MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Arimoclomol citrate | Arimoclomol citrate (BRX-220 citrate) is an orally active co-inducer of heat shock proteins ( HSP ) [1]. Arimoclomol citrate protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system [2]. Arimoclomol citrate can be used for the study of Niemann - Pick disease type C. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRX-220 citrate. CAS No. 368860-21-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106443B. |  |
| Arimoclomol maleate | Arimoclomol maleate (BRX-220) is an orally active co-inducer of heat shock proteins ( HSP ) [1]. Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system [2].Arimoclomol maleate can be used for the study of Niemann - Pick disease type C. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRX-220. CAS No. 289893-26-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106443A. | |
| Aripiprazole | Aripiprazole (OPC-14597), an atypical antipsychotic, is a potent and high-affinity dopamine D2 receptor partial agonist. Aripiprazole is an inverse agonist at 5-HT2B and 5-HT2A receptors and displays partial agonist actions at 5-HT1A , 5-HT2C , D3 , and D4 receptors. Aripiprazole can be used for the research of schizophrenia and COVID19 [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC-14597. CAS No. 129722-12-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-14546. | |
| Aripiprazole Lauroxil | Aripiprazole lauroxil, an N-acyloxymethyl proagent of Aripiprazole (HY-14546), is a Long-acting injectable (LAI) typical antipsychotic for schizophrenia and a ligand of dopamine receptor D2R/D4R. Aripiprazole lauroxil is cleaved by bodys enzyme esterase to N-hydroxymethyl aripiprazole (plus lauric acid) and then to aripiprazole (plus formaldehyde), no toxicity. Uses: Scientific research. Group: Signaling pathways. CAS No. 1259305-29-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108751. | |
| Aristolochic acid A | Aristolochic acid A (Aristolochic acid I; TR 1736) is the main component of plant extract Aristolochic acids, which are found in various herbal plants of genus Aristolochia and Asarum. Aristolochic acid A significantly reduces both activator protein 1 (AP-1) and NF-κB activities. Aristolochic acid A reduces BLCAP gene expression in human cell lines [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Aristolochic acid I; TR 1736. CAS No. 313-67-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0510. | |
| Aristolochic acid C | Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A 2 ( PLA2 ) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis [1]. Uses: Scientific research. Group: Natural products. CAS No. 4849-90-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1450. | |
| Aristolochic acid sodium salt | Aristolochic acid sodium salt (Sodium aristolate 1) is a component of some Chinese herbal medicines and is responsible for nephrotoxicity. It is a proagent that is activated by reduction of nitro groups to amines, resulting in the formation of cytotoxic DNA adducts. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Aristolochic acid I sodium; TR 1736 sodium; Sodium aristolochate. CAS No. 10190-99-5. Pack Sizes: 1 mg; 10 mg. Product ID: HY-N0510A. | |
| Aristolochic acid Va | Aristolochic acid Va is a natural compound that can be isolated from Aristolochia plants [1]. Uses: Scientific research. Group: Natural products. CAS No. 108779-46-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N11445. | |
| Arjunolic acid | Arjunolic acid is a saponin isolated from Cyclocarya paliurus and has various biologial activities, including antioxidant, antimicrobial, antibacterial and anti-inflammory activities. Arjunolic acid is also a potent antioxidant and plays an important role in the protection of cells and tissues against deleterious effects of reactive oxygen species [1]. Uses: Scientific research. Group: Natural products. CAS No. 465-00-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2896. | |
| ARL67156 trisodium | ARL67156 (FPL 67156) trisodium is a selective small molecular inhibitor, targeting to ecto-ATPase , CD39 , and CD73. ARL67156 trisodium is also a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with K i s of 11, 18 and 12 μM, respectively. ARL67156 trisodium can be used in the research of calcific aortic valve disease, asthma [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FPL 67156 trisodium. CAS No. 1021868-83-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103265. | |
| ARM1 | ARM1 (4BSA) is a potent aminopeptidase and epoxide hydrolase inhibitor. ARM1 shows aminopeptidase inhibitory activity with an IC 50 7.61 μM and epoxide hydrolase inhibitory activity with an IC 50 12.4 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4BSA. CAS No. 68729-05-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W027340. | |
| ARN-3236 | ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2) , with IC 50 s of <1 nM, 21.63 nM and 6.63 nM for SIK2, SIK1 and SIK3, respectively. Has anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613710-01-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120856. | |
| Aromadendrene | Aromadendrene can be isolated from Eucalyptus globulus. Aromadendrene has antimicrobial activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Aromadendrene. CAS No. 489-39-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8411. | |
