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Ozanimod
Ozanimod (RPC-1063), a sphingosine 1-phosphate (S1P) receptor modulator that binds with high affinity selectively to S1P receptor subtypes 1 (S1P1) and 5 (S1P5). Ozanimod has modulate effect for hS1P 1 and hS1P 5 receptor with EC 50 s of 1.03 nM and 8.6 nM, respectively. Ozanimod can be used for the research of relapsing multiple sclerosis (MS) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RPC-1063. CAS No. 1306760-87-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12288.
Ozanimod hydrochloride
Ozanimod (RPC-1063) hydrochloride, a sphingosine 1-phosphate (S1P) receptor modulator that binds with high affinity selectively to S1P receptor subtypes 1 (S1P1) and 5 (S1P5). Ozanimod hydrochloride has modulate effect for hS1P 1 and hS1P 5 receptor with EC 50 s of 1.03 nM and 8.6 nM, respectively. Ozanimod hydrochloride can be used for the research of relapsing multiple sclerosis (MS) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RPC-1063 hydrochloride. CAS No. 1618636-37-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12288A.
Ozekibart
Ozekibart is an anti- TNFRSF10B monoclonal antibody [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: INBRX-109. CAS No. 2539847-03-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990715.
Ozenoxacin
Ozenoxacin is a nonfluorinated quinolone antibacterial, which shows potent activities against the main microorganisms isolated from skin and soft tissue infections. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T-3912. CAS No. 245765-41-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14957.
Ozoralizumab
Ozoralizumab (ATN-103) is an anti- TNFα humanized antibody. Ozoralizumab is a humanized trivalent nanobody compound that consists of two anti-human TNFα nanobodies and an anti-human serum albumin (HSA) nanobody. Ozoralizumab can be used in research of arthritis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ATN-103. CAS No. 1167985-17-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99796.
Ozuriftamab
Ozuriftamab is a naked human IgG1 kappa antibody of receptor tyrosine kinase-like orphan receptor 2 ROR2 , can be used to synthesis ADC [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BA302. CAS No. 2460399-44-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145626.
P005091
P005091 is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with an EC50 of 4.2 ?M. Uses: Scientific research. Group: Signaling pathways. Alternative Names: P5091. CAS No. 882257-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15667.
P11
P11 is a selective inhibitor of platelet-activating factor acetylhydrolases ( PAFAHs ) 1b2 and 1b3 that impairs cancer cell survival. P11 exhibits IC 50 values of ~40 and 900 nM for PAFAH1b2 and 1b3, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 942285-55-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-111053.
P110 heptapeptide
P110 heptapeptide is a peptide inhibitor of the Drp1-Fis1 interaction. P110 heptapeptide has anti-inflammatory, immunomodulatory, mitochondrial protective, and neuroprotective activities. Without blocking the physiological functions of Drp1, P110 heptapeptide reduces pathological functions in many models of neurodegeneration, ischemia, and sepsis. P110 heptapeptide can be used for research on neurological and inflammatory diseases[1][2][3]. Uses: Scientific research. Group: Peptides. CAS No. 1411976-18-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10368.
P-113
P-113 is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5. P-113 is active against clinically important microorganisms such as Pseudomonas spp., Staphylococcus spp., and C. albicans [1]. Uses: Scientific research. Group: Peptides. CAS No. 190673-58-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2148.
P17 Peptide
P17 Peptide is a human TGF-β1 inhibitory peptide. P17 Peptide can block woodchuck TGF-β1 activity [1]. Uses: Scientific research. Group: Peptides. CAS No. 846546-36-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P10634.
P-2281
P-2281 is a mTOR inhibitor with anticancer and anti-inflammatory efficacies. P-2281 suppresses dextran sulfate sodium (DSS)-induced colitis by inhibiting T cell function and is efficacious in a murine model of human colitis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1112994-35-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-118704.
