MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Aspirin | Aspirin (Acetylsalicylic Acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2 , with IC 50 values of 5 and 210 μg/mL, respectively. Aspirin induces apoptosis. Aspirin inhibits the activation of NF-κB. Aspirin also inhibits platelet prostaglandin synthetase , and can prevent coronary artery and cerebrovascular thrombosis [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Acetylsalicylic Acid; ASA. CAS No. 50-78-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-14654. |  |
| Aspirin Aluminum | Aspirin Aluminum is a novel intermolecular compound which can inhibit gastrointestinal mucosal disorders induced by NSAIDs (non-steroidal anti-inflammatory agents) extracted from patent WO 2010064441 A1. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aluminum diacetylsalicylate. CAS No. 23413-80-1. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B2175. | |
| Aspirin (Standard) | Aspirin (Standard) is the analytical standard of Aspirin. This product is intended for research and analytical applications. Aspirin (Acetylsalicylic Acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2 , with IC 50 values of 5 and 210 μg/mL, respectively. Aspirin induces apoptosis. Aspirin inhibits the activation of NF-κB. Aspirin also inhibits platelet prostaglandin synthetase , and can prevent coronary artery and cerebrovascular thrombosis [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Acetylsalicylic Acid(Standard); ASA (Standard). CAS No. 50-78-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-14654R. | |
| Aspoxicillin | Aspoxicillin is a broad-spectrum antimicrobial agent against 68 isolates of Actinobacillus pleuropneumoniae with an MIC 90 value of <= 0.05 μg/ml. Aspoxicillin has a long half-life in mouse serum of 55 minutes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 63358-49-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135842. | |
| ASS234 | ASS234 is a potent monoamino oxidase (MAO) inhibitor with IC 50 s of 5.2 nM and 43 nM for MAO-A and MAO-B, respectively. ASS234 also inhibits AChE and BuChE with IC 50 s of 350 nM and 460 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1334106-34-1. Pack Sizes: 5 mg. Product ID: HY-121072. | |
| AST 487 | AST 487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NVP-AST 487. CAS No. 630124-46-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15002. | |
| AST5902 | AST5902 is the active metabolite of Firmonertinib (HY-112870) (EGFR inhibitor). AST5902 has antineoplastic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2412155-74-7. Pack Sizes: 1 mg. Product ID: HY-138627. | |
| Astaxanthin | Astaxanthin, the red dietary carotenoid, is an orally effective and potent antioxidant. Astaxanthin inhibits NF-κB and down-regulates VEGF in blood glucose. Astaxanthin exerts anti-cancer cell proliferation, increases apoptosis , impairs migration and invasion by activating PPARγ and reducing the expression of STAT3. Astaxanthin also has neuroprotective and anti-inflammatory activity and can be used in studies of cancer, diabetic retinopathy, cardiovascular disease, and in the coloring of animal feed [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 472-61-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2163. | |
| Astegolimab | Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting ST2 , the IL-33 receptor. Astegolimab has the potential for chronic obstructive pulmonary disease (COPD) research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MSTT 1041A; RG 6149. CAS No. 2173054-79-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99444. | |
| Astemizole | Astemizole (R 43512), a second-generation antihistamine agent to diminish allergic symptoms with a long duration of action, is a histamine H1-receptor antagonist, with an IC 50 of 4 nM. Astemizole also shows potent hERG K + channel blocking activity with an IC 50 of 0.9 nM. Astemizole has antipruritic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 43512. CAS No. 68844-77-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12532. | |
| Astilbin | Astilbin is a flavonoid compound and enhances NRF2 activation. Astilbin also suppresses TNF-α expression and NF-κB activation. Uses: Scientific research. Group: Natural products. CAS No. 29838-67-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0509. | |
| Astragalin | Astragalin (Astragaline) a flavonoid with anti-inflammatory, antioxidant, anticancer, bacteriostatic activity. Astragalin inhibits cancer cells proliferation and migration, induces apoptosis. Astragalin is orally active and provides nerve and heart protection, and resistance against and osteoporosis[1]. Uses: Scientific research. Group: Natural products. Alternative Names: Astragaline; 3-Glucosylkaempferol; Kaempferol 3-?-D-glucopyranoside. CAS No. 480-10-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0015. | |
