MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Atracurium besylate | Atracurium (BW-33A) besylate is a potent, competitive and non-depolarizing neuromuscular blocking agent. Atracurium besylate also is an AChR receptor antagonist. Atracurium besylate induces bronchoconstriction and neuromuscular blockade. Atracurium besylate promotes astroglial differentiation [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BW-33A. CAS No. 64228-81-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0292A. |  |
| Atranorin | Atranorin is a lichen secondary metabolite. Atranorin inhibits lung cancer cell motility and tumorigenesis by affecting AP-1, Wnt, and STAT signaling and suppressing RhoGTPase activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 479-20-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2907. | |
| Atrasentan | Atrasentan (ABT-627) is an endothelin receptor antagonist with IC 50 of 0.0551 nM for ET A [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-627; (+)-A 127722; A-147627. CAS No. 173937-91-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15403. | |
| Atrasentan hydrochloride | Atrasentan hydrochloride (ABT-627 hydrochloride) is a selective endothelin A receptor antagonist with an IC 50 of 0.0551 nM for ET A [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-627 hydrochloride; (+)-A 127722 hydrochloride; A-147627 hydrochloride. CAS No. 195733-43-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15403A. | |
| Atrazine | Atrazine, a triazine herbicide, is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1912-24-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N7091. | |
| Atrazine-d5 | Atrazine-d 5 is deuterium labeled Atrazine. Atrazine is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 163165-75-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7091S2. | |
| Atrazine (Standard) | Atrazine (Standard) is the analytical standard of Atrazine. This product is intended for research and analytical applications. Atrazine is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1912-24-9. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-N7091R. | |
| Atrimustine | Atrimustine is a conjugate of chlorambucil and β-estradiol benzoate with the antitumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bestrabucil; KM2210. CAS No. 75219-46-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101604. | |
| Atropine methyl bromide | Atropine methyl bromide, a muscarinic receptor (mAChR) antagonist, is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It is introduced for relieving pyloric spasm in infants for its highly polar nature. It penetrates less readily into the central nervous system than atropine [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Methylatropine bromide. CAS No. 2870-71-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112076. | |
| Atropine sulfate | Atropine (Tropine tropate) sulfate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC 50 values of 0.39 and 0.71 nM for Human mAChR M 4 and Chicken mAChR M 4 , respectively. Atropine sulfate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate can be used for research of anti-myopia and bradycardia [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tropine tropate sulfate; DL-Hyoscyamine sulfate; Sulfatropinol. CAS No. 55-48-1. Pack Sizes: 100 mg. Product ID: HY-B1205A. | |
| Atropine sulfate monohydrate | Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC 50 values of 0.39 and 0.71 nM for Human mAChR M 4 and Chicken mAChR M 4 , respectively. Atropine sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate monohydrate can be used for research of anti-myopia and bradycardia [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tropine tropate sulfate monohydrate; DL-Hyoscyamine sulfate monohydrate. CAS No. 5908-99-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0394. | |
| ATTO 488 | ATTO 488 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 500/520 nm. Uses: Scientific research. Group: Fluorescent dye. CAS No. 923585-42-6. Pack Sizes: 1 mg. Product ID: HY-D2000. | |
| Atumelnant | CRN04894 (compound 17h) is an orally active MC2R antagonist that demonstrates in vivo efficacy in rat model of adrenocorticotropic hormone (ACTH)-stimulated corticosterone secretion[1]. CRN04894 binds to human or rat MC2R with K B values of 0.34 nM and 0.23 nM, respsectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CRN04894. CAS No. 2392970-97-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158081. | |
| Atuveciclib | Atuveciclib (BAY-1143572) is a potent and highly selective, oral PTEFb / CDK9 inhibitor. Atuveciclib (BAY-1143572) inhibits CDK9 / CycT1 with an IC 50 of 13 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-1143572. CAS No. 2923012-24-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12871B. | |
| Atuveciclib Racemate | Atuveciclib Racemate (BAY-1143572 Racemate) is the racemate mixture of Atuveciclib. Atuveciclib is a potent and highly selective, oral P-TEFb / CDK9 inhibitor which supresses CDK9 / CycT1 with an IC 50 of 13 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-1143572 Racemate. CAS No. 1414943-88-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12871. | |
