MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| 9-Fluorenylmethanol | 9-Fluorenylmethanol is an N-protecting reagent that can be used in peptide synthesis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24324-17-2. Pack Sizes: 10 g. Product ID: HY-W009876. |  |
| 9-Fluorenylmethyl carbamate | 9-Fluorenylmethyl carbamate (Fmoc-NH2) is an amide compound with an Fmoc protecting group, which can be used as a photobase initiator to prepare organosilane-based proton exchange membranes [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Fmoc-NH2. CAS No. 84418-43-9. Pack Sizes: 5 g; 10 g; 25 g. Product ID: HY-W015987. | |
| 9-Fluorenylmethyl carbazate | 9-Fluorenylmethyl carbazate is used as a fluorophore reagent for a fluorimetric detection of glycans [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 35661-51-9. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-W017873. | |
| 9H-Carbazol-4-ol | 9H-Carbazol-4-ol (4-Hydroxycarbazole) can be used as an aromatic heterocyclic compound with widespread applications in organic synthesis, as well as certain biochemical and physiological effects. 9H-Carbazol-4-ol is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 4-Hydroxycarbazole. CAS No. 52602-39-8. Pack Sizes: 5 g; 25 g. Product ID: HY-W016331. | |
| 9-ING-41 | 9-ING-41 (Elraglusib) is a maleimide-based ATP-competitive and selective glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC 50 of 0.71 μM. 9-ING-41 significantly leads to cell cycle arrest, autophagy and apoptosis in cancer cells. 9-ING-41 has anticancer activity and has the potential for enhancing the antitumor effects of chemotherapeutic agents [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Elraglusib. CAS No. 1034895-42-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113914. | |
| 9'''-Methyl salvianolate B | 9'''-Methyl salvianolate B is a methanolic extract of Cynoglossum columnae Ten. plants [1]. Uses: Scientific research. Group: Natural products. CAS No. 1167424-32-9. Pack Sizes: 25 mg; 1 mg; 5 mg; 10 mg. Product ID: HY-N5041. | |
| 9-OAHSA | 9-OAHSA is a fatty acid ester of hydroxy fatty acids (FAHFAs). 9-OAHSA shows anti-inflammatory effects via inhibiting cytokine production and reduces IL-1β and IL-6 expression. 9-OAHSA is also a protective molecule to prevent colon carcinoma cells from apoptotic cell death [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 154086-90-5. Pack Sizes: 1 mg (17.70 mM * 100 μL in Methyl acetate). Product ID: HY-131934. | |
| 9-Octadecynoic acid | 9-Octadecynoic acid is a DNA binding agent with a dissociation constant of 1.8 mM. 9-Octadecynoic acid is also an agonist for peroxisome proliferator-activated receptor γ ( PPARγ ) [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 506-24-1. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W341997. | |
| 9-Oxooctadecanoic acid | 9-Oxooctadecanoic acid (9-Oxostearic acid; 9-Ketostearic acid) is an ester product. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9-Oxostearic acid; 9-Ketostearic acid. CAS No. 4114-74-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W670044. | |
| 9-PAHSA | 9-PAHSA is an orally available anti-inflammatory lipid that lowers blood sugar and reduces inflammation. 9-PAHSA also improved carotid vascular calcification and attenuates cardiac hypertrophy and dysfunction in db/db mice. 9-PAHSA increases the viability of steatosis primary mouse hepatocytes (PMH). 9-PAHSA can be used in research on diabetes, inflammation, and cardiovascular disease [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1481636-31-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120657. | |
| 9-Phenanthrol | 9-Phenanthrol (9-Hydroxyphenanthrene) is a selective TRPM4 inhibitor with an IC 50 of 17 μM. 9-Phenanthrol has no inhibitory activity on TRPM5, TRPC6, and CFTR. 9-Phenanthrol can be used for the research of ischemia-reperfusion injury [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9-Hydroxyphenanthrene; NSC 50554. CAS No. 484-17-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg. Product ID: HY-108457. | |
| 9S-HODE | 9S-HODE (Alpha-dimorphecolic acid) is an octadecadienoic acid and the main active derivative of linoleic acid, which can reduce the viability of HL-60 cells and induce apoptosis. 9S-HODE is rich in lipid peroxidation (LPO) products and is almost an ideal marker for LPO [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Alpha-dimorphecolic acid. CAS No. 73543-67-6. Pack Sizes: 100 μg (5.31 mM * 63.5 μL in Ethanol). Product ID: HY-113455. | |
| 9S-HODE-d4 | 9S-HODE-d 4 (Alpha-dimorphecolic acid-d 4 ) is the deuterium labeled 9S-HODE (HY-113455) [1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Alpha-dimorphecolic acid-d4. CAS No. 890955-25-6. Pack Sizes: 25 μg (332.81 μM * 250 μL in Ethanol). Product ID: HY-113455S. | |
| 9(S)-HpODE | 9(S)-HpODE is produced by the action of arachidonate 5-LO on linoleic acid. It can be further metabolized by potato hydroperoxide dehydratase to colneleic acid. Uses: Scientific research. Group: Natural products. Alternative Names: 9-D-Hydroperoxylinoleic acid. CAS No. 29774-12-7. Pack Sizes: 50 μg (1.60 mM * 100 μL in Ethanol). Product ID: HY-118149. | |
