MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Aluminum Glycinate | Aluminum Glycinate, an organo-metallic compound, is an antacid. Aluminum Glycinate can be used for the research of indigestion, acid reflux and ulcers [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dihydroxyaluminum Aminoacetate. CAS No. 13682-92-3. Pack Sizes: 10 g; 25 g. Product ID: HY-A0271. |  |
| Aluminum Hydroxide | Aluminum Hydroxide is an orally active main form of aluminum used as adjuvant. Aluminum hydroxide-based adjuvant researches include the repository effect, pro-phagocytic effect, and activation of the pro-inflammatory NLRP3 pathway. Aluminum Hydroxide also acts as adjuvant to compensate low inherent immunogenicity of subunit vaccines [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 21645-51-2. Pack Sizes: 500 mg; 1 g. Product ID: HY-B1521. | |
| Aluminum oxide | Aluminum oxide is a biological molecule. Uses: Scientific research. Group: Signaling pathways. CAS No. 1344-28-1. Pack Sizes: 100 g; 500 g. Product ID: HY-Y0498. | |
| Aluminum phthalocyanine chloride | Aluminum phthalocyanine chloride is a photosensitizer that effectively inhibits the parasite Leishmania amazonensis (the causative agent of cutaneous leishmaniasis) by light-mediated cytolysis. Aluminum phthalocyanine chloride causes parasite morphology and cytolysis of isolated amasilians, while higher photosensitizer concentrations and light intensities are required to induce lysis of mammalian cells. Aluminum phthalocyanine chloride lyses parasites within infected J774 macrophages and can be used to further investigate the study of leishmaniasis [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: AlClPc. CAS No. 14154-42-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129959. | |
| Aluminum potassium sulfate | Aluminum potassium sulfate (Potassium alum) is a biochemical agent that has water purification and antibacterial activity. Aluminum potassium sulfate can be used in the research of microbiology and environmental science [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Potassium alum. CAS No. 10043-67-1. Pack Sizes: 5 g; 10 g; 25 g; 50 g. Product ID: HY-W134301. | |
| ALV2 | ALV2 is a potent and selective Helios molecular glue degrader. ALV2 binds CRBN, with an IC 50 of 0.57 μM. Helios is the zinc-finger transcription factor that can maintain a stable T reg cell phenotype in the inflammatory tumor microenvironment [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2438124-95-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137206. | |
| Alvelestat | Alvelestat (AZD9668) is an orally bioavailable, affinity and selective inhibitor of neutrophil elastase (NE) with a pIC 50 value of 7.9 nM, a K i value of 9.4 nM and a K d value of 9.5 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD9668. CAS No. 848141-11-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15651. | |
| Alverine citrate | Alverine citrate is a 5-HT 1A receptor antagonist, with an IC 50 of 101 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 35459. CAS No. 5560-59-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0500. | |
| Alvespimycin | Alvespimycin (17-DMAG) is a potent inhibitor of Hsp90 , binding to Hsp90 with an EC 50 of 62 ± 29 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 17-DMAG; KOS-1022; NSC 707545. CAS No. 467214-20-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10389. | |
| Alvespimycin hydrochloride | Alvespimycin hydrochloride (17-DMAG hydrochloride; KOS-1022; BMS 826476) is a potent inhibitor of Hsp90 , binding to Hsp90 with EC 50 of 62±29 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 17-DMAG hydrochloride; KOS-1022 hydrochloride; BMS 826476. CAS No. 467214-21-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 100 mg; 200 mg. Product ID: HY-12024. | |
| Alvimopan | Alvimopan (ADL 8-2698) is a potent, selective, orally active and reversible μ-opioid receptor antagonist, with an IC 50 of 1.7 nM. Alvimopan has selectivity for μ-opioid receptor ( K i =0.47 nM) over κ- and δ-opioid receptors ( K i s=100, 12 nM, respectively). Alvimopan can be used for the research of postoperative ileus [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ADL 8-2698; LY 246736. CAS No. 156053-89-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13243. | |
| ALX-5407 hydrochloride | ALX-5407 ((R)-NFPS) hydrochloride is a selective and orally active glycine transporter GlyT1 inhibitor with an IC 50 value of 3 nM. ALX-5407 hydrochloride can be used the research of N-methyl-D-aspartate-receptor function and schizophrenia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-NFPS hydrochloride. CAS No. 200006-08-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-10711A. | |
| AM-001 | AM-001 is a non-competitive inhibitor of Epac1 that blocks the activation of Rap1, a downstream effector of Epac1, in cultured cells. AM-001 can be used in heart disease-related research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 340817-81-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126133. | |
| AM095 | AM095 is a selective LPA 1 receptor antagonist. The IC 50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA 1 -transfected CHO cells is 0.025 and 0.023 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1345614-59-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16039. | |
