MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Adjudin | Adjudin is an extensively studied male contraceptive with a superior mitochondria -inhibitory effect. Adjudin is also a potent Cl - channel blocker. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AF-2364. CAS No. 252025-52-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18996. |  |
| ADL-5859 hydrochloride | ADL-5859 hydrochloride (compound 20) is a selective and orally active δ opioid receptor (DOR) agonist with an K i and an EC 50 value of 0.84 and 20 nM, respectively. ADL-5859 hydrochloride also shows inhibitory activity to hERG channel with an IC 50 value of 78 μM. ADL-5859 hydrochloride can be used for the research of pain [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 850173-95-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13044. | |
| AD-mix-α | AD-mix-α is a mixture of organic compounds, commonly used to distinguish and identify asymmetric carbon atoms in chiral compounds. It consists of compounds containing catalytically active metals and chiral ligands. AD-mix-α is widely used in various organic synthesis reactions, such as hydrogenation, addition, and carbonylation reactions, to increase yield and reduce the formation of side reaction products. Although it has no direct application in the medical field, it plays an important role in the pharmaceutical industry and chemical research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 153130-59-7. Pack Sizes: 1 g; 5 g. Product ID: HY-24312. | |
| Adomeglivant | Adomeglivant (LY2409021) is a potent, selective glucagon receptor (GluR) allosteric antagonist. Adomeglivant is widely used in the research for type 2 diabetes mellitus[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY2409021. CAS No. 1488363-78-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19904. | |
| ADPS | ADPS is a kind of new Trinder's reagents, which are high water-soluble aniline derivatives, widely used in diagnostic and biochemical tests. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: ESPAS. CAS No. 82611-88-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-15904. | |
| Adrafinil | Adrafinil (CRL-40028, Olmifon), prodrug of modafinil, is a mild central nervous system stimulant drug used to relieve excessive sleepiness and inattention, Adrafinil is believed to serve as an alpha-1 adrenoceptor agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CRL 40028. CAS No. 63547-13-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17549. | |
| Adrenalone hydrochloride | Adrenalone hydrochloride is an adrenergic agonist used as a topical vasoconstrictor and hemostatic. Adrenalone hydrochloride is an inhibitor of dopamine β oxidase. Adrenalone hydrochloride is chemically similar to known norepinephrine transporter (NET) ligands with an IC 50 of 36.9 μM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 62-13-5. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-B1308. | |
| Adrenic acid | Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) is a naturally polyunsaturated fatty acid in the adrenal gland, brain, kidney, and vasculature. Adrenic Acid can regulate the vascular tone in arteries of the adrenal cortex. Adrenic Acid also is an inflammation enhancer in non-alcoholic fatty liver disease [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: cis-7,10,13,16-Docosatetraenoic acid. CAS No. 28874-58-0. Pack Sizes: 5 mg (300 mM * 50 μL in Ethanol); 10 mg (300 mM * 100 μL in Ethanol). Product ID: HY-W013215. | |
| Adrenochrome | Adrenochrome (Adraxone) is an oxidation product of Epinephrine. Adrenochrome is a potent coronary constricting agent in the rat heart. Adrenochrome can be used for neurological disorder research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Adraxone. CAS No. 54-06-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-116513. | |
| Adrenocorticotropic hormone | Adrenocorticotropic hormone (ACTH) is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone regulates cortisol and androgen production [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: ACTH; Adrenocorticotrophic hormone. CAS No. 9002-60-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-106373. | |
| Adrenocorticotropic Hormone (ACTH) (1-39), human | Adrenocorticotropic Hormone (ACTH) (1-39), human is a melanocortin receptor agonist. Uses: Scientific research. Group: Peptides. Alternative Names: 1-39-Corticotropin (human). CAS No. 12279-41-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1211. | |
| Adrenocorticotropic Hormone (ACTH) (1-39), rat | Adrenocorticotropic Hormone (ACTH) (1-39), rat is a potent melanocortin 2 (MC2) receptor agonist. Uses: Scientific research. Group: Peptides. Alternative Names: ACTH (1-39) (mouse, rat). CAS No. 77465-10-2. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1477. | |
