MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Orphenadrine citrate | Orphenadrine citrate is an orally active and non-competitive NMDA receptor antagonist (crosses the blood-brain barrier) with a K i of 6.0 μM. Orphenadrine citrate relieves stiffness, pain and discomfort due to muscle strains, sprains or other injuries. Orphenadrine citrate is also used to relieve tremors associated with parkinson's disease. Orphenadrine citrate has good neuroprotective properties, can be used in studies of neurodegenerative diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4682-36-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0369A. |  |
| Orsellinic acid | Orsellinic acid is a compound produced by Lecanoric acid treated with alcohols. Lecanoric acid is a lichen depside isolated from a Parmotrema tinctorum specimen [1]. Uses: Scientific research. Group: Natural products. CAS No. 480-64-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N3126. | |
| Orteronel | Orteronel (TAK-700) is a highly selective inhibitor of human 17,20-lyase (CYP17) with IC 50 of 38 nM, and exhibits >1000-fold selectivity over other CYPs such as 11-hydroxylase and CYP3A4 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-700. CAS No. 566939-85-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10505. | |
| Orticumab | Orticumab (MLDL1278A) is an antibody targeting to oxidized or malondialdehyde-modified lipoprotein (LDL). Orticumab specifically inhibits oxidized low-density lipoproteins ( oxLDL ). Orticumab involves in modulation of autoimmune responses against oxLDL, improves atherosclerosis in animal model. Orticumab also can be used for research of psoriasis improvement [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MLDL1278A. CAS No. 1314241-10-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99793. | |
| Orvepitant maleate | Orvepitant maleate (GW823296 maleate) is potent, selective, orally active and well-tolerated neurokinin-1 receptor (NK-1) antagonist with a pK i of 10.2 for human neurokinin-1 receptor. Orvepitant maleate can across the blood-brain barrier. Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatment [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW823296 maleate. CAS No. 579475-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122347A. | |
| Oryzalin | Oryzalin is a dinitroaniline herbicide, binding to plant tubulin and inhibits microtubule (MT) polymerization in vitro. Oryzalin depolymerizes MTs and prevented the polymerization of new MTs at all stages of the mitotic cycle [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19044-88-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-147092. | |
| Orziloben | Orziloben is a medium chain fatty acid (MCFA) analogue [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1555822-28-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156629. | |
| Os30 | Os30, a potent fourth-generation EGFR inhibitor, is a potent EGFRC797S-TK inhibitor with IC 50 values of 18 nM and 113 nM for EGFRDel19/T790M/C797S TK and EGFRL858R/T790M/C797S TK, respectively. Os30 can suppress EGFR phosphorylation, arrest at G1 phase and induce the apoptosis of KC-0116 (BaF3-EGFRDel19/T790M/C797S) cells. Os30 shows potent antitumor efficacy on non-small cell lung cancer (NSCLC) with EGFmRC797S mutation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2998928-68-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155358. | |
| Osalmid | Osalmid is a ribonucleotide reductase small subunit M2 (RRM2) targeting compound; suppresses ribonucleotide reductase activity with an IC50 of 8.23 ?M. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Oxaphenamide; 4'-Hydroxysalicylanilide. CAS No. 526-18-1. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-B2116. | |
| Osanetant | Osanetant (SR142801) is a selective NK3 receptor antagonist. Osanetant produces anxiolytic- and antidepressant-like effects and is researched for schizophrenia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR142801. CAS No. 160492-56-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14551. | |
| Osavampator | Osavampator (TAK-653) is a AMPA receptor positive allosteric modulator. Osavampator selectively binds to AMPA-R in a glutamate-dependent manner and induces Ca 2+ influx in hGluA1i CHO cells (EC 50 = 3.3 μM). Osavampator improves learning and memory in many models. Osavampator is can be used for the research of depressive disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-653; NBI-1065845. CAS No. 1358751-06-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115864. | |
| Osbond acid | Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: all-cis-4,7,10,13,16-Docosapentaenoic acid. CAS No. 25182-74-5. Pack Sizes: 1 mg (30.26 mM * 100 μL in Ethanol). Product ID: HY-N7864. | |