| Aromatase-IN-2 | Aromatase-IN-2 is a potent aromatase inhibitor with an IC 50 value of 1.5 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 121768-39-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148430. | |
| Arotinoid | Arotinoid (RO 13-6298) is a retinoid, and acts as an orally active and highly potent agonist of retinoic acid receptors ( RARs ) with antipsoriatic effects. Arotinoid has antipapiltoma activity with an ED 50 of 0.05 mg/kg. Arotinoid can be used for the research of skin carcinomas [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 13-6298; Arotinoid ethyl ester. CAS No. 71441-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106735. | |
| Arotinolol | Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker [1]. Arotinolol also shows potency for inhibiting the binding of the radioligand 125 I-ICYP to 5HT 1B -serotonergic receptor sites [2]. Arotinolol is an antihypertensive agent for the treatment of a variety of cardiovascular pathologies as well as non-cardiovascular diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 68377-92-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122537A. | |
| AR-R17779 hydrochloride | AR-R17779 hydrochloride is a potent and selective full agonist of nAChR , with K i s of 92 and 16000 nM for α7 and α4β2 subtype, respectively. AR-R17779 hydrochloride can improve learning and memory in rats. AR-R17779 hydrochloride also has anxiolytic activity. AR-R17779 hydrochloride can reduce inflammation by activating antiinflammatory cholinergic (vagal) pathways [1] [2] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 178419-42-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-135483A. | |
| ARRY-380 analog | ARRY-380 analog, an inhibitor of EGFR (ErbB1) , is extracted from patent WO2015153959A2, compound 249 [1]. ARRY-380 is a potent, selective, ATP-competitive, orally active inhibitor of HER2 [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 937265-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10531. | |
| ARRY-382 | ARRY-382 is a potent, oral and highly selective inhibitor of CSF1R/c-Fms with an IC 50 of 9 nM. ARRY-382 can be used for the research of advanced or metastatic cancers [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1313407-95-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136362. | |
| Arsenazo III | Arsenazo III is a dye useful for detection of micromolar concentrations of ionized Ca 2+. Arsenazo III can be used for determination of thorium, zirconium, uranium and rare earth elements [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1668-00-4. Pack Sizes: 100 mg. Product ID: HY-D0202. | |
| ART0380 | ART0380 is a potent and selective ATR kinase inhibitor. ART0380 has selective antitumor activity that can be used for the research of Ataxia-Telangiectasia Mutated (ATM) aberrant cancers [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2267316-76-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157941. | |
| ART26.12 | ART26.12 is an orally active FABP5 inhibitor with anti-cannabinoid properties. ART26.12 effectively prevents and alleviates Oxaliplatin (HY-17371)-induced pain through lipid modulation and cannabinoid receptor activation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2766800-24-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159115. | |
| Arteannuin B | Arteannuin B, No. 2000 can be jointly submitted with the blue material. Arteannuin B had anti-SARS-CoV-2 activity, EC 50 =10.28 μM [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 50906-56-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2016. | |
| Artemether | Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Dihydroqinghaosu methyl ether; Dihydroartemisinin methyl ether; SM224. CAS No. 71963-77-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0402. | |
| Artemisic acid | Artemisinic acid (Qing Hao acid), an amorphane sesquiterpene isolated from Artemisia annua L., possesses a variety of pharmacological activity, such as antimalarial activity, anti-tumor activity, antipyretic effect, antibacterial activity, allelopathy effect and anti-adipogenesis effect [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Qing Hao acid; Artemisinic acid; Arteannuic acid. CAS No. 80286-58-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N1984. | |
| Artemisinin | Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants [1]. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Qinghaosu; NSC 369397. CAS No. 63968-64-9. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg; 1 g. Product ID: HY-B0094. | |
| Artemisitene | Artemisitene, a natural derivative of Artemisinin, is a Nrf2 activator with antioxidant and anticancer activities. Artemisitene activates Nrf2 by decreasing Nrf2 ubiquitination and increasing its stability [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 101020-89-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-122550. | |
| Artemotil | Artemotil (β-Arteether) has antimalarial activity for the treatment of chloroquine-resistant Plasmodium falciparum malaria with an IC 50 of 1.61 nM. Artemotil also has central nervous system (CNS) neurotoxicity and anorectic toxicity in rats, dogs and monkeys [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: β-Arteether; (+)-Arteether; Arteether. CAS No. 75887-54-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0770. | |
