MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| AZD 2066 | AZD-2066 is a selective, orally active and blood-brain barrier-permeating mGluR5 antagonist. AZD 2066 activates the BDNF/trkB signaling pathway. AZD 2066 can be used in the research of neuropathic pain, major depressive disorder and gastroesophageal reflux disease [1] [2] [3] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 934282-55-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-110255. |  |
| AZD2098 | AZD2098 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 566203-88-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00064. | |
| AZD2858 | AZD2858 is a potent, orally active GSK-3 inhibitor, with IC50s of 0.9 and 5 nM for GSK-3? and GSK-3?, respectively, used in the research of fracture healing. Uses: Scientific research. Group: Signaling pathways. CAS No. 486424-20-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15761. | |
| AZD3229 | AZD3229 is a potent pan- KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. AZD3229 inhibits c-KIT with an IC 50 value of 223.3 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2248003-60-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112802. | |
| AZD3229 Tosylate | AZD3229 Tosylate is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. Uses: Scientific research. Group: Signaling pathways. CAS No. 2248003-71-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112802A. | |
| AZD3458 | AZD3458 is a potent and remarkably selective PI3K? inhibitor with pIC50s of 9.1, 5.1, <4.5, and 6.5 for PI3K?, PI3K?, PI3K?, and PI3K?, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2132961-46-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112443. | |
| AZD-3463 | AZD-3463 (ALK/IGF1R inhibitor) is an orally active ALK/IGF1R inhibitor, with a Ki of 0.75 nM for ALK. AZD3463 induces apoptosis and autophagy in neuroblastoma cells[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALK/IGF1R inhibitor. CAS No. 1356962-20-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15609. | |
| AZD3514 | AZD3514 is an orally activie and selective androgen receptor (AR) inhibitor. AZD3514 androgen-dependently and -independently inhibits AR signal. AZD351 down-regulates nuclear AR levels in human LNCaP prostate cancer cells in the absence of androgen with an pIC50 value of 5.75. AZD3514 can be used for the research of prostate cancer[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1240299-33-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16079. | |
| AZD3839 free base | AZD3839 free base is a potent and selective orally active, brain-permeable BACE1 inhibitor ( K i=26 nM). AZD3839 free base shows 14 and >1000-fold selectivity against BACE2 and cathepsin D, respectively. AZD3839 free base exhibits dose- and time-dependent lowering of plasma, brain, and cerebrospinal fluid Aβ levels in mouse, guinea pig, and non-human primate. AZD3839 free base can be used for the research of Alzheimer's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1227163-84-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-13438. | |
| AZD3965 | AZD3965 is a selective MCT1 inhibitor with a K i of 1.6 nM, showing 6-fold selectivity over MCT2. Uses: Scientific research. Group: Signaling pathways. CAS No. 1448671-31-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12750. | |
| AZD4144 | AZD4144 is an orally active NLRP3 inhibitor (EC50: 0.082 ?M). AZD4144 effectively inhibits the release of IL-1? when NLRP3 is overactivated, exerting an anti-inflammatory effect. AZD4144 has low inhibitory effect on hERG and low cardiotoxicity. AZD4144 has the potential to study diseases and conditions associated with NLRP3 inflammasome activation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2890191-41-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162877. | |
| AZD4320 | AZD4320 is a novel BH3-mimicking dual BCL2/BCLxL inhibitor with IC 50 s of 26 nM, 17 nM, and 170 nM for KPUM-MS3, KPUM-UH1, and STR-428 cells, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1357576-48-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112416. | |
| AZD4573 | AZD4573 is a potent and highly selective CDK9 inhibitor ( IC 50 of <4 nM) that enables transient target engagement for the treatment of hematologic malignancies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2057509-72-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112088. | |
| AZD4694 Precursor | AZD4694 Precursor (AZ13040214) is the precursor of [ 18 F] AZD4694 for the synthesis of [ 18 F] AZD4694, an amyloid-β imaging ligand with high affinity for amyloid-β plaques [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZ13040214; NAV4614. CAS No. 1211333-20-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139516. | |
| AZD-5069 | AZD-5069 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment. Uses: Scientific research. Group: Signaling pathways. CAS No. 878385-84-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19855. | |
| AZD5153 | AZD5153 (Compound 13) is a trivalent triazolpyrazine bromide domain (BRD), bromodomain and extraterminal (BET) inhibitor. AZD5153 has down-regulated c-Myc gene and tumor growth inhibition activity. AZD5153 can be used in the study of BET small molecule inhibitors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1869912-39-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-100653. | |
| AZD5153 6-Hydroxy-2-naphthoic acid | AZD5153 6-Hydroxy-2-naphthoic acid is the 6-Hydroxy-2-naphthoic acid of AZD5153. AZD5153 is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor; disrupts BRD4 with an IC 50 of 1.7 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1869912-40-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100653A. | |
