MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Naloxegol oxalate | Naloxegol oxalate (NKTR-118 oxalate; AZ-13337019 oxalate) is a μ-opioid-receptor antagonist. Naloxegol oxalate inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NKTR-118 oxalate; AZ-13337019 oxalate. CAS No. 1354744-91-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-A0118A. |  |
| Naloxonazine dihydrochloride | Naloxonazine dihydrochloride is a specific μ-opioid receptor antagonist with an IC 50 of 5.4 nM. Naloxonazine dihydrochloride also shows anti-leishmanial activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 880759-65-9. Pack Sizes: 5 mg. Product ID: HY-101011. | |
| Naloxone | Naloxone is an antagonist of Opioid receptor. Naloxone alleviates opioid-overdose-induced respiratory depression. Naloxone may cause pulmonary edema and cardiac arrhythmias [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 465-65-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-17417A. | |
| Naloxone benzoylhydrazone | Naloxone benzoylhydrazone (NalBzoH) is a mixed agonist/antagonist. Naloxone benzoylhydrazone is a prototypic κ3-opioid receptor agonist, and a partial agonist at the cloned μ and δ opioid receptors , and an antagonist at opioid-like NOP receptors. Naloxone benzoylhydrazone has potently analgesia effect [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NalBzoH. CAS No. 119630-94-3. Pack Sizes: 1 mg. Product ID: HY-107743. | |
| Naloxone hydrochloride | Naloxone hydrochloride is an antagonist of Opioid receptor. Naloxone hydrochloride alleviates opioid-overdose-induced respiratory depression. Naloxone hydrochloride may cause pulmonary edema and cardiac arrhythmias [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 357-08-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-17417. | |
| Naloxone methiodide | Naloxone methiodide is a peripherally restricted, nonselective, and competitive opioid receptor antagonist. Naloxone methiodide does not penetrate the blood-brain barrier [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 93302-47-7. Pack Sizes: 1 mg. Product ID: HY-137279. | |
| Nα-Benzoyl-L-arginine 4-nitroanilide hydrochloride | Nα-Benzoyl-L-arginine 4-nitroanilide (hydrochloride) is aarginine derivatives. Uses: Scientific research. Group: Peptides. CAS No. 21653-40-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-137529. | |
| Naltrexone | Naltrexone is an antagonist of Opioid receptor. Naltrexone inhibits cell proliferation in vivo. Naltrexone reduces tumor growth by interfering with cell signalling and modifying the immune system [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 16590-41-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-76711. | |
| Naltriben mesylate | Naltriben mesylate is a potent δ2-opioid receptor antagonist and a TRPM7 activator. Naltriben mesylate shows K i values of 0.013 nM, 19 nM and 152 nM for δ, μ and κ receptors, respectively. Naltriben mesylate enhances glioblastoma cell migration and invasion. Naltriben mesylate can be used in research into neurological diseases and cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 122517-78-6. Pack Sizes: 5 mg. Product ID: HY-101302. | |
| NAMI-A | NAMI-A is a ruthenium-based agent characterized by selective activity against tumor metastasis, inhibiting adhesion and migration. Uses: Scientific research. Group: Signaling pathways. CAS No. 201653-76-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19376. | |
| Namilumab | Namilumab (AMG203) is a human IgG1 monoclonal antibody that binds with high affinity to the GM-CSF ligand , potently neutralizing GM-CSF. Namilumab can be used for the research of rheumatoid arthritis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG-203; Anti-Human CSF2 Recombinant Antibody. CAS No. 1206681-39-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99307. | |
| Namodenoson | Namodenoson (CF-102) is a selective A3 adenosine receptor ( A3AR ) agonist ( K i =0.33 nM). Namodenoson displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CF-102; 2-Cl-IB-MECA. CAS No. 163042-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12365. | |
| Nampt-IN-15 | Nampt-IN-15 (Example 3) is an Nampt inhibitor. Nampt-IN-15 shows cytotoxicity against BxPC-3, HepG2, L540cy and MOLM-13, with IC 50 s of 38.5 nM, 8 nM, 8.5 nM, 7 nM respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2222981-61-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-402237. | |
| Nampt-IN-5 | Nampt-IN-5 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor. Nampt-IN-5 also inhibits CYP3A4 activity and has cellular IC 50 s of 0.7 nM and 3.9 nM against A2780 and COR-L23, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2380013-17-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130606. | |
| NAN-190 hydrobromide | NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist. NAN-190 is a selective antagonist of 5-HT 1A [1] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 115338-32-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19818A. | |
| Nanatinostat | Nanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC 50 of 8 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CHR-3996. CAS No. 1256448-47-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13432. | |
