MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| HP-β-CD | HP-β-CD ((2-Hydroxypropyl)-β-cyclodextrin) is a widely used drug delivery vehicle to improve the stability and bioavailability. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (2-Hydroxypropyl)-β-cyclodextrin. CAS No. 128446-35-5. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-101103. |  |
| H-Phe(2-Me)-OH | H-Phe(2-Me)-OH is a phenylalanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 80126-53-0. Pack Sizes: 10 g; 25 g. Product ID: HY-W016555. | |
| HPi1 | HPi1 is a potent, selective and orally active antimicrobial against Helicobacter pylori with an IC 50 of 0.24 μM and an MIC of 0.08-0.16 μg/mL. HPi1 is inactive against other bacteria, including the gut commensals Lactobacillus casei , Lactobacillus reuteri , and Bifidobacterium longum [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13080-21-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120536. | |
| HPMC | HPMC (Hypromellose) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Hypromellose; (Hydroxypropyl)methyl cellulose; Celacol HPM 5000. CAS No. 9004-65-3. Pack Sizes: 500 mg; 1 g. Product ID: HY-A0104. | |
| HPPD-IN-3 | HPPD-IN-3 (compound 25) is a potent inhibitor of 4-Hydroxyphenylpyruvate dioxygenase ( HPPD ), with IC 50 of 10 nM, more potency than Mesotrione (HY-12853) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3024245-46-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161308. | |
| HPPE | HPPE (compound 236) is an orally active, potential Bach1 inhibitor. Bach1 is a transcription factor of the cap'n'collar type alkaline region leucine zipper factor family (CNC-bZip) that regulates mitochondrial metabolism and reduces glucose utilization. HPPE can be used for research in psoriasis, multiple sclerosis, and COPD [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bach1-IN-1. CAS No. 1325721-55-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-153040. | |
| H-Pro-Hyp-OH | H-Pro-Hyp-OH is a collagen peptide composed of proline (Pro) and hydroxyproline (Hyp). H-Pro-Hyp-OH can be used in research on slowing down facial aging [1]. Uses: Scientific research. Group: Peptides. CAS No. 18684-24-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W337672. | |
| HQ461 | HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation. HQ461-mediated degradation of cyclin K impairs CDK12 function, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1226443-41-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144981. | |
| HQNO | HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III[1]. HQNO is a potent inhibitor of mitochondrial NDH-2 in many species[2]. Uses: Scientific research. Group: Natural products. CAS No. 341-88-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-130055. | |
| HRO761 | HRO761 (Werner syndrome RecQ helicase-IN-1) (example 42) is a potent Werner syndrome RecQ DNA helicase enzyme ( WRN ) inhibitor and can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Werner syndrome RecQ helicase-IN-1. CAS No. 2869954-34-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-148699. | |
| HRS-4642 | HRS-4642 is a selective KRAS(G12D) inhibitor (Kd=0.083 nM) with anti-cancer activity. HRS-4642 synergizes with Carfilzomib (HY-10455) and exhibits significant in vivo potency to reshape the tumor microenvironment into an immune-activating microenvironment. Uses: Scientific research. Group: Signaling pathways. CAS No. 2836263-09-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159127. | |
| HRX-0233 | HRX-0233 is a small-molecule MAP2K4 inhibitor. HRX-0233 results in strong tumor shrinkage without any apparent toxicity in H358 KRASG12C-mutant non-small cell lung cancers (NSCLC) in vivo. HRX-0233 efficiently prevents feedback activation of receptor tyrosine kinases (RTKs) upon monotherapy KRAS inhibitor Sotorasib (HY-114277) and causes a more sustained and complete inhibition of MAPK signaling. HRX-0233 is promising for research of AR-negative prostate cancer, lung and colon cancers[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2409140-12-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159190. | |
| HS148 | HS148 (compound 22) is a selective DAPK3 inhibitor with an K i value of 119 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1892595-16-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117364. | |
| HS-27 | HS-27, a fluorescently-tethered Hsp90 inhibitor, assays surface Hsp90 expression on intact tissue specimens. HS-27 is made up of the core elements of SNX-5422, an Hsp90 inhibitor, tethered via a PEG linker to a fluorescein derivative (fluorescein isothiocyanate or FITC), that binds to ectopically expressed Hsp90. HS-27 has potential use in a see-and-treat paradigm in breast cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1562024-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130851. | |