| Oseltamivir | Oseltamivir (GS 4104) is an orally active influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC 50 s of 0.67, 0.9, 1.34 and 13 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS 4104. CAS No. 196618-13-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-13317. | |
| Oseltamivir acid | Oseltamivir acid (GS 4071), the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS 4071; Ro 64-0802; Oseltamivir carboxylate. CAS No. 187227-45-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13318. | |
| Oseltamivir phosphate | Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS 4104 phosphate. CAS No. 204255-11-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17016. | |
| Osemitamab | Osemitamab is an IgG1 antibody targeting to human claudin-18.2. Osemitamab consists of human-Mus musculus monoclonal TST001 γ1-chain, disulfide with human-Mus musculus monoclonal TST001 κ-chain, dimer (ACI). Osemitamab in combination with Capecitabine (HY-B0016) and Oxaliplatin (HY-17371), can be used for G/GEJ cancer study [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TST001. CAS No. 2460539-61-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9991. | |
| OSI-027 | OSI-027 (ASP7486) is a potent, selective, orally active and ATP-competitive mTOR kinase activity inhibitor with an IC 50 of 4 nM. OSI-027 targets both mTORC1 and mTORC2 with IC 50 s of 22 nM and 65 nM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASP7486. CAS No. 936890-98-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10423. | |
| OSI-930 | OSI-930 is an orally selective inhibitor of Kit , KDR and CSF-1R (c-Fms) with IC 50 s of 80 nM, 9 nM and 15 nM, respectively. OSI-930 also moderately inhibits Flt-1 , c-Raf , Lck and low activity against PDGFRα/β , Flt-3 and Abl. OSI-930 has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 728033-96-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-10204. | |
| Osilodrostat | Osilodrostat (LCI699) is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC 50 value of 35 nM. Osilodrostat is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC 50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat inhibits aldosterone and corticosterone synthesis. Osilodrostat has blood pressure lowering ability. Osilodrostat can be used for research of Cushing syndrome (CS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCI699. CAS No. 928134-65-0. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16276. | |
| Osilodrostat phosphate | Osilodrostat (LCI699) phosphate is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC 50 value of 35 nM. Osilodrostat phosphate is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC 50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat phosphate inhibits aldosterone and corticosterone synthesis. Osilodrostat phosphate has blood pressure lowering ability. Osilodrostat phosphate can be used for research of Cushing syndrome (CS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCI699 phosphate. CAS No. 1315449-72-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16276A. | |
| Osimertinib | Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC 50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD-9291; Mereletinib. CAS No. 1421373-65-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15772. | |
| Osimertinib mesylate | Osimertinib mesylate (AZD9291 mesylate) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC 50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD-9291 mesylate; Mereletinib mesylate. CAS No. 1421373-66-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15772A. | |
| Osimertinib (Standard) | Osimertinib (Standard) is the analytical standard of Osimertinib. This product is intended for research and analytical applications. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC 50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1421373-65-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15772R. | |
| Osivelotor | Osivelotor is an orally effective small molecule. Osivelotor is an allosteric regulator of deoxyhemoglobin S (HbS). Osivelotor increases the affinity of HbS to oxygen, inhibits HbS polymerization, and thus prevents erythrocyte sickling in the blood. Osivelotor can be used for research of sickle cell disease (SCD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GBT-601; GBT-021601. CAS No. 2417955-18-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148788. | |
| OSMI-1 | OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor with an IC50 value of 2.7 ?M. OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1681056-61-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-119738. | |
| OSMI-2 | OSMI-2 (Compound 1b) is a cell-permeable O-linked N-acetylglucosamine transferase (OGT) inhibitor. Cells contain a large nuclear pool of partially spliced OGT transcript, and OSMI-2 increases detained intron splicing in cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2260542-60-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135784. | |
