MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
Laminin β2 (Engelbreth-Holm-Swarm murine sarcoma basement membrane) is a crucial structural element in animal tissues, forming part of the scaffolding that supports tissue architecture. It interacts with type IV collagen through entactin and perlecan, connects to cell membranes via integrin receptors, dystroglycan complexes, and Lutheran blood group glycoproteins, and contains functional domains that facilitate collagen binding, cell adhesion, heparin interaction, and promote neurite outgrowth. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Mouse laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane). CAS No. 114956-81-9. Pack Sizes: 1 mg. Product ID: HY-P2975.
Lamivudine
Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BCH-189. CAS No. 134678-17-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0250.
Lamivudine (Standard)
Lamivudine (Standard) is the analytical standard of Lamivudine. This product is intended for research and analytical applications. Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BCH-189 (Standard). CAS No. 134678-17-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0250R.
Lamotrigine
Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na + channels , stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LTG; BW430C. CAS No. 84057-84-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0495.
Lamotrigine (Standard)
Lamotrigine (Standard) is the analytical standard of Lamotrigine. This product is intended for research and analytical applications. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na + channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 84057-84-1. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-B0495R.
Lampalizumab
Lampalizumab (RG 7417) is a humanised monoclonal antibody targeting complement Factor D in the alternative complement pathway. Lampalizumab binds an exosite and sterically blocks Factor B access to the active site. Lampalizumab can be used for age-related macular degeneration (AMD) research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RG 7417; TNX 234; Anti-CFD Recombinant Antibody. CAS No. 1278466-20-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99298.
Lanabecestat
Lanabecestat (AZD3293) is a potent, orally active and blood-brain barrier penetrating BACE1 inhibitor with a K i of 0.4 nM. Lanabecestat is used for the research of Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD3293; LY3314814. CAS No. 1383982-64-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100740.
Lanadelumab
Lanadelumab (SHP643) is a human IgG1 monoclonal antibody against plasma kallikrein (pKal) with an K i value of 0.12 nM. Lanadelumab inhibits both free and HMWK (high molecular weight kininogen)-bound pKal. Lanadelumab has the potential for the research of hereditary angioedema [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SHP643; DX-2930. CAS No. 1426055-14-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99110.
Landiolol hydrochloride
Landiolol hydrochloride (ONO1101 hydrochloride) is a highly beta1 selective ultra-short acting beta -blocker (β1/β2 selectivity?=?255:1, a half-life of 4?min), acts as an adrenoceptor antagonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ONO1101 hydrochloride. CAS No. 144481-98-1. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100607A.
Landipirdine
Landipirdine is a selective antagonist of 5-HT 6 R. Landipirdine has great effect on the hERG pharmacophore [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO5025181; SYN120. CAS No. 1000308-25-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109036.
Lanicemine dihydrochloride
Lanicemine (AZD6765) dihydrochloride is a low-trapping NMDA channel blocker ( K i of 0.56-2.1 μM for NMDA receptor; IC 50 s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD6765 dihydrochloride; ARL 15896AR. CAS No. 153322-06-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108235A.
Laninamivir
Laninamivir (R 125489) is a potent influenza neuraminidase (NA) inhibitor with IC 50 s of 0.90 nM, 1.83 nM and 3.12 nM for avian H12N5 NA (N5), pH1N1 N1 NA (p09N1) and A/RI/5+/1957 H2N2 N2 (p57N2), respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 125489. CAS No. 203120-17-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14818.
Laninamivir octanoate
Laninamivir octanoate (CS-8958), a proagent of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Laninamivir octanoate shows anti-influenza activity against Oseltamivir-resistant viruses, and also against the pandemic influenza viruses [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CS-8958. CAS No. 203120-46-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14818A.
Lanolin
Lanolin is a yellow fat obtained from sheep's wool. Lanolin is used topically for sore, cracked nipples during breastfeeding [1]. Uses: Scientific research. Group: Natural products. CAS No. 8006-54-0. Pack Sizes: 500 mg. Product ID: HY-N7074.
