MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| AR-13324 analog mesylate | AR-13324 analog mesylate is an analog of AR-13324. AR-13324 is an ROCK and norepinephrine transporter (NET) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095432-73-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-19346. |  |
| AR-13503 | AR-13503 (AR-13324 M1 metabolite) is the hydrolytic metabolite of AR-13324 mesylate. AR-13324 is a ROCK kinase and PKC inhibitor with anti-angiogenic and retinal health-improving effects, showing potential for use in retinal disease research[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AR-13324 M1 metabolite. CAS No. 2309668-15-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12798C. | |
| AR-42 | AR-42 (HDAC-42; OSU-HDAC42) is a potent, orally bioavailable pan- HDAC inhibitor ( IC 50 =16 nM). AR-42 induces growth inhibition, cell-cycle arrest, apoptosis , and activation of caspases-3/7. AR-42 promotes hyperacetylation of H3, H4, and alpha-tubulin, and up-regulation of p21. AR-42 shows cytotoxicity against various human cancer cell lines [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HDAC-42; OSU-HDAC42. CAS No. 935881-37-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13265. | |
| AR420626 | AR420626 is a selective agonist of free fatty acid receptor 3 ( FFAR3 ) ( IC 50 =117 nM). AR420626 has anti-inflammatory, anticancer and antidiabetic activities. AR420626 improves neurogenic diarrhea by inhibiting nAChR mediated neural pathways. AR420626 inhibits the growth of HepG2 xenografts and inhibits the proliferation of hepatoma cells by inducing apoptosis. AR420626 also suppresses allergic asthma and eczema and has the ability to activate GPR41 to increase Ca 2+ signal-mediated glucose uptake and improve diabetes [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1798310-55-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116522. | |
| AR7 | AR7 is an atypical RARA/RARα (retinoic acid receptor, alpha) antagonist. AR7 specifically activates chaperone-mediated-autophagy (CMA) activity without affecting macroautophagy [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80306-38-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101106. | |
| AR-9281 | AR9281 (APAU) is a potent, selective and orally active soluble epoxide hydrolase (s-EH) inhibitor. AR-9281 can inhibits human sEH (HsEH) and murine sEH (MsEH) with IC50 values of 13.8 nM and 1.7 nM, respectively. AR9281 can be used for the research of inflammation, hypertension and type 2 diabetes[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APAU. CAS No. 913548-29-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111151. | |
| AR-A014418 | AR-A014418 is a potent, selective and ATP-competitive GSK3? inhibitor (IC50=104 nM; Ki=38 nM)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AR 0133418; GSK 3? inhibitor VIII; AR 014418. CAS No. 487021-52-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10512. | |
| Arabinose | Arabinose is an endogenous metabolite. Uses: Scientific research. Group: Natural products. Alternative Names: (±)?-Arabinose; DL-Arabinose; dl-Arabinose. CAS No. 147-81-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-N2353. | |
| Arabinosylhypoxanthine | Arabinosylhypoxanthine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis , etc [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7013-16-3. Pack Sizes: 5 mg. Product ID: HY-113431. | |
| Arabinoxylan (Medium viscosity) | Arabinoxylan is the main group of hemicellulosic polysaccharides that are present in the cell walls of monocot grass crops. Arabinoxylan consist of a backbone of β-(1→4)-linked xylopyranosyl residues [1]. Uses: Scientific research. Group: Natural products. CAS No. 9040-27-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N15135. | |
| Arachidic acid | Arachidonic acid (Icosanoic acid), an orally active long-chain fatty acid, is present in all mammalian cells, typically esterified to membrane phospholipids, and is one of the most abundant saturated fatty acids present in human tissue. Moreover, Arachidonic acid is an important mediator of inflammation [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Eicosanoic acid. CAS No. 506-30-9. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W004260. | |
| Arachidic acid (Standard) | Arachidic acid (Standard) is the analytical standard of Arachidic acid. This product is intended for research and analytical applications. Arachidonic acid (Icosanoic acid), a long-chain fatty acid, is present in all mammalian cells, typically esterified to membrane phospholipids, and is one of the most abundant polyunsaturated fatty acids present in human tissue [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Eicosanoic acid (Standard). CAS No. 506-30-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W004260R. | |
| Arachidonic acid | Arachidonic acid (Immunocytophyt) is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid improves cognitive response and cardiovascular function [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Immunocytophyt. CAS No. 506-32-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109590. | |