| OSMI-4 | OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor, with an EC50 of 3 ?M in cells. Uses: Scientific research. Group: Signaling pathways. CAS No. 2260791-14-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114361. | |
| OSM-SMI-10B | OSM-SMI-10B a derivative of OSM-SMI-10. OSM-SMI-10B significantly reduces OSM-induced STAT3 phosphorylation in cancer cells upon co-incubation with OSM (Oncostatin M)[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148692. | |
| Osocimab | Osocimab (BAY 1213790), an anti- FXIa antibody (K i =2.4 nM; EC 50 =0.2 nM). FXI inhibition may reduce the risk of thrombosis. Osocimab inhibits thrombin generation, and prolongs activated partial thromboplastin time. Osocimab exhibits anticoagulant effects [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BAY 1213790. CAS No. 2056878-75-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99794. | |
| Osoresnontrine | Osoresnontrine (BI-409306) is a potent and selective PDE9A inhibitor, with an IC 50 of 52 nM, and shows weak activity against other PDEs, such as PDE1A ( IC 50 , 1.4 μM), PDE1C ( IC 50 , 1.0 μM), PDE2A, PDE3A, PDE4B, PDE5A, PDE6AB, PDE7A, and PDE10A ( IC 50 all > 10 μM); Osoresnontrine can be used in the research of memory enhancement in CNS disorders. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI-409306. CAS No. 1189767-28-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-112831. | |
| Ospemifene | Ospemifene is a non-estrogen selective estrogen receptor modulator (SERM), with K i s of 380 and 410 nM for estrogen receptor α (ERα) and ERβ , respectively. Ospemifene can be used for the research of vaginal atrophy and breast cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FC-1271a. CAS No. 128607-22-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0723. | |
| OSS_128167 | OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC50s of 89 ?M, 1578 ?M and 751 ?M for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-cancer, anti-inflammation and anti-viral effects[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 887686-02-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107454. | |
| Ostarine | Ostarine (MK-2866) is a selective androgen receptor modulator (SARMs) that regulates cardiomyocyte function, improves bone healing, regulates uterine function, and influences muscle tissue metabolism [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-2866; GTX-024; Enobosarm. CAS No. 841205-47-8. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-13273. | |
| Osteogenic Growth Peptide, OGP | Osteogenic Growth Peptide, OGP is a short, naturally occurring 14-mer growth factor peptide found in serum at μM concentrations. Uses: Scientific research. Group: Peptides. CAS No. 132996-61-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1563. | |
| Osthole | Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H 1 receptor activity. Osthole also suppresses the secretion of HBV in cells. Uses: Scientific research. Group: Natural products. Alternative Names: Osthol; NSC 31868. CAS No. 484-12-8. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0054. | |
| Ostruthin | Ostruthin (Ostruthine) is an antimycobacterial coumarin, that can be isolated from the roots of Peucedanum ostruthium. Ostruthin causes a marked inhibition of the growth of gram-positive micro-organisms [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ostruthine. CAS No. 148-83-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W506116. | |
| OSU-03012 | OSU-03012 (AR-12; PDK1 inhibitor AR-12) is a blood-brain permeable PDK-1 inhibitor with an IC50 of 5 ?M[1][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AR-12; PDK1 inhibitor AR-12. CAS No. 742112-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10547. | |
| Osunprotafib | Osunprotafib (ABBV-CLS-484) is an orally active and selective active site PTPN1 (IC50: 2.5?nM) and PTPN2(IC50: 1.8?nM) inhibitor. Osunprotafib has 6-8-fold weaker activity on PTPN9 and no detectable activity on SHP-1 or SHP-2. Osunprotafib increases the sensitivity of human cancer cell lines to IFN?. Osunprotafib generates robust anti-tumor immunity by enhancing JAK-STAT signalling and reducing T?cell dysfunction[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABBV-CLS-484. CAS No. 2489404-97-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-145923. | |
| OSU-T315 | OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 ?M, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3? and myosin light chain)[1]. OSU-T315 abrogates AKT activation by impeding AKT localization in lipid rafts and triggers caspase-dependent apoptosis in an ILK-independent manner[2]. OSU-T315 causes cell death through apoptosis and autophagy[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2070015-22-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18676. | |
