MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| β-Ocimene | Beta-Ocimene is a naturally occurring organic compound that belongs to the terpene family. It exists as a mixture of three isomers: cis β-Ocimene, trans β-Ocimene and myrcene-like β-Ocimene. It has a pleasant, sweet herbaceous scent and is found in many plants, including mint, basil, parsley, and kumquat. β-Ocimene is widely used in the flavor and fragrance industry due to its characteristic aroma and taste. It also has potential applications in agriculture as natural insect repellants and pheromones that attract beneficial insects. β-Ocimene has potential anti-inflammatory and anticancer activities. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 13877-91-3. Pack Sizes: 25 g. Product ID: HY-117215. |  |
| (-)-β-Peltatin | (-)-β-Peltatin is an organic heterotetracyclic compound with antitumor activity and phytometabolite effects that are functionally related to α-peltatin [1]. Uses: Scientific research. Group: Natural products. Alternative Names: β-Peltatin. CAS No. 518-29-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-125135. | |
| β-Phellandrene | β-phellandrene is an orally active monocyclic monoterpenes. β-Phellandrene is obtained from Carum petroselinum. β-phellandrene has strong ability to kill pest. β-phellandrene can be used as oil additives, natural pesticides and synthetic materials [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 555-10-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N8573. | |
| β-Pompilidotoxin | β-Pompilidotoxin (β-PMTX), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells [1]. Uses: Scientific research. Group: Peptides. Alternative Names: β-PMTX. CAS No. 216064-36-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1084. | |
| β-Secretase Inhibitor IV | β-Secretase Inhibitor IV is a potent, cell-active BACE-1 inhibitor with IC 50 s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 797035-11-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-10133. | |
| Beta-Sitosterol (purity>80%) | Beta-Sitosterol (purity>80%) includes β-sitosterol (≥80%), stigmasterol, campesterol and brassicasterol mainly. Beta-Sitosterol is a plant sterol. Beta-Sitosterol (purity>80%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation [1]. Uses: Scientific research. Group: Natural products. CAS No. 83-46-5. Pack Sizes: 100 mg; 1 g; 5 g. Product ID: HY-N0171. | |
| β-Tocopherol | β-Tocopherol is an analogue of vitamin E, exhibits antioxidant properties. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 16698-35-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-133680. | |
| β-Tocotrienol | β-Tocotrienol is one form of vitamin E. β-Tocotrienol is a less potent antioxidant than α-tocotrienol [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 490-23-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108693. | |
| Betaxolol | Betaxolol is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma. Uses: Scientific research. Group: Signaling pathways. CAS No. 63659-18-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0381. | |
| Betaxolol hydrochloride | Betaxolol Hydrochloride is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SL75212. CAS No. 63659-19-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0381A. | |
| Beta-Zearalanol | Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells [1]. Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid [2]. Uses: Scientific research. Group: Natural products. CAS No. 42422-68-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N6740. | |
| β-Zearalenol | β-Zearalenol is a non-steroidal estrogenic mycotoxin synthesized by Fusarium species. β-Zearalenol potentially influences transcription and effects gene expression on translational level [1]. Uses: Scientific research. Group: Natural products. CAS No. 71030-11-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N6741. | |
| BET bromodomain inhibitor | BET bromodomain inhibitor is a potent BET inhibitor extracted from patent WO/2015/153871A2, compound example 11. Uses: Scientific research. Group: Signaling pathways. CAS No. 1505453-59-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103036. | |
| BET bromodomain inhibitor 3 | BET bromodomain inhibitor 3 is BET bromodomain inhibitor. BET bromodomain inhibitor 3 has inhibitory effect against BrdT with K i value of > 40 μM. BET bromodomain inhibitor 3 can be used for the research of contraception, cancer, and heart disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 854137-39-6. Pack Sizes: 10 mg. Product ID: HY-153593. | |
| BET bromodomain inhibitor 4 | BET bromodomain inhibitor 4 (example 7) is an inhibitor of the BET bromodomain domain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2407658-41-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-157393. | |
| Bethanechol chloride | Bethanechol chloride (Carbamyl-β-methylcholine chloride), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Carbamyl-β-methylcholine chloride. CAS No. 590-63-6. Pack Sizes: 10 mM * 1 mL; 200 mg; 5 g. Product ID: HY-B0406A. | |
