MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
×
Product
Description
Suppliers Website
AK-1
AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor, with an IC 50 of 12.5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 330461-64-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101465.
AK-7
AK-7 is a selective cell- and brain-permeable SIRT2 inhibitor, with an IC 50 of 15.5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 420831-40-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16691.
AKBA
AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. Uses: Scientific research. Group: Natural products. Alternative Names: Acetyl-11-keto-β-boswellic acid. CAS No. 67416-61-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0892.
AKBA (Standard)
AKBA (Standard) is the analytical standard of AKBA. This product is intended for research and analytical applications. AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. Uses: Scientific research. Group: Natural products. CAS No. 67416-61-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0892R.
AKT-IN-23
AKT-IN-23 is an AKT inhibitor. AKT-IN-23 can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1226801-23-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161704.
AKT inhibitor IV
Akt inhibitor-IV (AKTIV) acts as a PI3K-Akt inhibitor at the E isomer (HY-14971), with potent cytotoxicity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKTIV. CAS No. 681281-88-9. Pack Sizes: 1 mg. Product ID: HY-14971A.
AKT Kinase Inhibitor
AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 842148-40-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-10249A.
AKT Kinase Inhibitor hydrochloride
AKT Kinase Inhibitor hydrochloride is an Akt kinase inhibitor with anti-tumor activity [1]. AKT Kinase Inhibitor (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 3026697-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10249D.
AKV-9
AKV-9 is the inhibitor for mutated Cu/Zn superoxide dismutase ( SOD1 ), that inhibits SOD1-induced protein aggregation and exhibits protective efficacy against SOD1-induced cytotoxicity in PC-12 with an EC 50 of 0.3 μM. AKV-9 ameliorates amyotrophic lateral sclerosis in mouse models and extends their lifespan [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1307262-15-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169904.
AL-9
AL-9 is a inhibitor of PI4KIIIα, with the IC 50 of 0.57 μM, that can inhibit HCV replication [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 869218-90-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118525.
[Ala11,D-Leu15]-Orexin B(human)
[Ala11,D-Leu15]-Orexin B(human) is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B(human) shows a 400-fold selectivity for the OX2 ( EC 50 =0.13 nM) over OX1 (52 nM) [1]. Uses: Scientific research. Group: Peptides. CAS No. 532932-99-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1340.
Ala-D-γ-Glu-Lys-D-Ala-D-Ala
Ala-D-γ-Glu-Lys-D-Ala-D-Ala is the pentapeptide tail of the peptidoglycan precursor UDPMurNAc-l-Ala-γ-d-Glu-l-Lys(Gly)(5)-d-Ala-d-Ala [1]. Uses: Scientific research. Group: Peptides. CAS No. 2614-55-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P5919.
Alagebrium chloride
Alagebrium chloride (ALT711) is an advanced glycation end product ( AGE ) inhibitor. Uses: Scientific research. Group: Natural products. Alternative Names: ALT711. CAS No. 341028-37-3. Pack Sizes: 10 mM * 1 mL; 200 mg. Product ID: HY-106024B.
Alamethicin
Alamethicin is a linear 20-amino acid antibiotic , which can induce voltage-gated conductance in model and cell membranes. Alamethicin exhibits antimicrobial activity against Gram-positive bacteria, but not Gram-negative bacteria. Alamethicin can form an amphipathic α-helical structure in biological membranes [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 27061-78-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6708.
Alamifovir
Alamifovir (LY582563; MCC-478), a purine nucleotide analogue proagent, shows potent activity against wild type and lamivudine resistant hepatitis B virus (HBV). Alamifovir has high activity against HBV replication and sustained antiviral effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY582563; MCC-478. CAS No. 193681-12-8. Pack Sizes: 1 mg. Product ID: HY-119691.
Alanine-2,3,3,3-d4
Alanine-2,3,3,3-d4 is the deuterium labeled Alanine-2,3,3,3[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 53795-92-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W244382.
Alanine aminotransferase, Porcine heart
Alanine aminotransferase, Porcine heart is a pyridoxal enzyme that catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9000-86-6. Pack Sizes: 200 U. Product ID: HY-P2985.
