MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Adinazolam | Adinazolam (U 41123) is a benzodiazepine agonist. Adinazolam, a triazolobenzodiazepine, has dual anxiolytic and antidepressant activities [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: U 41123. CAS No. 37115-32-5. Pack Sizes: 1 mg. Product ID: HY-A0198. |  |
| Adintrevimab | Adintrevimab (ADG 20) is a human IgG1 monoclonal SARS-CoV ( SARS-CoV ) antibody. Adintrevimab inhibits SARS-CoV-2 variants and other SARS-like coronaviruses with pandemic potential [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ADG 20. CAS No. 2516243-54-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99423. | |
| Adiphenine hydrochloride | Adiphenine hydrochloride is a non-competitive inhibitor of nicotinic acetylcholine receptor (nAChR) , with an IC 50 s of 1.9, 1.8, 3.7, and 6.3 μM for α1 , α3β4 , α4β2 , and α4β4 , respectively. Adiphenine hydrochloride has anticonvulsant effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 50-42-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0379A. | |
| Adipic acid | Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism. Uses: Scientific research. Group: Natural products. CAS No. 124-04-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W017522. | |
| Adipic acid-13C6 | Adipic acid- 13 C 6 is the 13 C labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 942037-55-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W017522S1. | |
| Adipic acid (Standard) | Adipic acid (Standard) is the analytical standard of Adipic acid. This product is intended for research and analytical applications. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism. Uses: Scientific research. Group: Natural products. CAS No. 124-04-9. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-W017522R. | |
| AdipoR agonist 1 | AdipoR agonist 1 (Compound 112254) is an agonist for adiponectin receptor ( AdipoR ), which activates the transcriptional regulators like peroxisome proliferator-activated receptors (PPARs), peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α), sirtuin 1 (SIRT1), and adenylate-activated protein kinase (AMPK). AdipoR agonist 1 is utilized in preventive doping research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 949745-75-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-130479. | |
| AdipoRon | AdipoRon is an orally active adiponectin receptor (AdipoR) agonist, binding to AdipoR1 and AdipoR2 with K d s of 1.8 and 3.1 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 924416-43-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15848. | |
| Adjudin | Adjudin is an extensively studied male contraceptive with a superior mitochondria -inhibitory effect. Adjudin is also a potent Cl - channel blocker. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AF-2364. CAS No. 252025-52-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18996. | |
| ADL-5859 hydrochloride | ADL-5859 hydrochloride (compound 20) is a selective and orally active δ opioid receptor (DOR) agonist with an K i and an EC 50 value of 0.84 and 20 nM, respectively. ADL-5859 hydrochloride also shows inhibitory activity to hERG channel with an IC 50 value of 78 μM. ADL-5859 hydrochloride can be used for the research of pain [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 850173-95-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13044. | |
| AD-mix-α | AD-mix-α is a mixture of organic compounds, commonly used to distinguish and identify asymmetric carbon atoms in chiral compounds. It consists of compounds containing catalytically active metals and chiral ligands. AD-mix-α is widely used in various organic synthesis reactions, such as hydrogenation, addition, and carbonylation reactions, to increase yield and reduce the formation of side reaction products. Although it has no direct application in the medical field, it plays an important role in the pharmaceutical industry and chemical research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 153130-59-7. Pack Sizes: 1 g; 5 g. Product ID: HY-24312. | |
| ADPS | ADPS is a kind of new Trinder's reagents, which are high water-soluble aniline derivatives, widely used in diagnostic and biochemical tests. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: ESPAS. CAS No. 82611-88-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-15904. | |
| Adrafinil | Adrafinil (CRL-40028, Olmifon), prodrug of modafinil, is a mild central nervous system stimulant drug used to relieve excessive sleepiness and inattention, Adrafinil is believed to serve as an alpha-1 adrenoceptor agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CRL 40028. CAS No. 63547-13-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17549. | |