| BET-IN-14 | BET-IN-14 is an orally active pan BET inhibitor ( IC 50 : 5.35 nM). BET-IN-14 has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2243669-93-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-153226. | |
| Betrixaban | Betrixaban (PRT054021) is a highly potent, selective, and orally efficacious factor Xa (fXa) inhibitor with an IC 50 of 1.5 nM. Betrixaban shows antithrombotic effect [1] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PRT054021. CAS No. 330942-05-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10268. | |
| Betulin | Betulin (Trochol), is a sterol regulatory element-binding protein ( SREBP ) inhibitor with an IC 50 of 14.5 μM in K562 cell line. Uses: Scientific research. Group: Natural products. Alternative Names: Trochol. CAS No. 473-98-3. Pack Sizes: 50 mg; 100 mg; 200 mg. Product ID: HY-N0083. | |
| Betulinic acid | Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC 50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Lupatic acid; Betulic acid. CAS No. 472-15-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-10529. | |
| Bevacizumab | Bevacizumab, a humanized IgG1 monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human VEGF, Humanized Antibody. CAS No. 216974-75-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9906. | |
| Bevantolol hydrochloride | Bevantolol hydrochloride is a selective β1 and α1-adrenergic receptor antagonist with pK i values of 7.83, 6.9 in rat cerebral cortex, respectively. Bevantolol hydrochloride is a potent Ca 2+ antagonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 42864-78-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121186. | |
| Bevenopran | Bevenopran is a peripheral μ-opioid receptor antagonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CB-5945; ADL-5945. CAS No. 676500-67-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100122. | |
| Bevirimat | Bevirimat (PA-457, MPC-4326, YK FH312) is an inhibitor of HIV-1 viral particle maturation.Bevirimat specifically inhibits the final rate-limiting step in Gag processing, preventing the release of the mature capsid protein (CA) from its precursor (CA-SP1), resulting in the production of immature non-infectious viral particles. Bevirimat can be used in HIV-1 infection studies [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: PA-457; MPC-4326; YK FH312. CAS No. 174022-42-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0842. | |
| Bexarotene | Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors ( RXR ) agonist with EC 50 s of 33, 24, 25 nM for RXRα , RXRβ , and RXRγ , respectively. Bexarotene shows limited affinity for RAR receptors (EC 50 >10000 nM) [1] [2] [3]. Bexarotene can be used for the research of cutaneous T-cell lymphoma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LGD1069. CAS No. 153559-49-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-14171. | |
| Bexicaserin | Bexicaserin (LP352) is a 5-HT2C receptor agonist with potential for studying obesity and psychiatric-related disorders (such as epilepsy) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LP352. CAS No. 2035818-24-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156601. | |
| Bexmarilimab | Bexmarilimab (FP-1305) is a potent humanized anti- CLEVER-1 IgG4-antibody with an IC 50 value of 4.51 nM. Bexmarilimab is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: FP-1305. CAS No. 2259301-27-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99236. | |
| Bexotegrast | Bexotegrast (PLN-74809) is an orally active, potent dual αvβ6/αvβ1 integrin inhibitor with K d of 5.7 nM and 3.4 nM, respectively. Bexotegrast inhibits αvβ6- and αvβ1-induced TGF-β activation with IC 50 values of 29.8 nM and 19.2 nM, respectively. Bexotegrast has antifibrogenic effects and block multiple avenues of TGF-β activation in the fibrotic lung [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PLN-74809. CAS No. 2376257-44-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137561. | |
| Bezafibrate | Bezafibrate is an agonist of PPAR , with EC 50 s of 50 μM, 60 μM, 20 μM for human PPARα , PPARγ and PPARδ , and 90 μM, 55 μM, 110 μM for murine PPARα , PPARγ and PPARδ , respectively; Bezafibrate is used as an hypolipidemic agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BM15075. CAS No. 41859-67-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0637. | |
| Bezisterim | Bezisterim (HE 3286; NE-3107) is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. Bezisterim is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. Bezisterim freely penetrates the blood brain barrier in mice. Bezisterim can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis [1] [2] [3]. Bezisterim is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HE 3286; NE-3107. CAS No. 1001100-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108039. | |
