MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Tanimilast | Tanimilast (CHF-6001) is a novel highly potent and selective phosphodiesterase 4 inhibitor( IC 50 =0.026 ± 0.006 nM) with robust anti-inflammatory activity and suitable for topical pulmonary administration.Tanimilast is used for the research of obstructive lung diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CHF-6001. CAS No. 1239278-59-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19929. |  |
| Tannase | Tannase, also known as tanninyl hydrolase, is an enzyme that can hydrolyze ester bonds and tannic acid side bonds, releasing glucose and gallic acid, and is outstanding in clarifying wine and fruit juice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9025-71-2. Pack Sizes: 1 g; 5 g. Product ID: HY-P2877. | |
| Tannic acid | Tannic acid is a novel hERG channel blocker with IC 50 of 3.4 μM. Uses: Scientific research. Group: Natural products. CAS No. 1401-55-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B2136. | |
| Tanruprubart | ANX005 is a human-derived antibody expressed in CHO cells, targeting C1q. ANX005 contains huIgG1 heavy chains and hu? light chains, with a predicted molecular weight (MW) of 145 kDa. The isotype control for ANX005 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ANX005. CAS No. 2065212-40-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990545. | |
| tans-4-Hydroxy-D-proline hydrochloride | tans-4-Hydroxy-D-proline hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). tans-4-Hydroxy-D-proline hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PR. Uses: Scientific research. Group: Signaling pathways. CAS No. 142347-81-7. Pack Sizes: 1 g; 5 g. Product ID: HY-W003511. | |
| Tanshinone I | Tanshinone I is an inhibitor of type IIA human recombinant sPLA 2 ( IC 50 =11 μM) and rabbit recombinant cPLA 2 ( IC 50 =82 μM). Uses: Scientific research. Group: Natural products. Alternative Names: Tanshinone A. CAS No. 568-73-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0134. | |
| Tanshinone IIA | Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF / VEGFR2. Uses: Scientific research. Group: Natural products. Alternative Names: Dan Shen ketone. CAS No. 568-72-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0135. | |
| Tanshinone IIA sulfonate sodium | Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA, which acts as an inhibitor of store-operated Ca 2+ entry (SOCE), and is used to treat cardiovascular disorders. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium Tanshinone IIA sulfonate; Tanshinone IIA sodium sulfonate. CAS No. 69659-80-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N1370. | |
| Tanuxiciclib | Tanuxiciclib is a cyclin dependent kinase (CDK) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1983983-64-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145599. | |
| Tanzisertib | Tanzisertib (CC-930) is a potent JNK1/2/3 inhibitor with IC50s of 61/7/6 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-930. CAS No. 899805-25-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15495. | |
| TAO Kinase inhibitor 1 | TAO Kinase inhibitor 1 (compound 43) is a selective, ATP-competitive thousand-and-one amino acid kinases (TAOK) inhibitor with IC50s of 11 to 15 nM for TAOK1 and 2, respectively. TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 43. CAS No. 850467-66-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112136. | |
| TAPI-0 | TAPI-0 is a TACE (TNF-α converting enzyme; ADAM17) inhibitor with an IC 50 of 100 nM. TAPI-0 is a MMP inhibitor and also attenuates TNF-α processing [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 163958-73-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-118694. | |
| TAPI-1 | TAPI-1 is a TACE (ADAM17) inhibitor and blocks the shedding of several cell surface proteins[1]. TAPI-1 is also a metalloproteinase (MMP) inhibitor[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 163847-77-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-16657. | |
| TAPI-2 | TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease ( MMP ), tumour necrosis factor α -converting enzyme ( TACE ) and a disintegrin and metalloproteinase ( ADAM ), with an IC 50 of 20 μM for MMP [1]. TAPI-2 blocks the entry of infectious SARS-CoV [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TNF Protease Inhibitor 2. CAS No. 187034-31-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100211. | |
| Tapinarof | Tapinarof (WBI-1001) is a natural aryl hydrocarbon receptor ( AhR ) agonist with an EC 50 of 13 nM. Tapinarof resolves skin inflammation in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WBI-1001; Benvitimod; GSK2894512. CAS No. 79338-84-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-109044. | |
