MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Tolazamide | Tolazamide is an oral hypoglycemic agent used in the study of type 2 diabetes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: U-17835. CAS No. 1156-19-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0920. |  |
| Tolazoline | Tolazoline(Imidaline) is a non-selective competitive α-adrenergic receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Imidaline; NSC35110. CAS No. 59-98-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-A0066. | |
| Tolazoline hydrochloride | Tolazoline (Imidaline) hydrochloride is an alpha-adrenergic receptor inhibitor. Uses: Scientific research. Group: Natural products. Alternative Names: Imidaline hydrochloride; NSC35110 hydrochloride. CAS No. 59-97-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-A0066A. | |
| Tolbutamide | Tolbutamide is an orally active K ATP inhibitor. Tolbutamide inhibits cell proliferation, stimulates exocytosis of glucagon and reduces fetal lethality of mice. Tolbutamide can be used in the research of diabete [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 64-77-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0401. | |
| Tolbutamide (Standard) | Tolbutamide (Standard) is the analytical standard of Tolbutamide. This product is intended for research and analytical applications. Tolbutamide is an orally active K ATP inhibitor. Tolbutamide inhibits cell proliferation, stimulates exocytosis of glucagon and reduces fetal lethality of mice. Tolbutamide can be used in the research of diabete [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 64-77-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B0401R. | |
| Tolcapone | Tolcapone (Ro 40-7592) is a selective, orally active and powerful mixed (peripheral and central) COMT inhibitor with an IC 50 of 773?nM in the liver [1]. Tolcapone is also a potent inhibitor of α-syn and Aβ42 oligomerization and fibrillogenesis [2]. Tolcapone induces oxidative stress leading to apoptosis and inhibition of tumor growth in neuroblastoma [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 40-7592. CAS No. 134308-13-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17406. | |
| Tolclofos-methyl | Tolclofos-methyl is a broad-spectrum aromatic hydrocarbon fungicide that is used as a see treatment for protection against soil-borne and seed borne fungal pathogens that caused seed decay and seedling blights. Uses: Scientific research. Group: Signaling pathways. CAS No. 57018-04-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B2053. | |
| Tolclofos-methyl (Standard) | Tolclofos-methyl (Standard) is the analytical standard of Tolclofos-methyl. This product is intended for research and analytical applications. Uses: Scientific research. Group: Signaling pathways. CAS No. 57018-04-9. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B2053R. | |
| Tolebrutinib | Tolebrutinib (SAR442168) is a potent, selective, orally active and brain-penetrant inhibitor of Bruton tyrosine kinase (BTK) , with IC 50 s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively. Tolebrutinib exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAR442168; PRN2246. CAS No. 1971920-73-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109192. | |
| Tolfenamic Acid | Tolfenamic Acid (GEA 6414) is a non-steroidal anti-inflammatory and anti-cancer agent, selectively inhibits COX-2 , with an IC 50 of 13.49 μM (3.53 μg/mL) in LPS-treated (COX-2) canine DH82 monocyte/macrophage cells, but shows no effect on COX-1. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GEA 6414. CAS No. 13710-19-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B0335. | |
| Tolfenamic Acid (Standard) | Tolfenamic Acid (Standard) is the analytical standard of Tolfenamic Acid. This product is intended for research and analytical applications. Tolfenamic Acid (GEA 6414) is a non-steroidal anti-inflammatory and anti-cancer agent, selectively inhibits COX-2 , with an IC 50 of 13.49 μM (3.53 μg/mL) in LPS-treated (COX-2) canine DH82 monocyte/macrophage cells, but shows no effect on COX-1. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GEA 6414 (Standard). CAS No. 13710-19-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0335R. | |
| Tolfenpyrad | Tolfenpyrad is an insecticide approved for marketing in Japan in 2002. Uses: Scientific research. Group: Signaling pathways. CAS No. 129558-76-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17516. | |
| Tolinapant | Tolinapant (ASTX660) is an orally bioavailable dual antagonist of cellular inhibitor of apoptosis protein ( cIAP ) and X-linked inhibitor of apoptosis protein ( XIAP ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASTX660. CAS No. 1799328-86-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109565. | |
