MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| (-)-Epicatechin | (-)-Epicatechin inhibits cyclooxygenase-1 ( COX-1 ) with an IC 50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Epicatechol; Epicatechin; epi-Catechin. CAS No. 490-46-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0001. |  |
| (-)-Epicatechin gallate | (-)-Epicatechin gallate (Epicatechin gallate) inhibits cyclooxygenase-1 ( COX-1 ) with an IC 50 of 7.5 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Epicatechin gallate; ECG; (-)-Epicatechin 3-O-gallate. CAS No. 1257-08-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0002. | |
| (-)-Epicatechin gallate (Standard) | (-)-Epicatechin gallate (Standard) is the analytical standard of (-)-Epicatechin gallate. This product is intended for research and analytical applications. (-)-Epicatechin gallate (Epicatechin gallate) inhibits cyclooxygenase-1 ( COX-1 ) with an IC 50 of 7.5 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Epicatechin gallate(Standard); ECG(Standard); (-)-Epicatechin 3-O-gallate (Standard). CAS No. 1257-08-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0002R. | |
| (-)-Epicatechin (Standard) | (-)-Epicatechin (Standard) is the analytical standard of (-)-Epicatechin. This product is intended for research and analytical applications. (-)-Epicatechin inhibits cyclooxygenase-1 ( COX-1 ) with an IC 50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Epicatechol(Standard); Epicatechin(Standard); epi-Catechin (Standard). CAS No. 490-46-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0001R. | |
| (-)-Epigallocatechin | (-)-Epigallocatechin (Epigallocatechin) is the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils. Uses: Scientific research. Group: Natural products. Alternative Names: Epigallocatechin; L-Epigallocatechin. CAS No. 970-74-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0225. | |
| (-)-Epigallocatechin Gallate | (-)-Epigallocatechin Gallate (EGCG) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. (-)-Epigallocatechin Gallate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: EGCG; Epigallocatechol Gallate. CAS No. 989-51-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13653. | |
| (-)-Epigallocatechin (Standard) | (-)-Epigallocatechin (Standard) is the analytical standard of (-)-Epigallocatechin. This product is intended for research and analytical applications. (-)-Epigallocatechin (Epigallocatechin) is the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils. Uses: Scientific research. Group: Natural products. Alternative Names: Epigallocatechin(Standard); L-Epigallocatechin (Standard). CAS No. 970-74-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0225R. | |
| epi-Inositol | epi-Inositol is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Ethanol Consumption [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 488-58-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W016509. | |
| Epinastine | Epinastine (WAL801) is an antihistamine and mast cell stabilizer. Epinastine is a potent, selective and orally-active histamine H1 receptor antagonist. Epinastine also inhibits IL-8 release and has an antiallergic action [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WAL801. CAS No. 80012-43-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0640. | |
| Epinastine hydrochloride | Epinastine hydrochloride (WAL801 hydrochloride) is an antihistamine and mast cell stabilizer. Epinastine hydrochloride is a potent, selective and orally-active histamine H1 receptor antagonist. Epinastine hydrochloride also inhibits IL-8 release and has an antiallergic action [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WAL801 hydrochloride. CAS No. 108929-04-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0640A. | |
| (-)-Epipodophyllotoxin | (-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum , with GI 50 s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro [1]. Uses: Scientific research. Group: Natural products. CAS No. 4375-7-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7654. | |
| Epirizole | Epirizole (Mepirizole) is an orally active NSAID (nonsteroidal anti-inflammatory agent). Epirizole shows anti-inflammatory activity, and can be used in chronic rheumatoid arthritis research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mepirizole; DA-398. CAS No. 18694-40-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-103595. | |