| Bezlotoxumab | Bezlotoxumab is a human monoclonal antibody directed against C. difficile toxin B. Bezlotoxumab binds to C. difficile toxin B preventing intestinal epithelial damage and colitis [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1246264-45-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9929. | |
| Bezuclastinib | Bezuclastinib (CGT9486) is an orally active, highly selective tyrosine kinase inhibitor with potent activity against KIT D816V. Bezuclastinib can be used for the research of nonadvanced systemic mastocytosis (NonAdvSM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGT9486; PLX 9486. CAS No. 1616385-51-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145557. | |
| BGC-20-1531 free base | BGC-20-1531 (PGN 1531) free base is a potent and selective prostanoid EP 4 receptor antagonist, with a pK B of 7.6. BGC-20-1531 free base has the potential for the research of migraine headache [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PGN 1531 free base. CAS No. 736183-35-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19849. | |
| BI 224436 | BI 224436 is a novel HIV-1 noncatalytic site integrase inhibitor with EC 50 values of less than 15 nM against different HIV-1 laboratory strains. Uses: Scientific research. Group: Signaling pathways. CAS No. 1155419-89-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18595. | |
| BI-2545 | BI-2545 is a potent autotaxin (ATX) inhibitor that significantly reduces LPA, with IC 50 s of 2.2 nM and 3.4 nM for human ATX and rat ATX, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2162961-71-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124772. | |
| BI-4394 | BI-4394 (MMP13-IN-3) is a potent, selective, and orally active MMP-13 inhibitor ( IC 50=1 nM [1] ) for the potential treatment of osteoarthritis [2]. BI-4394 is >1000 selective over other MMPs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MMP13-IN-3. CAS No. 1222173-37-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124029. | |
| BI 639667 | BI 639667 (compound 19n), a third azaindazole series compound, is a CCR1 antagonist, with an IC 50 of 1.8 nM in Ca 2+ flux assay [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCR1 antagonist 8. CAS No. 1295298-26-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-120588. | |
| BI 99179 | BI 99179 is a potent and selective type I fatty acid synthase ( FAS ) inhibitor with an IC 50 of 79 nM. BI 99179 is a tool compound suitable for the in vivo validation of FAS as a target for lipid metabolism related diseases. BI 99179 exhibits significant exposure (both peripheral and central) upon oral administration in rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1291779-76-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16100. | |
| BIA 10-2474 | BIA 10-2474 is an inhibitor of fatty acid amide hydrolase ( FAAH ) with IC 50 values of 50 to 70mg/kg in various rat brain regions. Uses: Scientific research. Group: Signaling pathways. CAS No. 1233855-46-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19740. | |
| Bialaphos sodium | Bialaphos (SF-1293) sodium, an antibiotic , is an effective herbicide is a metabolite of Streptomyces hygroscopicus [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SF-1293 sodium. CAS No. 71048-99-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-122494A. | |
| Biapenem | Biapenem (CLI 86815; L 627; LJC 10627) a parenteral carbapenem antibacterial agent with a broad spectrum. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CLI 86815; L 627; LJC 10627. CAS No. 120410-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13573. | |
| BIBP3226 TFA | BIBP3226 TFA is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with K i s of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 TFA displays anxiogenic-like effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1068148-47-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107726. | |
| BIBR 1532 | BIBR 1532 is a potent, selective and non-competitive telomerase inhibitor with IC 50 of 100 nM in a cell-free assay. Uses: Scientific research. Group: Signaling pathways. CAS No. 321674-73-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17353. | |
| BIBS 39 | BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 133085-33-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-19732. | |
| Bicalutamide | Bicalutamide is an orally active non-steroidal androgen receptor (AR) antagonist. Bicalutamide can be used for the research of prostate cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 90357-06-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-14249. | |
| Bicarbonate-13C sodium | Bicarbonate- 13 C (sodium) is the 13 C labeled Bicarbonate sodium[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 87081-58-1. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W251598S. | |
| Bicine | Bicine is a buffer used in physiological research. Bicine is a derivative of the simple amino acid glycine that increases the sensitivity of guanosine enzyme histochemical detection [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 150-25-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-D0868. | |
