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Thalidomide
Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a K d of ?250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide can work as molecular glue to potentiate substrate. Uses: Scientific research. Group: Signaling pathways. CAS No. 50-35-1. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-14658.
Thalidomide 4-fluoride
Thalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1 (HY-129966)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cereblon ligand 4; E3 ligase Ligand 4. CAS No. 835616-60-9. Pack Sizes: 1 g; 5 g. Product ID: HY-41547.
Thalidomide-4-O-C4-NH2 hydrochloride
Thalidomide-4-O-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide (HY-14658) based cereblon ligand and a linker used in PROTAC technology. Uses: Scientific research. Group: Signaling pathways. CAS No. 2376990-29-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-130948B.
Thalidomide-5-OH
Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTACs[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 64567-60-8. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g; 25 g. Product ID: HY-23095.
Thalidomide-5-PEG3-NH2 hydrochloride
Thalidomide-5-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2761385-81-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-138786A.
Thalidomide-O-amido-PEG2-C2-NH2 TFA
Thalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cereblon Ligand-Linker Conjugates 10 TFA; E3 Ligase Ligand-Linker Conjugates 24 TFA. CAS No. 1957235-75-4. Pack Sizes: 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-112617A.
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2245697-84-9. Pack Sizes: 25 mg; 100 mg. Product ID: HY-107440A.
Thalidomide-O-amido-PEG3-C2-NH2 TFA
Thalidomide-O-amido-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cereblon Ligand-Linker Conjugates 3 TFA; E3 ligase Ligand-Linker Conjugates 14 TFA. CAS No. 1957236-21-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103611.
Thalidomide-piperazine hydrochloride
Thalidomide-piperazine hydrochloride has the potential for the research of leprosy and multiple myeloma. Thalidomide-piperazine hydrochloride used as a tool in developmental biology leads to important discoveries in the biochemical pathways of limb development [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2228029-82-9. Pack Sizes: 25 mg; 50 mg. Product ID: HY-132971.
Thalidomide-Piperazine-Piperidine hydrochloride
Thalidomide-Piperazine-Piperidine hydrochloride is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-Piperazine-Piperidine hydrochloride incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2599846-44-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138783A.
Thalidomide-pyrrolidine hydrochloride
Thalidomide-pyrrolidine hydrochloride (compound 18) is an E3 ligase ligand , and can be used for synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2616553-35-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W248665A.
THAL-SNS-032
THAL-SNS-032 is a selective CDK9 degrader PROTAC consisting of a CDK-binding SNS-032 ligand linked to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon (CRBN)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2139287-33-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123937.
THAM
THAM (Tris) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. THAM is an effective amine compound for pH control in the physiological range [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tris; Tris(hydroxymethyl)aminomethane. CAS No. 77-86-1. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-D0227.
THAM hydrochloride
THAM hydrochloride (Tris HCl) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. THAM hydrochloride is an effective amine compound for pH control in the physiological range [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tris HCl; Tris(hydroxymethyl)aminomethane hydrochloride. CAS No. 1185-53-1. Pack Sizes: 10 g; 25 g. Product ID: HY-D0227A.
Thanatin TFA
Thanatin TFA is an inducible cationic antimicrobial peptide. Thanatin TFA s a pathogen-inducible single-disulfide-bond-containing ?-hairpin AMP. Thanatin TFA displays broad-spectrum activity against both Gram-negative and Gram-positive bacteria as well as against various species of fungi with MICs of 0.3-40 μM, 0.6-40 μM and 0.6-20 μM, respectively. Thanatin TFA has the property of competitive replacement of divalent cations from bacterial outer membrane (OM), leading to OM disruption[1][2]. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5601A.
Thapsigargin
Thapsigargin, an endoplasmic reticulum (ER) stress inducer, is an inhibitor of microsomal Ca 2+ -ATPase. Thapsigargin efficiently inhibits coronavirus (HCoV-229E, MERS-CoV, SARS-CoV-2) replication in different cell types [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 67526-95-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13433.
Thaumatins
Thaumatins is a protein, which can be purified from the fruit of Thaumatococcus daniellii Benth. Thaumatins is 100,000 times sweeter than sucrose on a molar basis [1]. Uses: Scientific research. Group: Natural products. CAS No. 53850-34-3. Pack Sizes: 100 mg. Product ID: HY-W540600.
