MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| N-Ethyl-N-nitrosourea | N-Ethyl-N-nitrosourea (ENU) is a DNA alkylating agent. N-Ethyl-N-nitrosourea induces leukemia by alkylating nucleobases, disrupting DNA, and resulting in bone marrow suppression and the formation of leukemic cells. N-Ethyl-N-nitrosourea is teratogenic in vivo, inducing tumor formation and paw malformations in pregnant rats. N-Ethyl-N-nitrosourea cause central nervous system (CNS) tumors and genetic disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ENU; N-Nitroso-N-ethylurea. CAS No. 759-73-9. Pack Sizes: 250 mg; 1 g; 5 g; 10 g. Product ID: HY-W019815. |  |
| Neticonazole | Neticonazole is an imidazole derivative and a potent and long-acting antifungal agent. Neticonazole has anti-infection and anti-cancer effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130726-68-0. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-106541. | |
| Neticonazole hydrochloride | Neticonazole hydrochloride is an imidazole derivative and a potent and long-acting antifungal agent. Neticonazole hydrochloride has anti-infection and anti-cancer effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130773-02-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-128365. | |
| Netilmicin sulfate | Netilmicin (sulfate) (SCH-20569 (sulfate)) is an active aminoglycoside antibiotic against most Gram-negative and some Gram-positive bacteria, including certain strains resistant to gentamicin. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH-20569 sulfate. CAS No. 56391-57-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0086. | |
| Netoglitazone | Netoglitazone is a dual agonist of PPARα and PPARγ with antihyperglycemic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCC-555; Isaglitazone. CAS No. 161600-01-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100428. | |
| Netropsin dihydrochloride | Netropsin dihydrochloride is a small-molecule MGB (minor-groove binder) and antibiotic, inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nuclei. Netropsin dihydrochloride has antibacterial and antiviral activity [1] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 18133-22-7. Pack Sizes: 1 mg. Product ID: HY-N6800A. | |
| Netupitant | Netupitant (CID-6451149) is a highly potent, selective and orally active neurokinin-1 (NK 1 ) receptor antagonist with a K i of 0.95 nM for hNK 1 in CHO cells. Netupitant has antiemetic affect [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CID 6451149. CAS No. 290297-26-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16346. | |
| Neuraminidase, Microorganism | Neuraminidase, Microorganism (Exo-α-sialidase) is an exosialidase, is often used in biochemical studies. Neuraminidase cleaves α-ketosidic linkage between the sialic (N-acetylneuraminic) acid and an adjacent sugar residue. Neuraminidase, derived from mucosal pathogens, is a virulence factor that modifies the host's response to infection [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Exo-α-sialidase. CAS No. 9001-67-6. Pack Sizes: 5 U; 10 U. Product ID: HY-P2988. | |
| Neurodazine | Neurodazine is a neurogenic inducer , serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways. [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 937807-66-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108439. | |
| Neurokinin A | Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Substance K; Neurokinin α; Neuromedin L. CAS No. 86933-74-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0197. | |
| Neurokinin A TFA | Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Substance K TFA; Neurokinin α TFA; Neuromedin L TFA; NKA TFA. CAS No. 2828433-19-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0197A. | |
| Neurokinin B TFA | Neurokinin B TFA belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect [1]. Uses: Scientific research. Group: Peptides. CAS No. 101536-55-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0242A. | |
| Neuromedin B | Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals. Uses: Scientific research. Group: Peptides. CAS No. 87096-84-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0241. | |
| Neuromedin C (porcine) | Neuromedin C porcine (GRP, 18-27, porcine) is a bombesin-like neuropeptide that can be obtained from porcine spinal cord. Neuromedin C porcine exhibits a potent contractile activity on rat uterus in the characteristic manner of bombesin. Neuromedin C porcine has research potential for neurological-related diseases [1]. Uses: Scientific research. Group: Peptides. Alternative Names: GRP(18-27) (porcine). CAS No. 81608-30-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-103283. | |