| Aucubin | Aucubin, an iridoid glucoside, is isolated from Plantago asiatica , Eucommia ulmoides , the leaves of Aucuba japonica and more recently from butterfly larva. Aucubin has many biological activities, such as antioxidant, anti-aging, anti-inflammatory, antimicrobial, anti-fibrotic, anti-cancer, hepatoprotective, neuroprotective and osteoprotective effects [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 479-98-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0664. | |
| Aucubin (Standard) | Aucubin (Standard) is the analytical standard of Aucubin. This product is intended for research and analytical applications. Aucubin, an iridoid glucoside, is isolated from Plantago asiatica, Eucommia ulmoides, the leaves of Aucuba japonica and more recently from butterfly larva. Aucubin has many biological activities, such as antioxidant, anti-aging, anti-inflammatory, antimicrobial, anti-fibrotic, anti-cancer, hepatoprotective, neuroprotective and osteoprotective effects [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 479-98-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0664R. | |
| AUDA | AUDA (compound 43) is a potent soluble epoxide hydrolase (sEH) inhibitor with IC 50 s of 18 and 69 nM for the mouse and human sEH, respectively [1]. AUDA has anti-inflammatory activity [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 479413-70-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-108570. | |
| Augpenin | Augpenin (Ticarcillin-clavulanic acid mixt.) is a mixture of Ticarcillin (HY-139805) and Clavulanic acid (HY-A0256) in a ratio of 15:1 [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ticarcillin-clavulanic acid mixt. CAS No. 86482-18-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-156264. | |
| Aumitin | Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC 50 s of 0.12 μM and 0.24 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 946293-78-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124726. | |
| AUNP-12 | AUNP-12 (NP-12) is a peptide antagonist of the PD-1 signaling pathway , displays equipotent antagonism toward PD-L1 and PD-L2 in rescue of lymphocyte proliferation and effector functions. AUNP-12 exhibits immune activation, excellent antitumor activity, and potential for better management of immune-related adverse events (irAEs) [1]. Uses: Scientific research. Group: Peptides. Alternative Names: NP-12. CAS No. 1353563-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1812. | |
| Auramine O | Auramine O is a yellow fluorescent dye. Auramine O is used to detect amyloid fibrils. Auramine O promotes lung malignancy. Auramine O is also used to determine algal cell viability and stain acid-fast bacteria [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2465-27-2. Pack Sizes: 50 g; 100 g. Product ID: HY-D0933. | |
| Auranofin | Auranofin (SKF-39162) is a thioredoxin reductase ( TrxR ) inhibitor with an IC 50 of 0.2 μM. Auranofin exhibits antiviral activity against SARS-CoV21 , with a CC 50 of 4.2?μM for monkey kidney Vero E6 cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF-39162. CAS No. 34031-32-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1123. | |
| Aurantiamide | Aurantiamide is an orally active constituent of Portulaca oleracea L and has various biological activities, including antioxidant, antiplatelet, anti-inflammatory, and antitumor activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 58115-31-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2909. | |
| Aurantiamide acetate | Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsin inhibitor isolated from Portulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of inflammatory diseases [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Asperglaucide. CAS No. 56121-42-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2905. | |
| Auraptene | Auraptene is an orally active geranyloxycoumarin that can be isolated from plants in the Brassicaceae family, antibacterial, anti-pathogen, antioxidant, anti-tumor, and neuroprotective effects. Auraptene plays an important role in the treatment of various chronic diseases such as hypertension and cystic fibrosis [1][2]. Uses: Scientific research. Group: Natural products. CAS No. 495-02-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N2388. | |
| Aureobasidin A | Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and antiparasitic activity [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Basifungin. CAS No. 127785-64-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1975. | |
| Aurintricarboxylic acid | Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs , with IC 50 s of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively [1]. Aurintricarboxylic acid is a potent anti-influenza agent by directly inhibiting the neuraminidase [2]. Aurintricarboxylic acid is an inhibitor of topoisomerase II and apoptosis [3]. Aurintricarboxylic acid is a selective inhibitor of the TWEAK-Fn14 signaling pathway [4]. Aurintricarboxylic acid also acts as a cystathionine-lyase (CSE) inhibitor with an IC 50 of 0.6 μM [5]. Aurintricarboxylic acid is a modifier of miRNAs that regulate miRNA function, with an IC 50 of 0.47 μM [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4431-00-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-122575. | |
| Aurora kinase inhibitor-2 | Aurora kinase inhibitor-2 is a selective and ATP-competitive Aurora kinase inhibitor with IC 50 s of 310 nM and 240 nM for Aurora A and Aurora B , respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 331770-21-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112355. | |
