MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Baccatin III | Baccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs [1]. Uses: Scientific research. Group: Natural products. CAS No. 27548-93-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N6985. |  |
| Bacitracin | Bacitracin is a polypeptide antibiotic against staphylococcal and pathogenic protozoa infections. Bacitracin inhibits cell wall biosynthesis and permeability through binding to the undecaprenyl pyrophosphate. Bacitracin inhibits macromolecular synthesis. Bacitracin is also a protein disulfide isomerase ( PDI ) inhibitor [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1405-87-4. Pack Sizes: 100 mg. Product ID: HY-107193. | |
| Bacitracin Zinc | Bacitracin Zinc is a complex formed by the binding of Bacitracin (HY-107193) with zinc ions. Bacitracin Zinc is an orally active polypeptide antibiotic with bactericidal properties. Bacitracin Zinc can cause DNA and deoxyribose damage, as well as improve the gut microbiota of broiler and beef cattle [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Zinc bacitracin. CAS No. 1405-89-6. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0278. | |
| Baclofen | Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABA B receptor (GABA B R) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABA B receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1134-47-0. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-B0007. | |
| Baclofen-d4 | Baclofen-d 4 is the deuterium labeled Baclofen. Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1189938-30-4. Pack Sizes: 1 mg. Product ID: HY-B0007S. | |
| Bacoside A3 | Bacoside A3 is a triterpenoid saponin isolated from Bacopa monnieri. Bacoside A3 has neuroprotective activity, downregulating β-amyloid-induced inflammatory responses and inhibiting neuronal apoptosis. Bacoside A3 can be used in the study of Alzheimer's disease [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 157408-08-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N5064. | |
| Bacterial α-Amylase | Bacterial α-Amylase catalyses the hydrolysis of internal α-1,4-glycosidic linkages in starch in low molecular weight products, such glucose, maltose and maltotriose units. Bacterial α-Amylase is often used in biochemical studies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9000-85-5. Pack Sizes: 10 g. Product ID: HY-P2968. | |
| Bafilomycin A1 | Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H + -ATPase ( V-ATPase ) with IC 50 values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: BafA1. CAS No. 88899-55-2. Pack Sizes: 100 μg; 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-100558. | |
| Bafilomycin D | Bafilomycin D is a specific inhibitor of vacuolar-type ATPase ( V-ATPase ). Bafilomycin D has antimicrobial, insecticidal, herbicidal and cytotoxic activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 98813-13-9. Pack Sizes: 1 mg. Product ID: HY-108970. | |
| BAI1 | BAI1 is a selective and allosteric inhibitor of BAX , an apoptosis regulator. BAI1 directly binds to BAX and allosterically inhibits BAX activation. BAI1 has the potential for the research of diseases mediated by BAX-dependent cell death [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 335165-68-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103269. | |
| BAI1 hydrochloride | BAI1 hydrochloride is a selective apoptosis factor BAX allosteric inhibitors. BAI1 hydrochloride binds BAX and allosterically inhibits its activation. BAI1 hydrochloride has the potential to be used in the study of BAX dependent cell death-mediated diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 329349-20-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-110031. | |
| Baicalein | Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor with an IC 50 value of 3.12 μM. Uses: Scientific research. Group: Natural products. Alternative Names: 5,6,7-Trihydroxyflavone. CAS No. 491-67-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0196. | |
| Baicalin | Baicalin, as a flavonoid glycoside, is an allosteric carnitine palmityl transferase 1 ( CPT1 ) activator. Baicalin reduces the expression of NF-κB [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Baicalein 7-O-β-D-glucuronide. CAS No. 21967-41-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0197. | |
| Baicalin (Standard) | Baicalin (Standard) is the analytical standard of Baicalin. This product is intended for research and analytical applications. Baicalin, as a flavonoid glycoside, is an allosteric carnitine palmityl transferase 1 (CPT1) activator. Baicalin reduces the expression of NF-κB [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 21967-41-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0197R. | |
| Bakuchiol | Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 ( UGT2B7 ) [2] and human carboxylesterase 2 ( hCE2 ) [3] , with IC 50 s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory [5] , antibacterial [4] , antitumor [1] therapies, as well as drug metabolism regulation. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-(+)-Bakuchiol. CAS No. 10309-37-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0235. | |
