MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| (S)-(-)-Propranolol hydrochloride | (S)-(-)-Propranolol hydrochloride is a β-adrenergic receptor antagonist with log K d values of -8.16, -9.08, and -6.93 for β 1 , β 2 , and β 3 , respectively. (S)-(-)-Propranolol hydrochloride the active enantiomer of propranolol and can be s used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4199-10-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0573A. |  |
| (S)-p-SCN-Bn-DOTA | (S)-p-SCN-Bn-DOTAis a bifunctional chelator ( Bifunctional Chelator ; BFC ) and a macrocyclic DOTA derivative used for tumor pre-targeting. (S)-p-SCN-Bn-DOTA can be used for conjugation of peptides and radionuclides. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1020407-41-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156038. | |
| SQ109 | SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC 50 for cell killing of 50±8 nM. SQ109, targets MmpL3 , is an antitubercular agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 722041. CAS No. 502487-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14989. | |
| SQDG | SQDG is a glycolipid that possesses sugar moieties in their head groups. SQDG is a membrane lipid that can be used to investigate the effects of structural lipid in LNP formulations [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 123036-44-2. Pack Sizes: 1 mg. Product ID: HY-143692. | |
| Squalamine | Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson , s disease mouse models [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: MSI-1256. CAS No. 148717-90-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16468. | |
| Squalamine lactate | Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration. Uses: Scientific research. Group: Natural products. Alternative Names: MSI-1256F. CAS No. 320725-47-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16467. | |
| Squalane | Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 111-01-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N7113. | |
| Squalene | Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Super Squalene; trans-Squalene; AddaVax. CAS No. 111-02-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1214. | |
| Squalene (Standard) | Squalene (Standard) is the analytical standard of Squalene. This product is intended for research and analytical applications. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 111-02-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1214R. | |
| (S)-Quinuclidin-3-amine dihydrochloride | (S)-Quinuclidin-3-amine dihydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (S)-3-Aminoquinuclidine dihydrochloride. CAS No. 119904-90-4. Pack Sizes: 1 g; 5 g. Product ID: HY-I0034. | |
| SR1001 | SR1001 is a selective ROR α and ROR γt inverse agonist with K i s 172 and 111 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1335106-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13421. | |
| SR 11023 | SR 11023 is an orally active antagonist of PPAR γ, with the IC 50 value of 109 nM that plays an important role in diabetic research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1820602-13-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160162. | |
| SR12813 | SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase , with an IC 50 value of 0.85 μM [1] [2]. SR12813 is also an efficient agonist of human pregnane X receptor ( hPXR ). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR) [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW 485801. CAS No. 126411-39-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100793. | |
| SR 142948 | SR 142948 is an orally active and selective non-peptide neurotensin receptor ( NT ) antagonist with IC 50 s of 1.19 nM, 0.32 nM, 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. SR 142948 antagonizes NT-induced inositol monophosphate formation in HT-29 cells with an IC50 of 3.9 nM. SR 142948 blocks hypothermia, analgesia and steering behavior induced by NT in vivo. SR 142948 shows blood-brain permeability and can be used in study of psychiatric disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 184162-64-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107664. | |
| SR 142948A | SR 142948A is a non-peptide neuropeptide neuropeptin ( NT ) receptor antagonist. SR 142948A is able to bind to neuropeptin receptors, especially with high affinity for NT1 and NT2 receptors. SR 142948A is mainly used to study the role of neuropeptide in the neurotransmitter system, especially the dopamine system [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 184162-21-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-124767. | |
| SR 16832 | SR 16832 is a dual site covalent PPARγ inhibitor that acts at orthosteric and allosteric sites [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2088135-12-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112247. | |
| SR17018 | SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC 50 of 97 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 2134602-45-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111454. | |
| SR-31747 | SR-31747 is a sigma ligand with immunosuppressive and anti-inflammatory properties. SR-31747 blocks cell proliferation by inhibiting sterol isomerase [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 132173-07-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13751. | |
| SR33805 | SR33805 is a potent Ca 2+ channel antagonist, with EC 50 s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively. SR33805 blocks L-type but not T-type Ca 2+ channels. SR33805 can be used for the research of acute or chronic failing hearts [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 121345-64-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136909. | |