| Taplucainium chloride | Taplucainium chloride is a Sodium Channel blocker. Taplucainium chloride exhibits 70-95% inhibition at 10μM. Taplucainium chloride can be used as an analgesic agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2489565-37-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148802. | |
| Tapotoclax | Tapotoclax (AMG-176) is a potent, selective and orally active MCL-1 inhibitor, with a Ki of 0.13 nM[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMG-176. CAS No. 1883727-34-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101565. | |
| TAPS | TAPS is a biological buffer, remain lysozyme native structure intact and prevents thermal denaturation against high temperatures. TAPS exhibits pK a value of 8.1, while the half-maximum values of connexin channel activity is 8.5 (pH) [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 29915-38-6. Pack Sizes: 25 g; 50 g. Product ID: HY-D0877. | |
| TAPSO | TAPSO is a common biological buffer, a pH stabilization reagent, with effective pH ranging from 7-8, and pKa values ranging from 7.5 - 9.0. TAPSO contains Tris groups and exhibits quite reactive activity with zwitterionic glycine peptides [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 68399-81-5. Pack Sizes: 25 g; 100 g. Product ID: HY-D0878. | |
| Taq DNA polymerase | Taq DNA polymerase is a thermostable DNA polymerase that can be used in PCR [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2304873-37-6. Pack Sizes: 500 U. Product ID: HY-E70086. | |
| Taranabant | Taranabant is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist that inhibits the binding and functional activity of various agonists, with a binding Ki of 0.13 nM for the human CB1R in vitro. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0364. CAS No. 701977-09-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-10013. | |
| Taraxasterol | Taraxasterol is a pentacyclic triterpenoid compound isolated from Taraxacum mongolicum. Taraxasterol is an LXRα activator, with metabolic and anti-inflammatory effects. Taraxasterol may be used in research on immune-inflammatory diseases [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1059-14-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N1178. | |
| Taraxasteryl acetate | Taraxasteryl acetate is isolated from P. sagittalis ,and has a broad spectrum of anti-inflammatory activity. Taraxasterol acetate promotes RNF31 degradation by activating autophagy. Taraxasteryl acetate relieves dextran, zymosan and arachidonic acid induced rat hind-paw edema. Taraxasteryl acetate can be used for the topical inflammation treatment [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 6426-43-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2478. | |
| Taraxerol | Taraxerol is isolated from Taraxacum mongolicum , and has anti-inflammtory and anti-cancer effects. Taraxerol attenuates acute inlammation through inhibition of NF-κB signaling pathway. Taraxerol induces cell apoptosis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 127-22-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2477. | |
| Taraxerone | Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase ( ADH ) and acetaldehyde dehydrogenase ( ALDH ) activities with EC 50 values of 512.42 and 500.16 μM, respectively [1]. Uses: Scientific research. Group: Natural products. CAS No. 514-07-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1177. | |
| Tarcocimab | Tarcocimab (OG1953) is a humanized anti- VEGFA monoclonal antibody (IgG1 type). Tarcocimab is available for research in retinal vein occlusion (RVO) and wet age-related macular degeneration (AMD). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: OG1953. CAS No. 2408661-40-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99576. | |
| Tarenflurbil | Tarenflurbil ((R)-Flurbiprofen) is the R-enantiomer of the racemate NSAID Flurbiprofen, Tarenflurbil ((R)-Flurbiprofen) inhibits the binding of [ 3 H]9-cis-RA to RXRα LBD with IC 50 of 75 μM. Tarenflurbil can be used for Alzheimer's disease research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Flurbiprofen; MPC7869. CAS No. 51543-40-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-10291. | |
| Tarextumab | Tarextumab (OMP-59R5) is an anti- Notch2/3 fully human IgG2 monoclonal antibody. Tarextumab shows anti-tumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: OMP 59R5; Anti-Human NOTCH2 Recombinant Antibody. CAS No. 1359940-55-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99320. | |
| Taribavirin hydrochloride | Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 40372-00-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10545A. | |
| Tariquidar | Tariquidar (XR9576) is a potent and specific inhibitor of P-glycoprotein (P-gp) with the high affinity (Kd=5.1 nM)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XR9576. CAS No. 206873-63-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10550. | |