| HS-276 | HS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a Ki of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2, MAP4K5, IRAK1, NUAK, CSNK1G2, CAMKK?-1, and MLK1, with IC50 values of 8.25, 29, 33, 63, 125, 264, 270, 810, 1280, and 5585 nM, respectively. HS-276 can be used for rheumatoid arthritis (RA) research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2767422-72-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147141. | |
| H-Ser(tBu)-OMe.HCl | H-Ser(tBu)-OMe.HCl is a serine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 17114-97-5. Pack Sizes: 10 g; 25 g; 100 g; 500 g. Product ID: HY-W009770. | |
| HSF1A | HSF1A is a cell-permeable activator of heat shock transcription factor 1 (HSF1)[1]. HSF1A also acts as a specific inhibitor of TRiC/CCT. Chaperonin TCP-1 ring complex (TRiC)/chaperonin containing TCP-1 (CCT) plays a pivotal role in toxin translocation and/or refolding[4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1196723-93-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103000. | |
| HSL-IN-1 | HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095156-13-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101509. | |
| hSMG-1 inhibitor 11e | hSMG-1 inhibitor 11e is a potent and selective hSMG-1 kinase inhibitor with an IC50 of <0.05 nM. hSMG-1 inhibitor 11e shows>900-fold selectivity over mTOR (IC50 of 45 nM), PI3K?/? (IC50s of 61 nM and 92 nM) and CDK1/CDK2 (IC50s of 32 ?M and 7.1 ?M)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1402452-10-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124760. | |
| hSMG-1 inhibitor 11j | hSMG-1 inhibitor 11j, a pyrimidine derivative, is a potent and selective inhibitor of hSMG-1, with an IC50 of 0.11 nM. hSMG-1 inhibitor 11j exhibits >455-fold selectivity for hSMG-1 over mTOR (IC50=50 nM), PI3K?/? (IC50=92/60 nM) and CDK1/CDK2 (IC50=32/7.1 ?M). hSMG-1 inhibitor 11j can be used for the research of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1402452-15-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124719. | |
| Hsp110-STAT3 interaction-IN-1 | Row174336 (compound 29) is a potent inhibitor of Hsp110-STAT3 interaction that shows antiproliferative activity against HPAEC cell line, with the IC 50 of 22.67 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 882582-26-5. Pack Sizes: 1 mg. Product ID: HY-Q43097. | |
| HSP27 inhibitor J2 | HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. HSP27 inhibitor J2 (J2) remarkably enhances the antiproliferative activity of 17-AAG and sensitizes cisplatin-induced lung cancer cell growth inhibition[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: J2. CAS No. 2133499-85-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124653. | |
| Hsp90-IN-17 hydrochloride | Hsp90-IN-17 (Example 5) hydrochloride is an HSP90 inhibitor that can be used in the study of proliferative diseases, such as cancer and neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1253584-63-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148215A. | |
| HSP90-IN-22 | HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor with antiproliferative properties on cells with IC 50 values of 3.65 μM for MCF7 breast cancer cells and 2.71 μM for SKBr3 breast cancer cells, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 442898-75-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153588. | |
| HSV-gB2 (498-505) | HSV-gB2 (498-505) is an immunodominant epitope from herpes simplex virus (HSV) glycoprotein B residues 498-505, acts as H-2Kb-restricted and HSV-1/2-cross-reactive cytotoxic T-lymphocyte (CTL) recognition epitope [1]. Uses: Scientific research. Group: Peptides. CAS No. 149997-91-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1862. | |
| HT-2157 | HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonists of galanin-3 receptor (Gal3). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNAP 37889. CAS No. 303149-14-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100717. | |
| HTBA | HTBA(3-Hydroxy-2,4,6-triiodobenzoic acid) for your research needs. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 53279-72-4. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-15919. | |
| HTH-01-015 | HTH-01-015 is a selective NUAK1/ARK5 inhibitor (IC50 is 100 nM). HTH-01-015 inhibits NUAK1 with >100-fold higher potency than NUAK2 (IC50 of >10 ?M). Uses: Scientific research. Group: Signaling pathways. CAS No. 1613724-42-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12334. | |
| H-Thr(tBu)-OMe.HCl | H-Thr(tBu)-OMe.HCl is a threonine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 71989-43-0. Pack Sizes: 10 g; 25 g; 100 g. Product ID: HY-W042013. | |