| Epirubicin | Epirubicin (4'-Epidoxorubicin), a semisynthetic L-arabino derivative of doxorubicin, has an antineoplastic agent by inhibiting Topoisomerase [1]. Epirubicin inhibits DNA and RNA synthesis. Epirubicin is a Forkhead box protein p3 (Foxp3) inhibitor and inhibits regulatory T cell activity [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4'-Epidoxorubicin. CAS No. 56420-45-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13624. | |
| Epirubicin hydrochloride | Epirubicin hydrochloride (4'-Epidoxorubicin hydrochloride), a semisynthetic L-arabino derivative of doxorubicin, has an antineoplastic agent by inhibiting Topoisomerase [1]. Epirubicin hydrochloride inhibits DNA and RNA synthesis. Epirubicin hydrochloride is a Forkhead box protein p3 (Foxp3) inhibitor and inhibits regulatory T cell activity [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4'-Epidoxorubicin hydrochloride. CAS No. 56390-09-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13624A. | |
| Epirubicin (hydrochloride) (Standard) | Epirubicin (hydrochloride) (Standard) is the analytical standard of Epirubicin (hydrochloride). This product is intended for research and analytical applications. Epirubicin hydrochloride (4'-Epidoxorubicin hydrochloride), a semisynthetic L-arabino derivative of doxorubicin, has an antineoplastic agent by inhibiting Topoisomerase [1]. Epirubicin hydrochloride inhibits DNA and RNA synthesis. Epirubicin hydrochloride is a Forkhead box protein p3 (Foxp3) inhibitor and inhibits regulatory T cell activity [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 56390-09-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13624AR. | |
| Episyringaresinol 4'-O-β-D-glncopyranoside | Episyringaresinol 4'-O-β-D-glncopyranoside (compound 22), isolated from Alhagi sparsifolia Shap, is a natural potential neuroinflammatory inhibitor [1]. Uses: Scientific research. Group: Natural products. CAS No. 137038-13-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2182. | |
| Epitalon | Epitalon is an anti-aging agent and a telomerase activator. Epitalon has an inhibitory effect of the on the development of spontaneous tumors in mice, has geroprotective actions and intranasal administration increases neuronal activity. Epitalon can be used for cancer, old age and Retinitis Pigmentosa [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Epithalon; Epithalamin. CAS No. 307297-39-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1149. | |
| Epitinib succinate | Epitinib succinate is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration. Epitinib succinate can be used for the research of cancer [1] [2]. Epitinib (succinate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HMPL-813 succinate. CAS No. 2252334-12-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139300A. | |
| EPI-X4 | EPI-X4 (hSA408 - 423 peptide) is an antagonist for C-X-C motif chemokine receptor 4 ( CXCR4 ) with IC 50 of 8.6 μM. EPI-X4 blocks the CXCL12-mediated signaling, inhibits chemokine-mediated migration and invasion of leukemia cell. EPI-X4 exhibits anti-inflammatory activity in mouse model. EPI-X4 exhibits antiviral activity against CXCR4-tropic HIV with IC 50 of 8.6 μM [1]. Uses: Scientific research. Group: Peptides. Alternative Names: hSA(408 - 423) peptide. CAS No. 930280-31-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10415. | |
| Eplerenone | Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also is a selective mineralocorticoid receptor antagonist (MRA) with IC 50 value of 0.081 μM. Eplerenone can be used for the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Epoxymexrenone. CAS No. 107724-20-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0251. | |
| Eplontersen sodium | Eplontersen sodium the sodium salt form of Eplontersen (HY-148089). Eplontersen sodium is a triantennary N-acetyl galactosamine (GalNAc3-7a)-conjugated antisense oligonucleotide targeting transthyretin (TTR) mRNA to inhibit production of both variant and wild-type TTR protein. Misfolded TTR induces amyloid fibrils formation in the heart and peripheral nerves, leads to amyloid TTR (ATTR) amyloidosis diseases[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2131025-75-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148089A. | |
| Epoetin beta | Epoetin beta (rhEPO) is a recombinant form of erythropoietin. Epoetin beta is responsible for the maintenance of erythropoiesis and can be used for anaemia research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: rhEPO; EPOCH; Genetical recombination. CAS No. 122312-54-3. Pack Sizes: 500 U; 1000 U; 2000 U; 5000 U. Product ID: HY-114134. | |
