MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Midecamycin | Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria. Uses: Scientific research. Group: Natural products. Alternative Names: SF-837; Antibiotic SF-837. CAS No. 35457-80-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1908. |  |
| Midodrine | Midodrine is an α1-receptor agonist, for the treatment of dysautonomia and orthostatic hypotension. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Midodrin. CAS No. 42794-76-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-12749. | |
| Midodrine hydrochloride | Midodrine hydrochloride ((±)-Midodrine hydrochloride) is an α1-receptor agonist, for the treatment of dysautonomia and orthostatic hypotension. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Midodrine hydrochloride. CAS No. 43218-56-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-12749A. | |
| Midostaurin | Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β/γ , Syk , Flk-1 , Akt , PKA , c-Kit , c-Fgr , c-Src , FLT3 , PDFRβ and VEGFR1/2 with IC 50 s ranging from 22-500 nM [1] [2]. Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin shows powerful anticancer effects [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PKC412; CGP 41251. CAS No. 120685-11-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10230. | |
| Mifamurtide | Mifamurtide (MTP-PE), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide has potential for use in rare disease and osteosarcoma research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MTP-PE; L-MTP-PE; CGP 19835. CAS No. 83461-56-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-13682. | |
| Mifamurtide sodium | Mifamurtide sodium (MTP-PE sodium), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide sodium is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide sodium has potential for use in rare disease and osteosarcoma research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MTP-PE sodium; L-MTP-PE sodium; CGP 19835 sodium. CAS No. 90825-43-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-13682B. | |
| Mifepristone | Mifepristone (RU486) is a progesterone receptor ( PR ) and glucocorticoid receptor ( GR ) antagonist with IC 50 s of 0.2 nM and 2.6 nM in in vitro assay [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RU486; RU 38486. CAS No. 84371-65-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-13683. | |
| Mifepristone (Standard) | Mifepristone (Standard) is the analytical standard of Mifepristone. This product is intended for research and analytical applications. Mifepristone (RU486) is a progesterone receptor ( PR ) and glucocorticoid receptor ( GR ) antagonist with IC 50 s of 0.2 nM and 2.6 nM in in vitro assay [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RU486 (Standard); RU 38486 (Standard). CAS No. 84371-65-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-13683R. | |
| Migalastat hydrochloride | Migalastat (GR181413A free base) hydrochloride is an orally active α-galactosidase A molecular chaperone, with an IC 50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR181413A. CAS No. 75172-81-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-14929A. | |
| Miglitol | Miglitol (BAY-m1099) is an orally active antidiabetic compound that inhibits the breakdown of glycoconjugates into glucose. Miglitol inhibits glycoside hydrolase enzymes called α-glucosidases. Miglitol inhibits oxidative stress-induced apoptosis and mitochondrial ROS over-production in endothelial cells by enhancement of AMP-activated protein kinase. Dietary supplementation with Miglitol from pre-onset stage in OLETF rats delays the onset and development of diabetes and preserves the insulin secretory function of pancreatic islets [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY1099; BAY-m1099. CAS No. 72432-03-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0481. | |
| Miglustat | Miglustat (N-Butyldeoxynojirimycin) is an orally active and reversible ceramide glucosyltransferase inhibitor. Miglustat can be used for the research of type I gaucher disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Butyldeoxynojirimycin; NB-DNJ; OGT 918. CAS No. 72599-27-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17020. | |
| Miglustat hydrochloride | Miglustat (N-Butyldeoxynojirimycin) hydrochloride is an orally active and reversible ceramide glucosyltransferase inhibitor. Miglustat hydrochloride can be used for the research of type I gaucher disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Butyldeoxynojirimycin hydrochloride; NB-DNJ hydrochloride; OGT 918 hydrochloride. CAS No. 210110-90-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17020A. | |
| Milademetan | Milademetan (DS-3032) is a specific and orally active MDM2 inhibitor for the research of acute myeloid leukemia (AML) or solid tumors. Milademetan (DS-3032) induces G1 cell cycle arrest , senescence and apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DS-3032. CAS No. 1398568-47-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101266. | |
