MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| AGK2 | AGK2 is a selective SIRT2 inhibitor with an IC50 of 3.5 ?M. AGK2 inhibits SIRT1 and SIRT3 with IC50s of 30 and 91 ?M, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 304896-28-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100578. |  |
| Agmatine sulfate | Agmatine sulfate exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor. Uses: Scientific research. Group: Natural products. CAS No. 2482-00-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-101238. | |
| AGN 193109 | AGN 193109 is a retinoid analog, and acts as a specific and highly effective antagonist of retinoic acid receptors (RARs) , with K d s of 2 nM, 2 nM, and 3 nM for RARα , RARβ , and RARγ , respectively. AGN 193109 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. AGN 193109 is the antidote for retinoic acidosis, that ameliorates the skin and mucosal toxicity. Uses: Scientific research. Group: Signaling pathways. CAS No. 171746-21-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00449. | |
| AGN194204 | AGN194204 (IRX4204) is an orally active and selective RXR agonist with Kd values 0.4 nM, 3.6 nM and 3.8 nM and EC50s of 0.2 nM, 0.8 nM and 0.08 nM for RXR?, RXR? and RXR?, respectively. AGN194204 is inactive against RAR. AGN194204 has anti-inflammatory and anticarcinogenic actions[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IRX4204; NRX194204; VTP 194204. CAS No. 220619-73-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-13717. | |
| AGN 194310 | AGN 194310 (VTP-194310) is a high affinity, potent and selective retinioic acid receptors (RARs) pan-antagonist with Kd values of 3 nM, 2 nM, 5 nM for RAR?, RAR?, RAR?, respectively[1][2]. AGN 194310 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VTP-194310. CAS No. 229961-45-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-16681. | |
| Agnuside | Agnuside is used in the study of asthma, inflammation, and angiogenic diseases. Agnuside is an orally active compound that can be extracted from Vitex negundo [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Agnoside. CAS No. 11027-63-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2518. | |
| Agomelatine | Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with K i s of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively [1]. Agomelatine is a selective 5-HT2C receptor antagonist with pK i s of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: S-20098. CAS No. 138112-76-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17038. | |
| Agomelatine hydrochloride | Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with K i s of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively [1]. Agomelatine hydrochloride is a selective 5-HT2C receptor antagonist with pK i s of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: S-20098 hydrochloride. CAS No. 1176316-99-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17038A. | |
| AGPS-IN-1 | AGPS-IN-1 (Compound 2i) is an effective AGPS binder. AGPS-IN-1 reduces ether lipids levels and cell migration rate. AGPS-IN-1 inhibits epithelial-mesenchymal transition (EMT) in prostate PC-3 and breast MDA-MB-231 cancer cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2316782-88-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-153910. | |
| Agrimol B | Agrimol B, a polyphenol, is an orally active and potent SIRT1 activator. Agrimol B shows anti-adipogenic and anticancer activity. Agrimol B shows antibacterial activity against plant pathogens. Agrimol B dramatically inhibits 3T3-L1 adipocyte differentiation by reducing PPAR?, C/EBP?, FAS, UCP-1, and apoE expression. The action of Agrimol B on the cancer cells is likely derived from its effect on c-MYC, SKP2 and p27[1][2][3]. Uses: Scientific research. Group: Natural products. CAS No. 55576-66-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0704. | |
| AGX51 | AGX51 is the first-in-class pan-Id (inhibitors of DNA-binding/differentiation proteins) antagonist and degrader. AGX51 inhibits Id1-E47 interaction, leading to ubiquitin-mediated degradation of Ids, cell growth arrest, and viability reduction. AGX51 can inhibit TNBC and has an IC50 of about 25 nM. AGX51 can be used in cancer research. Uses: Scientific research. Group: Signaling pathways. CAS No. 330834-54-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129241. | |
| AH1 | AH1 is an immunodominant antigen derived from the gp70 product of an endogenous MuLV. AH1 behaves as the CTL-immunodominant epitope of CT26 colon carcinoma [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 181272-91-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4193. | |
