MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Alectinib | Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC 50 of 1.9 nM and a K d value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC 50 s of 1 nM and 3.5 nM, respectively [1]. Alectinib demonstrates effective central nervous system (CNS) penetration [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CH5424802; RO5424802; RG7853. CAS No. 1256580-46-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13011. |  |
| Alectinib Hydrochloride | Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with an IC 50 of 1.9 nM and a K d value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC 50 s of 1 nM and 3.5 nM, respectively [1]. Alectinib demonstrates effective central nervous system (CNS) penetration [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride. CAS No. 1256589-74-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13011A. | |
| Alefacept | Alefacept (BG 9273) is a human lymphocyte function-associated antigen 3/immunoglobulin 1 fusion protein. Alefacept can be used for the research of chronic plaque psoriasis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BG 9273; Human LFA 3IgG fusion protein; LFA 3TIP. CAS No. 222535-22-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99429. | |
| Aleglitazar | Aleglitazar (R1439) is a potent dual PPARα/γ agonist, with IC 50 s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for the research of type II diabetes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R1439; RO0728804. CAS No. 475479-34-6. Pack Sizes: 10 mM * 1 mL; 1 mg. Product ID: HY-14728. | |
| Alemtuzumab | Alemtuzumab (Campath-IH) is a humanized monoclonal antibody against CD52. Alemtuzumab does not cross-react with murine CD52. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes. Alemtuzumab is capable of complement-dependent cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC), as well as induction of apoptosis. Alemtuzumab has the potential for B-cell chronic lymphocytic leukaemia research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Campath-IH. CAS No. 216503-57-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P9948. | |
| Alendronate sodium | Alendronate sodium is an orally active nitrogen-containing bisphosphonate. Alendronate sodium potently inhibits bone resorption. Alendronate sodium is used for the research of postmenopausal osteoporosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Alendronic acid monosodium salt. CAS No. 129318-43-0. Pack Sizes: 100 mg; 500 mg. Product ID: HY-108685. | |
| Alendronate sodium hydrate | Alendronate (sodium hydrate) is a farnesyl diphosphate synthase inhibitor with IC 50 of 460 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Alendronate; MK 217; G-704650 Adronat. CAS No. 121268-17-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-11101. | |
| Alendronic acid | Alendronic acid, a bisphosphonate, is a farnesyl diphosphate synthase (FDPS) inhibitor. Alendronic acid inhibits osteoclast-mediated bone resorption. Alendronic acid shows efficacy in postmenopausal osteoporosis, malignant hypercalcemia and Pagets disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66376-36-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0631. | |
| Aleniglipron | Aleniglipron (compound 121a) (GSBR-1290) is a GLP-1 agonist with an EC50 value of less than 0.1 nM in the HDB cell line in a cAMP stimulation assay[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSBR-1290. CAS No. 2685823-26-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160734. | |
| Aleuritic acid | Aleuritic acid ((±)-erythro-Aleuritic acid) is a major ingredient in Croton crassifolius Geisel. and used in the perfumery industry [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-erythro-Aleuritic acid; α-Aleuritic acid. CAS No. 533-87-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg. Product ID: HY-N7076. | |
| Alexa fluor 647 NHS ester TEA | Alexa fluor 647 NHS ester TEA can be used to label Alexa fluor 647 to the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D2096A. | |
| Alexidine dihydrochloride | Alexidine dihydrochloride is an anticancer agent that targets a mitochondrial tyrosine phosphatase, PTPMT1 , in mammalian cells and causes mitochondrial apoptosis. Alexidine dihydrochloride has antifungal and antibiofilm activity against a diverse range of fungal pathogens [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1715-30-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-108547. | |
| Alfacalcidol | Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-hydroxycholecalciferol; 1.alpha.-Hydroxyvitamin D3. CAS No. 41294-56-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10003. | |
| ALFA-tag | ALFA-tag is a small and stable α-helical structure composed of 15 amino acids. ALFA-tag is highly hydrophilic and can be placed at the N-terminus, C-terminus, or between two independently folded domains of the target protein without affecting the function of the protein. ALFA-tag is widely used as an epitope tag and is used for the detection and manipulation of proteins in living cells [1]. Uses: Scientific research. Group: Peptides. CAS No. 2413353-86-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P10531. | |
