MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| FR122047 | FR122047 (hydrochloride) is a selective and oral active inhibitor of COX-1 with an IC 50 of 28 nM. FR122047 hydrochloride has antiplatelet, analgesic and anti-inflammatory effects in vivo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130717-51-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103386. |  |
| FR 180204 | FR 180204 is an ATP-competitive and selective ERK inhibitor. FR 180204 inhibits ERK1 and ERK2 with IC 50 s of 0.51 μM ( K i =0.31 μM) and 0.33 μM ( K i =0.14 μM), respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 865362-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12275. | |
| Framycetin | Framycetin (Neomycin B), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a K i of 35 μM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a K i of 13.5 μM. Framycetin, a 5"-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Neomycin B; Fradiomycin B. CAS No. 119-04-0. Pack Sizes: 25 mg (16.27 mM * 2.5 mL in 0.9% NaCl); 50 mg (16.27 mM * 5 mL in 0.9% NaCl); 100 mg (16.27 mM * 10 mL in 0.9% NaCl). Product ID: HY-17624. | |
| Framycetin sulfate | Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a K i of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a K i of 13.5 μM. Framycetin sulfate, a 5"-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Neomycin B sulfate; Fradiomycin B sulfate. CAS No. 4146-30-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-17624A. | |
| Fraxetin | Fraxetin is isolated from Fraxinus rhynchophylla Hance and has oral bioactivity. Fraxetin has anti-tumor, antibacterial, antioxidant, and anti-inflammatory effects. Fraxetin can induce cell apoptosis [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 574-84-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0580. | |
| Fremanezumab | Fremanezumab (TEV-48125) is a humanized IgG2a monoclonal antibody that selectively and potently binds to calcitonin gene-related peptide (CGRP). CGRP is a 37-amino acid neuropeptide involved in central and peripheral pathophysiological events of migraine. Fremanezumab has the potential for chronic migraine research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TEV-48125. CAS No. 1655501-53-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99019. | |
| Fresolimumab | Fresolimumab (GC1008) is a human monoclonal antibody against TGF-β that neutralizes all mammalian active subtypes of TGF-&beta. The binding affinity of Fresolimumab to TGF-β2 is 1.8 nM. Fresolimumab radiolabeled with 89 Zr can be used for PET analysis of TGF-β expression, antibody uptake and organ distribution. Fresolimumab can be used in the study of cancer, osteogenesis imperfecta, fibrosis and kidney disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GC1008. CAS No. 948564-73-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99020. | |
| Frexalimab | Frexalimab (SAR441344) is a second-generation monoclonal antibody targeting the CD40 ligand (CD40L) with a good safety profile. Frexalimab inhibits the binding between CD40 and CD40L to modulate immune response. Frexalimab is likely to help prevent the process of β-cell destruction. Frexalimab is proming for multiple sclerosis, lupus erythematosus, Sjögrens syndrome and type I diabetes research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SAR441344; INX-021. CAS No. 2515463-86-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99625. | |
| Friedelin | Friedelin is derived from the leaves of Maytenus ilicifolia (Mart). Friedelin is an orally active non-competitive inhibitor of CYP3A4 , with IC 50 and K i values of 10.79 μM and 6.16 μM, respectively. Friedelin is also a competitive inhibitor of CYP2E1 , with IC 50 and K i values of 22.54 μM and 18.02 μM, respectively. Friedelin can be used in research related to inflammation, neurological diseases, and metabolic disorders [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 559-74-0. Pack Sizes: 5 mg. Product ID: HY-N4110. | |
| (-)-FRM-024 | (-)-FRM-024 is the (-)-isomer of FRM-024, a potent CNS-penetrant gamma secretase modulator that can be utilized in Alzheimers disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2085780-85-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-115726A. | |
| Frovatriptan succinate hydrate | Frovatriptan succinate hydrate ((R)-Frovatriptan succinate hydrate) is a potent, high affinity, selective and orally active 5-HT 1B ( pK 50 of 8.2) and 5-HT 1D receptor agonist. Frovatriptan succinate hydrate exhibits >10-fold selectivity for 5-HT 1B and 5-HT 1D over 5-HT 1A , 5-HT 1F , and 5-HT 7 and >1000-fold selectivity over other 5-HT, dopamine, histamine H 1 , and α1-adrenoceptor. Frovatriptan succinate hydrate has the potential for migraine research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Frovatriptan succinate hydrate; SB 209509 succinate hydrate; VML 251 succinate hydrate. CAS No. 158930-17-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-B1658A. | |
| Fructooligosaccharides | Fructooligosaccharides (Oligolevulose) is a beneficial sugar which can be produced by the microbial flora. Fructooligosaccharides had no significant effect on blood glucose, blood lipid and serum acetate in diabetic model [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Oligolevulose. CAS No. 308066-66-2. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-107863. | |