| Milatuzumab | Milatuzumab (hLL1; MEDI-115) is a humanized anti- CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: hLL1; MEDI-115. CAS No. 899796-83-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99731. | |
| Milbemycin A3 | Milbemycin A3 is an insecticide with acaricidal and nematocidal activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 51596-10-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-130423. | |
| Milbemycin oxime | Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 129496-10-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0778. | |
| Milnacipran hydrochloride | Milnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI) used for fibromyalgia. Uses: Scientific research. Group: Signaling pathways. CAS No. 101152-94-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0168A. | |
| Milrinone | Milrinone is a PDE3 inhibitor, and also an inotrope and vasodilator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Win 47203. CAS No. 78415-72-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-14252. | |
| Miltefosine | Miltefosine is a broad spectrum antimicrobial, anti-leishmanial, phospholipid agent acting by inhibiting the PI3K/Akt activity [1] [2] [3] [4]. Miltefosine is an inhibitor of CTP-phosphocholine cytidyltransferase (CCT) [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HePC; Hexadecyl phosphocholine. CAS No. 58066-85-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-13685. | |
| Milvexian | Milvexian is an orally bioavailable, small-molecule, reversible, direct antagonists of factor Xia , with the K i of 0.11, 0.38, 0.64, 490, 350 nM for human, rabbit, dog, rat, mouse, respectively. Milvexian shows anti-thrombosis activity in vitro and in vivo, and can be used for thrombus study [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-986177; JNJ-70033093. CAS No. 1802425-99-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125856. | |
| MIM1 | MIM-1 is an inhibitor of myeloid cell factor 1 ( Mcl-1 ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Inhibitor of Mcl-1. CAS No. 509102-00-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16695. | |
| Mimosine | Mimosine, a tyrosine analog , can act as an antioxidant by its potent iron-binding activity [1]. Mimosine is a known chelator of Fe(III) [2]. Mimosine induces apoptosis through metal ion chelation, mitochondrial activation and ROS production in human leukemic cells [3]. Anti-cancer, antiinflammation. Uses: Scientific research. Group: Natural products. CAS No. 500-44-7. Pack Sizes: 25 mg; 50 mg. Product ID: HY-N0928. | |
| Minaprine dihydrochloride | Minaprine dihydrochloride is a reversible inhibitor of MAO-A; weakly inhibit acetylcholinesterase; an antidepressant for treatment of depression. Uses: Scientific research. Group: Signaling pathways. CAS No. 25953-17-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0884A. | |
| Minocycline hydrochloride | Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline hydrochloride shows anti-cancer , anti-inflammatory , and glutamate antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline hydrochloride inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13614-98-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17412. | |
| Minocycline (hydrochloride) (Standard) | Minocycline (hydrochloride) (Standard) is the analytical standard of Minocycline (hydrochloride). This product is intended for research and analytical applications. Minocycline hydrochloride is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline hydrochloride is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline hydrochloride shows anti-cancer , anti-inflammatory , and glutamate antagonist effects. Minocycline hydrochloride reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline hydrochloride inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13614-98-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17412R. | |
| Minodronic acid | Minodronic acid (YM-529) is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis , and inhibits metastasis of various types of cancer cells. Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YM-529. CAS No. 180064-38-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16322. | |
| Minodronic acid hydrate | Minodronic acid (YM-529) hydrate is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis , and inhibits metastasis of various types of cancer cells. Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YM-529 hydrate. CAS No. 155648-60-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16322A. | |
| Minoxidil | Minoxidil (U10858) is an ATP-sensitive potassium (K ATP ) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC 50 of 20 μM [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: U10858. CAS No. 38304-91-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0112. | |