| Adrenocorticotropic Hormone (ACTH) (18-39), human TFA | Adrenocorticotropic Hormone (ACTH) (18-39), human TFA is a corticotropinlike intermediate lobe peptide, which is is produced in the melanotrophs of the intermediate lobe of the pituitary [1]. Uses: Scientific research. Group: Peptides. Alternative Names: CLIP (human) TFA. CAS No. 73724-75-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1476A. | |
| Adrenomedullin (AM) (1-52), human TFA | Adrenomedullin (AM) (1-52), human (TFA) affects cell proliferation and angiogenesis in cancer. Uses: Scientific research. Group: Peptides. Alternative Names: Human adrenomedullin-(1-52)-NH2 TFA. Pack Sizes: 500 ?g; 1 mg. Product ID: HY-P1455A. | |
| Adrenomedullin (AM) (22-52), human | Adrenomedullin (AM) (22-52), human, an NH2 terminal truncated adrenomedullin analogue, is an adrenomedullin receptor antagonist, and also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat[1][2]. Uses: Scientific research. Group: Peptides. Alternative Names: 22-52-Adrenomedullin (human). CAS No. 159899-65-7. Pack Sizes: 500 ?g; 1 mg; 5 mg. Product ID: HY-P1471. | |
| Adrenomedullin (rat) | Adrenomedullin (rat) is an effective vasodilator peptide. Adrenomedullin is actively secreted by endothelial cells (EC) and vascular smooth muscle cells (VSMC) [1]. Uses: Scientific research. Group: Peptides. CAS No. 161383-47-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4853. | |
| Adriforant hydrochloride | Adriforant hydrochloride (PF-3893787 hydrochloride) is a novel histamine H4 receptor antagonist binding affinity ( K i =2.4 nM) and is also a functional ( K i =1.56 nM) antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-3893787 hydrochloride. CAS No. 2096455-90-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19705B. | |
| Adrogolide hydrochloride | Adrogolide hydrochloride (ABT-431 hydrochloride) is a chemically stable prodrug that can convert to the dopamine D1 receptor agonist A-86929. Adrogolide hydrochloride ameliorates the MPTP (HY-15608)-induced Parkinson's Disease in marmoset model, reduces the dyskinesias tendency. Adrogolide hydrochloride reverses Risperidone (HY-11018)-induced cognitive deficits in monkey [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-431 hydrochloride; DAS-431 hydrochloride. CAS No. 166591-11-3. Pack Sizes: 1 mg. Product ID: HY-118956. | |
| Adropin (34-76) (human, mouse, rat) | Adropin (34-76) is a secretory domain of Adropin. Adropin (34-76) can inhibit cAMP level and glucose production in hepatocytes, and has a hypoglycemic effect. Adropin (34-76) plays an antifibrotic role by inhibiting the GLI1 signaling pathway [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1802086-30-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4860. | |
| ADS032 | ADS032 is a sulfonylurea compound that is an NLRP1 and NLRP3 inflammasome inhibitor. ADS032 reduces the secretion of inflammatory factors and inhibits the oligomerization of ASC. ADS032 has anti-inflammatory effects in a variety of inflammatory models and can be used in the study of inflammatory diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2757333-37-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156798. | |
| ADT-007 | ADT-007 is a potent and orally active pan-RAS inhibitor with strong anticancer effects. ADT-007 binds RAS in a nucleotide-free conformation to block GTP activation. ADT-007 potently and selectively inhibits the growth of cancer cells with mutated or hyper-activated wild-type RAS isozymes[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1945941-09-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157887. | |
| ADT-OH | ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and upregulates FADD. ADT-OH inhibits FAK/Paxillin. ADT-OH has the potential for the research of cancer diseases [1] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione; ACS 1. CAS No. 18274-81-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109582. | |
| Aducanumab | Aducanumab (BIIB037) is a human monoclonal antibody that selectively targets aggregated amyloid-beta (Aβ). Aducanumab shows brain penetration, and can be used for Alzheimer's disease (AD) research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BIIB037. CAS No. 1384260-65-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9967. | |
| Advantame | Advantame is a non-caloric artificial sweetener, analogue of aspartame, commonly used as a food additive [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 714229-20-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122351A. | |
| ADX-47273 | ADX-47273 is a potent, selective and brain-penetrant mGluR5 positive allosteric modulator (PAM), with an EC 50 of 0.17 μM for potentiation of glutamate (50 nM) response. ADX-47273 has antipsychotic and procognitive activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 851881-60-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13058. | |
| ADX71743 | ADX71743 is a highly selective, noncompetitive and brain-penetrant metabotropic glutamate receptor 7 negative allosteric modulator ( mGlu7 NAM ). ADX71743 has anxiolytic-like activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1431641-29-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-110278. | |