P2Y1/P2Y12 antagonist-1
P2Y1/P2Y12 antagonist-1 (compound 24w) is an orally available dual inhibitor of P2Y1 and P2Y12 with antiplatelet activity. P2Y1/P2Y12 antagonist-1 inhibits ADP-induced platelet aggregation in rabbit plasma with an IC 50 of 4.23 μM. P2Y1/P2Y12 antagonist-1 exhibits potent inhibitory effects in rat thrombosis model. Uses: Scientific research. Group: Signaling pathways. CAS No. 2738381-94-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149454.
p32 Inhibitor M36
p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M36. CAS No. 802555-85-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124718.
p38α inhibitor 3
p38α inhibitor 3 (Comp G7) is a p38α inhibitor that blocks the effectiveness of myoblast differentiation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 260428-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153002.
p38α inhibitor 5
p38α inhibitor 5 (compound 1) is a PROTAC-type target protein ligand targeting p38 and can be used to synthesize NR-11c (HY-159798) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2550397-96-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159799.
p38 MAPK-IN-1
p38 MAPK-IN-1 (Compound 4) is a novel potent and selective inhibitor of p38 MAPK with IC50 of 68 nM. p38 MAPK-IN-1 shows sustained levels, low clearance and good bioavailability. Uses: Scientific research. Group: Signaling pathways. CAS No. 1006378-90-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12839.
p38 MAPK-IN-4
p38 MAPK-IN-4 (compound 6) is a p38 MAPK inhibitor with an 50 of 35 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 219138-24-6. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-112466.
p38 MAP Kinase Inhibitor IV
p38 MAP Kinase Inhibitor IV is a highly specific ATP-competitive p38α MAPK inhibitor with IC 50 s of 0.13 and 0.55 μM for p38α and p38β MAPK, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1638-41-1. Pack Sizes: 5 mg. Product ID: HY-112401.
p53 and MDM2 proteins-interaction-inhibitor dihydrochloride
p53 and MDM2 proteins-interaction-inhibitor dihydrochloride is an inhibitor of the interaction between p53 and MDM2 proteins. Uses: Scientific research. Group: Signaling pathways. CAS No. 2070009-27-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 100 mg. Product ID: HY-70027A.
p53-MDM2-IN-1
p53-MDM2-IN-1 (Example 30) is an inhibitor of p53-MDM2/X protein interaction with an K i value of 23.35 μM. p53-MDM2-IN-1 can be used for anti-tumor research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 381717-91-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W340839.
p53-MDM2-IN-4
p53-MDM2-IN-4 (Example 4) is an inhibitor of p53-MDM2/X protein interaction, with a K i value of 3.079 μM. p53-MDM2-IN-4 can be used in anti-tumor research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 350678-63-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W340313.
P62-mediated mitophagy inducer
P62-mediated mitophagy inducer (PMI) is a P62-mediated mitophagy activator. P62-mediated mitophagy inducer activates mitochondrial autophagy without recruitment of Parkin or collapse of the mitochondrial membrane potential and remains active in cells lacking a fully functional PINK1/Parkin pathway. P62-mediated mitophagy inducer serves as a pharmacological tool to study the molecular mechanisms of mitosis, avoiding toxicity and some of the non-specific effects associated with the sudden dissipation of mitochondria lacking membrane potential[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1809031-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115576.
P7C3-A20
P7C3-A20 is a derivative of P7C3 with potent proneurogenic and neuroprotective activity. P7C3-A20 exerts an antidepressant-like effect. P7C3-A20 can cross the blood-brain barrier and therefore has the potential for brain injury treatment[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1235481-90-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15978.
PA452
PA452, retinoic X receptor ( RXR ) specific antagonist, inhibits the effect of Retinoic acid (RA) on Th1/Th2 development [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 457657-34-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108522.
PA-8
PA-8 is a potent, selective and orally active PACAP type I (PAC1) receptor antagonist. PA-8 inhibits the phosphorylation of CREB induced by PACAP in PAC1 -, but not VPAC1- or VPAC2-receptor. PA-8 also inhibits PACAP-induced cAMP elevation with an IC 50 of 2 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 878437-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133529.
PA-9
PA-9 is a pituitary adenylate cyclase-activating polypeptide (PACAP) type I ( PAC1 ) receptor antagonist. PA-9 dose dependently inhibits PACAP-induced cAMP elevation with an IC 50 of 5.6 nM. PA-9 can be used for the research of neuropathic and/or inflammatory pain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1436004-46-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129421.
Pabinafusp alfa
Pabinafusp alfa (JR-141) is a transferrin receptor -targeting antibody consisting of Iduronate 2-sulfatase (HY-P76399) and an anti-human transferrin receptor antibody. Pabinafusp alfa is blood-brain permeable and prevents heparan sulfate (HS) deposition in the central nervous system of mucopolysaccharidosis II (MPS II) mice. Pabinafusp alfa improves learning and prevents central nervous system neuronal damage in mice [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: JR-141. CAS No. 2140211-48-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99797.
