MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Ipivivint | Ipivivint (Compound 38) is an orally active and potent CDC-like kinase (CLK) inhibitor with EC50 of 1 nM and 7 nM for CLK2 (human) and CLK3 (human), respectively. Ipivivint also inhibits the Wnt pathway (EC50=13 nM) and tyrosine phosphorylation-regulated kinase 1A (human) (EC50=5 nM)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1481617-15-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137443. |  |
| IPR-803 | IPR-803 is a potent inhibitor of the uPAR·uPA protein-protein interaction (PPI). IPR-803 binds directly to uPAR with sub-micromolar affinity. IPR-803 displays anti-tumor activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 892243-35-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111192. | |
| Ipragliflozin | Ipragliflozin (ASP1941) is an orally active and selective SGLT2 inhibitor with IC 50 s of 7.38 and 1876 nM, 6.73 and 1166 nM, 5.64 and 1380 nM for human SGLT2 and SGLT1, rat SGLT2 and SGLT1, mouse SGLT2 and SGLT1, respectively. Antidiabetic agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASP1941. CAS No. 761423-87-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-14894. | |
| Ipratropium bromide | Ipratropium bromide (Sch 1000) is a muscarinic receptor antagonist, with IC 50 s of 2.9 nM, 2 nM, and 1.7 nM for M1, M2, and M3 receptors, respectively. Ipratropium bromide relaxes smooth muscle, can be used in the research for COPD (chronic obstructive pulmonary disease) and asthma [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sch 1000. CAS No. 22254-24-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0241. | |
| Ipratropium bromide hydrate | Ipratropium bromide (Sch 1000) hydrate is a muscarinic receptor antagonist, with IC 50 s of 2.9 nM, 2 nM, and 1.7 nM for M1, M2, and M3 receptors, respectively. Ipratropium bromide hydrate relaxes smooth muscle, can be used in the research for COPD (chronic obstructive pulmonary disease) and asthma [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sch 1000 bromide hydrate. CAS No. 66985-17-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B1332. | |
| Ipriflavone | Ipriflavone is a synthetic isoflavone derivative used to suppress bone resorption. Uses: Scientific research. Group: Signaling pathways. CAS No. 35212-22-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N0094. | |
| Iprindole | Iprindole, a tricyclic indole antidepressant, is a weak inhibitor of the uptake of noradrenaline and 5-HT [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5560-72-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12392. | |
| Iprobenfos | Iprobenfos is an organophosphorus fungicide and is widely used to control the rice blast fungus. Iprobenfos is also a choline biosynthesis inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 26087-47-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1863. | |
| Iprodione | Iprodione is an orally active diformimide fungicide. Iprodione can specifically cause oxidative damage by producing free radicals (ROS). Iprodione is also an antiandrogen agent that delays adolescent development in rats and reduces sexual behavior and reproductive ability in rats [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 36734-19-7. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-B1978. | |
| Iproniazid | Iproniazid is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid has antidepressive activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54-92-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0886A. | |
| Iproniazid phosphate | Iproniazid phosphate is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid phosphate has antidepressive activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 305-33-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0886. | |
| Ipronidazole | Ipronidazole (RO-71554) is an orally active antihistomonal agent, which prevents and ameliorates enterohepatitis in turkeys. Ipronidazole can promotes turkey growth when supplied in feed or drinking water [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO-71554. CAS No. 14885-29-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-151217. | |
| Ipsapirone | Ipsapirone (TVX Q 7821) is an anxiolytic compound and a 5-HT 1A receptor partial agonist. Ipsapirone (TVX Q 7821) also exhibits 5-HT 1A receptor antagonistic effect, and only at high doses it can also produce an inhibitory effect on 5-HT 2 and the α 1 -adrenergic function [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TVX Q 7821 free base. CAS No. 95847-70-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19686. | |
| IPSU | IPSU is a selective, orally available and brain penetrant OX2R antagonist with a pK i of 7.85. Uses: Scientific research. Group: Signaling pathways. CAS No. 1373765-19-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-13796. | |
