MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Azintuxizumab vedotin | Azintuxizumab vedotin (ABBV-838) is an antibody-drug conjugate (ADC) targeting a unique epitope of CD2 subset 1, a cell-surface glycoprotein expressed on multiple myeloma cells[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABBV-838. CAS No. 1826819-58-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99454. |  |
| Azithromycin | Azithromycin is a macrolide antibiotic useful for the treatment of a number of bacterial infections. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 62993. CAS No. 83905-01-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-17506. | |
| Azithromycin hydrate | Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-62993 dihydrate. CAS No. 117772-70-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-17506A. | |
| AZM475271 | AZM475271 (M475271) is an orally active and selective Src kinase inhibitor. AZM475271 inhibits phosphorylation of c-Src kinase, Lck, c-yes (IC50s = 0.01, 0.03, 0.08 ?M, respectively). AZM475271 induces apoptosis. AZM475271 reduces tumor cell proliferation and migration in vitro and in vivo, and reduces microvessel density (MVD). AZM475271 inhibits tumor growth and metastasis. AZM475271 sensitizes tumor cells to the cytotoxic effects of Gemcitabine (HY-17026)[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M475271. CAS No. 476159-98-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13561. | |
| Azobenzene | Azobenzene can be used as an optical trigger for the design and synthesis of a large variety of photoresponsive systems. Uses: Scientific research. Group: Signaling pathways. CAS No. 103-33-3. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-B2127. | |
| Azomethine-H monosodium | Azomethine-H monosodium is a colour-forming reagent. Azomethine-H monosodium is also a reagent for boron determinations [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 5941-7-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-D0797. | |
| Azomycin | Azomycin (2-Nitroimidazole) is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Nitroimidazole. CAS No. 527-73-1. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N0195. | |
| Azoramide | Azoramide is a potent, orally active small-molecule modulator of the unfolded protein response (UPR). Azoramide improves ER protein folding and elevates ER chaperone capacity, which together protects cells against ER stress. Azoramide alleviates PLA2G6 mutant-induced ER stress through modulating unfolded protein response, and enhances the CERB signaling to rescue mitochondrial function, thereby preventing apoptosis of DA neurons. Azoramide has antidiabetic activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 932986-18-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18705. | |
| Azosemide | Azosemide, a sulfonamide loop diuretic, is a potent NKCC1 inhibitor with IC 50 s of 0.246?μM and 0.197?μM for hNKCC1A and NKCC1B, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 27589-33-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107321. | |
| Azoxymethane | Azoxymethane is a colon carcinogen which leads to the formation of DNA adducts. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AOM. CAS No. 25843-45-2. Pack Sizes: 5 mg (135 mM * 500 μL in Water); 10 mg (135 mM * 1 mL in Water); 25 mg (135 mM * 2.5 mL in Water); 50 mg (135 mM * 5 mL in Water); 100 mg (135 mM * 10 mL in Water). Product ID: HY-111375. | |
| Azoxystrobin | Azoxystrobin is an orally active, broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 131860-33-8. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-B0849. | |
| AZ PFKFB3 26 | AZ PFKFB3 26 is a potent and selective PFKFB3 inhibitor with an IC50 of 23 nM. AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 ?M, respectively. AZ PFKFB3 26 can be used in the study of non-small cell lung cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1704740-52-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101971. | |
| AZ-PFKFB3-67 | AZ-PFKFB3-67 is a potent and selective PFKFB3 kinase inhibitor with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1, respectively. AZ-PFKFB3-67 reduces MCL-1. AZ-PFKFB3-67 has neuroprotective activity[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1704741-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101972. | |
| Aztreonam | Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SQ-26,776. CAS No. 78110-38-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0129. | |
| Azulene | Azulene (Cyclopentacycloheptene) is as an isomer of naphthalene with high anti-HIV activity. Azulene, isolated from the distillation of chamomile oil, is a scaffold in medicinal chemistry [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Cyclopentacycloheptene. CAS No. 275-51-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B0055. | |
| Azumolene | Azumolene (EU4093 free base), a Dantrolene analog, is a muscle relaxant. Azumolene is a ryanodine receptor (RyR) modulator and inhibits the calcium-release through ryanodine receptor. Azumolene can be used for malignant hyperthermia research[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EU4093 free base. CAS No. 64748-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113920A. | |
| Azure A chloride | Azure A (chloride) is a phenothiazine dye. Azure A (chlorine) is formed by oxidation of methylene blue and has strong metachromatic. Azure A (chlorine) can be used for the study of stains and redox media for electrochemical biosensing [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 531-53-3. Pack Sizes: 1 g; 5 g. Product ID: HY-D0947. | |
