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QTZ
QTZ is a bioluminescence agent for in vivo imaging. QTZ has red-shifted emission and yields very little background. QTZ is a coelenterazine analog with the 4-quinolinyl substitution at the C8 position of the imidazopyrazinone core [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2883232-39-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-47176.
Quabodepistat
Quabodepistat (OPC-167832) is a potent and orally active dprE1 inhibitor with an IC 50 of 0.258 μM. Quabodepistat has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC-167832. CAS No. 1883747-71-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134940.
Quarfloxin
Quarfloxin (CX-3543), a fluoroquinolone derivative with antineoplastic activity, targets and inhibits RNA pol I activity, with IC 50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA (rDNA) template [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CX-3543. CAS No. 865311-47-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14776.
Quassin
Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC 50 of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Nigakilactone D. CAS No. 76-78-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1581.
Quavonlimab
Quavonlimab (MK-1308) is a novel anti- CTLA-4 antibody [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MK-1308. CAS No. 2254059-25-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99809.
Quazinone
Quazinone is a selective inhibitor of cGMP-inhibited-phosphodiesterase ( cGI-PDE, PDE3 ). Quazinone inhibits the phosphorylation of p42/p44 MAP kinase. Quazinone possesses antimitogenic effect [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 13-6438; Ro 13-6438/006. CAS No. 70018-51-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-106477.
Quercetagetin
Quercetagetin (6-Hydroxyquercetin) is a flavonoid [1]. Quercetagetin is a moderately potent and selective, cell-permeable pim-1 kinase inhibitor ( IC 50 , 0.34 μM) [2]. Anti-inflammatory and anticancer properties. Uses: Scientific research. Group: Natural products. Alternative Names: 6-Hydroxyquercetin. CAS No. 90-18-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N4149.
Quercetin
Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC 50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively [1]. Uses: Scientific research. Group: Natural products. CAS No. 117-39-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-18085.
Quercetin-3'-O-glucoside
Quercetin-3'-O-glucoside is a flavonol, which can be isolated from the flowers of Quercetin. Quercetin-3'-O-glucoside modulates Alloxan (HY-W017227)-induced hyperglycemia and lipid peroxidation (LPO) in rats, exerting anti-diabetic and anti-peroxidation effects. Quercetin-3'-O-glucoside improves diabetes and tissue lipid peroxidation by virtue of its insulin-stimulating and/or free radical-scavenging properties [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 19254-30-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N12445.
Quercetin dihydrate
Quercetin dihydrate, a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC 50 s of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively [1]. Uses: Scientific research. Group: Natural products. CAS No. 6151-25-3. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N0146.
Quercetin hydrate
Quercetin hydrate, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC 50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 849061-97-8. Pack Sizes: 500 mg. Product ID: HY-18085A.
Quercitrin
Quercitrin (Quercetin 3-rhamnoside) is a bioflavonoid compound with potential anti-inflammation, antioxidative and neuroprotective effect. Quercitrin induces apoptosis of colon cancer cells. Quercitrin can be used for the research of cardiovascular and neurological disease research [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Quercetin 3-rhamnoside. CAS No. 522-12-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0418.
Questiomycin A
Questiomycin A (Phx-3) is a GRP78 (cytoprotective endoplasmic reticulum chaperone) degrader and enhances the anticancer activity of Sorafenib. Questiomycin A is also an antimicrobial/antibiotic that can be obtained from the metabolite of Pseudomonas chlororaphis HT66. Questiomycin A can be used in research on biological control of cancer and plant diseases [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Phx-3. CAS No. 1916-59-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8439.
Quetiapine
Quetiapine (ICI204636) is a 5-HT receptors agonist with a pEC 50 of 4.77 for human 5-HT1A receptor. Quetiapine is a dopamine receptor antagonist with a pIC 50 of 6.33 for human D2 receptor. Quetiapine has moderate to high affinity for the human D2 , HT1A , 5-HT2A , 5-HT2C receptor with pK i s of 7.25, 5.74, 7.54, 5.55. Antidepressant and anxiolytic effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICI204636. CAS No. 111974-69-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14544.