| AEBSF hydrochloride | AEBSF hydrochloride is an irreversible inhibitor of serine proteases , such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. Uses: Scientific research. Group: Signaling pathways. CAS No. 30827-99-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-12821. | |
| AEE788 | AEE788 is an inhibitor of the EGFR and ErbB2 with IC 50 values of 2 and 6 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NVP-AEE 788. CAS No. 497839-62-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10045. | |
| Aegeline | Aegeline, a main alkaloid, mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast. Aegeline restores growth of yeast cells suppressed by either αsyn or Bax. Antioxidant activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 456-12-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W042156. | |
| Aerobactin | Aerobactin is a siderophore produced by bacteria. Aerobactin is a highly potent pathogenic factor [1]. Uses: Scientific research. Group: Natural products. CAS No. 26198-65-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-122280. | |
| AF12198 | AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 μM) or the murine type I receptor (IC50>200 μM). AF12198 inhibits IL-1-induced IL-8 production (IC50=25 nM) and IL-1-induced intercellular adhesion molecule-1 (ICAM-1) expression (IC50=9 nM) in vitro. AF12198 has anti-inflammatory activities and blocks responses to IL-1 in vivo[1]. Uses: Scientific research. Group: Peptides. CAS No. 185413-30-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1110. | |
| AF-353 | AF-353 (Ro-4) is a potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist, with a pIC 50 of 8.0 for both human and rat P2X3, and with a pIC 50 of 7.3 for human P2X2/3 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro-4. CAS No. 865305-30-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14483. | |
| AF38469 | AF38469 is a selective, orally bioavailable Sortilin inhibitor with an IC50 value of 330 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1531634-31-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12802. | |
| AF488 NHS ester TEA | AF488 NHS ester TEA is an amine specific fluorescence probe (?em=525 nm=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization. AF488 exhibits the ?em and ?ex wavelength of 520 nm and 470 nm, respectively[1][2]. Uses: Scientific research. Group: Fluorescent dye. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1730A. | |
| AF647-NHS ester triTEA | AF647-NHS ester is an analogue of Alexa Fluor 647 (AF647), which has excitation wavelength (?ex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection)[1][2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 407627-61-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D1119C. | |
| Afabicin | Afabicin (Debio 1450) is the proagent of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI , an enzyme critical to fatty acid biosynthesis in staphylococci. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Debio 1450; AFN-1720. CAS No. 1518800-35-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-109000. | |
| Afatinib | Afatinib (BIBW 2992) is an orally active, potent and irreversible dual specificity inhibitor of ErbB family ( EGFR and HER2 ), with IC 50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR wt , EGFR L858R , EGFR L858R/T790M and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBW 2992. CAS No. 850140-72-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10261. | |
| Afatinib dimaleate | Afatinib (BIBW 2992) dimaleate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family ( EGFR and HER2 ), with IC 50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR wt , EGFR L858R , EGFR L858R/T790M and HER2, respectively. Afatinib dimaleate can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBW 2992MA2. CAS No. 850140-73-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10261A. | |
| AF-DX 384 | AF-DX 384 is a selective antagonist of M2 and M4 muscarinic acetylcholine receptors ( K i s =6.03 and 10 nM, respectively) [1]. AF-DX 384 reverses deficits in novel object recognition and passive avoidance in aged rats, as well as in young rats with impairments induced by scopolamine [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 118290-26-9. Pack Sizes: 5 mg. Product ID: HY-107652. | |
| Afegostat | Afegostat is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase ( GCase ) in the endoplasmic reticulum (ER) with high affinity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-Isofagomine; Isofagomine. CAS No. 169105-89-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-14829. | |
| Afegostat D-Tartrate | Afegostat D-Tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase ( GCase ) in the endoplasmic reticulum (ER) with high affinity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-Isofagomine D-Tartrate; Isofagomine D-Tartrate. CAS No. 957230-65-8. Pack Sizes: 1 mg. Product ID: HY-14829E. | |