| Epoprostenol sodium | Epoprostenol sodium (Prostaglandin I2) sodium salt, the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH). Epoprostenol sodium is used in pulmonary hypertension and transplantation as a potent inhibitor of platelet aggregation [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Prostaglandin I2 sodium salt; Prostacyclin sodium salt; Flolan. CAS No. 61849-14-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0126A. | |
| Epothilone A | Epothilone A is a competitive inhibitor of the binding of [ 3 H] paclitaxel to tubulin polymers, with a K i of 0.6-1.4 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Epo A. CAS No. 152044-53-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13503. | |
| Epothilone B | Epothilone B is a microtubule stabilizer with a K i of 0.71μM. It acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EPO 906; Patupilone. CAS No. 152044-54-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17029. | |
| Epothilone D | Epothilone D (KOS 862) is a potent microtubule stabilizer. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KOS 862. CAS No. 189453-10-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15278. | |
| Epoxiconazole | Epoxiconazole, a fungicide, is a demethylation inhibitor of the Ergosterol biosynthesis pathway. Epoxiconazole exhibits strong inhibitory effects on both carbendazim-resistant and phenamacril-resistant isolates, and can be used for controlling many crop diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133855-98-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119683. | |
| Epoxomicin | Epoxomicin (BU-4061T) is an epoxyketone-containing natural product and a potent, selective and irreversible proteasome inhibitor. Epoxomicin covalently binds to the LMP7, X, MECL1, and Z catalytic subunits of the proteasome and potently inhibits primarily the chymotrypsin-like activity. Epoxomicin can cross the blood-brain barrier. Epoxomicin has strongly antitumor and anti-inflammatory activity [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: BU-4061T. CAS No. 134381-21-8. Pack Sizes: 10 mM * 1 mL; 100 μg; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-13821. | |
| EpoY | EpoY (SD-142) acts as an irreversible inhibitor of the brain's primary tubulin tyrosine carboxypeptidase (TCP), a complex formed by vasohibin-1 (VASH1) and the small vasohibin binding protein (SVBP). By inhibiting TCP with an IC 50 value of approximately 500 nM, EpoY effectively decreases levels of detyrosinated alpha-tubulin, which is crucial for microtubule dynamics and neuronal differentiation. This inhibition leads to significant differentiation defects and has been linked to underlying issues associated with cancer and cardiomyopathies. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SD-142. CAS No. 245660-13-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-148542. | |
| Epratuzumab | Epratuzumab (Antibody hLL 2) is an anti-CD22 IgG1 monoclonal antibody. Epratuzumab is also a tumor-imaging agent and an immunomodulatory agent. Epratuzumab can induce CD22 phosphorylation. Epratuzumab has been used to research non-Hodgkins lymphomas (NHL) and certain autoimmune diseases [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Antibody hLL 2; Anti-Human CD22 Recombinant Antibody. CAS No. 205923-57-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99289. | |
| Eprazinone dihydrochloride | Eprazinone dihydrochloride is a gent with mucolytic, secretolytic, antitussive, and bronchial antispasmodic properties. Eprazinone dihydrochloride is a neurokinin 1 receptor (NK1R) ligand. Eprazinone dihydrochloride has the potential for chronic bronchitis treatment that improved pulmonary function and arterial partial pressure of oxygen [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 10402-53-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B2078A. | |
| Eprenetapopt | Eprenetapopt (APR-246) is a first-in-class, small molecule that restores wild-type p53 functions in TP53 -mutant cells. Eprenetapopt triggers apoptosis in tumor cells. Eprenetapopt also targets the selenoprotein thioredoxin reductase 1 ( TrxR1 ), a key regulator of cellular redox balance [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APR-246; PRIMA-1Met. CAS No. 5291-32-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19980. | |
| Eprinomectin | Eprinomectin (MK-397) is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-397. CAS No. 123997-26-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-12643. | |
