MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Surfactin | Surfactin is a potent cyclic lipopeptide biosurfactants consists of four isomers (Surfactin A, B, C and D), which mediates flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. Surfactin can act as an antimicrobial adjuvant with anti- bacterial , anti- fungal , antimycoplasma and hemolytic effects [1] [2]. Surfactin also has antiviral activity against a variety of enveloped viruses [3]. Uses: Scientific research. Group: Natural products. CAS No. 252023-70-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-129555. |  |
| Surfen dihydrochloride | Surfen dihydrochloride is a potent HS (heparan sulfate) antagonist. Surfen binds to glycosaminoglycans. Surfen neutralizes the anticoagulant activity of both unfractionated and low molecular weight heparins. Surfen affects sulfation of heparin and inhibits degradation by heparin lyases. Surfen inhibits FGF2 binding and signaling. Surfen inhibits cell attachment, and virus infection [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aminoquinuride dihydrochloride. CAS No. 5424-37-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122704A. | |
| Survodutide | Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC 50 s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake [1]. Uses: Scientific research. Group: Peptides. Alternative Names: BI 456906. CAS No. 2805997-46-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4146. | |
| Sutezolid | Sutezolid (PNU-100480), an orally active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis. Sutezolid has potent activity against mycobacteria , and is used for the research of drug-resistant tuberculosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNU-100480; U-100480; PF-02341272. CAS No. 168828-58-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10392. | |
| Sutimlimab | Sutimlimab, a first-in-class complement protein component 1, s subcomponent ( C1s ) inhibitor, can be used for the research of cold agglutinin disease. C1s is a serine protease which cleaves C4 and C2 to form the C3 convertase [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2049079-64-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99050. | |
| Suvecaltamide | Suvecaltamide (MK-8998) is a selective T-type calcium channel inhibitor with oral efficacy. Suvecaltamide exhibits no cytotoxicity in myeloma cell lines and does not affect the antitumor efficacy of Bortezomib (BTZ). Suvecaltamide reverses BTZ-induced peripheral neuropathy (CIPN) in mouse and rat models, and helps inhibit myeloma growth [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-8998; CX-8998; JZP385. CAS No. 953778-58-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101096. | |
| SUVN-911 | SUVN-911 is a potent, selective, brain penetrated and orally bioavailable neuronal nicotinic acetylcholine α4β2 receptor antagonist, with a K i of 1.5 nM. SUVN-911 has antidepressant activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2414674-71-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136146. | |
| Suvratoxumab | Suvratoxumab (MEDI4893) is a long-acting, high-affinity human anti-α-toxin monoclonal antibody (IgG1κ type). Suvratoxumab potently neutralizes α-toxin, a key S. aureus virulence factor. Suvratoxumab improves survival and reduces lung injury in an immunocompromised mice model of pneumonia. Suvratoxumab also enhances the antibacterial activity of Vancomycin (HY-B0671) or Linezolid (HY-10394) [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI4893. CAS No. 1629620-18-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99583. | |
| Suxibuzone | Suxibuzone is a compound used for the study of joint and muscle pain, and it is a prodrug of the non-steroidal anti-inflammatory drug Phenylbutazone. Uses: Scientific research. Group: Signaling pathways. CAS No. 27470-51-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1079. | |
| Suzetrigine | Suzetrigine (VX-548) is an orally active and highly selective Na V 1.8 inhibitor that acts as an analgesic. Suzetrigine is also a blocker of sodium channel protein type 10 subunit alpha. Suzetrigine is promising for research of acute pain after abdominoplasty and bunionectomy [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-548. CAS No. 2649467-58-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148800. | |
| (S)-Verapamil hydrochloride | (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-(-)-Verapamil hydrochloride. CAS No. 36622-28-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135336A. | |
| SW033291 | SW033291 is a potent and high-affinity inhibitor of 15-PGDH with a Ki of 0.1 nM. SW033291 increases prostaglandin PGE2 levels in bone marrow and other tissues. SW033291 also promotes tissue regeneration[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 459147-39-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16968. | |
| SW-100 | SW-100, a selective histone deacetylase 6 (HDAC6) inhibitor with an IC 50 of 2.3 nM, shows at least 1000-fold selectivity for HDAC6 relative to all other HDAC isozymes. SW-100 displays a significantly improved ability to cross the blood-brain-barrier [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2126744-35-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-115475. | |
