MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Thioridazine | Thioridazine, an antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways with anti-angiogenic effect. Thioridazine shows antiproliferative and apoptosis induction effects in various types of cancer cells, with specificity on targeting cancer stem cells (CSCs) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 50-52-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0965A. |  |
| Thioridazine hydrochloride | Thioridazine hydrochloride, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine hydrochloride is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways with anti-angiogenic effect. Thioridazine hydrochloride shows antiproliferative and apoptosis induction effects in various types of cancer cells, with specificity on targeting cancer stem cells (CSCs) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130-61-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0965. | |
| Thiorphan | Thiorphan is a selective NEP (neprilysin) inhibitor with an IC 50 of 6.9 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 76721-89-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-W013375. | |
| Thiosemicarbazide | Thiosemicarbazide is a vitamin B6 antagonist with anti-acne activity. Thiosemicarbazide is also a well-known source in the synthesis of heterocycles, and its derivatives have potential anticancer activity. Thiosemicarbazide (TSC: HL1) reacts with metal salts, urea (U), to prepare Co(II) and Cu(I) metal complexes. Thiosemicarbazide is also used in the fields of media communications and optical storage, and in the spectrophotometric detection of metals [1] [2] [3] [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79-19-6. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-Y0032. | |
| Thiostrepton | Thiostrepton is a thiazole antibiotic which selectively inhibits FOXM1. FOXM1 binds to YAP/TEAD complex. YAP/TEAD/FOXM1 complex binding at regulatory regions of genes governing cell cycle may impact cell proliferation [1]. Uses: Scientific research. Group: Peptides. CAS No. 1393-48-2. Pack Sizes: 50 mg. Product ID: HY-B0990. | |
| Thio-TEPA | Thio-TEPA is a DNA alkylating agent, with antitumor activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 52-24-4. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-17574. | |
| THIP | THIP (Gaboxadol) is a selective extrasynaptic GABAA receptors ( eGABARs ) agonist (with blood-brain barrier permeability), shows an EC 50 value of 13 μM for δ-GABAAR. THIP induces strong tense GABAA -mediated currents in layer 2/3 neurons, but shows on effect on miniature IPSCs. THIP can be used in studies of sleep disorders [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Gaboxadol. CAS No. 64603-91-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10232. | |
| THIQ | THIQ is the first selective agonist of the melanocortin-4 receptor (MC4R) , with high affinity and potency for hMC4R ( IC 50 =1.2 nM, EC 50 =2.1 nM) and rMC4R ( IC 50 =0.6 nM, EC 50 =2.9 nM). THIQ maintains low potency at MC1R, MC3R and MC5R. THIQ plays a role in eliciting erectile activity in rodents. THIQ acts as a pharmacoperone of the MC4R rescuing the cell surface expression and signaling of some intracellularly retained MC4R mutants [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312637-48-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10624. | |
| Thiram-d12 | Thiram-d 12 is the deuterium labeled Thiram. Thiram, a fungicides, is widely used on seeds and as foliar agent on turf, vegetables and fruit.Thiram acts as a vulcanization accelerator in the rubber industry[1]. Thiram induces antioxidant defense and oxidative stress. Thiram can act as a prooxidant resulting in the formation of reactive oxygen species (ROS)[2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 69193-86-8. Pack Sizes: 1 mg. Product ID: HY-132426S. | |
| THK5351 | THK5351 can be radiolabeled and used as a radiotracer for in vivo imaging of tau pathology in the brain. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1707147-26-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101183. | |
| Thonzonium bromide | Thonzonium bromide is an antibacterial agent that is structurally similar to Farnesol (HY-Y0248A). Thonzonium bromide is also a monocationic surface-active agent, which inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo. Thonzonium bromide inhibits proton transport in a dose-dependent manner (EC 50 =69 μM) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 553-08-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1246. | |