Alanine dehydrogenase, expressed in E. coli
Alanine dehydrogenase, expressed in E. coli is a microbial enzyme that catalyzes a reversible conversion of L-alanine to pyruvate [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9029-6-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2854.
Alantolactone
Alantolactone is a selective STAT3 inhibitor, with potent anticancer activity. Alantolactone induces apoptosis in cancer [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Alantolactone; Alant camphor; Inula camphor. CAS No. 546-43-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0038.
Alarelin Acetate
Alarelin acetate is a synthetic GnRH agonist. Uses: Scientific research. Group: Peptides. Alternative Names: Alarelin. CAS No. 79561-22-1. Pack Sizes: 5 mg; 10 mg; 100 mg. Product ID: HY-17405.
Albendazole
Albendazole (SKF-62979) is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity, is used for the research of gastrointestinal parasites in humans and animals. Albendazole induces apoptosis and autophagy in cancer cells. Albendazole also inhibits tubulin polymerization and HIF-1α , VEGF expression, has antioxidant activity, and inhibits the glycolytic process in cancer cells [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF-62979. CAS No. 54965-21-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0223.
Albendazole (Standard)
Albendazole (Standard) is the analytical standard of Albendazole. This product is intended for research and analytical applications. Albendazole (SKF-62979) is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity, is used for the research of gastrointestinal parasites in humans and animals. Albendazole induces apoptosis and autophagy in cancer cells. Albendazole also inhibits tubulin polymerization and HIF-1α, VEGF expression, has antioxidant activity, and inhibits the glycolytic process in cancer cells [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54965-21-8. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0223R.
Albendazole sulfoxide
Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ricobendazole; Albendazole oxide. CAS No. 54029-12-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-12785.
ALC-0159
ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1849616-42-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138300.
ALC-0315
ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2036272-55-4. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-138170.
Alcaftadine
Alcaftadine (R89674) is a histamine H1 receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis. Alcaftadine is a broad-spectrum antihistamine displaying a high affinity for histamine H1 and H2 receptors and a lower affinity for H4 receptors. Alcaftadine also exhibits modulatory action on immune cell recruitment and mast cell stabilizing effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R89674. CAS No. 147084-10-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17039.
Alcian Blue 8GX
Alcian Blue 8GX is a commonly used phthalocyanine dye that binds to glycoproteins and glycosaminoglycans. Alcian Blue 8GX has a wide range of applications in biological staining, including proteins in brain tumors and DNA in cells and tissues [1] [2] [3] [4]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 33864-99-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-D0001.
Alclometasone dipropionate
Alclometasone dipropionate (Sch 22219) is a steroid compound. Alclometasone dipropionate can be used for the research of dermatitis and skin itch [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sch 22219. CAS No. 66734-13-2. Pack Sizes: 2.5 mg. Product ID: HY-106566.
Alcohol dehydrogenase, Saccharomyces cerevisiae
Alcohol dehydrogenase, Saccharomyces cerevisiae is a dimeric protein in the cytosol of cells. Alcohol dehydrogenase, the key enzyme for alcohol consumption in the body, is the highest expressed in the liver and participates in the detoxification mechanism of environmental alcohol [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 1.1.1.1. CAS No. 9031-72-5. Pack Sizes: 25 KU. Product ID: HY-P2740.
Alcohol oxidase
Alcohol oxidase is a functional enzyme of methanol utilization pathway and can be isolated from yeast peroxisome [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AO; AOX. CAS No. 9073-63-6. Pack Sizes: 50 U; 250 U. Product ID: HY-P2756.
Alda-1
Alda-1 is a potent and selective ALDH2 agonist, which activates wild-type ALDH2 and restores near wild-type activity to ALDH2*2. Uses: Scientific research. Group: Signaling pathways. CAS No. 349438-38-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-18936.
Aldafermin
Aldafermin (NGM282) is an analog of fibroblast growth factor 19. Aldafermin can be used for the research of nonalcoholic steatohepatitis (NASH) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: NGM282. CAS No. 1616639-03-2. Pack Sizes: 500 μg; 1 mg. Product ID: HY-P99428.