| SW106065 | SW106065 is an apoptosis inducer in malignant peripheral nerve sheath tumors (MPNST). SW106065 inhibits ATP consumption of sMPNST and other models of MPNST with an EC50 of 1 μM. SW106065 can be used for MPNST research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 62289-81-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124778. | |
| Swainsonine | Swainsonine (Tridolgosir) is an natural indolizidine alkaloid, a potent and reversible α-mannosidase inhibitor. Swainsonine induces apoptosis and cell cycle arrest at G2/M phase. Swainsonine shows anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Tridolgosir. CAS No. 72741-87-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6722. | |
| Sweroside | Sweroside, isolated from Lonicera japonica, exhibits cytoprotective, anti-osteoporotic, and hepatoprotective effect [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 14215-86-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0806. | |
| Swertiamarin | Swertiamarin is an orally active natural product with hypoglycemic, lipid-lowering, anti-rheumatic, and antioxidant activities. Swertiamarin can regulate the levels of pro-inflammatory cytokines, MMP , and NF-κB , and promote osteoblast proliferation. Swertiamarin has antioxidant and hepatoprotective effects against carbon tetrachloride induced rat liver toxicity through the Nrf2/HO-1 pathway. Swertiamarin can attenuate inflammatory mediators by regulating JAK2/STAT3 transcription factors in adjuvant induced arthritis rats. Swertiamarin can be used in the research of diabetes and arthritis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 17388-39-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0807. | |
| SWTX-143 | SWTX-143 is an orally active YAP/TAZ-TEAD inhibitor that binds to the palmitoylation pocket of all four TEAD isoforms. SWTX-143 causes irreversible and specific inhibition of the transcriptional activity of YAP/TAZ-TEAD and shows antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2766575-48-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155338. | |
| SX-682 | SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1648843-04-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119339. | |
| SY-5609 | SY-5609 (CDK7-IN-3) is an orally active, highly selective, noncovalent CDK7 inhibitor with a KD of 0.065 nM. SY-5609 shows poor inhibition on CDK2 (Ki=2600 nM), CDK9 (Ki=960 nM), CDK12 (Ki=870 nM). SY-5609 induces apoptosis in tumor cells and has antitumor activity[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDK7-IN-3. CAS No. 2417302-07-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138293. | |
| SYBR Green II | SYBR Green II is a fluorescent nucleic acid dye that mainly binds single-stranded nucleotides. SYBR Green II is sensitive to oligonucleotides or larger nucleic acid polymers in a variety of cells and gels. SYBR Green II can be used to study cell structure, membrane integrity or function, and cell cycle distribution. Wavelength 484/515 nm [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 195199-08-7. Pack Sizes: 50 μL. Product ID: HY-D1098. | |
| SYD5115 | SYD5115 is an orally available TSH-R antagonist[1][2]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158100. | |
| SYHA1813 | SYHA1813 is a dual inhibitor of CSF1R and VEGFR. SYHA1813 has potent antitumor activity against GBM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1807466-30-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161025. | |
| Synaptamide | Synaptamide (Dehydroepiandrosteron; DHEA) is an endogenous metabolite and structural analogue of Anandamide. Synaptamide binds to both the cannabinoid-1 and 2 (CB1 and CB2) cannabinoid receptors and has anti-inflammatory properties. Synaptamide is the first small-molecule endogenous ligand of an adhesion G protein-coupled receptor (aGPCR) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Docosahexaenoyl ethanolamine (DHEA); Docosahexaenoyl ethanolamide. CAS No. 162758-94-3. Pack Sizes: 5 mg (67 mM * 200 μL in Ethanol); 10 mg (67 mM * 400 μL in Ethanol). Product ID: HY-100197. | |
| Synephrine | Synephrine (Oxedrine), an alkaloid, is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium. Synephrine is a sympathomimetic compound and can be used for weight loss [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Oxedrine. CAS No. 94-07-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0132. | |
| Synephrine hydrochloride | Synephrine (Oxedrine) hydrochloride, an alkaloid, is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium. Synephrine hydrochloride is a sympathomimetic compound and can be used for weight loss [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Oxedrine hydrochloride. CAS No. 5985-28-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N0132A. | |
| Synta66 | Synta66 is an inhibitor of store-operated calcium entry channel Orai, which forms the pore of the CRAC channel, and used for the research of neurological disease. Uses: Scientific research. Group: Signaling pathways. CAS No. 835904-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111325. | |