| 9(Z),11(E)-Conjugated linoleic acid methyl ester | 9(Z),11(E)-Conjugated linoleic acid methyl ester (9Z,11E-CLA; Methyl 9(Z),11(E)-octadecadienoate; (9Z,11E)-SFE 19:2) is an isomer of Linoleic acid (HY-N0729). Conjugated linoleic acid is a bioactive fatty acid, which can improve body composition, enhance immune system function, exhibits anti-cancer and antiatherosclerosis effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9Z,11E-CLA; Methyl 9(Z),11(E)-octadecadienoate; (9Z,11E)-SFE 19:2. CAS No. 13058-52-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-124370. | |
| A1899 | A1899 is a potent and highly selective blocker of the K 2P channel TASK-1. A1899 has IC 50 values of 35.1 nM and 7 nM for TASK-1 channels expressed in oocytes and CHO cells, respectively. A1899 is also an I Kur blocker that can be used for the research of cardiovascular diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S20951. CAS No. 498577-46-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103067. | |
| A2764 dihydrochloride | A2764 dihydrochloride is a highly selective inhibitor of TRESK (TWIK-related spinal cord K + channel, K2P18.1), which has moderate inhibitory effects on TREK-1 and TALK-1. A2764 dihydrochloride is more sensitive to the activated mTRESK channels ( IC 50 =6.8 μM) than the basal current. A2764 dihydrochloride can lead to cell depolarization and increased excitability in native cells, it has the potential for probing the role of TRESK channel in migraine and nociception [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 861038-72-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-135809. | |
| A-286982 | A-286982 is a potent and allosteric LFA-1/ICAM-1 interaction inhibitor with IC 50 s of 44 nM and 35 nM in an LFA-1/ICAM-1 binding and LFA-1-mediated cellular adhesion assay, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 280749-17-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107587. | |
| A2A receptor antagonist 1 | A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A 2A receptor and A 1 receptor with K i values of 4 and 264 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPI-444 analog. CAS No. 443103-97-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102024. | |
| A3334 | A3051 is a potent and orally active inhibtor of CXXC5-DVL extracted from patent WO2020079569, has an IC 50 of 63.06 nM. A3334 can be used for the research of high fat diet (HFD)-induced and methionine-choline deficient diet (MCD)-induced phenotypes such as obesity, diabetes, and NASH [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 854171-31-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-131448. | |
| A-350619 hydrochloride | A-350619 hydrochloride is a soluble guanylate cyclase ( sGC ) activator. A-350619 hydrochloride can be used in the study of erectile dysfunction [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1217201-17-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107548. | |
| A-3 hydrochloride | A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA ( K i =4.3 μM), casein kinase II ( K i =5.1 μM) and myosin light chain kinase (MLCK) ( K i =7.4 μM). A-3 hydrochloride also inhibits PKC and casein kinase I with K i values of 47 μM and 80 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 78957-85-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-125957. | |
| A 410099.1 | A 410099.1 is a BIRC inhibitor, with EC 50 values for BIRC2 , BIRC3 , BIRC4 , BIRC7 , and BIRC8 are 4.6, 9.2, 15.6, 19.9, and 93.9 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 762274-58-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-50685. | |
| A 438079 | A 438079 is a potent, and selective P2X 7 receptor antagonist with pIC 50 of 6.9. Uses: Scientific research. Group: Signaling pathways. CAS No. 899507-36-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15488. | |
| A 438079 hydrochloride | A 438079 (hydrochloride) is a potent, and selective P2X 7 receptor antagonist with pIC 50 of 6.9. Uses: Scientific research. Group: Signaling pathways. CAS No. 899431-18-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15488A. | |
| A-582941 dihydrochloride | A-582941 dihydrochloride is a potent, selective and brain-penetrant partial agonist of α7 nAChR , with K i s of 10.8 and 16.7 nM in rat brain membranes and human frontal cortex, respectively. A-582941 dihydrochloride also binds to human 5-HT 3 receptor with a K i of 150 nM. A-582941 has the potential for cognitive deficits associated with various neurodegenerative and psychiatric disorders research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 848591-90-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-59201A. | |
| A-61603 | A-61603 is a selective α 1A -adrenergic receptor agonist [1]. A-61603 increases the frequency of spontaneous Ca 2+ transients in rat ventricular myocytes in vitro [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 107756-30-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101366. | |
| A-65186 | A-65186 is a CCK-A receptor antagonist with the activity of inhibiting CCK8-induced amylase secretion. A-65186 has high binding affinity for pancreatic CCK-A receptors, is more than 500 times more selective for CCK-A receptors than for CCK-B receptors, and can inhibit CCK8-induced amylase secretion. Uses: Scientific research. Group: Signaling pathways. CAS No. 119295-94-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-118194. | |