| Astragaloside IV | Astragaloside IV, an active component isolated from Astragalus membranaceus , suppresses the activation of ERK1/2 and JNK , and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells. Uses: Scientific research. Group: Natural products. CAS No. 84687-43-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0431. | |
| Astressin | Astressin is a potent corticotropin releasing factor ( CRF ) antagonist. Uses: Scientific research. Group: Peptides. CAS No. 170809-51-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0257. | |
| Astrophloxine | Astrophloxine is a fluorescent imaging probe capable of targeting antiparallel dimers. Astrophloxine can be used to detect aggregated Aβ in brain tissue and cerebrospinal fluid samples of Alzheimer's disease (AD) mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 14696-39-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-112636. | |
| ASTX029 | ASTX029 (Example 1) is a potent dual ERK1/2 inhibitor ( IC 50 : 2.7 nM). ASTX029 has anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095719-92-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126288. | |
| Asukamycin | Asukamycin, a manumycin-type metabolite, could be isolated from Streptomyces nodosus subsp. asukaensis. Asukamycin is an antibiotic and has antimicrobial activity. Asukamycin inhibits growth of various tumor cell lines [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 61116-33-4. Pack Sizes: 500 μg. Product ID: HY-118893. | |
| Asunaprevir | Asunaprevir (BMS-650032) is a potent and orally bioavailable hepatitis C virus (HCV) NS3 protease inhibitor, with IC 50 of 0.2 nM-3.5 nM [1]. Asunaprevir inhibits SARS-CoV-2 3CL pro activity [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-650032. CAS No. 630420-16-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14434. | |
| Asundexian | Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC 50 of 1 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-2433334. CAS No. 2064121-65-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137431. | |
| Asunercept | Asunercept (APG101; CAN008) is a soluble CD95-Fc fusion protein targeting CD95L. Asunercept disrupts CD95/CD95L signaling by selectively binding to CD95L. Asunercept can be used in the research of glioblastoma multiforme (GBM), myelodysplastic syndrome (MDS), and graft-versus-host disease (GvHD) [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: APG101; CAN008. CAS No. 1450882-18-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99445. | |
| Asymmetric dimethylarginine | Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS) , and functions as a marker of endothelial dysfunction in a number of pathological states. Uses: Scientific research. Group: Natural products. Alternative Names: NG,NG-Dimethylarginine. CAS No. 30315-93-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-113216. | |
| AT 1001 | AT 1001 is a high-affinity and selective antagonist of the α3β4 nicotinic acetylcholine receptor ( α3β4 nAChR ) ( K i =2.64 nM). AT 1001 reversibly blocks inward currents induced by Epibatidine (HY-101078) in HEK cells transfected with α3β4 nAChR. AT-1001 dose-dependently inhibits nicotine self-administration behavior in rats without affecting food-reinforced responding. AT 1001 can be utilized in the research of nicotine addiction and smoking cessation therapies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1314801-63-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135783. | |
| AT-121 | AT-121 is a bifunctional nociception and mu opioid receptor agonist, with K i s of 3.67 and 16.49 nM, respectively. AT-121 is a safe, non-addictive analgesic, and shows antinociceptive and antiallodynic effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2099681-31-7. Pack Sizes: 100 μg (2.16 mM * 100 μL in Chloroform). Product ID: HY-112692. | |
| AT-130 | AT-130, a phenylpropenamide derivative, is a potent hepatitis B virus (HBV) replication non-nucleoside inhibitor. AT-130 inhibits the viral DNA synthesis with an EC 50 of 0.13 μM. AT-130 inhibits both wt and mutant HBVs. AT-130 has anti-HBV activity in hepatoma cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 211364-06-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100028. | |
| AT13148 | AT13148 is an orally active and ATP-competitive, multi- AGC kinase inhibitor with IC 50 s of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1056901-62-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16071. | |
| AT6 | AT6 is a PROTAC AT1 analogue, which is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 with highly selectivity to bromodomain (Brd4). Uses: Scientific research. Group: Signaling pathways. CAS No. 2098836-50-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-112375. | |
| AT7519 | AT7519 (AT7519M) as a potent inhibitor of CDKs , with IC 50 s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT7519M. CAS No. 844442-38-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50940. | |
| AT7519 Hydrochloride | AT7519 Hydrochloride is a potent inhibitor of CDKs , with IC 50 s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 902135-91-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50943. | |