| Afelimomab | Afelimomab (MAK 195F) is an anti-tumor necrosis factor F(ab')2 monoclonal antibody fragment. Afelimomab can be used for the research of sepsis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MAK 195F. CAS No. 156227-98-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99425. | |
| Aficamten | Aficamten (CK-274) is a potent cardiac myosin inhibitor with an IC 50 of 1.4 μM. Aficamten can be used for the research of hypertrophic cardiomyopathy (HCM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CK-274; CK-3773274. CAS No. 2364554-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139465. | |
| Afimetoran | Afimetoran (BMS-986256) is an orally active, selective, and highly bioavailable TLR7/8 antagonist. Afimetoran (BMS-986256) can inhibit TLR7/8 activation of the NF-κB pathway and reverse TLR7 mediated resistance to steroid induced apoptosis in plasma cell like dendritic cells (pDCs). Afimetoran (BMS-986256) can be used for research on inflammation and autoimmune diseases (systemic lupus erythematosus) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-986256. CAS No. 2171019-55-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139567. | |
| Afimkibart | Afimkibart (PF-06480605) is a human IgG1 monoclonal antibody targeting tumor necrosis factor-like ligand 1A (TL1A). Afimkibart can be used in the research of inflammatory bowel disease[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF-06480605; RVT-3101. CAS No. 2911580-96-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990876. | |
| Aflatoxicol | Aflatoxin (Aflatoxin R0) is a metabolite of aflatoxin B1 produced from Rhizopus spp [1] , and is mutagenic and carcinogenic mycotoxin [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aflatoxin R0. CAS No. 29611-03-8. Pack Sizes: 1 mg. Product ID: HY-N6695. | |
| Aflibercept | Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR 1 and VEGFR 2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: VEGF Trap; VEGF-TRAPR1R2; VEGF-trapR1. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801. | |
| Aflibercept (VEGF Trap) | Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR 1 and VEGFR 2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801A. | |
| Afloqualone | Afloqualone (HQ-495) is an orally active central muscle relaxant and antivertiginous agent that can increase the sensitivity of GABA receptors in neurons of the lateral vestibular nucleus. Afloqualone (HQ-495) can be used in the research of low back pain and neck-arm-shoulder syndrome [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HQ-495. CAS No. 56287-74-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1833. | |
| AFM24 | AFM24 is a bispecific antibody with a TandAb structure expressed in CHO, targeting EGFR&Fc-gamma-RIIIA. AFM24 contains a huIgG1-SCFV heavy chain and a ? light chain, with a predicted molecular weight (MW) of 74.5 kDa. The isotype control for AFM24 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990314. | |
| AFM-30a hydrochloride | AFM-30a hydrochloride is a potent protein arginine deiminase 2 (PAD2) inhibitor and has excellent PAD2-selectivity. AFM-30a hydrochloride binds to PAD2 with an EC50 value of 9.5 ?M. AFM-30a hydrochloride also inhibits H3 citrullination with an EC50 value of 0.4 ?M. AFM-30a hydrochloride can be used for the research of certain cancers and a variety of autoimmune diseases including rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125099A. | |
| AFM32a hydrochloride | AFM32a (PAD2-IN-1) hydrochloride, a benzimidazole-based derivative, is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor. AFM32a hydrochloride shows superior selectivity for PAD2 over PAD4 (95-fold) and PAD3 (79-fold)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PAD2-IN-1 hydrochloride. CAS No. 2988594-85-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-136557A. | |
| AFN-1252 | AFN-1252 is an orally active and selective inhibitor of FabI, an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 exhibits exquisite and highly selective activity against Staphylococcus spp. AFN-1252 exhibits typical MIC90 values of ?0.015 ?g/ml against diverse clinical isolates of S. aureus. AFN-1252 is efficacious in a mouse model of septicemia providing 100% protection from an otherwise lethal peritoneal infection of S. aureus Smith[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: API-1252; Debio 1452. CAS No. 620175-39-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16911. | |
| Afoxolaner | Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors , inhibiting GABA & glutamate-regulated uptake of chloride ions , resulting in excess neuronal stimulation and death of the arthropod [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1093861-60-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16974. | |
| Afromosin | Afromosin is an isoflavone, that can be isolated from Millettia dielsiana Harms. Afromosin exhibits remarkable tumor inhibitory effects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 550-79-8. Pack Sizes: 1 mg. Product ID: HY-119846. | |
