MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| A-1331852 | A-1331852 is an orally available BCL-XL selective inhibitor with a Ki of less than 10 pM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1430844-80-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19741. |  |
| A1874 | A1874 is a nutlin-based (MDM2 ligand) and BRD4-degrading PROTAC with a DC50 of 32 nM (induce BRD4 degradation in cells). Effective in inhibiting many cancer cell lines proliferation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2064292-12-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114305. | |
| A1899 | A1899 is a potent and highly selective blocker of the K 2P channel TASK-1. A1899 has IC 50 values of 35.1 nM and 7 nM for TASK-1 channels expressed in oocytes and CHO cells, respectively. A1899 is also an I Kur blocker that can be used for the research of cardiovascular diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S20951. CAS No. 498577-46-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103067. | |
| A-196 | A-196 is a potent and selective inhibitor of SUV420H1 and SUV420H2 with IC50 values of 25 nM and 144 nM, respectively. A-196 inhibits SUV4-20 biochemically in a substrate-competitive manner. A-196 represents a first-in-class chemical probe of SUV4-20 to investigate the role of histone methyltransferases in genomic integrity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1982372-88-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100201. | |
| A-205804 | A-205804 is an orally bioavailable, potent and selective lead inhibitor of E-selectin and ICAM-1 expression, with an IC50 of 20 nM and 25 nM for E-selectin and ICAM-1, respectively. A-205804 can be used in the research of chronic inflammatory diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 251992-66-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-100226. | |
| A2764 dihydrochloride | A2764 dihydrochloride is a highly selective inhibitor of TRESK (TWIK-related spinal cord K + channel, K2P18.1), which has moderate inhibitory effects on TREK-1 and TALK-1. A2764 dihydrochloride is more sensitive to the activated mTRESK channels ( IC 50 =6.8 μM) than the basal current. A2764 dihydrochloride can lead to cell depolarization and increased excitability in native cells, it has the potential for probing the role of TRESK channel in migraine and nociception [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 861038-72-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-135809. | |
| A-286982 | A-286982 is a potent and allosteric LFA-1/ICAM-1 interaction inhibitor with IC 50 s of 44 nM and 35 nM in an LFA-1/ICAM-1 binding and LFA-1-mediated cellular adhesion assay, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 280749-17-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107587. | |
| A2A receptor antagonist 1 | A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A 2A receptor and A 1 receptor with K i values of 4 and 264 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPI-444 analog. CAS No. 443103-97-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102024. | |
| A2ti-1 | A2ti-1 is a selective and high-affinity annexin A2/S100A10 heterotetramer (A2t) inhibitor with an IC50 of 24 ?M[1]. A2ti-1 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. A2ti-1 prevents human papillomavirus type 16 (HPV16) infection[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 570390-00-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136465. | |
| A3334 | A3051 is a potent and orally active inhibtor of CXXC5-DVL extracted from patent WO2020079569, has an IC 50 of 63.06 nM. A3334 can be used for the research of high fat diet (HFD)-induced and methionine-choline deficient diet (MCD)-induced phenotypes such as obesity, diabetes, and NASH [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 854171-31-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-131448. | |
| A-350619 hydrochloride | A-350619 hydrochloride is a soluble guanylate cyclase ( sGC ) activator. A-350619 hydrochloride can be used in the study of erectile dysfunction [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1217201-17-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107548. | |
| A-366 | A-366 is a potent, highly selective, peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP (EHMT1), respectively. A-366 shows >1000-fold selectivity over 21 other methyltransferases. A-366 is also a potent, nanomolar inhibitor of the Spindlin1-H3K4me3-interaction (IC50=182.6 nM). A-366 displays high affinity at human histamine H3 receptor (Ki=17 nM) and shows subtype selectivity among subsets of the histaminergic and dopaminergic receptor families[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1527503-11-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12583. | |
| A-395 | A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2089148-72-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101512. | |