| AT7519 TFA | AT7519 (AT7519M) TFA as a potent inhibitor of CDKs , with IC 50 s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT7519M TFA. CAS No. 1431697-85-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50940A. | |
| AT7867 | AT7867 is a potent ATP-competitive inhibitor of Akt1 / Akt2 / Akt3 and p70S6K / PKA with IC 50 s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 857531-00-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12059. | |
| AT7867 dihydrochloride | AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1 / Akt2 / Akt3 and p70S6K / PKA with IC 50 s of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1431697-86-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12059A. | |
| AT791 | AT791 is a potent and orally bioavailable TLR7 and TLR9 inhibitor. AT791 inhibits TLR7 and 9 signaling in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1219962-49-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-124603. | |
| AT9283 | AT9283 is a multi-targeted kinase inhibitor with potent activity against Aurora A/B , JAK2/3 , Abl (T315I) and Flt3 ( IC 50 s ranging from 1 to 30 nM). AT9283 inhibits growth and survival of multiple solid tumors in vitro and in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 896466-04-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50514. | |
| Atabecestat | Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction. Atabecestat s tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat has the potential for Alzheimer's Disease treatment [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-54861911. CAS No. 1200493-78-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-109052. | |
| Atacicept | Atacicept (TACI-Ig) is a is a recombinant fusion protein containing the extracellular, ligand-binding portion of the TACI receptor and the Fc portion of human IgG. Atacicept inhibits B cell stimulation by binding to B lymphocyte stimulator and a proliferation-inducing ligand. Atacicept can be used in research of B-cell autoimmune disease [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TACI-Ig; TACI-Fc 5. CAS No. 845264-92-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99446. | |
| Ataciguat | Ataciguat (HMR-1766) is a nitric oxide-independent soluble guanylate cyclase (sGC) activator. Ataciguat is able to activate the ferric heme-iron redox form of sGC that stimulate the production of cyclic GMP (cGMP). Ataciguat exhibits vasodilator effects[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HMR-1766. CAS No. 254877-67-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17500. | |
| Ataluren | Ataluren (PTC124) is an orally available CFTR-G542X nonsense allele inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTC124. CAS No. 775304-57-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14832. | |
| Atazanavir | Atazanavir (BMS-232632) is a highly selective and orally active HIV-1 protease inhibitor. Atazanavir is a substrate and inhibitor of CYP3A4 , and an inhibitor of P-glycoprotein (P-gp). Atazanavir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 3.49 μM. Atazanavir inhibits cardiac fibrosis, hyperlipidemia and induces malignant glioma death [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. Alternative Names: BMS-232632. CAS No. 198904-31-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17367. | |
| Atazanavir sulfate | Atazanavir (BMS-232632) sulfate is a highly selective and orally active HIV-1 protease inhibitor. Atazanavir sulfate is a substrate and inhibitor of CYP3A4 , and an inhibitor of P-glycoprotein (P-gp). Atazanavir sulfate is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 3.49 μM. Atazanavir sulfate inhibits cardiac fibrosis, hyperlipidemia and induces malignant glioma death [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. Alternative Names: BMS-232632 sulfate. CAS No. 229975-97-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17367A. | |
| ATC0175 | ATC0175 is a potent, selective and orally active melanin-concentrating hormone 1 recepter antagonist with IC 50 s of 13.5, >10000 nM for MCH1R, MCH2R, respectively. ATC0175 shows antidepressant effects and anxiolytic effects in animal models. ATC0175 has the potential for the research of depression and/or anxiety disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 510733-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107624. | |
| Atenolol | Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a K i of 697 nM at β1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (RS)-Atenolol. CAS No. 29122-68-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-17498. | |
| Atenolol-d7 | Atenolol-d 7 is the deuterium labeled Atenolol. Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a Ki of 697 nM atβ1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (RS)-Atenolol-d7. CAS No. 1202864-50-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-17498S. | |