| B022 | B022 is a potent and selective NF-?B-inducing kinase (NIK) inhibitor (Ki of 4.2 nM; IC50=15.1 nM). B022 protects liver from toxin-induced inflammation, oxidative stress, and injury[1][2]. B022 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1202764-53-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120501. | |
| B220 | B220 is an antiviral agent which can inhibit the growth of HSV-1 , HSV-2 and human cytomegalovirus ( CMV ). Uses: Scientific research. Group: Signaling pathways. CAS No. 112228-65-6. Pack Sizes: 10 mM * 1 mL; 1 mg. Product ID: HY-100272. | |
| Bacampicillin hydrochloride | Bacampicillin hydrochloride is a penicillin antibiotic, is a prodrug of ampicillin with improved oral bioavailability. Uses: Scientific research. Group: Signaling pathways. CAS No. 37661-08-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B1149A. | |
| Baccatin III | Baccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs [1]. Uses: Scientific research. Group: Natural products. CAS No. 27548-93-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N6985. | |
| Bacitracin | Bacitracin is a polypeptide antibiotic against staphylococcal and pathogenic protozoa infections. Bacitracin inhibits cell wall biosynthesis and permeability through binding to the undecaprenyl pyrophosphate. Bacitracin inhibits macromolecular synthesis. Bacitracin is also a protein disulfide isomerase ( PDI ) inhibitor [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1405-87-4. Pack Sizes: 100 mg. Product ID: HY-107193. | |
| Bacitracin Zinc | Bacitracin Zinc is a complex formed by the binding of Bacitracin (HY-107193) with zinc ions. Bacitracin Zinc is an orally active polypeptide antibiotic with bactericidal properties. Bacitracin Zinc can cause DNA and deoxyribose damage, as well as improve the gut microbiota of broiler and beef cattle [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Zinc bacitracin. CAS No. 1405-89-6. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0278. | |
| Baclofen | Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABA B receptor (GABA B R) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABA B receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1134-47-0. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-B0007. | |
| Baclofen-d4 | Baclofen-d 4 is the deuterium labeled Baclofen. Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1189938-30-4. Pack Sizes: 1 mg. Product ID: HY-B0007S. | |
| Bacoside A3 | Bacoside A3 is a triterpenoid saponin isolated from Bacopa monnieri. Bacoside A3 has neuroprotective activity, downregulating β-amyloid-induced inflammatory responses and inhibiting neuronal apoptosis. Bacoside A3 can be used in the study of Alzheimer's disease [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 157408-08-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N5064. | |
| Bacterial α-Amylase | Bacterial α-Amylase catalyses the hydrolysis of internal α-1,4-glycosidic linkages in starch in low molecular weight products, such glucose, maltose and maltotriose units. Bacterial α-Amylase is often used in biochemical studies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9000-85-5. Pack Sizes: 10 g. Product ID: HY-P2968. | |
| Bafetinib | Bafetinib is an orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib enhances the activity of several pro-apoptotic Bcl-2 homology (BH) 3-pure proteins (Bim, Bad, Bmf, and Bik) through intrinsic apoptotic pathways regulated by the Bcl-2 family, and induces apoptosis of Ph+ leukemia cells. Bafetinib has antitumor activity[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INNO-406; NS-187. CAS No. 859212-16-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50868. | |
| Bafilomycin A1 | Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H + -ATPase ( V-ATPase ) with IC 50 values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: BafA1. CAS No. 88899-55-2. Pack Sizes: 100 μg; 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-100558. | |
| Bafilomycin D | Bafilomycin D is a specific inhibitor of vacuolar-type ATPase ( V-ATPase ). Bafilomycin D has antimicrobial, insecticidal, herbicidal and cytotoxic activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 98813-13-9. Pack Sizes: 1 mg. Product ID: HY-108970. | |
| Bafisontamab | Bafisontamab (EMB-01) is a bispecific antibody targeting EGFR and cMET with antitumor activity[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: EMB-01. CAS No. 2437210-79-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99455. | |
| BAI1 | BAI1 is a selective and allosteric inhibitor of BAX , an apoptosis regulator. BAI1 directly binds to BAX and allosterically inhibits BAX activation. BAI1 has the potential for the research of diseases mediated by BAX-dependent cell death [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 335165-68-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103269. | |
| BAI1 hydrochloride | BAI1 hydrochloride is a selective apoptosis factor BAX allosteric inhibitors. BAI1 hydrochloride binds BAX and allosterically inhibits its activation. BAI1 hydrochloride has the potential to be used in the study of BAX dependent cell death-mediated diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 329349-20-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-110031. | |
