MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| AM3102 | AM3102 is an oleoylethanolamide (OEA) analog. AM3102 is an endogenous high-affinity PPAR-alpha agonist. AM3102 resists enzymatic hydrolysis, activates PPAR-alpha with high potency in vitro, and persistently reduces feeding when administered in vivo either parenterally or orally [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 213182-22-0. Pack Sizes: 5 mg. Product ID: HY-129683. |  |
| AM 374 | AM 374 is an fatty acid amide hydrolase (FAAH) inhibitor. AM 374 inhibits amidase activity with an IC 50 value of 13 nM. AM 374 can be used for the research of neurological disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 86855-26-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125967. | |
| AM580 | AM580 is a selective RAR? agonist with IC50 and EC50 of 8 nM and 0.36 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CD336; NSC608001; Ro 40-6055. CAS No. 102121-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10475. | |
| AM6545 | AM6545 is a highly selective, brain-free (peripherally active) CB1 receptor antagonist ( K i =1.7 nM). AM6545 inhibits endocannabinoid signaling by competitively antagonizing CB1 receptors, inhibiting CB1-mediated appetite stimulation and inflammatory responses without affecting cAMP levels. AM6545 significantly reduces food intake and body weight in mice, while improving metabolic syndrome-related renal impairment (such as proteinuria, fibrosis) and insulin resistance. AM6545 can be used in the study of obesity and its complications [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1245626-05-4. Pack Sizes: 1 mg. Product ID: HY-110206. | |
| AM966 | AM966 is a high affinity, selective, oral LPA1-antagonist, inhibits LPA-stimulated intracellular calcium release (IC50=17 nM). Uses: Scientific research. Group: Signaling pathways. CAS No. 1228690-19-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15277. | |
| AMA-37 | AMA-37, an Arylmorpholine analog, is ATP-competitive DNA-PK inhibitor, with IC 50 values of 0.27 μM (DNA-PK), 32 μM (p110α), 3.7 μM (p110β), and 22 μM (p110γ), respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 404009-46-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100706. | |
| Amantadine | Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2 , and also inhibits Coronavirus ion channels. Amantadine also has anti- orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-Adamantanamine; 1-Aminoadamantane. CAS No. 768-94-5. Pack Sizes: 500 mg. Product ID: HY-B0402. | |
| Amantadine hydrochloride | Amantadine (1-Adamantanamine) hydrochloride is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine hydrochloride inhibits several ion channels such as NMDA and M2 , and also inhibits Coronavirus ion channels. Amantadine hydrochloride also has anti- orthopoxvirus and anticancer activity. Amantadine hydrochloride can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-Adamantanamine hydrochloride; 1-Adamantylamine hydrochloride; 1-Aminoadamantane hydrochloride. CAS No. 665-66-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g; 50 g. Product ID: HY-B0402A. | |
| Amaranth | Amaranth is an organic azo dye. Amaranth inhibits cellular immune response. Amaranth can be used as a food additive [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Red 27; Azorubin S; FD & C Red Dye No. 2. CAS No. 915-67-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-D0307A. | |
| Amarogentin | Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis , arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 21018-84-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2447. | |
| AMAS | AMAS is a nonclaevable heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules. Uses: Scientific research. Group: Signaling pathways. CAS No. 55750-61-3. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-128925. | |
| Amastatin hydrochloride | Amastatin hydrochloride is a slow, tight binding, competitive aminopeptidase (AP) inhibitor with K i values of 0.26 nM, 30 nM, 52 nM for Aeromonas aminopeptidase, cytosolic leucine aminopeptidase, microsomal aminopeptidase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 100938-10-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-115194. | |
| Amatuximab | Amatuximab (MORab-009) is a chimeric, humanized IgG1/k MAb that targets the cell surface mesothelin (MSLN). Mesothelin is a glycosylphosphatidyl inositol (GPI)-anchored membrane glycoprotein, which is present in a restricted set of normal adult tissues such as the mesothelium [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MORab-009. CAS No. 931402-35-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99006. | |
| Ambazone | Ambazone is an orally active membrane active antitumor agent. Ambazone also shows antibacterial and weak antiviral activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 539-21-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-122356A. | |
| Ambenonium chloride | Ambenonium (WIN 8077) chloride is an orally active and reversible inhibitor of Acetyicholinesterase ( AChE ) with high affinity. Ambenonium chloride inhibits human AChE with an IC 50 value of 0.7 nM (hAChE) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WIN 8077 chloride. CAS No. 115-79-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-100919. | |