| Atenolol (Standard) | Atenolol (Standard) is the analytical standard of Atenolol. This product is intended for research and analytical applications. Atenolol ((RS)-Atenolol) is a cardioselective β1-adrenergic receptor blocker, with a K i of 697 nM atβ1-adrenoceptor in guine pig left ventricle membrane. Atenolol can be used for the research of hypertension and angina pectoris [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (RS)-Atenolol (Standard). CAS No. 29122-68-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17498R. | |
| Atevirdine | Atevirdine is a potent non-nucleoside HIV-1 reverse transcriptase inhibitor. Atevirdine inhibits non-nucleoside reverse transcriptase that leads to viral multiplication [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 136816-75-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-15379. | |
| Atezolizumab | Atezolizumab (MPDL3280A) is a selective humanized monoclonal IgG1 antibody against programmed death ligand 1 ( PD-L1 ), used for cancer research. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MPDL3280A. CAS No. 1380723-44-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9904. | |
| ATF3 inducer 1 | ATF3 inducer 1 is a potent ATF3 inducer. ATF3 inducer 1 increases the ATF3 protein and ATF3 mRNA expression. ATF3 inducer 1 shows anti-MetS activity in mouse[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3038756-30-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151923. | |
| ATF4-IN-1 | ATF4-IN-1 (Compound 21) is an ATF4 inhibitor and also an eIF2B activator. ATF4-IN-1 can be used in research on neurodegenerative diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2991057-76-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-158201. | |
| ATG-031 | ATG-031 is a humanized anti-CD24 monoclonal antibody with high affinity and specificity. ATG-031 interacts with Siglec-10 expressed by tumor-associated macrophages. ATG-031 effectively stimulates macrophage-mediated phagocytosis and induces cancer cell destruction by blocking the anti-phagocytic surface proteins. ATG-031 can be used in the study of haematological malignancies as well as solid tumors. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003)[1][2][3]. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99176. | |
| ATG7-IN-1 | ATG7-IN-1 (Compound 37) is a potent and selective inhibitor of ATG7 (IC50 = 62 nM). Uses: Scientific research. Group: Signaling pathways. CAS No. 2226229-87-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145371. | |
| Atglistatin | Atglistatin is a selective adipose triglyceride lipase (ATGL) inhibitor which inhibits lipolysis with an IC50 of 0.7 ?M in vitro. Uses: Scientific research. Group: Signaling pathways. CAS No. 1469924-27-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15859. | |
| Aticaprant | Aticaprant (CERC-501) is a potent and centrally-penetrant kappa opioid receptor antagonist with a K i of 0.807 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CERC-501; LY-2456302. CAS No. 1174130-61-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101718. | |
| ATIC-IN-1 acetate | ATIC-IN-1 (compound 14) acetate is an inhibitor targeting to Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM, whcich catalyzes de novo purine biosynthesis. ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. ATIC-IN-1 acetate exhibits anti-tumor activity via reduction in cell numbers and cell division rates[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150252A. | |
| Atipamezole | Atipamezole (MPV 1248) is a potent α 2 -adrenoceptor antagonist with a K i of 1.6 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MPV 1248. CAS No. 104054-27-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12380A. | |
| Atipamezole hydrochloride | Atipamezole (MPV-1248) hydrochloride is a potent α 2 -adrenoceptor antagonist with a K i of 1.6 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MPV-1248 hydrochloride. CAS No. 104075-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12380. | |
| Atizoram | Atizoram (CP-80,633), a cyclic nucleotide phosphodiesterase (PDE4) inhibitor, elevates plasma cyclic AMP levels and decreases tumor necrosis factor-α (TNFα) production in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-80,633. CAS No. 135637-46-6. Pack Sizes: 500 μg. Product ID: HY-108623. | |
| ATN-224 | ATN-224 is an oral Cu 2+ /Zn 2+ -superoxide dismutase 1 ( SOD1 ) inhibitor. ATN-224 inhibits SOD1 activity in endothelial cells, an effect that is dose dependent with an IC 50 of 17.5±3.7 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bis(choline)tetrathiomolybdate. CAS No. 649749-10-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16074. | |
| Atogepant | Atogepant (MK-8031) is an orally active and selective calcitonin gene - related peptide receptor (CGRP) antagonist. Atogepant can be used for researching migraine [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-8031; AGN-241689. CAS No. 1374248-81-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109022. | |