| Aurothioglucose | Aurothioglucose (Gold thioglucose), containing monovalent gold ion, is a potent active-site inhibitor of TrxR1 (thioredoxin reductase 1), with an IC 50 of 65 nM. Aurothioglucose inhibits the DNA binding of NF-κB in vitro. Aurothioglucose shows anti-HIV and anti-rheumatic activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Gold thioglucose. CAS No. 12192-57-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-A0068. | |
| Aurothiomalate sodium | Aurothiomalate sodium is a potent and selective oncogenic PKC Ι signaling inhibitor. Aurothiomalate sodium inhibits tumor cell proliferation and not cell apoptosis. Aurothiomalate sodium is a potent thioredoxin reductase (TrxR) inhibitor. Aurothiomalate sodium, an anti-rheumatoid agent, exhibits potent anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 12244-57-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106381. | |
| Autocamtide 2 | Autocamtide 2 is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II ( CaMKII ). It can be used in the CaMKII activity assay. Uses: Scientific research. Group: Peptides. Alternative Names: Autocamtide II. CAS No. 129198-88-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0225. | |
| Autophagy inducer 7 | Autophagy inducer 7 (Compound SSA) is an Autophagy and Apoptosis inducer. Autophagy inducer 7 activates autophagy by inhibiting Akt/mTOR signaling and the expression of downstream proteins. Autophagy inducer 7 suppresses DNA synthesis and causes a G0-G1 cell-cycle arrest. Autophagy inducer 7 inhibits tumor cell growth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 944159-20-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171047. | |
| AV023 | AV023 is a potent inhibitor of ANKRD22. AV023 promotes the expansion of gastrointestinal mucosal epithelial stem cells and indirectly activates the Wnt classical pathway, which helps the recovery of damaged gastrointestinal mucosal tissues in the body (extracted from patent CN111205231B) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1107710-62-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145686. | |
| AV123 | AV123 (compound 12) is a non-cytotoxic RIPK1 inhibitor ( IC 50 =12.12 μM). AV123 blocks the TNF-α-induced necroptotic ( EC 50 =1.7 μM) but not the apoptotic cell death. AV123 can be used in the study of necrotic chronic conditions such as ischemia-reperfusion injury of the brain, heart and kidney, inflammatory diseases, neurodegenerative diseases and infectious diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 233605-81-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151369. | |
| AV5124 | AV5124, a prodrug of AV5116, is an orally active influenza virus cap-dependent endonuclease (CEN) endonuclease inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2417851-93-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164927. | |
| Avacopan | Avacopan (CCX168) is a potent, selective and orally available complement 5a receptor ( C5aR ) inhibitor with an IC 50 of 0.1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCX168. CAS No. 1346623-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17627. | |
| Avadomide | Avadomide is an orally active cereblon modulator. Avadomide modulates cereblon E3 ligase activity, inhibits NF-κB pathway, arrests the cell cycle at G1 phase, and thus induces apoptosis in cancer cell PDAC. Avadomide exhibits potent antitumor and immunomodulatory activities [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC 122. CAS No. 1015474-32-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100507. | |
| Avagacestat | Avagacestat (BMS-708163) is a potent inhibitor of γ-secretase , with IC 50 s of 0.27 nM and 0.30 nM for Aβ42 and Aβ40 inhibition; Avagacestat (BMS-708163) also inhibits NICD (Notch IntraCellular Domain) with IC 50 of 0.84 nM and shows weak inhibition of CYP2C19, with IC 50 of 20 μM. Avagacestat can be used for Alzheimer disease research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-708163. CAS No. 1146699-66-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50845. | |
| Avanafil | Avanafil (TA-1790) is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor with IC 50 values of 5.2 nM, 630 nM, 5700 nM, 6200 nM, 12000 nM, 27000 nM, 51000 nM and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 and PDE-1, respectively. Avanafil activates NO/cGMP/PKG signaling-pathway to decrease loss in BMD, bone atrophy, and oxidative stress. Avanafil inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Avanafil can be used for the research of erectile dysfunction and osteoporosis [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: TA1790. CAS No. 330784-47-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-18252. | |
| Avapritinib | Avapritinib (BLU-285) is a highly potent, selective, and orally active KIT and PDGFRA activation loop mutant kinases inhibitor with IC 50 s of 0.27 and 0.24 nM for KIT D816V and PDGFRA D842V , respectively. Avapritinib (BLU-285) binds the active conformation of the kinase and shows antitumor activity. Avapritinib (BLU-285) attenuates the transport function of both ABCB1 and ABCG2 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-285. CAS No. 1703793-34-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101561. | |