| SR 49059 | SR 49059 (SR-49059) is a potent, orally active, selective vasopressin V1a antagonist with a K i vaule of 1.4 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 150375-75-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18345. | |
| SR 57227A | SR 57227A is a potent, orally active and selective 5-HT3 receptor agonist, with ability to cross the blood brain barrier. SR 57227A has affinities (IC 50 ) varying between 2.8 and 250 nM for 5-HT3 receptor binding sites in rat cortical membranes and on whole NG 108-15 cells or their membranes. Anti-depressant effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 77145-61-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-102064. | |
| SR8278 | SR8278 is a REV-ERBα antagonist and inhibits the REV-ERBα transcriptional repression activity with an EC 50 of 0.47 μM. SR8278 is used to regulate the metabolism in organisms and study biological rhythm. SR8278 also can be used for the research of Duchenne muscular dystrophy and Alzheimer's disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1254944-66-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14415. | |
| SR9009 | SR9009 is a REV-ERBα/β agonist with IC 50 s of 670 nM and 800 nM for REV-ERBα and REV-ERBβ, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1379686-30-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16989. | |
| SR9011 | SR9011 is a REV-ERBα / β agonist with IC 50 s of 790 nM and 560 nM for REV-ERBα and REV-ERBβ, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1379686-29-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16988. | |
| SR9011 hydrochloride | SR9011 hydrochloride is a REV-ERBα / β agonist with IC 50 s of 790 nM and 560 nM for REV-ERBα and REV-ERBβ, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 2070014-94-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16988A. | |
| (S)-Rasagiline | (S)-Rasagiline (TVP1022) is the relatively inactive S-enantiomer form of Rasagiline. Rasagiline is a highly potent selective irreversible MAO inhibitor with IC 50 s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively [1]. (S)-Rasagiline is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TVP1022; S-PAI. CAS No. 185517-74-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14200. | |
| SRC-3-IN-2 | SRC-3-IN-2 (SI-12 6c)is an orally active steroid receptor coactivator 3 ( SRC-3 ) inhibitor. SRC-3-IN-2 has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3074959-44-4. Pack Sizes: 1 mg. Product ID: HY-163469. | |
| (S)-Remoxipride hydrochloride | (S)-Remoxipride ((-)-Remoxipride) hydrochloride is a selective dopamine D 2 -receptor antagonist with an IC 50 value of 1.57 μM. (S)-Remoxipride hydrochloride can be used for the research of psychotic disorder [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Remoxipride hydrochloride. CAS No. 73220-03-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101313A. | |
| (S)-RLY-2608 | (S)-RLY-2608 is an S-enantiomer of of RLY-2608 (HY-153306). RLY-2608 is an orally active first-in-class allosteric mutant-selective inhibitor of PI3Ka with anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2733573-93-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153306A. | |
| (S)-(+)-Rolipram | (S)-(+)-Rolipram ((+)-Rolipram) is a cyclic AMP(cAMP)-specific phosphodiesterase 4 (PDE4) inhibitor, with an IC 50 of 1100 nM. (S)-(+)-Rolipram can suppresse tumor necrosis factor-alpha (TNFα) production by human mononuclear cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Rolipram; (S)-Rolipram. CAS No. 85416-73-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0392. | |
| (S,R,S)-AHPC | (S,R,S)-AHPC (VH032-NH2) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC 50 of 1.11 μM in Ba/F3 cells [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VH032-NH2; VHL ligand 1. CAS No. 1448297-52-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-125845. | |
| (S,R,S)-AHPC-C3-NH2 hydrochloride | (S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VH032-C3-NH2 hydrochloride. CAS No. 2940858-65-9. Pack Sizes: 50 mg; 100 mg. Product ID: HY-130711B. | |
| (S,R,S)-AHPC-C5-COOH | (S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized E3 ligase ligand-linker conjugate , contains the VH032 VHL-based ligand and a linker to form PROTAC s. VH-032 is a selective and potent inhibitor of VHL/HIF-1α interaction with a K d of 185 nM, has the potential for the study of anemia and ischemic diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VH032-C5-COOH. CAS No. 2267282-19-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136055. | |
| SRT 1720 | SRT 1720 is a selective activator of human SIRT1 with an EC 1.5 of 0.16 μM, and shows less potent activities for SIRT2 and SIRT3 with EC 1.5 s of 37 μM and > 300 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 925434-55-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10532. | |
| SRT 1720 dihydrochloride | SRT 1720 dihydrochloride is a selective and orally active activator of SIRT1 with an EC 50 of 0.10 μM, and shows less potent activities on SIRT2 and SIRT3 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2468639-77-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15145A. | |
| SS-208 | SS-208 is a selective HDAC6 inhibitor, with an IC 50 of 12 nM. SS-208 possesses anti-tumor activity in melanoma [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AVS100. CAS No. 2245942-72-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126330. | |
