MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Ginsenoside Rk1 | Ginsenoside Rk1 is a unique component created by processing the ginseng plant (mainly Sung Ginseng, SG) at high temperatures [1]. Ginsenoside Rk1 has anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB [2]. Ginsenoside Rk1 has anti-tumor effect, antiplatelet aggregation activities, anti-insulin resistance, nephroprotective effect, antimicrobial effect, cognitive function enhancement, lipid accumulation reduction and prevents osteoporosis [1]. Ginsenoside Rk1 induces cell apoptosis by triggering intracellular reactive oxygen species ( ROS ) generation and blocking PI3K/Akt pathway [3]. Uses: Scientific research. Group: Natural products. CAS No. 494753-69-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N2515. |  |
| GIP, human | GIP, human, a peptide hormone consisting of 42 amino acids, is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP, human acts as an incretin hormone released from intestinal K cells in response to nutrient ingestion [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Gastric Inhibitory Peptide (GIP), human. CAS No. 100040-31-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0276. | |
| GIP (mouse) | GIP (mouse) is a gastrointestinal hormone that is expressed in and secreted from the pancreatic islets and promotes insulin secretion [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Gastric inhibitory polypeptide(mouse); GIP(1-42) (mouse). CAS No. 181591-59-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10735. | |
| Giredestrant | Giredestrant (GDC-9545), a non-steroidal estrogen receptor (ER) ligand, is an orally active and selective ER antagonist. Giredestrant potently competes with Estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-9545; RG6171. CAS No. 1953133-47-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109176. | |
| Girentuximab | Girentuximab (G250) is a chimeric monoclonal antibody that binds carbonic anhydrase IX (CAIX) , a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: G250; cG250. CAS No. 916138-87-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99023. | |
| Gisadenafil besylate | Gisadenafil besylate (UK 369003-26) is a specific, orally active phosphodiesterase 5 (PDE5) inhibitor with an IC 50 of 3.6 nM and prevents degradation of cyclic guanosine monophosphate (cGMP) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK 369003-26. CAS No. 334827-98-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108619. | |
| Gitoxin | Gitoxin, a Na + /K + -ATPase inhibitor, usually appears as a result of metabolic degradation of Digitoxin, is just the hydroxyl (ZOH) group close to the C-17β position, which changes the pharmacokinetics and pharmacodynamics of these substances considerably [1]. Uses: Scientific research. Group: Natural products. CAS No. 4562-36-1. Pack Sizes: 5 mg. Product ID: HY-136933. | |
| Givinostat | Givinostat (ITF-2357) is a HDAC inhibitor with an IC 50 of 198 and 157 nM for HDAC1 and HDAC3 , respectively. Givinostat can be used for Duchenne muscular dystrophy (DMD) research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ITF-2357. CAS No. 497833-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14842. | |
| Givinostat hydrochloride | Givinostat (ITF-2357) hydrochloride is a HDAC inhibitor with an IC 50 of 198 and 157 nM for HDAC1 and HDAC3 , respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ITF-2357 hydrochloride. CAS No. 199657-29-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14842A. | |
| Givinostat hydrochloride monohydrate | Givinostat hydrochloride monohydrate (ITF-2357 hydrochloride monohydrate) is a HDAC inhibitor with an IC 50 of 198 and 157 nM for HDAC1 and HDAC3 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ITF-2357 hydrochloride monohydrate. CAS No. 732302-99-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14842B. | |
| GL0388 | GL0388 is a Bax activator that results in Bax insertion into mitochondrial membrane. GL0388 shows antiproliferative activities against various cancer cells, with IC 50 s of 0.299-1.57 μM. GL0388 activates Bax and induce Bax-mediated apoptosis. GL0388 suppresses breast cancer xenograft tumor growth in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2886772-68-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132173. | |
| GL3 | GL3, the major component of O. fragrans seeds, is a derivative based on both phenylethanoid and methyloleoside [1]. Uses: Scientific research. Group: Natural products. CAS No. 60037-39-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N6873. | |
| Glabridin | Glabridin is a natural isoflavan from Glycyrrhiza glabra L. , binds to and activates PPARγ , with an EC 50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 59870-68-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0393. | |
| Glafenine | Glafenine is a non-steroidal anti-inflammatory drug (NSAID) that can be used for pain relief research. Glafenine can also antagonize the misfolding of SLC4A11 protein [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glafenin. CAS No. 3820-67-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-B1153. | |