Quetiapine hemifumarate
Quetiapine hemifumarate is a 5-HT receptors agonist with a pEC 50 of 4.77 for human 5-HT1A receptor. Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC 50 of 6.33 for human D2 receptor. Quetiapine hemifumarate has moderate to high affinity for the human D2 , HT1A , 5-HT2A , 5-HT2C receptor with pK i s of 7.25, 5.74, 7.54, 5.55. Antidepressant and anxiolytic effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 111974-72-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0031.
Quetiapine sulfoxide dihydrochloride
Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide dihydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic [1]. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Quetiapine S-oxide dihydrochloride. CAS No. 329218-11-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-G0014A.
Queuine
Queuine is a hypermodified nucleobase , which is modified to queuosine. Queuine, as an important micronutrient, can be used for the research of diseases associated with human gut microbiome [1]. Uses: Scientific research. Group: Natural products. CAS No. 72496-59-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N10574.
Queuine dihydrochloride
Queuine dihydrochloride is a super-modified nucleobase, modified to queuosine dihydrochloride. Queuine dihydrochloride is an important micronutrient that can be used in the study of human intestinal microbial-related diseases [1]. Uses: Scientific research. Group: Natural products. CAS No. 86496-18-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N10574A.
Quilizumab
Quilizumab (Anti-Human IGHE Recombinant Antibody) is a humanized IgG1κ monoclonal antibody targeting immunoglobulin epsilon (also konwn as: IGHE, IgE). Quilizumab targets the M1-prime fragment of membrane-expressed IGHE/IgE , leading to IGHE/IgE switching and memory B cell depletion. Quilizumab has potential in asthma research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human IGHE Recombinant Antibody. CAS No. 1228538-47-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99313.
Quillaic acid
Quillaic acid (Quillaja sapogenin)It is an anti-gastric cancer and anti-proliferation agent that can promote apoptosis of cancer cells. (apoptosis). Quillaic acidAlso has analgesic and local anti-inflammatory activity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Quillaja sapogenin. CAS No. 631-01-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0839.
Quinacrine
Quinacrine (Acriquine) is an antimalarial and anti-cancer agent. Quinacrine also inhibits human aldehyde oxidase ( IC 50 : 3.3 μM). Quinacrine has affinity for nucleic acids, and stains DNA and RNA in fixed cells (Ex/Em: 436/525 nm) [1] [2] [3] [4] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Acriquine. CAS No. 83-89-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13735.
Quinacrine dihydrochloride
Quinacrine (Mepacrine) dihydrochloride is an orally bioavailable antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine dihydrochloride suppresses NF-κB and activate p53 signaling, which results in the induction of the apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mepacrine dihydrochloride; SN-390 dihydrochloride. CAS No. 69-05-6. Pack Sizes: 100 mg. Product ID: HY-13735A.
Quinacrine hydrochloride hydrate
Quinacrine hydrochloride hydrate (Mepacrine hydrochloride hydrate) is an antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine hydrochloride hydrate suppresses NF-κB and activates p53 signaling, which results in the induction of the apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mepacrine hydrochloride hydrate; SN-390 hydrochloride hydrate. CAS No. 6151-30-0. Pack Sizes: 100 mg. Product ID: HY-13735B.
Quinacrine mustard dihydrochloride
Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 4213-45-0. Pack Sizes: 5 mg. Product ID: HY-W127705.
Quinagolide hydrochloride
Quinagolide hydrochloride (CV205-502 hydrochloride) is a selective and orally active dopamine D2 receptor agonist. Quinagolide hydrochloride is an inhibitor of prolactin. Quinagolide hydrochloride down-regulates AKT levels and its phosphorylation. Quinagolide hydrochloride shows antitumor effects, it can be used for the research of cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CV205-502 hydrochloride. CAS No. 94424-50-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13736A.
Quinalizarin
Quinalizarin is a potent, selective and cell-permeable protein kinase CK2 inhibitor with an K i of ~50 nM and an IC 50 of 110 nM. Quinalizarin can induce apoptosis of certain cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81-61-8. Pack Sizes: 5 mg. Product ID: HY-124833.