| Ambrisentan | Ambrisentan is a selective ET type A receptor ( ETAR ) antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BSF 208075; LU 208075. CAS No. 177036-94-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13209. | |
| Ambroxide | Ambroxide is a naturally occurring terpenoid. Ambroxide is one of the key constituents of ambergris. Uses: Scientific research. Group: Natural products. CAS No. 6790-58-5. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N1384. | |
| Ambroxol | Ambroxol (NA-872), an active metabolite of the proagent Bromhexine, has potent expectorant effects. Ambroxol is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol induces lung autophagy and has the potential for Parkinson disease and neuronopathic Gaucher disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NA-872. CAS No. 18683-91-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1039. | |
| Ambroxol hydrochloride | Ambroxol hydrochloride (NA-872 hydrochloride), an active metabolite of the proagent Bromhexine, has potent expectorant effects. Ambroxol hydrochloride is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol hydrochloride induces lung autophagy and has the potential for Parkinson disease and neuronopathic Gaucher disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NA-872 hydrochloride. CAS No. 23828-92-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1039A. | |
| Ambuic acid | Ambuic acid exhibits antimicrobial activity against Staphylococcus aureus , with IC 50 of 43.9 μM for strain ATCC 6538. Ambuic acid is an inhbitor for the biosynthesis of cyclic peptide quorum sensing molecules (quormones) in gram-positive bacteria. Ambuic acid exhibits anti-inflammatory activity through ERK/JNK/MAPK signaling pathway [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Ambuic acid. CAS No. 340774-69-8. Pack Sizes: 500 μg. Product ID: HY-126858. | |
| Amcenestrant | SAR439859 (compound 43d) is an orally active, non-steroidal, and selective estrogen receptor degrader (SERD). SAR439859 is an effective ER antagonist with ER degradation activity, an EC 50 of 0.2 nM. SAR439859 can show potent anti-tumor effects and limited cross-resistance in ER + breast cancer. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAR439859. CAS No. 2114339-57-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133017. | |
| Amcinonide | Amcinonide is a NO inhibitor that inhibits NO release from activated microglia with IC 50 of 3.38 nM. Amcinonide has glucocorticoid receptor affinity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CL-34699. CAS No. 51022-69-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1197. | |
| AMD 3465 hexahydrobromide | AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide) is a potent antagonist of CXCR4 , inhibits binding of 12G5 mAb and CXCL12 AF647 to CXCR4 , with IC 50 s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains ( IC 50 : 1-10 nM), but has no effect on CCR5-using (R5) viruses. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GENZ-644494 hexahydrobromide. CAS No. 185991-07-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15971. | |
| Amelenodor | NX-13 is a first-in-class, orally active and gut-restricted agent that selectively targets and activates the NLRX1 pathway to induce immunometabolic changes. NX-13 results in lower inflammation and responses in inflammatory bowel disease. NX-13 can be used for the research of crohn's disease and ulcerative colitis[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NX-13. CAS No. 2389235-01-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141521. | |
| Amenamevir | Amenamevir is a helicase-primase inhibitor which has potent antiviral activity against HSVs with an EC 50 of 14 ng/mL. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASP2151. CAS No. 841301-32-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14809. | |
| Amentoflavone | Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Didemethyl-ginkgetin. CAS No. 1617-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0662. | |
| Ametryn | Ametryn, a member of the Triazine chemical family, is a herbicide which inhibits photosynthesis and other enzymatic processes. Ametryn is effective against annual broadleaf weeds and grasses [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 834-12-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-B0866. | |
| Amezinium methylsulfate | Amezinium metilsulfate has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition ofnoradrenaline and tyramine uptake. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Amezinium metilsulfate; Lu-1631. CAS No. 30578-37-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-A0275. | |
| Amfenac Sodium Hydrate | Amfenac Sodium Hydrate is a COX-2 inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 61618-27-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17479A. | |