| Artepillin C | Artepillin C has gastroprotective, anti-inflammatory, antimicrobial, antioxidant, antitumor and choleretic activity. Artepillin C can be isolated from Brazilian green propolis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 72944-19-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N10319. | |
| Arterolane | Arterolane is an antimalarial agent, with IC 50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OZ 277; RBx 11160. CAS No. 664338-39-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10852. | |
| Artesunate | Artesunate is an inhibitor of both STAT-3 and exported protein 1 ( EXP1 ). Uses: Scientific research. Group: Natural products. CAS No. 88495-63-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-N0193. | |
| Articaine hydrochloride | Articaine hydrochloride (Hoe-045) is an amide agent that can suppress or relieve pain, containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine hydrochloride ameliorates LPS-induced acute kidney injury via inhibition of NF-κB activation and the NLRP3 inflammasome pathway [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hoe-045. CAS No. 23964-57-0. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0516. | |
| ART-IN-1 | ART-IN-1 (compound 7) is a selective PARP inhibitor with IC 50 s of 19, 22, 2.4, >100, 1.1 μM for PARP2, TNKS2, PARP10, PARP14, PARP15, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2418014-98-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-143338. | |
| ar-Turmerone | ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities [1] [2] [3]. ar-Turmerone activates apoptotic protein in human lymphoma U937 cells [3]. ar-Turmerone exerts positive modulation on murine DCs. ar-Turmerone induces NSC proliferation and constitutes a promising therapeutic agent for various neurologic disorders [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-ar-Turmerone. CAS No. 532-65-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N6703. | |
| Arvanil | Arvanil is a ligand for vanilloid receptor 1 (VR1) and cannabinoid 1 (CB1). Arvanil can inhibit spasticity, as a potent neuroprotectant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Vanillylarachidonamide. CAS No. 128007-31-8. Pack Sizes: 5 mg (113.73 mM * 100 μL in Ethanol); 10 mg (113.73 mM * 200 μL in Ethanol). Product ID: HY-103333. | |
| Arzoxifene hydrochloride | Arzoxifene (LY353381) hydrocloride is a selective estrogen receptor modulator that is a potent estrogen antagonist in mammary and uterine tissue while acting as an estrogen agonist to maintain bone density and lower serum cholesterol. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY353381 hydrochloride; SERM III hydrochloride. CAS No. 182133-27-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-13556A. | |
| AS-85 | AS-85 is a potent ASH1L histone methyltransferase inhibitor ( IC 50 =0.6 μM) with anti-leukemic activity. AS-85 strongly binds to the ASH1L SET domain, with the K d value of 0.78?μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2323623-80-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141430. | |
| (-)-Asarinin | (-)-Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb [1]. Uses: Scientific research. Group: Natural products. CAS No. 133-04-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0701. | |
| Asatone | Asatone is an active component isolated from Radix et Rhizoma Asari, with anti-inflammatory effect via activation of NF-κB and donwn regulation of p-MAPK (ERK, JNK and p38) pathways [1]. Uses: Scientific research. Group: Natural products. CAS No. 38451-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N6826. | |
| Ascaridole | Ascaridole is an anthelmintic and also has antimalarial activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 512-85-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-118494. | |
| Asciminib | Asciminib (ABL001) is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC 50 of 0.25 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABL001. CAS No. 1492952-76-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104010. | |
| Asciminib hydrochloride | Asciminib (ABL001) hydrochloride is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC 50 of 0.25 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABL001 hydrochloride. CAS No. 2119669-71-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104010A. | |
| Ascomycin | Ascomycin (Immunomycin; FR-900520; FK520) is an ethyl analog of Tacrolimus (FK506) with strong immunosuppressant properties. Ascomycin is also a macrocyclic polyketide antibiotic with multiple biological activities such as anti-malarial, anti-fungal and anti-spasmodic. Ascomycin prevents graft rejection and has potential for varying skin ailments research [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Immunomycin; FR-900520; FK520. CAS No. 104987-12-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-13557. | |