| Adrenalone hydrochloride | Adrenalone hydrochloride is an adrenergic agonist used as a topical vasoconstrictor and hemostatic. Adrenalone hydrochloride is an inhibitor of dopamine β oxidase. Adrenalone hydrochloride is chemically similar to known norepinephrine transporter (NET) ligands with an IC 50 of 36.9 μM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 62-13-5. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-B1308. | |
| Adrenic acid | Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) is a naturally polyunsaturated fatty acid in the adrenal gland, brain, kidney, and vasculature. Adrenic Acid can regulate the vascular tone in arteries of the adrenal cortex. Adrenic Acid also is an inflammation enhancer in non-alcoholic fatty liver disease [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: cis-7,10,13,16-Docosatetraenoic acid. CAS No. 28874-58-0. Pack Sizes: 5 mg (300 mM * 50 μL in Ethanol); 10 mg (300 mM * 100 μL in Ethanol). Product ID: HY-W013215. | |
| Adrenochrome | Adrenochrome (Adraxone) is an oxidation product of Epinephrine. Adrenochrome is a potent coronary constricting agent in the rat heart. Adrenochrome can be used for neurological disorder research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Adraxone. CAS No. 54-06-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-116513. | |
| Adrenocorticotropic hormone | Adrenocorticotropic hormone (ACTH) is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone regulates cortisol and androgen production [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: ACTH; Adrenocorticotrophic hormone. CAS No. 9002-60-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-106373. | |
| Adrenocorticotropic Hormone (ACTH) (1-39), human | Adrenocorticotropic Hormone (ACTH) (1-39), human is a melanocortin receptor agonist. Uses: Scientific research. Group: Peptides. Alternative Names: 1-39-Corticotropin (human). CAS No. 12279-41-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1211. | |
| Adrenocorticotropic Hormone (ACTH) (1-39), rat | Adrenocorticotropic Hormone (ACTH) (1-39), rat is a potent melanocortin 2 (MC2) receptor agonist. Uses: Scientific research. Group: Peptides. Alternative Names: ACTH (1-39) (mouse, rat). CAS No. 77465-10-2. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1477. | |
| Adrenocorticotropic Hormone (ACTH) (18-39), human TFA | Adrenocorticotropic Hormone (ACTH) (18-39), human TFA is a corticotropinlike intermediate lobe peptide, which is is produced in the melanotrophs of the intermediate lobe of the pituitary [1]. Uses: Scientific research. Group: Peptides. Alternative Names: CLIP (human) TFA. CAS No. 73724-75-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1476A. | |
| Adrenomedullin (rat) | Adrenomedullin (rat) is an effective vasodilator peptide. Adrenomedullin is actively secreted by endothelial cells (EC) and vascular smooth muscle cells (VSMC) [1]. Uses: Scientific research. Group: Peptides. CAS No. 161383-47-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4853. | |
| Adriforant hydrochloride | Adriforant hydrochloride (PF-3893787 hydrochloride) is a novel histamine H4 receptor antagonist binding affinity ( K i =2.4 nM) and is also a functional ( K i =1.56 nM) antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-3893787 hydrochloride. CAS No. 2096455-90-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19705B. | |
| Adrogolide hydrochloride | Adrogolide hydrochloride (ABT-431 hydrochloride) is a chemically stable prodrug that can convert to the dopamine D1 receptor agonist A-86929. Adrogolide hydrochloride ameliorates the MPTP (HY-15608)-induced Parkinson's Disease in marmoset model, reduces the dyskinesias tendency. Adrogolide hydrochloride reverses Risperidone (HY-11018)-induced cognitive deficits in monkey [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-431 hydrochloride; DAS-431 hydrochloride. CAS No. 166591-11-3. Pack Sizes: 1 mg. Product ID: HY-118956. | |
| Adropin (34-76) (human, mouse, rat) | Adropin (34-76) is a secretory domain of Adropin. Adropin (34-76) can inhibit cAMP level and glucose production in hepatocytes, and has a hypoglycemic effect. Adropin (34-76) plays an antifibrotic role by inhibiting the GLI1 signaling pathway [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1802086-30-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4860. | |
| ADT-OH | ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and upregulates FADD. ADT-OH inhibits FAK/Paxillin. ADT-OH has the potential for the research of cancer diseases [1] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione; ACS 1. CAS No. 18274-81-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109582. | |
| Aducanumab | Aducanumab (BIIB037) is a human monoclonal antibody that selectively targets aggregated amyloid-beta (Aβ). Aducanumab shows brain penetration, and can be used for Alzheimer's disease (AD) research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BIIB037. CAS No. 1384260-65-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9967. | |