| AZD5423 | AZD5423 is an inhaled, potent, selective, and non-steroidal glucocorticoid receptor (GR) modulator (SGRM) [1]. AZD5423 effectively reduces allergen-induced responses in subjects with mild allergic asthma [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1034148-04-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108243. | |
| AZD-5438 | AZD-5438 is a potent CDK1, CDK2, and CDK9 inhibitor, with IC50s of 16 nM, 6 nM, and 20 nM in cell-free assays, respectively. AZD-5438 shows less inhibition activity against GSK3?, CDK5 and CDK6[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 602306-29-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10012. | |
| AZD5582 | AZD5582 is an antagonist of the inhibitor of apoptosis proteins (IAPs), which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. AZD5582 induces apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1258392-53-8. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-12600. | |
| AZD5904 | AZD5904 is a selective and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has similar potency in mouse and rat. Uses: Scientific research. Group: Signaling pathways. CAS No. 618913-30-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111341. | |
| AZD-5991 | AZD-5991 is a potent and selective Mcl-1 inhibitor with an IC50 of 0.7 nM in FRET assay and a Kd of 0.17 nM in surface plasmon resonance (SPR) assay[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2143061-81-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101533. | |
| AZD 6482 | AZD 6482 (KIN-193) is a potent and selective p110? inhibitor with an IC50 of 0.69 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KIN-193. CAS No. 1173900-33-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10344. | |
| AZD7325 | AZD7325 is a potent and orally active partial selective PAM of GABAAα2 and Aα3 receptor ( K i =0.3 and 1.3 nM, respectively), and has less antagonistic efficacy at the Aα1 and Aα5 receptor subtypes [1] [4]. AZD7325 is a moderate CYP1A2 and a potent CYP3A4 inducer in vitro [2]. AZD7325 has the potential for the investigation of anxiety and dravet syndrome [3]. PAM: positive allosteric modulator. Uses: Scientific research. Group: Signaling pathways. CAS No. 942437-37-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111052. | |
| AZD7545 | AZD7545 is a potent, competitive, selective PDHK2 (pyruvate dehydrogenase kinase 2) inhibitor with IC50s of 36.8 nM, 6.4 nM for PDHK1 and PDHK2, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 252017-04-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16082. | |
| AZD-7648 | AZD-7648 is a potent, orally active, selective DNA-PK inhibitor with an IC50 of 0.6 nM. AZD-7648 induces apoptosis and shows antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230820-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-111783. | |
| AZD-7762 | AZD-7762 is a potent ATP-competitive checkpoint kinase (Chk) inhibitor in with an IC50 of 5 nM for Chk1. Uses: Scientific research. Group: Signaling pathways. CAS No. 860352-01-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10992. | |
| AZD-8055 | AZD-8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC 50 of 0.8 nM. AZD-8055 inhibits both mTORC1 and mTORC2 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1009298-09-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10422. | |
| AZD8186 | AZD8186 is a PI3K inhibitor, which potently inhibits PI3Kβ (IC 50 =4 nM) and PI3Kδ (IC50 50 =12 nM) with selectivity over PI3Kα (IC 50 =35 nM) and PI3Kγ (IC 50 =675 nM). Uses: Scientific research. Group: Signaling pathways. CAS No. 1627494-13-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12330. | |
| AZD8330 | AZD8330 (ARRY-424704) is a potent, uncompetitive MEK1/MEK2 inhibitor, with an IC50 of 7 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARRY-424704; ARRY-704. CAS No. 869357-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12058. | |
| AZD8421 | AZD8421 is a selective CDK2 inhibitor (IC50 = 9 nM) as well as achieving CDK family selectivity in cells versus key off-targets (CDK1, CDK4/6, CDK9), AZD8421 had no significant kinase inhibition outside the CDK family. AZD8421 inhibits cancer cell proliferation by inhibiting pRB phosphorylation, inducing cell cycle arrest in G1/S phase and senescence. AZD8421 can be studied in research for breast cancer and ovarian cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3047321-53-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-158106. | |
| AZD-8529 | AZD-8529 is a potent, highly selective and orally bioavailable positive allosteric modulator of mGluR2 , with an EC 50 of 285 nM, and shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092453-15-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107457. | |
| AZD-8529 mesylate | AZD-8529 mesylate is a potent, highly selective and orally bioavailable positive allosteric modulator of mGluR2 , with an EC 50 of 285 nM, and shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1314217-69-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107457A. | |
| AZD9056 hydrochloride | AZD9056 hydrochloride is a selective orally active inhibitor of P2X7 which plays a significant role in inflammation and pain-causing diseases. Uses: Scientific research. Group: Signaling pathways. CAS No. 345303-91-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19427A. | |