| A66 | A66 is a highly specific and selective p110α inhibitor with an IC 50 of 32 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1166227-08-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13261. | |
| A68930 hydrochloride | A68930 hydrochloride, as a dopamine D1 receptor agonist, can be used for the research of bronchiectasis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130465-39-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-103431. | |
| A-77636 hydrochloride | A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist ( pK i =7.40; K i =39.8 nM) with antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 145307-34-2. Pack Sizes: 5 mg. Product ID: HY-103416. | |
| A-784168 | A-784168 is a potent and orally active inhibitor of vanilloid receptor type 1 ( TRPV1 ). Vanilloid receptor type 1 (TRPV1) is a ligand-gated nonselective cation channel that is considered to be an important integrator of various pain stimuli such as endogenous lipids, capsaicin, heat, and low pH. A-784168 has good CNS penetration [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 824982-41-4. Pack Sizes: 5 mg. Product ID: HY-108460. | |
| A-7 hydrochloride | A-7 hydrochloride (Ophobolin A) is a calmodulin antagonist and can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ophobolin A. CAS No. 79127-24-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100914. | |
| A 83-01 | A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase , type I nodal receptor ALK4 and type I nodal receptor ALK7 , with IC 50 s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5 , ALK4 and ALK7 , respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 909910-43-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10432. | |
| A 83-01 sodium | A 83-01 sodium is a potent inhibitor of TGF-β type I receptor ALK5 kinase , ALK4 and ALK7 , with IC 50 s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5 , ALK4 and ALK7 , respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2828431-89-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10432A. | |
| A 85380 hydrochloride | A 85380 hydrochloride is a novel, high affinity neuronal nicotinic acetylcholine receptor ( nAChR ) agonist. A 85380 hydrochloride exhibits selectivity for the α4β2 nAChR subtypes. A 85380 hydrochloride has a broad-spectrum analgesic profile [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 174740-86-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-110131. | |
| A-966492 | A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with K i of 1 nM and 1.5 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 934162-61-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-10614. | |
| A-967079 | A-967079 is a selective TRPA1 receptor antagonist with IC 50 s of 67 nM and 289 nM at human and rat TRPA1 receptors, respectively, and has good penetration into the CNS. Uses: Scientific research. Group: Signaling pathways. CAS No. 1170613-55-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108463. | |
| A-971432 | A-971432 is a potent, selective and orally active sphingosine-1-phosphate (S1P) receptor 5 agonist with IC 50 s of.362, >10, 0.006 μM for S1P1, S1P3, S1P5 respectively. A-971432 protects blood - brain barrier (BBB) homeostasis. A-971432 reverses age-related cognitive decline. A-971432 has the potential for the research of alzheimers disease or multiple sclerosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1240308-45-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-110291. | |
| AA147 | AA147 is a endoplasmic reticulum (ER) proteostasis regulator. AA147 promotes protection against oxidative damage in neuronal cells and prevents endothelial barrier dysfunction by activating ATF6 arm (selectively) of the unfolded protein response (UPR) and the NRF2 oxidative stress response. AA147 can rebalances XBP1s expression in vivo, and also induces survival motor neuron (SMN) expression and spinal motorneuron (MN) protection [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 393121-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124293. | |
| AA74-1 | AA74-1 is a potent and selective inhibitor of APEH. AA74-1 significantly increases T cells proliferation by blocking the APEH activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1361532-00-4. Pack Sizes: 1 mg. Product ID: HY-134932. | |
| AACA | AACA is an inhibitor for sclerostin , that binds sclerostin on loop3 region with K d of 15.4 nM. AACA exhibits anti-osteoporosis activity through Wnt signaling pathway [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2515609-54-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163513. | |
| AACOCF3 | AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeant trifluoromethyl ketone analog of arachidonic acid. AACOCF3 is a potent and selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). AACOCF3 blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets. AACOCF3 has the potential for the research of cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Arachidonyl trifluoromethyl ketone. CAS No. 149301-79-1. Pack Sizes: 5 mg (28.05 mM * 500 μL in Ethanol); 10 mg (28.05 mM * 1 mL in Ethanol). Product ID: HY-108611. | |