| Baicalein | Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor with an IC 50 value of 3.12 μM. Uses: Scientific research. Group: Natural products. Alternative Names: 5,6,7-Trihydroxyflavone. CAS No. 491-67-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0196. | |
| Baicalin | Baicalin, as a flavonoid glycoside, is an allosteric carnitine palmityl transferase 1 ( CPT1 ) activator. Baicalin reduces the expression of NF-κB [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Baicalein 7-O-β-D-glucuronide. CAS No. 21967-41-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0197. | |
| Baicalin (Standard) | Baicalin (Standard) is the analytical standard of Baicalin. This product is intended for research and analytical applications. Baicalin, as a flavonoid glycoside, is an allosteric carnitine palmityl transferase 1 (CPT1) activator. Baicalin reduces the expression of NF-κB [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 21967-41-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0197R. | |
| Bakuchiol | Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 ( UGT2B7 ) [2] and human carboxylesterase 2 ( hCE2 ) [3] , with IC 50 s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory [5] , antibacterial [4] , antitumor [1] therapies, as well as drug metabolism regulation. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-(+)-Bakuchiol. CAS No. 10309-37-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0235. | |
| Balaglitazone | Balaglitazone is a selective partial PPARγ agonist with an EC 50 of 1.351 μM for human PPAR&gamma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DRF 2593; NN 2344. CAS No. 199113-98-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16086. | |
| Balapiravir | Balapiravir (Ro 4588161; R1626) is an orally active proagent of a nucleoside analogue inhibitor of the RNA-dependent RNA polymerase (RdRp) of HCV (R1479; 4'-Azidocytidine). Balapiravir has anti- HCV activity [1] [2] [3]. Balapiravir is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 4588161; R1626. CAS No. 690270-29-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10443. | |
| Balcinrenone | Balcinrenone (AZD9977) is a potent, selective, and orally active mineralocorticoid receptor (MR) modulator. Balcinrenone is used for heart failure, and chronic kidney disease research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD9977. CAS No. 1850385-64-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120274. | |
| Balicatib | Balicatib (AAE581) is a potent, orally active and selective cathepsin K inhibitor with IC50 values of 22, 61, 48, 2900 nM for cathepsin K, cathepsin B, cathepsin L, cathepsin S, respectively. Balicatib inhibits bone turnover, decreases bone formation rates. Balicatib has the potential for the research of osteoporosis[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AAE581. CAS No. 354813-19-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15100. | |
| Balinatunfib | Balinatunfib (SAR-441566) is an orally active inhibitor of TNFR1 signaling. By binding to the central pocket of the soluble TNF? (sTNF?) trimer, Balinatunfib stabilizes an asymmetric conformation, blocking its binding to TNFR1 (without affecting TNFR2) and thus inhibiting downstream pathways. Balinatunfib has anti-inflammatory activity, and can be used in the study of autoimmune diseases[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAR-441566; TNF? activity modulator 3. CAS No. 2248726-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160412. | |
| Balipodect | Balipodect (TAK-063) is a highly potent, selective and orally active PDE10A inhibitor with IC50 of 0.30 nM; >15000-fold selectivity over other PDEs. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-063. CAS No. 1238697-26-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12472. | |
| Balovaptan | Balovaptan (RG7314) is an orally available, selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with K i s of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors, and is used for the research of autism. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG7314. CAS No. 1228088-30-9. Pack Sizes: 10 mM * 1ML; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109024. | |
| Baloxavir | Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Baloxavir acid; S-033447. CAS No. 1985605-59-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109025A. | |
| Baloxavir marboxil | Baloxavir marboxil (S-033188) is a selective inhibitor of influenza cap-dependent endonuclease. Baloxavir marboxil, a potent antiviral agent, shows activity against influenza A and B virus [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-033188; RG 6152. CAS No. 1985606-14-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-109025. | |
| Balsalazide | Balsalazide is a prodrug of amino salicylic acid that releases mesalamine (HY-15027) in the colon, offering various anti-inflammatory effects in areas of colitis, and it also exerts related anticancer effects by regulating the IL-6/STAT3 pathway [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80573-04-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0667. | |
| Balsalazide sodium hydrate | Balsalazide sodium hydrate is a prodrug of amino salicylic acid that releases mesalamine (HY-15027) in the colon, offering various anti-inflammatory effects in areas of colitis, and it also exerts related anticancer effects by regulating the IL-6/STAT3 pathway [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Balsalazide disodium dihydrate. CAS No. 150399-21-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0667A. | |