| Bictegravir | Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC 50 of 7.5 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9883. CAS No. 1611493-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17605. | |
| Bictegravir sodium | Bictegravir sodium is a potent inhibitor of HIV-1 integrase , with an IC 50 of 7.5 nM. Bictegravir sodium exhibits potent and selective anti-HIV activity and low cytotoxicity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9883 sodium. CAS No. 1807988-02-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17605A. | |
| Bicuculline | Bicuculline ((+)-Bicuculline) is A competing neurotransmitter GABA A receptor antagonist ( IC 50 =2 μM). Bicuculline also blocks Ca 2+ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP). Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Bicuculline; d-Bicuculline. CAS No. 485-49-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0219. | |
| Bicuculline methiodide | Bicuculline methiodide is a potent GABA(A) receptors blocker. Bicuculline methiodide alters membrane properties and firing pattern. Bicuculline methiodide reduces the Apamin-sensitive afterhyperpolarization, while Apamin is a toxin isolated from bee venom to block small conductance Ca 2+ -activated K + channels. Bicuculline methiodide facilitates burst firing via blocking apamin-sensitive Ca 2+ -activated K + current [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Bicuculline methiodide; l-Bicuculline methiodide. CAS No. 40709-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103474. | |
| (-)-Bicuculline methobromide | (-)-Bicuculline methobromide (l-Bicuculline methobromide) is a potent GABA A receptor antagonist. (-)-Bicuculline methobromide blocks afterhyperpolarizations (AHPs) mediated by Ca 2+ -activated K + channels in various types of neurons [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: l-Bicuculline methobromide. CAS No. 73604-30-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100783. | |
| Bicuculline methochloride | Bicuculline ((+)-Bicuculline; d-Bicuculline) methochloride is a selective GABAA receptor antagonist with an IC 50 value of 3 μM. Bicuculline methochloride induces clonic tonic convulsions in mammals and can also be used to block Ca 2+ activated potassium channels. Bicuculline methochloride can be used in studies of epilepsy and other related psychiatric disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Bicuculline methochloride; l-Bicuculline methochloride. CAS No. 38641-83-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137790. | |
| Bicyclol | Bicyclol (SY801) is an orally active derivative of the traditional Chinese medicine Schisandra chinensis, which has antiviral, anti-inflammatory, immunomodulatory, antioxidant, anti-steatosis, anti-fibrotic and anti-tumor activities. Bicyclol regulates the expression of heat shock proteins and plays an anti- apoptosis role in hepatocytes. Bicyclol reduces the activation of NF-κB and the levels of inflammatory factors in hepatocytes infected with hepatitis C virus (HCV) by inhibiting the activation of the ROS-MAPK-NF-κB pathway, and prevents ferroptosis in acute liver injury. Bicyclol can change the expression of Mdr-1 , GSH/GST and Bcl-2 , increase the intracellular concentration of anticancer drugs, and sensitize drug-resistant cells to anticancer drugs. Bicyclol inhibits the proliferation of human malignant hepatoma cells by regulating the PI3K/AKT pathway and the Ras/Raf/MEK/ERK pathway. Bicyclol can be used in the study of chronic hepatitis, acute liver injury, nonalcoholic fatty liver disease, liver fibrosis and hepatocellular carcinoma [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SY801. CAS No. 118159-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0766. | |
| Bicyclomycin benzoate | Bicyclomycin benzoate is an antibiotic exhibiting activity against a broad spectrum of Gram-negative bacteria and against the Gram-positive bacterium. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FR2054. CAS No. 37134-40-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101128. | |
| Bidisomide | Bidisomide (SC40230) is a class I antiarrhythmic agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC40230. CAS No. 116078-65-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-U00232. | |
| Bifemelane hydrochloride | Bifemelane hydrochloride (MCI-2016) is a potent, selective and competitive inhibitor of monoamine oxidase A (MAO-A) , with a K i of 4.20 μM. Bifemelane hydrochloride also inhibits MAO-B noncompetitively with a K i of 46.0 μM. Bifemelane hydrochloride has a potent antidepressant activity and can be used for the research of cognitive and emotional disturbances related to cerebrovascular disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCI-2016. CAS No. 62232-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1558A. | |
| Bifenazate | Bifenazate is a carbazate acaricide that control 100% of mites at a concentration of 25 ppm [1]. Bifenazate is a positive allosteric modulator of GABA receptor [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 149877-41-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-119687. | |