Quinapril hydrochloride
Quinapril (hydrochloride) (CI-906) is a proagent that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI-906. CAS No. 82586-55-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0477.
Quinelorane dihydrochloride
Quinelorane dihydrochloride (LY163502) is a potent dopamine D3/D2 receptor agonist. Quinelorane has the potential for neurological and psychiatric disorders research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY163502. CAS No. 97548-97-5. Pack Sizes: 5 mg. Product ID: HY-103429.
Quinestrol
Quinestrol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: W-3566. CAS No. 152-43-2. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-B1012.
Quinfamide
Quinfamide is an antiamebic agent. Quinfamide has the potential to treat tropical parasitic infections such as Amoebiasis and Helminthiasis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WIN-40014. CAS No. 62265-68-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-119826.
Quinidine hydrochloride monohydrate
Quinidine hydrochloride monohydrate is an anti-arrythmic agent which is also a potent blocker of K + channel with an IC 50 of 19.9 μM. Uses: Scientific research. Group: Natural products. CAS No. 6151-40-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1302.
Quinine
Quinine is an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine is a potassium channel inhibitor that inhibits WT mouse Slo3 (K Ca 5.1) channel currents evoked by voltage pulses to +100?mV with an IC 50 of 169 μM [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 130-95-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-D0143.
Quinine hemisulfate hydrate
Quinine hemisulfate hydrate, an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine hemisulfate hydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (K Ca 5.1) channel currents evoked by voltage pulses to +100?mV, with an IC 50 of 169 μM [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 207671-44-1. Pack Sizes: 1 g. Product ID: HY-D0143B.
Quinine hydrochloride dihydrate
Quinine hydrochloride dihydrate (Qualaquin) is an orally active and can be used in anti-malarial studies. Quinine hydrochloride dihydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (K Ca 5.1) channel currents evoked by voltage pulses to +100?mV with an IC 50 of 169 μM [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 6119-47-7. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-B0433A.
Quinine sulfate
Quinidine sulfate is an antiarrhythmic agent. Quinidine sulfate is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine sulfate is also a K + channel blocker with an IC 50 of 19.9 μM. Quinidine sulfate can be used for malaria research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 549-56-4. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B1751B.
Quinine sulfate hydrate
Quinine sulfate hydrate (2:1:4) is an orally active alkaloid extracted from cinchona bark and can be used in anti-malarial studies. Quinine sulfate hydrate (2:1:4) is a potassium channel inhibitor that inhibits WT mouse Slo3 (K Ca 5.1) channel currents evoked by voltage pulses to +100 mV with an IC 50 of 169 μM [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 6119-70-6. Pack Sizes: 25 g; 50 g. Product ID: HY-W010668.
Quinizarin
Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode ( K d =86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 1,4-Dihydroxyanthraquinone. CAS No. 81-64-1. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-D0226.
Quinoline-2-carboxaldehyde
Quinoline-2-carboxaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 2-Quinolinecarboxaldehyde; Quinoline-2-carboxaldehyde. CAS No. 5470-96-2. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-W008168.
Quinoline-2-carboxylic acid
Quinoline-2-carboxylic acid is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 93-10-7. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W002011.
Quinoline-8-carboxylic acid
Quinoline-8-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 86-59-9. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W007371.
Quinolinic acid
Quinolinic acid is an endogenous N-methyl-D-aspartate ( NMDA ) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 89-00-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 10 g. Product ID: HY-100807.
Quinoxyfen
Quinoxyfen (DE-795) is a powdery mildew fungicide [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DE-795. CAS No. 124495-18-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-120734.
Quinpirole hydrochloride
Quinpirole hydrochloride (LY 171555 hydrochloride) is a high-affinity agonist of dopamine D2/D3 receptor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY 171555 hydrochloride; (-)-LY 141865 hydrochloride. CAS No. 85798-08-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1752A.
Quinupristin
Quinupristin is a streptogramin antibiotic. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 120138-50-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-A0162.