| Tolmetin | Tolmetin is an orally active and potent COX inhibitor with IC 50 s of 0.35 μM and 0.82 μM human COX-1 and COX-2, respectively. Tolmetin is a non-steroidal anti-inflammatory drug (NSAID) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 26171-23-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-B1799. | |
| Tolmetin sodium dihydrate | Tolmetin sodium dihydrate is an orally active and potent COX inhibitor with IC 50 s of 0.35 μM and 0.82 μM human COX-1 and COX-2, respectively. Tolmetin sodium dihydrate is a non-steroidal anti-inflammatory drug (NSAID) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 64490-92-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1489. | |
| Tolnaftate | Tolnaftate (NP-27) is a synthetic thiocarbamate used as an anti-fungal agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NP-27. CAS No. 2398-96-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0370. | |
| Toloxatone | Toloxatone (MD 69276) is a reversible monoamine oxidase A ( MAO A ) inhibitor [1]. Antidepressant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MD 69276. CAS No. 29218-27-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14196. | |
| Tolperisone hydrochloride | Tolperisone hydrochloride is a centrally acting muscle relaxant studied in neurological disorders causing pathological rhabdomyosclerosis (pyramidal tract injury, multiple sclerosis, myelopathy, encephalomyelitis), spastic paralysis, and other muscle dystonia-related Encephalopathy. Tolperisone hydrochloride also has antiviral activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3644-61-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B1139. | |
| Tolterodine | Tolterodine(PNU-200583) is a potent muscarinic receptor antagonists that show selectivity for the urinary bladder over salivary glands in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-(+)-Tolterodine; (+)-Tolterodine; (R)-Tolterodine; PNU-200583. CAS No. 124937-51-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0024. | |
| Tolterodine-d14 hydrochloride | Tolterodine-d 14 (hydrochloride) is the deuterium labeled Tolterodine hydrochloride[1]. Tolterodine hydrochloride is a potent muscarinic receptor antagonist[2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (R)-(+)-Tolterodine-d14 hydrochloride; (+)-Tolterodine-d14 hydrochloride; (R)-Tolterodine-d14 hydrochloride; PNU-200583-d14 hydrochloride. CAS No. 1217645-16-3. Pack Sizes: 1 mg. Product ID: HY-A0024S. | |
| Tolterodine tartrate | Tolterodine Tartrate (Kabi-2234; PNU-200583E) is a potent muscarinic receptor antagonist and shows selectivity for the urinary bladder over salivary glands in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Kabi-2234; PNU-200583E. CAS No. 124937-52-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-90010. | |
| Toltrazuril | Toltrazuril (BAY-i 9142) is an antiprotozoal agent that acts upon Coccidia parasites. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-i 9142. CAS No. 69004-03-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0175. | |
| Toltrazuril (sulfone) | Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril (HY-B0175), with antiprotozoal activity. Toltrazuril sulfone is a triazine anticoccidial that is developed to prevent coccidiosis in poultry[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ponazuril. CAS No. 69004-04-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-17008. | |
| Tolvaptan | Tolvaptan is a selective, competitive and orally active vasopressin receptor 2 ( V 2 R ) antagonist with an IC 50 of 1.28 μM for the inhibition of arginine vasopressin (AVP)-induced platelet aggregation. Tolvaptan induces cell apoposis and affects cell cycle. Tolvaptan can be used for the research of hyponatremia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC-41061. CAS No. 150683-30-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17000. | |
| Tomaralimab | Tomaralimab (OPN-305) is a humanised anti-TLR2 IgG4 monoclonal antibody. Tomaralimab has the potential for the research of Myelodysplastic Syndromes (MDS) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: OPN-305. CAS No. 1449294-76-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99555. | |
| Tomatidine | Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling [1]. Tomatidine activates autophagy either in mammal cells or C elegans [2]. Uses: Scientific research. Group: Natural products. CAS No. 77-59-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2149. | |
| Tomatidine hydrochloride | Tomatidine hydrochloride acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling [1]. Tomatidine hydrochloride activates autophagy either in mammal cells or C elegans [2]. Uses: Scientific research. Group: Natural products. CAS No. 6192-62-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2149A. | |