| Glafenine hydrochloride | Glafenine hydrochloride is a non-narcotic analgesic and non-steroidal anti-inflammatory drug. It is an ABCG2 inhibitor with an IC 50 of 3.2 μM. Glafenine can also antagonize the misfolding of SLC4A11 protein [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glafenin hydrochloride. CAS No. 65513-72-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1153A. | |
| Glasdegib | Glasdegib (PF-04449913) is a potent and orally bioavailable smoothened inhibitor. Glasdegib (PF-04449913) binds to human SMO (amino acids 181-787) with an IC 50 of 4 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-04449913. CAS No. 1095173-27-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16391. | |
| Glatiramer acetate | Glatiramer acetate, a synthetic analogue of myelin basic protein and an immunomodulating agent, inhibits Experimental autoimmune encephalomyelitis (EAE), and can be used for the research of multiple sclerosis. Glatiramer acetate exhibits strong and promiscuous binding to MHC molecules and consequent competition with various myelin antigens for their presentation to T cells. A further aspect of its action is potent induction of specific suppressor cells of the T helper 2 (Th2) type that migrate to the brain and lead to in situ bystander suppression [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147245-92-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109520. | |
| Glaucine | Glaucine (O,O-Dimethylisoboldine) is an alkaloid extracted from Glaucium flavum that possesses various activities, including cough relief, bronchodilation, anti-inflammatory effects, analgesia, antipyretic properties, and anticancer effects. Glaucine acts as a selective and orally active inhibitor of phosphodiesterase 4 ( PDE4 ), with a K i of 3.4 μM in human bronchial tissues and polymorphonuclear leukocytes. Glaucine induces relaxation of human isolated bronchi by antagonizing calcium channels. Additionally, Glaucine inhibits the activation of NF-κB , leading to a reduction in the expression of the MMP-9 gene, thereby suppressing the migration and invasion of breast cancer cells. Therefore, Glaucine holds potential for research in asthma and breast cancer [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: O,O-Dimethylisoboldine; S-(+)-Glaucine; NSC 34396. CAS No. 475-81-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N3945. | |
| Glaucocalyxin A | Glaucocalyxin A, an ent-kauranoid diterpene from Rabdosia japonica var., induces apoptosis in osteosarcoma by inhibiting nuclear translocation of Five-zinc finger Glis 1 (GLI1) via regulating PI3K/Akt signaling pathway. Glaucocalyxin A has antitumor effect [1]. Uses: Scientific research. Group: Natural products. CAS No. 79498-31-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N2112. | |
| Glecaprevir | Glecaprevir is a novel HCV NS3/4A protease inhibitor, with IC 50 values ranging from 3.5 to 11.3 nM. Glecaprevir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 4.09 μM [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-493. CAS No. 1365970-03-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17634. | |
| Glecirasib | Glecirasib (Compound 1-2; JAB-21822) is an orally active and potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. Glecirasib has the potential for the research of KRAS G12C-mediated cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JAB-21822; KRAS G12C inhibitor 36. CAS No. 2657613-87-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-143589. | |
| Glembatumumab | Glembatumumab is a fully human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be coupled to the microtubule inhibitor monomethyl auristatin E to form glembatumumab vedotin. Glembatumumab vedotin is an antibody-agent coupling ( ADC ) with antitumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1020264-78-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99205. | |
| Glembatumumab vedotin | Glembatumumab vedotin (CDX-011) is an ADC ( antibody-drug conjugates (ADCs) ) comprising a fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB) and conjugated to the potent tubulinbinding cytotoxic agent MMAE via a protease-sensitive vc linker. Glembatumumab vedotin has potent anticancer effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDX-011; CR011-vcMMAE. CAS No. 1182215-65-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141604. | |
| Glesatinib hydrochloride | Glesatinib hydrochloride (MGCD265 hydrochloride) is an orally active, potent MET/SMO dual inhibitor. Glesatinib hydrochloride, a tyrosine kinase inhibitor, antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGCD265 hydrochloride. CAS No. 1123838-51-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19642A. | |
| Gliadin p31-43 | Gliadin p31-43 is an undigested gliadin peptide. Gliadin p31-43 induces an innate immune response in the intestine and interferes with endocytic trafficking. Gliadin p31-43 can be used for celiac disease research [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 176326-01-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P3151. | |
| Gliadins | Gliadins (Tyrosyl prolyl glutaminyl prolyl glutamine) comprise a family of glutamine- and proline-rich monomeric proteins that plays an role in autoimmune disease, such as celiac disease [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Tyrosyl prolyl glutaminyl prolyl glutamine. CAS No. 9007-90-3. Pack Sizes: 100 mg. Product ID: HY-W355779. | |