| Minoxidil sulfate | Minoxidil sulfate, a potent and ATP-sensitive K + channel opener, is the sulfated metabolite of minoxidil. Minoxidil sulfate is considered as a vasodilator to promote hair growth in vivo [1] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 83701-22-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B1445. | |
| Minzasolmin | Minzasolmin is an alpha-synuclein oligomerization inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UCB0599; (R)-NPT200-11. CAS No. 1802518-92-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145580. | |
| m-Iodophenol | m-Iodophenol is a protaetia brevitarsis attractant [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 626-02-8. Pack Sizes: 5 g; 10 g; 25 g; 50 g; 100 g; 500 g. Product ID: HY-W007364. | |
| Mipasetamab | Mipasetamab is an IgG1κ antibody targeting to AXL , a tyrosine kinase receptor and an TAM Receptor. Mipasetamab involves in synthesis of ADCT-601 (Mipasetamab uzoptirine), an AXL-targeted antibody-drug conjugate (ADC). ADCT-601 has anti-tumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2361055-48-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99733. | |
| Mirabegron | Mirabegron is a selective β 3 -adrenoceptor agonist with EC 50 of 22.4 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YM178. CAS No. 223673-61-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14773. | |
| Miransertib | Miransertib (ARQ-092) is a potent, orally active, selective and allosteric Akt inhibitor with IC 50 s of 2.7 nM, 14 nM and 8.1 nM for Akt1 , Akt2 , Akt3 , respectively. Miransertib is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research [1]. Miransertib is effective against Leishmania [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARQ-092. CAS No. 1313881-70-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19719. | |
| Miransertib hydrochloride | Miransertib hydrochloride (ARQ-092 hydrochloride) is a potent, orally active, selective and allosteric Akt inhibitor with IC 50 s of 2.7 nM, 14 nM and 8.1 nM for Akt1 , Akt2 , Akt3 , respectively. Miransertib hydrochloride is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research [1]. Miransertib hydrochloride is effective against Leishmania [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARQ-092 hydrochloride. CAS No. 1313883-00-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19719A. | |
| Mirdametinib | Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC 50 of 0.33 nM. Mirdametinib exhibits a K i app of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD0325901; PD325901. CAS No. 391210-10-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10254. | |
| Miridesap | Miridesap is a ligand for serum amyloid P component ( SAP ) and intends to inhibit and dissociate SAP binding to amyloid fibrils and tangles. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPHPC; Ro63-8695; GSK2315698. CAS No. 224624-80-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101861. | |
| Mirikizumab | Mirikizumab (LY3074828) is a humanized IgG4 monoclonal antibody that targets the p19 subunit of interleukin 23 ( IL-23 ). Mirikizumab binds to human and monkey IL-23 with high affinity, with K d values of 21 pM and 55 pM, respectively. By inhibiting the binding of IL-23 to IL-23R , Mirikizumab modulates the immune response and holds potential for research in ulcerative colitis and Crohn's disease [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY-3074828. CAS No. 1884201-71-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99737. | |
| Mirin | Mirin is a potent Mre11-Rad50-Nbs1 (MRN) complex inhibitor. Mirin prevents MRN-dependent activation of ATM (IC 50 =12 μM) without affecting ATM protein kinase activity, and it inhibits Mre11-associated exonuclease activity. Mirin abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells. Mirin prevents ATM activation in response to DNA double-strand breaks (DSBs) and blocks homology-directed repair (HDR) in mammalian cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 299953-00-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117693. | |
| Miriplatin | Miriplatin (SM-11355) is a chemotherapy agent which belongs to the class of alkylating agents. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SM-11355. CAS No. 141977-79-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16325A. | |
| Mirodenafil | Mirodenafil (SK3530) is an orally active, potent, reversible, and selective phosphodiesterase 5 (PDE5) inhibitor. Mirodenafil is a glucocorticoid receptor (GR) modulator Mirodenafil activates the Wnt/β-catenin signaling pathway by downregulating Dkk1 expression. Mirodenafil can be used for the research of erectile dysfunction (ED), Alzheimers disease (AD) and systemic sclerosis (SSc) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SK3530. CAS No. 862189-95-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14930. | |
