MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Eact | Eact is a selective and potent activator of TMEM16A , directly activates the TRPV1 channels in sensory nociceptors and produces itch, acute nociception and thermal hypersensitivity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 461000-66-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103368. |  |
| (E)-AG 556 | (E)-AG 556 is a highly selective EGFR inhibitor and also blocks LPS-induced TNF-α production [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E)-Tyrphostin AG 556. CAS No. 133550-41-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101041. | |
| EB1 | EB1 is the inhibitor of kinases MNK with IC 50 s of 0.69 μM (MNK1) and 9.4 μM (MNK2). EB1 selectively inhibits the growth of cancer cells, but not normal cells. EB1 also increases cell apoptosis and suppresses eIF4E phosphorylation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 42951-68-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146805. | |
| EB1002 | EB1002 is a selective NK2R agonist. EB1002 significantly raises the expression levels of mitochondrial biosynthesis-related genes (like PGC-1?) in obese mice, indicating that it promotes energy expenditure by boosting mitochondrial activity. EB1002 also increases the insulin sensitivity and improves glycolipid metabolism of the mice. EB1002 is promising for research of obesity and type 2 diabetes[1]. Uses: Scientific research. Group: Peptides. CAS No. 2770688-48-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10746. | |
| Ebastine | Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LAS-W 090; RP64305. CAS No. 90729-43-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0674. | |
| Ebdarokimab | Ebdarokimab (AK101) is a humanized IgG1-κ antibody, usually expressed in CHO (Chinese Hamster Ovary) cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2393651-11-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99869. | |
| Ebeiedinone | Ebeiedinone, a steroidal alkaloid from Fritillaria species, inhibits the bioactivity of human whole blood cholinesterase ( ChE ) at the concentration of 0.1 mM, with the inhibitory effects of 69.0% [1]. Uses: Scientific research. Group: Natural products. CAS No. 25650-68-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107275. | |
| Eberconazole nitrate | Eberconazole nitrate is a dichlorinated imidazole derivative with antifungal activity. Eberconazole nitrate is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole nitrate has potential for the study of dermatophytosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130104-32-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106542A. | |
| (E)-β-Farnesene | (E)-β-Farnesene (trans-β-Farnesene) is an aphid alarm pheromone, which can be found in Phlomis aurea Decne essential oil. (E)-β-Farnesene shows good binding score with a value of -30.64 kcal/mol to the CDK2 receptor. (E)-β-Farnesene also exhibits good affinity to odorant-binding protein 3 ( OBP3 ). (E)-β-Farnesene can be used as a feeding stimulant for the sand fly Lutzomyia longipalpis [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: trans-β-Farnesene. CAS No. 18794-84-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-N7364. | |
| (E)-β-Ionone | (E)-β-Ionone is the isomer of β-Ionone (HY-W015084). β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. β-Ionone has anti-cancer activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: β-Lonone. CAS No. 79-77-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W015084A. | |
| Eblasakimab | Eblasakimab (ASLAN004; CSL-334) is a human IgG4 antibody that specifically targets IL13RA1 and is primarily expressed by CHO-K1 cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ASLAN004; CSL-334; MK-6105. CAS No. 2445460-16-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99870. | |
| EBP-IN-1 | EBP-IN-1 (compound 11) is an inhibitor of emopamil-binding protein (EBP), a sterol isomerase in the cholesterol biosynthetic pathway. EBP-IN-1 has a long half-life in rodents and has good metabolic turnover and brain penetration properties. EBP-IN-1 enhances oligodendrocyte formation in human cortical organoids[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162351. | |
| Ebrotidine | Ebrotidine(FI 3542) is a competitive H2-receptor antagonist (Ki= 127. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FI3542. CAS No. 100981-43-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15538. | |
| Ebselen | Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker [1] [2]. Ebselen potently inhibits M pro ( IC 50 =0.67 μM) and COVID-19 virus ( EC 50 =4.67 μM) [3].Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SPI-1005; PZ-51; CCG-39161. CAS No. 60940-34-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13750. | |
| Ebvaciclib | PF-06873600 is a selective and orally bioavailable inhibitor of cyclin-dependent kinase (CDK), with Ki values of 0.09 nM, 0.13 nM and 0.16 nM for CDK2, CDK4 and CDK6, respectively. PF-06873600 has potential antineoplastic activity[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-06873600. CAS No. 2185857-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114177. | |