| Neuromedin N | Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Uses: Scientific research. Group: Peptides. Alternative Names: Neuromedin N (rat, mouse, porcine, canine). CAS No. 92169-45-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-P0079. | |
| Neuromedin U-25 (porcine) | Neuromedin U-25 (porcine) is a uterus stimulating and hypertensive peptides [1]. Uses: Scientific research. Group: Peptides. CAS No. 98395-76-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4682. | |
| Neuropeptide FF | Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, interacts with two distinct G-protein-coupled receptors, NPFF(1) and NPFF(2) and has wide variety of physiological functions in the brain including central cardiovascular and neuroendocrine regulation [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: NPFF. CAS No. 99566-27-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1248. | |
| Neuropeptide SF (human) | Neuropeptide SF human augments paraventricular corticotrophin-releasing hormone (CRH) release and increases adrenocorticotropic hormone (ACTH) and corticosterone levels in the plasma. Neuropeptide SF human play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Neuropeptide NPFF (human). CAS No. 192387-39-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1245. | |
| Neuropeptide S (mouse) | Neuropeptide S (mouse) is a bioactive peptide. Neuropeptide S (mouse), as a neurotransmitter/neuromodulator of 20 amino acids, can be used for the research of arousal, anxiety, locomotion, feeding behaviors, memory and agent addiction [1]. Uses: Scientific research. Group: Peptides. CAS No. 412938-74-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1437. | |
| Neuropeptide W-23 (human) | Neuropeptide W-23 (human) (NPW-23), the active form of Neuropeptide W, is an endogenous agonist of NPBW1 (GPR7) and NPBW2 (GPR8) [1]. Uses: Scientific research. Group: Peptides. Alternative Names: NPW-23. CAS No. 383415-79-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1035. | |
| Neuropeptide Y (13-36), porcine | Neuropeptide Y (13-36), porcine is a selective neuropeptide Y 2 receptor agonist [1]. Uses: Scientific research. Group: Peptides. Alternative Names: NPY 13-36. CAS No. 113662-54-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1011. | |
| Neuropeptide Y (human,rat,mouse) | Neuropeptide Y (human,rat,mouse) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity. Uses: Scientific research. Group: Peptides. Alternative Names: Neuropeptide Y (29-64), amide. CAS No. 90880-35-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0198. | |
| Neurotensin | Neurotensin, a gut tridecapeptide, acts as a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinity neurotensin receptors ( NTR ). Uses: Scientific research. Group: Peptides. CAS No. 39379-15-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0234. | |
| Neurotensin(8-13) | Neurotensin (8-13) is an active fragment of Neurotensin. Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. Uses: Scientific research. Group: Peptides. CAS No. 60482-95-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0251. | |
| Neutral protease I | Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dispase I. CAS No. 42613-33-2. Pack Sizes: 1 mg. Product ID: HY-131577A. | |
| Neutral Red | Neutral Red, a nitrogenous pH-indicator with a pK i of 6.8, is an indicator for the internal acidification of thylakoids. Neutral Red stains lysosomes red [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 553-24-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-D0166. | |
| Neutrophil elastase inhibitor 1 | Neutrophil elastase inhibitor 1 (Compound 5b) is a competitive, pseudoirreversible inhibitor for neutrophil elastase with an IC 50 of 7 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1448314-31-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-118177. | |
| Nevirapine | Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a K i of 270 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI-RG 587; NSC 641530; NVP. CAS No. 129618-40-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10570. | |
| NF110 | NF110 is a P2X 3 receptor antagonist ( K i=36 nM) and inactive toward P2Y receptors stably expressed (IC 50 s > 10 M). NF110 blocks alphabeta-methylene-ATP-induced currents (IC 50 = 527 nM) in rat dorsal root ganglia neurons [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 111150-22-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108671. | |
| NF279 | NF279 is a potent selective and reversible P2X1 receptor antagonist, with an IC 50 of 19 nM. NF279 displays good selectivity over P2X2, P2X3 (IC 50=1.62 μM), P2X4 (IC 50 >300 μM). NF279 is a dual HIV-1 coreceptor inhibitor that interferes with the functional engagement of CCR5 and CXCR4 by Env [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 202983-32-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D0976. | |