| Arachidonic acid-d11 | Arachidonic acid-d 11 is the deuterium labeled Arachidonic acid. Arachidonic acid is an essential fatty acid and a major constituent of biomembranes[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Immunocytophyt-d11. CAS No. 2692624-11-4. Pack Sizes: 100 μg (3.17 mM * 100 μL in Ethanol). Product ID: HY-109590S2. | |
| Arachidonic acid-d8 | Arachidonic acid-d 8 is the deuterium labeled Arachidonic acid. Arachidonic acid is an essential fatty acid and a major constituent of biomembranes[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Immunocytophyt-d8. CAS No. 69254-37-1. Pack Sizes: 1 mg (32.00 mM * 100 μL in Methyl acetate). Product ID: HY-109590S. | |
| Arachidonic acid sodium salt | Arachidonic acid (Immunocytophyt) sodium salt is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid sodium salt also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid sodium salt improves cognitive response and cardiovascular function [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Immunocytophyt sodium salt. CAS No. 6610-25-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-109590A. | |
| Arachidonic acid (Standard) | Arachidonic acid (Immunocytophyt) (Standard) is the analytical standard of Arachidonic acid (HY-109590). This product is intended for research and analytical applications. Arachidonic acid is an essential fatty acid and a major constituent of biomembranes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Immunocytophyt (Standard). CAS No. 506-32-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109590R. | |
| Arachidonoyl Serinol | Arachidonoyl Serinol, an endogenous cannabimimetic metabolite, is an inhibitor of monoacylglycerol lipase (MAGL). Arachidonoyl Serinol inhibits the hydrolysis of [ 3 H]2-oleoylglycerol and [ 3 H]anandamide with IC 50 s of ~70 μM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 183718-70-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-121476. | |
| Aramisulpride | Aramisulpride is a dopamine D2 receptor and serotonin receptor antagonist used for the research of metabolic disorders [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-(+)-Amisulpride. CAS No. 71675-90-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109167. | |
| Arbemnifosbuvir | Arbemnifosbuvir is a nidovirus DdRp-associated nucleotidyltransferase (NiRAN) domain of non-structural protein 12 (nsp12)-interfering drugs. Arbemnifosbuvir can be used for SARS-CoVs infection research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT-752 free base. CAS No. 1998705-63-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-156597. | |
| Arbutin | Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase , with K i app values of 1.42 mM for monophenolase; 0.9 mM for diphenolase. Arbutin is also used as depigmenting agents [1]. Arbutin is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi , possesses with anti-oxidant, anti-inflammatory and anti-tumor properties [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: β-Arbutin. CAS No. 497-76-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g; 25 g; 50 g. Product ID: HY-N0192. | |
| Arbutin (Standard) | Arbutin (Standard) is the analytical standard of Arbutin. This product is intended for research and analytical applications. Arbutin (β-Arbutin) is a competitive inhibitor of tyrosinase, with Kiapp values of 1.42 mM for monophenolase; 0.9 mM for diphenolase. Arbutin is also used as depigmenting agents [1]. Arbutin is a natural polyphenol isolated from the bearberry plant Arctostaphylos uvaursi, possesses with anti-oxidant, anti-inflammatory and anti-tumor properties [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 497-76-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0192R. | |
| AR-C118925XX | AR-C118925XX is a selective P2Y2 receptor antagonist. AR-C118925XX inhibits ATP-induced IL-6 production and phosphorylation of p38. AR-C118925XX also inhibits Bleomycin (HY-108345)-induced dermal fibrosis in mice. AR-C118925XX also inhibits ATP-induced tumor growth[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 216657-60-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-110126. | |
| ARC12 | ARC12 is a secondary metabolism probe that modulates the production of Streptomyces coelicolor secondary metabolites. ARC12 reduces the production of germicidin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 64433-38-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153611. | |
| AR-C155858 | AR-C155858 is a selective monocarboxylate transporter MCT1 and MCT2 inhibitor with K i s of 2.3 nM and 10 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 496791-37-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13248. | |
| ARC7 | ARC7 can act as a probe for secondary metabolism in S. coelicolor. ARC7 is a tool for studying secondary metabolism and the streptomycete life cycle [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 681212-58-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153610. | |