| AM095 free acid | AM095 (free acid) is a potent LPA1 receptor antagonist with IC 50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1228690-36-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16040. | |
| AM103 | AM 103 is a potent and selective FLAP inhibitor, with an IC 50 value of 4.2 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1147872-22-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14163. | |
| AM251 | AM251 is a selective cannabinoid 1 ( CB1 ) receptor antagonist with an IC 50 of 8 nM. AM251 also acts as a potent GPR55 agonist with an EC 50 of 39 nM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 183232-66-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15443. | |
| AM281 | AM281 is a selective CB1 receptor antagonist with an IC 50 of 9.91 nM. AM281 inhibits CB2 receptor with an IC 50 of 13000 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 202463-68-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13505. | |
| AM3102 | AM3102 is an oleoylethanolamide (OEA) analog. AM3102 is an endogenous high-affinity PPAR-alpha agonist. AM3102 resists enzymatic hydrolysis, activates PPAR-alpha with high potency in vitro, and persistently reduces feeding when administered in vivo either parenterally or orally [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 213182-22-0. Pack Sizes: 5 mg. Product ID: HY-129683. | |
| AM 374 | AM 374 is an fatty acid amide hydrolase (FAAH) inhibitor. AM 374 inhibits amidase activity with an IC 50 value of 13 nM. AM 374 can be used for the research of neurological disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 86855-26-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125967. | |
| AM6545 | AM6545 is a highly selective, brain-free (peripherally active) CB1 receptor antagonist ( K i =1.7 nM). AM6545 inhibits endocannabinoid signaling by competitively antagonizing CB1 receptors, inhibiting CB1-mediated appetite stimulation and inflammatory responses without affecting cAMP levels. AM6545 significantly reduces food intake and body weight in mice, while improving metabolic syndrome-related renal impairment (such as proteinuria, fibrosis) and insulin resistance. AM6545 can be used in the study of obesity and its complications [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1245626-05-4. Pack Sizes: 1 mg. Product ID: HY-110206. | |
| AMA-37 | AMA-37, an Arylmorpholine analog, is ATP-competitive DNA-PK inhibitor, with IC 50 values of 0.27 μM (DNA-PK), 32 μM (p110α), 3.7 μM (p110β), and 22 μM (p110γ), respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 404009-46-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100706. | |
| Amantadine | Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2 , and also inhibits Coronavirus ion channels. Amantadine also has anti- orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-Adamantanamine; 1-Aminoadamantane. CAS No. 768-94-5. Pack Sizes: 500 mg. Product ID: HY-B0402. | |
| Amantadine hydrochloride | Amantadine (1-Adamantanamine) hydrochloride is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine hydrochloride inhibits several ion channels such as NMDA and M2 , and also inhibits Coronavirus ion channels. Amantadine hydrochloride also has anti- orthopoxvirus and anticancer activity. Amantadine hydrochloride can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-Adamantanamine hydrochloride; 1-Adamantylamine hydrochloride; 1-Aminoadamantane hydrochloride. CAS No. 665-66-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g; 50 g. Product ID: HY-B0402A. | |
| Amaranth | Amaranth is an organic azo dye. Amaranth inhibits cellular immune response. Amaranth can be used as a food additive [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Red 27; Azorubin S; FD & C Red Dye No. 2. CAS No. 915-67-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-D0307A. | |
| Amarogentin | Amarogentin is a secoiridoid glycoside that is mainly extracted from Swertia and Gentiana roots. Amarogentin exhibits many biological effects, including anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin exerts hepatoprotective and immunomodulatory effects. Amarogentin promotes apoptosis , arrests G2/M cell cycle and downregulates of PI3K/Akt/mTOR signalling pathways. Amarogentin exerts beneficial vasculo-metabolic effect by activating AMPK [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 21018-84-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2447. | |
| AMAS | AMAS is a nonclaevable heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules. Uses: Scientific research. Group: Signaling pathways. CAS No. 55750-61-3. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-128925. | |
| Amastatin hydrochloride | Amastatin hydrochloride is a slow, tight binding, competitive aminopeptidase (AP) inhibitor with K i values of 0.26 nM, 30 nM, 52 nM for Aeromonas aminopeptidase, cytosolic leucine aminopeptidase, microsomal aminopeptidase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 100938-10-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-115194. | |