| Napabucasin | Napabucasin (BBI608) is a STAT3 inhibitor which blocks stem cell activity in cancer cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BBI608. CAS No. 83280-65-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-13919. | |
| Naphazoline hydrochloride | Naphazoline (Naphthazoline) hydrochloride is a potent α-adrenergic receptor agonist. Naphazoline hydrochloride reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline hydrochloride reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline hydrochloride can be used for non-bacterial conjunctivitis research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Naphthazoline hydrochloride. CAS No. 550-99-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0446. | |
| Naphazoline nitrate | Naphazoline (Naphthazoline) nitrate is an α-adrenergic receptor agonist. Naphazoline nitrate reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline nitrate reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline nitrate can be used for non-bacterial conjunctivitis research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Naphthazoline nitrate. CAS No. 5144-52-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-111326A. | |
| Naphthalene-2,3-Dicarboxaldehyde | Naphthalene-2,3-Dicarboxaldehyde (2,3-Naphthalenedicarboxaldehyde), a phthaldehyde derivative, is a fungal ASADH inhibitor (K i : 45 ?M). Naphthalene-2,3-Dicarboxaldehyde inhibits the growth of C. albicans CAF2-1 with IC 50 of 58.2 ?M and MIC of 12 ?g/mL [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,3-Naphthalenedicarboxaldehyde; Naphthalene-2,3-dialdehyde. CAS No. 7149-49-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W016288. | |
| Naphthol AS-BI phosphate | Naphthol AS-BI phosphate is a substrate for acid and alkaline phosphatase and can be used in fluorescence assays. Naphthol AS-BI phosphate is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1919-91-1. Pack Sizes: 50 mg; 100 mg. Product ID: HY-131475. | |
| Naphthol AS-MX phosphate | Naphthol AS-MX phosphate (NASTRp) is a small molecule inhibitor of the CREB (cyclic adenosine phosphate reaction element binding protein)- CBP (CREB binding protein) transcription factor complex. Naphthol AS-MX phosphate shows antitumor activity against lung cancer cells, inhibiting tumor cell proliferation ( IC 50 =3.701 μmol/L), colony formation, and anchored independent growth in soft AGAR. Naphthol AS-MX phosphate can be used in the study of KRAS mutated lung cancer, especially for KRAS mutated lung cancer with poor chemotherapy resistance and prognosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NASTRp. CAS No. 1596-56-1. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-104067. | |
| Naphthol AS-TR phosphate disodium | Naphthol AS-TR Phosphate disodium is a water-soluble dye commonly used as an enzymatic substrate in various biochemical assays to detect alkaline phosphatase activity. Naphthol AS-TR Phosphate disodium has unique chemical properties that allow it to be hydrolyzed by alkaline phosphatase, forming a colored product that can be detected spectrophotometrically. This makes it a useful tool for monitoring enzyme activity in biological samples such as serum or urine. Uses: Scientific research. Group: Signaling pathways. CAS No. 4264-93-1. Pack Sizes: 100 mg. Product ID: HY-130767A. | |
| Naphthol green B | Naphthol green B is an iron-complex dye. Naphthol green B can be used in wool dyeing, silk dyeing and polyamide dyeing. Naphthol green B can be used to fabricate electrochemical sensor for the detection of H 2 O 2 [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 19381-50-1. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-W110905. | |
| Naphthoquine phosphate | Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia , including resistance of P. falciparum to Chloroquine [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 173531-58-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17036. | |
| Naporafenib | Naporafenib (LXH254) is a potent, selective, orally active, type II BRAF and CRAF inhibitor, with IC 50 values of 0.072 and 0.21 nM against CRAF and BRAF, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LXH254. CAS No. 1800398-38-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112089. | |
| NAPQI | NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 50700-49-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-W017464. | |
| Napropamide | Napropamide is an amide herbicide. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Napropamid. CAS No. 15299-99-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-B1972. | |
| Napropamide (Standard) | Napropamide (Standard) is the analytical standard of Napropamide. This product is intended for research and analytical applications. Napropamide is an amide herbicide. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Napropamid (Standard). CAS No. 15299-99-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1972R. | |