| OT-82 | OT-82 is a potent, selective and orally active inhibitor of NAMPT. OT-82 is selectively toxic to cells of hematopoietic origin and induces cell death in a NAD + dependent manner. OT-82 is a promising antineoplastic agent for the study of hematological malignancies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1800487-55-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136241. | |
| Otamixaban | Otamixaban(FXV673) is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FXV673. CAS No. 193153-04-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70035. | |
| Otelixizumab | Otelixizumab (ChAglyCD3) is an anti-human CD3 monoclonal antibody and can be used for the research of type 1 diabetes [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ChAglyCD3; TRX 4. CAS No. 881191-44-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99211. | |
| O-(tert-Butyl)-L-serine | O-(tert-Butyl)-L-serine is a serine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 18822-58-7. Pack Sizes: 10 g; 25 g; 100 g; 500 g. Product ID: HY-W010156. | |
| Oteseconazole | Oteseconazole (VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 ( CYP51 ) activity ( K d ≤39 nM ), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VT-1161. CAS No. 1340593-59-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17643. | |
| Otilimab | Otilimab (GSK 3196165) is an anti- granulocyte-macrophage colony-stimulating factor (GM-CSF) human monoclonal antibody. Otilimab neutralises the biological function of GM-CSF by blocking the interaction of GM-CSF with its cell surface receptor [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GSK 3196165; MOR103. CAS No. 1638332-55-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99795. | |
| Otilonium bromide | Otilonium bromide (OB) is an orally active mAChR inhibitor and smooth muscle relaxant which can interfere with the mobilization of calcium in intestinal smooth muscle, OB can be used for research of irritable bowel syndrome [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Octylonium bromide; SP63. CAS No. 26095-59-0. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0499A. | |
| Otlertuzumab | Otlertuzumab (TRU-016) is a humanized anti- CD37 monoclonal antibody that can be used for cancer research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TRU-016. CAS No. 1372645-37-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99212. | |
| o-Toluic acid | O-toluic acid (2-Methylbenzoic acid) is an organic compound that is benzoic acid with a methyl group substituted at the 2-position. O-toluic acid can act as an exogenous metabolite and holds some chemical research value [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Methylbenzoic acid. CAS No. 118-90-1. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-41494. | |
| OTS186935 | OTS186935 is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. OTS186935 shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 regulates the production of ?-H2AX in cancer cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2093400-18-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122181. | |
| OTS186935 hydrochloride | OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. OTS186935 hydrochloride shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 hydrochloride regulates the production of ?-H2AX in cancer cells[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122181B. | |
| OTS193320 | OTS193320, a imidazo[1,2-a]pyridine compound, is a SUV39H2 methyltransferase activity inhibitor. OTS193320 decreases global histone H3 lysine 9 tri-methylation levels in breast cancer cells and triggers apoptotic cell death. Combination of OTS193320 with Doxorubicin (DOX; HY-15142A) results in reduction of ?-H2AX levels as well as cancer cell viability compared to a single agent OTS193320 or DOX[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2093401-33-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-122182. | |
| OTS514 | OTS514 is a highly potent TOPK inhibitor with an IC 50 of 2.6 nM. OTS514 strongly suppresses the growth of TOPK-positive cancer cells [1]. OTS514 induces cell cycle arrest and apoptosis [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1338540-63-8. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18621. | |
| OTS964 hydrochloride | OTS964 hydrochloride is an orally active, high affinity and selective TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor with an IC50 of 28 nM[1]. OTS964 hydrochloride is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a Kd of 40 nM[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1338545-07-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12467. | |
| OTSSP167 | OTSSP167 (OTS167) is a highly potent and ATP-competitive MELK inhibitor with IC50 value of 0.41 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OTS167. CAS No. 1431697-89-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-15512. | |