| Alfuzosin | Alfuzosin (SL 77499-10) is an orally active, selective and competitive α1-adrenoceptor antagonist. Alfuzosin relaxes the muscles of the prostate and bladder neck, aiding in urination. Alfuzosin can be used in study of benign prostatic hyperplasia (BPH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SL 77499. CAS No. 81403-80-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0192. | |
| Alfuzosin-d3 | Alfuzosin-d 3 is deuterium labeled Alfuzosin. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: SL 77499-d3. CAS No. 1006724-55-5. Pack Sizes: 1 mg. Product ID: HY-B0192S2. | |
| Alfuzosin hydrochloride | Alfuzosin (SL 77499-10) hydrochloride is an orally active, selective and competitive α1-adrenoceptor antagonist. Alfuzosin hydrochloride relaxes the muscles of the prostate and bladder neck, aiding in urination. Alfuzosin hydrochloride can be used in study of benign prostatic hyperplasia (BPH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SL 77499-10. CAS No. 81403-68-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0192A. | |
| Alginate lyase | Alginate lyase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 9024-15-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2835. | |
| Alginic acid | Alginic acid is a natural polysaccharide, which has been widely concerned and applied due to its excellent water solubility, film formation, biodegradability and biocompatibility. Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries. Alginic acid has an inhibitory effect on histamine release. Anti-anaphylactic and anti-inflammatory properties [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 9005-32-7. Pack Sizes: 50 g; 100 g. Product ID: HY-W127758. | |
| Alinidine hydrobromide | Alinidine (St-567) hydrobromide is a specific bradycardic agent. Alinidine hydrobromide reduces the slope of the diastolic depolarization in sinoatrial tissue and Purkinje fibers. Alinidine hydrobromide shows antiischemic and antiarrhythmic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: St-567 hydrobromide. CAS No. 71306-36-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-106688A. | |
| Alirocumab | Alirocumab is an anti-PCSK9 human monoclonal antibody. Alirocumab inhibits PCSK9. Alirocumab reduces NLRP3 inflammasome , regulates Nrf2/HO-1 , HMGB1/NF-κB and Fractalkine/CX3CR1. Alirocumab increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood. Alirocumab improves atherosclerosis and inflammation [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN 727; SAR 236553. CAS No. 1245916-14-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9928. | |
| Alirocumab (anti-PCSK9) | Alirocumab (anti-PCSK9) is an anti-PCSK9 human monoclonal antibody. Alirocumab (anti-PCSK9) inhibits PCSK9. Alirocumab (anti-PCSK9) reduces NLRP3 inflammasome , regulates Nrf2/HO-1 , HMGB1/NF-κB and Fractalkine/CX3CR1. Alirocumab (anti-PCSK9) increases the ability of the liver to bind LDL-cholesterol (LDL-C) and reduces levels of LDL-C in blood. Alirocumab (anti-PCSK9) improves atherosclerosis and inflammation [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN 727(anti-PCSK9); SAR 236553(anti-PCSK9). CAS No. 1245916-14-6. Pack Sizes: 1 mg; 2 mg; 5 mg. Product ID: HY-P9928A. | |
| Alisertib | Alisertib (MLN 8237) is an orally active and selective Aurora A kinase inhibitor ( IC 50 =1.2 nM), which binds to Aurora A kinase resulting in mitotic spindle abnormalities, mitotic accumulation. Alisertib (MLN 8237) induces apoptosis and autophagy through targeting the AKT/mTOR/AMPK/p38 pathway in leukemic cells. Antitumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN 8237. CAS No. 1028486-01-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10971. | |
| Aliskiren | Aliskiren is an orally active, highly potent and selective renin inhibitor, with IC 50 of 1.5 nM. Aliskiren can be used for the research of hypertension, cardiovascular diseases and cancer cachexia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 60536; CGP60536B; SPP 100. CAS No. 173334-57-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12176. | |
| Aliskiren hemifumarate | Aliskiren (CGP 60536; CGP60536B; SPP 100) hemifumarate is an orally active and selective renin inhibitor, with IC 50 of 1.5 nM. Aliskiren hemifumarate can be used for the research of hypertension, cardiovascular diseases and cancer cachexia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 60536 hemifumarate; CGP60536B hemifumarate; SPP 100 hemifumarate. CAS No. 173334-58-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12177. | |
| Alisporivir | Alisporivir (Debio-025) is a cyclophilin inhibitor molecule with potent anti-hepatitis C virus (HCV) activity. Uses: Scientific research. Group: Peptides. Alternative Names: Debio-025; DEB-025. CAS No. 254435-95-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12559. | |
| Alitame | Alitame is a high-intensity sweetener formed from the amino acids L-aspartic acid and D-alanine, and an amine derived from thietane [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80863-62-3. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg. Product ID: HY-129847. | |
| Alizapride hydrochloride | Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride also used in human digestive disorders [1] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 59338-87-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-A0125A. | |