| Tariquidar methanesulfonate, hydrate | Tariquidar methanesulfonate, hydrate (XR9576 methanesulfonate, hydrate) is a potent and specific inhibitor of P-glycoprotein (P-gp) with a Kd of 5.1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XR9576 methanesulfonate, hydrate. CAS No. 625375-83-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10550A. | |
| Tarlatamab | Tarlatamab (AMG-757) is a bispecific T-cell engager (BiTE) antibody targeting delta-like ligand 3 (DLL3). DLL3 is a target that is selectively expressed in small-cell lung cancer (SCLC) tumors, but with minimal normal tissue expression. Tarlatamab has the K D s of 0.64 nM and 0.50 nM for human and nonhuman primate (NHP) DLL3, respectively. Tarlatamab has the K D s of 14.9 nM and 12 nM for human and NHP CD3, respectively. Tarlatamab is a first-in-class HLE BiTE immuno-oncology therapy targeting DLL3 and has the potential for SCLC research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG-757. CAS No. 2307488-83-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99575. | |
| Tarloxotinib bromide | Tarloxotinib bromide (TH-4000) is an irreversible EGFR/HER2 inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TH-4000. CAS No. 1636180-98-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17632. | |
| Tartrazine | Tartrazine (Acid Yellow 23; FD&C Yellow No. 5) is an orally active azo acid dye, orange-yellow powder, soluble in water and turns yellow. Tartrazine is mainly used as a synthetic lemon yellow azo dye for food coloring. Tartrazine is the most stable colorant.Tartrazine induces mitochondria-mediated Apoptosis. Tartrazine can cause neurodevelopmental toxicity, cytotoxicity, and genotoxicity [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Yellow 23; FD&C Yellow No. 5. CAS No. 1934-21-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-D0257. | |
| TAS-114 | TAS-114 is an orally active dual dUTPase/dihydropyrimidine dehydrogenase (DPD) inhibitor, can improving the therapeutic efficacy of fluoropyrimidine[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1198221-21-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124062. | |
| TAS-119 | TAS-119 is a potent, selective and orally active Aurora A inhibitor with an IC 50 of 1.0 nM. TAS-119 shows high selectivity for Aurora A over other protein kinases, including Aurora B ( IC 50 of 95 nM). TAS-119 has potent antitumor activites [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1453099-83-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137377. | |
| TAS4464 | TAS4464 is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE) , with an IC 50 of 0.955 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1848959-10-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-128586. | |
| TAS4464 hydrochloride | TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE) , with an IC 50 of 0.955 nM [1]. TAS4464 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1848959-11-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128586A. | |
| Taselisib | Taselisib (GDC-0032) is a potent PI3K inhibitor targets PIK3CA mutations, with K i s of 0.12 nM, 0.29 nM, 0.97 nM, and 9.1 nM for PI3Kδ, PI3Kα, PI3Kγ and PI3Kβ, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0032; RG-7604. CAS No. 1282512-48-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13898. | |
| Tasimelteon | Tasimelteon (BMS-214778) is an orally active and selective dual melatonin receptor agonist (DMRA). Tasimelteon has 2.1-4.4 times greater affinity for the MT2 receptor than for the MT1 receptor. Tasimelteon is a circadian regulator and has the potential for Non-24-Hour Sleep-Wake Disorder (Non-24) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-214778; VEC-162. CAS No. 609799-22-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14803. | |
| TASIN-1 | TASIN-1 is a selective inhibitor of truncated APCTR (adenomatous polyposis coli gene) that exerts cytotoxic effects by inhibiting cholesterol biosynthesis. TASIN-1 specifically targets colorectal cancer (CRC) cells carrying APC truncated mutations, while having no significant toxicity to wild-type APC cells. TASIN-1 exerts cytotoxic effects by targeting Emopamil binding protein (EBP) to inhibit cholesterol biosynthesis, triggering endoplasmic reticulum (ER) stress, reactive oxygen species (ROS) generation, and JNK-mediated apoptosis, and inhibiting Akt survival signaling. TASIN-1 can be used to prevent and intervene in APC mutant colorectal cancer[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 792927-06-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116572A. | |
| TASIN-30 | TASIN-30 is an EBP inhibitor, with EC50 values of 0.097 ?M for EBP competition and 50 ?M for DHCR7 competition, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1678515-93-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164561. | |
| Tasipimidine sulfate | Tasipimidine sulfate is an orally active and selective α2A-adrenoceptor agonist with a p EC 50 of 7.57 against human α2A-adrenoceptor. Tasipimidine sulfate can be used for situational anxiety and fear research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1465908-73-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109075A. | |