PAC-1
PAC-1 is a procaspase-3 activator that induces apoptosis in cancer cells with an EC 50 of 2.08 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Procaspase activating compound 1. CAS No. 315183-21-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13523.
PACAP (1-27), human, ovine, rat
PACAP (1-27), human, ovine, rat (PACAP 1-27) is the N-terminal fragment of PACAP-38, and is a potent PACAP receptor antagonist with IC 50 s of 3 nM, 2 nM and 5 nM for rat PAC1 , rat VPAC1 and human VPAC2 , respectively [1]. Uses: Scientific research. Group: Peptides. Alternative Names: PACAP 1-27. CAS No. 127317-03-7. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P0176.
PACAP (1-38) free acid
PACAP (1-38) free acid is an endogenous neuropeptide. PACAP (1-38) free acid potently stimulates antral motility and somatostatin secretion, inhibits the secretion of gastrin and stimulates the release of vasoactive intestinal polypeptide, gastrin releasing peptide and substance P. PACAP (1-38) free acid also enhances N-methyl-D-aspartate receptor function and expression of brain-derived neurotrophic factor through RACK1 [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 129405-61-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0221C.
PACAP (1-38), human, ovine, rat
PACAP (1-38), human, ovine, rat is a neuropeptide with 38 amino acid residues. PACAP (1-38) binds to PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2 with IC50s of 4 nM, 2 nM, and 1 nM, respectively. Uses: Scientific research. Group: Peptides. Alternative Names: Pituitary Adenylate Cyclase Activating Polypeptide 38. CAS No. 137061-48-4. Pack Sizes: 500 ?g; 1 mg; 5 mg. Product ID: HY-P0221.
PACAP-38 (31-38), human, mouse, rat
PACAP-38 (31-38), human, mouse, rat is a PAC 1 receptor activator and increases the α-secretase activity. PACAP-38 (31-38), human, mouse, rat elevates cytosolic Ca 2+ , increases proliferation and increases phosphorylation of extracellular regulates kinase (ERK) and the epidermal growth factor receptor (EGFR). PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP-38 (31-38), human, mouse, rat can be used for neurotrophic and neuroprotective research [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 138764-85-9. Pack Sizes: 500 μg; 5 mg; 10 mg. Product ID: HY-P1845.
PACAP (6-27) (human, ovine, rat)
PACAP (6-27) (human, ovine, rat) is a PACAP receptor antagonist that blocks the canine adrenal catecholamine response to exogenous vasoactive intestinal peptide (VIP). PACAP (6-27) (human, ovine, rat) has the potential to study cardiovascular and neurological diseases [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Pituitary adenylate cyclase-activating peptide (6-27). CAS No. 136134-68-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3117.
PACAP (6-38), human, ovine, rat TFA
PACAP (6-38), human, ovine, rat TFA is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptor VIP1, and PACAP type II receptor VIP2, respectively. Uses: Scientific research. Group: Peptides. Pack Sizes: 500 ?g; 1 mg; 5 mg. Product ID: HY-P0220A.
Pachypodol
Pachypodol exerts antioxidant and cytoprotective effects in HepG2 cells [1].Pachypodol inhibits the growth of CaCo 2 colon cancer cell line in vitro( IC 50 = 185.6 mM) [2]. Uses: Scientific research. Group: Natural products. CAS No. 33708-72-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N3121.
Paclitaxel
Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 33069-62-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0015.
Paclitaxel (Standard)
Paclitaxel (Standard) is the analytical standard of Paclitaxel. This product is intended for research and analytical applications. Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 33069-62-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0015R.
Paclobutrazol
Paclobutrazol is a triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins. Paclobutrazol also has antifungal activities. Paclobutrazol, transported acropetally in plants, can also suppress the synthesis of abscisic acid and induce chilling tolerance in plants. Paclobutrazol is typically used to support research on the role of gibberellins in plant biology [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 76738-62-0. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-B0853.
PACMA 31
PACMA 31 is an irreversible, orally active protein disulfide isomerase (PDI) inhibitor with an IC50 of 10 ?M. PACMA 31 forms a covalent bond with the active site cysteines of PDI. PACMA 31 shows tumor targeting ability and significantly suppresses ovarian tumor growth without causing toxicity to normal tissues[1]. PACMA 31 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1401089-31-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100433.