| Naproxen | Naproxen is a COX-1 and COX-2 inhibitor with IC 50 s of 8.72 and 5.15 μM, respectively in cell assay. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-Naproxen. CAS No. 22204-53-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-15030. | |
| (±)-Naproxen | (±)-Naproxen ((Rac)-Naproxen) is a racemate of Naproxen (HY-15030). Naproxen is a COX-1 and COX-2 inhibitor with IC 50 s of 8.72 and 5.15 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (Rac)-Naproxen; 2-(6-Methoxynaphthalen-2-yl)propanoic acid. CAS No. 23981-80-8. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-15029. | |
| (±)-Naproxen-d3 | (±)-Naproxen-d 3 is the deuterium labeled (±)-Naproxen. (±)-Naproxen is a non-steroidal anti-inflammatory drug (NSAID)[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (Rac)-Naproxen-d3. CAS No. 958293-79-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-15029S. | |
| Naproxen sodium | Naproxen sodium is a COX-1 and COX-2 inhibitor with IC 50 s of 8.72 and 5.15 μM, respectively in cell assay. Uses: Scientific research. Group: Signaling pathways. CAS No. 26159-34-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-15030A. | |
| Naptumomab | Naptumomab is a fusion protein of a tumor-targeting superantigen (TTS). Naptumomab stimulates the immune system to recognize and kill tumor cells and can be used in the study of refractory solid tumors such as renal cell carcinoma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1412892-09-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99035. | |
| N-Arachidonoylserotonin | N-Arachidonoylserotonin (Arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC 50 value of 1~12 μM. N-Arachidonoylserotonin acts also as an antagonist of transient receptor potential vanilloid-type 1 (TRPV1) channels (IC 50 =70~100 nM). N-Arachidonoylserotonin is analgesic in rodents [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Arachidonyl serotonin; AA-5-HT. CAS No. 187947-37-1. Pack Sizes: 5 mg (108.07 mM * 0.1 mL in methyl acetate); 10 mg (108.07 mM * 0.2 mL in methyl acetate); 25 mg (108.07 mM * 0.5 mL in methyl acetate); 50 mg (108.07 mM * 1 mL in methyl acetate). Product ID: HY-103337. | |
| N-Arachidonyldopamine | N-Arachidonyldopamine is a potent and selective endogenous CB1 receptor agonist with a K i of 250 nM [1]. N-Arachidonyldopamine is also a potent and selective TRPV1 agonist an with EC 50 of ~ 50 nM [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199875-69-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110018. | |
| N-Arachidonyl-GABA | N-Arachidonoyl-GABA is one member of a new class of lipoamino acids related to anandamide identified in bovine brain. N-Arachidonoyl-GABA displays analgesic activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 128201-89-8. Pack Sizes: 1 mg (64.17 mM * 40 μL in Ethanol); 5 mg (64.17 mM * 200 μL in Ethanol). Product ID: HY-103507. | |
| N-Arachidonylglycine | N-Arachidonylglycine (NA-Gly), a carboxylic analog of the endocannabinoid anandamide (AEA), is a GPR18 agonist ( EC 50 = 44.5 nM). Unlike AEA, N-Arachidonylglycine has no activity at either CB1 or CB2 receptors. N-Arachidonylglycine inhibits GLYT2 ( IC 50 = 5.1 μM). N-Arachidonylglycine also is an effective activator of endometrial cell migration [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: NA-Gly. CAS No. 179113-91-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103332. | |
| N-Arachidonylglycine-d8 | N-Arachidonylglycine-d8 is a deuterated labeled N-Arachidonylglycine [1]. N-Arachidonylglycine (NA-Gly), a carboxylic analog of the endocannabinoid anandamide (AEA), is a GPR18 agonist ( EC 50 = 44.5 nM). Unlike AEA, N-Arachidonylglycine has no activity at either CB1 or CB2 receptors. N-Arachidonylglycine inhibits GLYT2 ( IC 50 = 5.1 μM). N-Arachidonylglycine also is an effective activator of endometrial cell migration [2] [3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: NA-Gly-d8. CAS No. 1159908-44-7. Pack Sizes: 1 mg (2.71 mM * 1 mL in Ethanol). Product ID: HY-103332S. | |
| Narasin | Narasin is a cationic ionophore antibiotic and coccidiostat agent. Narasin inhibits NF-κB signaling and induces tumor cells apoptosis. Narasin has antimicrobial, antiviral anticancer activity. Narasin inhibits tumor metastasis and growth of ERα - positive breast cancer cells by inactivation of the TGF-β/SMAD3 and IL - 6/STAT3 signaling pathways [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 55134-13-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-121410. | |
| Naratriptan hydrochloride | Naratriptan hydrochloride is a selective 5-HT1 receptor subtype agonist and is a triptan drug that is used for the treatment of migraine headaches. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR-85548A hydrochloride. CAS No. 143388-64-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0197A. | |
| Naratuximab | Naratuximab (Anti-TSPAN26/CD37 Reference Antibody (naratuximab)) is a humanized monoclonal antibody that binds CD37 (TSPAN26). Naratuximab can be used to synthesize an ADC compound, Naratuximab emtansine [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-TSPAN26/CD37 Reference Antibody (naratuximab). CAS No. 1622327-39-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99374. | |