| Iptacopan | Iptacopan (LNP023) is a first-in-class, orally bioavailable, highly potent and highly selective factor B inhibitor with an IC 50 value of 10 nM. Iptacopan shows direct, reversible, and high-affinity binding to human factor B with a K D of 7.9 nM. Iptacopan targets the underlying cause of complement 3 glomerulopathy (C3G) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LNP023. CAS No. 1644670-37-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127105. | |
| Iptacopan hydrochloride | LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor. LNP023 shows direct, reversible, and high-affinity binding to human factor B with a K D of 7.9 nM. LNP023 inhibits factor B with an IC 50 value of 10 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LNP023 hydrochloride. CAS No. 1646321-63-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127105A. | |
| Iptakalim hydrochloride | Iptakalim hydrochloride, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (K ATP ) opener, as well as an α 4 β 2 -containing nicotinic acetylcholine receptor (nAChR) antagonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 642407-63-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108069. | |
| IPTG | IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Isopropyl β-D-thiogalactoside. CAS No. 367-93-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-15921. | |
| IQ 1 | IQ 1 is a Wnt/β-catenin/CBP signalling sustainer. IQ 1 maintains long-term expansion of Wnt/β-catenin -driven mouse embryonic stem cells (ESCs) and prevents spontaneous differentiation by enhancing β-catenin/CBP -mediated transcription and preventing conversion to β-catenin/p300 -mediated transcription. IQ-1 regulates Wnt signalling by interacting with PR72/130. IQ 1 can be used in study of ESCs expansion [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 331001-62-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10593. | |
| IQ-3 | IQ-3 is a specific inhibitor of the c-Jun N-terminal kinase (JNK) family, with preference for JNK3. IQ-3 exhibits K d values of 0.24 μM, 0.29 μM and 0.066 μM for JNK1, JNK2 and JNK3, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312538-03-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107600. | |
| IR-780 | IR780 is a prototypic NIR heptamethine cyanine agent, with a high molar extinction coefficient. The maximum excitation wavelength of IR780 was 777-780 nm, and the maximum emission wavelength was 798-823 nm. IR780 can be used in cancer PTT/PDT and imaging [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 207399-07-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1063. | |
| IR-783 | IR-783 (ADS 780WS) is a near-infrared (NIR) heptamethine cyanine fluorescent probe. IR-783 significantly inhibits tumour growth and induces apoptosis in MDA-MB-231 xenograft model. IR-783 can be used to study breast cancer [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: ADS 780WS. CAS No. 115970-66-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-139109. | |
| IR-797 chloride | IR-797 chloride is a near-infrared (NIR) dye. IR 797 has absorption maxima near 700 nm. IR-797 shows some aggregation-induced-emission (AIE) properties. IR-797 shows shows cytotoxic [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 110992-55-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1504. | |
| IR 813 tosylate | IR 813 tosylate is a near-infrared (NIR) fluorescent dye (λ ex =815 nm, λ em =840 nm) and can be used for visualizing regional lymph nodes in mice [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 134127-48-3. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-W248594. | |
| IR-820 | IR-820 (New Indocyanine Green) is an infrared blood pool contrast agent. IR-820 also is normally used as a laser and near-infrared dye to detect and quantify diseased tissue in live animals[1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: New Indocyanine Green. CAS No. 172616-80-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-136886. | |
| IRAK-1-4 Inhibitor I | IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor-associated kinase 1/4 (IRAK 1/4) with IC50s of 0.2 ?M and 0.3 ?M, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IRAK-1/4 Inhibitor I. CAS No. 509093-47-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13329. | |
| IRAK inhibitor 4 | IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4( IRAK4 ) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1012104-68-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-13278. | |
| Irbesartan | Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR-47436; BMS-186295. CAS No. 138402-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0202. | |