| EC-17 disodium salt | EC-17 disodium salt is a folate receptor alpha (FR?) targeting contrast agent with fluorescent properties in the visible light spectrum. The EC-17 maximum excitation and emission wavelengths are 490 nm and 520 nm, respectively[1][2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 910661-33-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13615A. | |
| EC19 | EC19 is an analogue of 13-cis retinoic acid (HY-15127). EC19 shows embryo toxicity. EC19 causes mild effects on upper beak outgrowth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1010694-08-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110296. | |
| EC23 | EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGN 190205; BASF-46928. CAS No. 104561-41-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12309. | |
| EC330 | EC330 is a leukemia inhibitory factor ( LIF ) inhibitor. EC330 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2016795-77-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100949. | |
| EC359 | EC359 is a potent, selective, high affinity and orally active leukemia inhibitory factor receptor (LIFR) inhibitor with a Kd of 10.2 nM, which directly interacts with LIFR to effectively block LIF/LIFR interactions[1]. EC359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2012591-09-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120142. | |
| EC5026 | EC5026 (BPN-19186) is a first-in-class, non-opioid and orally active soluble Epoxide Hydrolase (sEH) inhibitor. EC5026 shows efficacy for inflammatory and neuropathic pain[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BPN-19186. CAS No. 1809885-32-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135653. | |
| Ecabet sodium | Ecabet sodium (TA-2711) is currently applied to some gastrointestinal disease by inhibiting the ROS production and improving Helicobacter pylori eradication [1]. Ecabet sodium reduces apoptosis [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TA-2711. CAS No. 86408-72-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0691A. | |
| E-Cadherin activator-1 | E-cadherin activator-1 (Compound 13m) is an E-Cadherin activator. E-cadherin activator-1 can be used in the study of colorectal carcinoma [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 912787-60-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-164712. | |
| Ecamsule | Ecamsule is a broad-spectrum UVA filter that can be used in sunscreen product. Ecamsule reduces biological damage caused by solar radiation such as pyrimidine dimer formation, p53 protein accumula-tion, or collagenase 2 expression. Ecamsule has the potential for the research of polymorphous light eruption (PMLE) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 92761-26-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16182. | |
| Ecdysone | Ecdysone (α-Ecdysone), a major steroid hormone in insects and herbs, triggers mineralocorticoid receptor (MR) activation and induces cellular apoptosis. Ecdysone plays essential roles in coordinating developmental transitions and homeostatic sleep regulation through its active metabolite 20-hydroxyecdysone (Crustecdysone; 20E; HY-N6979) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: α-Ecdysone. CAS No. 3604-87-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0179. | |
| eCF506 | eCF506 (NXP900) is a highly potent and orally active YES1/SRC kinase inhibitor with an IC50 of 0.47 nM. eCF506 locks its target into its native closed conformation, thereby inhibiting both kinase activity and complex formation with protein partners. eCF506 can be used for the study of esophageal squamous cancer and breast cancer[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NXP900. CAS No. 1914078-41-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112096. | |
| Echinacoside | Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche deserticola , effectively inhibits Wnt/β-catenin signaling. Echinacoside elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Antiosteoporotic activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 82854-37-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0020. | |
| Echinocystic acid | Echinocystic acid is a natural pentacyclic triterpene with potent antioxidant, anti-inflammatory and analgesic activities[1][2]. Uses: Scientific research. Group: Natural products. CAS No. 510-30-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0271. | |
| Ecleralimab | Ecleralimab (CSJ-117; NVP-CSJ117) is a Fab-IgG1-λ2 antibody targeting the thymic stromal lymphopoietin TSLP. The expression system of Ecleralimab is usually CHO (Chinese Hamster Ovary) cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CSJ-117; NVP-CSJ117. CAS No. 2415207-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99872. | |
| Eclitasertib | Eclitasertib (DNL-758) is a potent receptor-interacting protein kinase 1 (RIPK1) inhibitor with an IC 50 of 0.0375 μΜ [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DNL-758; SAR-443122. CAS No. 2125450-76-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114371. | |