| Avasopasem manganese | Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O 2 *- to hydrogen peroxide (H 2 O 2 ), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GC-4419; M-40419. CAS No. 435327-40-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109110. | |
| Avatrombopag | Avatrombopag (AKR-501) is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist ( EC 50 =3.3 nM). Avatrombopag mimics the biological activities of TPO. Avatrombopag increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKR-501; E5501; YM477. CAS No. 570406-98-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13463. | |
| Avatrombopag hydrochloride | Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist ( EC 50 =3.3 nM). Avatrombopag hydrochloride mimics the biological activities of TPO. Avatrombopag hydrochloride increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag hydrochloride is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKR-501 hydrochloride; E5501 hydrochloride; YM477 hydrochloride. CAS No. 570403-17-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13463B. | |
| Avatrombopag maleate | Avatrombopag maleate (AKR-501) is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist ( EC 50 =3.3 nM). Avatrombopag maleate mimics the biological activities of TPO. Avatrombopag maleate increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag maleate is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKR-501 maleate; E5501 maleate; YM477 maleate. CAS No. 677007-74-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13463A. | |
| Avdoralimab | Avdoralimab (IPH 5401) is a fully human IgGκ monoclonal antibody that targets the complement C5a receptor 1 (C5aR1) that prevents its binding to C5a. Avdoralimab can be used for complement-driven inflammatory diseases and solid tumours research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IPH 5401; Anti-C5aR1 mAb. CAS No. 2226393-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99450. | |
| Avelumab | Avelumab is a fully human IgG1 anti- PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human PD-L1, Human Antibody; MSB 0010718C; MSB0010718C. CAS No. 1537032-82-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-108730. | |
| Avelumab (anti-PD-L1) | Avelumab (anti-PD-L1) is a fully human IgG1 anti- PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1537032-82-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108730A. | |
| Avenanthramide A | Avenanthramide A is a phytoalexin, which can be found in oats ( Avena sativa L. ). Avenanthramide A targets the RNA helicase DDX3 , leads to mitochondrial swelling and increased ROS production, and induces apoptosis in CRC cells. Avenanthramide A exhibits antitumor efficacy in mouse model. Avenanthramide A orally active [1]. Uses: Scientific research. Group: Natural products. CAS No. 108605-70-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-114977. | |
| Avenanthramide C | Avenanthramide C is an orally active avenanthramide that can be isolated from oat seeds. Avenanthramide C decreases the protein expression of cleaved caspase-3 and increases the expression of p-GSK3β(Ser9) and IL-10 levels. Avenanthramide C has the potential for the research of Alzheimers disease [1]. Uses: Scientific research. Group: Natural products. CAS No. 116764-15-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-124344. | |
| Avibactam free acid | Avibactam (NXL-104) free acid is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC 50 s of 8 nM and 5 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NXL-104 free acid. CAS No. 1192500-31-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14879. | |
| Avibactam sodium | Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC 50 s of 8 nM and 5 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NXL-104. CAS No. 1192491-61-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14879A. | |
| Avibactam sodium hydrate | Avibactam sodium (NXL-104) hydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC 50 s of 8 nM and 5 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NXL-104 hydrate. CAS No. 2938989-90-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14879B. | |
| Avibactam tomilopil | Avibactam tomilopil (ARX-1796, AV-006) is an orally active prodrug of Avibactam and a β-lactamase inhibitor. Avibactam tomilopil can be used in the study of diseases such as urinary tract infections [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARX-1796; AV-006. CAS No. 2245880-46-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132987. | |
| Avicularin | Avicularin is an orally active flavonoid. Avicularin inhibits NF-κB (p65) , COX-2 and PPAR-γ activities. Avicularin has anti-inflammatory, anti-infectious anti-allergic, anti-oxidant, hepatoprotective, and anti-tumor activities [1] [3]. Uses: Scientific research. Group: Natural products. CAS No. 572-30-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0222. | |
| Avidin, chiken egg white | Avidin, chicken egg white is a glycoprotein derived from egg protein. Avidin, chicken egg white has excellent affinity with biotin and is often used in combination with biotin for immunoassays to detect the location of antigens in tissues [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1405-69-2. Pack Sizes: 5 mg. Product ID: HY-NP005. | |