| NF-κB-IN-11 | NF-κB-IN-11 (Compound 3i) is a NF-κB inhibitor. NF-κB-IN-11 inhibits TNF-α induced activation of NF-κB pathway, and inhibits nuclear translocation of NF-κB. NF-κB-IN-11 down-regulates the expression levels of phosphor-IKK, IκBα, and NF-κB p65. NF-κB-IN-11 has anti-inflammatory activity, and alleviates dextran sulfate sodium-induced colitis in mice. NF-κB-IN-11 (p.o.) shows a MTD more than 1852 mg/kg in mice acute toxicity assay [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768833-35-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155998. | |
| N-Formylcytisine | N-Formylcytisine is a cytisine-type alkaloid from the stem bark of Maackia amurensis [1]. Uses: Scientific research. Group: Natural products. CAS No. 53007-06-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7625. | |
| N-Formylglycine | N-Formylglycine is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 2491-15-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-128735. | |
| N-Formyl-Met-Leu-Phe | N-Formyl-Met-Leu-Phe (fMLP; N-Formyl-MLF) is a chemotactic peptide and a specific ligand of N-formyl peptide receptor (FPR). N-Formyl-Met-Leu-Ph is reported to inhibit TNF-alpha secretion. Uses: Scientific research. Group: Peptides. Alternative Names: fMLP; N-Formyl-MLF. CAS No. 59880-97-6. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-P0224. | |
| N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys | N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist [1]. Uses: Scientific research. Group: Peptides. Alternative Names: For-Nle-Leu-Phe-Nle-Tyr-Lys-OH. CAS No. 71901-21-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1591. | |
| N-Glycolylneuraminic acid | N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: NeuGc; GcNeu. CAS No. 1113-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-128965. | |
| NGM-120 | NGM-120 is a CHO-expressed human antibody that targets GFRAL. NGM-120 contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145.7 kDa. The isotype control for NGM-120 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2387417-06-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990635. | |
| NG-nitro-L-arginine | NG-nitro-L-arginine (Nω-nitro-L-arginine) is a NO Synthase inhibitor, with K i s of 0.61 μM (nNOS), 4.28 μM (iNOS), 0.72 μM (eNOS) respectively. NG-nitro-L-arginine inhibits endothelium-derived relaxing factor ( EDRF ) formation and release. NG-nitro-L-arginine inhibits portal-systemic shunting in portal-hypertensive rats, and increases blood pressure [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nω-nitro-L-arginine; L-NOARG; L-NG-Nitroarginine. CAS No. 2149-70-4. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-12115. | |
| NH125 | NH125 is a potent and selective inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K/CaMKIII) , also can induce eEF2 phosphorylation, with an IC 50 of 60 nM for eEF-2K [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 278603-08-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100576. | |
| (NH2)2bpy | (NH2)2bpy (4,4'-Diamino-2,2'-bipyridine) is an organic compound commonly used as a catalyst and complexing reagent. It can form complexes with other metal ions or organic molecules, and can play a catalytic role in some organic synthesis reactions. In addition, this compound is also widely used in some chemical analysis and detection methods, such as in biological analysis and electrochemical analysis. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 4,4'-Diamino-2,2'-bipyridine. CAS No. 18511-69-8. Pack Sizes: 500 mg; 1 g. Product ID: HY-W004547. | |
| NH2-PEG3 | NH2-PEG3 (PROTAC Linker 35) is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker. NH2-PEG3 (PROTAC Linker 35) can be used in the synthesis of the PROTAC (β-NF-JQ1) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PROTAC Linker 35. CAS No. 6338-55-2. Pack Sizes: 1 g; 5 g. Product ID: HY-W007545. | |
| NH2-PEG8-acid | NH2-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. NH2-PEG8-acid also is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 756526-04-2. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W019798. | |
| NH-3 | NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC 50 of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment [1] [2] [3]. NH-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 447415-26-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141513. | |
| N-hexadecane-d34 | N-hexadecane-d 34 is the deuterium labeled N-hexadecane[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 15716-08-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W099580S1. | |
| N-Hexadecyltrimethylammonium hexafluorophosphate | N-hexadecyltrimethyl Ammonium hexafluorophosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 101079-29-2. Pack Sizes: 1 g; 5 g. Product ID: HY-W099577. | |