| AAMU | AAMU (5-Acetylamino-6-amino-3-methyluracil) is the main metabolite of caffeine in the human body [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-Acetylamino-6-amino-3-methyluracil. CAS No. 19893-78-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-113118. | |
| AAPH | AAPH (2,2'-Azodiisobutyramidine dihydrochloride) has an effect of radical generation. AAPH induces oxidative stress and erythrocyte hemolysis [1]. AAPH decomposes at 37°C to generate an alkyl radical, is used as an initiator. In the presence of oxygen, these alkyl radicals will be converted to peroxyl radicals that can cause lipid peroxidation and loss of erythrocyte membrane integrity, which could ultimately lead to hemolysis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,2'-Azodiisobutyramidine dihydrochloride. CAS No. 2997-92-4. Pack Sizes: 1 g; 5 g. Product ID: HY-Y0525. | |
| AAZ-A 154 | AAZ-A 154 is a selective, competitive and non-hallucinogenic 5-HT2AR antagonist. AAZ-A 154 can promote neuronal growth and produce long-lasting beneficial behavioral effects in rodents [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2481740-94-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153015. | |
| AB21 hydrochloride | AB21 hydrochloride is a potent and selective S1R antagonist with K i s of 13, 102 nM for S1R and S2R. AB21 hydrochloride has the effect of reducing mechanical hypersensitivity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3026677-24-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149854B. | |
| AB-423 | AB-423 is an inhibitor of HBV capsid assembly, and potent inhibits HBV replication with EC 50 /EC 90 of 0.08-0.27 μM/0.33-1.32 μM in cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-DVR-23. CAS No. 1572510-80-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112142. | |
| AB-836 | AB-836 is an orally active HBV capsid inhibitor. AB-836 inhibits viral replication by interacting with HBV core protein [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2445597-31-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148348. | |
| Abacavir | Abacavir is an orally active and competitive nucleoside reverse transcriptase inhibitor. Abacavir can inhibits the replication of HIV. Abacavir shows anticancer activity in prostate cancer cell lines. Abacavir can trespass the blood-brain-barrier and suppresses telomerase activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 136470-78-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-17423. | |
| Abacavir sulfate | Abacavir sulfate (Abacavir Hemisulfate) is a competitive, orally active nucleoside reverse transcriptase inhibitor. Abacavir sulfate can inhibits the replication of HIV. Abacavir sulfate shows anticancer activity in prostate cancer cell lines. Abacavir sulfate can trespass the blood-brain-barrier and suppresses telomerase activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abacavir Hemisulfate; ABC sulfate. CAS No. 188062-50-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17423A. | |
| Abaecin | Abaecin is an antibacterial response peptide. Abaecin shows specific activity against an Apidaecin-resistant Xanthomonas strain [1]. Uses: Scientific research. Group: Peptides. CAS No. 123997-18-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5714. | |
| Abafungin | Abafungin, a antifungal agent, inhibitis the transmethylation at the C-24 position of the sterol side chain, catalyzed by the enzyme sterol-C-24-methyltransferase. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-W-6341. CAS No. 129639-79-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-119847. | |
| Abagovomab | Abagovomab (Anti-Human CA-125 Recombinant Antibody) is a murine monoclonal anti-idiotypic antibody, against the tumor-associated antigen, CA-125. Abagovomab is generated by a mouse hybridoma, can imitate the human TAA, CA-125. Abagovomab can elicit humoral and cellular immune responses against ovarian cancer (oc) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human CA-125 Recombinant Antibody. CAS No. 792921-10-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99276. | |
| Abaloparatide | Abaloparatide (BA 058) is a parathyroid hormone receptor 1 (PTHR1) analog. Abaloparatide also is a selective PTHR1 activator. Abaloparatide enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide enhances bone formation and cortical structure in mice. Abaloparatide has the potential for the research of osteoporosis [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: BA 058; BIM 44058. CAS No. 247062-33-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108742. | |
| Abametapir | Abametapir is a metalloproteinase (MMP) inhibitor which is able to target metalloproteinases critical to egg hatching and louse development. Abametapir can inhibit hatching of both head and body louse [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1762-34-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-W004546. | |
| Abarelix | Abarelix (R3827; PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer treatment. Uses: Scientific research. Group: Peptides. Alternative Names: R3827; PPI 149. CAS No. 183552-38-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13534. | |
| Abarelix Acetate | Abarelix Acetate (PPI 149 Acetate; R 3827 Acetate) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer research [1]. Uses: Scientific research. Group: Peptides. Alternative Names: PPI 149 Acetate; R 3827 Acetate. CAS No. 547741-72-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13534A. | |