Theaflavin
Theaflavin is a suitable natural inhibitor against influenza A ( H1N1 ) neuraminidase. Uses: Scientific research. Group: Natural products. CAS No. 4670-5-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0243.
Theaflavin 3,3'-digallate
Theaflavin 3,3'-digallate (TF-3) is a potent Zika virus (ZIKV) protease inhibitor with an IC 50 of 2.3 μM. Theaflavin 3,3'-digallat directly binds to ZIKVpro ( K d =8.86 μM) and inhibits ZIKV replication. Theaflavin 3,3'-digallat inhibits the activity of gp41 and NS2B-3 protease and has antiviral activity against HSV and HIV-1 [1]. Theaflavin 3,3'-digallate, the typical pigment in black tea, is a potent antitumor agent [2]. Uses: Scientific research. Group: Natural products. Alternative Names: TF-3; ZP10. CAS No. 30462-35-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N1992.
Theaflavin-3-gallate
Theaflavin-3-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3-gallate reacts directly with reduced glutathione (GSH) in a time- and concentration-dependent manner [1]. Uses: Scientific research. Group: Natural products. CAS No. 30462-34-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0245.
Theobromine
Theobromine is a methylxanthine found in cacao beans which can inhibit adenosine receptor A1 ( AR1 ) signaling. Uses: Scientific research. Group: Natural products. Alternative Names: 3,7-Dimethylxanthine. CAS No. 83-67-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N0138.
Theodrenaline hydrochloride
Theodrenaline hydrochloride is a cardiac stimulant, also acts as an anti-hypotensive agent together with Cafedrine. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)?-Theodrenaline hydrochloride. CAS No. 2572-61-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00344A.
Theophylline
Theophylline (1,3-Dimethylxanthine) is a potent phosphodiesterase (PDE) inhibitor, adenosine receptor antagonist, and histone deacetylase (HDAC) activator. Theophylline (1,3-Dimethylxanthine) inhibits PDE3 activity to relax airway smooth muscle. Theophylline (1,3-Dimethylxanthine) has anti-inflammatory activity by increase IL-10 and inhibit NF-κB into the nucleus. Theophylline (1,3-Dimethylxanthine) induces apoptosis. Theophylline (1,3-Dimethylxanthine) can be used for asthma and chronic obstructive pulmonary disease (COPD) research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: 1,3-Dimethylxanthine; Theo-24. CAS No. 58-55-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-B0809.
Theophylline (Standard)
Theophylline (Standard) is the analytical standard of Theophylline. This product is intended for research and analytical applications. Theophylline (1,3-Dimethylxanthine) is a potent phosphodiesterase (PDE) inhibitor, adenosine receptor antagonist, and histone deacetylase (HDAC) activator. Theophylline (1,3-Dimethylxanthine) inhibits PDE3 activity to relax airway smooth muscle. Theophylline (1,3-Dimethylxanthine) has anti-inflammatory activity by increase IL-10 and inhibit NF-κB into the nucleus. Theophylline (1,3-Dimethylxanthine) induces apoptosis. Theophylline (1,3-Dimethylxanthine) can be used for asthma and chronic obstructive pulmonary disease (COPD) research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: 1,3-Dimethylxanthine(Standard); Theo-24 (Standard). CAS No. 58-55-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0809R.
Theralizumab
Theralizumab (TGN1412) is a humanized lgG4 superagonistic anti- CD28 monoclonal antibody that directly stimulates T cells. Theralizumab can cause cytokine release syndrome (CRS). Theralizumab can be used for the research of rheumatoid arthritis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TGN1412. CAS No. 906068-56-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9975.
Thermolysin, Bacillus thermoproteolyticus rokko
Thermolysin, Bacillus thermoproteolyticus rokko (EC 3.4.24.27) (TML) is a thermostable neutral metalloproteinase enzyme secreted by the Gram-positive bacteria Bacillus thermoproteolyticus. Thermolysin catalyzes the hydrolysis of peptide bonds containing hydrophobic residues[1].Optimal pH: 8.0. Considerably stable from pH 5 to 9.5.Optimal temperature : 70 °C. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 3.4.24.27; TML. CAS No. 9073-78-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1748.