ALDH
ALDH (Aldehyde dehydrogenase (NAD(P))) catalyzes the oxidation of aldehydes into their corresponding carboxylic acids with the concomitant reduction of the cofactor NAD(P) into NAD(P)H, is often used in biochemical studies. The ALDHs are one of many enzyme systems the body utilizes to alleviate aldehyde stress [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aldehyde dehydrogenase (NAD(P)). CAS No. 9028-88-0. Pack Sizes: 25 U. Product ID: HY-P2947.
Aldicarb sulfone
Aldicarb sulfone(Temik sulfone) is a carbamate insecticide; is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse. Uses: Scientific research. Group: Signaling pathways. CAS No. 1646-88-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-17530.
Aldolase, Rabbit muscle
Aldolase, Rabbit muscle is a glycolytic enzyme and a component of the VATPase complex. Aldolase causes fructose 1, 6-diphosphate to decompose into dihydroxyacetone and glyceraldehyde 3-phosphate [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fructose-diphosphate aldolase. CAS No. 9024-52-6. Pack Sizes: 100 U; 500 U. Product ID: HY-P2726.
Aldosterone
Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 52-39-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-113313.
Aldoxorubicin
Aldoxorubicin (INNO-206) is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), which is released from albumin under acidic conditions. Aldoxorubicin (INNO-206) has potent antitumor activities in various cancer cell lines and in murine tumor models. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INNO-206; DOXO-EMCH. CAS No. 1361644-26-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16261.
Alectinib
Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC 50 of 1.9 nM and a K d value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC 50 s of 1 nM and 3.5 nM, respectively [1]. Alectinib demonstrates effective central nervous system (CNS) penetration [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CH5424802; RO5424802; RG7853. CAS No. 1256580-46-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13011.
Alectinib Hydrochloride
Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC 50 of 1.9 nM and a K d value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC 50 s of 1 nM and 3.5 nM, respectively [1]. Alectinib demonstrates effective central nervous system (CNS) penetration [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride. CAS No. 1256589-74-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13011A.
Alefacept
Alefacept (BG 9273) is a human lymphocyte function-associated antigen 3/immunoglobulin 1 fusion protein. Alefacept can be used for the research of chronic plaque psoriasis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BG 9273; Human LFA 3IgG fusion protein; LFA 3TIP. CAS No. 222535-22-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99429.
Aleglitazar
Aleglitazar (R1439) is a potent dual PPARα/γ agonist, with IC 50 s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for the research of type II diabetes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R1439; RO0728804. CAS No. 475479-34-6. Pack Sizes: 10 mM * 1 mL; 1 mg. Product ID: HY-14728.
Alemtuzumab
Alemtuzumab (Campath-IH) is a humanized monoclonal antibody against CD52. Alemtuzumab does not cross-react with murine CD52. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes. Alemtuzumab is capable of complement-dependent cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC), as well as induction of apoptosis. Alemtuzumab has the potential for B-cell chronic lymphocytic leukaemia research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Campath-IH. CAS No. 216503-57-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P9948.
Alendronate sodium
Alendronate sodium is an orally active nitrogen-containing bisphosphonate. Alendronate sodium potently inhibits bone resorption. Alendronate sodium is used for the research of postmenopausal osteoporosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Alendronic acid monosodium salt. CAS No. 129318-43-0. Pack Sizes: 100 mg; 500 mg. Product ID: HY-108685.
Alendronate sodium hydrate
Alendronate (sodium hydrate) is a farnesyl diphosphate synthase inhibitor with IC 50 of 460 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Alendronate; MK 217; G-704650 Adronat. CAS No. 121268-17-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-11101.
Alendronic acid
Alendronic acid, a bisphosphonate, is a farnesyl diphosphate synthase (FDPS) inhibitor. Alendronic acid inhibits osteoclast-mediated bone resorption. Alendronic acid shows efficacy in postmenopausal osteoporosis, malignant hypercalcemia and Pagets disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66376-36-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0631.