| Balaglitazone | Balaglitazone is a selective partial PPARγ agonist with an EC 50 of 1.351 μM for human PPAR&gamma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DRF 2593; NN 2344. CAS No. 199113-98-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16086. | |
| Balapiravir | Balapiravir (Ro 4588161; R1626) is an orally active proagent of a nucleoside analogue inhibitor of the RNA-dependent RNA polymerase (RdRp) of HCV (R1479; 4'-Azidocytidine). Balapiravir has anti- HCV activity [1] [2] [3]. Balapiravir is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 4588161; R1626. CAS No. 690270-29-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10443. | |
| Balcinrenone | Balcinrenone (AZD9977) is a potent, selective, and orally active mineralocorticoid receptor (MR) modulator. Balcinrenone is used for heart failure, and chronic kidney disease research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD9977. CAS No. 1850385-64-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120274. | |
| Balovaptan | Balovaptan (RG7314) is an orally available, selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with K i s of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors, and is used for the research of autism. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG7314. CAS No. 1228088-30-9. Pack Sizes: 10 mM * 1ML; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109024. | |
| Baloxavir | Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Baloxavir acid; S-033447. CAS No. 1985605-59-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109025A. | |
| Baloxavir marboxil | Baloxavir marboxil (S-033188) is a selective inhibitor of influenza cap-dependent endonuclease. Baloxavir marboxil, a potent antiviral agent, shows activity against influenza A and B virus [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-033188; RG 6152. CAS No. 1985606-14-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-109025. | |
| Balsalazide | Balsalazide is a prodrug of amino salicylic acid that releases mesalamine (HY-15027) in the colon, offering various anti-inflammatory effects in areas of colitis, and it also exerts related anticancer effects by regulating the IL-6/STAT3 pathway [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80573-04-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0667. | |
| Balsalazide sodium hydrate | Balsalazide sodium hydrate is a prodrug of amino salicylic acid that releases mesalamine (HY-15027) in the colon, offering various anti-inflammatory effects in areas of colitis, and it also exerts related anticancer effects by regulating the IL-6/STAT3 pathway [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Balsalazide disodium dihydrate. CAS No. 150399-21-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0667A. | |
| Balstilimab | Balstilimab (AGEN2034) is a fully human monoclonal IgG4 antibody against PD-1 [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AGEN2034. CAS No. 2148321-77-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99457. | |
| BAM 15 | BAM 15 is a mitochondrial protonophore uncoupler. BAM 15 is an oxidative phosphorylation ( OXPHOS ) uncoupler [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 210302-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110284. | |
| BAM(8-22) | BAM(8-22), a proteolytically cleaved product of proenkephalin A and sensory neuron-specific receptor ( SNSR ) agonist, is a potent activator of Mas-related G-protein-coupled receptors ( Mrgprs ), MrgprC11 and hMrgprX1. BAM(8-22) induces scratching in mice in an Mrgpr -dependent manner. In addition, BAM(8-22) has an analgesic effect and can also inhibit the activation of microglia [1] [2] [3] [4]. Uses: Scientific research. Group: Peptides. CAS No. 412961-36-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1241. | |
| Bambuterol hydrochloride | Bambuterol hydrochloride ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a proagent of terbutaline. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Bambuterol hydrochloride; KWD-2183 hydrochloride. CAS No. 81732-46-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17501A. | |
| Bamlanivimab | Bamlanivimab (Anti-Human SARS-CoV-2) is the first COVID-19 monoclonal antibody (mAb) to be granted Emergency Use Authorization (EUA) in November 2020 by the U.S. Food and agent Administration (FDA). However, Bamlanivimab is withdrawn in April 2021 following the rise of SARS-CoV-2 virus variants resistant to Bamlanivimab [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human SARS-CoV-2. CAS No. 2423943-37-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99344. | |
| Bapineuzumab | Bapineuzumab is an anti-β-amyloid protein (APP) monoclonal antibody. Bapineuzumab can be used for the research of Alzheimers disease (AD) [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 648895-38-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99185. | |
| BAPTA | BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca 2+ release from intracellular stores or influx via Ca 2+ -permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 85233-19-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-100168. | |