Thevetin A
Thevetin A is a thevetia cardiac glycoside. Thevetin A can be isolated from the methanol extract of the seeds of Cascabela thevetioides [1]. Uses: Scientific research. Group: Natural products. CAS No. 37933-66-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W671746.
Thiabendazole
Thiabendazole is an orally available benzimidazole fungicide with repellent and anticancer activities. Thiabendazole can result in developmental malformations. Thiabendazole can be used for modeling [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tiabendazole; 2-(4-Thiazolyl)benzimidazole. CAS No. 148-79-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0263.
Thiacetazone
Thiacetazone (Thioacetazone) is a thiourea-containing antitubercular agent and is an orally active antibiotic. Thiacetazone has antibacterial action, which inhibits growth of Mycobacterium tuberculosis H37Rv with a MIC value of 0.1 μg/mL [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Thioacetazone; Amithiozone. CAS No. 104-06-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1526.
Thiacloprid
Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables [1]. Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 111988-49-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1953.
Thialysine hydrochloride
Thialysine (hydrochloride) is a cysteine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 4099-35-8. Pack Sizes: 250 mg. Product ID: HY-122526.
Thiamet G
Thiamet G is a potent and selective inhibitor of O-GlcNAcase (OGA), which acts to remove O-GlcNAc from modified proteins, with Ki of 20 nM for human OGA. Uses: Scientific research. Group: Signaling pathways. CAS No. 1009816-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12588.
Thiamethoxam
Thiamethoxam is a broad spectrum neonicotinoid insecticide [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 153719-23-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0833.
Thiamethoxam (Standard)
Thiamethoxam (Standard) is the analytical standard of Thiamethoxam. This product is intended for research and analytical applications. Thiamethoxam is a broad spectrum neonicotinoid insecticide [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 153719-23-4. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0833R.
Thiamine hydrochloride
Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.Thiamine hydrochloride activates NrF-2/HO-1 and inhibits TLR4 , NF-κB. Thiamine hydrochloride has neuroprotective and anti-inflammatory effects. Thiamine hydrochloride can be used in the studys of diabetic complications, neurological diseases, cancers, and colitis [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. Alternative Names: Thiamine chloride hydrochloride; Vitamin B1 hydrochloride. CAS No. 67-03-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-N0680.
Thiamine nitrate
Thiamine nitrate is an essential vitamin which can enhance normal neuronal actives. Uses: Scientific research. Group: Natural products. Alternative Names: Vitamin B1 nitrate. CAS No. 532-43-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B2223.
Thiamine pyrophosphate
Thiamine pyrophosphate is the coenzyme form of Vitamin B1, and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex. Thiamine pyrophosphate is necessary for oxidative phosphorylation and the pentose phosphate pathway by acting as a cofactor for α-ketoacid dehydrogenases [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 154-87-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-113076.
Thiamphenicol
Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative , Gram-positive aerobic and anaerobic bacteria ) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Thiophenicol; Dextrosulphenidol. CAS No. 15318-45-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0479.
Thiamphenicol glycinate hydrochloride
Thiamphenicol glycinate hydrochloride is a broad-spectrum antibacterial agent that can be used for respiratory tract infections research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2611-61-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-132282.
Thianthrene
Thianthrene, a sulfur-containing heterocyclic compound, is a derivative of dithiin. Thianthrene can be used in the research of dermal infections, in which it interferes with enzyme and nucleic acid function [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 92-85-3. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W014120.
Thiarabine
Thiarabine (OSI-7836) shows potent anti-tumor activity and inhibition of DNA synthesis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OSI-7836. CAS No. 26599-17-7. Pack Sizes: 1 mg. Product ID: HY-16496.