| Mirodenafil dihydrochloride | Mirodenafil (SK3530) dihydrochloride is an orally active, potent, reversible, and selective phosphodiesterase 5 (PDE5) inhibitor. Mirodenafil dihydrochloride is a glucocorticoid receptor (GR) modulator Mirodenafil dihydrochloride activates the Wnt/β-catenin signaling pathway by downregulating Dkk1 expression. Mirodenafil dihydrochloride can be used for the research of erectile dysfunction (ED), Alzheimers disease (AD) and systemic sclerosis (SSc) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SK-3530 dihydrochloride. CAS No. 862189-96-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14930A. | |
| Mirogabalin | Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DS5565. CAS No. 1138245-13-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12650. | |
| Mirogabalin besylate | Mirogabalin besylate is a selective and orally available ligand for the α2δ subunit of voltage-gated calcium channels , with K d s of 13.5 nM, 22.7 nM, 27 nM, and 47.6 nM for human α2δ-1, human α2δ-2, rat α2δ-1, and rat α2δ-2, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DS 5565 besylate. CAS No. 1138245-21-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108006. | |
| Mirtazapine | Mirtazapine (Org3770) is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. Mirtazapine is also a 5-HT 2 , 5-HT 3 , histamine H1 receptor and α2-adrenoceptor antagonist with pK i values of 8.05, 8.1, 9.3 and 6.95, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Org3770; 6-Azamianserin. CAS No. 85650-52-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0352. | |
| Mirtazapine (Standard) | Mirtazapine (Standard) is the analytical standard of Mirtazapine. This product is intended for research and analytical applications. Mirtazapine (Org3770) is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. Mirtazapine is also a 5-HT 2 , 5-HT 3 , histamine H1 receptor and α2-adrenoceptor antagonist with pK i values of 8.05, 8.1, 9.3 and 6.95, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Org3770 (Standard); 6-Azamianserin (Standard). CAS No. 85650-52-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0352R. | |
| Mirvetuximab | Mirvetuximab (M9346A) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: M9346A. CAS No. 1453084-36-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99225. | |
| Mirvetuximab soravtansine (solution) | Mirvetuximab soravtansine (IMGN853) solution is an anti-folate receptor α ( FRα ) antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A. Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IMGN853 (solution). CAS No. 1453084-37-1. Pack Sizes: 1 mg (10.246 mg/mL * 97.6 μL in 10mM Histidine pH=5.5); 5 mg (10.246 mg/mL * 488 μL in 10mM Histidine pH=5.5). Product ID: HY-132258A. | |
| Misonidazole | Misonidazole (Ro 7-0582; SR 1354) is a hypoxic tumor cell radiosensitizer [1]. Misonidazole also has antimicrobial effects [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 7-0582; SR 1354. CAS No. 13551-87-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-105061. | |
| Mitapivat | Mitapivat (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase) -deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-348. CAS No. 1260075-17-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12689. | |
| Mitazalimab | Mitazalimab (ADC-1013; JNJ-64457107) is FcγR-dependent CD40 agonist with tumor-directed activity. Mitazalimab activates antigen-presenting cells, e.g. dendritic cells (DC), to initiate tumor-reactive T cells. Therefore, Mitazalimab induces tumor-specific T cells to infiltrate and kill tumors. Mitazalimab remodels the tumor-infiltrating myeloid microenvironment [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ADC-1013; JNJ-64457107. CAS No. 2055640-86-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99742. | |
| Mitiglinide calcium | Mitiglinide Calcium (KAD-1229 anhydrous), an insulinotropic agent, is an ATP-sensitive K + (K ATP ) channel antagonist. Mitiglinide Calcium is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell K ATP channel). Mitiglinide Calcium can be used for the research of type 2 diabetes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KAD-1229 anhydrous; S21403 anhydrous. CAS No. 145525-41-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-17398. | |
| Mitiglinide calcium hydrate | Mitiglinide calcium hydrate (KAD-1229), an insulinotropic agent, is an ATP-sensitive K + (K ATP ) channel antagonist. Mitiglinide calcium hydrate is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell K ATP channel). Mitiglinide Calcium hydrate can be used for the research of type 2 diabetes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KAD-1229; S-21403. CAS No. 207844-01-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0682A. | |
| Mitiperstat | Mitiperstat (AZD4831) is an effective oral inhibitor of myeloperoxidase (MPO). Mitiperstat can reduce inflammation and improve microvascular function, and it can be used in studies related to heart failure, preserved or mildly reduced ejection fraction, non-alcoholic fatty liver disease, and chronic obstructive pulmonary disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD4831. CAS No. 1933460-19-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145581. | |