| Ecnoglutide | Ecnoglutide (XW003) is a long-acting, cAMP-biased glucagon-like peptide 1 (GLP-1) receptor agonist. Ecnoglutide can be used for research of T2DM and obesity [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: XW003. CAS No. 2459531-73-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3366. | |
| Econazole | Econazole is an antifungal compound. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Econazol. CAS No. 27220-47-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B0885. | |
| Econazole nitrate | Econazole nitrate is an imidazole class antifungal medication [1]. Econazole nitrate also has antibacterial activity [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24169-02-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0453. | |
| Ecopipam hydrobromide | Ecopipam (SCH 39166) hydrobromide is a potent, selective and orally active antagonist of dopamine D1/D5 receptor , with K i s of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrobromide shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (K i =0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam hydrobromide can be used for the research of schizophrenia and obesity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 39166 hydrobromide. CAS No. 2587360-22-1. Pack Sizes: 1 mg. Product ID: HY-110033. | |
| Ecopipam hydrochloride | Ecopipam (SCH 39166) hydrochloride is a potent, selective and orally active antagonist of dopamine D1/D5 receptor , with K i s of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrochloride shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (K i =0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam hydrochloride can be used for the research of schizophrenia and obesity [1] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 39166 hydrochloride. CAS No. 190133-94-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14689. | |
| Ecromeximab | Ecromeximab (KM 871; KW 2871) is a mouse-derived IgG-κ chimeric antibody targeting ganglioside GD3. Ecromeximab is expressed by YB2/0 rat hybridoma cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: KM 871; KW 2871. CAS No. 292819-64-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99873. | |
| Ectoine | Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 96702-03-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-107784. | |
| Eculizumab | Eculizumab (Anti-Human C5, Humanized Antibody) is a long-acting humanized monoclonal antibody targeted against complement C5. Eculizumab inhibits the cleavage of C5 into C5a and C5b and hence inhibits deployment of the terminal complement system including the formation of membrane attack complex (MAC). Eculizumab has the potential for haemolysis research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human C5, Humanized Antibody. CAS No. 219685-50-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9914. | |
| EDANS | EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET) [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 1,5-EDANS. CAS No. 50402-56-7. Pack Sizes: 100 mg. Product ID: HY-D1080. | |
| Edaravone | Edaravone is a strong novel free radical scavenger, and inhibits MMP -9-related brain hemorrhage in rats treated with tissue plasminogen activator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCI-186. CAS No. 89-25-8. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g; 25 g. Product ID: HY-B0099. | |
| Edaravone-d5 | Edaravone-d 5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: MCI-186-d5. CAS No. 1228765-67-0. Pack Sizes: 1 mg. Product ID: HY-B0099S. | |
| Edaravone (Standard) | Edaravone (Standard) is the analytical standard of Edaravone. This product is intended for research and analytical applications. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Uses: Scientific research. Group: Signaling pathways. CAS No. 89-25-8. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B0099R. | |
| Edasalonexent | Edasalonexent (CAT-1004) is an orally bioavailable NF-κB inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CAT-1004. CAS No. 1204317-86-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17630. | |
| Edecesertib | Edecesertib (GS-5718) is a selective, potent, orally active IRAK-4 inhibitor. Edecesertib has anti-inflammatory activity. Edecesertib can be used for rheumatoid arthritis (RA) and lupus erythematosus (LE) research[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-5718. CAS No. 2408839-73-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147264. | |
| Edelfosine | Edelfosine (ET-18-OCH3) is a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 Death receptor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ET-18-OCH3. CAS No. 70641-51-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108610A. | |
| Edelinontrine | Edelinontrine (PF-04447943) is a potent inhibitor of human recombinant PDE9A (IC50=12 nM) with >78-fold selectivity, respectively, over other PDE family members (IC50>1000 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-04447943. CAS No. 1082744-20-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15441. | |