| Afuresertib | Afuresertib (GSK2110183) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with K i s of 0.08/2/2.6 nM for Akt1/Akt2/Akt3, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2110183; LAE002. CAS No. 1047644-62-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15727. | |
| Afuresertib hydrochloride | Afuresertib hydrochloride (GSK 2110183 hydrochloride) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with K i s of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2110183 hydrochloride; LAE002 hydrochloride. CAS No. 1047645-82-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15727A. | |
| AG-1478 | AG-1478 (Tyrphostin AG-1478) is a selective EGFR tyrosine kinase inhibitor with IC 50 of 3 nM. AG-1478 has antiviral effects against HCV and encephalomyocarditis virus (EMCV). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tyrphostin AG-1478; NSC 693255. CAS No. 153436-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13524. | |
| AG-270 | AG-270 is an allosteric, noncompetitive, first-in-class, reversible and orally active MAT2A inhibitor, with an IC50 of 14 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2201056-66-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138630. | |
| AG490 | AG490 (Tyrphostin AG490) is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tyrphostin AG490; Tyrphostin B42. CAS No. 133550-30-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12000. | |
| AG 538 | AG 538 is a potent, competitive inhibitor of IGF-1 receptor kinase, with an IC 50 of 400 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133550-18-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135436. | |
| Agarase | Agarase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 37288-57-6. Pack Sizes: 1 KU. Product ID: HY-P2769. | |
| Agarose,Low melting point | Agarose,Low melting point is a kind of agarose, a kind of polysaccharide that can be derived from seaweed. It is commonly used in molecular biology and biochemistry to isolate and purify DNA and RNA fragments. Agarose,Low melting point is a low melting point agarose, which is suitable for the recovery of large DNA fragments and enzymatic reactions in gels and other applications. In addition, it has been used in various techniques, such as pulsed field gel electrophoresis and capillary electrophoresis for analyzing genetic material. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9012-36-6. Pack Sizes: 100 mg; 250 mg. Product ID: HY-W088070A. | |
| Agarotetrol | Agarotetrol is a chromone derivative isolated from Agarwood. Uses: Scientific research. Group: Natural products. CAS No. 69809-22-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N1468. | |
| Agathisflavone | Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities. Agathisflavone can improve tissue repair in a spinal cord injury model in rats [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 28441-98-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-118383. | |
| Agatolimod | Agatolimod (ODN 2006), a class B ODN (oligodeoxynucleotide), is a TLR9 agonist. Agatolimod is also an optimal CpG sequence for humans. Agatolimod stimulates very strong production of NO2 and IL-6 in HD11 cells. Agatolimod can be used for breast cancer research. Sequence: 5'-tcgtcgttttgtcgttttgtcgtt-3'[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ODN 2006; PF-3512676; CpG 7909; ODN 7909. CAS No. 525625-52-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-146244. | |
| Agatolimod sodium | Agatolimod sodium (ODN 2006) is a class B CpG ODN and is a TLR9 agonist. Agatolimod sodium can be used as vaccine adjuvant. Agatolimod sodium can be used for the research of cancer. Sequence: 5-TCGTCGTTTTGTCGTTTTGTCGTT-3[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ODN 2006 sodium; ODN 7909 sodium; PF-3512676 sodium; CpG 7909 sodium. CAS No. 541547-35-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150218. | |
| Agerafenib | Agerafenib (CEP-32496; RXDX-105) is a highly potent and orally efficacious inhibitor of BRAFV600E with a Kd of 14 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CEP-32496; RXDX-105. CAS No. 1188910-76-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15200. | |
| AGI-24512 | AGI-24512 is a potent methionine adenosyltransferase 2? (MAT2A) inhibitor, with an IC50 of 8 nM. AGI-24512 triggers DNA damage response. AGI-24512 can block proliferation of MTAP-deleted cancer cells in vitro. AGI-24512 can be used for researching anticancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2201066-53-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-112130. | |
| AGI-6780 | AGI-6780 that potently and selectively inhibits the tumor-associated mutant IDH2R140Q with IC50 of 23±1.7 nM. AGI-6780 is less potent against IDH2WT with IC50 of 190±8.1 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1432660-47-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15734. | |
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