| N-Hexanoyl-DL-homoserine lactone | N-Hexanoyl-DL-homoserine lactone is a bacterial quorum sensing molecule produced in the rhizosphere. N-Hexanoyl-DL-homoserine lactone, a bacterial quorum sensing signal, induces transcriptional changes in Arabidopsis and may contribute to tuning plant growth to the microbial composition of the rhizosphere [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 106983-28-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W045071. | |
| N-Hexanoyl-L-homoserine lactone | N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). N-hexanoyl-L-homoserine lactone is also a mediator of bacterial quorum-sensing regulation. N-hexanoyl-L-homoserine lactone promotes lipid accumulation in algae. AHL is an intercellular communication signal molecule in the quorum sensing system of Gram-negative bacteria and a medium for mediating information exchange between eukaryotic plants and prokaryotic bacteria. AHL can affect bacteria activities, such as biofilm formation, pigment synthesis, and antibiotic synthesis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147852-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133685. | |
| NHSF | NHSF is a protein cross-linking agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2292112-27-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-159008. | |
| NHS-SS-biotin | NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 122266-55-1. Pack Sizes: 25 mg. Product ID: HY-140129. | |
| N-Hydroxyphthalimide | N-Hydroxyphthalimide is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 524-38-9. Pack Sizes: 50 g; 100 g. Product ID: HY-Y0396. | |
| N-Hydroxysuccinimide | N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is an activated ester commonly used in bioconjugation technologies such as protein labeling with fluorescent dyes and enzymes, chromatography supports, beads, nanoparticles, and microarrays Surface activation of glass slides, and chemically synthesized peptides [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: HOSu; 1-Hydroxy-2,5-pyrrolidinedione. CAS No. 6066-82-6. Pack Sizes: 5 g; 10 g. Product ID: HY-Y0623. | |
| N-Hydroxysulfosuccinimide sodium | N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 106627-54-7. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W002213. | |
| NI-42 | NI-42 (compound 13-d), a structurally orthogonal chemical probe for the BRPFs, is a biased, potent inhibitor of the BRD of the BRPFs ( IC 50 s of BRPF1/2/3=7.9/48/260 nM; K d s of BRPF1/2/3=40/210/940 nM) with excellent selectivity over nonclass IV BRD proteins [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1884640-99-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101121. | |
| NI-57 | NI-57 is an inhibitor of bromodomain and plant homeodomain finger-containing ( BRPF ) famlily of proteins, with IC 50 s of 3.1, 46 and 140 nM for BRPF1, BRPF2 (BRD1) and BRPF3, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1883548-89-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19537. | |
| Niacin | Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Nicotinic acid; Vitamin B3. CAS No. 59-67-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0143. | |
| Niacin (standard) | Niacin (Standard) is the analytical standard of Niacin. This product is intended for research and analytical applications. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Nicotinic acid (standard); Vitamin B3 (standard). CAS No. 59-67-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B0143R. | |
| Nialamide | Nialamide is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class that was used as an antidepressant. Uses: Scientific research. Group: Signaling pathways. CAS No. 51-12-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1199. | |
| Niaprazine | Niaprazine is a histamine H1-receptor antagonist. Niaprazine has antihistamine and antiserotonin activities and can be used for sleep disorder research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 27367-90-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105542. | |
| Nicarbazin | Nicarbazin is an effective anticoccidial agent for chickens [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 330-95-0. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-107814. | |
| Nicardipine | Nicardipine (YC-93 free base) is a calcium channel blocker with an IC 50 of 1 μM for blocking cardiac calcium channels. Nicardipine acts as an agent for chronic stable angina and for controlling blood pressure [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YC-93 free base. CAS No. 55985-32-5. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-12515. | |