Thiazole Orange
Thiazole Orange is an asymmetric anthocyanin dye that can be coupled with oligonucleotides (ONs) to prepare fluorescent hybridization probes. Thiazole Orange has been widely used in biomolecular detection and staining of DNA/ RNA in gels and can be used for reticulocyte analysis. Thiazole orange generates a significant fluorescence enhancement and high quantum yield when it binds with nucleic acids, especially RNA. Thiazole orange can permeate living cell membranes. Thiazole orange can use UV light for detection, but can also be detected with blue light. The excitation and emission of Thiazole orange are λ ex = 510 nm (488 nm and 470 nm also show strong excitation) and λ em = 527 nm, respectively [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 107091-89-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-D0150.
Thiazolidine
Thiazolidine is a five-membered heterocyclic compound containing sulfur and nitrogen heteroatoms. Thiazolidine is an important intermediate in organic synthesis. Thiazolidine derivatives possess diverse bioactivities, such as anti-tumor, antibacterial and insecticidal activities, and the capacity to reduce blood glucose levels [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 504-78-9. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-I0144.
Thiazolyl Blue
Thiazolyl Blue (MTT) is a cell-permeable and positively charged tetrazolium dye that is used to detect reductive metabolism in cells. Thiazolyl Blue is taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD (P) H-oxidoreductases. Thiazolyl Blue is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: MTT; Thiazolyl Blue Tetrazolium bromide; Methylthiazolyldiphenyl-tetrazolium bromide. CAS No. 298-93-1. Pack Sizes: 500 mg; 1 g. Product ID: HY-15924.
Thiazovivin
Thiazovivin is a potent ROCK inhibitor, which can protect human embryonic stem cells. Thiazovivin improves the efficiency of iPSC generation. Uses: Scientific research. Group: Signaling pathways. CAS No. 1226056-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13257.
Thidiazuron
Thidiazuron is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 51707-55-2. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-B0872.
Thiethylperazine
Thiethylperazine, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine is also a selective ABCC1 activator that reduces amyloid-β (Aβ) load in mice. Thiethylperazine has anti-emetic, antipsychotic and antimicrobial effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1420-55-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1794.
Thifensulfuron-methyl
Thifensulfuron-methyl is a sulfonylurea herbicide and mainly used for control of broadleaved weeds in wheat, corn, and soybean fields [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79277-27-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-W020020.
Thifluzamide
Thifluzamide, a broad-spectrum succinate dehydrogenase inhibitor (SDHI) fungicide, has been widely used in the controlling of a variety of fungal diseases in rice fields [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130000-40-7. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B2004.
Thioacetamide
Thioacetamide (TAA) is an indirect hepatotoxin and causes parenchymal cell necrosis. Thioacetamide requires metabolic activation by microsomal CYP2E1 to thioacetamide-S-oxide initially and then to thioacetamide-S-dioxide, which is a highly reactive metabolite, and its reactive metabolites covalently bind to proteins and lipids thereby causing oxidative stress and centrilobular necrosis. Thioacetamide can induce chronic liver fibrosis, encephalopathy and other events model [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Acetothioamide; TAA; Thiacetamide. CAS No. 62-55-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-Y0698.
Thiobencarb
Thiobencarb is an herbicide, can reduce growth, photosynthetic activity, and amount of rieske iron-sulfur protein in the diatom Thalassiosira pseudonana [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 28249-77-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-129792.
Thiocolchicine
Thiocolchicine, a derivative modified in the C Ring of Colchicine (HY-16569) with enhanced biological properties. Thiocolchicine is a potent inhibitor of tubulin polymerization ( IC 50 =2.5 μM) and competitively binds to tubulin with a K i of 0.7 μM. Thiocolchicine induces cell apoptosis [1] [2]. Thiocolchicine can be used as an ADC cytotoxin in ADC technology. Uses: Scientific research. Group: Signaling pathways. CAS No. 2730-71-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116852.
Thiocolchicoside
Thiocolchicoside is a competitive γ-aminobutyric acid type A (GAB A A) receptor antagonist and glycine receptor agonist in the central nervous system. Thiocolchicoside is a semisynthetic sulfur derivative of colchicoside. Thiocolchicoside is a muscle relaxant and has anti-inflammatory, and analgesic properties [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 602-41-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-N0301.