Quipazine
Quipazine is a 5-HT agonist with a K i value of 1.4 nM for displaces [3H]GR65630 from 5-HT3R in rat. Quipazine shows antiviral activity against SARS-CoV-2 with an EC 50 of 31.64 μM. Quipazine behaves as a 5-HT3R agonist in peripheral models. Quipazine can be used for neurological disease research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4774-24-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W028142.
Quisinostat
Quisinostat (JNJ-26481585) is a potent, second-generation and orally active pan- HDAC inhibitor (HDACi), with IC 50 values ranging from 0.11 nM to 0.64 nM for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11. Quisinostat has a broad spectrum antitumoral activity [1]. Quisinostat can induce autophagy in neuroblastoma cells [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-26481585. CAS No. 875320-29-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15433.
Quisinostat dihydrochloride
Quisinostat dihydrochloride (JNJ-26481585 dihydrochloride) is an orally available, potent pan- HDAC inhibitor with IC 50 s of 0.11 nM, 0.33 nM, 0.64 nM, 0.46 nM, and 0.37 nM for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11, respectively. Quisinostat dihydrochloride has a broad spectrum antitumoral activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-26481585 dihydrochloride. CAS No. 875320-31-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-15433A.
Quisovalimab
Quisovalimab (AVTX-002; AEVI 002; SAR 252067) is a human monoclonal antibody against LIGHT , a tumor necrosis factor (TNF)-related cytokine (TNFSF14) that plays an important role in acute respiratory distress syndrome (ARDS) and cytokine release syndrome (CRS) COVID-19. Quisovalimab can be used in COVID-19 acute respiratory distress syndrome and other studies [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AVTX-002; AEVI 002; SAR 252067. CAS No. 2427667-03-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99810.
Quisqualic acid
Quisqualic acid (L-Quisqualic acid), a natural analog of glutamate, is a potent and pan two subsets ( iGluR and mGluR ) of excitatory amino acid (EAA) agonist with an EC 50 of 45 nM and a K i of 10 nM for mGluR1R. Quisqualic acid is isolated from the fruits of Quisqualis indica [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: L-Quisqualic acid. CAS No. 52809-07-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-12597.
Quizartinib
Quizartinib (AC220) is an orally active, highly selective and potent second-generation type II FLT3 tyrosine kinase inhibitor, with a K d of 1.6 nM. Quizartinib inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in MV4-11 cells with IC 50 s of 4.2 and 1.1 nM, respectively. Quizartinib can be linked to the VHL ligand via an optimized linker to form a PROTAC FLT3 degrader. Quizartinib induces apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AC220; AC708. CAS No. 950769-58-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13001.
Quizartinib dihydrochloride
Quizartinib dihydrochloride (AC220 dihydrochloride) is the dihydrochloride salt form of Quizartinib (HY-13001). Quizartinib dihydrochloride is an orally active, highly selective and potent second-generation type II FLT3 tyrosine kinase inhibitor, with a K d of 1.6 nM. Quizartinib dihydrochloride inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in MV4-11 cells with IC 50 s of 4.2 and 1.1 nM, respectively. Quizartinib dihydrochloride can be linked to the VHL ligand via an optimized linker to form a PROTAC FLT3 degrader. Quizartinib dihydrochloride induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AC220 dihydrochloride. CAS No. 1132827-21-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14217.
QX-314 bromide
QX-314 bromide is a membrane-impermeable permanently charged sodium channel blocker [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24003-58-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-101350.
QX-314 chloride
QX-314 chloride is a membrane-impermeable permanently charged sodium channel blocker [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5369-3-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-108505.
R110
R110 is a potent, competitive inhibitor of macrophage migration inhibitory factor 2 (MIF2) tautomerase with an IC 50 of 15 μM. R110 has the potential for the research of cancer diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1985622-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115887.
R112
R112 is a fast and reversible inhibitor of spleen tyrosine kinase ( Syk ) kinase. R112 inhibits Syk kinase activity with an IC 50 value of 226 nM and a Ki value of 96 nM. R112 inhibits IgE-FcεRI signaling pathway. R112 can be used for the research of allergic rhinitis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 575474-82-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16420.