| Epristeride | Epristeride (ONO-9302) is a selective, specific and orally active uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2. Epristeride has inhibitory effects for SR isoenzymes types 2 with K i value of 0.7-2 nM. Epristeride can be used for the research of prostatic hyperplasia and acne [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ONO-9302; SKF105657. CAS No. 119169-78-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-107385. | |
| Eprodisate | Eprodisate is an amyloid inhibitor that interferes with the interaction between amyloidogenic proteins and glycosaminoglycans, thereby inhibiting the aggregation of amyloid fibrils and the deposition of fibrils in tissues. Eprodisate slows the progression of renal disease associated with AA amyloidosis and may be useful for other types of amyloidosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 21668-77-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-128849. | |
| Eprodisate disodium | Eprodisate disodium (NC-503) is the orally available disodium salt form of Eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NC-503. CAS No. 36589-58-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1141. | |
| Eprosartan | Eprosartan (SKF-108566J free base) is a selective, competitive, nonpeptid and orally active angiotensin II receptor antagonist, used as an antihypertensive. Eprosartan binds angiotensin II receptor with IC 50 s of 9.2 nM and 3.9 nM in rat and human adrenal cortical membranes, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF-108566J free base. CAS No. 133040-01-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-117743. | |
| Eprosartan mesylate | Eprosartan mesylate (SKF-108566J) is a selective, competitive, nonpeptid and orally active angiotensin II receptor antagonist, used as an antihypertensive. Eprosartan mesylate binds angiotensin II receptor with IC 50 s of 9.2 nM and 3.9 nM in rat and human adrenal cortical membranes, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF-108566J. CAS No. 144143-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15834A. | |
| Eprotirome | Eprotirome (KB2115) is a liver-selective thyroid hormone receptor (TR) agonist. KB2115 has modestly higher affinity for TRβ than for TR&alpha. Eprotirome reduces low-density lipoprotein (LDL) cholesterol concentrations. Eprotirome can be used for dyslipidemias and obesity research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KB2115. CAS No. 355129-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10473. | |
| ε-Caprolactone | ε-Caprolactone is a lactone compound that can be isolated from the Arctic thorn [1]. Uses: Scientific research. Group: Natural products. CAS No. 502-44-3. Pack Sizes: 1 mg. Product ID: HY-W015891. | |
| ε-?Viniferin | ε-Viniferin (epsilon-Viniferin), the dimer of Resveratrol and can be isolated from Vitis vinifera , displays a potent inhibitory for all the CYP activities, with K i values from 0.5-20 μM. ε-Viniferin possesses potent antioxidant, anti-inflammatory, anti-diabetic, and anti-neurodegenerative capacity [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: epsilon-Viniferin. CAS No. 62218-08-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3841. | |
| Eptifibatide | Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor , with anti-platelet activity [1]. Uses: Scientific research. Group: Peptides. CAS No. 188627-80-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0686. | |
| Eptinezumab | Eptinezumab is a humanized monoclonal antibody. Eptinezumab binds to calcitonin gene-related peptide (CGRP) and blocks its interaction with the receptor. Eptinezumab is used for the prevention of migraine in adults [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1644539-04-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99017. | |
| EPZ004777 | EPZ004777 is a potent, selective DOT1L inhibitor with an IC50 of 0.4 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1338466-77-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15227. | |
| EPZ005687 | EPZ005687 is a potent and selective inhibitor of EZH2 with Ki of 24 nM, and has 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases. Uses: Scientific research. Group: Signaling pathways. CAS No. 1396772-26-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15555. | |
| EPZ011989 | EPZ011989 is a potent and orally active Zeste Homolog 2 (EZH2) inhibitor with metabolic stability. EPZ011989 has inhibitory inhibition for EZH2 with a Ki value of <3 nM. EPZ011989 shows robust methyl mark inhibition and anti-tumor activity. EPZ011989 can be used for the research of various cancers[1]. EPZ011989 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1598383-40-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16986. | |