| Amatuximab | Amatuximab (MORab-009) is a chimeric, humanized IgG1/k MAb that targets the cell surface mesothelin (MSLN). Mesothelin is a glycosylphosphatidyl inositol (GPI)-anchored membrane glycoprotein, which is present in a restricted set of normal adult tissues such as the mesothelium [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MORab-009. CAS No. 931402-35-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99006. | |
| Ambazone | Ambazone is an orally active membrane active antitumor agent. Ambazone also shows antibacterial and weak antiviral activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 539-21-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-122356A. | |
| Ambenonium chloride | Ambenonium (WIN 8077) chloride is an orally active and reversible inhibitor of Acetyicholinesterase ( AChE ) with high affinity. Ambenonium chloride inhibits human AChE with an IC 50 value of 0.7 nM (hAChE) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WIN 8077 chloride. CAS No. 115-79-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-100919. | |
| Ambrisentan | Ambrisentan is a selective ET type A receptor ( ETAR ) antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BSF 208075; LU 208075. CAS No. 177036-94-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13209. | |
| Ambroxide | Ambroxide is a naturally occurring terpenoid. Ambroxide is one of the key constituents of ambergris. Uses: Scientific research. Group: Natural products. CAS No. 6790-58-5. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N1384. | |
| Ambroxol | Ambroxol (NA-872), an active metabolite of the proagent Bromhexine, has potent expectorant effects. Ambroxol is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol induces lung autophagy and has the potential for Parkinson disease and neuronopathic Gaucher disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NA-872. CAS No. 18683-91-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1039. | |
| Ambroxol hydrochloride | Ambroxol hydrochloride (NA-872 hydrochloride), an active metabolite of the proagent Bromhexine, has potent expectorant effects. Ambroxol hydrochloride is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol hydrochloride induces lung autophagy and has the potential for Parkinson disease and neuronopathic Gaucher disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NA-872 hydrochloride. CAS No. 23828-92-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1039A. | |
| Ambuic acid | Ambuic acid exhibits antimicrobial activity against Staphylococcus aureus , with IC 50 of 43.9 μM for strain ATCC 6538. Ambuic acid is an inhbitor for the biosynthesis of cyclic peptide quorum sensing molecules (quormones) in gram-positive bacteria. Ambuic acid exhibits anti-inflammatory activity through ERK/JNK/MAPK signaling pathway [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Ambuic acid. CAS No. 340774-69-8. Pack Sizes: 500 μg. Product ID: HY-126858. | |
| Amcenestrant | SAR439859 (compound 43d) is an orally active, non-steroidal, and selective estrogen receptor degrader (SERD). SAR439859 is an effective ER antagonist with ER degradation activity, an EC 50 of 0.2 nM. SAR439859 can show potent anti-tumor effects and limited cross-resistance in ER + breast cancer. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAR439859. CAS No. 2114339-57-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133017. | |
| Amcinonide | Amcinonide is a NO inhibitor that inhibits NO release from activated microglia with IC 50 of 3.38 nM. Amcinonide has glucocorticoid receptor affinity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CL-34699. CAS No. 51022-69-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1197. | |
| AMD 3465 hexahydrobromide | AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide) is a potent antagonist of CXCR4 , inhibits binding of 12G5 mAb and CXCL12 AF647 to CXCR4 , with IC 50 s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains ( IC 50 : 1-10 nM), but has no effect on CCR5-using (R5) viruses. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GENZ-644494 hexahydrobromide. CAS No. 185991-07-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15971. | |
| Amenamevir | Amenamevir is a helicase-primase inhibitor which has potent antiviral activity against HSVs with an EC 50 of 14 ng/mL. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASP2151. CAS No. 841301-32-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14809. | |
| Amentoflavone | Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Didemethyl-ginkgetin. CAS No. 1617-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0662. | |
| Ametryn | Ametryn, a member of the Triazine chemical family, is a herbicide which inhibits photosynthesis and other enzymatic processes. Ametryn is effective against annual broadleaf weeds and grasses [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 834-12-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-B0866. | |
| Amezinium methylsulfate | Amezinium metilsulfate has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition ofnoradrenaline and tyramine uptake. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Amezinium metilsulfate; Lu-1631. CAS No. 30578-37-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-A0275. | |