(R)-[1,1'-Binaphthalene]-2,2'-diamine
(R)-[1, 1'-Binaphthalene]-2, 2'-diamine is the isomer of (S)-[1, 1'-Binaphthalene]-2, 2'-diamine (HY-W007978A), and can be used as an experimental control. (S)-[1, 1'-Binaphthalene]-2, 2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-(-)-2,2-Diamino-1,1-binaphthyl. CAS No. 18741-85-0. Pack Sizes: 250 mg; 1 g; 5 g. Product ID: HY-W007978.
(R)-1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate
(R)-(-)-1,1'-Binaphthyl-2,2'-diyl Hydrogenphosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 39648-67-4. Pack Sizes: 10 g; 25 g. Product ID: HY-I0718.
(R)-(-)-1,2-Propanediol
(R)-(-)-1,2-Propanediol is a (R)-enantiomer of 1,2-Propanediol that produced from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes [1]. Uses: Scientific research. Group: Natural products. CAS No. 4254-14-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Z0031.
(R)-(-)-1,3-Butanediol
(R)-(-)-1,3-Butanediol is the R-enantiomer of 1,3-Butanediol (HY-77490A). (R)-(-)-1,3-Butanediol exhibits anti-diabetic property in rats. (R)-(-)-1,3-Butanediol can be used as flavoring and fragrance agents. (R)-(-)-1,3-Butanediol is used to regulate the metabolism of carbohydrate and lipid. [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 6290-3-5. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-77490.
(R)-1-Amino-2-propanol
(R)-1-aminopropan-2-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2799-16-8. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-W002295.
(R)-1-Boc-3-aminopyrrolidine
(R)-1-Boc-3-aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 147081-49-0. Pack Sizes: 5 g; 10 g. Product ID: HY-40097.
(R)-1-Boc-3-methyl-piperazine
(R)-1-Boc-3-methyl-piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 163765-44-4. Pack Sizes: 25 g. Product ID: HY-40041.
R-1 Methanandamide Phosphate
R-1 Methanandamide Phosphate is a water-soluble prodrug analog of arachidonylethanolamide (AEA). AEA is an endogenous cannabinoid compound [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 649569-33-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-126719.
(R,1R)-Tenofovir amibufenamide
(R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) can be used for the purifying a tenofovir prodrug. Tynofovir (tenofovir) is a nucleoside acids reverse transcriptase inhibitors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R,1R)-HS-10234. CAS No. 1571076-37-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-137453C.
(R)-(-)-2-Butanol
(R)-(-)-2-Butanol is the isomer of 2-Butanol, which is found in the females of the white grub beetle, Dasylepida ishigakiensis , to attract males. (R)-(-)-2-Butanol is an intermediate of pharmaceutical synthesis by coupling [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 14898-79-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W087952.
(R)-2-Methylpiperazine
(R)-(-)-2-Methylpiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 75336-86-6. Pack Sizes: 25 g. Product ID: HY-34767.
(R)-3-(Boc-amino)pyrrolidine
tert-butyl N-[(3R)-pyrrolidin-3-yl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 122536-77-0. Pack Sizes: 5 g; 10 g. Product ID: HY-W002421.
(R)-3-Fluoropyrrolidine hydrochloride
(R)-3-Fluoropyrrolidine hydrochloride is a derivative of fluorinated pyrrolidines. The amide series of fluorinated pyrrolidines are inhibitors of dipeptidyl peptidase DP-IV. Novel α4β2 receptor ligands characterized by a 3-Fluoropyrrolidine core [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 136725-55-8. Pack Sizes: 1 g; 5 g. Product ID: HY-40421.
(R)-3-Hydroxybutanoic acid
(R)-3-Hydroxybutanoic acid is a metabolite, and converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid has applications as a nutrition source and as a precursor for vitamins, antibiotics and pheromones [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-(-)-3-Hydroxybutanoic acid; (R)-3-Hydroxybutyric acid. CAS No. 625-72-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W051723.
(R)-3-Hydroxybutanoic acid sodium
(R)-3-Hydroxybutanoic acid ((R)-3-Hydroxybutyric acid) sodium is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-(-)-3-Hydroxybutanoic acid sodium; (R)-3-Hydroxybutyric acid sodium. CAS No. 13613-65-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W015851.