Lanosterol
Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol suppresses the aggregation and cytotoxicity of misfolded proteins linked with neurodegenerative diseases [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 79-63-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W020033.
Lanosterol-d6
Lanosterol-d 6 is deuterium labeled Lanosterol. Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol s. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 28290-39-3. Pack Sizes: 100 μg; 1 mg. Product ID: HY-W020033S.
Lanperisone hydrochloride
Lanperisone hydrochloride is a novel oral muscle relaxant with anticancer activity. Lanperisone hydrochloride produces non-apoptotic cell death by inhibiting monosynaptic and polysynaptic reflex potentials. Lanperisone hydrochloride is also believed to play an important role in the dysregulation of iron metabolism and antioxidant systems to modulate processes associated with ischemic stroke [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 116287-13-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-119325A.
Lanreotide acetate
Lanreotide (BIM 23014) acetate is a somatostatin analogue with antineoplastic activity. Lanreotide acetate can be used for the research of carcinoid syndrome [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: BIM 23014 acetate. CAS No. 2378114-72-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1959A.
L-Anserine nitrate
L-Anserine nitrate is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 10030-52-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011393.
Lansoprazole
Lansoprazole (AG 1749) is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole (AG 1749) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-1749. CAS No. 103577-45-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-13662.
Lansoprazole sulfone
Lansoprazole sulfone (AG-1813) is an orally active and selective inhibitor of H + , K + -ATPase. Lansoprazole sulfone can significantly stimulates gastric acid secretion by inhibiting H + , K + -ATPase. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-1813. CAS No. 131926-99-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W008614.
LAP
LAP (Lithium phenyl-2,4,6-trimethylbenzoylphosphinate) is a free radical initiator. The free radicals produced by LAP under bioprinting conditions are potentially cytotoxic and mutagenic. In addition, the concentration of LAP affects the mechanical strength of 3D printed scaffolds. Generally, the concentration range of LAP used for curing is 0.05%-1%. The elastic modulus produced at a concentration of 0.1% is the highest, with enhanced mechanical properties and excellent biocompatibility [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Lithium phenyl-2,4,6-trimethylbenzoylphosphinate. CAS No. 85073-19-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-44076.
L-AP4
L-AP4 (L-APB) is a potent and specific agonist for the group III mGluRs , with EC 50 s of 0.13, 0.29, 1.0, 249 μM for mGlu 4 , mGlu 8 , mGlu 6 and mGlu 7 receptors, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-APB. CAS No. 23052-81-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-100781A.
Lapachol
Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 84-79-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N6961.
Lapatinib
Lapatinib (GW572016) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC 50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW572016; GW2016. CAS No. 231277-92-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50898.
Lapatinib ditosylate
Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC 50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW572016 ditosylate; GW2016 ditosylate. CAS No. 388082-77-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50898A.
Lapatinib ditosylate monohydrate
Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC 50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW572016 ditosylate monohydrate; GW2016 ditosylate monohydrate. CAS No. 388082-78-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-50898B.
Laquinimod
Laquinimod (ABR-215062), an orally available carboxamide derivative, is a potent immunomodulator which prevents neurodegeneration and inflammation in the central nervous system. Laquinimod reduces astrocytic NF-κB activation to protect from Cuprizone-induced demyelination. Laquinimod has the potential for relapsing remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative diseases research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABR-215062. CAS No. 248281-84-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13010.
L-Arabinitol
L-Arabinitol is a potential biomarker for the comsuption of the food products such as sweet potato, deerberry, moth bean, and is also associated with Alzheimer's disease and ribose-5-phosphate isomerase deficiency. Uses: Scientific research. Group: Natural products. CAS No. 7643-75-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-W040141.