Pacmilimab
Pacmilimab (CX-072) is a potent PD-L1 inhibitor. Pacmilimab shows antitumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CX-072. CAS No. 2145091-51-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99799.
Pacritinib
Pacritinib (SB1518) is a potent inhibitor of both wild-type JAK2 (IC 50 =23 nM) and JAK2 V617F mutant (IC 50 =19 nM). Pacritinib also inhibits FLT3 (IC 50 =22 nM) and its mutant FLT3 D835Y (IC 50 =6 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB1518. CAS No. 937272-79-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16379.
Padnarsertib
Padnarsertib (KPT-9274) is an orally bioavailable, dual PAK4/Nicotinamide phosphoribosyltransferase (Nampt) inhibitor, with IC50s of <100 nM and 120 nM, respectively[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KPT-9274. CAS No. 1643913-93-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12793.
Padsevonil
Padsevonil (UCB0942) is a potent antiepileptic agent that selectively acts on presynaptic and postsynaptic targets. Padsevonil binds to synaptic vesicular protein 2 ( SV2 ) with high affinity. Padsevonil is also a positive allosteric modulator and partial agonist of GABA A R , with high potency against α1 and α5 receptors. Padsevonil has antiepileptic effects in a variety of rodent models [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UCB-0942. CAS No. 1294000-61-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109009.
Paederosidic acid
Paederosidic acid is isolated from P. scandens with anticancer and anti?inflammation activities. Paederosidic acid inhibits lung caner cells via inducing mitochondria-mediated apoptosis [1]. Uses: Scientific research. Group: Natural products. CAS No. 18842-98-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N6998.
Paeoniflorgenin
Paeoniflorgenin is a deglucosylated metabolite of Paeoniflorin [1]. Uses: Scientific research. Group: Natural products. CAS No. 697300-41-7. Pack Sizes: 1 mg. Product ID: HY-N7686.
Paeoniflorin
Paeoniflorin is a heat shock protein -inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Peoniflorin. CAS No. 23180-57-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-N0293.
Paeonol
Paeonol is an active extraction from the root of Paeonia suffruticosa , Paeonol inhibits MAO-A and MAO-B with IC 50 of 54.6 μM and 42.5 μM, respectively. Uses: Scientific research. Group: Natural products. CAS No. 552-41-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N0159.
Pafolacianine
Pafolacianine (OTL 38) is a fluorescent imaging agent made of near-infrared dye used in detecting tumor lesions during surgical procedures. Pafolacianine excites at 774 to 775?nm and emits at 794 to 796?nm [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: OTL 38. CAS No. 1628423-76-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-139579.
Pafuramidine
Pafuramidine (DB289) is an orally active proagent of Furamidine (HY-110137A). Pafuramidine is a potent anti-parasitic agent, can be used to research trypanosomiasis, Pneumocystis pneumonia and malaria [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DB289. CAS No. 186953-56-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14932.
Pagibaximab
Pagibaximab is a chimeric IgG1 antibody recognizing the surface component lipoteichoic acid of S. aureus and S. epidermidis. Pagibaximab can be used to prevent staphylococcal sepsis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BSYX-A 110; Anti-S. Epidermidis LTA Recombinant Antibody. CAS No. 595566-61-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99309.
Pagoclone
Pagoclone is an active (+)-enantiomer of the racemate RP 59037. Pagoclone is a partial GABA(A) receptor agonist used for the treatment of panic and anxiety disorders. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-RP-59037; IP-456; RP-62955. CAS No. 133737-32-3. Pack Sizes: 2 mg; 5 mg; 10 mg. Product ID: HY-101665.
Palacaparib
AZD-9574 is a potent and brain penetrant PARP1 inhibitor and shows >8000-fold selectivity for PARP1 compared to PARP2/3/5a/6. AZD-9574 acts by selectively inhibiting and trapping PARP1 at the sites of SSBs. AZD-9574 is an anti-cancer agent and can be used for HRD+?breast cancer and advanced solid malignancies research[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD-9574. CAS No. 2756333-39-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145804.
Palazestrant
Palazestrant is an antiestrogen and antineoplastic agent. Palazestrant can completely inhibit the activity of 17b-estradiol (E2) with IC 50 value of 6.4 nM, and inhibit the proliferation of MCF7 and CAMA-1 cells with IC 50 value of 1.4-1.6 nM. Palazestrant can inhibit ER + /HER2 + cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OP-1250. CAS No. 2092925-89-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148789.