| Edicotinib | Edicotinib (JNJ-40346527) is a potent, selective, brain penetrant and orally active colony-stimulating factor-1 receptor (CSF-1R) inhibitor with an IC50 of 3.2 nM. Edicotinib exhibits less inhibitory effects on KIT and FLT3 with IC50 values of 20 nM and 190 nM, respectively[1]. Edicotinib limits microglial expansion and attenuates microglial proliferation and neurodegeneration in mice. Edicotinib has the potential for Alzheimers disease and rheumatoid arthritis research[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-40346527; JNJ-527. CAS No. 1142363-52-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109086. | |
| Edivoxetine hydrochloride | Edivoxetine (hydrochloride) is a selective and potent norepinephrine reuptake inhibitor (NERI) being used in depressive disorder or attention-deficit/hyperactivity disorder. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY 2216684 hydrochloride. CAS No. 1194374-05-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15413A. | |
| Edonerpic maleate | Edonerpic maleate is a novel neurotrophic agent which can inhibit amyloid-β peptides ( Aβ ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: T-817 maleate; T-817MA. CAS No. 519187-97-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17631A. | |
| Edotreotide | Edotreotide is a somatostatin analogue. Edotreotide bound to various radionuclides, has the potential for the research and diagnosis of certain types of cancer [1]. Edotreotide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. Alternative Names: DOTATOC; SDZ-SMT 487; SMT 487. CAS No. 204318-14-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106033. | |
| Edoxaban | Edoxaban (DU-176b) is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with K i values of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban can be used in preventing thromboembolic disease research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU-176. CAS No. 480449-70-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10264. | |
| Edoxaban-d6 | Edoxaban-d 6 is deuterium labeled Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention. Edoxaban is also a weak inhibitor of thrombin and factor IXaβ (FIXa), with Kis of 6.00 μM and 41.7 μM, respectively, exhibits >10000-fold selectivity for FXa. Edoxaban has antithrombotic properties and has potential for thromboembolic diseases treatment [1] [2] [3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: DU-176-d6. CAS No. 1304701-57-2. Pack Sizes: 500 μg; 1 mg. Product ID: HY-10264S. | |
| Edoxaban tosylate | Edoxaban (DU-176b) tosylate is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with K i s of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban tosylate exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban tosylate can be used for preventing thromboembolic disease research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU-176b. CAS No. 480449-71-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-10264A. | |
| Edoxaban tosylate monohydrate | Edoxaban (DU-176b) monohydrate is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with K i s of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban monohydrate exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban monohydrate can be used for preventing thromboembolic disease research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU-176b monohydrate. CAS No. 1229194-11-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10264B. | |
| EDP-305 | EDP-305 is an orally active, potent and selective farnesoid X receptor (FXR) agonist, with EC 50 values of 34 nM (chimeric FXR in CHO cells) and 8 nM (full-length FXR in HEK cells). EDP-305 shows a potent and consistent antifibrotic effect. EDP-305 can be used for primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH) research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1933507-63-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134988. | |
| Edpetiline | Edpetiline is a principal alkaloid from P. eduardi. Edpetiline has significant antiinflammatory effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 32685-93-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N1921. | |
| Edratide | Edratide (TV 4710) is a synthetic peptide of 19 amino acid based on the complementarity-determining region 1 (CDR1) of a human anti-DNA antibody that expresses a major idiotype denoted 16/6 Id. Edratide reduces the rates of apoptosis ( Apoptosis ) and down-regulates of caspase-8 and caspase-3, up-regulates Bcl-xL. Edratide has the potential for the research of systemic lupus erythematosus (SLE) [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: TV 4710. CAS No. 433922-67-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3560. | |