| Thonzylamine | Thonzylamine is an orally active H 1 histamine receptor antagonist with good antihistaminic and antianaphylactic properties. Thonzylamine can be used for the research of hypersensitivity diseases, nasal congestion, allergic conjunctivitis and other allergic diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Neohetramine. CAS No. 91-85-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1317. | |
| THPN | THPN is a potent Nur77 agonist. THPN specifically binds the LBD of Nur77 (TR3) but not that of retinoic acid receptor α and PPARγ with a K d of 270 nM. THPN leads to Nur77 translocation to the mitochondria to induce autophagic cell death in melanoma [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 100079-26-3. Pack Sizes: 5 mg. Product ID: HY-113827. | |
| (Thr4,Gly7)-Oxytocin | (Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K+ channels. [1][2]. Uses: Scientific research. Group: Peptides. CAS No. 60786-59-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3467. | |
| THR-β agonist 1 | THR-β Agonist 1 is a potent and selective agonist of THR&beta. Thyroid hormone receptor mediates the physiological activity of thyroid hormones which plays a key role in normal growth and development of the body and in maintaining metabolic balance. THR-β Agonist 1 has the potential for the research of thyroid hormone receptor-related diseases (extracted from patent WO2021104288A1, compound 2) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2648403-17-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-142441. | |
| Thr-Leu | Thr-Leu is a dipeptide composed of threonine and leucine. Thr-Leu can be hydrolyzed in the peritoneal cavity to generate constituent amino acids, thereby increasing the osmotic pressure of the dialysate. Thr-Leu can be used for the kinetic study of amino acid-based peritoneal dialysis fluids [1]. Uses: Scientific research. Group: Peptides. CAS No. 50299-12-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W342021. | |
| Thrombin (MW 37kDa) | Thrombin (MW 37kDa) is a Na+-activated, allosteric serine protease that plays opposing functional roles in blood coagulation. Thrombin recognition sequence and can be used to digest GST-tagged proteins. Uses: Scientific research. Group: Signaling pathways. CAS No. 9002-4-4. Pack Sizes: 1000 U; 2000 U. Product ID: HY-114164. | |
| Thrombin, Pig blood | Thrombin, Pig blood is a key enzyme in the coagulation cascade, responsible for converting fibrinogen into fibrin. Thrombin, Pig blood activates platelet activation, endothelial cell function, and inflammatory responses by binding to PAR-1 and PAR-4 , which triggers G protein-coupled signaling pathways. Thrombin, Pig blood holds promise for research in coagulation and inflammation fields [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9002-4-4. Pack Sizes: 100 KU. Product ID: HY-114164C. | |
| Thromboxane B2 | Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation. Uses: Scientific research. Group: Signaling pathways. CAS No. 54397-85-2. Pack Sizes: 1 mg. Product ID: HY-113331. | |
| THX-B | THX-B is a potent and non-peptidic p75NTR (neurotrophin receptor p75) antagonist. THX-B can be used in the research of diabetic kidney disease, neurodegenerative and inflammatory disorders[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1372206-64-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137322. | |
| Thymalfasin | Thymalfasin is an immunomodulating agent able to enhance the Thl immune response. Uses: Scientific research. Group: Peptides. Alternative Names: Thymosin α1. CAS No. 62304-98-7. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P0091. | |
| Thymidine | Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: DThyd; NSC 21548. CAS No. 50-89-5. Pack Sizes: 500 mg; 1 g. Product ID: HY-N1150. | |
| Thymidine-5'-diphosphate-L-rhamnose disodium | Thymidine-5'-diphosphate-L-rhamnose disodium is the disodium form of Thymidine-5'-diphosphate-L-rhamnose (HY-N11102). Thymidine-5'-diphosphate-L-rhamnose disodium can be isolated from Occhromonas malhamensis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 214753-67-0. Pack Sizes: 1 mg. Product ID: HY-N11102A. | |