| [Ir(Cp-)Cl2]2 | [Ir(Cp-)Cl2]2 is used as a precursor for the asymmetric transfer hydrogenation catalyst of ketones. It is a catalyst for greener amine synthesis[1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Pentamethylcyclopentadienyliridium(III) chloride,dimer. CAS No. 12354-84-6. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W018845. | |
| Irdabisant | Irdabisant (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant histamine H3 receptor (H3R) inverse agonist/inverse agonist with K i values of 7.2 nM and 2.0 nM for rat H3R and human H3R, respectively. Irdabisant has relatively low inhibitory activity against hERG current with an IC 50 of 13.8 μM. Irdabisant has cognition-enhancing and wake-promoting activities in the rat social recognition model. Irdabisant can be used to research schizophrenia or cognitive impairment [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CEP-26401. CAS No. 1005402-19-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-109968. | |
| IRF1-IN-1 | IRF1-IN-1 (Compound I-2) is an IRF1 inhibitor. IRF1-IN-1 decreases the recruitment of IRF1 to the promoter of CASP1. IRF1-IN-1 inhibits cell death signaling pathway (i.e., cleavage of Caspase 1 , GSDMD , IL-1 and PARP1 ). IRF1-IN-1 has a protective effect on ionizing radiation-induced inflammatory skin injury [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 701225-07-2. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-171006. | |
| IRF5-IN-1 | IRF5-IN-1 (Compound C5) is a conformationally locked inhibitor for SLC15A4. IRF5-IN-1 blocks the downstream IRF5 activation, inhibits the TLR7/8 signaling pathway. IRF5-IN-1 exhibits anti-inflammatory responses[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 689270-18-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149652. | |
| IRG1-IN-1 | IRG1-IN-1 is an itaconic acid derivative. IRG1-IN-1 can inhibit immune-responsive gene 1 (IRG1) activity. IRG1-IN-1 can be used for the research of cancer, inflammation and autoimmune diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2407652-42-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148335. | |
| iRGD peptide | iRGD peptide is a 9-amino acid cyclic peptide, triggers tissue penetration of agents by first binding to ?v-integrins, then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. Uses: Scientific research. Group: Peptides. Alternative Names: c(CRGDKGPDC). CAS No. 1392278-76-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0122. | |
| Iridin | Iridin is an isoflavone isolated from Iris milesii [1]. Uses: Scientific research. Group: Natural products. CAS No. 491-74-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N3011. | |
| Iridium(III) chloride hydrate | Iridium(III) chloride (hydrate) (Iridium trichloride (hydrate)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Iridium trichloride hydrate. CAS No. 14996-61-3. Pack Sizes: 100 mg; 250 mg. Product ID: HY-W021022. | |
| Irigenin | Irigenin is a is a lead compound, and mediates its anti-metastatic effect by specifically and selectively blocking α9β1 and α4β1 integrins binding sites on C-C loop of Extra Domain A (EDA). Irigenin shows anti-cancer properties. It sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 548-76-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-N2587. | |
| Irinotecan | Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Irinotecan; CPT-11; VAL-413(free base). CAS No. 97682-44-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16562. | |
| Irinotecan-d10 | Irinotecan-d 10 is a deuterium labeled Irinotecan ((+)-Irinotecan). Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (+)-Irinotecan-d10; CPT-11-d10; VAL-413-d10. CAS No. 718613-28-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-16562S. | |
| Irinotecan-d10 hydrochloride | Irinotecan-d 10 (hydrochloride) is the deuterium labeled Irinotecan. Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 718612-62-5. Pack Sizes: 1 mg. Product ID: HY-16562S1. | |
| Irinotecan hydrochloride | Irinotecan hydrochloride ((+)-Irinotecan hydrochloride) is a topoisomerase I inhibitor mainly used to treat colon cancer and rectal cancer [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Irinotecan hydrochloride; CPT-11 hydrochloride; VAL-413. CAS No. 100286-90-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16562A. | |
| Irinotecan hydrochloride trihydrate | Irinotecan hydrochloride trihydrate ((+)-Irinotecan hydrochloride trihydrate) is a topoisomerase I inhibitor with antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Irinotecan hydrochloride trihydrate; CPT-11 hydrochloride trihydrate. CAS No. 136572-09-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16568. | |
| Irisflorentin | Irisflorentin, a naturally occurring isoflavone, is an abundant active constituent in Belamcanda chinensis. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Anti-inflammatory activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 41743-73-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0268. | |