| Fructosamine hydrochloride | Fructosamine hydrochloride (D-Isoglucosamine hydrochloride) is a metabolic intermediate and component of cell membranes and cartilage. Fructosamine hydrochloride induces site-specific breaks in DNA chains, especially in the presence of Cu 2+ [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-Isoglucosamine hydrochloride. CAS No. 39002-30-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W414321. | |
| Fructose | Fructose is a simple ketonic monosaccharide found in many plants, where it is often bonded to glucose to form the disaccharide sucrose. Uses: Scientific research. Group: Natural products. Alternative Names: beta-D-Fructopyranose. CAS No. 7660-25-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N0395. | |
| Fructose (Standard) | Fructose (Standard) is the analytical standard of Fructose. This product is intended for research and analytical applications. Fructose is a simple ketonic monosaccharide found in many plants, where it is often bonded to glucose to form the disaccharide sucrose. Uses: Scientific research. Group: Natural products. CAS No. 7660-25-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0395R. | |
| Fructosyl-lysine | Fructosyl-lysine (Fructoselysine) is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. Fructosyl-lysine is the precursor to glucosepane, a lysine - arginine protein cross-link that can be an indicator in diabetes detection [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Fructoselysine. CAS No. 21291-40-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129380. | |
| Fructosyl-lysine dihydrochloride | Fructosyl-lysine (Fructoselysine) dihydrochloride is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. Fructosyl-lysine dihydrochloride is the precursor to glucosepane, a lysine - arginine protein cross-link that can be an indicator in diabetes detection [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Fructoselysine dihydrochloride. CAS No. 96192-35-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129380A. | |
| Frunevetmab | Frunevetmab (NV-02) is a felinized anti- nerve growth factor (NGF) monoclonal antibody with a K d of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: NV-02. CAS No. 1708936-80-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99627. | |
| Fruquintinib | Fruquintinib (HMPL-013) is a highly potent and selective VEGFR 1/2/3 inhibitor with IC 50 s of 33, 0.35, and 35 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HMPL-013. CAS No. 1194506-26-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19912. | |
| FSBA hydrochloride | FSBA hydrochloride is a useful reagent for the affinity labeling of adenine nucleotide binding proteins and is mainly applied in the study of purified The labeling and subsequent detection of these proteins can be blocked by including an excess of MgATP, which competes with FSBA for nucleotidebinding sites [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5'-p-Fluorosulfonylbenzoyladenosine. CAS No. 78859-42-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-123650. | |
| FSCPX | FSCPX is a potent and selective irreversible antagonist of A 1 adenosine receptor (A 1 AR) , with low nanomolar potency for binding to the A 1 AR. FSCPX could modify the effect of NBTI, a nucleoside transport inhibitor, by reducing the interstitial adenosine level in the guinea pig atrium [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 156547-56-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116042. | |
| FSK hydrochloride | FSK hydrochloride is fluorosulfonyloxybenzoyl-l-lysine, with a long and flexible aryl fluorosulfate-containing side chain that can reach protein sites that are difficult to reach by covalent linkage. FSK hydrochloride is a modified nanomolecule that targets the epidermal growth factor receptor (EGFR), creating a covalent binding that results in irreversible binding. FSK hydrochloride captures unknown enzyme-substrate interactions in living cells through genetically encoded chemical cross-linking, targeting residues beyond Cys, and cross-linking at the binding periphery. FSK hydrochloride enables the construction of bioreactive SuFEx systems for creating covalent bonds in different proteins in vitro and in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3033987-42-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-48999A. | |
| FT113 | FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC 50 of 213 nM for full-length recombinant human FASN enzyme. In cell-based assay, FT113 blocks FASN activity in BT474 cells (IC 50 , 90 nM). FT113 shows anti-proliferative activity, and exhibits anti-cancer activity both in vitro and in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1630808-89-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111551. | |
| Fuberidazole | Fuberidazole (BAY 33172; Furidazole) is a fungicide. Fuberidazole shows a synergistic effect with cucurbituril (CB) macromolecules, such as CB7 and CB8. Studies have shown that, CB8 induces pK a shifts on Fuberidazole. Fuberidazole significantly inhibits the growth of B. cinerea [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 33172; Furidazole. CAS No. 3878-19-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1843. | |