| AH-7614 | AH-7614 is a potent and selective FFA4 (GPR120) antagonist, with pIC 50 s of 7.1, 8.1, and 8.1 for human, mouse, and rat FFA4, respectively. AH-7614 has selectivity for FFA4 over FFA1 (pIC 50 <4.6). AH-7614 is able to block effects of both the polyunsaturated ω-6 fatty acid linoleic acid and the synthetic FFA4 agonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6326-6-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19996. | |
| AHR-1911 | AHR-1911 (10-Undecen-1-yl-Thiopseudourea Iodide;Isothiuronium) is a thiourea-based anti-inflammatory and anti-tumor agent that has an improving effect on burned skin. AHR-1911 produces histamine-like effects when injected intradermally and may reduce arterial pressure in anesthetized dogs. AHR-1911 inhibits tumor growth and reduces microsomal and C-polysome protein synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 10-Undecen-1-yl-thiopseudourea iodide. CAS No. 22584-04-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107063. | |
| AI-10-104 | AI-10-104 is an inhibitor for runt-related transcription factor (RUNX), which enhances the cytotoxicity in myeloma cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1881276-00-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122657. | |
| AI-10-49 | AI-10-49 is an inhibitor of leukemic oncoprotein CBF?-SMHHC. AI-10-49 inhibits the binding of CBF?-SMMHCto the RUNX1 Runt domain with IC50 value of 0.26 ?M. AI-10-49 can be used for the research of leukemia[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1256094-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16786. | |
| AICAR | AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy , YAP and mitophagy inhibitor [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Acadesine; AICA Riboside. CAS No. 2627-69-2. Pack Sizes: 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13417. | |
| AICAR phosphate | AICAR phosphate (Acadesine phosphate) is an adenosine analog and a AMPK activator. AICAR phosphate regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR phosphate is also an autophagy , YAP and mitophagy inhibitor [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Acadesine phosphate; AICA Riboside phosphate. CAS No. 681006-28-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13417A. | |
| Ailanthone | Ailanthone (Δ13-Dehydrochaparrinone) is a potent inhibitor of both full-length androgen receptor (AR) ( IC 50 =69?nM) and constitutively active truncated AR splice variants (AR 1-651 IC 50 =309?nM). Uses: Scientific research. Group: Natural products. Alternative Names: Δ13-Dehydrochaparrinone. CAS No. 981-15-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1943. | |
| AJ2-30 | AJ2-30 is a SLCl5A4 inhibitor. AJ2-30 inhibits endolysosomal TLR7-9-mediated mTOR activation. AJ2-30 blocks endogenous NOD signaling. AJ2-30 can be used in inflammation studies[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2700322-79-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155864. | |
| Ajmalicine | Ajmalicine (Raubasine) is a potent adrenolytic agent which preferentially blocks α 1 -adrenoceptor. Ajmalicine is an reversible but non-competitive nicotine receptor full inhibitor, with an IC 50 of 72.3 μM. Ajmalicine also can be used as anti-hypertensive, and serpentine, with sedative activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Raubasine. CAS No. 483-04-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N1919. | |
| Ajmaline | Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC 50 of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cardiorythmine; (+)-Ajmaline. CAS No. 4360-12-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1167. | |
| Ajoene | Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 92285-01-3. Pack Sizes: 1 mg (21.33 mM * 200 μL in Ethyl acetate). Product ID: HY-106784. | |
| AK-1 | AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor, with an IC 50 of 12.5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 330461-64-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101465. | |
| AK-1690 | AK-1690 is a potent and selective STAT6 PROTAC degrader. AK-1690 reduces the levels of STAT6 protein in cells (DC50=1 nM) and depletes STAT6 protein in mouse tissues. AK-1690 can be used for the research of cancer. (Pink: ligand for target protein STAT6 (HY-169182); Black: linker (HY-W459522); Blue: ligand for E3 ligase (HY-131318)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2984505-88-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169179. | |
| AK-2292 | AK-2292 is a potent and selective STAT5 PROTAC degrader, with a DC50 of 0.10 ?M. AK-2292 induces degradation of STAT5A/B proteins in vitro and in vivo. AK-2292 can induce tumor regression in acute myeloid leukemia and chronic myeloid leukemia xenograft mouse models[1][2]. AK-2292 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2984506-77-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148813. | |
| AK-7 | AK-7 is a selective cell- and brain-permeable SIRT2 inhibitor, with an IC 50 of 15.5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 420831-40-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16691. | |
