7.86/7.74; pK i = 7.78). (S)-(+)-Dimethindene maleate shows lower affinities for the muscarinic M 1 (pA 2 = 6.83/6.36; pK i = 7.08), the M 3 (pA 2 = 6.92/6.96; pK i = 6.70) and the M 4 receptors (pK i = 7.00), respectively. (S)-(+)-Dimethindene maleate also is a histamine H 1 receptor antagonist ( pA 2 = 7.48) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 136152-65-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107647. | |
| SDMA | SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide ( NO ) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing. Uses: Scientific research. Group: Natural products. Alternative Names: Symmetric dimethylarginine; NG,NG'-Dimethyl-L-arginine. CAS No. 30344-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101410. | |
| (S)-Donepezil | (S)-Donepezil is a S-enantiomer of Donepezil (HY-14566). Donepezil is a specific and potent AChE inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-E2020 free base. CAS No. 142057-80-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14566A. | |
| SDZ 220-581 | SDZ 220-581 is an orally active, potent, competitive NMDA receptor antagonist with pK i value of 7.7 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 174575-17-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13059. | |
| SDZ 220-581 hydrochloride | SDZ 220-581 hydrochloride is an orally active, potent, competitive NMDA receptor antagonist with pK i value of 7.7 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179411-93-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13059B. | |
| Sebetralstat | Sebetralstat (KVD900) is a plasma kallikrein inhibitor (WO2016083820). Sebetralstat can be used for the research of metabolic diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KVD900. CAS No. 1933514-13-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132830. | |
| SEC | SEC induces activation of ANXA7 GTPase via the AMPK/mTORC1/STAT3 signaling pathway. SEC selectively promotes apoptosis in cancer cells, expressing a high level of ITGB4 by inducing ITGB4 nuclear translocation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1802997-81-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125355. | |
| SecinH3 | SecinH3 is an antagonist of cytohesins with IC 50 s of 5.4 μM, 2.4 μM, 5.4 μM, 5.6 μM, 5.6 μM and 65 μM for hCyh1 , hCyh2 , mCyh3 , hCyh3 , drosophila steppke and yGea2-S7 , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 853625-60-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-100559. | |
| Seclidemstat | Seclidemstat is a potent noncompetitive and reversible KDM1A (LSD1) inhibitor ( K i =31 nM, IC 50 =13 nM). Seclidemstat promotes antitumor immunity in switch/sucrose nonfermentable (SWI/SNF) complex mutated ovarian cancer, as well as inhibit virus production, viral DNA replication, and late gene expression. Seclidemstat can be used for the research of Ewing Sarcoma [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SP-2577. CAS No. 1423715-37-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103713. | |
| Seclidemstat mesylate | Seclidemstat (SP-2577) mesylate is a potent noncompetitive and reversible KDM1A (LSD1) inhibitor ( K i =31 nM, IC 50 =13 nM). Seclidemstat mesylate promotes antitumor immunity in switch/sucrose nonfermentable (SWI/SNF) complex mutated ovarian cancer, as well as inhibit virus production, viral DNA replication, and late gene expression. Seclidemstat mesylate can be used for the research of Ewing Sarcoma [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SP-2577 mesylate. CAS No. 2044953-70-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103713A. | |
| Secnidazole | Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP-14539; PM-185184. CAS No. 3366-95-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B1118. | |
| Secoisolariciresinol | Secoisolariciresinol is a lignan, a type of phenylpropanoids. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Secoisolariciresinol. CAS No. 29388-59-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N6071. | |
| (+)-Secoisolariciresinol | (+)-Secoisolariciresinol, a lignan compound, is a (+)-enantiomer of Secoisolariciresinol [1]. Uses: Scientific research. Group: Natural products. CAS No. 145265-02-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8172. | |
| Secoisolariciresinol diglucoside | Secoisolariciresinol diglucoside ((S,S)-SDG), the main lignan in wholegrain flaxseed, is known for its beneficial effects including anti-inflammatory, antioxidant, anti-mutagenic, anti-microbial, anti-obesity, hypolipidemic, and neuroprotective effects [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (S,S)-SDG; (S,S)-LGM2605. CAS No. 257930-74-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105008. | |
| Secologanin | Secologanin, a secoiridoid glucoside, is a pivotal terpenoid intermediate in the biosynthesis of biologically active monoterpenoid indole alkaloids such as reserpine, ajmaline, and vinblastine. Secologanin synthase (cytochrome P450 isoform CYP72A1) catalyzes the oxidative cleavage of loganin into Secologanin [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 19351-63-4. Pack Sizes: 1 mg. Product ID: HY-125598. | |
| Secoxyloganin | Secoxyloganin, isolated from Lonicera japonica Thunb, inhibits the blood flow (BF) decrease. Secoxyloganin has allergy-preventive activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 58822-47-2. Pack Sizes: 5 mg; 10 mg; 20 mg. Product ID: HY-N3009. | |