| Thymidine 5-diphosphate sodium | Thymidine 5-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5-thymidine monophosphate (dTMP), which requires ATP and Mg 2+. Thymidine 5-diphosphate sodium is further catalyzed by TMPK to thymidine 5-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5-diphosphate [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: dTDP sodium. CAS No. 108322-12-9. Pack Sizes: 5 mg. Product ID: HY-131576A. | |
| Thymidine-5'-monophosphate (disodium) salt | Thymidine-5'-monophosphate disodium salt is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 33430-62-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-128738. | |
| Thymidine 5-monophosphate p-nitrophenyl ester sodium | Thymidine 5-monophosphate p-nitrophenyl ester sodium (Compound 2a) is the derivative of thymidine 5'-phosphate (TMP). Thymidine 5-monophosphate p-nitrophenyl ester sodium penetrates mammalian cells, releases intracellular antimetabolite 5' nucleotides. Thymidine 5-monophosphate p-nitrophenyl ester sodium is potential as an antitumor prodrug [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 98179-10-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-137807. | |
| Thymine | Thymine, one of the four bases of DNA, is a substrate for rat liver dihydropyrimidine dehydrogenase ( DPD ), with a K m value of 2.2 μM, K i of 24 μM (using 5-FU as the DPD substrate), and a specific activity of 0.68 nmol/min/mg [1]. Uses: Scientific research. Group: Natural products. CAS No. 65-71-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W010450. | |
| Thymohydroquinone | Thymohydroquinone is a monoterpene molecule. Thymohydroquinone has antioxidant and anti-inflammatory properties. Thymohydroquinone can be used for pharmacokinetic studies and regulatory toxicity studies [1]. Uses: Scientific research. Group: Natural products. CAS No. 2217-60-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W196368. | |
| Thymol | Thymol is a TRPA1 agonist. Thymol induces cancer cell apoptosis. Thymol is the main monoterpene phenol occurring in essential oils isolated from plants belonging to the Lamiaceae family, and other plants such as those belonging to the Verbenaceae, Scrophulariaceae, Ranunculaceae and Apiaceae families. Thymol has antioxidant, anti-inflammatory, antibacterial and antifungal effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 89-83-8. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N6810. | |
| Thymol blue | Thymol Blue sodium is an acid-base indicator used to indicate changes in pH. Thymol Blue sodium fades from red to yellow at pH 1.2 to 2.8 and from yellow to blue at pH 8.0 to 9.6 [1]. Storage: protect from light. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Thymolsulphonephthalein. CAS No. 76-61-9. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-D0219. | |
| Thymol Blue sodium | Thymol Blue sodium is an acid-base indicator used to indicate changes in pH. Thymol Blue sodium fades from red to yellow at pH 1.2 to 2.8 and from yellow to blue at pH 8.0 to 9.6 [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 62625-21-2. Pack Sizes: 500 mg; 1 g. Product ID: HY-D0219A. | |
| Thymol iodide | Thymol iodide is a compound of Iodide and Thymol. Thymol iodide acts as a substitute for iodoform [1]. Thymol iodide is an iodine derivative of Thymol (a phenol derived from thyme oil), which is mostly used as mild antiseptic and fungicide [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 552-22-7. Pack Sizes: 500 mg; 1 g. Product ID: HY-B1796. | |
| Thymolphthalein | Thymolphthalein is an electrochemically active dye due to the presence of thymol fragments. Thymolphthalein is a Phthalein dye used as an acid-base indicator. It is colourless in acid pH and is blue in basic pH [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 125-20-2. Pack Sizes: 100 mg. Product ID: HY-D0265. | |
| Thymol (Standard) | Thymol (Standard) is the analytical standard of Thymol. This product is intended for research and analytical applications. Thymol is a TRPA1 agonist. Thymol induces cancer cell apoptosis. Thymol is the main monoterpene phenol occurring in essential oils isolated from plants belonging to the Lamiaceae family, and other plants such as those belonging to the Verbenaceae, Scrophulariaceae, Ranunculaceae and Apiaceae families. Thymol has antioxidant, anti-inflammatory, antibacterial and antifungal effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 89-83-8. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6810R. | |