| Edrecolomab | Edrecolomab (Panorex) is a murine monoclonal antibody to the cell-surface glycoprotein 17-1A , expressed on epithelial tissues and on various carcinomas. Edrecolomab shows anti-tumor activity and can be used in colorectal carcinoma research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Panorex; CO17-1A. CAS No. 156586-89-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99231. | |
| Edrophonium chloride | Edrophonium chloride is a reversible inhibitor of acetylcholinesterase. Uses: Scientific research. Group: Signaling pathways. CAS No. 116-38-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0882. | |
| EDTA dipotassium dihydrate | EDTA dipotassium dihydrate is a metal ion chelator that forms stable and water-soluble chelates with a variety of metal ions. EDTA dipotassium is commonly used as a blood anticoagulant, which can effectively prevent blood coagulation and maintain the morphology and function of cells in blood samples. In the industrial field, EDTA dipotassium can be used to remove the adverse effects of metal ions and prevent oxidation and deterioration caused by metal ions [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ethylenediaminetetraacetic acid dipotassium dihydrate. CAS No. 25102-12-9. Pack Sizes: 50 g; 100 g. Product ID: HY-D0836. | |
| EDTA disodium | EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ethylenediaminetetraacetic acid disodium. CAS No. 139-33-3. Pack Sizes: 10 g; 25 g. Product ID: HY-W018746. | |
| EDTA iron sodium | EDTA iron sodium (NaFeEDTA; Sodium iron EDTA) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ethylenediaminetetraacetic acid iron sodium. CAS No. 15708-41-5. Pack Sizes: 10 mM * 1 mL; 100 g. Product ID: HY-131926. | |
| (E,E)-2,4-Hexadienal | (E,E)-2,4-Hexadienal is an organic compound belonging to the aldehyde class. It has a strong, pungent smell and is commonly found in a variety of foods, such as fruits and vegetables. (E,E)-2,4-Hexadienal has various applications in the food industry, especially as a flavoring agent, which helps to impart a characteristic aroma and taste to certain foods. In addition, it has potential use in inhibiting inflammatory diseases and cancer. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: trans,trans-2,4-Hexadienal. CAS No. 142-83-6. Pack Sizes: 1 mg. Product ID: HY-W068035. | |
| (E,E)-Bisdemethoxycurcumin | (E,E)-Bisdemethoxycurcumin ((E,E)-Curcumin III) is a curcumin derivative with anti-inflammatory and anticancer activities [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: (E,E)-Curcumin III; (E,E)-Didemethoxycurcumin. CAS No. 33171-05-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0007. | |
| EED226 | EED226 is a polycomb repressive complex 2 (PRC2) inhibitor, which binds to the K27me3-pocket on embryonic ectoderm development (EED) and shows strong antitumor activity in xenograft mice model[1]. EED226 is a potent, selective, and orally bioavailable EED inhibitor[2]. EED226 inhibits PRC2 with an IC50 of 23.4 nM when the H3K27me0 peptide is used as a substrate in the in vitro enzymatic assays[3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2083627-02-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101117. | |
| EEDQ | EEDQ is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: EEDQ. CAS No. 16357-59-8. Pack Sizes: 25 g. Product ID: HY-Y1191. | |
| Eeyarestatin I | Eeyarestatin I, a potent endoplasmic reticulum-associated protein degradation (ERAD) inhibitor, is a potent protein translocation inhibitor. Eeyarestatin I inhibits Sec61 translocon. Eeyarestatin I targets the p97-associated deubiquitinating process (PAD) and inhibits atx3-dependent deubiquitination. Eeyarestatin I interferes at a step prior to proteasomal degradation. Eeyarestatin I induces cell death via the proapoptotic protein NOXA and has anticancer effects[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 412960-54-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110078. | |
| EF24 | EF24, a curcumin analogue, is an NF-kB inhibitor with great anti-tumor efficacy and oral bioavailability via deactivation of the MAPK/ERK signaling pathway in oral squamous cell carcinoma (OSCC). EF24 is active against melanoma and breast cancer cell lines with GI50 values of 0.7 ?M and 0.8 ?M, respectively. EF24 induces cell cycle arrest and apoptosis in MDA-MB-231 human breast cancer cells and DU-145 human prostate cancer cells. EF24 increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 342808-40-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119272. | |
| EF-5 | EF-5 (EF5; 2-Nitroimidazole) is a hypoxia labeling agent used to identify hypoxia in cells. Uses: Scientific research. Group: Signaling pathways. CAS No. 152721-37-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00118. | |
| Efalizumab | Efalizumab is a targeted T cell modulator, and is a humanized monoclonal antibody of CD11a , the α subunit of LFA-1. Efalizumab inhibits T cell activation, cutaneous T cell trafficking, and T cell adhesion to keratinocytes, can be used for plaque psoriasis research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 214745-43-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9947. | |
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