| IRL-1620 TFA | IRL-1620 (TFA) is a potent and selective endothelin receptor type B (ETB) agonist with a Ki of 16 pM[1]. Uses: Scientific research. Group: Peptides. Pack Sizes: 500 ?g; 1 mg; 5 mg. Product ID: HY-16465A. | |
| Irloxacin | Irloxacin (Pirfloxacin) is a quinolone antibacterial agent. Irloxacin shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria. Orally active [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pirfloxacin. CAS No. 91524-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105033. | |
| (-)-Irofulven | (-)-Irofulven (MGI 114), an Illudin S analog, is a DNA alkylating agent. (-)-Irofulven inhibits the replication of DNA, induces tumor cells apoptosis , and has potent antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGI 114; 6-Hydroxymethylacylfulvene; NSC 683863. CAS No. 158440-71-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-14429. | |
| Iron dextran | Iron dextran (Fe dextran) can be used in the study of iron-deficiency anemia in animals [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fe dextran. CAS No. 9004-66-4. Pack Sizes: 5 mL; 25 mL. Product ID: HY-107928. | |
| Iron(II) fumarate | Iron (II) fumarate is an orally effective active dietary supplement. Iron (II) fumarate can alleviate metabolic damage and damage to silkworms caused by cypermethrin (HY-123178). Iron (II) fumarate can be used for research on iron deficiency anemia [1] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ferrous fumarate. CAS No. 141-01-5. Pack Sizes: 500 mg; 1 g. Product ID: HY-B1651. | |
| Iron(II) gluconate | Iron(II) gluconate is a kind of biochemical reagent. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 699014-53-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W698286. | |
| Iron(II) sulfate heptahydrate, 99% | Iron(II) sulfate heptahydrate, 99% is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ferrous sulfate heptahydrate, 99%. CAS No. 7782-63-0. Pack Sizes: 25 g. Product ID: HY-Y1103. | |
| Iron(II) sulfate heptahydrate, for cell culture, 99% | Iron(II) sulfate heptahydrate, for cell culture, 99% is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ferrous sulfate heptahydrate, for cell culture, 99%. CAS No. 7782-63-0. Pack Sizes: 25 g. Product ID: HY-Y1103A. | |
| Iron sucrose | Iron sucrose (Iron saccharate) is a intravenous iron preparation and a pro-oxidant agent. Iron sucrose has the potential for iron deficiency anemia treatment [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Iron saccharate. CAS No. 8047-67-4. Pack Sizes: 25 mg; 100 mg. Product ID: HY-B2068. | |
| Irosustat | Irosustat is a potent steroid sulfatase inhibitor, with an IC 50 of 8 nM, and exhibits anti-breast cancer activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STX64; BN83495; 667-Coumate. CAS No. 288628-05-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14586. | |
| Irsenontrine | Irsenontrine (E2027) is an orally active and selective phosphodiesterase 9 ( PDE9 ) inhibitor. Irsenontrine can be used for the research of neurological diseases [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E2027. CAS No. 1429509-82-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132821. | |
| Irsogladine | Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dicloguamine. CAS No. 57381-26-7. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B0327. | |
| Iruplinalkib | Iruplinalkib (WX-0593) is an orally active and selective ALK/ROS1 inhibitor. Iruplinalkib can effectively inhibit tyrosine autophosphorylation of ALK and mutant ALK , EGFR , with the IC 50 between 5.38 and 16.74 nM. Iruplinalkib is also a suppressive agent of the transporter MATE1 , MATE2K , P-gp and BCRP. Iruplinalkib can be used in the study of non-small cell lung cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WX-0593. CAS No. 1854943-32-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145574. | |
| ISA-2011B | ISA-2011B is a PIP5K1? inhibitor with promising anticancer effects. Uses: Scientific research. Group: Signaling pathways. CAS No. 1395347-24-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16937. | |
| Isatin | Isatin (Indoline-2,3-dione) is a potent inhibitor of monoamine oxidase (MAO) with an IC 50 of 3 μM. Also binds to central benzodiazepine receptors (IC 50 against clonazepam, 123 μM) [1]. Also acts as an antagonist of both atrial natriuretic peptide stimulated and nitric oxide-stimulated guanylate cyclase activity [2]. Shows effect on the serotonergic system [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Indoline-2,3-dione. CAS No. 91-56-5. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Y0265. | |