| Tasisulam | Tasisulam is a anticancer agent and induces apoptosis via the intrinsic pathway, resulting in cytochrome c release and caspase-dependent cell death. Tasisulam inhibits mitotic progression and induces vascular normalization[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY 573636. CAS No. 519055-62-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14804. | |
| Tasosartan | Tasosartan is a long-acting angiotensin II ( AngII ) receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WAY-ANA 756. CAS No. 145733-36-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-A0250. | |
| Taspine | Taspine is a natural product with anti-inflammatory activity. Taspine suppresses P2X4 receptor activity via PI3K inhibition. Taspine inhibits pro-inflammatory signalling via inhibition of P2X4 receptors in macrophage [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 602-07-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-131502. | |
| Taspoglutide | Taspoglutide is a long-acting glucagon-like peptide 1 ( GLP-1 ) receptor agonist developed for treatment of type 2 diabetes, with an EC 50 value of 0.06 nM. Uses: Scientific research. Group: Peptides. Alternative Names: ITM077; R1583; BIM51077. CAS No. 275371-94-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0165. | |
| Tasquinimod | Tasquinimod is an oral antiangiogenic agent, which has the potential for castration-resistant prostate cancer treatment. Tasquinimod binds to the regulatory Zn 2+ binding domain of HDAC4 with K d of 10-30 nM. Tasquinimod also is a S100A9 inhibitor [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABR-215050. CAS No. 254964-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10528. | |
| TAT-14 | TAT-14 is a 14-mer peptide that acts as Nrf2 activator with an anti-inflammatory effect. TAT-14 has no effect on Nrf2 mRNA expression, but increases Nrf2 protein level due to targeting the Nrf2 binding site on Keap1 [1]. Uses: Scientific research. Group: Peptides. CAS No. 1362661-34-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1328. | |
| Tat-beclin 1 | Tat-beclin 1, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR-1 (GLIPR2). Tat-beclin 1 decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens (including HIV-1) in vitro, and reduces mortality in mice infected with chikungunya (CHIKV) or West Nile virus (WNV)[1]. Uses: Scientific research. Group: Peptides. CAS No. 1423821-88-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P2260. | |
| TAT-CN21 | TatCN21 is a potent and selective inhibitor peptide for the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase, with an IC50 of 77 nM. TatCN21 can be utilized in research on ischemia and neurodegenerative diseases[1]. Uses: Scientific research. Group: Peptides. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P10638. | |
| TAT-cyclo-CLLFVY | TAT-cyclo-CLLFVY is a cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. TAT-cyclo-CLLFVY disrupts HIF-1α/HIF-1β protein-protein interaction with an IC 50 of 1.3 μM [1]. Uses: Scientific research. Group: Peptides. CAS No. 1446322-66-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1420. | |
| TAT-HA2 Fusion Peptide | TAT-HA2 Fusion Peptide is a peptide-based delivery agent that combines the pH-sensitive HA2 fusion peptide from Influenza and the cell-penetrating peptide TAT from HIV. TAT-HA2 Fusion Peptide is a transactivator of transcription and hemaglutanin for endosomal release. TAT-HA2 Fusion Peptide enhances cellular uptake of macromolecules[1]. Uses: Scientific research. Group: Peptides. CAS No. 923954-79-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4108. | |
| Taurine | Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Aminoethanesulfonic acid. CAS No. 107-35-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0351. | |
| Tauro-α-muricholic acid sodium | Tauro-α-muricholic acid (T-α-MCA) sodium is a FXR ( Farnesoid X receptor ) antagonist ( IC 50 =28μM). Tauro-α-muricholic acid sodium is also a endogenous metabolite that can be found in cecal [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: T-α-MCA sodium. CAS No. 2260905-08-4. Pack Sizes: 1 mg. Product ID: HY-133890A. | |
| Tauro-β-muricholic acid sodium | Tauro-β-muricholic Acid sodium (T-βMCA sodium), a endogenous metabolite, is a competitive and reversible farnesoid X receptor (FXR) antagonist, with an IC 50 of 40 μM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T-βMCA sodium. CAS No. 145022-92-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135103. | |
| Taurochenodeoxycholic acid | Taurochenodeoxycholic acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 12-Deoxycholyltaurine. CAS No. 516-35-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N2027. | |