Aleuritic acid
Aleuritic acid ((±)-erythro-Aleuritic acid) is a major ingredient in Croton crassifolius Geisel. and used in the perfumery industry [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-erythro-Aleuritic acid; α-Aleuritic acid. CAS No. 533-87-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg. Product ID: HY-N7076.
Alexidine dihydrochloride
Alexidine dihydrochloride is an anticancer agent that targets a mitochondrial tyrosine phosphatase, PTPMT1 , in mammalian cells and causes mitochondrial apoptosis. Alexidine dihydrochloride has antifungal and antibiofilm activity against a diverse range of fungal pathogens [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1715-30-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-108547.
Alfacalcidol
Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-hydroxycholecalciferol; 1.alpha.-Hydroxyvitamin D3. CAS No. 41294-56-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10003.
ALFA-tag
ALFA-tag is a small and stable α-helical structure composed of 15 amino acids. ALFA-tag is highly hydrophilic and can be placed at the N-terminus, C-terminus, or between two independently folded domains of the target protein without affecting the function of the protein. ALFA-tag is widely used as an epitope tag and is used for the detection and manipulation of proteins in living cells [1]. Uses: Scientific research. Group: Peptides. CAS No. 2413353-86-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P10531.
Alfuzosin
Alfuzosin (SL 77499-10) is an orally active, selective and competitive α1-adrenoceptor antagonist. Alfuzosin relaxes the muscles of the prostate and bladder neck, aiding in urination. Alfuzosin can be used in study of benign prostatic hyperplasia (BPH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SL 77499. CAS No. 81403-80-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0192.
Alfuzosin-d3
Alfuzosin-d 3 is deuterium labeled Alfuzosin. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: SL 77499-d3. CAS No. 1006724-55-5. Pack Sizes: 1 mg. Product ID: HY-B0192S2.
Alfuzosin hydrochloride
Alfuzosin (SL 77499-10) hydrochloride is an orally active, selective and competitive α1-adrenoceptor antagonist. Alfuzosin hydrochloride relaxes the muscles of the prostate and bladder neck, aiding in urination. Alfuzosin hydrochloride can be used in study of benign prostatic hyperplasia (BPH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SL 77499-10. CAS No. 81403-68-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0192A.
Alginate lyase
Alginate lyase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 9024-15-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2835.
Alginic acid
Alginic acid is a natural polysaccharide, which has been widely concerned and applied due to its excellent water solubility, film formation, biodegradability and biocompatibility. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Alginic acid has an inhibitory effect on histamine release. Anti-anaphylactic and anti-inflammatory properties [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 9005-32-7. Pack Sizes: 50 g; 100 g. Product ID: HY-W127758.
Alinidine hydrobromide
Alinidine (St-567) hydrobromide is a specific bradycardic agent. Alinidine hydrobromide reduces the slope of the diastolic depolarization in sinoatrial tissue and Purkinje fibers. Alinidine hydrobromide shows antiischemic and antiarrhythmic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: St-567 hydrobromide. CAS No. 71306-36-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-106688A.
Alirocumab
Alirocumab is an anti-PCSK9 human monoclonal antibody. Alirocumab inhibits PCSK9. Alirocumab reduces NLRP3 inflammasome , regulates Nrf2/HO-1 , HMGB1/NF-κB and Fractalkine/CX3CR1. Alirocumab increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood. Alirocumab improves atherosclerosis and inflammation [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN 727; SAR 236553. CAS No. 1245916-14-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9928.
Alirocumab (anti-PCSK9)
Alirocumab (anti-PCSK9) is an anti-PCSK9 human monoclonal antibody. Alirocumab (anti-PCSK9) inhibits PCSK9. Alirocumab (anti-PCSK9) reduces NLRP3 inflammasome , regulates Nrf2/HO-1 , HMGB1/NF-κB and Fractalkine/CX3CR1. Alirocumab (anti-PCSK9) increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood. Alirocumab (anti-PCSK9) improves atherosclerosis and inflammation [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN 727(anti-PCSK9); SAR 236553(anti-PCSK9). CAS No. 1245916-14-6. Pack Sizes: 1 mg; 2 mg; 5 mg. Product ID: HY-P9928A.