| BAPTA tetrapotassium | BAPTA tetrapotassium is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca 2+ release from intracellular stores or influx via Ca 2+ -permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators [1] [2] [4]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 73630-08-7. Pack Sizes: 100 mg; 250 mg. Product ID: HY-100168B. | |
| BAPTA tetrasodium | BAPTA tetrasodium is a selective chelator for calcium. BAPTA tetrasodium, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrasodium is widely used as an intracellular buffer for investigating the effects of Ca 2+ release from intracellular stores or influx via Ca 2+ -permeable channels in the plasma membrane. BAPTA tetrasodium can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 126824-24-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-100168A. | |
| Baptifoline | Baptifoline is an alkaloid isolated from the rhizome of Caulophyllum thalictroides [1]. Uses: Scientific research. Group: Natural products. CAS No. 732-50-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7792. | |
| BAR502 | BAR502 is a dual FXR and GPBAR1 agonist with IC 50 values of 2 μM and 0.4 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1612191-86-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101273. | |
| Bardoxolone | Bardoxolone (RTA 401; CDDO) is a novel nuclear regulatory factor ( NRf-2 ) activator. Bardoxolone is a potent necroptosis inhibitor that inhibits Z-VAD-FMK-induced necroptosis. Bardoxolone methyl enhances the antioxidant system, modulates inflammatory cytokines and inhibits apoptosis in rat kidney, demonstrating inhibition on APAP-induced acute kidney injury (AKI) and analgesic effect. Additionally, Bardoxolone methyl decreases Paclitaxel (PAC) (HY-B0015)-induced mitochondrial damage in neuronal cells. Bardoxolone methyl is promising for the research of chemotherapy-induced neuropathic pain and chronic kidney disease [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDDO; RTA 401. CAS No. 218600-44-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14909. | |
| Bardoxolone methyl | Bardoxolone methyl (NSC 713200; RTA 402; CDDO Methyl ester) is a synthetic triterpenoid compound with potential antineoplastic and anti-inflammatory activities, acting as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RTA 402; NSC 713200; CDDO Methyl ester. CAS No. 218600-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13324. | |
| Baricitinib | Baricitinib (LY3009104; INCB028050) is a selective and orally bioavailable JAK1 and JAK2 inhibitor with IC 50 s of 5.9 nM and 5.7 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY3009104; INCB028050. CAS No. 1187594-09-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15315. | |
| Baricitinib phosphate | Baricitinib phosphate (LY3009104 phosphate; INCB028050 phosphate) is a selective orally bioavailable JAK1 / JAK2 inhibitor with IC 50 of 5.9 nM and 5.7 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY3009104 phosphate; INCB028050 phosphate. CAS No. 1187595-84-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15315A. | |
| Barium diphenylamine-4-sulfonate | Barium diphenylamine-4-sulfonate can be employed as an intermediate in pharmaceutical manufacturing and in chemical research, and serves as a dosing agent in analytical testing [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 6211-24-1. Pack Sizes: 1 g; 5 g. Product ID: HY-W087892. | |
| Barnidipine hydrochloride | Barnidipine (Mepirodipine) hydrochloride is an L-type calcium antagonist ( CaA ) with high affinity for [ 3 H] initrendipine binding sites ( K i = 0.21 nmol/L, has selective action against CaA receptors. Barnidipine hydrochloride is an orally active antihypertensive agent that can reduce the level of platelet-derived growth factor B-chain mRNA and peripheral vascular resistance [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mepirodipine hydrochloride; YM-09730-5. CAS No. 104757-53-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107322. | |
| Barzolvolimab | Barzolvolimab (CDX 0159) is a humanized anti- KIT IgG1 monoclonal antibody. Barzolvolimab specificity and potently inhibits KIT activation by SCF. Barzolvolimab can reduce skin mast cells and disease activity in chronic inducible urticaria [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CDX-0159; CDX-0158. CAS No. 2438203-51-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99462. | |
| Basiliximab | Basiliximab (CHI 621) is a recombinant chimeric murine/human IgG1 monoclonal anti- interleukin-2 receptor antibody. Basiliximab can be used for the research of renal transplantation [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CHI 621. CAS No. 179045-86-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108852. | |
| Basimglurant | Basimglurant (RG7090) is a potent, selective and orally available mGlu5 negative allosteric modulator with a K d of 1.1 nM [1]. Basimglurant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG7090; CTEP Derivative. CAS No. 802906-73-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15446. | |