| Nicardipine hydrochloride | Nicardipine hydrochloride (YC-93) is a calcium channel blocker with an IC 50 of 1 μM for blocking cardiac calcium channels. Nicardipine hydrochloride acts as an agent for chronic stable angina and for controlling blood pressure [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YC-93. CAS No. 54527-84-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-12515A. | |
| Nicardipine (hydrochloride) (Standard) | Nicardipine (hydrochloride) (Standard) is the analytical standard of Nicardipine (hydrochloride). This product is intended for research and analytical applications. Nicardipine hydrochloride (YC-93) is a calcium channel blocker with an IC 50 of 1 μM for blocking cardiac calcium channels. Nicardipine hydrochloride acts as an agent for chronic stable angina and for controlling blood pressure [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54527-84-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-12515AR. | |
| Nicergoline | Nicergoline, an ergoline derivative ester of bromonicotinic acid, is a potent, selective and orally active antagonist of α 1A -adrenoceptor. Nicergoline has vasodilator effects. Nicergoline also has ameliorative effects on cognitive function in mouse models of Alzheimer's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 27848-84-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0702. | |
| Niclosamide | Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research [1]. Niclosamide is a STAT3 inhibitor with an IC 50 of 0.25 μM in HeLa cells [4]. Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells [2] [3] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY2353. CAS No. 50-65-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B0497. | |
| Niclosamide olamine | Niclosamide (BAY2353) olamine is an orally active antihelminthic agent used in parasitic infection research [1]. Niclosamide olamin is a STAT3 inhibitor with an IC 50 of 0.25 μM in HeLa cells [4]. Niclosamide olamin has biological activities against cancer, and inhibits DNA replication in Vero E6 cells [2] [3] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY2353 olamine. CAS No. 1420-04-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0497C. | |
| Niclosamide (Standard) | Niclosamide (Standard) is the analytical standard of Niclosamide. This product is intended for research and analytical applications. Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research [1]. Niclosamide is a STAT3 inhibitor with an IC 50 of 0.25 μM in HeLa cells [4]. Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells [2] [3] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 50-65-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0497R. | |
| Nicodicosapent | Nicodicosapent is a fatty acid niacin conjugate that is also an inhibitor of the sterol regulatory element binding protein (SREBP) , a key regulator of cholesterol metabolism proteins such as PCSK9, HMG-CoA reductase, ATP citrate lyase, and NPC1L1. Uses: Scientific research. Group: Signaling pathways. CAS No. 1269181-69-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17640. | |
| Nicorandil | Nicorandil (SG-75) is a potent potassium channel activator and targets vascular nucleoside diphosphate-dependent K + channels and cardiac ATP-sensitive K + channels (K ATP ). Nicorandil is a nicotinamide ester with vasodilatory and cardioprotective effects and has the potential for angina and forischemic heart diseases [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SG-75. CAS No. 65141-46-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0341. | |
| Nicosulfuron | Nicosulfuron is efficient, harmless, antifungal and selective herbicide belonging to the sulfonylurea family. Nicosulfuron is also a photosynthetic system inhibitor and inhibits acetolactate synthase (ALS) enzyme activity. Nicosulfuron degradation by Plectosphaerella cucumerina AR1 is glucose concentration dependent in planktonic lifestyle. Nicosulfuron enhances the glycolysis pathway and tricarboxylic acid cycle to improve the adaptability of sweet maize. Nicosulfuron reduces the synthesis of branched-chain amino acids (BCAAs) , which is proming for maize cultivation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 111991-09-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B1876. | |
| Nicotelline | Nicotelline (Nicotellin) is a nicotine-related alkaloid, as well as a weak inhibitor of human cDNA-expressed cytochrome P-450 2A6 (CYP2A6). CYP2A6 mediates coumarin 7-hydroxylation, while Nicotelline fails to exhibit inhibition at 300 μM. Nicotelline can be used as a tracer and biomarker of particulate matter (PM) derived from tobacco smoke [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nicotellin. CAS No. 494-04-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135560. | |
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