| HTS07545 | HTS07545 is a potent sulfide:quinone oxidoreductase (SQOR) inhibitor with an IC50 of 30 nM. HTS07545 reduces the decomposition rate of hydrogen sulfide (H2S). HTS07545 can be used in the research of heart failure and pancreatic ductal adenocarcinoma. Uses: Scientific research. Group: Signaling pathways. CAS No. 118666-03-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144439. | |
| H-Tyr-Tyr-OH | H-Tyr-Tyr-OH (L-Tyrosyl-L-tyrosine) is an antihypertensive peptide. H-Tyr-Tyr-OH inhibits angiotensin I-converting enzyme ( ACE ) with an IC 50 value of 0.028 mg/mL. H-Tyr-Tyr-OH can be used for the research of high blood pressure [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-Tyrosyl-L-tyrosine. CAS No. 1050-28-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-114782. | |
| Hu7691 | Hu7691 is an orally active, selective Akt inhibitor with IC 50 s of 4.0 nM, 97.5 nM, 28 nM for Akt1, Akt2 and Akt3, respectively. Hu7691 inhibits tumor growth and enables decrease of cutaneous toxicity in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2360523-76-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-132302. | |
| HUHS015 | HUHS015 is a potent prostate cancer antigen-1 (PCA-1/ALKBH3) inhibitor with an IC50 of 0.67?M for PCA-1[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1453097-13-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100199. | |
| Human α-Thrombin | Human α-thrombin is a multifunctional serine protease that plays a pivotal role in the coagulation pathway. Human α-thrombin cleaves fibrinogen and converts it into fibrin. Human α-thrombin can stimulate platelet activation and stabilize fibrin polymers [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 3.4.21.5; Human Alpha Thrombin. CAS No. 9002-4-4. Pack Sizes: 50 U; 100 U. Product ID: HY-114164A. | |
| Human β-defensin-1 | Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by all epithelial surfaces, but also by circulatory cells and cells of the reproductive tract. Human β-defensin-1 has antimicrobial activities against a broad-sperm bacteria [1]. Uses: Scientific research. Group: Peptides. Alternative Names: HβD-1. CAS No. 452274-53-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2315. | |
| human GIP(3-30), amide | Human GIP(3-30), amide is a high affinity antagonist of the human GIP receptor in vitro. Human GIP(3-30), amide has potential anti-obesity and anti-diabetic effects[1][2]. Uses: Scientific research. Group: Peptides. CAS No. 1884226-05-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P10138. | |
| human GIP(3-30), amide TFA | Human GIP(3-30), amide TFA is the TFA salt form of human GIP(3-30), amide (HY-P10138). Human GIP(3-30), amide TFA is a high affinity antagonist of the human GIP receptor in vitro. Human GIP(3-30), amide TFA has potential anti-obesity and anti-diabetic effects[1][2]. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10138A. | |
| Human IgG1(D356E/L358M) kappa, Isotype Control | Human IgG1(D356E/L358M) kappa, Isotype Control, a human-derived monoclonal antibody, is an isotype control for human IgG1(D356E/L358M)? antibody[1]. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990100. | |
| Human IgG1 (K214R) kappa, Isotype Control | Human IgG1 (K214R) kappa, Isotype Control, a human-derived antibody, is an isotype control for human IgG1 (K214R)? antibody. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99995. | |
| Human IgG1 kappa, Isotype Control | Human IgG1 kappa, Isotype Control is a human monoclonal antibody that is the isotype control of human IgG1 kappa antibody[1]. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99001. | |
| Human IgG1 lambda1, Isotype Control | Human IgG1 lambda1, Isotype Control, a human-derived antibody, is an isotype control for human IgG1?1 antibody. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P99992. | |
| Human IgG1 lambda2, Isotype Control | Human IgG1 lambda2, Isotype Control is a human monoclonal antibody that is the isotype control of human IgG1? antibody. Isotype control antibodies can help remove non-specific signals from experimental results and assess the accuracy and reliability of the experiment[1]. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990096. | |
| Human IgG1 (N297A) kappa, Isotype Control | Human IgG1 (N297A) kappa, Isotype Control, a human-derived antibody, is an isotype control for human IgG1 (N297A)? antibody. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99994. | |
| Human IgG2 kappa, Isotype Control | Human IgG2 kappa, Isotype Control, a human monoclonal antibody, is an isotype control for human IgG2? antibody[1]. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 500 ?g; 1 mg; 5 mg; 10 mg. Product ID: HY-P99002. | |
| Human IgG4 (S228P) kappa, Isotype Control | Human IgG4 (S228P) kappa, Isotype Control, a human-derived monoclonal antibody, is an isotype control for human IgG4? antibody. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99003. | |