| Isatoic anhydride | Isatoic anhydride is a molecule with a structure similar to trans-bis-isatoic anhydride (TBIA), but has only one reactive group. Isatoic anhydride forms monoadducts [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 118-48-9. Pack Sizes: 10 mM * 1 mL; 50 g; 100 g; 250 g; 500 g. Product ID: HY-76222. | |
| Isatuximab | Isatuximab is a monoclonal antibody targeting the transmembrane receptor and ectoenzyme CD38 , a protein highly expressed on hematological malignant cells, including those in multiple myeloma (MM). Isatuximab has antitumor activity via multiple biological mechanisms, including antibody-dependent cellular-mediated cytotoxicity, complement-dependent cytotoxicity, antibody-dependent cellular phagocytosis, and direct induction of apoptosis without crosslinking. Isatuximab also directly inhibits CD38 ectoenzyme activity, which is implicated in many cellular functions [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1461640-62-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9976. | |
| Isatuximab (anti-CD38) | Isatuximab (anti-CD38) is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38.Isatuximab induces tumor cell killing via fragment crystallizable (Fc)-dependent or Fc-independent mechanisms, including antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and complement-dependent cytotoxicity (CDC) [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1461640-62-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9976A. | |
| Isavuconazole | Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAL-4815; RO-0094815. CAS No. 241479-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14273. | |
| Isavuconazole-d4 | Isavuconazole-d 4 is a deuterium labeled Isavuconazole (BAL-4815). Isavuconazole is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: BAL-4815-d4; RO-0094815-d4. CAS No. 1346598-58-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-14273S. | |
| Isavuconazonium sulfate | Isavuconazonium sulfate (BAL8557-002) is an orally active broad-spectrum antifungal molecule. Isavuconazonium sulfate is a precursor of the triazole antifungal active molecule Isavuconazole. Isavuconazonium sulfate can be used in the study of invasive aspergillosis, mucormycosis, blastomycosis, and Acanthamoeba keratitis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAL8557-002. CAS No. 946075-13-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100373. | |
| Iscalimab | Iscalimab (CFZ-533) is a non-depleting IGg1 monoclonal antibody targeting CD40 ( K D : 0.3 nM). Iscalimab can be used for research of Graves' hyperthyroidism and autoimmune diseases [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CFZ-533; OM11-62MF. CAS No. 2031153-61-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99670. | |
| Iseganan | Iseganan is an anti-microbial peptide that is active against both Gram-positive and Gram-negative bacteria and fungi. Iseganan kills a broad-spectrum of bacteria and fungi by attaching to and destroying the integrity of the lipid cell membranes. Iseganan can be used for oral mucositis research [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: IB-367. CAS No. 257277-05-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3512. | |
| Isepamicin sulfate | Isepamicin sulfate (Sch 21420 sulfate) is a broad spectrum aminoglycoside antibiotic. Isepamicin sulfate exhibits considerable antimicrobial activity against Gram-negative non-fermenters in a region with high antimicrobial resistance [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sch 21420 sulfate. CAS No. 67814-76-0. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100589. | |
| Isethionic acid (80% in water) | Isethionic acid (2-Hydroxyethanesulfonic acid) (80% in water) is an organosulfur compound. Isethionic acid (80% in water) is widely distributed in animal species and in a few red algal species. Isethionic acid (80% in water) can be used as an anionic detergent and has anti-settlement activity against Balanus amphitrite [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Hydroxyethanesulfonic acid. CAS No. 107-36-8. Pack Sizes: 500 mg (12.67 M * 312.88 μL in Water). Product ID: HY-Y0095. | |
| Isethionic acid sodium salt | Isethionic acid sodium salt is an endogenous metabolite. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium 1-hydroxy-2-ethanesulfonate; Sodium 2-hydroxy-1-ethanesulfonate; Sodium 2-hydroxyethanesulfonate. CAS No. 1562-00-1. Pack Sizes: 500 mg; 1 g. Product ID: HY-Y1173. | |
| Islatravir | Islatravir (MK-8591) is a potent anti- HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC 50 s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. Islatravir is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-8591. CAS No. 865363-93-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104012. | |
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