| AMG131 | AMG131 (INT131) is a potent non-thiazolidinedione (TZD) selective peroxisome proliferator-activated receptor ? modulator (SPPARM). AMG131 binds to PPAR? within the same binding pocket as the TZDs, but occupies a unique space in the pocket and contacts the receptor at distinct points from the TZDs. AMG131 is promising for research of type-2 diabetes mellitus[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INT131. CAS No. 315224-26-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117103. | |
| AMG-193 | AMG 193 is an orally active MTA-cooperative PRMT5 inhibitor with antitumor activity. AMG 193, when complexed with MTA, preferentially inhibits the growth of MTAP-deficient tumor cells by inhibiting PRMT5 ( IC 50 =0.107 μM), thereby protecting normal cells with wild-type MTAP [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2790567-82-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153390. | |
| AMG319 | AMG319 is a potent and selective PI3Kδ kinase inhibitor with IC 50 of 18 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1608125-21-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12948. | |
| AMG 333 | AMG 333 is an orally active and highly selective TRPM8 antagonist with an IC50 of 13 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1416799-28-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112703. | |
| AMG-337 | AMG-337 is a potent, orally active, selective MET kinase inhibitor with IC 50 values of 1, 1, 4.7, 5, 21.5, 1077 and >4000 nM of WT MET, H1094R MET, M1250T MET, HGF-stimulated pMET (PC3 cells) MET, V1092I MET, Y1230H MET, and D1228H MET, respectively. AMG 337 inhibits the phosphorylation of MET and downstream effectors in MET-amplified cancer cell lines, resulting in an inhibition of MET-dependent cell proliferation and induction of apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1173699-31-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-18696. | |
| AMG410 | AMG410 is a non-covalent and selective pan-KRAS inhibitor with IC50 values of 1-4 nM for KRAS G12D, KRAS G12V, and KRAS G13D. AMG410 shows greater than 100-fold selectivity against both HRAS and NRAS. AMG410 is a dual GTP(on)- and GDP(off)-state inhibitor (Kd(GDP-state) of 1 nM; Kd(GTP-state) of 22 nM). AMG410 blocks KRAS signaling in a cycling state-independent manner and also blocks proliferation in wildtype KRAS-amplified tumor cells. AMG410 can be used for the study of colorectal, pancreatic, and lung cancers[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3040175-17-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173632. | |
| AMG-47a | AMG-47a is an orally active, ATP-competitive Lck inhibitor (IC50=0.2 nM). AMG-47a inhibits VEGF2, p38?, p38?, Jak3, MLR, and IL-2 with IC50 of 1 nM, 3 nM, 72 nM, 30 nM, and 21 nM, respectively. AMG-47a reduces T cell activation and the production of cytokines such as TGF-?, exerting anti-inflammatory and anti-fibrotic activities. AMG-47a can be used in the research of autoimmune diseases, pulmonary fibrosis, and KRAS mutation-associated cancers[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 882663-88-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-18303. | |
| AMG 487 | AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 473719-41-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15319. | |
| AMG 511 | AMG 511 is a potent and orally available pan inhibitor of class I PI3Ks, with Kis of 4 nM, 6 nM, 2 nM and 1 nM for PI3K?, ?, ? and ?, respectively. AMG 511 significantly suppresses PI3K signaling that is indicated by p-Akt (Ser473) decrease. AMG 511 exhibits anti-tumor activity in mouse glioblastoma xenograft model[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1253573-53-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-13440. | |
| AMG 517 | AMG 517 is a potent and selective vanilloid receptor-1 ( TRPV1 ) antagonist with an IC 50 of 0.5 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 659730-32-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10634. | |
| AMG-548 | AMG-548, an orally active and selective p38α inhibitor ( K i=0.5 nM), shows slightly selective over p38β ( K i=36 nM) and >1000 fold selective against p38γ and p38&delta. AMG 548 is also extremely potent in the inhibition of whole blood LPS stimulated TNFα ( IC 50 =3 nM) [1]. AMG-548 inhibits Wnt signaling by directly inhibiting Casein kinase 1 isoforms δ and ε [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 864249-60-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108642. | |
| AMG-548 dihydrochloride | AMG-548 dihydrochloride, an orally active and selective p38α inhibitor ( K i=0.5 nM), shows slightly selective over p38β ( K i=36 nM) and >1000 fold selective against p38γ and p38&delta. AMG-548 dihydrochloride is also extremely potent in the inhibition of whole blood LPS stimulated TNFα ( IC 50 =3 nM) [1]. AMG-548 dihydrochloride inhibits Wnt signaling by directly inhibiting Casein kinase 1 isoforms δ and ε [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2518299-32-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108642B. | |
| AMG 900 | AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor with IC 50 of 5 nM, 4 nM and 1 nM for Aurora A , B and C , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 945595-80-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13253. | |