| SynuClean-D | SynuClean-D (SC-D) is an inhibitor of ?-synuclein aggregation, disrupts mature amyloid fibrils, prevents fibril propagation, and abolishes the degeneration of dopaminergic neurons in an animal model of Parkinsons disease[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC-D. CAS No. 685121-45-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-124876. | |
| Syringaldehyde | Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis [1]. Syringaldehyde moderately inhibits COX-2 activity with an IC 50 of 3.5 μg/mL [2]. Anti-hyperglycemic and anti-inflammatory activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 134-96-3. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-N1390. | |
| (-)-Syringaresinol | (-)-Syringaresinol, is the isoform of Syringaresinol (HY-N8307), which can be found in stems of Annona Montana , possesses anti-cancer activity. Syringaresinol is an activator of NO synthase phosphorylation and induces vasodilation. Syringaresinol also inhibits the NF-κB pathway and exerts anti-inflammatory activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 6216-81-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-126066. | |
| (+)-Syringaresinol | (+)-Syringaresinol, a lignan, is a NFAT transcription factor inhibitor, with an IC 50 of 329.4 μM. (+)-Syringaresinol also can be used for the research of lymphocytic leukemia [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 21453-69-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-126030. | |
| Syringetin | Syringetin, a flavonoid derivative, is associated with increased BMP-2 production. Syringetin stimulates osteoblast differentiation at various stages, from maturation to terminally differentiated osteoblasts [1]. Uses: Scientific research. Group: Natural products. CAS No. 4423-37-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8920. | |
| Syringetin-3-O-glucoside | Syringetin-3-O-glucosid (Syringetin 3-O-β-D-glucoside), a flavonol glycoside, shows relatively weak DPPH and ABTS radical scavenging activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Syringetin 3-O-β-D-glucoside. CAS No. 40039-49-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N8194. | |
| Syringic acid | Syringic acid is correlated with high antioxidant activity and inhibition of LDL oxidation. Uses: Scientific research. Group: Natural products. CAS No. 530-57-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-N0339. | |
| Syringic acid (Standard) | Syringic acid (Standard) is the analytical standard of Syringic acid. This product is intended for research and analytical applications. Syringic acid is correlated with high antioxidant activity and inhibition of LDL oxidation. Uses: Scientific research. Group: Natural products. CAS No. 530-57-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0339R. | |
| Syringin | Syringin (Eleutheroside B) is an active natural phenolic glycoside possessing various pharmacological activities, including anti-inflammatory, anti-irradiation, anti-osteoporosis and anticancer activities. Syringin also can be used to enhance memory, relieve fatigue, improve human cognition and protect ischemia heart against cerebrovascular damage, etc [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Eleutheroside B. CAS No. 118-34-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0824. | |
| Syrosingopine | Syrosingopine (Su 3118) is an orally active lactate transporters (MCT1/MCT4) dual inhibitor, which can reduce glycolysis and induce synthetic lethality in cancer cells when combine with metformin. Syrosingopine shows anti-hypertensive activity by depleting peripheral stores of norepinephrine[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Su 3118. CAS No. 84-36-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N4115. | |
| Systemin | Systemin, an 18-amino acid polypeptide, has been isolated from tomato leaves that is a powerful inducer of over 15 defensive genes. Uses: Scientific research. Group: Peptides. CAS No. 137181-56-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0279. | |
| SZL P1-41 | SZL P1-41 is a specific Skp2 inhibitor, binds to the F-box domain of Skp2 to prevent Skp1 association and Skp2 SCF complex formation. SZL P1-41, like Skp2 deficiency, augments p27-mediated apoptosis/senescence, while it impairs Akt-driven glycolysis. Anti-tumor activities[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 222716-34-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100237. | |
| T-00127_HEV1 | T-00127_HEV1 is a phosphatidylinositol 4-kinase III beta ( PI4KB ) inhibitor with an IC 50 of 60 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 900874-91-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108313. | |
| T0070907 | T0070907 is a potent PPAR? antagonist with a Ki of 1 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 313516-66-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13202. | |
| T01-1 | T01-1 is an anticancer agent (camptothecin derivative) with good anti-proliferative activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KL610023. CAS No. 2356229-14-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148185. | |