Thiodigalactoside
Thiodigalactoside (TDG) is an orally active and potent galectin (GAL) inhibitor with Kd values of 24 ?M, 49 ?M for GAL1 and GAL3, respectively[1]. Thiodigalactoside, a non-metabolizable disaccharide, has anti-inflammatory and anti-cancer activity. Thiodigalactoside dramatically reduces body weight gain in diet-induced obese rats[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TDG. CAS No. 51555-87-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg. Product ID: HY-130208.
Thioflavine S
Thioflavine S is a fluorescent histochemical marker of dense core senile plaques. Thioflavine S can be used for Alzheimer's research[1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Thioflavin S; Direct Yellow 7. CAS No. 1326-12-1. Pack Sizes: 100 mg. Product ID: HY-D0972.
Thioflavin T
Thioflavin T is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Basic Yellow 1. CAS No. 2390-54-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-D0218.
Thioglucosidase
Thioglucosidase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 9025-38-1. Pack Sizes: 25 U; 100 U. Product ID: HY-P2872.
Thioglycolate sodium
Sodium Thioglycolate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 367-51-1. Pack Sizes: 25 g. Product ID: HY-W115724.
Thiolactomycin
Thiolactomycin is an antibiotic. Thiolactomycin is active against Gram-negative anaerobes. Thiolactomycin also inhibits malaria and trypanosomes. Thiolactomycin is a FabB inhibitor. Thiolactomycin inhibits the synthesis of fatty acids and mycolic acids [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82079-32-1. Pack Sizes: 1 mg. Product ID: HY-122394.
Thiolutin
Thiolutin (Acetopyrrothin) is a disulfide-containing antibiotic and anti-angiogenic compound produced by Streptomyces. Thiolutin inhibits the JAMM metalloproteases Csn5, Associated-molecule-with-the-SH3-Domain-of-STAM (AMSH) and Brcc36 [1]. Thiolutin is a potent and selective inhibitor of endothelial cell adhesion accompanied by rapid induction of Heat-shock protein beta-1 (Hsp27) phosphorylation [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Acetopyrrothin. CAS No. 87-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N6712.
Thiomorpholine
Thiomorpholine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 123-90-0. Pack Sizes: 25 g. Product ID: HY-W007359.
Thiomyristoyl
Thiomyristoyl is a potent and specific SIRT2 inhibitor with an IC50 of 28 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1429749-41-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101278.
Thionicotinamide adenine dinucleotide
Thionicotinamide adenine dinucleotide (Thio-NAD) is a dinucleotide substrate [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Thio-NAD. CAS No. 4090-29-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-131924.
Thionin acetate
Thionin acetate (Thionine acetate) is a metachromic cationic histology dye used in biological staining widely. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Thionine acetate. CAS No. 78338-22-4. Pack Sizes: 500 mg; 1 g. Product ID: HY-D0955.
Thioperamide
Thioperamide (MR-12842) is a potent, orally available, brain penetrant and selective H3 receptor antagonist with a K i of 4.3 nM for inhibition of [ 3 H]histamine release. Thioperamide inhibits [ 3 H]histamine synthesis with a K i of 31 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MR-12842. CAS No. 106243-16-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-12206.
Thioperamide maleate
Thioperamide maleate (MR-12842 maleate) is a potent, orally available, brain penetrant and selective H3 receptor antagonist with a K i of 4.3 nM for inhibition of [ 3 H]histamine release. Thioperamide maleate inhibits [ 3 H]histamine synthesis with a K i of 31 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MR-12842 maleate. CAS No. 148440-81-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-12206A.
Thiophanate-Methyl
Thiophanate-Methyl is a systematic fungicide [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 23564-05-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0842.
Thiophene-3-carboxylic acid
Thiophene-3-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 88-13-1. Pack Sizes: 25 g. Product ID: HY-W004615.
Thioproperazine
Thioproperazine (RP 7843) is an orally active antipsychotic agent with calming, antiemetic activity. Thioproperazine is effective in promoting the release of dopamine in rat striatum. Thioproperazine can be used in studies of schizophrenia and bipolar disorder [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP 7843; SKF 5883; Thioperazine. CAS No. 316-81-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-A0151.
Thioredoxin reductase
Thioredoxin reductase (TrxR) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TrxR. CAS No. 9074-14-0. Pack Sizes: 50 μg. Product ID: HY-P2759.