| Secretin (swine) | Secretin (swine), a neuroendocrine hormone , is the first hormone to be identifie and is secreted by S cells that are localized primarily in the mucosa of the duodenum. Secretin also is a 27-amino acid peptide, which acts on secretin receptors. Secretin is expressed by cells in all mature enteroendocrine cell subsets and can be prompted by fatty acids. Secretin stimulates the secretion of pancreatic water and bicarbonate. Secretin exerts various effects in organs, can be used for the research of digestive system, central nervous system and energy metabolism [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 17034-35-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-109538. | |
| Secukinumab | Secukinumab (AIN457) is a high affinity, human monoclonal antibody targeted against interleukin (IL)-17A. Secukinumab is the first-in-class anti-IL-17 agent used for the research of plaque psoriasis, ankylosing spondylitis and psoriatic arthritis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AIN457. CAS No. 1229022-83-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9927. | |
| Secukinumab (Anti-Human IL-17A) | Secukinumab (Anti-Human IL-17A) is a fully human anti- interleukin-17A monoclonal antibody. Anti-Human IL-17A can be used for research in psoriasis pathogenesis [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1229022-83-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9927A. | |
| (-)-Securinine | (-)-Securinine is plant-derived alkaloid and also a GABA A receptor antagonist. Uses: Scientific research. Group: Natural products. CAS No. 5610-40-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N2079. | |
| Sedanolide | Sedanolide, a natural compound occurring in edible umbelliferous plants, possesses anti-inflammatory and antioxidant activities [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 6415-59-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2114. | |
| S-EIT hydrobromide | S-EIT (hydrobromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: S-Ethylisothiourea hydrobromide. CAS No. 1071-37-0. Pack Sizes: 25 g. Product ID: HY-101252. | |
| SEL120-34A hydrochloride | SEL120-34A hydrochloride is a potent, selective, orally available, ATP-competitive CDK8 inhibitor, with IC 50 s of 4.4 nM and 10.4 nM for CDK8/CycC and CDK19/CycC, respectively, with antitumor activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 1609452-30-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-111388B. | |
| Seladelpar | Seladelpar (MBX-8025) is an orally active, potent and specific PPARδ agonist with an EC 50 of 2 nM. Seladelpar shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar can be used for the study of primary biliary cholangitis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MBX-8025; RWJ-800025. CAS No. 851528-79-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19522. | |
| Seladelpar (lysine) | Seladelpar (MBX-8025) lysine is an orally active, potent and specific PPARδ agonist with an EC 50 of 2 nM. Seladelpar lysine shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar lysine can be used for the study of primary biliary cholangitis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MBX-8025 (lysine). CAS No. 928821-41-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-19522B. | |
| Seladelpar Lysine dihydrate | Seladelpar (MBX-8025) Lysine dihydrate is the Lysine dihydrate salt form of Seladelpar (HY-19522). Seladelpar Lysine dihydrate is an orally active agonist for potent PPAR-δ , with EC 50 of 2 nM. Seladelpar Lysine dihydrate shows more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively. Seladelpar Lysine dihydrate can be used for the study of primary biliary cholangitis. Seladelpar Lysine dihydrate normalizes hyperglycemia, hyperinsulinemia, glucose, serum lipids and cholesterol levels, ameliorates the nonalcoholic steatohepatitis in mouse model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MBX-8025 Lysine dihydrate; RWJ-800025 Lysine dihydrate. CAS No. 928821-40-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-19522C. | |
| Selamectin | Selamectin, a semi-synthetic macrocyclic lactone, is a potent parasiticide and anthelminthic. Selamectin activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent heartworm , Lymphatic filariae , and nematode infection. Selamectin is also a potent P-glycoprotein substrate and a P-glycoprotein inhibitor with an IC 50 of 120 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 220119-17-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107212. | |
| Selatogrel | Selatogrel (ACT-246475) is a reversible and selective P2Y 12 receptor antagonist which inhibits platelet aggregation with an IC 50 of 8 nM. Selatogrel exhibits antithrombotic efficacy [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-246475. CAS No. 1159500-34-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109122. | |
| Selegiline hydrochloride | Selegiline (Deprenyl) hydrochloride is a potent, selective and irreversible inhibitor of MAO-B , with an IC 50 of 51 nM. Selegiline hydrochloride exhibits 450-flod selectivity for MAO-B over MAO-A (IC 50 =23 μM). Selegiline hydrochloride can be used for the research of Parkinson's disease, Alzheimer's disease and major depressive disorder [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Deprenyl hydrochloride; (-)-Selegiline hydrochloride; (-)-Deprenyl hydrochloride. CAS No. 14611-52-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-14199. | |
| Selenocystine | Selenocystine is a broad-spectrum anti-cancer agent. Selenocystine induces DNA damage in HepG2 cells, particularly in the form of DNA double strand breaks (DSBs). Selenocystine exhibits great promise as a therapeutic or adjuvant agent targeting DNA repair for cancer treatment [1]. Uses: Scientific research. Group: Peptides. CAS No. 2897-21-4. Pack Sizes: 10 mg; 25 mg. Product ID: HY-113064. | |