| Advantame | Advantame is a non-caloric artificial sweetener, analogue of aspartame, commonly used as a food additive [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 714229-20-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122351A. | |
| ADX-47273 | ADX-47273 is a potent, selective and brain-penetrant mGluR5 positive allosteric modulator (PAM), with an EC 50 of 0.17 μM for potentiation of glutamate (50 nM) response. ADX-47273 has antipsychotic and procognitive activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 851881-60-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13058. | |
| ADX71743 | ADX71743 is a highly selective, noncompetitive and brain-penetrant metabotropic glutamate receptor 7 negative allosteric modulator ( mGlu7 NAM ). ADX71743 has anxiolytic-like activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1431641-29-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-110278. | |
| AEBSF hydrochloride | AEBSF hydrochloride is an irreversible inhibitor of serine proteases , such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. Uses: Scientific research. Group: Signaling pathways. CAS No. 30827-99-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-12821. | |
| AEE788 | AEE788 is an inhibitor of the EGFR and ErbB2 with IC 50 values of 2 and 6 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NVP-AEE 788. CAS No. 497839-62-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10045. | |
| Aegeline | Aegeline, a main alkaloid, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast. Aegeline restores growth of yeast cells suppressed by either αsyn or Bax. Antioxidant activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 456-12-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W042156. | |
| Aerobactin | Aerobactin is a siderophore produced by bacteria. Aerobactin is a highly potent pathogenic factor [1]. Uses: Scientific research. Group: Natural products. CAS No. 26198-65-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-122280. | |
| AF-353 | AF-353 (Ro-4) is a potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist, with a pIC 50 of 8.0 for both human and rat P2X3, and with a pIC 50 of 7.3 for human P2X2/3 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro-4. CAS No. 865305-30-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14483. | |
| Afabicin | Afabicin (Debio 1450) is the proagent of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI , an enzyme critical to fatty acid biosynthesis in staphylococci. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Debio 1450; AFN-1720. CAS No. 1518800-35-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-109000. | |
| Afatinib | Afatinib (BIBW 2992) is an orally active, potent and irreversible dual specificity inhibitor of ErbB family ( EGFR and HER2 ), with IC 50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR wt , EGFR L858R , EGFR L858R/T790M and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBW 2992. CAS No. 850140-72-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10261. | |
| Afatinib dimaleate | Afatinib (BIBW 2992) dimaleate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family ( EGFR and HER2 ), with IC 50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR wt , EGFR L858R , EGFR L858R/T790M and HER2, respectively. Afatinib dimaleate can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBW 2992MA2. CAS No. 850140-73-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10261A. | |
| AF-DX 384 | AF-DX 384 is a selective antagonist of M2 and M4 muscarinic acetylcholine receptors ( K i s =6.03 and 10 nM, respectively) [1]. AF-DX 384 reverses deficits in novel object recognition and passive avoidance in aged rats, as well as in young rats with impairments induced by scopolamine [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 118290-26-9. Pack Sizes: 5 mg. Product ID: HY-107652. | |
| Afegostat | Afegostat is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase ( GCase ) in the endoplasmic reticulum (ER) with high affinity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-Isofagomine; Isofagomine. CAS No. 169105-89-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-14829. | |
| Afegostat D-Tartrate | Afegostat D-Tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase ( GCase ) in the endoplasmic reticulum (ER) with high affinity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-Isofagomine D-Tartrate; Isofagomine D-Tartrate. CAS No. 957230-65-8. Pack Sizes: 1 mg. Product ID: HY-14829E. | |
| Afelimomab | Afelimomab (MAK 195F) is an anti-tumor necrosis factor F(ab')2 monoclonal antibody fragment. Afelimomab can be used for the research of sepsis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MAK 195F. CAS No. 156227-98-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99425. | |