L-Arabinitol (Standard)
L-Arabinitol (Standard) is the analytical standard of L-Arabinitol. This product is intended for research and analytical applications. L-Arabinitol is a potential biomarker for the comsuption of the food products such as sweet potato, deerberry, moth bean, and is also associated with Alzheimer's disease and ribose-5-phosphate isomerase deficiency. Uses: Scientific research. Group: Natural products. CAS No. 7643-75-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W040141R.
L-(+)-Arabinose
L-(+)-Arabinose selectively inhibits intestinal sucrase activity in a noncompetitive manner and suppresses the plasma glucose increase due to sucrose ingestion. Uses: Scientific research. Group: Natural products. CAS No. 5328-37-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W015611.
Larazotide
Larazotideis a peptide which is an orally active zonulin antagonist. Larazotide shows antiviral activity to varicella-zoster virus (VZV) with EC 50 s of 44.14 and 59.06 μM for strain OKA and 07-1, respectively. Larazotide can be used for the research of celiac disease and infection [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 258818-34-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-106268.
Larazotide acetate
Larazotide acetate is a peptide which is an orally active zonulin antagonist. Larazotide acetate shows antiviral activity to varicella-zoster virus (VZV) with EC 50 s of 44.14 and 59.06 μM for strain OKA and 07-1, respectively. Larazotide acetate can be used for the research of celiac disease and infection. Uses: Scientific research. Group: Peptides. CAS No. 881851-50-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106268A.
L-Arginine
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 74-79-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N0455.
L-Arginine-13C6,15N4 hydrochloride
L-Arginine- 13 C 6 , 15 N 4 (hydrochloride) is the 13 C- and 15 N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (S)-(+)-Arginine- 13 C6, 15 N4 hydrochloride. CAS No. 202468-25-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0455AS8.
L-Arginine-13C6 hydrochloride
L-Arginine- 13 C 6 (hydrochloride) is the 13 C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (S)-(+)-Arginine- 13 C6 hydrochloride. CAS No. 201740-91-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0455AS6.
L-Arginine-13C hydrochloride
L-Arginine- 13 C (hydrochloride) is the 13 C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (S)-(+)-Arginine- 13 C hydrochloride. CAS No. 94740-43-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0455AS7.
L-Arginine-15N2 hydrochloride
L-Arginine- 15 N 2 (hydrochloride) is the 15 N-labeled L-Arginine (hydrochloride). L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (S)-(+)-Arginine- 15 N2 hydrochloride. CAS No. 204633-92-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0455AS.
L-Arginine-15N4 hydrochloride
L-Arginine- 15 N 4 (hydrochloride) is the 15 N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (S)-(+)-Arginine- 15 N4 hydrochloride. CAS No. 204633-95-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0455AS1.
L-Arginine-7-amido-4-methylcoumarin hydrochloride
L-Arginine-7-amido-4-methylcoumarin (Arginine 4-methyl-7-coumarylamide) hydrochloride is a specific substrate of cathepsin H but not for cathepsins L and B [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Arginine 4-methyl-7-coumarylamide hydrochloride. CAS No. 69304-16-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-137841.
L-Arginine butanoate
L-Arginine butanoate ((S)-(+)-Arginine butanoate) is a compound consisting of L-Arginine and butanoate. L-Arginine is one of the essential nutrients in the human body and participates in various biochemical processes. Butanoate is a short-chain fatty acid commonly used as a food additive and solvent in pharmaceutical formulations [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-(+)-Arginine butanoate. CAS No. 80407-72-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0455D.
L-Arginine hydrochloride
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-(+)-Arginine hydrochloride. CAS No. 1119-34-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N0455A.
L-Arginine (Standard)
L-Arginine (Standard) is the analytical standard of L-Arginine. This product is intended for research and analytical applications. L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 74-79-3. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N0455R.