| Basmisanil | Basmisanil (RG1662) is a highly selective orally active α subunit-containing GABAA receptors (GABAAα5) negative allosteric modulator (NAMs). Basmisanil can inhibit GABAA-α5 with a K i value of 5 nM and IC 50 value of 8 nM, respectively. Basmisanil can be used for the research of multiple cognitive and psychiatric disorders [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG1662; RO5186582. CAS No. 1159600-41-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16716. | |
| Batabulin | Batabulin (T138067) is an antitumor agent, which binds covalently and selectively to a subset of the β-tubulin isotypes , thereby disrupting microtubule polymerization. Batabulin affects cell morphology and leads to cell-cycle arrest ultimately induces apoptotic cell death [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T138067. CAS No. 195533-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13563. | |
| Batabulin sodium | Batabulin sodium (T138067 sodium) is an antitumor agent, which binds covalently and selectively to a subset of the β-tubulin isotypes , thereby disrupting microtubule polymerization. Batabulin sodium affects cell morphology and leads to cell-cycle arrest ultimately induces apoptotic cell death [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T138067 sodium. CAS No. 195533-98-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13563A. | |
| Bathophenanthrolinedisulfonic acid disodium | Bathophenanthrolinedisulfonic acid disodium salt (BPS) is a colorimetric reagent for iron detection, with a wavelength of 535 nm for iron complex. It can be used for iron determination in aqueous solution systems without the need for extraction solvents. BPS can serve as a precursor to prepare Europium(III) tris(dibenzoylmethanate) bis(bathophenanthrolinedisulfonate) complex and ruthenium(II) tris (bathophenanthrolinedisulfonate), or participate in the catalytic oxidation of 2-hexanol by forming water-soluble complexes with palladium [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 52746-49-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W127790. | |
| Batilol | 3-(Octadecyloxy)propane-1,2-diol is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 544-62-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-W011175. | |
| Batimastat | Batimastat is a potent broad spectrum MMP inhibitor with IC 50 of 3, 4, 4, 6, and 20 nM for MMP-1 , MMP-2 , MMP-9 , MMP-7 and MMP-3 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BB94. CAS No. 130370-60-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13564. | |
| Batoclimab | Batoclimab is a human anti- FcRn monoclonal antibody. Batoclimab can be used for the research of autoimmune diseases mediated by pathogenic IgG antibodies [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HBM9161; IMVT-1401. CAS No. 2187430-05-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99009. | |
| Batoprotafib | Batoprotafib (TNO155) is a potent selective and orally active allosteric inhibitor of wild-type SHP2 ( IC 50 =0.011 μM). Batoprotafib has the potential for the study of RTK-dependent malignancies, especially advanced solid tumors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TNO155. CAS No. 1801765-04-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136173. | |
| Bavisant | Bavisant (JNJ-31001074) is an orally active, potent, brain-penetrating and highly selective antagonist of the histamine H 3 receptor. Bavisant can be used for attention-deficit hyperactivity disorder (ADHD) research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-31001074. CAS No. 929622-08-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-14880. | |
| Bavisant dihydrochloride hydrate | Bavisant dihydrochloride hydrate (JNJ31001074AAC) is an orally active, potent, brain-penetrating and highly selective antagonist of the histamine H 3 receptor. Bavisant dihydrochloride hydrate can be used for attention-deficit hyperactivity disorder (ADHD) research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ31001074AAC; JNJ31001074 dihydrochloride hydrate. CAS No. 1103522-80-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14880B. | |
| Bavituximab | Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity. Bavituximab plus Paclitaxel (HY-B0015) and Carboplatin (HY-17393), have enhanced inhibition on non-small-cell lung cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human Phosphatidylserine Recombinant Antibody. CAS No. 648904-28-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99279. | |
| Baxdrostat | Baxdrostat is a aldosterone synthase inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CIN-107. CAS No. 1428652-17-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132809. | |
| BAY 11-7082 | BAY 11-7082 is an IκBα phosphorylation and NF-κB inhibitor. BAY 11-7082 selectively and irreversibly inhibits the TNF-α-induced phosphorylation of IκB-α, and decreases NF-κB and expression of adhesion molecules. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 ( IC 50 =0.19, 0.96 μM, respectively). BAY 11-7082 inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 11-7821. CAS No. 19542-67-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13453. | |