| Fucoidan | Fucoidan, a biologically active polysaccharide, is an efficient inhibitor of α-amylase and α-glucosidase. Anticoagulant, antitumor, antioxidant and antisteatotic activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 9072-19-9. Pack Sizes: 100 mg; 500 mg. Product ID: HY-132179. | |
| (-)-Fucose | (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-)-Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 6-Desoxygalactose; L-(-)-Fucose; L-Galactomethylose. CAS No. 2438-80-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N1480. | |
| (-)-Fucose (Standard) | (-)-Fucose (Standard) is the analytical standard of (-)-Fucose. This product is intended for research and analytical applications. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-)-Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth [2]. Uses: Scientific research. Group: Natural products. CAS No. 2438-80-4. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N1480R. | |
| Fucosterol | Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities [1] [2]. Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research [1]. Uses: Scientific research. Group: Natural products. CAS No. 17605-67-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N4103. | |
| Fucoxanthin | Fucoxanthin (all-trans-Fucoxanthin) is a marine carotenoid and shows anti-obesity, anti-diabetic, anti-oxidant, anti-inflammatory and anticancer activities [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Natural products. Alternative Names: all-trans-Fucoxanthin. CAS No. 3351-86-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2302. | |
| Fudosteine | Fudosteine is a cysteine derivative and a mucoactive agent. Fudosteine inhibits MUC5AC mucin hypersecretion by reducing MUC5AC gene expression [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13189-98-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0393. | |
| Fulacimstat | Fulacimstat is an orally available chymase inhibitor, with IC 50 s of 4, 3 nM for human and hamster chymase enzyme, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY1142524. CAS No. 1488354-15-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109059. | |
| Fullerene-C60 | Fullerene-C60, a representative of carbon nanocompounds, is suggested to be promising agent for application in photodynamic research due to its unique physicochemical properties. Fullerene-C60 probes the intramolecular dynamics of its electron and energy transfer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 99685-96-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W020768. | |
| Fulranumab | Fulranumab is a human IgG2 monoclonal antibody against nerve growth factor ( NGF ) and can be used for the research of pain [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 902141-80-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99200. | |
| Fulvestrant | Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC 50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER -positive MCF-7 cells with an IC 50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICI 182780; ZD 9238; ZM 182780. CAS No. 129453-61-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13636. | |
| Fulvestrant (Standard) | Fulvestrant (Standard) is the analytical standard of Fulvestrant. This product is intended for research and analytical applications. Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC 50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER -positive MCF-7 cells with an IC 50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICI 182780(Standard); ZD 9238(Standard); ZM 182780 (Standard). CAS No. 129453-61-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13636R. | |
| Fulvic Acid | Fulvic Acid is a natural product, which comes from humic substances produced by microorganisms in soil. Fulvic Acid can modulate the immune system, influence the oxidative state of cells, and improve gastrointestinal function. Fulvic Acid has the potential for researching chronic inflammatory diseases, including diabetes [1]. Uses: Scientific research. Group: Natural products. CAS No. 479-66-3. Pack Sizes: 1 mg. Product ID: HY-122515. | |
| Fulzerasib | Fulzerasib (GFH925) is an irreversible KRAS G12C inhibitor, has a synergistic anti-cancer effect with cetuximab (HY-P9905). [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IBI351; GFH925. CAS No. 2641747-54-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-152848. | |
| Fumagillin | Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV?1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity. Uses: Scientific research. Group: Natural products. Alternative Names: Amebacilin; NSC9168. CAS No. 23110-15-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-B0751. | |
| Fumaric acid | Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 110-17-8. Pack Sizes: 10 mM * 1 mL; 100 g. Product ID: HY-W015883. | |
| Fumaric acid disodium | Fumaric acid disodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Natural products. CAS No. 17013-01-3. Pack Sizes: 100 g. Product ID: HY-W015883A. | |
| Fumaric acid (Standard) | Fumaric acid (Standard) is the analytical standard of Fumaric acid. This product is intended for research and analytical applications. Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 110-17-8. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-W015883R. | |
| Fumitremorgin C | Fumitremorgin C is a potent and selective ABCG2/BRCP inhibitor. Uses: Scientific research. Group: Natural products. Alternative Names: 12α-Fumitremorgin C. CAS No. 118974-02-0. Pack Sizes: 10 mM * 1 mL; 250 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2143. | |