| AK-778-XXMU | AK-778-XXMU is a potent inhibitor of DNA Binding 2 (ID2) antagonist with a KD of 129 nM. AK-778-XXMU can inhibit cell migration and invasion of glioma cell lines, induce apoptosis, and more importantly, slow down the tumor growth[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1227045-76-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144707. | |
| AkaLumine hydrochloride | AkaLumine hydrochloride is a D-luciferin (HY-12591A) analogue with a Km of 2.06 ?M for recombinant firefly luciferase (Fluc) protein. AkaLumine hydrochloride emits near-infrared (NIR) light (?max=677?nm) in reactions with native Fluc. AkaLumine hydrochloride has high tissue-penetration and increases detection sensitivity from deep-tissue targets[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2558205-28-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112641A. | |
| AKBA | AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. Uses: Scientific research. Group: Natural products. Alternative Names: Acetyl-11-keto-β-boswellic acid. CAS No. 67416-61-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0892. | |
| AKBA (Standard) | AKBA (Standard) is the analytical standard of AKBA. This product is intended for research and analytical applications. AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. Uses: Scientific research. Group: Natural products. CAS No. 67416-61-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0892R. | |
| AKR1C1-IN-1 | AKR1C1-IN-1 is a potent and selective inhibitor of human 20?-hydroxysteroid dehydrogenase (AKR1C1), with a Ki value of 4 nM for AKR1C1[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4906-68-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114009. | |
| AKT-IN-23 | AKT-IN-23 is an AKT inhibitor. AKT-IN-23 can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1226801-23-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161704. | |
| AKT inhibitor IV | Akt inhibitor-IV (AKTIV) acts as a PI3K-Akt inhibitor at the E isomer (HY-14971), with potent cytotoxicity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKTIV. CAS No. 681281-88-9. Pack Sizes: 1 mg. Product ID: HY-14971A. | |
| AKT inhibitor VIII | AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKTi-1/2. CAS No. 612847-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10355. | |
| AKT Kinase Inhibitor | AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 842148-40-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-10249A. | |
| AKT Kinase Inhibitor hydrochloride | AKT Kinase Inhibitor hydrochloride is an Akt kinase inhibitor with anti-tumor activity [1]. AKT Kinase Inhibitor (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 3026697-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10249D. | |
| AL-9 | AL-9 is a inhibitor of PI4KIIIα, with the IC 50 of 0.57 μM, that can inhibit HCV replication [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 869218-90-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118525. | |
| [Ala11,D-Leu15]-Orexin B(human) | [Ala11,D-Leu15]-Orexin B(human) is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B(human) shows a 400-fold selectivity for the OX2 ( EC 50 =0.13 nM) over OX1 (52 nM) [1]. Uses: Scientific research. Group: Peptides. CAS No. 532932-99-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1340. | |
| Ala-D-γ-Glu-Lys-D-Ala-D-Ala | Ala-D-γ-Glu-Lys-D-Ala-D-Ala is the pentapeptide tail of the peptidoglycan precursor UDPMurNAc-l-Ala-γ-d-Glu-l-Lys(Gly)(5)-d-Ala-d-Ala [1]. Uses: Scientific research. Group: Peptides. CAS No. 2614-55-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P5919. | |
| Alagebrium chloride | Alagebrium chloride (ALT711) is an advanced glycation end product ( AGE ) inhibitor. Uses: Scientific research. Group: Natural products. Alternative Names: ALT711. CAS No. 341028-37-3. Pack Sizes: 10 mM * 1 mL; 200 mg. Product ID: HY-106024B. | |
| Alamandine | Alamandine, a member of the renin-angiotensin system (RAS), a vasoactive peptide, is an endogenous ligand of the G protein-coupled receptor MrgD. Alamandine targets to protect the kidney and heart through anti-hypertensive actions[1][2]. Uses: Scientific research. Group: Peptides. CAS No. 1176306-10-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3108. | |
| Alamethicin | Alamethicin is a linear 20-amino acid antibiotic , which can induce voltage-gated conductance in model and cell membranes. Alamethicin exhibits antimicrobial activity against Gram-positive bacteria, but not Gram-negative bacteria. Alamethicin can form an amphipathic α-helical structure in biological membranes [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 27061-78-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6708. | |