| Selenomethionine | Selenomethionine is a naturally occurring amino acid containing selenium that has oral activity and is a common natural food source. Selenomethionine has antitumor activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Seleno-DL-methionine; DL-Selenomethionine. CAS No. 1464-42-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B1000. | |
| Selepressin | Selepressin (FE 202158) is a selective vasopressin V 1A receptor agonist. Selepressin is a potent vasopressor. Selepressin can be used in the research of septic shock [1] [2] [4]. Uses: Scientific research. Group: Peptides. Alternative Names: FE 202158. CAS No. 876296-47-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-105239. | |
| Seletracetam | Seletracetam (Ucb 44212), as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ucb 44212. CAS No. 357336-74-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119810. | |
| Selexipag | Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin ( PGI 2 ) receptor (IP receptor). Uses: Scientific research. Group: Signaling pathways. Alternative Names: NS-304; ACT-293987. CAS No. 475086-01-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14870. | |
| Selfotel | Selfotel (CGS 19755) is a selective and competitive antagonist at N-methyl-D-aspartate (NMDA) -preferring receptor. CGS 19755 inhibits the binding of [3H]-3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid to NMDA-type receptors with an IC 50 of 50 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGS 19755. CAS No. 110347-85-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-15086. | |
| Selicrelumab | Selicrelumab is an agonist CD40 antibody, induces changes in the tumor microenvironment. Selicrelumab can be used for the research of pancreatic cance and neoadjuvant study [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1622140-49-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99046. | |
| Seliforant | Seliforant (SENS-111) is a selective and orally histamine H4 receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SENS-111. CAS No. 1164115-89-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109074. | |
| Selinexor | Selinexor (KPT-330), analog of KPT-185, is an orally bioavailable and selective CRM1 inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KPT-330. CAS No. 1393477-72-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17536. | |
| Selisistat | Selisistat (EX-527) is a potent and selective SirT1 (Sir2 in Drosophila melanogaster) inhibitor with an IC 50 of 123 nM for SirT1. Selisistat alleviates pathology in multiple animal and cell models of Huntington's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EX-527. CAS No. 49843-98-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15452. | |
| Selitrectinib | Selitrectinib (LOXO-195) is a next-generation TRK kinase inhibitor, with IC 50 s of 0.6 nM and <2.5 nM for TRKA and TRKC , respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LOXO-195. CAS No. 2097002-61-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101977. | |
| Selonsertib | Selonsertib (GS-4997), an orally bioavailable, selective apoptosis signal-regulating kinase 1 ( ASK1 ) inhibitor with a pIC 50 of 8.3, has been evaluated as an experimental treatment for diabetic nephropathy and kidney fibrosis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-4997. CAS No. 1448428-04-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-18938. | |
| Selpercatinib | Selpercatinib (LOXO-292) is a potent, selective RET kinase inhibitor with IC 50 values of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M), and RET (G810R), respectively. Selpercatinib has anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LOXO-292. CAS No. 2152628-33-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114370. | |
| SelSA | SelSA is a selective, orally active inhibitor for histone deacetylase 6 ( HDAC6 ) with IC 50 of 56.9 nM. SelSA inhibits the phosphorylation of ERK1/2. SelSA inhibits the proliferation of breast cancer cells and hepatocellular carcinoma cells with IC 50 of 0.58-2.6 μM, inhibits cell migration and invasion of Huh7, and induces apoptosis. SelSA exhibits antitumor activity in mouse model [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1225038-92-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162616. | |
| Seltorexant | Seltorexant (JNJ-42847922) is an orally active, high-affinity, and selective orexin-2 receptor (OX2R) antagonist ( pK i values of 8.0 and 8.1 for human and rat OX2R). Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-42847922. CAS No. 1293281-49-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109012. | |
| Seltorexant hydrochloride | Seltorexant hydrochloride (JNJ-42847922 hydrochloride) is an orally active, high-affinity, and selective OX2R antagonist ( pK i values of 8.0 and 8.1 for human and rat OX2R). Seltorexant hydrochloride crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-42847922 hydrochloride. CAS No. 1293284-49-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109012A. | |
| Selumetinib | Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC 50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD6244; ARRY-142886. CAS No. 606143-52-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50706. | |
| Selumetinib sulfate | Selumetinib (AZD6244) is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC 50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1/2 phosphorylation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD6244 sulfate; ARRY-142886 sulfate. CAS No. 943332-08-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50706A. | |
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