| Abatacept | Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains) [1]. Abatacept is a selective T-cell co-stimulation modulator and a protein agent for the autoimmune diseases [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CTLA4lg; BMS-188667. CAS No. 332348-12-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108829. | |
| Abatacept (powder) | Abatacept (CTLA4lg; BMS-188667) powder is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). Abatacept powder is a selective T-cell co-stimulation modulator and a protein agent for the autoimmune diseases [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CTLA4lg (powder); BMS-188667 (powder). CAS No. 332348-12-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108829A. | |
| ABBV-CLS-7262 | ABBV-CLS-7262 is modulates the integrated stress response (ISR) for inhibition of ISR-related diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fosigotifator THAM sodium. CAS No. 2945073-88-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-153399A. | |
| Abciximab | Abciximab (C7E3), a chimeric mouse/human monoclonal antibody fragment, is a glycoprotein (GP) IIb/IIIa inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: C7E3. CAS No. 143653-53-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9934. | |
| Abelacimab | Abelacimab (MAA868) is a fully human IgG1 monoclonal antibody that binds with high affinity to the catalytic structural domain of FXI and locks it in the zymogen conformation, thereby preventing its activation by FXIIa or thrombin. Abelacimab can be used in thromboembolic disease studies [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MAA868. CAS No. 2098724-83-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99415. | |
| Abemaciclib | Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC 50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY2835219. CAS No. 1231929-97-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-16297A. | |
| Abemaciclib metabolite M18 hydrochloride | Abemaciclib metabolite M18 (LSN3106729) hydrochloride, the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LSN3106729 hydrochloride. CAS No. 2704316-82-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126534A. | |
| Abemaciclib methanesulfonate | Abemaciclib methanesulfonate (LY2835219 methanesulfonate) is a selective CDK4/6 inhibitor with IC 50 s of 2 nM and 10 nM for CDK4 and CDK6, respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY2835219 methanesulfonate. CAS No. 1231930-82-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16297. | |
| Aβ42-IN-2 | Aβ42-IN-2 (compound example 36) is a γ-secretase modulator. Aβ42-IN-2 has an IC 50 of 6.5 nM for Αβ 42. Aβ42-IN-2 can be used for the research of Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1914989-80-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136866. | |
| Abexinostat | Abexinostat (CRA 024781) is a novel pan- HDAC inhibitor mostly targeting HDAC1 with K i of 7 nM. Abexinostat also inhibits metallo-β-lactamase domain-containing protein?2 ( MBLAC2 ) hydrolase activity with an EC 50 below 10 nM [1] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CRA 024781; PCI-24781. CAS No. 783355-60-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10990. | |
| ABH hydrochloride | ABH (hydrochloride) is an orally active arginase inhibitor ( K i = 8.5 nM). ABH hydrochloride promotes NO production and reduces the expression of inflammatory response-related molecules ( ICAM-1 , VCAM-1 , MCP-1 ). ABH hydrochloride improves erectile function, reduces lung damage, promotes wound healing, reduces arterial blood pressure, and improves vascular fibrosis [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Signaling pathways. CAS No. 194656-75-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-112868B. | |
| Abietic acid | Abietic acid, an orally active diterpene isolated from Colophony, displays significant anti-proliferative, anti-inflammatory, anti-obesity effect, bacteriostatic, cell cycle arresting and pro-apoptotic activities. Abietic acid inhibits lipoxygenase activity for allergy. Abietic acid enhances cell migration and tube formation in HUVECs. Abietic acid induces significant angiogenic potential, which is associated with upregulation of extracellular signal-regulated kinase (ERK) and p38 expression. Abietic acid attenuates sepsis-induced lung injury by inhibiting nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway to inhibit M1 macrophage polarization. Abietic acid exhibits a positive effect against liver injury by attenuating inflammation and ferroptosis. Abietic acid shows accelerated wound closure in a mouse model of cutaneous wounds. Abietic acid significantly reduces the proliferation and growth of NSCLC cells by IKKβ inhibition.Additionally, Abietic acid ameliorates psoriasis-like inflammation and modulates gut microbiota in mice. Abietic acid is promising for research in non-small-cell lung cancer (NSCLC), liver injury-related deseases and psoriasis [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. CAS No. 514-10-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N6871. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.