| A-3 hydrochloride | A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA ( K i =4.3 μM), casein kinase II ( K i =5.1 μM) and myosin light chain kinase (MLCK) ( K i =7.4 μM). A-3 hydrochloride also inhibits PKC and casein kinase I with K i values of 47 μM and 80 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 78957-85-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-125957. | |
| A 410099.1 | A 410099.1 is a BIRC inhibitor, with EC 50 values for BIRC2 , BIRC3 , BIRC4 , BIRC7 , and BIRC8 are 4.6, 9.2, 15.6, 19.9, and 93.9 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 762274-58-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-50685. | |
| A 419259 | A 419259 is a broad-spectrum pyrrolo-pyrimidine inhibitor, has high selectivity towards the Src family. A 419259 shows inhibitory effect for Src, Lck and Lyn with IC50 of 9 nM, <3 nM and <3 nM, respectively[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RK-20449. CAS No. 364042-47-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15764. | |
| A 419259 trihydrochloride | A 419259 trihydrochloride is a Src family kinases inhibitor with IC50s of 9 nM, 3 nM and 3 nM for Src, Lck and Lyn, respectively[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RK 20449 trihydrochloride. CAS No. 1435934-25-0. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15764A. | |
| A 438079 | A 438079 is a potent, and selective P2X 7 receptor antagonist with pIC 50 of 6.9. Uses: Scientific research. Group: Signaling pathways. CAS No. 899507-36-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15488. | |
| A 438079 hydrochloride | A 438079 (hydrochloride) is a potent, and selective P2X 7 receptor antagonist with pIC 50 of 6.9. Uses: Scientific research. Group: Signaling pathways. CAS No. 899431-18-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15488A. | |
| A-484954 | A-484954 is a highly selective eukaryotic elongationfactor-2 kinase(eEF2K) inhibitor, with an IC50 of 280 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 142557-61-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-110096. | |
| A-485 | A-485 is a potent and selective catalytic inhibitor of p300/CBP with IC50s of 9.8 nM and 2.6 nM for p300 and CBP histone acetyltransferase (HAT), respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1889279-16-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107455. | |
| A-582941 dihydrochloride | A-582941 dihydrochloride is a potent, selective and brain-penetrant partial agonist of α7 nAChR , with K i s of 10.8 and 16.7 nM in rat brain membranes and human frontal cortex, respectively. A-582941 dihydrochloride also binds to human 5-HT 3 receptor with a K i of 150 nM. A-582941 has the potential for cognitive deficits associated with various neurodegenerative and psychiatric disorders research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 848591-90-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-59201A. | |
| A-61603 | A-61603 is a selective α 1A -adrenergic receptor agonist [1]. A-61603 increases the frequency of spontaneous Ca 2+ transients in rat ventricular myocytes in vitro [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 107756-30-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101366. | |
| A-65186 | A-65186 is a CCK-A receptor antagonist with the activity of inhibiting CCK8-induced amylase secretion. A-65186 has high binding affinity for pancreatic CCK-A receptors, is more than 500 times more selective for CCK-A receptors than for CCK-B receptors, and can inhibit CCK8-induced amylase secretion. Uses: Scientific research. Group: Signaling pathways. CAS No. 119295-94-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-118194. | |
| A66 | A66 is a highly specific and selective p110α inhibitor with an IC 50 of 32 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1166227-08-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13261. | |
| A68930 hydrochloride | A68930 hydrochloride, as a dopamine D1 receptor agonist, can be used for the research of bronchiectasis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130465-39-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-103431. | |
| A-740003 | A-740003 is a potent, selective and competitive P2X7 receptor antagonist with IC50 values are 18 and 40 nM for rat and human P2X7 receptors, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 861393-28-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50697. | |
| A-769662 | A-769662 is a AMP-activated protein kinase (AMPK) activator. A-769662 inhibits the function of the 26S proteasome by an AMPK-independent mechanism and leads to cell cycle arrest. A-769662 directly stimulates partially purified rat liver AMPK (EC50 = 0.8 ?M) and inhibits fatty acid synthesis in primary rat hepatocytes (IC50 = 3.2 ?M). A-769662 can alleviate the symptoms of metabolic diseases such as type 2 diabetes[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 844499-71-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50662. | |
| A-770041 | A-770041 is a selective and orally active Src-family Lck inhibitor. A-770041 inhibits Lck with an IC50 value of 147 nM with the presence of 1 mM ATP. A-770041 shows 300-fold selective to Lck over Fyn, the other Src family kinase involved in T-cell signaling. A-770041 can be used for the research of acute rejection[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 869748-10-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11011. | |