| AZD9496 | AZD9496 is an effective, selective estrogen receptor ( ERα ) antagonist with an IC 50 of 0.28 nM. AZD9496 is an orally active, selective estrogen receptor degrader (SERD). Uses: Scientific research. Group: Signaling pathways. CAS No. 1639042-08-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12870. | |
| AZD9496 maleate | AZD9496 maleate is a potent and selective estrogen receptor ( ERα ) antagonist with IC 50 of 0.28 nM. AZD9496 maleate is an orally bioavailable selective oestrogen receptor degrader (SERD). Uses: Scientific research. Group: Signaling pathways. CAS No. 1639042-28-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12870A. | |
| AzddMeC | AzddMeC (CS-92) is an antiviral nucleoside analogue and a potent potent, selective and orally active HIV-1 reverse transcriptase and HIV-1 replication inhibitor. In HIV-1 -infected human PBM cells and HIV-1 -infected human macrophages, the EC 50 values of AzddMeC are 9 nM and 6 nM, respectively [1] [2]. AzddMeC is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CS-92. CAS No. 87190-79-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105268. | |
| Azelaic acid | Azelaic acid is a nine-carbon dicarboxylic acid. Azelaic acid has antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis through inhibition of microbial cellular prorein synthesis. Azelaic acid has hypopigmentation action resulting from its ability to scavenge free radicals [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Nonanedioic acid. CAS No. 123-99-9. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-B0704. | |
| Azelaprag | Azelaprag (Example 263.0) is a candidate active molecule for an Apelin receptor agonist with an EC50 of 0.32 nM for the apelin receptor[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMG 986. CAS No. 2049980-18-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109111. | |
| Azelastine hydrochloride | Azelastine hydrochloridem, an antihistamine, is a potent and selective histamine 1 (H 1 ) antagonist. Azelastine hydrochloride can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2 [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79307-93-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-B0462. | |
| Azeliragon | Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression in patients with mild Alzheimers disease (AD)[1]. Azeliragon also can cross the blood-brain barrier (BBB)[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TTP488; PF-04494700. CAS No. 603148-36-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50682. | |
| Azelnidipine | Azelnidipine (CS 905) is a dihydropyridine calcium channel blocker that is effective orally. Azelnidipine inhibits the intracellular calcium ion flow and lower blood pressure by selectively blocking L-type calcium channel on the membrane of vascular smooth muscle. Azelnidipine inhibits esophageal squamous cell carcinoma proliferation by targeting MEK1/2. Azelnidipine also has anti-inflammatory, antioxidant and neuroprotective effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CS 905. CAS No. 123524-52-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0023. | |
| Azemiglitazone | Azemiglitazone (MSDC-0602) is an orally active thiazolidinedione (TZD) -like molecule, which binds to PPARγ with low binding and activating affinity. Azemiglitazone inhibits mitochondrial pyruvate carrier ( MPC ), which inhibits Alzheimers disease and diminishes nonalcoholic steatohepatitis (NASH) caused liver injury [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MSDC-0602. CAS No. 1133819-87-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108022. | |
| Azemiglitazone potassium | Azemiglitazone potassium (MSDC-0602K), a PPARγ -sparing thiazolidinedione (Ps-TZD), binds to PPARγ with the IC 50 of 18.25 μM [1]. Azemiglitazone potassium modulates the mitochondrial pyruvate carrier (MPC). Azemiglitazone potassium can be used for the research of fatty liver including dysfunctional lipid metabolism, inflammation, and insulin resistance [2]. Azemiglitazone potassium, an insulin sensitizer, improves insulinemia and fatty liver disease in mice, alone and in combination with Liraglutide [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MSDC-0602K. CAS No. 1314533-27-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108022A. | |
| Azenosertib | Azenosertib (ZN-c3) is a selective, orally active inhibitor for Wee1 inhibitor ( IC 50 =3.9 nM). Azenosertib exhibits antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZN-c3. CAS No. 2376146-48-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132295. | |
| Azepan-2-one | Azepan-2-one is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 105-60-2. Pack Sizes: 25 g; 50 g. Product ID: HY-W010542. | |
| Azetidine-2-carboxylic acid | Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline. Found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. Toxic and teratogenic agent [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 2517-4-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-75308. | |
| Azetidine-3-carboxylic acid | Azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2. Uses: Scientific research. Group: Signaling pathways. CAS No. 36476-78-5. Pack Sizes: 10 g; 25 g. Product ID: HY-Y0530. | |
| Azetidine hydrochloride | Azetidine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Trimethyleneimine hydrochloride. CAS No. 36520-39-5. Pack Sizes: 5 g; 10 g. Product ID: HY-W010628. | |