| Arcaine sulfate | Arcaine (sulfate) is a glutamate NMDA receptor inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 14923-17-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100920. | |
| ARCC-4 | ARCC-4 is a low-nanomolar Androgen Receptor (AR) degrader based on PROTAC, with a DC50 of 5?nM. ARCC-4 is an enzalutamide-based von Hippel-Lindau (VHL)-recruiting AR PROTAC and outperforms enzalutamide. ARCC-4 effectively degrades clinically relevant AR mutants associated with antiandrogen therapy[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1973403-00-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130492. | |
| Arctigenin | Arctigenin ((-)-Arctigenin), a biologically active lignan, can be used as an antitumor agent. Arctigenin exhibits potent antioxidant, anti-inflammatory and antiviral ( influenza A virus ) activities. Arctigenin can be used for the research of metabolic disorders, and central nervous system dysfunctions [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Arctigenin. CAS No. 7770-78-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0035. | |
| Arctiin | Arctiin is an orally active inhibitor of NF-κB. Arctiin suppresses cyclin D1 protein expression in human tumor cells. Arctiin also reduces malondialdehyde and pro-in?ammatory cytokines levels. Arctiin can used in study glomerulonephritis [4] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Arctii; NSC 315527; Arctigenin-4-glucoside. CAS No. 20362-31-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0034. | |
| Ardisicrenoside A | Ardisicrenoside A exhibits anti-cancer activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 160824-52-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8199. | |
| Arecaidine | Arecaidine, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine is a substrate of H + -coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 499-04-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2368. | |
| Arecaidine hydrochloride | Arecaidine hydrochloride, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrochloride is a substrate of H + -coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 6018-28-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N2368A. | |
| Arecoline | Arecoline, a naturally occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline also can induce oxidative stress [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 63-75-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N2364. | |
| Arecoline hydrobromide | Arecoline hydrobromide, a naturally occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: methyl 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxylate hydrobromide. CAS No. 300-08-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0489. | |
| Arformoterol | Arformoterol ((R,R)-Formoterol), the (R,R)-enantiomer of Formoterol, is a long-acting β2-adrenergic receptor (β2-AR) agonist, with a K d of 2.9 nM. Arformoterol can be used for the research of chronic obstructive pulmonary disease (COPD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R,R)-Formoterol. CAS No. 67346-49-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0010A. | |
| Arg-AMS | Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 301351-95-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-112862. | |
| Argatroban | Argatroban (MD-805) is a direct, selective thrombin inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 74863-84-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0375. | |
| Argatroban monohydrate | Argatroban (monohydrate) (MD-805 (monohydrate)) is a direct, selective thrombin inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MD-805 monohydrate; MCI-9038 monohydrate; Argipidine monohydrate. CAS No. 141396-28-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B0375A. | |
| Arginase inhibitor 1 | Arginase inhibitor 1 is a potent inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1345808-25-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15775. | |
| Arginase, Microorganism | Arginase, Microorganism (L-Arginine amidinase) is an enzyme of the urea cycle. Arginase catalyzes the hydrolysis of L-arginine to L-ornithine and urea [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-Arginine amidinase. CAS No. 9000-96-8. Pack Sizes: 1 KU. Product ID: HY-P3190. | |
| Arginine hydrochloride | Arginine hydrochloride is an arginine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 32042-43-6. Pack Sizes: 100 g. Product ID: HY-W014375. | |
| Argininic acid | Argininic acid is an α-amino acid that is used in the biosynthesis of proteins. Uses: Scientific research. Group: Natural products. Alternative Names: L-Argininic Acid. CAS No. 157-07-3. Pack Sizes: 1 mg. Product ID: HY-113079. | |
| Argipressin | Argipressin (Arg8-vasopressin) binds to the V1, V2, V3-vascular arginine vasopressin receptor , with a K d value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1. Uses: Scientific research. Group: Peptides. Alternative Names: Arg8-vasopressin; AVP. CAS No. 113-79-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P0049. | |