| A-77636 hydrochloride | A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist ( pK i =7.40; K i =39.8 nM) with antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 145307-34-2. Pack Sizes: 5 mg. Product ID: HY-103416. | |
| A 779 | A 779 is a specific antagonist of G-protein coupled receptor (Mas receptor), which is an Ang1-7 receptor distinct from the classical AngII. Uses: Scientific research. Group: Peptides. CAS No. 159432-28-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-P0216. | |
| A-784168 | A-784168 is a potent and orally active inhibitor of vanilloid receptor type 1 ( TRPV1 ). Vanilloid receptor type 1 (TRPV1) is a ligand-gated nonselective cation channel that is considered to be an important integrator of various pain stimuli such as endogenous lipids, capsaicin, heat, and low pH. A-784168 has good CNS penetration [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 824982-41-4. Pack Sizes: 5 mg. Product ID: HY-108460. | |
| A-7 hydrochloride | A-7 hydrochloride (Ophobolin A) is a calmodulin antagonist and can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ophobolin A. CAS No. 79127-24-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100914. | |
| A-803467 | A-803467 is a potent and selective tetrodotoxin-resistant Nav1.8 sodium channel blocker (IC50=8 nM). A-803467 has shown significant anti-nociception in neuropathic and inflammatory pain models. A-803467 enhances the chemosensitivity of conventional anticancer agents through interaction with the ATP-binding cassette subfamily G member 2 (ABCG2) transporter[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 944261-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-11079. | |
| A-804598 | A-804598 is a CNS penetrant, competitive and selective P2X7 receptor antagonist with IC50s of 9 nM, 10 nM and 11 nM for mouse, rat and human P2X7 receptors, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1125758-85-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100483. | |
| A 83-01 | A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase , type I nodal receptor ALK4 and type I nodal receptor ALK7 , with IC 50 s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5 , ALK4 and ALK7 , respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 909910-43-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10432. | |
| A 83-01 sodium | A 83-01 sodium is a potent inhibitor of TGF-β type I receptor ALK5 kinase , ALK4 and ALK7 , with IC 50 s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5 , ALK4 and ALK7 , respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2828431-89-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10432A. | |
| A 85380 hydrochloride | A 85380 hydrochloride is a novel, high affinity neuronal nicotinic acetylcholine receptor ( nAChR ) agonist. A 85380 hydrochloride exhibits selectivity for the α4β2 nAChR subtypes. A 85380 hydrochloride has a broad-spectrum analgesic profile [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 174740-86-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-110131. | |
| A 922500 | A 922500 (DGAT-1 Inhibitor 4a) is a potent, selective, and orally bioavailable diacylglycerol acyltransferase 1 (DGAT-1) inhibitor with IC50s of 9 and 22 nM against human and mouse DGAT-1, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DGAT-1 Inhibitor 4a. CAS No. 959122-11-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10038. | |
| A939572 | A939572 is a potent, and orally bioavailable stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM and 37 nM for mSCD1 and hSCD1, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1032229-33-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50709. | |
| A-966492 | A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with K i of 1 nM and 1.5 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 934162-61-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-10614. | |
| A-967079 | A-967079 is a selective TRPA1 receptor antagonist with IC 50 s of 67 nM and 289 nM at human and rat TRPA1 receptors, respectively, and has good penetration into the CNS. Uses: Scientific research. Group: Signaling pathways. CAS No. 1170613-55-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108463. | |
| A-971432 | A-971432 is a potent, selective and orally active sphingosine-1-phosphate (S1P) receptor 5 agonist with IC 50 s of.362, >10, 0.006 μM for S1P1, S1P3, S1P5 respectively. A-971432 protects blood - brain barrier (BBB) homeostasis. A-971432 reverses age-related cognitive decline. A-971432 has the potential for the research of alzheimers disease or multiple sclerosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1240308-45-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-110291. | |