| OTSSP167 hydrochloride | OTSSP167 (OTS167) hydrochloride is a highly potent and ATP-competitive MELK inhibitor with IC50 value of 0.41 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OTS167 hydrochloride. CAS No. 1431698-10-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15512A. | |
| OTUB1/USP8-IN-1 | OTUB1/USP8-IN-1 is a potent dual OTUB1/USP8 inhibitor with IC 50 values of 0.17 and 0.28 nM for OTUB1 and USP8, respectively. OTUB1/USP8-IN-1 can be used in research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2858800-98-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151563. | |
| OTX008 | OTX008 is a selective inhibitor of galectin-1. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Calixarene 0118; PTX008. CAS No. 286936-40-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19756. | |
| Ovalbumin-Biotin | Ovalbumin-Biotin is a biotinylated biochemical reagent. Ovalbumin-Biotin is used to label or detect specific antigens, molecules or cellular structures[1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: OVA-Biotin. Pack Sizes: 100 ?L; 1 mL. Product ID: HY-NP052. | |
| Ovalbumin-PE | Ovalbumin-PE is Cy5-labeled Ovalbumin (OVA)[1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: OVA-PE. Pack Sizes: 100 ?L; 1 mL. Product ID: HY-NP030. | |
| Ovalbumins | Ovalbumins (OVA), the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone regulation of gene expression in tissues [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9006-59-1. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-W250978. | |
| o-Vanillin | o-Vanillin (2-Vanillin) is a nature product, could be extracted from Vanilla planifolia, Pinus koraiensis fruit. o-Vanillin is a potent antifungal agent. o-Vanillin inhibits the growth of mycelia by disrupting the integrity of cell walls and cell membranes. o-Vanillin inhibits Doxorubicin (HY-15142A)- and 4-hydroperoxycyclophosphamide-induced NF-κB activation [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3-Methoxysalicylaldehyde. CAS No. 148-53-8. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-Y1832. | |
| OVA peptide | OVA peptide mainly exists in egg white, it is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC). OVA peptide has been widely studied in allergy research [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 141312-45-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3715. | |
| OVA Peptide(257-264) | OVA Peptide(257-264) is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb. Uses: Scientific research. Group: Peptides. CAS No. 138831-86-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1489. | |
| OVA Peptide (323-339) | OVA Peptide (323-339) represents a T and B cell epitope of Ovalbumin (Ova), which is important in the generation and development of immediate hypersensitivity responses in BALB/c mice. Uses: Scientific research. Group: Peptides. CAS No. 92915-79-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0286. | |
| OXA-06 hydrochloride | OXA-06 hydrochloride is an ATP-competitive ROCK inhibitor that blocks anchorage-dependent growth and invasion of non-small cell lung cancer cell lines. OXA-06 hydrochloride inhibits cofilin phosphorylation but does not stimulate apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1825455-91-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110335. | |
| OXA(17-33) | OXA(17-33) is a potent and selective orexin-1 receptor (OX1) agonist. OXA(17-33) shows a ?23-fold selectivity for the OX1 ( EC 50 =8.29 nM) over OX2 (187 nM) [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Orexin A (17-33) (human, mouse, rat, bovine). CAS No. 343268-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1341. | |
| Oxaceprol | Oxaceprol (N-Acetyl-L-hydroxyproline), an orally active derivative of L-proline, possesses distinct anti-inflammatory activity. Oxaceprol is usually used for the research of osteoarthritis and rheumatoid arthritis [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: N-Acetyl-L-hydroxyproline. CAS No. 33996-33-7. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g; 25 g. Product ID: HY-17490. | |
| Oxacillin sodium monohydrate | Oxacillin sodium monohydrate is an antibiotic similar to Flucloxacillin used in resistant staphylococci infections study [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7240-38-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0465. | |
| Oxacillin sodium salt | Oxacillin sodium salt is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1173-88-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0925. | |
| Oxadiazon | Oxadiazon is a pre-emergent herbicide used for the control of various annual monocot and dicot weeds. Uses: Scientific research. Group: Signaling pathways. CAS No. 19666-30-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1880. | |
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