| Fumonisin B1 | Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 116355-83-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6719. | |
| Fumonisin B2 | Fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 116355-84-1. Pack Sizes: 1 mg. Product ID: HY-N6723. | |
| Funapide | Funapide (TV 45070; XEN402) is a potent inhibitor of the sodium channel Nav1.7 , Nav1.8 and other Nav channels expressed in the peripheral nervous system. Fornabil is an orally effective analgesic agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TV 45070; XEN402. CAS No. 1259933-16-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16723. | |
| Fura-2 AM | Fura-2 AM is a high affinity, intracellular, UV light-excitable and ratiometric fluorescent Ca 2+ (calcium ion) indicator. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Fura-2 Acetoxymethyl ester. CAS No. 108964-32-5. Pack Sizes: 100 μg; 1 mg. Product ID: HY-101897. | |
| Fura-2 pentapotassium | Fura-2 pentapotassium is a scaled fluorescent dye that can be used for intracellular calcium imaging with the K d value of 140 nM. Fura-2 pentapotassium has an emission wavelength of 510 nm and excitation wavelengths of 340 nm or 380 nm and the ratio of 340/380 fluorescence intensity is proportional to the intracellular Ca 2+ level [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 113694-64-7. Pack Sizes: 500 μg; 1 mg. Product ID: HY-D0110A. | |
| Furafylline | Furafylline is a potent and selective inhibitor of human cytochrome P450IA2 with an IC 50 of 0.07 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 80288-49-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107204. | |
| Furaltadone hydrochloride | Furaltadone hydrochloride is an orally active antibacterial agent that can be used for the study of intestinal Salmonella infections. Furaltadone has in vitro inhibitory effects on Staphylococcus. In addition, Furaltadone shows inhibitory effects on allergic reactions [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Altafur hydrochloride. CAS No. 3759-92-0. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B1148. | |
| Furamidine dihydrochloride | Furamidine dihydrochloride (DB75 dihydrochloride) is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC 50 of 9.4 μM. Furamidine dihydrochloride is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC 50 s of 166 μM, 283 μM, and >400 μM, respectively). Furamidine dihydrochloride is a potent, reversible and competitive tyrosyl-DNA phosphodiesterase 1 (TDP-1) inhibitor. Inhibition of TDP-1 by Furamidine dihydrochloride is effective both with single- and double-stranded DNA substrates but is slightly stronger with the duplex DNA. Furamidine dihydrochloride is also an antiparasite agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DB75 dihydrochloride; NSC 305831 dihydrochloride. CAS No. 55368-40-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110137. | |
| Furaneol | Furaneol is mainly isolated from American grape ( Vitis labrusca ) and its hybrid grape. Furaneol is an important aroma compound in fruits and contribute to the strawberry-like note in some wines [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Strawberry furanone. CAS No. 3658-77-3. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-N7093. | |
| Furaprofen | Furaprofen (R803) is an effective HCV replication inhibitor. Furaprofen (R803) is substantially more potent against genotype 1a and 1b replicons ( EC 50 , ~30 nM) than against the genotype 2a replicon (EC 50 , ~1,000 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: R803. CAS No. 67700-30-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00213. | |
| Fura Red AM | Fura Red AM is a fluorescent probe that can be used to visualize [Ca(2+)] distribution in the cytoplasm of undifferentiated cells. Fura Red AM operates at an excitation wavelength of 488 nm [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 218280-33-2. Pack Sizes: 1 mg. Product ID: HY-D1903. | |
| Furazolidone | Furazolidone is a monoamine oxidase (MAO) inhibitor with antiproliferative, apoptosis-inducing and differentiation-promoting activities. Furazolidone may inhibit leukemia fusion protein-mediated bone marrow transformation by upregulating the stability of the tumor suppressor protein p53. Furazolidone exhibits anti-leukemic activity in acute myeloid leukemia (AML) cell lines and can be used for anti-AML research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67-45-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1336. | |
| Furazolidone (Standard) | Furazolidone (Standard) is the analytical standard of Furazolidone. This product is intended for research and analytical applications. Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity. It inhibits AML1-ETO transformed cells with an IC50 of 12.7 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 67-45-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B1336R. | |
| Furegrelate sodium | Furegrelate Sodium (U-63557A) is a potent, orally available, and selective thromboxane synthase inhibitor. Furegrelate Sodium inhibits human platelet microsomal thromboxane A2 (TxA2) synthase with an IC 50 of 15 nM. Furegrelate Sodium is being developed as an antiplatelet agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: U-63557A. CAS No. 85666-17-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-106080A. | |