| Ascorbate oxidase, Cucurbit sp. | Ascorbate oxidase, Cucurbit sp., also known as vitamin C oxidase, is a REDOX enzyme involved in the regulation of extracellular matrix. Ascorbate oxidase catalyzes the reaction of ascorbic acid and oxygen to produce dehydroascorbic acid [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASO, Cucurbit sp. CAS No. 9029-44-1. Pack Sizes: 100 U; 500 U; 1000 U. Product ID: HY-P2742. | |
| Ascorbyl palmitate | Ascorbyl palmitate is an orally active ester formed from ascorbic acid and palmitic acid, used as an antioxidant and food additive. Ascorbyl palmitate in preventing fat and oil oxidation is more efficient than Butylated hydroxyanisole (HY-B1066) and Butylated hydroxytoluene (HY-Y0172). Ascorbyl palmitate mitigates inhibition of collagen synthesis by select calcium and sodium channel blockers. Ascorbyl palmitate induces Apoptosis in human umbilical vein endothelial cells (HUVECs). Ascorbyl palmitate ameliorates inflammatory diseases by inhibition of NLRP3 inflammasome [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: L-Ascorbic acid 6-hexadecanoate; 6-O-Palmitoyl-L-ascorbic acid. CAS No. 137-66-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0987. | |
| Ascrinvacumab | Ascrinvacumab (PF-03446962) is a human IgG2 monoclonal antibody targets ALK-1. Ascrinvacumab shows binding efficiency with human ALK1 with a K d value of 7 nM. Ascrinvacumab can be used for the research of hepatocellular carcinoma (HCC) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-ACVRL1 / ALK-1 Reference Antibody (ascrinvacumab); PF-03446962. CAS No. 1463459-96-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99353. | |
| ASCT2-IN-1 | ASCT2-IN-1 (compound 20k) is an ASCT2 inhibitor with IC 50 values of 5.6 μM and 3.5 μM in cells A549 and HEK293, respectively. ASCT2-IN-1 induces cell apoptosis. ASCT2-IN-1 inhibits tumor growth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3032651-18-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163198. | |
| Asenapine | Asenapine (Org 5222), an atypical antipsychotic, is an antagonist of serotonin receptors ( pK i : 8.4-10.5), adrenoceptors ( pK i : 8.9-9.5), dopamine receptors ( pK i : 8.9-9.4) and histamine receptors ( pK i : 8.2-9.0). Asenapine can be used in the research of schizophrenia and bipolar disorder [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Org 5222. CAS No. 65576-45-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10121. | |
| Asenapine hydrochloride | Asenapine hydrochloride, an antipsychotic, is a 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) and Dopamine (D 2 , D 3 , D 4 ) receptor antagonist with K i values of 0.03-4.0 nM for 5-HT and 1.3, 0.42, 1.1 nM for Dopamine receptor, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1412458-61-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16567. | |
| Asenapine maleate | Asenapine maleate is a 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) and D2 antagonist with K i values of 0.03-4.0 nM, 1.3nM, respectively, and an antipsychotic. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Org 5222 maleate. CAS No. 85650-56-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-11100. | |
| Asfotase alfa | Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2 / knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ENB-0040. CAS No. 1174277-80-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108786. | |
| Asiatic acid | Asiatic acid, a pentacyclic triterpene found in Centella asiatica ( Centella asiatica ), has anticancer activity. Asiatic acid induces apoptosis in melanoma cells and has barrier protective effects on human aortic endothelial cells (HAEC). Asiatic acid also has anti-inflammatory activity and inhibits tumor necrosis factor (TNF)-α-induced endothelial barrier dysfunction. Asiatic acid also inhibits NLRP3 inflammasome activation and NF-κB pathway, effectively inhibits inflammation in rats, and has neuroprotective effects in rat spinal cord injury (SCI) model [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 464-92-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0194. | |
| Asiaticoside | Asiaticoside, a trisaccaride triterpene from Centella asiatica , suppresses TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts; Asiaticoside shows antioxidant, anti-inflammatory, and anti-ulcer properties. Uses: Scientific research. Group: Natural products. CAS No. 16830-15-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0439. | |
| Asimadoline hydrochloride | Asimadoline (EMD-61753) hydrochloride is an orally active, selective and peripherally active κ-opioid agonist with IC 50 s of 5.6 nM (guinea pig) and 1.2 nM (human recombinant). Asimadoline hydrochloride has low permeability across the blood brain barrier and has peripheral anti-inflammatory actions. Asimadoline hydrochloride ameliorates allodynia in diabetic rats and has the potential for irritable bowel syndrome (IBS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EMD-61753 hydrochloride. CAS No. 185951-07-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-107384A. | |
| Asivatrep | Asivatrep (PAC-14028) is a potent and selective transient receptor potential vanilloid type I ( TRPV1 ) antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PAC-14028. CAS No. 1005168-10-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12777. | |