Lariciresinol
Lariciresinol is an orally active ingredient. Lariciresinol can be isolated from Arabidopsis thaliana. Lariciresinol inhibits α-glucosidase activity ( IC 50 of 6.97 μM; K i of 0.046 μM). Lariciresinol dereases Bcl-2 , upregulates Bax and induces Apoptosis ?Lariciresinol regulates TGF-β and NF-κB pathways. Lariciresinol has antitumor activity against liver cancer, gastric cancer, and breast cancer. Lariciresinol shows antifungal activity and anti-diabetic activity [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. CAS No. 27003-73-2. Pack Sizes: 1 mg. Product ID: HY-N3405.
Larixyl acetate
Larixyl acetate is a potent and selective TRPC6 inhibitor with IC 50 values of 0.58 μM and 6.83 μM against hTRPC6-YFP and hTRPC3-YFP , respectively. Larixyl acetate prevents HPV and is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 4608-49-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101795.
Laropiprant
Laropiprant is a potent and selective DP receptor antagonist with K i values of 0.57 nM and 2.95 nM for DP receptor and TP Receptor, respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0524. CAS No. 571170-77-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50175.
Larotaxel
Larotaxel (XRP9881) is a taxane analogue with preclinical activity against taxane-resistant breast cancer. Larotaxel (XRP9881) exerts its cytotoxic effect by promoting tubulin assembly and stabilizing microtubules, ultimately leading to cell death by apoptosis. It presents the ability to cross the blood brain barrier and has a much lower affinity for P-glycoprotein 1 than Docetaxel [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XRP9881. CAS No. 156294-36-9. Pack Sizes: 1 mg. Product ID: HY-125374.
Larotrectinib
Larotrectinib (LOXO-101) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C). Uses: Scientific research. Group: Signaling pathways. Alternative Names: LOXO-101; ARRY-470. CAS No. 1223403-58-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12866.
Larotrectinib sulfate
Larotrectinib sulfate (LOXO-101 sulfate; ARRY-470 sulfate) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C). Uses: Scientific research. Group: Signaling pathways. Alternative Names: LOXO-101 sulfate; ARRY-470 sulfate. CAS No. 1223405-08-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12866A.
Lartesertib
Lartesertib (M4076) is a potent inhibitor of serine/threonine protein kinase ATM (extracted from patent WO2022058351A1) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M4076; ATM Inhibitor-5. CAS No. 2495096-26-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150617.
Lasalocid
Lasalocid (Lasalocid-A; Ionophore X-537A; Antibiotic X-537A) is an antibacterial and anticoccidial agent used in feed additives. Uses: Scientific research. Group: Natural products. Alternative Names: Lasalocid-A; Ionophore X-537A; Antibiotic X-537A. CAS No. 25999-31-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1071.
Lasalocid sodium
Lasalocid sodium (Lasalocid-A sodium) is an antibacterial agent. Uses: Scientific research. Group: Natural products. Alternative Names: Lasalocid-A sodium; Ionophore X-537A sodium; Antibiotic X-537A sodium. CAS No. 25999-20-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1071A.
Lasamide
Lasamide is a potent human Carbonic Anhydrase inhibitor with K i values of 7.54 and 2.76 nM for hCAXII and hCAIX, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2736-23-4. Pack Sizes: 25 g. Product ID: HY-W013316.
L-Ascorbic acid
L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Ca v 3.2 channels with an IC 50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor [1] [2] [3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species ( ROS ) and selective damage to cancer cells [4]. Uses: Scientific research. Group: Natural products. Alternative Names: L-Ascorbate; Vitamin C. CAS No. 50-81-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0166.
L-Ascorbic acid-13C
L-Ascorbic acid- 13 C is the 13 C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: L-Ascorbate- 13 C; Vitamin C- 13 C. CAS No. 178101-88-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0166S1.
L-Ascorbic acid-13C6
L-Ascorbic acid- 13 C 6 is the 13 C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: L-Ascorbate- 13 C6; Vitamin C- 13 C6. CAS No. 1354064-87-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0166S.