| Atoltivimab | Atoltivimab (REGN3470), or maftivimab/odesivimab (Inmazeb) is the first Food and agent Administration (FDA)-approved monoclonal antibody to target Zaire ebolaviru s ( EBOV s) infection [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN3470. CAS No. 2135632-29-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99343. | |
| Atomoxetine hydrochloride | Atomoxetine (Tomoxetine) hydrochloride is a selective noradrenaline reuptake inhibitor with K i values of 5 nM, 77 nM and 1451 nM for norepinephrine (NE), serotonin (5-HT) and dopamine (DA) transporters, respectively. Atomoxetine hydrochloride is a potent Na + channels (VGSCs) blocker. Atomoxetine hydrochloride can be used for attention-deficit hyperactivity disorder (ADHD) research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tomoxetine hydrochloride; (R)-Tomoxetine hydrochloride; LY 139603. CAS No. 82248-59-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-17385. | |
| Atopaxar | Atopaxar (E5555) is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist. Atopaxar, an antiplatelet agent, interferes with platelet signaling. Atopaxar can be used for the research of atherothrombotic disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E5555; ER-172594-00. CAS No. 751475-53-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-18200. | |
| Atorvastatin | Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation and invasion with IC 50 s of 0.39 μM and 2.39 μM, respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 134523-00-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-B0589. | |
| Atorvastatin calcium hydrate | Atorvastatin calcium salt trihydrate is a drug belonging to the statin class of drugs used to lower blood cholesterol levels. Atorvastatin calcium salt trihydrate has unique chemical properties that make it an effective tool in controlling high levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the body, reducing the risk of heart attack and stroke. Atorvastatin calcium salt trihydrate works by inhibiting HMG-CoA reductase, the enzyme responsible for producing cholesterol in the liver. Uses: Scientific research. Group: Natural products. CAS No. 344423-98-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-112490. | |
| Atorvastatin hemicalcium salt | Atorvastatin hemicalcium salt (CI-981) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin hemicalcium salt inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 ?M and 2.39 ?M, respectively[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI-981; Atorvastatin hemicalcium. CAS No. 134523-03-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-17379. | |
| Atorvastatin hemicalcium trihydrate | Atorvastatin hemicalcium trihydrate is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin hemicalcium trihydrate inhibits human SV-SMC proliferation and invasion with IC 50 s of 0.39 μM and 2.39 μM, respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 344920-08-7. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0589E. | |
| Atosiban | Atosiban (RW22164; RWJ22164) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research [1]. Uses: Scientific research. Group: Peptides. Alternative Names: RW22164; RWJ22164. CAS No. 90779-69-4. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-17572. | |
| Atosiban acetate | Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research [1]. Uses: Scientific research. Group: Peptides. Alternative Names: RW22164 acetate; RWJ22164 acetate. CAS No. 914453-95-5. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-17572A. | |
| Atovaquone | Atovaquone (Atavaquone) is a potent, selective and orally active inhibitor of the parasites mitochondrial cytochrome bc1 complex. Atovaquone is against human and P. falciparum cytochrome bc1 activity with IC 50 values of 460 nM and 2.0 nM, respectively. Atovaquone is an antimalarial agent and has the potential for the investigation of neumocystis pneumonia, toxoplasmosis, malaria, and babesia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Atavaquone. CAS No. 95233-18-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13832. | |
| ATP | ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Adenosine 5'-triphosphate. CAS No. 56-65-5. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B2176. | |
| ATPA | ATPA is a selective glutamate receptor GluR5 activator with EC 50 s of 0.66, 9.5, 1.4, 23, 32, 18, and 14 μM for GluR5wt, GluR5(S741M), GluR5(S721T), GluR5(S721T, S741M), GluR5(S741A), GluR5(S741L), and GluR5(S741V), respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 140158-50-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-101261. | |
| ATPase-IN-3 | ATPase-IN-3 (compound 6) is a ATPase inhibitor. ATPase-IN-3 has Gastroprotective effect in ethanol-induced gastric ulcers by contribution of anti-apoptotic ( BCL-2 ) and tumor suppressor ( P53 ) proteins [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1134203-12-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161254. | |
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