| EPZ015666 | EPZ015666 (GSK3235025) is an orally available inhibitor of PRMT5 with an IC50 of 22 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK3235025. CAS No. 1616391-65-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12727. | |
| EPZ020411 | EPZ020411 is a selective inhibitor of PRMT6 with an IC50 of 10 nM, has >10 folds selectivity for PRMT6 over PRMT1 and PRMT8. EPZ020411 can be used for the research of cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1700663-41-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12970. | |
| EPZ-719 | EPZ-719 is a selective, orally effective SETD2 inhibitor with an IC50 value of 0.005 ?M. EPZ-719 has anticancer activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2697176-16-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139626. | |
| Equilenin | Equilenin is a B-ring unsaturated estrogen and one of the main ingredients in Premarin, a drug commonly used in estrogen replacement therapy. Equilenin can bind to estrogen receptors in the body and exert effects similar to endogenous estrogen. Equilenin can be used in estrogen replacement therapy and breast cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 517-09-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-116865. | |
| Equilin | Equilin (7-Dehydroestrone) is an important member of the large group of oestrogenic substances and is chemically related to menformon (oestrone). Equilin increases the growth of cortical neurons via an NMDA receptor-dependent mechanism [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 7-Dehydroestrone. CAS No. 474-86-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1176. | |
| (±)-Equol | (±)-Equol is the racemate of equol. (±)-equol exhibits EC 50 s of 200 and 74 nM for human ERα and ERβ, respectively. Equol is a metabolite of the soy isoflavones, daidzin and daidzein. Uses: Scientific research. Group: Natural products. CAS No. 94105-90-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100583A. | |
| ER-000444793 | ER-000444793 is a potent inhibitor of mitochondrial permeability transition pore (mPTP) opening. ER-000444793 inhibits mPTP with an IC50 of 2.8 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 792957-74-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100852. | |
| ER-27319 | ER-27319, an acridone derivative, is a potent and selective SYK inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC 50 of 10 μM and can be used for study in allergic diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 201010-95-9. Pack Sizes: 5 mg. Product ID: HY-138961. | |
| ER-27319 maleate | ER-27319 (maleate), an acridone derivative, is a potent and selective SKY inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 (maleate) inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC 50 of 10 μM and can be used for study in allergic diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1204480-26-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108489. | |
| Eragidomide | Eragidomide (CC-90009) is a first-in-class GSPT1-selective cereblon (CRBN) E3 ligase modulator, acts as a molecular glue. Eragidomide coopts the CRL4CRBN to selectively target GSPT1 for ubiquitination and proteasomal degradation[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-90009. CAS No. 1860875-51-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-130800. | |
| Erastin | Erastin is a ferroptosis inducer. Erastin exhibits the mechanism of ferroptosis induction related to ROS and iron-dependent signaling. Erastin inhibits voltage-dependent anion channels (VDAC2/VDAC3) and accelerates oxidation, leading to the accumulation of endogenous reactive oxygen species. Erastin also disrupts mitochondrial permeability transition pore (mPTP) with anti-tumor activity. Furthermore, Erastin can block the uptake of cystine mediated by SLC7A11 and also spares UMRC6-EV and -C91A cells from disulfidptosis under glucose starvation[1][2][3][4][5][6][7][8][9][10][11][12][13][14]. Uses: Scientific research. Group: Signaling pathways. CAS No. 571203-78-6. Pack Sizes: 1 mg; 1 mg * 5; 1 mg * 10. Product ID: HY-15763. | |
| Erastin2 | Erastin2, an Erastin (HY-15763) analog, is a ferroptosis inducer and a potent, selective inhibitor of the system xc(-) cystine/glutamate transporter[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1695533-44-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139087. | |