| Tomatine | Tomatine is a glycoalkaloid, found in the tomato plant ( Lycopersicon esculentum Mill.). Tomatine elicits neurotoxicity in RIP1 kinase and caspase-independent manner. Tomatine promotes the upregulation of nuclear apoptosis inducing factor (AIF) in neuroblastoma cells. Tomatine also inhibits 20S proteasome activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: α-Tomatine; Lycopersicin; Tomatin. CAS No. 17406-45-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N2166. | |
| Tominersen sodium | Tominersen sodium is a second-generation 2?-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen improves survival and reduces brain atrophy in mice. Tominersen sodium can be used for the research of Huntingtons disease (HD)[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG6042 sodium; IONIS-HTTRx sodium. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132579A. | |
| Tomivosertib | Tomivosertib (eFT508) is a potent, highly selective, and orally active MNK1 and MNK2 inhibitor, with IC 50 s of 1-2 nM against both isoforms. Tomivosertib (eFT508) treatment leads to a dose-dependent reduction in eIF4E phosphorylation at serine 209 (IC 50 =2-16 nM) in tumor cell lines [1]. Tomivosertib (eFT508) also dramatically downregulates PD-L1 protein abundance [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: eFT508. CAS No. 1849590-01-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100022. | |
| Tonabersat | Tonabersat (SB-220453) is a gap-junction modulator. Tonabersat prevents inflammatory damage in the central nervous system [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-220453. CAS No. 175013-84-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15204. | |
| Toosendanin | Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 58812-37-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0263. | |
| Topiramate | Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels , increases in potassium conductance, and inhibition of carbonic anhydrase [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: McN 4853; RWJ 17021. CAS No. 97240-79-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0122. | |
| Topiroxostat | Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC 50 value of 5.3 nM and a K i value of 5.7 nM. Topiroxostat exhibits weak CYP3A4 -inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FYX-051. CAS No. 577778-58-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14874. | |
| Topoisomerase II inhibitor 14 | Topoisomerase II inhibitor 14 (compound 2f) is a potent inhibtor of Topoisomerase II, with anticancer activity. Topoisomerase II inhibitor 14 induces apoptosis, and arrests cell cycle at S phase. Topoisomerase II inhibitor 14 exhibits antioxidant effect and decreases the level of GSH, MDA, and NO [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 305343-00-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W278582. | |
| Topotecan | Topotecan (SKF 104864A; NSC 609669) is an orally active and potent Topoisomerase I inhibitor. Topotecan induces cell cycle arrest in G0/G1 and S phases and promotes apoptosis. Topotecan shows anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF 104864A; NSC 609669. CAS No. 123948-87-8. Pack Sizes: 1 mg. Product ID: HY-13768. | |
| Topotecan hydrochloride | Topotecan Hydrochloride (SKF 104864A Hydrochloride) is a Topoisomerase I inhibitor with potent antineoplastic activities. Uses: Scientific research. Group: Natural products. Alternative Names: SKF 104864A hydrochloride; NSC 609669 hydrochloride. CAS No. 119413-54-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13768A. | |
| TO-PRO-3 iodide | TO-PRO-3 iodide is a highly efficient blue fluorescent dye that can stain cytoplasm as a cell tracer. Uses: Scientific research. Group: Fluorescent dye. CAS No. 157199-63-8. Pack Sizes: 671 μg (5 mM * 200 μL in DMSO). Product ID: HY-117070. | |
| TOPS | TOPS is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 40567-80-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15933. | |
| Torcetrapib | Torcetrapib (CP-529414) is a selective, potent cholesteryl ester transfer protein ( CETP ) inhibitor. A typical inhibition curve for whole human plasma, having a CETP concentration of 37 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-529414. CAS No. 262352-17-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-12089. | |
| Toreforant | Toreforant is a potent and selective histamine H 4 receptor ( H4R ) antagonist, with a K i at the human receptor of 8.4 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-38518168. CAS No. 952494-46-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16756. | |