| Furfuryl acetate | Furfuryl acetate can be used in the synthesis of 5-acetoxymethyl-2-vinylfuran and 5-hydroxymethyl-2-vinylfuran [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 623-17-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W010321. | |
| Furosemide | Furosemide is a potent and orally active inhibitor of Na + /K + /2Cl - (NKCC) cotransporter , NKCC1 and NKCC2 [1]. Furosemide is also a GABA A receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54-31-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0135. | |
| Furosemide sodium | Furosemide sodium is a potent and orally active inhibitor of Na + /K + /2Cl - (NKCC) cotransporter , NKCC1 and NKCC2 [1]. Furosemide sodium is also a GABA A receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 41733-55-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0135A. | |
| Furosemide (Standard) | Furosemide (Standard) is the analytical standard of Furosemide. This product is intended for research and analytical applications. Furosemide is a potent and orally active inhibitor of Na + /K + /2Cl - (NKCC) cotransporter , NKCC1 and NKCC2 [1]. Furosemide is also a GABA A receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54-31-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0135R. | |
| Fusaric acid | Fusaric acid is a potent dopamine β-hydroxylase inhibitor. Uses: Scientific research. Group: Natural products. CAS No. 536-69-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-128483. | |
| Fusicoccin | Fusicoccin (Fusicoccin A), a fungal pytotoxin, is a stabilizer of specific 14-3-3 protein-protein interactions. Fusicoccin sabilizes H + -ATPase/14-3-3 cmplex in pants, maintaining the enzyme in activated state. Fusicoccin also stabilizes 14-3-3 protein interactions with binding partners containing a C-terminal 14-3-3 recognition motif (a mode 3 motif), such as ERα, GPIbα, TASK3, CTFR, and p53. Fusicoccin induces apoptosis in cancer cells and has anticancer activity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Fusicoccin A. CAS No. 20108-30-9. Pack Sizes: 1 mg. Product ID: HY-122815. | |
| Fusidic acid | Fusidic acid (Fusidate) a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid has no corticosteroid effects. Fusidic acid inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome. Fusidic acid holds promise for research in anticancer and anti-infective applications. [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Fusidate; SQ-16603. CAS No. 6990-6-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1350. | |
| Fusion Inhibitory Peptide | Fusion Inhibitory Peptide (Z-D-Phe-Phe-Gly-OH, FIP, Virus Replication Inhibitory Peptide) is a potent inhibitor of the virus replication, by inhibiting the membrane fusing activity of a viral glycoprotein [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Z-D-Phe-Phe-Gly-OH; FIP; Virus Replication Inhibitory Peptide. CAS No. 75539-79-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-114437. | |
| Fustin | Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) is a potent amyloid β (Aβ) inhibitor. Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) increases the expression of acetylcholine (ACh) levels, choline acetyltransferase (ChAT) activity, and ChAT gene induced by Aβ (1-42). Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) decreases in acetyl cholinesterase (AChE) activity and AChE gene expression induced by Aβ (1-42). Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) increases muscarinic M1 receptor gene expression and muscarinic M1 receptor binding activity. Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) can be used for Alzheimer's disease research [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone. CAS No. 20725-03-5. Pack Sizes: 1 mg. Product ID: HY-N8376. | |
| Futibatinib | Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC 50 s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC 50 s (wild-type FGFR2=0.9?nM; V5651=1-3?nM; N550H=3.6?nM; E566G=2.4?nM) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAS-120. CAS No. 1448169-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100818. | |
| Futoquinol | Futoquinol is a neolignan isolated from the dried aerial parts of Piper kadsura (Piperaceae). Futoquinol potently inhibits NO production in microglia cells. Futoquinol has anti-neuroinflammatory activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 28178-92-9. Pack Sizes: 1 mg. Product ID: HY-N3915. | |
| Futuximab | Futuximab is a chimeric monoclonal antibody targeting non-overlapping epitopes on EGFR. Futuximab has antineoplastic activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1310460-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99628. | |
| Fuzapladib | Fuzapladib (IS-741), an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IS-741. CAS No. 141283-87-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19151. | |
| Fuzapladib sodium | Fuzapladib (IS-741) sodium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib sodium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib sodium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IS-741 sodium. CAS No. 141284-73-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19151A. | |
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