| Thymopentin | Thymopentin is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs) [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 69558-55-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N7122. | |
| Thymopentin acetate | Thymopentin acetate is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin acetate is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin acetate enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs) [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 89318-88-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N7122A. | |
| Thymoquinone | Thymoquinone is an orally active natural product isolated from N. sativa Thymoquinone down-regulates the VEGFR2-PI3K-Akt pathway. Thymoquinone has antioxidant, anti-inflammatory, anticancer, antiviral, anticonvulsant, antifungal, antiviral, antiangiogenic activity and hepatoprotective effects. Thymoquinone can be used to study Alzheimer's disease, cancer, cardiovascular disease, infectious disease and inflammation [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 490-91-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-D0803. | |
| Thyroglobulin | Thyroglobulin is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Thyroglobulin from bovine. CAS No. 9010-34-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107903. | |
| Thyrotropin | Thyrotropin (TSH, Pretiron) is a thyroid-stimulating hormone produced by thyrotrope cells in the anterior pituitary gland. Thyrotropin regulates the endocrine function of the thyroid. Thyrotropin induces transcriptional regulation of TH-gatekeeper genes in tanycytes through the Tshr/Gαq/PKC pathway. Thyrotropin prevents Apoptosis. Thyrotropin has an association of low levels with increased bone remodeling, reduced bone mass and a high fracture risk in mice. Thyrotropin is promising for research of skeletal remodeling, hyperthyroidism [1] [2] [3] [4] [13]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSH; Pretiron. CAS No. 9002-71-5. Pack Sizes: 5 μg; 10 μg. Product ID: HY-107916. | |
| Thyrotropin-Releasing Hormone (TRH), Free Acid | Thyrotropin-Releasing Hormone (TRH), Free Acid (TRH-OH) is a physiological metabolite of Thyrotropin-Releasing Hormone. Uses: Scientific research. Group: Peptides. Alternative Names: TRH-OH. CAS No. 24769-58-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1529. | |
| Thyroxine sulfate | Thyroxine sulfate is a thyroid hormone metabolite. Uses: Scientific research. Group: Natural products. Alternative Names: T4 Sulfate. CAS No. 77074-49-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101406. | |
| THZ1 | THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM. THZ1 also inhibits the closely related kinases CDK12 and CDK13 and downregulates MYC expression[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1604810-83-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-80013. | |
| THZ1 Hydrochloride | THZ1 Hydrochloride is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM. THZ1 Hydrochloride also inhibits the closely related kinases CDK12 and CDK13 and downregulates MYC expression[1][2]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-80013A. | |
| THZ531 | THZ531 is a selective and covalent inhibitor of both CDK12 and CDK13 with IC50s of 158 nM and 69 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1702809-17-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103618. | |
| THZ-P1-2 | THZ-P1-2 is a first-in-class and selective PI5P4K inhibitor, with an IC50 of 190 nM for PI5P4K?. THZ-P1-2 covalently targets cysteines on a disordered loop in PI5P4K?/?/?. THZ-P1-2 causes autophagy disruption and upregulates TFEB signaling. THZ-P1-2 displays anticancer activity in leukemia cell lines[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2058075-45-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136351. | |
| TI17 | TI17 is an inhibitor of the thyroid hormone receptor-interacting protein Trip13 and has anticancer activity. TI17 effectively inhibits multiple myeloma (MM) cell proliferation and induces cell cycle arrest and apoptosis. Trip13 is an AAA-ATPase that mediates double-strand break (DSB) repair; TI17 inhibits Trip13 function and increases DNA damage [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1005178-02-8. Pack Sizes: 1 mg. Product ID: HY-Q04764. | |
| Tiafenacil | Tiafenacil is a new protoporphyrinogen IX oxidase ( PPO )-inhibiting herbicide, with IC 50 values of 22 to 28 nM for various plant species, including amaranth ( Amaranthus tuberculatus ), soybean ( Glycine max ), arabidopsis ( Arabidopsis thaliana ), and rapeseed ( Brassica napus ) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1220411-29-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137551. | |