| AA147 | AA147 is a endoplasmic reticulum (ER) proteostasis regulator. AA147 promotes protection against oxidative damage in neuronal cells and prevents endothelial barrier dysfunction by activating ATF6 arm (selectively) of the unfolded protein response (UPR) and the NRF2 oxidative stress response. AA147 can rebalances XBP1s expression in vivo, and also induces survival motor neuron (SMN) expression and spinal motorneuron (MN) protection [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 393121-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124293. | |
| AA74-1 | AA74-1 is a potent and selective inhibitor of APEH. AA74-1 significantly increases T cells proliferation by blocking the APEH activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1361532-00-4. Pack Sizes: 1 mg. Product ID: HY-134932. | |
| AAA | AAA is a potent blocker of 20-Hydroxyeicosatetraenoic acid (20-HETE) receptor that binds directly to GPR75 and prevents the increases in intracellular Ca2+, IP-1 and ?-arrestin[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 500 ?g; 1 mg. Product ID: HY-160187. | |
| AACA | AACA is an inhibitor for sclerostin , that binds sclerostin on loop3 region with K d of 15.4 nM. AACA exhibits anti-osteoporosis activity through Wnt signaling pathway [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2515609-54-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163513. | |
| AACOCF3 | AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeant trifluoromethyl ketone analog of arachidonic acid. AACOCF3 is a potent and selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). AACOCF3 blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets. AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets. AACOCF3 has the potential for the research of cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Arachidonyl trifluoromethyl ketone. CAS No. 149301-79-1. Pack Sizes: 5 mg (28.05 mM * 500 μL in Ethanol); 10 mg (28.05 mM * 1 mL in Ethanol). Product ID: HY-108611. | |
| AAMU | AAMU (5-Acetylamino-6-amino-3-methyluracil) is the main metabolite of caffeine in the human body [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-Acetylamino-6-amino-3-methyluracil. CAS No. 19893-78-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-113118. | |
| AAPH | AAPH (2,2'-Azodiisobutyramidine dihydrochloride) has an effect of radical generation. AAPH induces oxidative stress and erythrocyte hemolysis [1]. AAPH decomposes at 37°C to generate an alkyl radical, is used as an initiator. In the presence of oxygen, these alkyl radicals will be converted to peroxyl radicals that can cause lipid peroxidation and loss of erythrocyte membrane integrity, which could ultimately lead to hemolysis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,2'-Azodiisobutyramidine dihydrochloride. CAS No. 2997-92-4. Pack Sizes: 1 g; 5 g. Product ID: HY-Y0525. | |
| AAZ-A 154 | AAZ-A 154 is a selective, competitive and non-hallucinogenic 5-HT2AR antagonist. AAZ-A 154 can promote neuronal growth and produce long-lasting beneficial behavioral effects in rodents [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2481740-94-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153015. | |
| AB21 hydrochloride | AB21 hydrochloride is a potent and selective S1R antagonist with K i s of 13, 102 nM for S1R and S2R. AB21 hydrochloride has the effect of reducing mechanical hypersensitivity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3026677-24-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149854B. | |
| AB-423 | AB-423 is an inhibitor of HBV capsid assembly, and potent inhibits HBV replication with EC 50 /EC 90 of 0.08-0.27 μM/0.33-1.32 μM in cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-DVR-23. CAS No. 1572510-80-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112142. | |
| AB-680 | AB-680 is a highly potent, reversible and selective inhibitor of CD73 (an ecto-nucleotidase), with a Ki of 4.9 pM for hCD73, displays >10,000-fold selectivity over related ecto-nucleotidases CD39. Anti-tumor activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2105904-82-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125286. | |
| AB-836 | AB-836 is an orally active HBV capsid inhibitor. AB-836 inhibits viral replication by interacting with HBV core protein [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2445597-31-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148348. | |
| Abacavir | Abacavir is an orally active and competitive nucleoside reverse transcriptase inhibitor. Abacavir can inhibits the replication of HIV. Abacavir shows anticancer activity in prostate cancer cell lines. Abacavir can trespass the blood-brain-barrier and suppresses telomerase activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 136470-78-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-17423. | |
| Abacavir sulfate | Abacavir sulfate (Abacavir Hemisulfate) is a competitive, orally active nucleoside reverse transcriptase inhibitor. Abacavir sulfate can inhibits the replication of HIV. Abacavir sulfate shows anticancer activity in prostate cancer cell lines. Abacavir sulfate can trespass the blood-brain-barrier and suppresses telomerase activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abacavir Hemisulfate; ABC sulfate. CAS No. 188062-50-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17423A. | |