| AMG9810 | AMG9810 is a selective and competitive vanilloid receptor 1 ( TRPV1 ) antagonist with IC 50 values of 24.5 and 85.6 nM for human and rat TRPV1, repectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 545395-94-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101736. | |
| AMG PERK 44 | AMG PERK 44 is an orally active and highly selective PERK inhibitor with an IC50 of 6 nM. AMG PERK 44 has 1000-fold and 160-fold selectivity over GCN2 (IC50=7300 nM) and B-Raf (IC50 >1000 nM), respectively. AMG PERK 44 induces autophagy[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1883548-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12661A. | |
| Amibegron hydrochloride | Amibegron hydrochloride is a selective β3-adrenoceptor agonist, with an EC 50 of 3.5 nM for β-adrenoceptor in rat colon; Amibegron hydrochloride has anxiolytic and antidepressant activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR 58611A. CAS No. 121524-09-2. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-103207. | |
| Amicarbazone | Amicarbazone (BAY-MKH3586; BAY314666) becomes an effective inhibitor of photosynthetic electron transport by binding to the Qb site of photosystem II (PSII); it is a herbicide with broad-spectrum weed control. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY314666; BAY-MKH 3586. CAS No. 129909-90-6. Pack Sizes: 100 mg. Product ID: HY-17513. | |
| Amidase | Amidases, a member of nitrilase superfamily, catalyzes the hydrolysis of an amide, leading to the formation of carboxylic acid and ammonia. Amidases contain a conserved stretch of approximately 130 amino acids known as the AS sequence, and play a role in important metabolic processes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9012-56-0. Pack Sizes: 250 U; 1 KU. Product ID: HY-P2736. | |
| Amidosulfuron | Amidosulfuron is a herbicide. Amidosulfuron targets acetohydroxyacid synthase (AHAS) , is highly effective against dicot broad-leaf weeds [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120923-37-7. Pack Sizes: 10 mg; 50 mg. Product ID: HY-B1912. | |
| Amifampridine | Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (K v ) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3,4-Diaminopyridine. CAS No. 54-96-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-14946. | |
| Amifloxacin | Amifloxacin (Win49375) is a synthetic antibacterial agent of the quinolone class. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Win49375. CAS No. 86393-37-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-U00221. | |
| Amifostine | Amifostine (WR2721) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer. Amifostine protects cells from damage by scavenging oxygen-derived free radicals. Amifostine reduces renal toxicity and has antiangiogenic action [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WR2721. CAS No. 20537-88-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0639. | |
| Amifostine trihydrate | Amifostine trihydrate (WR2721 trihydrate) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine trihydrate selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine trihydrate is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer. Amifostine trihydrate protects cells from damage by scavenging oxygen-derived free radicals. Amifostine trihydrate reduces renal toxicity and has antiangiogenic action [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WR2721 trihydrate. CAS No. 112901-68-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0639A. | |
| Amikacin | Amikacin (BAY 41-6551) is a semisynthetic kanamycin analog that is active against most Gram-negative bacteria, including gentamicin- and tobramycin-resistant strains. Significant inhibitory effect. Amikacin is ototoxic and nephrotoxic. Amikacin can be used in bacteriostatic, anti-cancer and analgesic studies [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 41-6551. CAS No. 37517-28-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0509A. | |
| Amikacin disulfate | Amikacin disulfate (BAY 41-6551 dissulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin disulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin disulfate is very active against most Gram-negative bacteria including gentamicin - and tobramycin-resistant strains. Amikacin disulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 41-6551 disulfate. CAS No. 39831-55-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0509B. | |
| Amikacin hydrate | Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin hydrate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin hydrate is very active against most Gram-negative bacteria including gentamicin - and tobramycin-resistant strains. Amikacin hydrate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 41-6551 hydrate. CAS No. 1257517-67-1. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-B0509. | |
| Amikacin sulfate | Amikacin sulfate (BAY 41-6551 sulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin sulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin sulfate is very active against most Gram-negative bacteria including gentamicin - and tobramycin-resistant strains. Amikacin sulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 41-6551 sulfate. CAS No. 149022-22-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-107813. | |