| Tiagabine hydrochloride | Tiagabine hydrochloride is an anticonvulsant agent and a selective inhibitor of the GAT-1 GABA transporter with a Ki of ?0.1 μM. Tiagabine hydrochloride potently and selectively inhibits GABA reuptake with IC 50 s of 67, 446 and 182 nM for [3H] GABA uptake in synaptosomes, neurons and glia, respectively. Tiagabine hydrochloride has neuroprotective properties [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NO050328 hydrochloride; NO328 hydrochloride; TGB hydrochloride. CAS No. 145821-59-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0696A. | |
| Tiamulin | Tiamulin (Thiamutilin) is a diterpenic antibiotic that is widely used in pigs and poultry for the control of infectious diseases. Tiamulin is effectively used in the study of airsacculitis, which is primarily caused by Mycoplasma spp [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Thiamutilin. CAS No. 55297-95-5. Pack Sizes: 10 mM * 1 mL; 250 mg; 1 g. Product ID: HY-B2060. | |
| Tiamulin fumarate | Tiamulin (Thiamutilin) fumarate is a diterpenic antibiotic that is widely used in pigs and poultry for the control of infectious diseases. Tiamulin fumarate is effectively used in the study of airsacculitis, which is primarily caused by Mycoplasma spp [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Thiamutilin fumarate. CAS No. 55297-96-6. Pack Sizes: 10 mM * 1 mL; 250 mg; 1 g. Product ID: HY-B2060A. | |
| Tianagliflozin | Tianagliflozin is a sodium/glucose cotransporter 2 ( SGLT-2 ) inhibitor with potential for investigation in type 2 diabetes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1461750-27-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116223. | |
| Tianeptine | Tianeptine is a selective facilitator of 5-HT uptake. Tianeptine has no affinity for a wide range of receptors, including 5-HT and dopamine (IC 50 >10 μM) and has no effect on noradrenalin or dopamine uptake. Tianeptine has antidepressant, anxiolytic, analgesic and neuroprotective activities [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 72797-41-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-90003. | |
| Tianeptine sodium salt | Tianeptine sodium salt is a selective facilitator of 5-HT uptake. Tianeptine sodium salt suppresses MMP-9 via suppression of the PI3K/Akt -mediated NF-κB pathway. Tianeptine sodium salt has no affinity for a wide range of receptors, including 5-HT and dopamine (IC 50 >10 μM) and has no effect on noradrenalin or dopamine uptake. Tianeptine sodium salt has antidepressant, anxiolytic, analgesic and neuroprotective activities [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 30123-17-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-90003A. | |
| Tiapride hydrochloride | Tiapride hydrochloride is a selective and orally active D 2 and D 3 dopamine receptors antagonist with IC 50 values of 110-320 nM and 180 nM, respectively. Tiapride hydrochloride shows anti-dyskinetic activity and anxiolytic activity. Tiapride hydrochloride is a neuroleptic agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 51012-33-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1196. | |
| Tiaprofenic acid | Tiaprofenic acid is an orally active nonsteroidal anti-inflammatory agent (NSAID) with anti-inflammatory and analgesic potency. Tiaprofenic acid inhibits prostaglandin synthesis by suppressing cyclo-oxygenase (COX). Tiaprofenic acid can be used in the treatment of rheumatic diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 33005-95-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-106579. | |
| Tiaramide hydrochloride | Tiaramide (RHC 2592-A) hydrochloride is an analgesic agent with antiallergic activity, and is also a non-steroidal, anti-inflammatory compound. Tiaramide hydrochloride inhibits histamine release [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RHC 2592-A. CAS No. 35941-71-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-13405. | |
| Tiazofurin | Tiazofurin (NSC 286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase (IMPDH) [1]. Tiazofurin also has anti- orthopoxvirus and anti-variola activities [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 286193; Riboxamide. CAS No. 60084-10-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114570. | |