| Amfenac Sodium Hydrate | Amfenac Sodium Hydrate is a COX-2 inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 61618-27-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17479A. | |
| AMG-193 | AMG 193 is an orally active MTA-cooperative PRMT5 inhibitor with antitumor activity. AMG 193, when complexed with MTA, preferentially inhibits the growth of MTAP-deficient tumor cells by inhibiting PRMT5 ( IC 50 =0.107 μM), thereby protecting normal cells with wild-type MTAP [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2790567-82-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153390. | |
| AMG319 | AMG319 is a potent and selective PI3Kδ kinase inhibitor with IC 50 of 18 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1608125-21-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12948. | |
| AMG-337 | AMG-337 is a potent, orally active, selective MET kinase inhibitor with IC 50 values of 1, 1, 4.7, 5, 21.5, 1077 and >4000 nM of WT MET, H1094R MET, M1250T MET, HGF-stimulated pMET (PC3 cells) MET, V1092I MET, Y1230H MET, and D1228H MET, respectively. AMG 337 inhibits the phosphorylation of MET and downstream effectors in MET-amplified cancer cell lines, resulting in an inhibition of MET-dependent cell proliferation and induction of apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1173699-31-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-18696. | |
| AMG 517 | AMG 517 is a potent and selective vanilloid receptor-1 ( TRPV1 ) antagonist with an IC 50 of 0.5 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 659730-32-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10634. | |
| AMG-548 | AMG-548, an orally active and selective p38α inhibitor ( K i=0.5 nM), shows slightly selective over p38β ( K i=36 nM) and >1000 fold selective against p38γ and p38&delta. AMG 548 is also extremely potent in the inhibition of whole blood LPS stimulated TNFα ( IC 50 =3 nM) [1]. AMG-548 inhibits Wnt signaling by directly inhibiting Casein kinase 1 isoforms δ and ε [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 864249-60-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108642. | |
| AMG-548 dihydrochloride | AMG-548 dihydrochloride, an orally active and selective p38α inhibitor ( K i=0.5 nM), shows slightly selective over p38β ( K i=36 nM) and >1000 fold selective against p38γ and p38&delta. AMG-548 dihydrochloride is also extremely potent in the inhibition of whole blood LPS stimulated TNFα ( IC 50 =3 nM) [1]. AMG-548 dihydrochloride inhibits Wnt signaling by directly inhibiting Casein kinase 1 isoforms δ and ε [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2518299-32-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108642B. | |
| AMG 900 | AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor with IC 50 of 5 nM, 4 nM and 1 nM for Aurora A , B and C , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 945595-80-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13253. | |
| AMG9810 | AMG9810 is a selective and competitive vanilloid receptor 1 ( TRPV1 ) antagonist with IC 50 values of 24.5 and 85.6 nM for human and rat TRPV1, repectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 545395-94-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101736. | |
| Amibegron hydrochloride | Amibegron hydrochloride is a selective β3-adrenoceptor agonist, with an EC 50 of 3.5 nM for β-adrenoceptor in rat colon; Amibegron hydrochloride has anxiolytic and antidepressant activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR 58611A. CAS No. 121524-09-2. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-103207. | |
| Amicarbazone | Amicarbazone (BAY-MKH3586; BAY314666) becomes an effective inhibitor of photosynthetic electron transport by binding to the Qb site of photosystem II (PSII); it is a herbicide with broad-spectrum weed control. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY314666; BAY-MKH 3586. CAS No. 129909-90-6. Pack Sizes: 100 mg. Product ID: HY-17513. | |
| Amidase | Amidases, a member of nitrilase superfamily, catalyzes the hydrolysis of an amide, leading to the formation of carboxylic acid and ammonia. Amidases contain a conserved stretch of approximately 130 amino acids known as the AS sequence, and play a role in important metabolic processes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9012-56-0. Pack Sizes: 250 U; 1 KU. Product ID: HY-P2736. | |
| Amidosulfuron | Amidosulfuron is a herbicide. Amidosulfuron targets acetohydroxyacid synthase (AHAS) , is highly effective against dicot broad-leaf weeds [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120923-37-7. Pack Sizes: 10 mg; 50 mg. Product ID: HY-B1912. | |
| Amifampridine | Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (K v ) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3,4-Diaminopyridine. CAS No. 54-96-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-14946. | |
| Amifloxacin | Amifloxacin (Win49375) is a synthetic antibacterial agent of the quinolone class. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Win49375. CAS No. 86393-37-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-U00221. | |