| Azetukalner | KCNQ2/3 activator-1 is an activator of Kv7.2/Kv7.3 ( KCNQ2/3 ) potassium channel. KCNQ2/3 activator-1 has the potential in relieving pain (the main problem from medical treatment) (extracted from patent WO2021113757A1, compound A) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XEN1101. CAS No. 1009344-33-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-139791. | |
| Azide-PEG4-VC-PAB-Doxorubicin | Azide-PEG4-VC-PAB-Doxorubicin is a agent-linker conjugate composed of a cytotoxic anthracycline antibiotic Doxorubicin and a linker Azide-PEG4-VC-PAB to make antibody agent conjugate (ADC)[1]. Azide-PEG4-VC-PAB-Doxorubicin is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136288. | |
| Azidoacetic Acid | Azidoacetic Acid (2-Azidoacetic acid) (compound 92-1) is a click chemistry reagent containing an azide group. Azidoacetic Acid can be used as a small molecule tool for the synthesis of PROTAC [1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Azidoacetic acid. CAS No. 18523-48-3. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-151719. | |
| Azido-PEG1 | Azido-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1517-05-1. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-138461. | |
| Azido-PEG10-NHS ester | Azido-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG10-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2801772-86-9. Pack Sizes: 100 mg. Product ID: HY-140759. | |
| Azido-PEG1-CH2CO2H | Azido-PEG1-CH2CO2H is a PROTAC linker, which refers to the alkyl/ether composition. Azido-PEG1-CH2CO2H can be used in the synthesis of PROTAC BRD4 Degrader-1[1]. Azido-PEG1-CH2CO2H is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 79598-48-4. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-108369. | |
| Azido-PEG2-alcohol | Azido-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG2-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 139115-90-5. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-140797. | |
| Azido-PEG2-C2-acid | Azido-PEG2-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG2-C2-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1312309-63-9. Pack Sizes: 250 mg; 500 mg; 1 g. Product ID: HY-140452. | |
| Azido-PEG2-C2-amine | Azido-PEG2-C2-amine (N3-PEG2-CH2CH2NH2) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG2-C2-amine is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. Azido-PEG2-C2-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N3-PEG2-CH2CH2NH2. CAS No. 166388-57-4. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-140213. | |
| Azido-PEG3-Val-Cit-PAB-PNP | Azido-PEG3-Val-Cit-PAB-PNP is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG3-Val-Cit-PAB-PNP is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG3-Val-Cit-PAB-PNP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2055047-18-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140150. | |
| Azido-PEG4-NHS-ester | Azido-PEG4-NHS-ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Azido-PEG4-NHS-ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1807534-82-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-140765. | |
| Azido-PEG5-alcohol | Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG5-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 86770-68-5. Pack Sizes: 250 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-130211. | |
| Azido-PEG5-amine | Azido-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG5-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 516493-93-9. Pack Sizes: 100 mg; 250 mg. Product ID: HY-140214. | |
| Azido-PEG5-NHS ester | Azido-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1433996-86-1. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-140757. | |
| Azido-PEG6-acid | Azido-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 361189-66-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-140453. | |
| Azilsartan | Azilsartan (TAK-536) is an orally active, potent, selective and specific angiotensin II type 1 receptor (AT1) antagonist. Azilsartan induces ROS formation and apoptosis in HepG2 cells. Azilsartan shows neuroprotective and anticancer activity. Azilsartan can be used for hypertension and stroke research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-536. CAS No. 147403-03-0. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-14914. | |
| Azilsartan medoxomil | Azilsartan medoxomil (TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC 50 of 0.62 nM, which used in the treatment of adults with essential hypertension [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-491. CAS No. 863031-21-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14736. | |
| Azimilide | Azimilide(NE-10064) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NE-10064. CAS No. 149908-53-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-18600. | |
| Azimilide dihydrochloride | Azimilide (NE-10064) dihydrochloride is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NE-10064 dihydrochloride. CAS No. 149888-94-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-18600A. | |
| Azimsulfuron | Azimsulfuron (DPX-A8947) is a sulfonylurea herbicide useful in controlling weeds in paddy fields [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DPX-A8947. CAS No. 120162-55-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121079. | |
| Azintuxizumab | Azintuxizumab is an anti- SLAMF7 human IgG4κ monoclonal antibody. Azintuxizumab can be used in the synthesis of antibody-drug conjugate (ADC), Azintuxizumab vedotin [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1826819-57-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99453. | |
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