| (S)-Salsolinol | (S)-Salsolinol ((-)-Salsolinol) is a dopamine-derived endogenous metabolite [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Salsolinol. CAS No. 27740-96-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113316B. | |
| (S,S)-CPI-1612 | (S,S)-CPI-1612 is the isomer of CPI-1612 (HY-136285), and can be used as an experimental control. CPI-1612 is a highly potent, orally active EP300/CBP histone acetyltransferase (HAT) inhibitor with an IC 50 of 8.1 nM for EP300 HAT. CPI-1612 has an anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2374971-82-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-145386. | |
| SSI-4 | SSI-4 is an inhibitor of Stearoyl CoA desaturase 1 (SCD1) , which can be modified with 11 C, used as a ligand to in vivo small animal PET/CT imaging of SCD1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1875084-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155033. | |
| (S)-SNAP5114 | (S)-SNAP5114 is a selective GABA transport inhibitor, with IC 50 values of 5 μM and 21 μM for hGAT-3 and rGAT-2, respectively. (S)-SNAP5114 is an anticonvulsant agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 157604-55-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103504. | |
| ß-pBrPh-Glc | β-pBrPh-Glc is a small-molecule ice recrystallization inhibitor. β-pBrPh-Glc can control the rate and extent of intracellular ice recrystallization in the nuclei over a broad range of subzero temperatures. β-pBrPh-Glc is an important tool to improve the recovery and function of cryopreserved cells and tissues [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 30572-42-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124020. | |
| SSR128129E | SSR128129E is an orally available and allosteric FGFR inhibitor with an IC 50 of 1.9 μM for FGFR1. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SSR. CAS No. 848318-25-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15599. | |
| SSR180711 hydrochloride | SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. SSR180711 hydrochloride can act on rat α7 n-AChR ( K i =22 nM; IC 50 =30 nM) and human α7 n-AChR ( K i =14 nM; IC 50 =18 nM). SSR180711 hydrochloride increases glutamatergic neurotransmission, ACh release and long-term potentiation (LTP) in the hippocampus [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 446031-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19411. | |
| SSR504734 | SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 ( IC 50 =18, 15, and 38?nM, respectively). SSR504734 shows anti-schizophrenia, anti-anxiety and anti-depression activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 615571-23-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10715. | |
| SSTR5 antagonist 2 hydrochloride | SSTR5 antagonist 2 hydrochloride is a highly potent, oral active and selective somatostatin (receptor) subtype 5 (SSTR5) antagonist and has potential for the research of type 2 diabetes mellitus (T2DM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2988224-31-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114191B. | |
| (S,S)-TsDPEN | (S,S)-N-p-Toluenesulfonyl-1,2-diphenylethylenediamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 167316-27-0. Pack Sizes: 5 g; 10 g. Product ID: HY-Y1108. | |
| (S)-STX-478 | (S)-STX-478 is the S-enantiomer of STX-478. STX-478 is a selective inhibitor of PI3Kα mutants, preventing metabolic dysfunction and demonstrating antitumor activity in xenograft mouse models with PI3Kα mutant tumors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2883540-91-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156681A. | |
| ST1936 | ST1936 is a selective, nanomolar affinity 5-HT 6 receptor agonist with K i values of 13 nM, 168 nM and 245 nM for human 5-HT 6 , 5-HT 7 and 5-HT 2B receptors, respectively. ST1936 also shows moderate affinity (K i of 300 nM) for human and rat α2 adrenergic receptor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1210-81-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103110. | |
| ST271 | ST271 is a potent inhibitor of protein tyrosine kinase ( PTK ), inhibits phospholipase D activation stimulated by fMet-Leu-Phe and PAF, with IC 50 s of 6.7 and 9 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 106392-48-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103097. | |
| ST-401 | ST-401, a microtubule-targeting agent (MTA), is a brain-penetrant microtubule (MT) assembly inhibitor. ST-401 disrupts microtubule (MT) function through gentle and reverisible reduction in MT assembly that triggers mitotic delay and cell death in interphase. ST-401 shows a potent antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2419942-78-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163737. | |
| ST91 | ST91 is a α 2 -adrenoceptor (α 2 AR) agonist. ST91 activates both α 2A AR and non-α 2A AR subtypes to produce spinal antinociception [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4749-61-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103203. | |
| Stachydrine | Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF-κB signal pathway. Uses: Scientific research. Group: Natural products. CAS No. 471-87-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0298. | |
| Stachydrine hydrochloride | Stachydrine hydrochloride is the major active constituent of Leonurus artemisia , which is a potential therapy for cardiovascular diseases [2]. Stachydrine can inhibit the NF-κB signal pathway. Anti-hypertrophic activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 4136-37-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0738. | |