| Glibenclamide | Glibenclamide (Glyburide) is an orally active ATP-sensitive K + channel ( K ATP ) inhibitor and can be used for the research of diabetes and obesity [1]. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of K ATP and inhibits the cystic fibrosis transmembrane conductance regulator protein ( CFTR ) [3]. Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability [4]. Glibenclamide can induce autophagy [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glyburide. CAS No. 10238-21-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15206. | |
| Glibornuride | Glibornuride is a blocker of ATP-sensitive K + channels ( K ATP channel ) with a pK i of 5.75 [1]. Antidiabetic agent [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 26944-48-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17451. | |
| Gliclazide | Gliclazide (S1702) is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC 50 of 184 nM. Gliclazide is used as an antidiabetic [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S1702; SE1702. CAS No. 21187-98-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B0753. | |
| Glimepiride | Glimepiride (Glimperide) is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED 50 of 182 μg/kg. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glimperide; HOE-490. CAS No. 93479-97-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0104. | |
| Glimepiride (Standard) | Glimepiride (Standard) is the analytical standard of Glimepiride. This product is intended for research and analytical applications. Glimepiride (Glimperide) is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg. Uses: Scientific research. Group: Signaling pathways. CAS No. 93479-97-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0104R. | |
| Gliotoxin | Gliotoxin is a secondary metabolite, the most abundant mycotoxin secreted by A. fumigatus , inhibits the phagocytosis of macrophages and the immune functions of other immune cells [1]. Gliotoxin inhibits inducible NF-κB activity by preventing IκB degradation, which consequently induces host-cell apoptosis [2]. Gliotoxin activates PKA and increases intracellular cAMP concentration; modulates actin cytoskeleton rearrangement to facilitate A. fumigatus internalization into lung epithelial cells [3]. Gliotoxin is a potent NOTCH2 transactivation inhibitor, can effectively induce apoptosis of chronic lymphocytic leukemia (CLL) cells [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Aspergillin. CAS No. 67-99-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6727. | |
| Glipizide | Glipizide (CP 2872; K 4024) a potent, orally active and sulfonylurea class anti-diabetic agent and can be used for type 2 diabetes mellitus research but not type 1. Glipizide acts by partially blocking ATP-sensitive potassium ( K ATP ) channels among β cells of pancreatic islets of Langerhans [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 28720; K 4024. CAS No. 29094-61-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0254. | |
| Glipizide (Standard) | Glipizide (Standard) is the analytical standard of Glipizide. This product is intended for research and analytical applications. Glipizide (CP 2872; K 4024) a potent, orally active and sulfonylurea class anti-diabetic agent and can be used for type 2 diabetes mellitus research but not type 1. Glipizide acts by partially blocking ATP-sensitive potassium ( K ATP ) channels among β cells of pancreatic islets of Langerhans [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 29094-61-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0254R. | |
| Gliquidone | Gliquidone (AR-DF 26) is an anti-diabetic agent in the sulfonylurea class, used in the treatment of diabetes mellitus type 2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AR-DF 26. CAS No. 33342-05-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1114. | |
| Glisoxepide | Glisoxepide, a sulphonamide derivative, is an orally available nonselective K(ATP) channel blocker, with antihyperglycemic activity and cardiovascular regulation effect [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 25046-79-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-A0176. | |
| Globotriaosylsphingosine | Globotriaosylsphingosine (lyso-Gb3) inhibits the growth of fibroblasts, as well as their differentiation into myofibroblasts, and collagen expression. Globotriaosylsphingosine can be used for Fabry disease research [1]. Uses: Scientific research. Group: Natural products. Alternative Names: lyso-Gb3. CAS No. 126550-86-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N12408. | |
| Glofitamab | Glofitamab (RO7082859) is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells. Glofitamab leads to T-cell activation, proliferation, and tumor cell killing upon binding to CD20 on malignant cells. Glofitamab induces durable complete remissions in relapsed or refractory B-Cell non-Hodgkin lymphoma (B-NHL) [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RO7082859. CAS No. 2229047-91-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99024. | |
| GLP-1(32-36)amide | GLP-1(32-36)amide, a pentapeptide, derived from the C terminus of the glucoregulatory hormone GLP-1. GLP-1(32-36)amide could inhibit weight gain and modulate whole body glucose metabolism in diabetic mice [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1417302-71-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3102. | |