| ASK1-IN-1 | ASK1-IN-1 is a CNS-penetrant ASK1 (apoptosis signal-regulating kinase 1) inhibitor, with good potency (cell IC 50 =138 nM; Biochemical IC 50 =21 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2411382-24-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133554. | |
| ASN007 | ASN007 (ERK-IN-3) is a potent and orally active inhibitor of ERK. ASN007 inhibits ERK1/2 with low single-digit nM IC 50 values. ASN007 can be used for the research of cancers driven by RAS mutations [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ERK-IN-3. CAS No. 2055597-12-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136579. | |
| ASN007 benzenesulfonate | ASN007 (ERK-IN-3) benzenesulfonate is a potent and orally active inhibitor of ERK. ASN007 benzenesulfonate inhibits ERK1/2 with low single-digit nM IC 50 values. ASN007 benzenesulfonate can be used for the research of cancers driven by RAS mutations [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ERK-IN-3 benzenesulfonate. CAS No. 2055597-39-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136579A. | |
| Asoprisnil | Asoprisnil (J867), a selective progesterone receptor modulator, exhibits mixed progesterone agonist and antagonist effects on various progesterone targeted tissues in animal and human [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: J867. CAS No. 199396-76-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-119433. | |
| ASP2535 | ASP2535 is a potent, orally bioavailable, selective, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor. ASP2535 can improve cognitive impairment in animal models of schizophrenia and Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 374886-51-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-110176. | |
| ASP5878 | ASP5878 is an oral active inhibitor of FGFR 1, 2, 3, and 4 , with IC 50 values of 0.47 nM, 0.6 nM, 0.74 nM and 3.5 nM for FGFR 1, 2, 3, and 4 kinase activity. ASP5878 has potential antineoplastic activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1453208-66-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19983. | |
| ASP7663 | ASP7663 is an orally active and selective TRPA1 agonist. ASP7663 exerts both anti-constipation and anti-abdominal pain actions [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1190217-35-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101907. | |
| Asparagusic acid | Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 2224-2-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50730. | |
| Aspartame | Aspartame (SC-18862) is a methyl ester of a dipeptide. Aspartame can be used as a synthetic nonnutritive sweetener [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: SC-18862. CAS No. 22839-47-0. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-B0361. | |
| Aspartame (Standard) | Aspartame (Standard) is the analytical standard of Aspartame. This product is intended for research and analytical applications. Aspartame (SC-18862) is a methyl ester of a dipeptide. Aspartame can be used as a synthetic nonnutritive sweetener [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 22839-47-0. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B0361R. | |
| Aspartate aminotransferase, Genetically engineered bacteria | Aspartate aminotransferase, Genetically engineered bacteria (EC 2.6.1.1) (AST) is a transaminase enzyme, is often used in biochemical studies. Aspartate aminotransferase catalyzes aspartate and alpha-ketoglutarate converts to oxaloacetate and glutamate. Aspartate aminotransferase can be found in cerebrospinal fluid, exudates, and transudates [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 2.6.1.1; GOT; AST. CAS No. 9000-97-9. Pack Sizes: 200 U; 1 KU. Product ID: HY-P3016. | |
| (-)-Aspartic acid | (-)-Aspartic acid is a pyroptosis inhibitor. (-)-Aspartic acid acts as a neurotransmitter and neuromodulator, participates in hormone synthesis and regulation, and plays a role in nervous system development and endocrine system [5]. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-Aspartic acid; D-(-)-Aspartic acid. CAS No. 1783-96-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 25 g; 50 g. Product ID: HY-42068. | |
| Aspartic acid calcium | Aspartic acid calcium (Calcium L-aspartate) is a chelate where calcium is attached to an amino acid naming L-Aspartic acid. L-Aspartic acid is an amino acid and serves as a building block for proteins in the body. Uses: Scientific research. Group: Natural products. Alternative Names: Calcium L-aspartate. CAS No. 10389-09-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N0666B. | |
| Aspergillopepsin I | Aspergillopepsin I (Aspergillus acid protease) is an aspartic endopeptidase that catalyses the hydrolysis of peptide bonds in proteins, with broad specificity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aspergillus acid protease. CAS No. 9025-49-4. Pack Sizes: 5 g. Product ID: HY-P2973. | |
| Asperosaponin VI | Asperosaponin VI, A saponin component from Dipsacus asper , induces osteoblast differentiation through BMP?2/p38 and ERK1/2 pathway [1]. Asperosaponin ? inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB [2]. Uses: Scientific research. Group: Natural products. CAS No. 39524-08-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0265. | |
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