| T025 | T025 is an orally active and highly potent inhibitor of Cdc2-like kinase (CLKs), with Kd values of 4.8, 0.096, 6.5, 0.61, 0.074, 1.5 and 32 nM for CLK1, CLK2, CLK3, CLK4, DYRK1A, DYRK1B and DYRK2, respectively. T025 induces caspase-3/7-mediated cell apoptosis. T025 reduces CLK-dependent phosphorylation. T025 exerts anti-proliferative activities in both hematological and solid cancer cell lines (IC50 values: 30-300 nM). T025 has an anti-tumor efficiency, mainly for MYC-driven disease research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2407433-00-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112296. | |
| T0901317 | T0901317 is an orally active and highly selective LXR agonist with an EC50 of 20 nM for LXR?[1]. T0901317 activates FXR with an EC50 of 5 ?M[2]. T0901317 is ROR? and ROR? dual inverse agonist with Ki values of 132 nM and 51 nM, respectively[3]. T0901317 induces apoptosis and inhibits the development of atherosclerosis in low-density lipoprotein (LDL) receptor-deficient mice[4][5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 293754-55-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10626. | |
| T16Ainh-A01 | T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 μM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 552309-42-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100612. | |
| T2AA | T2AA is a monoubiquitinated proliferating cell nuclear antigen (PCNA) inhibitor that prevents DNA repair, increases double-strand break (DSB) formation and promotes necroptosis and cell cycle arrest in G1 phase[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1380782-27-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110111. | |
| T-518 | T-518 is an orally active, BBB-penetrant and potent DFMO-based HDAC6 inhibitor with high selectivity (IC50 = 36 nM). T-518 improves axonal transport. T-518 ameliorates object recognition deficit. T-518 can be studied in research for Alzheimers disease and tauopathy[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2276680-91-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161307. | |
| T-5224 | T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors. T-5224 inhibits the IL-1β-induced up-regulation of Mmp-3, Mmp-13 and Adamts-5 transcription [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 530141-72-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12270. | |
| T5342126 | T-5342126 is a toll-like receptor 4 (TLR4) antagonist. It reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells ( IC 50 =27.8 μM), as well as decreases LPS-induced IL-8, TNF-α, and IL-6 production in isolated human whole blood ( IC 50 s=110.5, 315.6, and 318.4 μM, respectively). T-5342126 (82 mg/kg) reduces ethanol intake and the abundance of ionized calcium-binding adapter molecule 1 (Iba1), a marker of microglial activation, in the central nucleus of the amygdala in ethanol-dependent mice. Uses: Scientific research. Group: Signaling pathways. CAS No. 956507-49-6. Pack Sizes: 1 mg (21.83 mM * 100 μL in Methyl acetate); 5 mg (21.83 mM * 500 μL in Methyl acetate); 10 mg (21.83 mM * 1 mL in Methyl acetate). Product ID: HY-123789. | |
| T6167923 | T6167923 is a selective inhibitor of MyD88-dependent signaling pathways. T6167923 directly binds to Toll/IL1 receptor (TIR) domain of MyD88 and disrupts MyD88 homodimeric formation. T6167923 inhibits NF-?B driven Staphylococcus enterotoxin AP (SEAP) activity, and improves anti-inflammatory activity with IC50s of 2.7 ?M, 2.9 ?M, 2.66 ?M and 2.66 ?M for IFN-?, IL-1?, IL-6 and TNF-?, respectively[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2437475-16-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19744. | |
| T7 RNA polymerase | T7 RNA polymerase is a polymerase expressed by Escherichia coli from the RNA polymerase gene of T7 bacteriophage. T7 RNA polymerase is highly specific and involved in in vitro transcription (IVT) of mRNA. In the presence of Mg 2+ , T7 RNA polymerase only uses the single-stranded or double-stranded DNA containing the T7 promoter sequence as a template, and uses NTP as a substrate to synthesize RNA complementary to the single-stranded DNA downstream of the promoter [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9014-24-8. Pack Sizes: 1 KU; 5 KU. Product ID: HY-E70090. | |
| T7 Tag Peptide | T7 Tag Peptide is a protein tag derived from the N-terminal 11 residues of the major T7 capsid protein, gp 10. T7 Tag Peptide can be used in different immunoassays as well as affinity purification [1]. Uses: Scientific research. Group: Peptides. CAS No. 245445-88-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0327. | |
| T807 | T807 a novel tau positron emission tomography (PET) tracer. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AV-1451. CAS No. 1415379-56-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101184. | |
| T863 | T863 is an orally active, selective and potent DGAT1 (acyl-CoA:diacylglycerol acyltransferase 1) inhibitor with an IC50 of 15 nM. T863 has no inhibitory activity against human MGAT3, human DGAT2, or human MGAT2. T863 interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 701232-20-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32219. | |