L-Ascorbic acid 2-phosphate magnesium hydrate
L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) magnesium hydrate is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate magnesium hydrate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate magnesium hydrate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Phospho-L-ascorbic acid magnesium hydrate. CAS No. 1713265-25-8. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-103701B.
L-Ascorbic acid 2-phosphate trisodium
L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression [1]. L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Phospho-L-ascorbic acid trisodium. CAS No. 66170-10-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-107837.
L-Ascorbic acid (Standard)
L-Ascorbic acid (Standard) is the analytical standard of L-Ascorbic acid. This product is intended for research and analytical applications. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Ca v 3.2 channels with an IC 50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor [1] [2] [3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species ( ROS ) and selective damage to cancer cells [4]. Uses: Scientific research. Group: Natural products. CAS No. 50-81-7. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-B0166R.
Lascufloxacin
Lascufloxacin (KRP-AM1977X) is a potent and orally active fluoroquinolone antibacterial agent. Lascufloxacin potently inhibits infections caused by various pathogens, including quinolone-resistant strains. Lascufloxacin has the potential for various infectious diseases treatment, including lower respiratory tract infections [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KRP-AM1977. CAS No. 848416-07-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-16745.
Lasofoxifene
Lasofoxifene (CP-336156) is an orally active and selective estrogen receptor modulator ( SERM ). Lasofoxifene exhibits an anti-osteoporotic function and also inhibits primary tumor growth and metastases. Lasofoxifene can be used for research of breast cancer and postmenopausal osteoporosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-336156. CAS No. 180916-16-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-A0037.
Lasofoxifene tartrate
Lasofoxifene (CP-336156) tartrate is an orally active and selective estrogen receptor modulator ( SERM ) [1]. Lasofoxifene tartrate exhibits an anti-osteoporotic function and also inhibits primary tumor growth and metastases. Lasofoxifene tartrate can be used for the research of breast cancer and postmenopausal osteoporosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-336156 tartrate. CAS No. 190791-29-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-A0038.
L-Asparaginase
L-Asparaginase (L-ASNase) is a deamidating enzyme that catalyses the hydrolysis of L-asparagine and L-glutamine, and can be used for the research of acute lymphoblastic leukemia. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-ASNase. CAS No. 9015-68-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P1923.
L-Asparagine
L-Asparagine ((-)-Asparagine) is a non-essential amino acid involved in the metabolic control of nerve and brain tissue cell function. L-Asparagine has antitumor activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Asparagine; Asn; Asparamide. CAS No. 70-47-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0667.
L-Asparagine-13C4,15N2 monohydrate
L-Asparagine- 13 C 4 , 15 N 2 (monohydrate)is the 13 C-labeled and 15 N-labeled L-Asparagine monohydrate. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 202406-87-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W017443S.
L-Asparagine-amide-15N monohydrate
L-Asparagine-amide- 15 N (monohydrate) is the 15 N-labeled L-Asparagine (monohydrate). L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 204451-47-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W017443S1.
L-Asparagine monohydrate
L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. Uses: Scientific research. Group: Natural products. CAS No. 5794-13-8. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-W017443.
L-Asparagine (Standard)
L-Asparagine (Standard) is the analytical standard of L-Asparagine. This product is intended for research and analytical applications. L-Asparagine ((-)-Asparagine) is a non-essential amino acid involved in the metabolic control of nerve and brain tissue cell function. L-Asparagine has antitumor activity [1] [2] [3]. In Vitro: L-Asparagine (0.03 mM) can reverse the proliferation decline of six human cancer cells induced by ASNS siRNA knockdown [2]. L-Asparagine (10 mM, 4 h) can stimulate ODC activity and proliferation in IPEC-J2 cells [3]. Uses: Scientific research. Group: Natural products. CAS No. 70-47-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0667R.
L-Aspartic acid
L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly. Uses: Scientific research. Group: Natural products. CAS No. 56-84-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N0666.
L-Aspartic acid-13C4
L-Aspartic acid- 13 C 4 is the 13 C-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 55443-54-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N0666S4.