| Eravacycline dihydrochloride | Eravacycline dihydrochloride (TP-434 dihydrochloride) is a potent and broad-spectrum antibacterial agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TP-434 dihydrochloride; TP-434-046. CAS No. 1334714-66-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16980A. | |
| ERBB agonist-1 | ERBB agonist-1 (Compound EF-1) is an agonist for ERBB4, that activates the ERBB4 signaling pathway by inducing dimerization of the ERBB4 receptor with an EC50 of 10.5 ?M. ERBB agonist-1 induces phosphorylation of Akt and ERK1/2, reduces the collagen expression in cardiac fibroblasts, inhibits H2O2-induced cardiomyocyte death and Ang II (HY-13948)-induced cardiomyocyte hypertrophy. ERBB agonist-1 prevents fibrosis and exhibits cardioprotective efficacy in mouse models[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 930856-19-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-168438. | |
| Ercalcidiol-d3 | Ercalcidiol-d 3 is the deuterium labeled Ercalcidiol. Ercalcidiol is a metabolite of Vitamins D2. Ercalcidiol can be used as an indicator of vitamins D status [1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: 25-Hydroxy Vitamin D2-d3. CAS No. 1217467-39-4. Pack Sizes: 500 μg; 1 mg. Product ID: HY-32349S. | |
| ERD-308 | ERD-308 is a potent estrogen receptor (ER) PROTAC degrader. ERD-308 has DC50 values of 0.17 nM and 0.43 nM in MCF-7 and T47D ER+ cells. ERD-308 can inhibit the proliferation of breast cancer cells and exhibits anti-tumor activity. (Pink: Target Protein Ligand (HY-48027); Black: Linker (HY-172643); Blue: VHL Ligand (HY-112078); VHL Ligand+Linker?(HY-172645))[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2320561-35-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128600. | |
| Erdafitinib | Erdafitinib (JNJ-42756493) is a potent and orally available FGFR family inhibitor; inhibits FGFR1/2/3/4 with IC 50 s of 1.2, 2.5, 3.0 and 5.7 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-42756493. CAS No. 1346242-81-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18708. | |
| Erdosteine | Erdosteine inhibits lipopolysaccharide (LPS)-induced NF-κB activation [1] [2]. Erdosteine has muco-modulatory, anti-bacterial, anti-inflammatory and anti-oxidant effects [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RV 144. CAS No. 84611-23-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0289. | |
| Eremomycin | Eremomycin (MM 45289) is a potent glycopeptide antibiotic closely related to Vancomycin (HY-B0671). Eremomycin shows antibacterial activity in Staphylococcus spp. and Bacillus subtilis ATCC6633 , with the MIC values of 0.03-1.6 μg/mL [1]. Uses: Scientific research. Group: Natural products. Alternative Names: MM 45289; A 82846A. CAS No. 110865-90-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-105282. | |
| Erenapurstat | Erenapursta (E3330) is a direct, orally active and selective inhibitor of Ape-1 (apurinic/apyrimidinic endonuclease 1)/Ref-1 (redox factor-1) redox. Erenapursta is able to impair tumor growth and blocks the activity of NF-?B, AP-1, and HIF-1? in pancreatic cancer. Erenapursta shows anticancer activities[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E3330; APX-3330. CAS No. 136164-66-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19357. | |
| Erenumab | Erenumab is a fully human monoclonal antibody. Erenumab inhibits the calcitonin gene - related peptide ( CGRP ) receptor. Erenumab can be used for the prevention of episodic migraine [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1582205-90-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9938. | |
| ERGi-USU-6 mesylate | ERGi-USU-6 (mesylate) is an ERGi-USU-6 salt derivative that is a new selective inhibitor of ERG positive prostate cancer ( IC 50 = 0.089 μM). Uses: Scientific research. Group: Signaling pathways. CAS No. 2756327-67-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139893. | |
| Ergosta-4,6,8(14),22-tetraen-3-one | Ergosta-4,6,8(14),22-tetraen-3-one (compound 2) is a ergosteroid is isolated from the fruiting bodies of ganoderma applanatum [1]. Uses: Scientific research. Group: Natural products. CAS No. 19254-69-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3842. | |
| Ergosterol | Ergosterol is the primary sterol found in fungi, with antioxidative, anti-proliferative, and anti-inflammatory effects. Uses: Scientific research. Group: Natural products. CAS No. 57-87-4. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0181. | |
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