| Aviglycine hydrochloride | Aviglycine hydrochloride (ABG-3168) is an inhibitor of ethylene biosynthesis. The use of Aviglycine hydrochloride (ABG-3168) delays the natural flowering of pineapples, reduces fruit drop, and maintains fruit firmness [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABG-3168. CAS No. 55720-26-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W009861. | |
| Aviptadil | Aviptadil is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil can be used for the research of pulmonary fibrosis, pulmonary arterial hypertension (PAH) and SARS-CoV-2 caused respiratory failure, et al [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Peptides. Alternative Names: Vasoactive Intestinal Peptide (human, rat, mouse, rabbit, canine, porcine). CAS No. 40077-57-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-P0012. | |
| Aviptadil acetate | Aviptadil acetate is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil acetate induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil acetate can be used for the research of pulmonary fibrosis, pulmonary arterial hypertension (PAH) and SARS-CoV-2 caused respiratory failure, et al [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Vasoactive Intestinal Peptide acetate salt (human, rat, mouse, rabbit, canine, porcine). CAS No. 1444827-29-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0012A. | |
| Avitinib | Avitinib (Abivertinib) is a third-generation, irreversible and orally active selective EGFR inhibitor, with IC 50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R , EGFR T790M and wild-type EGFR. Avitinib is also a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. Avitinib shows anticancer effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abivertinib; AC0010. CAS No. 1557267-42-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19816. | |
| Avitinib maleate | Avitinib (Abivertinib) maleate is a third-generation, irreversible and orally active selective EGFR inhibitor, with IC 50 values of 0.18 nM, 0.18 nM, 7.68 nM and against EGFR L858R , EGFR T790M and wild-type EGFR. Avitinib maleate is also a BTK inhibitor that induces apoptosis and inhibits phosphorylation of BTK in mantle cell lymphoma. Avitinib maleate shows anticancer effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abivertinib maleate; AC0010 maleate. CAS No. 1557268-88-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19816A. | |
| Avizakimab | Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21 [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BOS161721. CAS No. 2229685-51-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99451. | |
| AVN-101 hydrochloride | AVN-101 hydrochloride is a potent, brain-penetrant and orally active 5-HT7 receptor antagonist ( K i of 153 pM), with slightly lesser potency toward 5-HT6 , 5-HT2A , and 5HT-2C receptors ( K i values of 2.04 nM, 1.56 ?nM, and 1.17? nM, respectively). AVN-101 hydrochloride also exhibits a rather high affinity toward histamine H1 ( K i of 0.58 nM) and adrenergic α2A , α2B , and α2C (Ki= 0.41-3.6 nM) receptors. AVN-101 hydrochloride can be studied in such diseases as general anxiety disorders, depression, schizophrenia, and multiple sclerosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1061354-48-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117046A. | |
| Avobenzone | Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 70356-09-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0316. | |
| Avutometinib | Avutometinib (Ro 5126766) is a first-in-class dual MEK / RAF inhibitor that allosterically inhibits BRAF V600E , CRAF , MEK , and BRAF (IC 50 : 8.2, 56, 160 nM, and 190 nM, respectively). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 5126766; CH5126766. CAS No. 946128-88-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18652. | |
| Axatilimab | Axatilimab (SNDX-6352) is a humanized IgG4 antibody with high affinity to CSF-1R. Axatilimab can be used for the research of chronic graft versus host disease (cGVHD) and neoplastic diseases [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SNDX-6352. CAS No. 2155851-88-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99452. | |
| Axitinib | Axitinib is a multi-targeted tyrosine kinase inhibitor with IC 50 s of 0.1, 0.2, 0.1-0.3, 1.6 nM for VEGFR1 , VEGFR2 , VEGFR3 and PDGFRβ , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-013736. CAS No. 319460-85-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10065. | |
| AZ10606120 dihydrochloride | AZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC 50 of about 10?nM. AZ10606120 dihydrochloride is little or no effect at other P2XR subtypes. AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 607378-18-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-108669. | |
| AZ-1355 | AZ-1355 is an effctive lipid-lowering compound, which also inhibits platelet aggregation in vivo and elevates the prostaglandin I 2 /thromboxane A 2 ratio in vitro. Uses: Scientific research. Group: Signaling pathways. CAS No. 75451-07-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101692. | |
| AZ20 | AZ20 is a potent and selective inhibitor of ATR with an IC 50 of 5 nM, and has 8-fold selectivity against mTOR (IC 50 =38 nM). Uses: Scientific research. Group: Signaling pathways. CAS No. 1233339-22-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15557. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.