| Mitochonic acid 5 | Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage. Mitochonic acid 5 modulates mitochondrial ATP synthesis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MA-5. CAS No. 1354707-41-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111536. | |
| Mitoguazone | Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-GAG. CAS No. 459-86-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-106634. | |
| Mitomycin A | Mitomycin A is a bacterial metabolite. Mitomycin A reduces migration inhibition factor ( MIF ) production and can be used for the research of cancer [1]. Uses: Scientific research. Group: Natural products. CAS No. 4055-39-4. Pack Sizes: 500 μg. Product ID: HY-130332. | |
| Mitoquinol | Mitoquinol is a mitochondrial-targeted coenzyme Q analog. Mitoquinol is an antioxidant that inhibits lipid peroxidation. Mitoquinol can be used in vascular disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 845959-55-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124410. | |
| Mitoquinone mesylate | Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant in order to protect against oxidative damage [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MitoQ mesylate; MitoQ10 mesylate. CAS No. 845959-50-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100116A. | |
| Mitotane | Mitotane (2,4-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,4-DDD; o,p'-DDD. CAS No. 53-19-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-13690. | |
| MitoTEMPO hydrate | Mito-TEMPO is a mitochondria-targeted antioxidant that possesses superoxide and alkyl radical scavenging properties. Mito-TEMPO helps protect against oxidative damage to the mitochondria [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1569257-94-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125944. | |
| MitoTEMPOL | MitoTEMPOL is a a mitochondria-targeted nitroxide that reduces mitochondrial O2 - to H2O2 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1101113-39-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-115386. | |
| Mitoxantrone | Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C ( PKC ) activity with an IC 50 of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity [1] [2] [3] [4]. Mitoxantrone also has anti- orthopoxvirus activity with EC 50 s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Mitozantrone; NSC 301739. CAS No. 65271-80-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13502. | |
| Mitoxantrone dihydrochloride | Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C ( PKC ) activity with an IC 50 of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity [1] [2] [3] [4]. Mitoxantrone dihydrochloride also has anti- orthopoxvirus activity with EC 50 s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Mitozantrone dihydrochloride; NSC 301739 dihydrochloride. CAS No. 70476-82-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13502A. | |
| Mitraphylline | Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils [1]. Uses: Scientific research. Group: Natural products. CAS No. 509-80-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6946. | |
| Mivacurium dichloride | Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 106861-44-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1700A. | |
| Mivebresib | Mivebresib (ABBV-075) is a potent and orally active bromodomain and extraterminal domain (BET) bromodomain inhibitor. Mivebresib binds to BRD4 with a K i of 1.5 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABBV-075. CAS No. 1445993-26-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100015. | |
| Mizagliflozin | Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a K i of 27 nM for human SGLT1. Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic agent that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DSP-3235 free base; KGA-3235 free base; GSK-1614235 free base. CAS No. 666843-10-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17638. | |
| Mizolastine | Mizolastine is an orally active, high affinity and specific peripheral histamine H1 receptor antagonist (second generation antihistamine). Mizolastine effectively inhibits mRNA expression of VEGF165 , VEGF120 , TNF-α and KC. Mizolastine can be used in studies of allergic rhinitis and chronic idiopathic urticarial [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 108612-45-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0164. | |
| Mizoribine | Mizoribine (NSC 289637), an imidazole nucleoside, inhibits HCV RNA replication with IC 50 of approximately 100 μM for anti-HCV activity. Immunosuppressant [1]. Mizoribine, an IMPDH inhibitor, inhibits replication of SARS-CoV with IC 50 s of 3.5 μg/mL and 16 μg/mL for SARS-CoV Frankfurt-1 and SARS-CoV HKU39849, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 289637; HE 69. CAS No. 50924-49-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17470. | |
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