| Alizarin | Alizarin is a natural dye. Alizarin can be extracted from the roots of madder plant. Alizarin activates AMPK and VEGFR2/eNOS pathway. Alizarin regulates PI3K/Akt and inhibits NF-κB pathway. Alizarin enhances CYP1A1 enzyme activity. Alizarin has protective effects on hypertension and vascular endothelial dysfunction. Alizarin has anti-tumor activity against multiple cancers including pancreatic cancer, breast cancer, osteosarcoma and liver cancer. Alizarin has been widely used as a pigment in textile fabrics and paintings [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. CAS No. 72-48-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N0563. | |
| Alizarin complexone | Alizarin complexone is a calcium-tracer and a chelating agent. Alizarin complexone is Rous-associated virus 2 reverse transcriptase (RAV-2 RT) inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3952-78-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-121075. | |
| Alizarin cyanin green F | Alizarin cyanin green F is an alizarin dye that reacts with calcium possibly via sulfonic acid and/or OH groups. Uses: Scientific research. Group: Fluorescent dye. CAS No. 4403-90-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1175. | |
| Alizarin Red S sodium | Alizarin Red S sodium is an anthraquinone derivative dye. When combined with cations such as calcium ions, the functional group of Alizarin Red S sodium can form a coordination bond with the cation through the oxygen atom to show orange-red fluorescence. Alizarin Red S sodium can be used for screening of calcium compounds in synovial fluid and detecting osteoblast differentiation, and can also be used for bone staining in mice. Excitation/emission wavelength: 500/570 nm [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: ARS sodium. CAS No. 130-22-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-120601. | |
| Alkaline phosphatase, Bovine intestine | Alkaline phosphatase, Bovine intestine (Apase) is a membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase can be used in molecular biology and enzyme-free analysis. Inhibition of tissue nonspecific alkaline phosphatase can block intracellular lipid accumulation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Apase. CAS No. 9001-78-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2818. | |
| ALKBH1-IN-1 | ALKBH1-IN-1 (Compound 13h) is a selective ALKBH1 inhibitor, with an IC50 of 0.026 ?M and 1.39 ?M in the fluorescence polarization and enzyme activity assay, respectively. ALKBH1-IN-1 can modulate the level of DNA 6mA modifications. ALKBH1-IN-1 can be used to study the functions of ALKBH1 and DNA 6mA[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163385. | |
| ALKBH5-IN-3 | ALKBH5-IN-3 (Compound 20m) is a potent and selective ALKBH5 inhibitor, with an IC 50 of 21 nM. ALKBH5-IN-3 could efficiently stabilize ALKBH5 in HepG2 cells and increase m6A level in intact cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1505579-77-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-165422. | |
| Alkyne Cholesterol | Alkyne Cholesterol, a modified lipid, is a click chemistry reagent containing an alkyne group. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents in the presence of a copper (Cu)-containing catalyst. Alkyne Cholesterol can be used for tracking cellular cholesterol metabolism and localization [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1631985-09-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-151705. | |
| Alkyne-PEG4-maleimide | Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Alkyne-PEG4-maleimide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1609651-90-2. Pack Sizes: 100 mg. Product ID: HY-133399. | |
| Alkyne-phenol | Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins[1]. Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Alkyne tyramide; Alk-Ph. CAS No. 1694495-59-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-131442. | |
| Alkynyl myristic acid | Alkynyl myristic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Alkynyl myristic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 82909-47-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140335. | |
| Alkynyl Palmitic Acid | Alkynyl Palmitic Acid (Alk-C16) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Alkynyl Palmitic Acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Alk-C16. CAS No. 99208-90-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W040304. | |
| Allantoin | Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth. Uses: Scientific research. Group: Natural products. Alternative Names: 5-Ureidohydantoin. CAS No. 97-59-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0543. | |
| Allantoin (Standard) | Allantoin (Standard) is the analytical standard of Allantoin. This product is intended for research and analytical applications. Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth. Uses: Scientific research. Group: Natural products. CAS No. 97-59-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0543R. | |
| Allethrin | Allethrin, a pyrethroid insecticide is a major mosquito repellent agent. Allethrin induces oxidative stress, apoptosis and calcium release in rat testicular carcinoma cells (LC540). Allethrin induces BCL-2, caspase-3 activation and release of intracellular calcium [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 584-79-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1559. | |