| GLP-1(7-36), amide | GLP-1(7-36), amide is a physiological incretin hormone that stimulates insulin secretion. Uses: Scientific research. Group: Peptides. Alternative Names: Glucagon-like peptide-1 (GLP-1)(7-36), amide; Human GLP-1 (7-36), amide. CAS No. 107444-51-9. Pack Sizes: 1 mg. Product ID: HY-P0054A. | |
| GLP-1(7-36), amide acetate | GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells. Uses: Scientific research. Group: Peptides. Alternative Names: Glucagon-like peptide-1 (GLP-1)(7-36), amide acetate; Human GLP-1 (7-36), amide acetate. CAS No. 1119517-19-9. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P0054. | |
| GLP-1(7-37) | GLP-1(7-37) is an intestinal insulinotropic hormone that augments glucose induced insulin secretion. Uses: Scientific research. Group: Peptides. CAS No. 106612-94-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0055. | |
| GLP-1(7-37) acetate | GLP-1(7-37) acetate is an intestinal insulinotropic hormone that augments glucose induced insulin secretion [1]. Uses: Scientific research. Group: Peptides. CAS No. 1450806-98-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0055A. | |
| GLP-1(9-36)amide | GLP-1(9-36)amide is a major metabolite of glucagon-like peptide-1-(7-36) amide formed by the enzyme dipeptidyl peptidase-4 (DPP-4). GLP-1(9-36)amide acts as an antagonist to the human pancreatic GLP-1 receptor [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 161748-29-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1141. | |
| GLP-1R agonist 4 | GLP-1R agonist 4 is a potent agonist of GLP-1R. Glucagon-like peptide-1 (GLP-1) is an intestinal hypoglycemic hormone secreted by L-cells in the lower gastrointestinal tract. GLP-1R agonist 4 has the potential for the research of diabetes (extracted from patent WO2019239319A1, compound 96) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2401894-26-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-144035. | |
| GLP-1 receptor agonist 10 | GLP-1 receptor agonist 10 (compound 42) is an agonist of GLP Receptor. GLP-1 receptor agonist 10 inhibits food intake and reduces glucose excursion in mice. GLP-1 receptor agonist 10 can be used in the study of type 2 diabetes (T2DM) and obesity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3015555-46-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153798. | |
| GLP-1 receptor agonist 12 | GLP-1 receptor agonist 12 (compound 20A) is an agonist of GLP Receptor. GLP-1 receptor agonist 12 can be used in the study of diseases such as diabetes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2775376-50-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-153816. | |
| GLP-1 receptor agonist 2 | GLP-1 receptor agonist 2 is a glucagon-like peptide-1 receptor (GLP-1R) agonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230197-64-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-112679. | |
| GLP-1 receptor agonist 7 | GLP-1 receptor agonist 7 is a potent agonist of glucagon-like peptide-1 ( GLP-1 ). GLP-1 receptor agonist 7 has the potential for the research of GLP-1-associated diseases, disorders, and conditions including diabetes mellitus (extracted from patent WO2021219019A1, compound 130b) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2736447-04-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-145412. | |
| GLP-2(3-33) | GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor ( EC 50 =5.8 nM) [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 275801-62-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2625. | |
| GLP-2(rat) | GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR) [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 195262-56-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1142. | |
| GLPG0634 analog | GLPG0634 analog (Compoun 176) is a broad spectrum JAK inhibitor with IC 50 values of <100 nM against JAK1, JAK2 and JAK3 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1206101-20-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13961. | |
| GLPG3667 | GLPG3667 is a reversible, ATP-competitive and orally active TYK2 inhibitor with an IC 50 of 2.3 nM. GLPG3667 inhibits IFNα/pSTAT1, and the IC 50 values ??in human peripheral blood mononuclear cell (PBMC) and whole blood assays are 70 nM and 623 nM, respectively. GLPG3667 has the potential for the study of inflammatory and autoimmune diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2308520-97-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156961. | |
| GLS1 Inhibitor-1 | GLS1 Inhibitor-1 (Compound 27) is an orally active inhibitor for glutaminase 1 ( GLS1 ) with an IC 50 of 0.021 μM. GLS1 Inhibitor-1 inhibits the proliferation of PC-3 with an IC 50 of 0.3 nM. GLS1 Inhibitor-1 exhibits antitumor efficacy against NCI-H1703 with GI 50 of 0.011 μM. GLS1 Inhibitor-1 exhibits moderate pharmacokinetic characteristics [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1832646-52-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136704. | |
| [Glu1]-Fibrinopeptide B | [Glu1]-Fibrinopeptide B is derived from fibrinopeptide B amino acid residues 1-14. Human fibrinopeptide B (hFpB), a thrombin-derived proteolytic cleavage product of the fibrinogen B beta-chain, to stimulate neutrophils (PMN), monocytes, and fibroblasts. Uses: Scientific research. Group: Peptides. CAS No. 103213-49-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0308. | |