| Toremifene | Toremifene (Z-Toremifene) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC 50 of 0.07 μM and 2.6 μM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-Toremifene; NK 622 free base; FC-1157a free base. CAS No. 89778-26-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg. Product ID: HY-B0005A. | |
| Toremifene citrate | Toremifene citrate (Z-Toremifene citrate) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC 50 of 0.07 μM and 2.6 μM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-Toremifene citrate; NK 622; FC-1157a. CAS No. 89778-27-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0005. | |
| Torin 1 | Torin 1 is a potent inhibitor of mTOR with an IC 50 of 3 nM. Torin 1 inhibits both mTORC1 / 2 complexes with IC 50 values between 2 and 10 nM. Torin 1 is an effective inducer of autophagy. Uses: Scientific research. Group: Signaling pathways. CAS No. 1222998-36-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13003. | |
| Torin 2 | Torin 2 is an mTOR inhibitor with EC50 of 0.25 nM for inhibiting cellular mTOR activity, and exhibits 800-fold selectivity over PI3K (EC50: 200 nM). Torin 2 also inhibits DNA-PK with an IC50 of 0.5 nM in the cell free assay. Torin 2 can suppress both mTORC1 and mTORC2. Uses: Scientific research. Group: Signaling pathways. CAS No. 1223001-51-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13002. | |
| Toripalimab | Toripalimab is the first domestic anti-tumor PD-1 antibody in China. Toripalimab is a selective, recombinant, humanized monoclonal antibody against PD-1. Toripalimab is able to bind to PD-1 and block the interaction with its ligands. Toripalimab has exhibited primary anti-tumor effects in tumors such as melanoma, lung cancer, digestive tract tumors, hepatobiliary and pancreatic tumors, neuroendocrine neoplasms, nasopharyngeal carcinoma and urothelial carcinoma [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1924598-82-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P9978. | |
| Torkinib | Torkinib (PP 242) is a selective and ATP-competitive mTOR inhibitor with an IC50 of 8 nM[1]. PP242 inhibits both mTORC1 and mTORC2 with IC50s of 30 nM and 58 nM, respectively[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PP 242. CAS No. 1092351-67-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10474. | |
| Torsemide | Torsemide (Torasemide) is an orally active loop diuretic. Torsemide has anti-aldosterone and vasodilatory effects. Torsemide also can be used for the research of heart failure, renal disease and hepatic cirrhosis [1] [1] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Torasemide. CAS No. 56211-40-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 100 mg. Product ID: HY-B0247. | |
| Torudokimab | Torudokimab is a humanized antibody expressed in CHO, targeting IL-33. Torudokimab has a huIgG4SP type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145.22 kDa. The isotype control for Torudokimab can refer to Human IgG4 kappa, Isotype Control (HY-P99003). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2241728-76-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990669. | |
| Tosedostat | Tosedostat (CHR-2797) is an orally active aminopeptidase inhibitor. CHR-2797 exerts antiproliferative effects against a range of tumor cell lines [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CHR-2797. CAS No. 238750-77-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14807. | |
| Tositumomab | Tositumomab is a murine IgG2a lambda monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human CD20 Recombinant Antibody. CAS No. 192391-48-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99326. | |
| Tos-PEG3 | Tos-PEG3 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 77544-68-4. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-23408. | |
| Tos-PEG3-CH2COOtBu | Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1530778-24-5. Pack Sizes: 100 mg; 1 g; 5 g; 10 g. Product ID: HY-45018. | |
| Tosufloxacin tosylate hydrate | Tosufloxacin tosylate hydrate (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: A-61827 tosylate hydrate; T-3262. CAS No. 1400591-39-0. Pack Sizes: 10 mM * 1 mL; 200 mg; 1 g; 5 g; 10 g. Product ID: HY-B1802A. | |
| (+)-Totarol | (+)-Totarol is a diterpenoid compound isolated from Podocarpus spp. (+)-Totarol is a potent antioxidant and antibacterial agent [1]. Uses: Scientific research. Group: Natural products. CAS No. 511-15-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N1136. | |
| Tovorafenib | Tovorafenib (TAK-580, MLN 2480) is an orally active and selective inhibitor of pan-Raf kinase. Tovorafenib can be used for the study of glioma [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-580; MLN 2480; BIIB-024. CAS No. 1096708-71-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15246. | |