| Abaecin | Abaecin is an antibacterial response peptide. Abaecin shows specific activity against an Apidaecin-resistant Xanthomonas strain [1]. Uses: Scientific research. Group: Peptides. CAS No. 123997-18-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5714. | |
| Abafungin | Abafungin, a antifungal agent, inhibitis the transmethylation at the C-24 position of the sterol side chain, catalyzed by the enzyme sterol-C-24-methyltransferase. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-W-6341. CAS No. 129639-79-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-119847. | |
| Abagovomab | Abagovomab (Anti-Human CA-125 Recombinant Antibody) is a murine monoclonal anti-idiotypic antibody, against the tumor-associated antigen, CA-125. Abagovomab is generated by a mouse hybridoma, can imitate the human TAA, CA-125. Abagovomab can elicit humoral and cellular immune responses against ovarian cancer (oc) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human CA-125 Recombinant Antibody. CAS No. 792921-10-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99276. | |
| Abaloparatide | Abaloparatide (BA 058) is a parathyroid hormone receptor 1 (PTHR1) analog. Abaloparatide also is a selective PTHR1 activator. Abaloparatide enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide enhances bone formation and cortical structure in mice. Abaloparatide has the potential for the research of osteoporosis [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: BA 058; BIM 44058. CAS No. 247062-33-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108742. | |
| Abaloparatide TFA | Abaloparatide TFA (BA 058 TFA) is a parathyroid hormone receptor 1 (PTHR1) analogue. Abaloparatide TFA also is a selective PTHR1 activator. Abaloparatide TFA enhances Gs/cAMP signaling and ?-arrestin recruitment. Abaloparatide TFA enhances bone formation and cortical structure in mice. Abaloparatide TFA has the potential for the research of osteoporosis[1][2]. Uses: Scientific research. Group: Peptides. Alternative Names: BA 058 TFA; BIM 44058 TFA. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-108742A. | |
| Abametapir | Abametapir is a metalloproteinase (MMP) inhibitor which is able to target metalloproteinases critical to egg hatching and louse development. Abametapir can inhibit hatching of both head and body louse [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1762-34-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-W004546. | |
| Abarelix | Abarelix (R3827; PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer treatment. Uses: Scientific research. Group: Peptides. Alternative Names: R3827; PPI 149. CAS No. 183552-38-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13534. | |
| Abarelix Acetate | Abarelix Acetate (PPI 149 Acetate; R 3827 Acetate) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer research [1]. Uses: Scientific research. Group: Peptides. Alternative Names: PPI 149 Acetate; R 3827 Acetate. CAS No. 547741-72-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13534A. | |
| Abatacept | Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains) [1]. Abatacept is a selective T-cell co-stimulation modulator and a protein agent for the autoimmune diseases [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CTLA4lg; BMS-188667. CAS No. 332348-12-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108829. | |
| Abatacept (powder) | Abatacept (CTLA4lg; BMS-188667) powder is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). Abatacept powder is a selective T-cell co-stimulation modulator and a protein agent for the autoimmune diseases [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CTLA4lg (powder); BMS-188667 (powder). CAS No. 332348-12-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108829A. | |
| ABBV-467 | ABBV-467 is a selective MCL-1 inhibitor (Ki: <0.01 nM). ABBV-467 induces apoptosis. ABBV-467 induces cancer cell death and inhibits tumor growth in models of hematological malignancies, such as multiple myeloma[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2287186-66-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-149672. | |
| ABBV-744 | ABBV-744 is a first-in-class, orally active and selective inhibitor of the BDII domain of BET family proteins with IC50 values ranging from 4 to 18 nM for BRD2, BRD3, BRD4 and BRDT. ABBV-744 is primarily metabolized by CYP3A4 with agent-like properties enable the investigation of its antitumor efficacy and tolerability[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2138861-99-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112090. | |
| ABBV-CLS-7262 | ABBV-CLS-7262 is modulates the integrated stress response (ISR) for inhibition of ISR-related diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fosigotifator THAM sodium. CAS No. 2945073-88-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-153399A. | |
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