| Stachyose | Stachyose, a kind of oligosaccharides, act as a hypoglycemic agent [1]. Uses: Scientific research. Group: Natural products. CAS No. 470-55-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7910. | |
| Stachyose hydrate | Stachyose hydrate is an orally active prebiotic that enhances the growth and activity of beneficial bacteria. Stachyose hydrate has hypoglycemic effects and can improve inflammation by regulating gut microbiota. In addition, Stachyose hydrate can induce plant cell apoptosis ( Apoptosis ). Stachyose hydrate can be used in research on inflammation, gastrointestinal diseases, and agriculture [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 54261-98-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0299. | |
| Stafia-1 | Stafia-1 is a potent STAT5a inhibitor ( K i =10.9 μM, IC 50 =22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2582757-90-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136546. | |
| Stafib-2 | Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b , with an IC 50 of 82 nM and 1.7 μM for STAT5b and STAT5a , respectively. Stafib-2 exhibits poor cell permeability [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2097938-74-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112648. | |
| Stains-All | Stains-All, a cationic carbocyanine dye, is a convenient probe to study the structural features of the individual calcium-binding sites of calmodulin (CaM) and related calcium-binding proteins (CaBP) [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 7423-31-6. Pack Sizes: 10 mM * 1 mL; 200 mg. Product ID: HY-D0987. | |
| Stapokibart | Stapokibart (CM310) is a humanised monoclonal antibody targeting IL-4Rα and efficiently blocks the interaction of cytokines IL-4 and IL-13 with their co-receptor subunit IL-4R&alpha. Stapokibart has the capacity to interact with IL-4Rα in humans, cynomolgus monkeys, and rats [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CM310. CAS No. 2734715-10-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990093. | |
| Starch (from potato) | Starch from potato is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Edible corn starch (from potato). CAS No. 9005-25-8. Pack Sizes: 100 g. Product ID: HY-B2225A. | |
| Starch soluble | Starch soluble is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9005-84-9. Pack Sizes: 5 g. Product ID: HY-W094695. | |
| STAT3-IN-14 | STAT3-IN-14 (Compound 1) is a STAT3 inhibitor and has STAT3 phosphorylation inhibitory activity. STAT3-IN-14 (Compound 1) can directly bind to the hinge region of STAT3 [1]. Uses: Scientific research. Group: Natural products. CAS No. 123297-90-5. Pack Sizes: 1 mg. Product ID: HY-N10472. | |
| STAT3-IN-17 | STAT3-IN-17 is a moderate STAT3 inhibitor ( IC 50 =0.7 μM; HEK-Blue IL-6), with antiproliferative activity in HeLa cells. STAT3-IN-17 has good pharmacokinetic characteristics. STAT3-IN-17 also inhibits pyruvate-ferredoxin oxidoreductase ( PFOR ), and inhibits Helicobacter pylori [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1245814-52-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148706. | |
| STAT3-IN-25 | STAT3-IN-25 (compound 2p) is a potent STAT3 inhibitor with a p-trifluoroethoxy benzyl substituent. STAT3-IN-25 shows STAT3 luciferase inhibition activity using HEK293T cells with an IC 50 of 22.3 nM and ATP production inhibition activity using BxPC-3 cells with an IC 50 of 32.5 nM. STAT3-IN-25 shows potent antiproliferation activities on BxPC-3 and Capan-2 cells. STAT3-IN-25 has the potential for pancreatic cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2591440-75-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160496. | |
| Statine | Statine is an unusual amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (3S,4S)-Statine; (S,S)-Statine. CAS No. 49642-07-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101877. | |
| Stattic | Stattic is a potent STAT3 inhibitor and inhibits STAT3 phosphorylation (at Y705 and S727) [1]. Stattic inhibits the binding of a high affinity phosphopeptide for the SH2 domain of STAT3 [2]. Stattic ameliorates the renal dysfunction in Alport syndrome (AS) mice [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19983-44-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13818. | |
| Stavudine | Stavudine (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Stavudine has activity against HIV-1 and HIV-2. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: d4T. CAS No. 3056-17-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0116. | |
| Stavudine (Standard) | Stavudine (Standard) is the analytical standard of Stavudine. This product is intended for research and analytical applications. Stavudine (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Stavudine has activity against HIV-1 and HIV-2. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3056-17-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0116R. | |
| Stearamide | Stearamide is a primary fatty acid amide. Stearamide displays cytotoxic and ichthytoxic activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 124-26-5. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-W130610. | |
| Stearic acid | Stearic acid is a long-chain dietary saturated fatty acid that can significantly reduce visceral fat by inducing apoptosis of preadipocytes. Stearic acid can be used in the study of cardiovascular and metabolic diseases [1]. Uses: Scientific research. Group: Natural products. CAS No. 57-11-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B2219. | |
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