| Argireline | Argireline (Acetyl hexapeptide-3) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline significantly inhibits Ca 2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline has antiwrinkle and anti-aging activity [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: Acetyl hexapeptide-3. CAS No. 616204-22-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-P0033. | |
| Arglabin | Arglabin ((+)-Arglabin), a natural product isolated from Artemisia glabella , is a NLRP3 inflammasome inhibitor. Arglabin shows anti-inflammatory and antitumor activities [1]. The antitumor activity of Arglabin proceeds through its inhibition of farnesyl transferase which leads to the activation of RAS proto-oncogene [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Arglabin. CAS No. 84692-91-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16059. | |
| Arimoclomol citrate | Arimoclomol citrate (BRX-220 citrate) is an orally active co-inducer of heat shock proteins ( HSP ) [1]. Arimoclomol citrate protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system [2]. Arimoclomol citrate can be used for the study of Niemann - Pick disease type C. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRX-220 citrate. CAS No. 368860-21-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106443B. | |
| Arimoclomol maleate | Arimoclomol maleate (BRX-220) is an orally active co-inducer of heat shock proteins ( HSP ) [1]. Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system [2].Arimoclomol maleate can be used for the study of Niemann - Pick disease type C. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRX-220. CAS No. 289893-26-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106443A. | |
| Aripiprazole | Aripiprazole (OPC-14597), an atypical antipsychotic, is a potent and high-affinity dopamine D2 receptor partial agonist. Aripiprazole is an inverse agonist at 5-HT2B and 5-HT2A receptors and displays partial agonist actions at 5-HT1A , 5-HT2C , D3 , and D4 receptors. Aripiprazole can be used for the research of schizophrenia and COVID19 [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC-14597. CAS No. 129722-12-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-14546. | |
| Aripiprazole Lauroxil | Aripiprazole lauroxil, an N-acyloxymethyl proagent of Aripiprazole (HY-14546), is a Long-acting injectable (LAI) typical antipsychotic for schizophrenia and a ligand of dopamine receptor D2R/D4R. Aripiprazole lauroxil is cleaved by bodys enzyme esterase to N-hydroxymethyl aripiprazole (plus lauric acid) and then to aripiprazole (plus formaldehyde), no toxicity. Uses: Scientific research. Group: Signaling pathways. CAS No. 1259305-29-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108751. | |
| Aristolochic acid A | Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Aristolochic acid I; TR 1736. CAS No. 313-67-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0510. | |
| Aristolochic acid C | Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A 2 ( PLA2 ) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis [1]. Uses: Scientific research. Group: Natural products. CAS No. 4849-90-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1450. | |
| Aristolochic acid sodium salt | Aristolochic acid sodium salt (Sodium aristolate 1) is a component of some Chinese herbal medicines and is responsible for nephrotoxicity. It is a proagent that is activated by reduction of nitro groups to amines, resulting in the formation of cytotoxic DNA adducts. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Aristolochic acid I sodium; TR 1736 sodium; Sodium aristolochate. CAS No. 10190-99-5. Pack Sizes: 1 mg; 10 mg. Product ID: HY-N0510A. | |
| Aristolochic acid Va | Aristolochic acid Va is a natural compound that can be isolated from Aristolochia plants [1]. Uses: Scientific research. Group: Natural products. CAS No. 108779-46-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N11445. | |
| Arjunolic acid | Arjunolic acid is a saponin isolated from Cyclocarya paliurus and has various biologial activities, including antioxidant, antimicrobial, antibacterial and anti-inflammory activities. Arjunolic acid is also a potent antioxidant and plays an important role in the protection of cells and tissues against deleterious effects of reactive oxygen species [1]. Uses: Scientific research. Group: Natural products. CAS No. 465-00-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2896. | |
| ARL67156 trisodium | ARL67156 (FPL 67156) trisodium is a selective small molecular inhibitor, targeting to ecto-ATPase , CD39 , and CD73. ARL67156 trisodium is also a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with K i s of 11, 18 and 12 μM, respectively. ARL67156 trisodium can be used in the research of calcific aortic valve disease, asthma [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FPL 67156 trisodium. CAS No. 1021868-83-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103265. | |