| Narazaciclib | Narazaciclib (ON123300), a strong and brain-penetrant [1] multi-kinase inhibitor, inhibits CDK4 ( IC 50 =3.9 nM), Ark5 ( IC 50 =5 nM), PDGFRβ ( IC 50 =26 nM), FGFR1 ( IC 50 =26 nM), RET ( IC 50 =9.2 nM), and FYN ( IC 50 =11 nM). Single agent Narazaciclib causes a dose-dependent suppression of phosphorylation of Akt as well as activation of Erk in brain tumors [2]. Narazaciclib inhibits CDK6 with an IC 50 of 9.82 nM [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ON123300. CAS No. 1357470-29-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12624. | |
| Narciclasine | Narciclasine is a plant growth modulator. Narciclasine modulates the Rho/Rho kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity as well as inducing actin stress fiber formation in a RhoA-dependent manner. Uses: Scientific research. Group: Natural products. Alternative Names: Lycoricidinol. CAS No. 29477-83-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-16563. | |
| Nardosinone | Nardosinone, isolated from Nardostachys chinensis , is the first enhancer of the neuritogenic action of dbcAMP and staurosporine. Nardosinone may become a useful pharmacological tool for studying the mechanism of action of not only nerve growth factor (NGF) but also both the neuritogenic substances [1]. Uses: Scientific research. Group: Natural products. CAS No. 23720-80-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-N0380. | |
| Naringenin | Naringenin is the predominant flavanone in Citrus reticulata Blanco; displays strong anti-inflammatory and antioxidant activities. Naringenin has anti- dengue virus (DENV) activity. Uses: Scientific research. Group: Natural products. CAS No. 480-41-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0100. | |
| (±)-Naringenin | (±)-Naringenin is an orally available anti-inflammatory agent that can regulate both acute and chronic inflammation responses, while also showing antioxidant, neuroprotective, liver-protective, and anti-cancer effects. (±)-Naringenin promotes vasodilation in endothelial cells by activating BK Ca channels in muscle cells. It also exerts protective effects against experimental colitis by inhibiting Toll-like receptor 4 / NF-κB signaling, making it useful in studies related to sepsis, fulminant hepatitis, fibrosis, and cancer research [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 67604-48-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W011641. | |
| Naringenin chalcone | Naringenin chalcone is an orally active intermediate in flavonol biosynthesis. Naringenin chalcone induces Apoptosis. Naringenin chalcone inhibits the production of MCP-1 and NO. Naringenin chalcone exhibits anticancer activity against glioblastoma. Naringenin chalcone has anti-inflammatory and anti-allergic properties [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 73692-50-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N3007. | |
| Naringin | Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin also inhibits proliferation and invasion and induces apoptosis in human osteosarcoma cells by inhibiting zinc finger E-box binding homeobox 1 ( Zeb1 ) [1] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Naringoside. CAS No. 10236-47-2. Pack Sizes: 10 mM * 1 mL; 200 mg; 10 g. Product ID: HY-N0153. | |
| Narirutin | Narirutin, one of the active constituents isolated from citrus fruits, has antioxidant and anti-inflammatory activities. Narirutin is a shikimate kinase inhibitor with anti-tubercular potency [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 14259-46-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0804. | |
| Narnatumab | Narnatumab (IMC-RON8) is a neutralizing human monoclonal antibody that blocks RON binding to its ligand, macrophage-stimulating protein (MSP) , with a K d of 32 pM. Narnatumab can be used for the research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IMC-RON8; LY3012219; Anti-MSPR/RON/CD136 Reference Antibody (narnatumab). CAS No. 1188275-92-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99375. | |
| Naronapride | Naronapride (ATI-7505) is a potent prokinetic 5-HT 4 receptor agonist. Naronapride can be used for gastrointestinal diseases research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ATI-7505. CAS No. 860174-12-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-121826. | |
| Narsoplimab | Narsoplimab (OMS 721) is a high-affinity fully human immunoglobulin gamma 4 (IgG4) monoclonal antibody that binds MASP-2 and blocks lectin pathway activation. Narsoplimab can be used in research of hematopoietic stem-cell transplantation and SARS-CoV-2 [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: OMS 721; Anti-MASP2 Reference Antibody (narsoplimab). CAS No. 2108782-45-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99376. | |
| Naspm | Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA ( CP-AMPA ) receptors antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-Naphthylacetyl spermine. CAS No. 122306-11-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12506. | |