| Allicin | Allicin (diallyl thiosulfinate) is isolated from garlic including Diallyl monosulfide, Diallyl disulfide, Diallyl trisulfide, Diallyl tetrasulfide, and Methyl allyl disulphide etc. They accounts for 98% of the extract. Allicin (diallyl thiosulfinate) has highly potent antimicrobial activity, and inhibits growth of a variety of microorganisms, among them antibiotic-resistant strains [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Diallyl thiosulfinate. CAS No. 539-86-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0315. | |
| Alliin | Alliin, an orally active sulfoxide compound that can be isolated from garlic, exhibits hypoglycemic, antioxidant, anti-inflammatory and antitumor activities [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 556-27-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0661. | |
| (±)-Alliin | (±)-Alliin is the main active component of garlic. (±)-Alliin is a putative inhibitor of the main protease of SARS-CoV-2 (M pro ) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-L-Alliin. CAS No. 17795-26-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126085. | |
| Allitinib | Allitinib (AST-1306) is an orally active and irreversible EGFR and ErbB2 inhibitor with IC 50 s of 0.5 and 3 nM, respectively. Allitinib also inhibits ErbB4 with an IC 50 of 0.8 nM. Allitinib is an anilino-quinazoline compound and has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AST-1306; ALS 1306. CAS No. 897383-62-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15375. | |
| Allitinib tosylate | Allitinib tosylate (AST-1306 (TsOH)) is an orally active and irreversible EGFR and ErbB2 inhibitor with IC 50 s of 0.5 and 3 nM, respectively. Allitinib tosylate also inhibits ErbB4 with an IC 50 of 0.8 nM. Allitinib tosylate is an anilino-quinazoline compound and has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AST-1306 (TsOH). CAS No. 1050500-29-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13427. | |
| ALLM | ALLM (Calpain inhibitor II) is a potent inhibitor of calpain and cathepsin proteases. ALLM inhibits neuronal cell death and improves chronic neurological function after spinal cord injury (SCI) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Calpain inhibitor II. CAS No. 110115-07-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-118355. | |
| Allo-aca | Allo-aca, a leptin peptidomimetic, is a potent, specific leptin receptor antagonist peptide. Allo-aca blocks leptin signaling and action in numerous in vitro and in vivo models[1][2]. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3212. | |
| Allocholic acid | Allocholic acid is a typically fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis, besides it is also a conjugate acid of allocholate and an isomer of cholic acid. Allocholic acid is a potent and specific stimulant of the adult olfactory system, it has a role as a marine metabolite, a rat metabolite and a human metabolite [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 2464-18-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-125934. | |
| Allocryptopine | Allocryptopine, a derivative of tetrahydropalmatine, is extracted from Macleaya cordata (Thunb.) Pers. Papaveraceae. Allocryptopine has antiarrhythmic effects and potently blocks human ether-a-go-go related gene (hERG) current [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 485-91-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N1933. | |
| Allopurinol | Allopurinol is a potent and orally active xanthine oxidase inhibitor with an IC 50 value of 0.2-50 μM. Allopurinol can be used in the research of hyperuricemia and gout. Allopurinol decreases the expression of HIF-1α and HIF-2α protein. Allopurinol shows anti-depressant and anti-nociception activity. Anti-leishmanial effect [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 315-30-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B0219. | |
| Allopurinol riboside | Allopurinol riboside, a metabolite of allopurinol, shows potent activities against parasites. Uses: Scientific research. Group: Natural products. CAS No. 16220-07-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-101397. | |
| Allopurinol sodium | Allopurinol sodium is a potent and orally active xanthine oxidase inhibitor with an IC 50 value of 0.2-50 μM. Allopurinol sodium can be used in the research of hyperuricemia and gout. Allopurinol sodium decreases the expression of HIF-1α and HIF-2α protein. Allopurinol sodium shows anti-depressant and anti-nociception activity. Anti-leishmanial effect [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 17795-21-0. Pack Sizes: 10 mg; 25 mg. Product ID: HY-B0219A. | |
| Allopurinol (Standard) | Allopurinol (Standard) is the analytical standard of Allopurinol. This product is intended for research and analytical applications. Allopurinol is a potent and orally active xanthine oxidase inhibitor with an IC50 value of 0.2-50 μM. Allopurinol can be used in the research of hyperuricemia and gout. Allopurinol decreases the expression of HIF-1α and HIF-2α protein. Allopurinol shows anti-depressant and anti-nociception activity. Anti-leishmanial effect [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 315-30-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B0219R. | |
| Allotetrahydrocortisol | Allotetrahydrocortisol (5a-Tetrahydrocortisol) is a metabolite of Cortisol. Cortisol is the main glucocorticoid in human. It is produced in adrenal cortex and plays a crucial role in many physiological processes [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 5a-Tetrahydrocortisol. CAS No. 302-91-0. Pack Sizes: 5 mg. Product ID: HY-113215. | |