| TIBI | TIBI is a potent and ATP-competitive inhibitor of Rio1 ( IC 50 : 0.09 μM, K i : 0.05 μM). TIBI enhances the thermostability of the enzyme Rio1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1196457-06-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116559. | |
| Tibolone | Tibolone is a broad spectrum gonadal steroid agonist with progestagenic, androgenic, and estrogenic activities. Tibolone can be used for postmenopausal osteoporosis research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5630-53-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-123047. | |
| Ticagrelor | Ticagrelor (AZD6140) is a reversible oral P2Y12 receptor antagonist for the treatment of platelet aggregation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD6140; AR-C 126532XX. CAS No. 274693-27-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-10064. | |
| Ticagrelor EP Impurity E hydrochloride | Ticagrelor EP Impurity E hydrochloride is a conformationally restricted phenethylamine. Uses: Scientific research. Group: Signaling pathways. CAS No. 1402222-66-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-I0180A. | |
| Ticarcillin sodium | Ticarcillin sodium is an injectable antibiotic for the treatment of Gram-negative bacteria, particularly Pseudomonas aeruginosa. It is also one of the few antibiotics capable of treating Stenotrophomonas maltophilia infections [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 29457-07-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100577. | |
| Ticlopidine | Ticlopidine (PCR 5332), an antithrombotic proagent, acts as an allosteric, noncompetitive inhibitor of CD39 with the IC50 of 81.7 μM. Ticlopidine blocks several NTPDase isoenzymes with IC50s of 170 μM and 149 μM for NTPDase2 and NTPDase3, respectively. Ticlopidine is an inhibitor of CYP2C19 human liver cytochrome. Ticlopidine inhibits CYP2C9 and CYP3A4 with IC50s of 26.0 and 32.3 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PCR 5332. CAS No. 55142-85-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100386. | |
| Ticlopidine hydrochloride | Ticlopidine hydrochloride is an adenosine diphosphate (ADP) receptor inhibitor against platelet aggregation with IC50 of ~2 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 53885-35-1. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B0153A. | |
| Tideglusib | Tideglusib (NP031112) is an irreversible GSK-3 inhibitor with IC50s of 5 nM and 60 nM for GSK-3?WT (1 h preincubation) and GSK-3?C199A (1 h preincubation), respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NP031112. CAS No. 865854-05-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14872. | |
| Tidiacic | Tidiacic is a hepatoprotective agent that acts as an antioxidant and a sulfur donor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 30097-06-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W024241. | |
| Tie2 kinase inhibitor 1 | Tie2 kinase inhibitor 1 (compound 5) is a potent, selective Tie2 kinase inhibitor with an IC50 of 250 nM[1]. Tie2 kinase inhibitor 1 has anti-cancer activity[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 948557-43-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100556. | |
| Tie2 kinase inhibitor 2 | Tie2 kinase inhibitor 2 (compound 7) is a selective Tie2 kinase inhibitor with an IC50 value of 1 ?M. Tie2 kinase inhibitor 2 inhibits endothelial cell tube formation, and can be used for Tie2-mediated angiogenic disorders research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1020412-97-8. Pack Sizes: 1 mg. Product ID: HY-113571. | |
| Tienilic acid | Tienilic acid (Ticrynafen; ANP 3624) acts as a diuretic hypotensive agent. However, Tienilic acid induces hepatotoxicity. Tienilic acid is converted into electrophilic metabolites by cytochrome P450 (CYP) in vitro [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ticrynafen; ANP 3624. CAS No. 40180-04-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-21065. | |
| Tifcemalimab | Tifcemalimab (JS004) is a humanized anti- BTLA (B and T lymphocyte attenuation factor) monoclonal antibody. Tifcemalimab blocks the interaction of HVEM-BTLA by binding to BTLA, and thus blocks the inhibitory signaling pathway mediated by BTLA. Tifcemalimab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: JS004. CAS No. 2236068-83-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99961. | |
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