| BAY 1214784 | BAY 1214784 is a potent, selective, and orally active antagonist of the human gonadotropin-releasing hormone receptor ( hGnRH-R ). BAY 1214784 is a spiroindoline derivative compound. BAY 1214784 effectively lowers plasma luteinizing hormone levels by up to 49%, at the same time being associated with low pharmacokinetic variability and good tolerability. BAY 1214784 has the potential for the research of uterine fibroids [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1631164-25-4. Pack Sizes: 5 mg. Product ID: HY-144863. | |
| BAY-218 | BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC 50 of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AHR antagonist 1. CAS No. 2162982-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111449. | |
| BAY 2416964 | BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC 50 of 341 nM. BAY 2416964 has the potential for solid tumors treatment [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2242464-44-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135829. | |
| BAY 41-2272 | BAY 41-2272 is an orally active and soluble guanylate cyclases ( sGC ) activator, which increases sGC activity by 400-fold in synergy with NO. BAY 41-2272 potently unloaded the heart, increased cardiac output, thus can be used for cardiovascular diseases research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 256376-24-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12376. | |
| BAY-549 | BAY-549 (Azaindole 1) is an orally active and ATP-competitive ROCK inhibitor with IC 50 s of 0.6 and 1.1?nM for human ROCK-1 and ROCK-2 , respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ROCK-IN-2; Azaindole 1; TC-S 7001. CAS No. 867017-68-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10319. | |
| BAY-5516 | BAY-5516 is a inverse-agonist o PPAR G, with the IC 50 value of 6.1±3.6 nM that has anti-tumor effect [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2891706-79-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160160. | |
| BAY-6035 | BAY-6035 is a potent, selective and substrate-competitive inhibitor of SMYD3. BAY-6035 inhibits methylation of MEKK2 peptide with an IC 50 of 88 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2247890-13-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112080. | |
| BAY 60-6583 | BAY 60-6583 is a potent and high-affinity agonist of adenosine A 2B receptor ( EC 50 = 3 nM) over A1, A2A, and A3 receptors. BAY 60-6583 binds to mouse, rabbit, and dog A2BAR with K i values of 750 nM, 340 nM and 330 nM, respectively. BAY 60-6583 has a cardioprotective effect in a myocardial ischemia model [1] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 910487-58-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103171. | |
| BAY-707 | BAY-707 is a substrate-competitive, highly potent and selective inhibitor of MTH1(NUDT1) with an IC 50 of 2.3 nM. BAY-707 has a good pharmacokinetic (PK) profile to other MTH1 compounds and is well-tolerated in mice, but shows a clear lack of in vitro or in vivo anticancer efficacy [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2109805-96-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112081. | |
| BAY-876 | BAY-876 is an orally active and selective glucose transporter 1 (GLUT1) inhibitor with an IC 50 of 2 nM. BAY-876 is >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 is also a potent blocker of glycolytic metabolism and ovarian cancer growth. In addition, BAY-876 can induce the formation of disulfide bonds in actin cytoskeletal proteins, leading to the occurrence of cellular disulfidptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1799753-84-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100017. | |
| Bay K 8644 | Bay K 8644 ((±)-Bay K 8644) is a racemate consisting of two isomers (R)-(+)-Bay-K-8644 and (S)-(-)-Bay-K-8644 [1]. Bay K 8644 is a L-type Ca 2+ channel agonist with an EC 50 of 17.3 nM. Bay K 8644 increases Ca 2+ influx through sarcolemmal Ca 2+ channels by increasing the open time of the channel. Bay K 8644 has vasoconstrictive effects [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Bay K 8644. CAS No. 71145-03-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10588. | |
| Bazedoxifene | Bazedoxifene (TSE-424) is an oral, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM) , with IC 50 s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene can be used for the research of osteoporosis. Bazedoxifene also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSE-424. CAS No. 198481-32-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0031. | |
| Bazedoxifene acetate | Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM) , with IC 50 s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene acetate can be used for the research of osteoporosis. Bazedoxifene acetate also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSE-424 acetate. CAS No. 198481-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0036. | |
| Bazedoxifene (acetate)-B | Bazedoxifene (acetate)-B (TSE-424 (acetate)-B) is the B-crystal form compound of Bazedoxifene acetate (HY-A0036). Bazedoxifene acetate is an orally active, nonsteroidal selective estrogen receptor modulator (SERM), with IC 50 s of 23 nM and 99 nM for ERα and ERβ, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSE-424 (acetate)-B. CAS No. 198481-33-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0036B. | |
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