| Humanin | Humanin, an anti-apoptotic peptide of 24 amino acids, is a Bax inhibitor. Humanin prevents the translocation of Bax from cytosol to mitochondria, blocks Bax from the inactive to active conformation. Humanin is a mitochondria-associated peptide with a neuroprotective effect against AD-related neurotoxicity. Humanin also improves overall insulin sensitivity in animal. Humanin are related to aging [1] [2]. Humanin analogue, in which the serine at position 14 is replaced by glycine, names HNG [2]. Uses: Scientific research. Group: Peptides. CAS No. 330936-69-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1928. | |
| Human milk lysozyme | Human milk lysozyme is the lysozyme found in human milk. Human milk lysozyme is thought to be a key defense factor in protecting the gastrointestinal tract of newborns against bacterial infection [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 12671-19-1. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-P3021. | |
| Human Papillomavirus (HPV) E7 protein (49-57) | Human Papillomavirus (HPV) E7 protein (49-57) is the H-2 d -restricted human papillomavirus (HPV) E7 49-57 epitope (short peptide spanning the 49th to 57th amino acid residues in the E7 protein) [1]. Uses: Scientific research. Group: Peptides. CAS No. 151812-18-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1907. | |
| Human PD-L1 inhibitor I | Human PD-L1 inhibitor I is a hPD-1 peptide ligand, with a K D of 3.39 μM. Human PD-L1 inhibitor I may disturb the binding of hPD-L1 to hPD-1 [1]. Uses: Scientific research. Group: Peptides. CAS No. 2135542-86-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2474. | |
| Human PTHrP-(1-36) | Human PTHrP-(1-36) is a secretory form of PTHrP with anticalciuric effects. Human PTHrP-(1-36) enhances beta cell function and proliferation. Human PTHrP-(1-36) can be used in the research of humoral hypercalcemia of malignancy (HHM) and hyperparathyroidism[1][3]. Uses: Scientific research. Group: Peptides. CAS No. 172867-62-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-106288. | |
| Human serum albumin | Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB , NF-κB , and peroxynitrite (ONOO - ) in the vascular wall, contributing to the reduction of blood pressure [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: HSA. CAS No. 70024-90-7. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 1 mg. Product ID: HY-P1956. | |
| Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) | Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-?B, iNOS, and peroxynitrite (ONOO?) in the vascular wall, contributing to the reduction of blood pressure[1][2][3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: HSA (Cell culture grade, Endotoxin<0.125 EU/mg). CAS No. 70024-90-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-P1956A. | |
| Humic acid | Humic acid is an important component of organic matter in soil and water. Humic acid enhances pyrene degradation. Humic acid inhibits extracellular polysaccharides (EPS) secretion under high levels of iron conditions and ultimately inhibits colony formation of Microcystis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1415-93-6. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N13022. | |
| Humulone | Humulone (α-Lupulic acid), a prenylated phloroglucinol derivative, is a potent cyclooxygenase-2 (COX-2) inhibitor. Humulone acts as a positive modulator of GABA A receptor at low micromolar concentrations. Humulone is an inhibitor of bone resorption. Humulone possesses antioxidant, anti-angiogenic and apoptosis -inducing properties [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: α-Lupulic acid. CAS No. 26472-41-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N6084. | |
| (-)-Huperzine A | (-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata , with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE) , with an IC 50 of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimers disease [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Huperzine A. CAS No. 102518-79-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-17387. | |
| (±)-Huperzine A | (±)-Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). Uses: Scientific research. Group: Natural products. CAS No. 120786-18-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-17388. | |
| Huperzine B | Huperzine B is a Lycopodium alkaloid isolated from Huperzia serrata and a highly selective acetylcholinesterase (AChE) inhibitor. Huperzine B can be uesd to can be used to improve Alzheimer's disease [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 103548-82-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N2043. | |
| hVEGF-IN-3 | hVEGF-IN-3 (compound 9) is a potent hVEGF inhibitor. hVEGF-IN-3 inhibits HT-29, MCF-7, and HEK-293 cells proliferation with IC 50 s of 61, 142, and 114 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 46739-60-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-160811. | |