| ARM1 | ARM1 (4BSA) is a potent aminopeptidase and epoxide hydrolase inhibitor. ARM1 shows aminopeptidase inhibitory activity with an IC 50 7.61 μM and epoxide hydrolase inhibitory activity with an IC 50 12.4 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4BSA. CAS No. 68729-05-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W027340. | |
| ARN19702 | ARN19702 is a selective, orally active, reversible, and brain-penetrant N-acylethanolamine acid amidase (NAAA) inhibitor with an IC50 of 230 nM for human NAAA. ARN19702 has pain relief effects[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1971937-18-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145339. | |
| ARN-3236 | ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2) , with IC 50 s of <1 nM, 21.63 nM and 6.63 nM for SIK2, SIK1 and SIK3, respectively. Has anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613710-01-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120856. | |
| Aromadendrene | Aromadendrene can be isolated from Eucalyptus globulus. Aromadendrene has antimicrobial activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Aromadendrene. CAS No. 489-39-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8411. | |
| Aromatase-IN-2 | Aromatase-IN-2 is a potent aromatase inhibitor with an IC 50 value of 1.5 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 121768-39-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148430. | |
| Arotinoid | Arotinoid (RO 13-6298) is a retinoid, and acts as an orally active and highly potent agonist of retinoic acid receptors ( RARs ) with antipsoriatic effects. Arotinoid has antipapiltoma activity with an ED 50 of 0.05 mg/kg. Arotinoid can be used for the research of skin carcinomas [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 13-6298; Arotinoid ethyl ester. CAS No. 71441-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106735. | |
| Arotinolol | Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker [1]. Arotinolol also shows potency for inhibiting the binding of the radioligand 125 I-ICYP to 5HT 1B -serotonergic receptor sites [2]. Arotinolol is an antihypertensive agent for the treatment of a variety of cardiovascular pathologies as well as non-cardiovascular diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 68377-92-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122537A. | |
| ARP-100 | ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with S1? pocket of MMP-2 and shows anti-invasive properties in an in vitro model of invasion on matrigel. ARP-100 shows the less inhibitory activity towards MMP-1 (>50 ?M), MMP-3 (4.5 ?M), MMP-7 (>50 ?M), and MMP-9 (0.2 ?M)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 704888-90-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103444. | |
| AR-R17779 hydrochloride | AR-R17779 hydrochloride is a potent and selective full agonist of nAChR , with K i s of 92 and 16000 nM for α7 and α4β2 subtype, respectively. AR-R17779 hydrochloride can improve learning and memory in rats. AR-R17779 hydrochloride also has anxiolytic activity. AR-R17779 hydrochloride can reduce inflammation by activating antiinflammatory cholinergic (vagal) pathways [1] [2] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 178419-42-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-135483A. | |
| ARRY-380 analog | ARRY-380 analog, an inhibitor of EGFR (ErbB1) , is extracted from patent WO2015153959A2, compound 249 [1]. ARRY-380 is a potent, selective, ATP-competitive, orally active inhibitor of HER2 [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 937265-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10531. | |
| ARRY-382 | ARRY-382 is a potent, oral and highly selective inhibitor of CSF1R/c-Fms with an IC 50 of 9 nM. ARRY-382 can be used for the research of advanced or metastatic cancers [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1313407-95-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136362. | |
| ARS-1620 | ARS-1620 is an atropisomeric selective KRASG12C inhibitor with desirable pharmacokinetics. Uses: Scientific research. Group: Signaling pathways. CAS No. 1698055-85-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00418. | |
| Arsenazo III | Arsenazo III is a dye useful for detection of micromolar concentrations of ionized Ca 2+. Arsenazo III can be used for determination of thorium, zirconium, uranium and rare earth elements [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1668-00-4. Pack Sizes: 100 mg. Product ID: HY-D0202. | |
| ART0380 | ART0380 is a potent and selective ATR kinase inhibitor. ART0380 has selective antitumor activity that can be used for the research of Ataxia-Telangiectasia Mutated (ATM) aberrant cancers [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2267316-76-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157941. | |
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