| Bifendate | Bifendate (DDB), extracted from Schisandrae chinensis , is an orally active anti-HBV agent against chronic hepatitis B. Bifendate inhibits ATG5-dependent autophagy and attenuates oleic acid-induced lipid accumulation with anti-oxidant properties in vitro. Bifendate can decrease alanine transaminase (ALT) level in mice. Bifendate attenuates hepatic steatosis in cholesterol/bile salt- and high-fat diet-induced hypercholesterolemia in mice. Bifendate potently increases the activity of cytochrome proteins ( CYPs ) and reverse P-gp -mediated multi-drug resistance (MDR) [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DDB. CAS No. 73536-69-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W018791. | |
| Bifenthrin | Bifenthrin is a synthetic pyrethroid insecticide. Bifenthrin prolongs the opening time of Nav1.8 sodium channels , leading to membrane depolarization and conductance block in the insect nervous system, thereby disrupting neural function. Bifenthrin was effective in inhibiting A. gambiae ( LD 50 =0.15 ng/mg) and C. quinquefasciatus ( LD 50 =0.16 ng/mg). Bifenthrin has good lethality against susceptible and resistant mosquitoes and is very effective in inhibiting blood sucking and can be developed as a mosquito-removal netting material [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82657-04-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0824. | |
| Bifeprunox mesylate | Bifeprunox mesylate is a potent dopamine D2 -like and 5-HT1A receptor partial agonist with pK i s of 7.19 and 8.83 for cortex 5-HT1A and striatum D2, and a pEC 50 of 6.37 for hippocampus 5-HT1A, respectively. Bifeprunox mesylate is an antipsychotic for the research of schizophrenia [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 350992-13-1. Pack Sizes: 5 mg. Product ID: HY-14547A. | |
| Bifonazole | Bifonazole (Bay H-4502) is an imidazole antifungal agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bay H-4502. CAS No. 60628-96-8. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B0301. | |
| Biguanide | Biguanide is an orally active antihyperglycemic agent. Biguanide inhibits mitochondrial ATP production, activates the LKB1-AMPK signaling pathway, and damages the energy homeostasis. Biguanide exhibits potential in ameliorating the type 2 diabetes and the insulin-associated cancers [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 56-03-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121006. | |
| BIIB021 | BIIB021 (CNF2024) is an orally active, fully synthetic inhibitor of HSP90 with a K i and an EC 50 of 1.7 nM and 38 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CNF2024. CAS No. 848695-25-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10212. | |
| BIIB091 | BIIB091 is a potent, selective, orally active and reversible BTK inhibitor, with an IC 50 of <0.5 nM. BIIB091 binds the BTK protein to sequester TYR-551 into an inactive conformation with excellent affinity. BIIB091 can be used for the research of multiple sclerosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2247614-80-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139984. | |
| BIIE-0246 | BIIE-0246 (AR-H 053591) is a potent and selective NPY2R (neuropeptide Y receptor 2) antagonist with an IC 50 value of 15 nM for rat [ 125 I]PYY 3-36. BIIE-0246 decreases the expression of p-AKT S473, P-p44/42 MAPK under the NPY-stimulated. BIIE-0246 reduces albuminuria in ADR nephropathy [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AR-H 053591. CAS No. 246146-55-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101986. | |
| BIIL-260 hydrochloride | BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB 4 antagonist, with anti-inflammatory activity. BIIL-260 hydrochloride interacts with the LTB 4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB 4 receptor on isolated human neutrophil cell membranes with K i values of 1.7 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 192581-24-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114641A. | |
| Bikaverin | Bikaverin (Lycopersin) is a reddish pigment produced by different fungal species. Bikaverin shows antibiotic properties against certain protozoa and fungi [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Lycopersin. CAS No. 33390-21-5. Pack Sizes: 500 μg; 1 mg. Product ID: HY-121004. | |
| Bilastine | Bilastine is an oral histamine H1-receptor antagonist. Bilastine can be used for allergic rhinitis and urticaria studies, and it also improves diabetic nephropathy in mice, showing safety for the central nervous system [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 202189-78-4. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-14447. | |
| Bile extract | Bile extract is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ox bile extract. CAS No. 8008-63-7. Pack Sizes: 5 g. Product ID: HY-N8332. | |
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