| HX531 | HX531 is an orally active RXR antagonist with an IC50 of 18 nM. HX531 upregulates the p53-p21Cip1 pathway. HX531 abrogates the anti-apoptotic effect of t-RA. HX531 exerts anti-obesity, anti-diabetic and anti-melanoma activities[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 188844-34-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-108521. | |
| HX600 | HX600 is a synthetic agonist for RXR (Retinoid X Receptor) heterodimer complex. HX600 prevents ischemia-induced neuronal damage. HX600 has orally bioactivity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 172705-89-4. Pack Sizes: 1 mg. Product ID: HY-120875. | |
| Hyaluronic acid | Hyaluronic acid (corn fermented) is a biopolymer composed of repeating units of disaccharides with various applications. Uses: Scientific research. Group: Natural products. Alternative Names: Hyaluronan; Hyaluronate. CAS No. 9004-61-9. Pack Sizes: 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-B0633A. | |
| Hyaluronic acid sodium | Hyaluronic acid sodium (Sodium hyaluronate) is a biopolymer composed of repeating units of disaccharides with various applications. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium hyaluronate. CAS No. 9067-32-7. Pack Sizes: 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-B0633. | |
| Hyaluronidase, Bovine testes | Hyaluronidase, Bovine testes (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is an endoglycosidase that depolymerizes Hyaluronic acid ( HA ) (HY-B0633A) by cleavage of glycosidic bonds. Hyaluronidase degrades HA and activates membrane receptors that trigger pathways converging in NF-κB activation. Hyaluronidase is employed in the research of granulomatous foreign body reactions, soft-tissue necrosis caused by vascular compromise and uncomplicated nodules, overcorrection, inflamed nodules or tissue ischemia associated with HA filler injection [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hyaluronate 4-glycanohydrolase, Bovine testes; Hyaluronoglucosaminidase, Bovine testes. CAS No. 37326-33-3. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-107910. | |
| Hyaluronidase (human recombinant) | Hyaluronidase (human recombinant) (Hylenex; Vorhyaluronidase alfa; rHuPH 20) is an enzyme that catalyzes the degradation of hyaluronic acid. Hyaluronidase (human recombinant) is used to improve the absorption and dispersal of parenteral fluids, medications, and contrast media [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hylenex; Vorhyaluronidase alfa; rHuPH 20. CAS No. 37326-33-3. Pack Sizes: 150 U. Product ID: HY-108903. | |
| Hyaluronidase, Ovine testes | Hyaluronidase, Ovine testes is an enzyme responsible for catalyzing the degradation of hyaluronic acid. It is used to improve the absorption and dispersion of gastrointestinal fluids, drugs, and contrast agents. Hyaluronidase, Ovine testes can enhance the diffusion or delivery of local agent (LA) that can suppress or relieve pain or immunoglobulins (Igs) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 37326-33-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108903A. | |
| Hycanthone | Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a K D of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3105-97-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1099. | |
| Hydralazine hydrochloride | Hydralazine hydrochloride is an antihypertensive agent. Hydralazine hydrochloride can inhibit mitochondrial fission and human peritoneal mesothelial cell proliferation. Hydralazine hydrochloride has immunomodulation and anti-migratory effect. Hydralazine hydrochloride activates the intrinsic pathway of apoptosis and causes DNA damage [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304-20-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0464. | |
| Hydrastine | Hydrastine is a natural alkaloid found in Hydrastis canadensis and other plants of the Ranunculaceae family. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-β-Hydrastine; (1R,9S)-β-Hydrastine. CAS No. 118-08-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-B0927. | |
| Hydrastinine | Hydrastinine is a major alkaloid constituent in goldenseal ( Hydrastis canadensis ). Hydrastinine can be used as a haemostatic agent [1]. Uses: Scientific research. Group: Natural products. CAS No. 6592-85-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1181A. | |
| Hydrastinine hydrochloride | Hydrastinine hydrochloride is a major alkaloid constituent in goldenseal ( Hydrastis canadensis ). Hydrastinine hydrochloride can be used as a haemostatic agent [1]. Uses: Scientific research. Group: Natural products. CAS No. 4884-68-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1181. | |
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