| Toxoflavin | Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex , also acts as an inhibitor of KDM4A , with antitumor and antibiotic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Xanthothricin; Toxoflavine; PKF-118-310. CAS No. 84-82-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-100760. | |
| Toyocamycin | Toyocamycin (Vengicide) is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin affects IRE1?-XBP1 pathway, and inhibits XBP1 mRNA cleavage with an IC50 value of 80 nM with affecting IRE1? auto-phosphorylation. Toyocamycin specifically inhibits CDK9 with an IC50 value of 79 nM[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: Vengicide. CAS No. 606-58-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103248. | |
| Tozadenant | Tozadenant is an adenosine A 2A receptor antagonist, with K i of 11.5 nM on human A 2A and 6 nM on rhesus A 2A. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SYN115. CAS No. 870070-55-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10995. | |
| Tozasertib | Tozasertib (VX 680; MK-0457) is an inhibitor of Aurora A/B/C kinases with K i s of 0.6, 18, 4.6 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX 680; MK-0457. CAS No. 639089-54-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-10161. | |
| Tozorakimab | Tozorakimab (MEDI-3506) is a human immunoglobulin G1 monoclonal antibody targeting interleukin-33. Tozorakimab reduces inflammation and epithelial dysfunction. Tozorakimab can be used to research chronic obstructive pulmonary disease [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI-3506. CAS No. 2376858-66-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99550. | |
| TP-020 | TP-020 (MGAT2-IN-1) is an orally active inhibitor of monoacylglycerol acyltransferase (MGAT2) with IC 50 of 7.8 and 2.4 nM for human and mouse MGAT2, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGAT2-IN-1. CAS No. 1800025-30-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101857. | |
| TP-021 | TP-021 (BCL6-IN-8c) is a potent and orally active B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor with an IC 50 of 0.10 μM in cell-free enzyme-linked immunosorbent assay [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BCL6-IN-8c. CAS No. 2130878-25-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119402. | |
| TP-024 | TP-024 (FTBMT) is a selective GPR52 agonist with an EC 50 of 75 nM [1]. TP-024 has antipsychotic and procognitive properties [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTBMT. CAS No. 1358575-02-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101787. | |
| TP-040 | TP-040 (O-GlcNAcase-IN-1) is a potent and novel OGA inhibitor with an IC 50 value of 46 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: O-GlcNAcase-IN-1. CAS No. 2757254-99-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131979. | |
| TP0427736 hydrochloride | TP0427736 hydrochloride is a potent inhibitor of ALK5 kinase activity with an IC 50 of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC 50 =836 nM). TP0427736 hydrochloride also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with an IC 50 value of 8.68 nM. TP0427736 hydrochloride can be used for the research of androgenic alopecia (AGA) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2459963-17-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118528A. | |
| TP0463518 | TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases ( PHD s) inhibitor with a K i value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1 / PHD3 with IC 50 s of 18 and 63 nM as well as monkey PHD2 with an IC 50 value of 22 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1558021-37-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112144. | |
| TP-060 | Glucosylceramide synthase-IN-1 (T-036) a potent, brain-penetrant and orally active glucosylceramide synthase (GCS) inhibitor with IC 50 s of 31 nM and 51 nM for human GCS and mouse GCS, respectively. Glucosylceramide synthase-IN-1 can be used for Gaucher's disease research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glucosylceramide synthase-IN-1. CAS No. 2601393-20-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144266. | |
| TP-064 | TP-064 is a potent and selective proteinarginine methyltransferase 4 (PRMT4; CARM1) inhibitor ( IC 50 <10 nM). TP-064 inhibits dimethylation of BAF155 ( IC 50 of 340 nM) and MED12 ( IC 50 of 43 nM). TP-064 is inactive against the other family members except for PRMT6 (IC 50 of 1.3 μM). TP-064 has anticancer activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2080306-20-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114965. | |
| TP-1287 | TP-1287, a prodrug of Alvocidib (HY-10005), is an orally active CDK9 inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2044686-42-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153260. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.