| Alloxan hydrate | Alloxan hydrate is a diabetogenic agent to induce diabetes. Alloxan hydrate is a proteasome inhibitor. Alloxan causes diabetes in experimental animals through its ability to destroy the insulin-secreting B-cells of the pancreas [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2244-11-3. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-W017227. | |
| all-trans-4-Oxoretinoic acid | all-trans-4-Oxoretinoic acid, an active metabolite of vitamin A, induces gene transcription via binding to nuclear retinoic acid receptors (RARs). Uses: Scientific research. Group: Natural products. Alternative Names: all-trans 4-Keto Retinoic Acid. CAS No. 38030-57-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107494A. | |
| All-trans-retinal | All-trans-retinal is an vitamin A metabolite in the retina, and is produced following photo-isomerization of the visual chromophore 11-cis-Retinal. All-trans-retinal is cleared from photoreceptors by ATP-binding cassette transporter (ABCA4) and all-trans-retinol dehydrogenase (RDH). All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis [1]. Uses: Scientific research. Group: Natural products. CAS No. 116-31-4. Pack Sizes: 100 mg. Product ID: HY-W004500. | |
| Allura Red AC | Allura Red AC is a food colorant, appearing as a deep red water-soluble powder or granules, used in various applications such as beverages, syrups, candies, and cereals. Allura Red AC can statically quench the intrinsic fluorescence of HSA. Additionally, Allura Red AC is a 5-hydroxytryptamine ( 5-HT ) pathway-associated pro-inflammatory agent, capable of exacerbating experimental colitis. Allura Red AC holds potential for research in inflammatory bowel disease (IBD), intestinal barrier function, and food additive safety [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: FD&C RED NO. 40; CI 16035. CAS No. 25956-17-6. Pack Sizes: 50 mg; 100 mg. Product ID: HY-123630. | |
| Allylestrenol | Allylestrenol, a synthetic sexualsteroid, is used worldwide in case of endangered pregnancies. Uses: Scientific research. Group: Signaling pathways. CAS No. 432-60-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17375. | |
| Allyl heptanoate | Allyl heptanoate is an ester that is formed by the esterification of medium-chain fatty acids, heptanoic acid and allyl alcohol. The compound has a fruity smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Prop-2-en-1-yl heptanoate. CAS No. 142-19-8. Pack Sizes: 5 g; 25 g. Product ID: HY-W016976. | |
| Allylic-SAM | Allylic-SAM is an S-adenosyl methionine (SAM) analog for the enrichment and detection of methyltransferase target sites in RNA. Uses: Scientific research. Group: Signaling pathways. CAS No. 875155-64-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148904. | |
| Allyl methyl sulfide | Allyl methyl sulfide is a bioactive organosulfur compound found in garlic. Allyl methyl sulfide exhibits antibacterial, antioxidant and anticancer properties [1]. Uses: Scientific research. Group: Natural products. CAS No. 10152-76-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-128447. | |
| Allylthiourea | Allylthiourea can selectively inhibit the oxidation of ammonia. Allylthiourea is commonly used to inhibit nitrification by targeting ammonia monooxygenase and chelating copper in the active site to suppress its activity. Allylthiourea also exhibits anticancer activity, showing cytotoxicity against the MCF-7 cell line with an IC 50 of 5.22 mM. Allylthiourea can be utilized in research related to micropollutant biodegradability and cancer studies [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Thiosinamine; N-Allylthiourea. CAS No. 109-57-9. Pack Sizes: 10 mM * 1 mL; 25 g; 50 g. Product ID: HY-B0543. | |
| Allyltrimethylsilane | Allyltrimethylsilane (Trimethyl-prop-2-enylsilane) is a biological molecule. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Trimethyl-prop-2-enylsilane. CAS No. 762-72-1. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-W019828. | |
| Almitrine mesylate | Almitrine mesylate, a peripheral chemoreceptor agonist, inhibits selectively the Ca 2+ -dependent K + channel. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Almitrine bismesylate; Almitrine bismethanesulfonate; Almitrine dimesylate. CAS No. 29608-49-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107319. | |
| Almonertinib | Almonertinib (HS-10296) is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 ( IC 50 : 0.37, 0.29 and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). Almonertinib is used for the research of the non-small cell lung cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HS-10296. CAS No. 1899921-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112823. | |
| Almonertinib hydrochloride | Almonertinib (HS-10296) hydrochloride is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib hydrochloride shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 ( IC 50 : 0.37, 0.29 and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). Almonertinib hydrochloride is used for the research of the non-small cell lung cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HS-10296 hydrochloride. CAS No. 2134096-03-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112823B. | |
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