| Amiloride | Amiloride (MK-870) is an inhibitor of both epithelial sodium channel ( ENaC [1] ) and urokinase-type plasminogen activator receptor ( uTPA [2] ). Amiloride is a blocker of polycystin-2 (PC2; TRPP2 [3] ) channel. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-870. CAS No. 2609-46-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0285. | |
| Amiloride hydrochloride | Amiloride hydrochloride (MK-870 hydrochloride) is an inhibitor of both epithelial sodium channel ( ENaC [1] ) and urokinase-type plasminogen activator receptor ( uTPA [2] ). Amiloride hydrochloride is a blocker of polycystin-2 (PC2; TRPP2 [3] ) channel. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-870 hydrochloride. CAS No. 2016-88-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0285A. | |
| Amiloride hydrochloride dihydrate | Amiloride hydrochloride dihydrate (MK-870 hydrochloride dihydrate) is an inhibitor of both epithelial sodium channel ( ENaC [1] ) and urokinase-type plasminogen activator receptor ( uTPA [2] ). Amiloride hydrochloride dihydrate is a blocker of polycystin-2 (PC2; TRPP2 [3] ) channel. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-870 hydrochloride dihydrate. CAS No. 17440-83-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0285B. | |
| Amiloride (hydrochloride) (Standard) | Amiloride (hydrochloride) (Standard) is the analytical standard of Amiloride (hydrochloride). This product is intended for research and analytical applications. Amiloride hydrochloride (MK-870 hydrochloride) is an inhibitor of both epithelial sodium channel ( ENaC [1] ) and urokinase-type plasminogen activator receptor ( uTPA [2] ). Amiloride hydrochloride is a blocker of polycystin-2 (PC2; TRPP2 [3] ) channel. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-870 hydrochloride (Standard). CAS No. 2016-88-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-B0285AR. | |
| Amine-PEG3-Biotin | Amine-PEG3-Biotin is a signal amplification label containing a biotin group and a terminal primary amine group [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 359860-27-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111377. | |
| Amine-PEG3-Desthiobiotin | Amine-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2237234-71-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-134721. | |
| Amino-3,5-dibromopyrazine | Amino-3,5-dibromopyrazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 3,5-Dibromo-2-pyrazinamine; 3,5-Dibromopyrazin-2-ylamine. CAS No. 24241-18-7. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-79805. | |
| Aminoacetone hydrochloride | Aminoacetone hydrochloride is the simplest monopeptide. Aminoacetone hydrochloride is an intermediate in the metabolism of threonine and glycine. Aminoacetone hydrochloride is an endogenous substrate for semicarbazide-sensitive amine oxidase ( SSAO ), and can be used for determination of SSAO activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7737-17-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W004850. | |
| Aminoacyl tRNA synthetase-IN-1 | Aminoacyl tRNA synthetase-IN-1 is a bacterial aminoacyl tRNA synthetase ( aaRS ) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 219931-45-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108939. | |
| Aminoadipic acid | Aminoadipic acid is an orally active lysine oxide derivative. Aminoadipic acid induces ROS generation, increases free Ca 2+ , decreases SOD , and activates TXNIP/NLRP3 pathway. Aminoadipic acid has pro-inflammatory effects. Aminoadipic acid can be used in atherosclerosis research [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 542-32-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-113328. | |
| Aminoglutethimide | Aminoglutethimide is an aromatase inhibitor with IC50 of 10 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DL-Aminoglutethimide. CAS No. 125-84-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0237. | |
| Aminoguanidine hydrochloride | Aminoguanidine hydrochloride (Pimagedine hydrochloride) is an inhibitor of diamine oxidase and nitric oxide synthase. Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin (HY-15142). Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in diabetic nephropathy research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pimagedine hydrochloride; GER-11; Aminoguanidinium chloride. CAS No. 1937-19-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1041. | |
| Aminohexylgeldanamycin | Aminohexylgeldanamycin (AHGDM), a Geldanamycin derivative, is a potent HSP90 inhibitor. Aminohexylgeldanamycin shows antiangiogenic and antitumor activities [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AHGDM. CAS No. 485395-71-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-133571. | |
| Aminohippurate sodium | Aminohippurate sodium is a diagnostic agent useful in medical tests involving the kidney used in the measurement of renal plasma flow. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sodium p-aminohippurate; p-Aminohippuric acid sodium salt. CAS No. 94-16-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-A0080. | |
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