| Glucagon (1-29), bovine, human | Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis [1]. Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Glucagon. CAS No. 16941-32-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P0082. | |
| Glucagon (1-29), bovine, human hydrochloride | Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. Glucagon hydrochloride stimulates gluconeogenesis [1]. Glucagon (1-29), bovine, human, porcine hydrochloride activates HNF4α and increases HNF4α phosphorylation [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Glucagon hydrochloride. CAS No. 28270-04-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0082A. | |
| Glucagon receptor antagonist-2 | Glucagon receptor antagonist-2 is a highly potent glucagon receptor antagonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 202917-18-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-50158. | |
| Glucobrassicin potassium | Glucobrassicin potassium is a glucosinolate (GSL) isolated from wild carrot ( Raphanus raphanistrum L.). Glucobrassicin can be used in biological fumigation or allelopathy research for weed management [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 143231-38-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7659A. | |
| Glucocorticoid receptor agonist | Glucocorticoid receptor agonist is a Glucocorticoid receptor agonist that acts on Glucocorticoid receptor ( GR ), progesterone receptor ( PR ) and mineralocorticoid receptor ( MR ) with the IC 50 values of 2.1 , 1200 and 210 nM, respectively. Glucocorticoid receptor agonist has steroid-like anti-inflammatory properties and may be used to improve metabolism and reduce increased levels of body fat and serum insulin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1245526-82-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14234. | |
| Glucocorticoid receptor agonist-1 | Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC 50 of 2.8 nM extracted from patent WO2017210471A1, compound 41 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2166375-82-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131974. | |
| Glucocorticoid receptor agonist-2 | Glucocorticoid receptor agonist-2 (compound 21) is an glucocorticoid receptor agonist with an IC 50 value of 6.6 nM. Glucocorticoid receptor agonist-2 can be used to synthesize anti-inflammatory ADC molecules. Glucocorticoid receptor agonist-2 is an active reference of ABBV-3373 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2166378-92-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148435. | |
| Glucocorticoid receptor agonist-3 | Glucocorticoid receptor agonist-3 (Preparation 6) is a glucocorticoid receptor agonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2842165-73-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-160177. | |
| Glucocorticoid receptor drug-linke 1 | Glucocorticoid receptor drug-linke 1 is a drug-linker conjugate, that can be used for synthesis of BDCA2-targeting ADC [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3048601-02-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-170587. | |
| Glucoerucin potassium | Glucoerucin potassium is an aryl hydrocarbon receptor antagonist and is the 4-methylthio-butyl glucosinolate found in the seeds of Eruca sativa Mill [1]. Uses: Scientific research. Group: Natural products. CAS No. 15592-37-7. Pack Sizes: 1 mg. Product ID: HY-N8445. | |
| Glucokinase | Glucokinase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 9001-36-9. Pack Sizes: 100 U; 500 U; 1 KU. Product ID: HY-P2761. | |
| Gluconate Calcium | Gluconate Calcium (Calcium D-gluconate) is a mineral supplement, manufactured by the neutralization of gluconic acid with lime or calcium carbonate. Uses: Scientific research. Group: Natural products. Alternative Names: Calcium D-gluconate; Gluconic acid hemicalcium salt. CAS No. 299-28-5. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-B1092. | |
| Gluconate sodium | Gluconate sodium (D-Gluconic acid sodium salt) is a corrosion and scale inhibitor. Uses: Scientific research. Group: Natural products. Alternative Names: D-Gluconic acid sodium salt; Sodium D-gluconate; D-Gluconate sodium salt. CAS No. 527-07-1. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-B1092A. | |
| Glucoraphanin | Glucoraphanin, a natural glucosinolate found in cruciferous vegetable, is a stable precursor of the Nrf2 inducer sulforaphane, which possesses antioxidant, anti-inflammatory, and anti-carcinogenic effects. Uses: Scientific research. Group: Natural products. CAS No. 21414-41-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N4068. | |
| Glucoraphanin (Standard) | Glucoraphanin (Standard) is the analytical standard of Glucoraphanin. This product is intended for research and analytical applications. Glucoraphanin, a natural glucosinolate found in cruciferous vegetable, is a stable precursor of the Nrf2 inducer sulforaphane, which possesses antioxidant, anti-inflammatory, and anti-carcinogenic effects. Uses: Scientific research. Group: Natural products. CAS No. 21414-41-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N4068R. | |
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