| Aficamten | Aficamten (CK-274) is a potent cardiac myosin inhibitor with an IC 50 of 1.4 μM. Aficamten can be used for the research of hypertrophic cardiomyopathy (HCM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CK-274; CK-3773274. CAS No. 2364554-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139465. | |
| Afimetoran | Afimetoran (BMS-986256) is an orally active, selective, and highly bioavailable TLR7/8 antagonist. Afimetoran (BMS-986256) can inhibit TLR7/8 activation of the NF-κB pathway and reverse TLR7 mediated resistance to steroid induced apoptosis in plasma cell like dendritic cells (pDCs). Afimetoran (BMS-986256) can be used for research on inflammation and autoimmune diseases (systemic lupus erythematosus) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-986256. CAS No. 2171019-55-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139567. | |
| Aflatoxicol | Aflatoxin (Aflatoxin R0) is a metabolite of aflatoxin B1 produced from Rhizopus spp [1] , and is mutagenic and carcinogenic mycotoxin [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aflatoxin R0. CAS No. 29611-03-8. Pack Sizes: 1 mg. Product ID: HY-N6695. | |
| Aflibercept | Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR 1 and VEGFR 2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: VEGF Trap; VEGF-TRAPR1R2; VEGF-trapR1. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801. | |
| Aflibercept (VEGF Trap) | Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR 1 and VEGFR 2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801A. | |
| Afloqualone | Afloqualone (HQ-495) is an orally active central muscle relaxant and antivertiginous agent that can increase the sensitivity of GABA receptors in neurons of the lateral vestibular nucleus. Afloqualone (HQ-495) can be used in the research of low back pain and neck-arm-shoulder syndrome [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HQ-495. CAS No. 56287-74-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1833. | |
| Afoxolaner | Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors , inhibiting GABA & glutamate-regulated uptake of chloride ions , resulting in excess neuronal stimulation and death of the arthropod [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1093861-60-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16974. | |
| Afromosin | Afromosin is an isoflavone, that can be isolated from Millettia dielsiana Harms. Afromosin exhibits remarkable tumor inhibitory effects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 550-79-8. Pack Sizes: 1 mg. Product ID: HY-119846. | |
| Afuresertib | Afuresertib (GSK2110183) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with K i s of 0.08/2/2.6 nM for Akt1/Akt2/Akt3, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2110183; LAE002. CAS No. 1047644-62-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15727. | |
| Afuresertib hydrochloride | Afuresertib hydrochloride (GSK 2110183 hydrochloride) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with K i s of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2110183 hydrochloride; LAE002 hydrochloride. CAS No. 1047645-82-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15727A. | |
| AG-1478 | AG-1478 (Tyrphostin AG-1478) is a selective EGFR tyrosine kinase inhibitor with IC 50 of 3 nM. AG-1478 has antiviral effects against HCV and encephalomyocarditis virus (EMCV). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tyrphostin AG-1478; NSC 693255. CAS No. 153436-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13524. | |
| AG 538 | AG 538 is a potent, competitive inhibitor of IGF-1 receptor kinase, with an IC 50 of 400 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133550-18-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135436. | |
| Agarase | Agarase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 37288-57-6. Pack Sizes: 1 KU. Product ID: HY-P2769. | |
| Agarose,Low melting point | Agarose,Low melting point is a kind of agarose, a kind of polysaccharide that can be derived from seaweed. It is commonly used in molecular biology and biochemistry to isolate and purify DNA and RNA fragments. Agarose,Low melting point is a low melting point agarose, which is suitable for the recovery of large DNA fragments and enzymatic reactions in gels and other applications. In addition, it has been used in various techniques, such as pulsed field gel electrophoresis and capillary electrophoresis for analyzing genetic material. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9012-36-6. Pack Sizes: 100 mg; 250 mg. Product ID: HY-W088070A. | |
| Agathisflavone | Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities. Agathisflavone can improve tissue repair in a spinal cord injury model in rats [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 28441-98-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-118383. | |
| Agmatine sulfate | Agmatine sulfate exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor. Uses: Scientific research. Group: Natural products. CAS No. 2482-00-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-101238. | |