| Amifostine | Amifostine (WR2721) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer. Amifostine protects cells from damage by scavenging oxygen-derived free radicals. Amifostine reduces renal toxicity and has antiangiogenic action [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WR2721. CAS No. 20537-88-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0639. | |
| Amifostine trihydrate | Amifostine trihydrate (WR2721 trihydrate) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine trihydrate selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine trihydrate is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer. Amifostine trihydrate protects cells from damage by scavenging oxygen-derived free radicals. Amifostine trihydrate reduces renal toxicity and has antiangiogenic action [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WR2721 trihydrate. CAS No. 112901-68-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0639A. | |
| Amikacin | Amikacin (BAY 41-6551) is a semisynthetic kanamycin analog that is active against most Gram-negative bacteria, including gentamicin- and tobramycin-resistant strains. Significant inhibitory effect. Amikacin is ototoxic and nephrotoxic. Amikacin can be used in bacteriostatic, anti-cancer and analgesic studies [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 41-6551. CAS No. 37517-28-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0509A. | |
| Amikacin disulfate | Amikacin disulfate (BAY 41-6551 dissulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin disulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin disulfate is very active against most Gram-negative bacteria including gentamicin - and tobramycin-resistant strains. Amikacin disulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 41-6551 disulfate. CAS No. 39831-55-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0509B. | |
| Amikacin hydrate | Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin hydrate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin hydrate is very active against most Gram-negative bacteria including gentamicin - and tobramycin-resistant strains. Amikacin hydrate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 41-6551 hydrate. CAS No. 1257517-67-1. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-B0509. | |
| Amikacin sulfate | Amikacin sulfate (BAY 41-6551 sulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin sulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin sulfate is very active against most Gram-negative bacteria including gentamicin - and tobramycin-resistant strains. Amikacin sulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 41-6551 sulfate. CAS No. 149022-22-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-107813. | |
| Amiloride | Amiloride (MK-870) is an inhibitor of both epithelial sodium channel ( ENaC [1] ) and urokinase-type plasminogen activator receptor ( uTPA [2] ). Amiloride is a blocker of polycystin-2 (PC2; TRPP2 [3] ) channel. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-870. CAS No. 2609-46-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0285. | |
| Amiloride hydrochloride | Amiloride hydrochloride (MK-870 hydrochloride) is an inhibitor of both epithelial sodium channel ( ENaC [1] ) and urokinase-type plasminogen activator receptor ( uTPA [2] ). Amiloride hydrochloride is a blocker of polycystin-2 (PC2; TRPP2 [3] ) channel. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-870 hydrochloride. CAS No. 2016-88-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0285A. | |
| Amiloride hydrochloride dihydrate | Amiloride hydrochloride dihydrate (MK-870 hydrochloride dihydrate) is an inhibitor of both epithelial sodium channel ( ENaC [1] ) and urokinase-type plasminogen activator receptor ( uTPA [2] ). Amiloride hydrochloride dihydrate is a blocker of polycystin-2 (PC2; TRPP2 [3] ) channel. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-870 hydrochloride dihydrate. CAS No. 17440-83-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0285B. | |
| Amiloride (hydrochloride) (Standard) | Amiloride (hydrochloride) (Standard) is the analytical standard of Amiloride (hydrochloride). This product is intended for research and analytical applications. Amiloride hydrochloride (MK-870 hydrochloride) is an inhibitor of both epithelial sodium channel ( ENaC [1] ) and urokinase-type plasminogen activator receptor ( uTPA [2] ). Amiloride hydrochloride is a blocker of polycystin-2 (PC2; TRPP2 [3] ) channel. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-870 hydrochloride (Standard). CAS No. 2016-88-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-B0285AR. | |
| Amine-PEG3-Biotin | Amine-PEG3-Biotin is a signal amplification label containing a biotin group and a terminal primary amine group [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 359860-27-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111377. | |
| Amino-3,5-dibromopyrazine | Amino-3,5-dibromopyrazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 3,5-Dibromo-2-pyrazinamine; 3,5-Dibromopyrazin-2-ylamine. CAS No. 24241-18-7. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-79805. | |
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