| TA-02 | TA-02, an analog of SB 203580 (HY-10256), is a p38 MAPK inhibitor with an IC 50 of 20 nM. TA-02 especially inhibits TGFBR-2. TA-02 exhibits similar cardiogenic properties as SB 203580 and SB 202190 (HY-10295) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1784751-19-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100115. | |
| TA-316 | TA-3166 (Megakaryocytes/platelets inducing agent) is a novel chemically synthesized c-MPL agonist (CMA) and thrombopoietin (TPO) receptor agonist. TA-316 enhances ex vivo platelet generation from human-induced pluripotent stem (iPS) cells[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Megakaryocytes/platelets inducing agent. CAS No. 1429321-13-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112486. | |
| Tabalumab | Tabalumab (LY2127399) is a human anti- BAFF ( B-cell activating factor ) monoclonal antibody (IgG4 type) with neutralising activity against membrane bound and soluble BAFF. Tabalumab can be used in studies of autoimmune diseases such as rheumatoid arthritis, renal failure and systemic lupus erythematosus [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY2127399. CAS No. 1143503-67-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99220. | |
| Tabersonine | Tabersonine is an indole alkaloid mainly isolated from Catharanthus roseus. Tabersonine disrupts Aβ(1-42) aggregation and ameliorates Aβ aggregate-induced cytotoxicity. Tabersonine has anti-inflammatory activities and acts as a potential therapeutic candidate for the treatment of ALI/ARDS [1]. Uses: Scientific research. Group: Natural products. CAS No. 4429-63-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N1431. | |
| TACA | TACA (trans-4-Aminocrotonic acid) is a potent agonist of GABA A and GABA C receptors ( K D = 0.6 μM). TACA also is GABA uptake inhibitor and substrate for GABA-T. TACA produces late biphasic responses in the MPG neurons [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: trans-4-Aminocrotonic acid. CAS No. 38090-53-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100800. | |
| Tacalcitol | Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3. CAS No. 57333-96-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-32337. | |
| Tacalcitol monohydrate | Tacalcitol monohydrate (1,24(R)-Dihydroxyvitamin D3; 1. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1,24(R)-Dihydroxyvitamin D3 monohydrate. CAS No. 93129-94-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-32338. | |
| Tacedinaline | Tacedinaline (N-acetyldinaline) is an inhibitor of the histone deacetylase ( HDAC ) with IC 50 s of 0.9, 0.9, 1.2 μM for recombinant HDAC 1, 2 and 3 respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-acetyldinaline; CI-994; Goe-5549. CAS No. 112522-64-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-50934. | |
| Tacrine | Tacrine is an effective oral acetylcholine (AChE) inhibitor ( IC 50 = 109 nM) and also acts as an active substrate for CYP1A2. Tacrine can restore cognitive dysfunction in elderly rats. Tacrine can cause liver toxicity and is used in research related to Alzheimer's disease [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 321-64-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-111338. | |
| Tacrine hydrochloride | Tacrine hydrochloride is a potent inhibitor of both AChE and BChE , with IC 50 s of 31 nM and 25.6 nM, respectively. Tacrine hydrochloride is also a NMDAR inhibitor, with an IC 50 of 26 μM. Tacrine hydrochloride can be used for the research of Alzheimers disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1684-40-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1488. | |
| Tacrine hydrochloride (hydrate) | Tacrine hydrochloride (hydrate) is an inhibitor of both acetyl ( AChE ) and butyryl-cholinestrase ( BChE ) with IC 50 s of 31 nM and 25.6 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 206658-92-6. Pack Sizes: 100 mg. Product ID: HY-B2244. | |
| Tacrolimus | Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase , which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: FK506; Fujimycin; FR900506. CAS No. 104987-11-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13756. | |
| Tacrolimus monohydrate | Tacrolimus monohydrate (FK506 monohydrate), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase , which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: FK506 monohydrate; Fujimycin monohydrate; FR900506 monohydrate. CAS No. 109581-93-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13756A. | |
| Tadalafil | Tadalafil (IC-351) is a PDE5 inhibitor with an IC 50 value of 1.8 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IC-351. CAS No. 171596-29-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-90009A. | |
| Tafamidis | Tafamidis is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC 50 s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 594839-88-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14852. | |
| Tafamidis meglumine | Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC 50 s of 2.7-3.2 μM. Tafamidis meglumine inhibits amyloidogenesis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fx-1006A. CAS No. 951395-08-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14852A. | |
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