| Nasunin | Nasunin, an antioxidant anthocyanin, possesses antiangiogenic activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Delphinidin-3-(p-coumaroylrutinoside)-5-glucoside. CAS No. 28463-30-1. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-N9396. | |
| NAT | NAT is an initial hit of NAMPT activator. NAMPT is the rate-limiting enzyme in the NAD salvage pathway, which makes it an attractive target for the research of many diseases associated with NAD exhaustion such as neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 831243-31-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144776. | |
| Natalizumab | Natalizumab is a recombinant, humanized IgG4 monoclonal antibody, binds to α4β1- integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 189261-10-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108831. | |
| Natalizumab (Solution) | Natalizumab (Solution) is a recombinant, humanized IgG4 monoclonal antibody, binds to α4β1- integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 189261-10-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108831A. | |
| Natamycin | Natamycin (Pimaricin) is a macrolide antibiotic agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Pimaricin. CAS No. 7681-93-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0133. | |
| Nateglinide | Nateglinide, a D-phenylalanine derivative, is an orally active and short-acting insulinotropic agent and a DPP IV inhibitor. Nateglinide inhibits ATP-sensitive K + channels in pancreatic β-cells. Nateglinide is used for the treatment of type 2 (non-insulin-dependent) diabetes mellitus [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A4166; Senaglinide. CAS No. 105816-04-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0422. | |
| Nattokinase, Natto fermentation | Nattokinase, Natto fermentation is a potent fibrinolytic enzyme. Nattokinase can break down blood clots by directly hydrolyzing fibrin and plasmin substrate. Nattokinase can be used for the research of cardiovascular diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133876-92-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-P2373. | |
| Nav1.7 inhibitor | Nav1.7 inhibitor (compound II), a sulfonamide, is a potent Nav1.7 inhibitor. Nav1.7 inhibitor has the potential for a wide range of disorders, particularly pain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1355631-24-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13985. | |
| NAV 26 | NAV 26 (compound 26) is a selective voltage-gated sodium channel Nav1.7 blocker with an IC 50 of 0.37 μM. NAV 26 can be used for pain research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1198160-14-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-118048. | |
| Navacaprant | Navacaprant (BTRX-335140) is a selective and orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC 50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. Navacaprant endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats. Navacaprant distributes well into the CNS and can be used for the research of neuropathy [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BTRX-335140; CYM-53093. CAS No. 2244614-14-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-124754. | |
| Navitoclax | Navitoclax (ABT-263) is a potent and orally active Bcl-2 family protein inhibitor that binds to multiple anti-apoptotic Bcl-2 family proteins, such as Bcl-x L , Bcl-2 and Bcl-w, with a K i of less than 1 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-263. CAS No. 923564-51-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10087. | |
| Navocaftor | Navocaftor (GLPG 3067), as a cystic fibrosis transmembrane regulator ( CFTR ), is a protein modulator (US 20200377491 Al, example 1) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GLPG 3067; ABBV-3067. CAS No. 2159103-66-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109152. | |
| Navtemadlin | Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC 50 of 0.6 nM. Navtemadlin binds to MDM2 with a K d of 0.045 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMG 232; KRT-232. CAS No. 1352066-68-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12296. | |
| Naxitamab | Naxitamab (Hu3F8) is a humanized monoclonal antibody targeting the disialoganglioside GD2. Naxitamab can be used in research of neuroblastoma, osteosarcoma and other GD2-positive cancers [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Naxitamab-gqgk; Humanized 3F8; Hu3F8. CAS No. 1879925-92-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99206. | |
| NBD-PE | NBD-PE is an effective lipid fluorescent probe (Excitation/Emission: 465/535 nm; Color: Green). NBD-PE offers a wide array of applications in membrane and cell biology [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 178119-00-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D1683. | |
| NBD Sphingosine | NBD Sphingosine (NBD-Sph), a fluorochrome, is a fluorescence-labeled sphingosine. NBD Sphingosine can be uesd for fluorescence assay for sphingosine kinases [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1449370-25-5. Pack Sizes: 50 μg (523.45 μM * 200 μL in Ethanol). Product ID: HY-130433. | |
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