| Taurochenodeoxycholic acid sodium | Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and immune regulation properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 12-Deoxycholyltaurine sodium. CAS No. 6009-98-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N1429. | |
| Taurochenodeoxycholic acid (sodium) (Standard) | Taurochenodeoxycholic acid (sodium) (Standard) is the analytical standard of Taurochenodeoxycholic acid (sodium). This product is intended for research and analytical applications. Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and immune regulation properties [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 6009-98-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1429R. | |
| Taurocholic acid | Taurocholic acid (N-Choloyltaurine) has marked bioactive effects such as an inhibitory potential against hepatic artery ligation induced biliary damage by upregulation of VEGF-A expression. Taurocholic acid has immunoregulation effect [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Taurocholic Acid. CAS No. 81-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1788. | |
| Taurocholic acid-d4 | Taurocholic acid-d 4 is deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: N-Choloyltaurine-d4. CAS No. 252030-90-3. Pack Sizes: 100 μg (192.41 μM * 1 mL in Methanol); 1 mg; 5 mg. Product ID: HY-B1788S1. | |
| Taurocholic acid-d4 sodium | Taurocholic acid-d 4 (sodium) is the deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: N-Choloyltaurine-d4 sodium. CAS No. 2410279-93-3. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1788S. | |
| Taurocholic acid sodium | Taurocholic acid sodium (Sodium taurocholate) has marked bioactive effects such as an inhibitory potential against hepatic artery ligation induced biliary damage by upregulation of VEGF-A expression. Taurocholic acid sodium has immunoregulation effect [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium taurocholate; N-Choloyltaurine sodium. CAS No. 145-42-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N0545. | |
| Taurocholic acid sodium salt hydrate | Taurocholic acid sodium salt hydrate (Sodium taurocholate hydrate) is a bile acid involved in the emulsification of fats. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium taurocholate hydrate; N-Choloyltaurine sodium salt hydrate. CAS No. 345909-26-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1131. | |
| Taurodeoxycholate sodium salt | Taurodeoxycholate sodium salt is a bile salt-related anionic detergent. Taurodeoxycholate sodium salt is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholate sodium salt is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) exhibits anti-inflammatory and neuroprotective effects [1] [2] [3] [9] [10]. Uses: Scientific research. Group: Natural products. CAS No. 1180-95-6. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-128853. | |
| Taurodeoxycholic acid | Taurodeoxycholate sodium salt is a bile salt-related anionic detergent. Taurodeoxycholic acid is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholic acid is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholic acid (TDCA) exhibits anti-inflammatory and neuroprotective effects [1] [2] [3] [9] [10]. Uses: Scientific research. Group: Natural products. CAS No. 516-50-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B1899. | |
| Taurodeoxycholic acid sodium hydrate | Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a bile acid, is an amphiphilic surfactant molecule synthesized from cholesterol in the liver. Taurodeoxycholic acid sodium hydrate activates the S1PR2 pathway in addition to the TGR5 pathway [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium taurodeoxycholate monohydrate. CAS No. 110026-03-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1899A. | |
| Taurohyodeoxycholic acid | Taurohyodeoxycholic acid is the tauroconjugated form of Hyodeoxycholic acid (HDCA, a dihydroxylated natural bile acid). Taurohyodeoxycholic acid induces a biliary phospholipid secretion and suggests a hepatoprotective potential. Taurohyodeoxycholic acid also can promote gallstone dissolution [1] [1]. Uses: Scientific research. Group: Natural products. CAS No. 2958-4-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114360. | |
| Taurohyodeoxycholic acid sodium | Taurohyodeoxycholic acid (THDCA) sodium is the taurine-conjugated form of the secondary bile acid hyodeoxycholic acid. Taurohyodeoxycholic acid can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 38411-85-7. Pack Sizes: 50 mg; 100 mg. Product ID: HY-114360A. | |
| Taurolidine | Taurolidine is a potent antimicrobial and anticancer agent. Taurolidine inhibits cell proliferation. Taurolidine induces apoptosis and autophagy. Taurolidine rescues mice from sepsis-associated lethality [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19388-87-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W011522. | |
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