Palbociclib
Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC 50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma [1] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD 0332991. CAS No. 571190-30-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50767.
Palbociclib hydrochloride
Palbociclib (PD 0332991) hydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC 50 values of 11 and 16 nM, respectively. Palbociclib hydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells. Palbociclib hydrochloride can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma [1] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD-0332991 hydrochloride. CAS No. 571189-11-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50767C.
Palbociclib isethionate
Palbociclib (PD 0332991) isethionate is an orally active selective CDK4 and CDK6 inhibitor with IC 50 values of 11 and 16 nM, respectively. Palbociclib isethionate has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma [1] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD 0332991 isethionate. CAS No. 827022-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-A0065.
Palbociclib monohydrochloride
Palbociclib (PD 0332991) monohydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib monohydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma[1][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD 0332991 monohydrochloride. CAS No. 827022-32-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-50767A.
Palbociclib (Standard)
Palbociclib (Standard) is the analytical standard of Palbociclib. This product is intended for research and analytical applications. Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma[1][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD 0332991 (Standard). CAS No. 571190-30-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50767R.
Palifosfamide
Palifosfamide is a novel DNA alkylator and the active metabolite of ifosfamide, with antitumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Isophosphoramide mustard; IPM; ZIO-201. CAS No. 31645-39-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14798.
Paliperidone
Paliperidone (9-Hydroxyrisperidone), the major active metabolite of Risperidone, is a dopamine D2 antagonist and 5-HT2A antagonist. Paliperidone is also active as an antagonist at α1 and α2 adrenergic receptors and H1-histaminergic receptors. Paliperidone, a antipsychotic agent, shows efficacy against schizophrenia [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 9-Hydroxyrisperidone. CAS No. 144598-75-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-A0019.
Paliperidone palmitate
Paliperidone palmitate (9-Hydroxyrisperidone palmitate), an atypical long-acting antipsychotic agent, is an ester proagent of Paliperidone. Paliperidone is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class. Paliperidone palmitate shows efficacy against schizophrenia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9-Hydroxyrisperidone palmitate. CAS No. 199739-10-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0019A.
Palivizumab
Palivizumab (MEDI 493) is a humanized monoclonal antibody against respiratory syncytial virus ( RSV ). Palivizumab can bind to RSV F protein with a K d value of 1.4 nM. Palivizumab can prevent respiratory syncytial virus infection in cotton mice [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI 493. CAS No. 188039-54-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9944.
Palladium(?) acetylacetonate
Palladium(?) acetylacetonate (Palladium(?) 2,4-pentanedionate; Pd(acac)2) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Palladium(?) 2,4-pentanedionate; Pd(acac)2. CAS No. 14024-61-4. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W020952.
Palladium (II) acetate
Palladium (II) acetate is a catalyst that catalyzes aromatic substitution reactions [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 3375-31-3. Pack Sizes: 250 mg; 1 g. Product ID: HY-W002072.
Palladium trifluoroacetate
Palladium (trifluoroacetate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 42196-31-6. Pack Sizes: 250 mg; 1 g. Product ID: HY-W007333.
Pallidol
Pallidol is a potent and selective singlet oxygen quencher. Pallidol shows antioxidant and antifungal activities [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1622292-61-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-117245.
Palmatine chloride
Palmatine chloride is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC 50 s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine chloride can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC 50 of 96 μM. Palmatine chloride shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 10605-02-4. Pack Sizes: 10 mM * 1 mL; 250 mg; 1 g. Product ID: HY-N0110.
Palmatine hydroxide
Palmatine hydroxide is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC 50 s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine hydroxide can also inhibit West Nile virus (WNV) NS2B-NS3 protease in an uncompetitive manner with an IC 50 of 96 μM. Palmatine hydroxide shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 131-04-4. Pack Sizes: 10 mM * 1 mL; 250 mg; 1 g. Product ID: HY-N0110B.
Palmitelaidic acid-d13
Palmitelaidic acid-d 13 is the deuterium labeled Palmitelaidic Acid. Palmitelaidic Acid (9-trans-Hexadecenoic acid) is the trans isomer of palmitoleic acid. Palmitoleic acid is one of the most abundant fatty acids in serum and tissue. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 2692623-91-7. Pack Sizes: 1 mg (37.38 mM * 100 μL in Ethanol). Product ID: HY-N2341S.