| Alamifovir | Alamifovir (LY582563; MCC-478), a purine nucleotide analogue proagent, shows potent activity against wild type and lamivudine resistant hepatitis B virus (HBV). Alamifovir has high activity against HBV replication and sustained antiviral effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY582563; MCC-478. CAS No. 193681-12-8. Pack Sizes: 1 mg. Product ID: HY-119691. | |
| Alanine-2,3,3,3-d4 | Alanine-2,3,3,3-d4 is the deuterium labeled Alanine-2,3,3,3[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 53795-92-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W244382. | |
| Alanine aminotransferase, Porcine heart | Alanine aminotransferase, Porcine heart is a pyridoxal enzyme that catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9000-86-6. Pack Sizes: 200 U. Product ID: HY-P2985. | |
| Alanine dehydrogenase, expressed in E. coli | Alanine dehydrogenase, expressed in E. coli is a microbial enzyme that catalyzes a reversible conversion of L-alanine to pyruvate [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9029-6-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2854. | |
| Alantolactone | Alantolactone is a selective STAT3 inhibitor, with potent anticancer activity. Alantolactone induces apoptosis in cancer [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Alantolactone; Alant camphor; Inula camphor. CAS No. 546-43-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0038. | |
| Alarelin Acetate | Alarelin acetate is a synthetic GnRH agonist. Uses: Scientific research. Group: Peptides. Alternative Names: Alarelin. CAS No. 79561-22-1. Pack Sizes: 5 mg; 10 mg; 100 mg. Product ID: HY-17405. | |
| Albendazole | Albendazole (SKF-62979) is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity, is used for the research of gastrointestinal parasites in humans and animals. Albendazole induces apoptosis and autophagy in cancer cells. Albendazole also inhibits tubulin polymerization and HIF-1α , VEGF expression, has antioxidant activity, and inhibits the glycolytic process in cancer cells [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF-62979. CAS No. 54965-21-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0223. | |
| Albendazole (Standard) | Albendazole (Standard) is the analytical standard of Albendazole. This product is intended for research and analytical applications. Albendazole (SKF-62979) is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity, is used for the research of gastrointestinal parasites in humans and animals. Albendazole induces apoptosis and autophagy in cancer cells. Albendazole also inhibits tubulin polymerization and HIF-1α, VEGF expression, has antioxidant activity, and inhibits the glycolytic process in cancer cells [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54965-21-8. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0223R. | |
| Albendazole sulfoxide | Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ricobendazole; Albendazole oxide. CAS No. 54029-12-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-12785. | |
| Albiflorin | Albiflorin, a major constituent contained in peony root, is a monoterpene glycoside with neuroprotective effects. Albiflorin also has anti-inflammatory, antioxidant and antinociceptive effects[1][2]. Uses: Scientific research. Group: Natural products. CAS No. 39011-90-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0037. | |
| ALC-0159 | ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1849616-42-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138300. | |
| ALC-0315 | ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2036272-55-4. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-138170. | |
| Alcaftadine | Alcaftadine (R89674) is a histamine H1 receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis. Alcaftadine is a broad-spectrum antihistamine displaying a high affinity for histamine H1 and H2 receptors and a lower affinity for H4 receptors. Alcaftadine also exhibits modulatory action on immune cell recruitment and mast cell stabilizing effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R89674. CAS No. 147084-10-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17039. | |
| Alcian Blue 8GX | Alcian Blue 8GX is a commonly used phthalocyanine dye that binds to glycoproteins and glycosaminoglycans. Alcian Blue 8GX has a wide range of applications in biological staining, including proteins in brain tumors and DNA in cells and tissues [1] [2] [3] [4]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 33864-99-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-D0001. | |
| Alclometasone dipropionate | Alclometasone dipropionate (Sch 22219) is a steroid compound. Alclometasone dipropionate can be used for the research of dermatitis and skin itch [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sch 22219. CAS No. 66734-13-2. Pack Sizes: 2.5 mg. Product ID: HY-106566. | |