| AGN 193109 | AGN 193109 is a retinoid analog, and acts as a specific and highly effective antagonist of retinoic acid receptors (RARs) , with K d s of 2 nM, 2 nM, and 3 nM for RARα , RARβ , and RARγ , respectively. AGN 193109 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. AGN 193109 is the antidote for retinoic acidosis, that ameliorates the skin and mucosal toxicity. Uses: Scientific research. Group: Signaling pathways. CAS No. 171746-21-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00449. | |
| Agnuside | Agnuside is used in the study of asthma, inflammation, and angiogenic diseases. Agnuside is an orally active compound that can be extracted from Vitex negundo [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Agnoside. CAS No. 11027-63-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2518. | |
| Agomelatine | Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with K i s of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively [1]. Agomelatine is a selective 5-HT2C receptor antagonist with pK i s of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: S-20098. CAS No. 138112-76-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17038. | |
| Agomelatine hydrochloride | Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with K i s of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively [1]. Agomelatine hydrochloride is a selective 5-HT2C receptor antagonist with pK i s of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: S-20098 hydrochloride. CAS No. 1176316-99-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17038A. | |
| AH1 | AH1 is an immunodominant antigen derived from the gp70 product of an endogenous MuLV. AH1 behaves as the CTL-immunodominant epitope of CT26 colon carcinoma [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 181272-91-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4193. | |
| AH-7614 | AH-7614 is a potent and selective FFA4 (GPR120) antagonist, with pIC 50 s of 7.1, 8.1, and 8.1 for human, mouse, and rat FFA4, respectively. AH-7614 has selectivity for FFA4 over FFA1 (pIC 50 <4.6). AH-7614 is able to block effects of both the polyunsaturated ω-6 fatty acid linoleic acid and the synthetic FFA4 agonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6326-6-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19996. | |
| AHR-1911 | AHR-1911 (10-Undecen-1-yl-Thiopseudourea Iodide;Isothiuronium) is a thiourea-based anti-inflammatory and anti-tumor agent that has an improving effect on burned skin. AHR-1911 produces histamine-like effects when injected intradermally and may reduce arterial pressure in anesthetized dogs. AHR-1911 inhibits tumor growth and reduces microsomal and C-polysome protein synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 10-Undecen-1-yl-thiopseudourea iodide. CAS No. 22584-04-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107063. | |
| AICAR | AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy , YAP and mitophagy inhibitor [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Acadesine; AICA Riboside. CAS No. 2627-69-2. Pack Sizes: 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13417. | |
| AICAR phosphate | AICAR phosphate (Acadesine phosphate) is an adenosine analog and a AMPK activator. AICAR phosphate regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR phosphate is also an autophagy , YAP and mitophagy inhibitor [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Acadesine phosphate; AICA Riboside phosphate. CAS No. 681006-28-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13417A. | |
| Ailanthone | Ailanthone (Δ13-Dehydrochaparrinone) is a potent inhibitor of both full-length androgen receptor (AR) ( IC 50 =69?nM) and constitutively active truncated AR splice variants (AR 1-651 IC 50 =309?nM). Uses: Scientific research. Group: Natural products. Alternative Names: Δ13-Dehydrochaparrinone. CAS No. 981-15-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1943. | |
| Ajmalicine | Ajmalicine (Raubasine) is a potent adrenolytic agent which preferentially blocks α 1 -adrenoceptor. Ajmalicine is an reversible but non-competitive nicotine receptor full inhibitor, with an IC 50 of 72.3 μM. Ajmalicine also can be used as anti-hypertensive, and serpentine, with sedative activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Raubasine. CAS No. 483-04-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N1919. | |
| Ajmaline | Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC 50 of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cardiorythmine; (+)-Ajmaline. CAS No. 4360-12-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1167. | |
| Ajoene | Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 92285-01-3. Pack Sizes: 1 mg (21.33 mM * 200 μL in Ethyl acetate). Product ID: HY-106784. | |
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