Alisertib
Alisertib (MLN 8237) is an orally active and selective Aurora A kinase inhibitor ( IC 50 =1.2 nM), which binds to Aurora A kinase resulting in mitotic spindle abnormalities, mitotic accumulation. Alisertib (MLN 8237) induces apoptosis and autophagy through targeting the AKT/mTOR/AMPK/p38 pathway in leukemic cells. Antitumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN 8237. CAS No. 1028486-01-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10971.
Aliskiren
Aliskiren is an orally active, highly potent and selective renin inhibitor, with IC 50 of 1.5 nM. Aliskiren can be used for the research of hypertension, cardiovascular diseases and cancer cachexia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 60536; CGP60536B; SPP 100. CAS No. 173334-57-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12176.
Aliskiren hemifumarate
Aliskiren (CGP 60536; CGP60536B; SPP 100) hemifumarate is an orally active and selective renin inhibitor, with IC 50 of 1.5 nM. Aliskiren hemifumarate can be used for the research of hypertension, cardiovascular diseases and cancer cachexia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 60536 hemifumarate; CGP60536B hemifumarate; SPP 100 hemifumarate. CAS No. 173334-58-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12177.
Alitame
Alitame is a high-intensity sweetener formed from the amino acids L-aspartic acid and D-alanine, and an amine derived from thietane [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80863-62-3. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg. Product ID: HY-129847.
Alizapride hydrochloride
Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride also used in human digestive disorders [1] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 59338-87-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-A0125A.
Alizarin
Alizarin is a natural dye. Alizarin can be extracted from the roots of madder plant. Alizarin activates AMPK and VEGFR2/eNOS pathway. Alizarin regulates PI3K/Akt and inhibits NF-κB pathway. Alizarin enhances CYP1A1 enzyme activity. Alizarin has protective effects on hypertension and vascular endothelial dysfunction. Alizarin has anti-tumor activity against multiple cancers including pancreatic cancer, breast cancer, osteosarcoma and liver cancer. Alizarin has been widely used as a pigment in textile fabrics and paintings [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. CAS No. 72-48-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N0563.
Alizarin complexone
Alizarin complexone is a calcium-tracer and a chelating agent. Alizarin complexone is Rous-associated virus 2 reverse transcriptase (RAV-2 RT) inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3952-78-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-121075.
Alizarin cyanin green F
Alizarin cyanin green F is an alizarin dye that reacts with calcium possibly via sulfonic acid and/or OH groups. Uses: Scientific research. Group: Fluorescent dye. CAS No. 4403-90-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1175.
Alizarin Red S sodium
Alizarin Red S sodium is an anthraquinone derivative dye. When combined with cations such as calcium ions, the functional group of Alizarin Red S sodium can form a coordination bond with the cation through the oxygen atom to show orange-red fluorescence. Alizarin Red S sodium can be used for screening of calcium compounds in synovial fluid and detecting osteoblast differentiation, and can also be used for bone staining in mice. Excitation/emission wavelength: 500/570 nm [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: ARS sodium. CAS No. 130-22-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-120601.
Alkaline phosphatase, Bovine intestine
Alkaline phosphatase, Bovine intestine (Apase) is a membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase can be used in molecular biology and enzyme-free analysis. Inhibition of tissue nonspecific alkaline phosphatase can block intracellular lipid accumulation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Apase. CAS No. 9001-78-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2818.
ALKBH5-IN-3
ALKBH5-IN-3 (Compound 20m) is a potent and selective ALKBH5 inhibitor, with an IC 50 of 21 nM. ALKBH5-IN-3 could efficiently stabilize ALKBH5 in HepG2 cells and increase m6A level in intact cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1505579-77-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-165422.
Alkyne Cholesterol
Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an alkyne group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1631985-09-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-151705.
Alkyne-PEG4-maleimide
Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Alkyne-PEG4-maleimide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1609651-90-2. Pack Sizes: 100 mg. Product ID: HY-133399.