| Alcohol dehydrogenase, Saccharomyces cerevisiae | Alcohol dehydrogenase, Saccharomyces cerevisiae is a dimeric protein in the cytosol of cells. Alcohol dehydrogenase, the key enzyme for alcohol consumption in the body, is the highest expressed in the liver and participates in the detoxification mechanism of environmental alcohol [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 1.1.1.1. CAS No. 9031-72-5. Pack Sizes: 25 KU. Product ID: HY-P2740. | |
| Alcohol oxidase | Alcohol oxidase is a functional enzyme of methanol utilization pathway and can be isolated from yeast peroxisome [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AO; AOX. CAS No. 9073-63-6. Pack Sizes: 50 U; 250 U. Product ID: HY-P2756. | |
| Alda-1 | Alda-1 is a potent and selective ALDH2 agonist, which activates wild-type ALDH2 and restores near wild-type activity to ALDH2*2. Uses: Scientific research. Group: Signaling pathways. CAS No. 349438-38-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-18936. | |
| Aldafermin | Aldafermin (NGM282) is an analog of fibroblast growth factor 19. Aldafermin can be used for the research of nonalcoholic steatohepatitis (NASH) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: NGM282. CAS No. 1616639-03-2. Pack Sizes: 500 μg; 1 mg. Product ID: HY-P99428. | |
| ALDH | ALDH (Aldehyde dehydrogenase (NAD(P))) catalyzes the oxidation of aldehydes into their corresponding carboxylic acids with the concomitant reduction of the cofactor NAD(P) into NAD(P)H, is often used in biochemical studies. The ALDHs are one of many enzyme systems the body utilizes to alleviate aldehyde stress [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aldehyde dehydrogenase (NAD(P)). CAS No. 9028-88-0. Pack Sizes: 25 U. Product ID: HY-P2947. | |
| ALDH1A inhibitor 673A | ALDH1A inhibitor 673A is an ALDH1A inhibitor with IC50s of 246 nM (ALDH1A1), 230 nM (ALDH1A2), 348 nM (ALDH1A3), respectively. ALDH1A inhibitor 673A has little or no inhibitory effect on other ALDH family members. ALDH1A inhibitor 673A induces necroptotic ovarian cancer stem-like cells (CSCs) death. ALDH1A inhibitor 673A induces DNA double stand breaks in cancer cells. ALDH1A inhibitor 673A can be used for the study of ovarian cancer[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALDH1Ai 673A. CAS No. 109437-62-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122912. | |
| Aldicarb sulfone | Aldicarb sulfone(Temik sulfone) is a carbamate insecticide; is a cholinesterase inhibitor which prevents the breakdown of acetylcholine in the synapse. Uses: Scientific research. Group: Signaling pathways. CAS No. 1646-88-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-17530. | |
| Aldolase, Rabbit muscle | Aldolase, Rabbit muscle is a glycolytic enzyme and a component of the VATPase complex. Aldolase causes fructose 1, 6-diphosphate to decompose into dihydroxyacetone and glyceraldehyde 3-phosphate [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fructose-diphosphate aldolase. CAS No. 9024-52-6. Pack Sizes: 100 U; 500 U. Product ID: HY-P2726. | |
| Aldometanib | Aldometanib (LXY-05-029) is an orally active aldolase inhibitor. Aldometanib can activate lysosomal adenosine monophosphate-activated protein kinase (AMPK) and decreases blood glucose. Aldometanib can be used for the research of metabolic homeostasis[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LXY-05-029. CAS No. 2904601-67-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148189. | |
| Aldosterone | Aldosterone is the primary mineralocorticoid. Aldosterone is a steroid hormone, and it is synthesized and secreted in response to renin-angiotensin system activation (RAS) or high dietary potassium by the zona glomerulosa (ZG) of the adrenal cortex. Aldosterone activity is dependent by the binding and activation of the cytoplasmic/nuclear mineralocorticoid receptor (MR) at cellular level [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 52-39-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-113313. | |
| Aldoxorubicin | Aldoxorubicin (INNO-206) is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), which is released from albumin under acidic conditions. Aldoxorubicin (INNO-206) has potent antitumor activities in various cancer cell lines and in murine tumor models. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INNO-206; DOXO-EMCH. CAS No. 1361644-26-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16261. | |
| Aldumastat | Aldumastat (GLPG1972; S201086) is a potent, seletive and orally active ADAMTS-5 (IC50=19 nM) inhibitor, and has 8-fold seletivity over ADAMTS-4 (IC50=156 nM). Aldumastat has anticatabolic activity and is used for osteoarthritis research[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GLPG1972; S201086. CAS No. 1957278-93-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137430. | |
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