| Balstilimab | Balstilimab (AGEN2034) is a fully human monoclonal IgG4 antibody against PD-1 [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AGEN2034. CAS No. 2148321-77-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99457. | |
| BAM 15 | BAM 15 is a mitochondrial protonophore uncoupler. BAM 15 is an oxidative phosphorylation ( OXPHOS ) uncoupler [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 210302-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110284. | |
| BAM(8-22) | BAM(8-22), a proteolytically cleaved product of proenkephalin A and sensory neuron-specific receptor ( SNSR ) agonist, is a potent activator of Mas-related G-protein-coupled receptors ( Mrgprs ), MrgprC11 and hMrgprX1. BAM(8-22) induces scratching in mice in an Mrgpr -dependent manner. In addition, BAM(8-22) has an analgesic effect and can also inhibit the activation of microglia [1] [2] [3] [4]. Uses: Scientific research. Group: Peptides. CAS No. 412961-36-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1241. | |
| Bambuterol hydrochloride | Bambuterol hydrochloride ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a proagent of terbutaline. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Bambuterol hydrochloride; KWD-2183 hydrochloride. CAS No. 81732-46-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17501A. | |
| Baminercept | Baminercept (BG 9924) is an anti-lymphotoxin ? receptor (LT?R) IgG fusion protein (LT?R-Ig). Baminercept selectively binds to the LT?R ligand LT?/? heterotrimer and LIGHT, block the LT?R signaling pathway, and inhibits the expression of chemokines such as CXCL13. Baminercept also regulates peripheral blood B cell and T cell subsets, reduces the transcription of IFN-induced genes. Thereby, Baminercept inhibits the formation of high endothelial venules and reticular structures in lymphoid tissues, and affects immune cell migration. Baminercept can be used for the study of autoimmune diseases such as primary Sjogren's syndrome (pSS) and rheumatoid arthritis (RA)[1][2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BG 9924; TT-47. CAS No. 909110-25-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99459. | |
| Bamlanivimab | Bamlanivimab (Anti-Human SARS-CoV-2) is the first COVID-19 monoclonal antibody (mAb) to be granted Emergency Use Authorization (EUA) in November 2020 by the U.S. Food and agent Administration (FDA). However, Bamlanivimab is withdrawn in April 2021 following the rise of SARS-CoV-2 virus variants resistant to Bamlanivimab [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human SARS-CoV-2. CAS No. 2423943-37-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99344. | |
| Baohuoside I | Baohuoside I, a flavonoid isolated from Epimedium koreanum Nakai, acts as an inhibitor of CXCR4, downregulates CXCR4 expression, induces apoptosis and shows anti-tumor activity. Uses: Scientific research. Group: Natural products. Alternative Names: Icariin-II; Icariside-II. CAS No. 113558-15-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0011. | |
| b-AP15 | b-AP15 is a specific inhibitor of the deubiquitinating enzymes UCHL5 and Usp14. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 687852. CAS No. 1009817-63-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13989. | |
| BAP1-IN-1 | BAP1-IN-1 (Compound 8) is a BRCA1 associated protein 1 (BAP1) catalytic activity inhibitor with an IC50 of 0.1-1 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 353495-21-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-W327122. | |
| Bapineuzumab | Bapineuzumab is an anti-β-amyloid protein (APP) monoclonal antibody. Bapineuzumab can be used for the research of Alzheimers disease (AD) [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 648895-38-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99185. | |
| BAPTA | BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca 2+ release from intracellular stores or influx via Ca 2+ -permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 85233-19-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-100168. | |
| BAPTA-AM | BAPTA-AM is a well-known membrane permeable Ca2+ chelator. BAPTA-AM inhibits hERG channels, hKv1.3 and hKv1.5 channels in HEK 293 cells with IC50s of 1.3 ?M, 1.45 ?M and 1.23 ?M, respectively[1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 126150-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100545. | |
| BAPTA tetrapotassium | BAPTA tetrapotassium is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca 2+ release from intracellular stores or influx via Ca 2+ -permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators [1] [2] [4]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 73630-08-7. Pack Sizes: 100 mg; 250 mg. Product ID: HY-100168B. | |
| BAPTA tetrasodium | BAPTA tetrasodium is a selective chelator for calcium. BAPTA tetrasodium, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrasodium is widely used as an intracellular buffer for investigating the effects of Ca 2+ release from intracellular stores or influx via Ca 2+ -permeable channels in the plasma membrane. BAPTA tetrasodium can also inhibit phospholipase C activity independently of their role as Ca 2+ chelators [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 126824-24-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-100168A. | |
| Baptifoline | Baptifoline is an alkaloid isolated from the rhizome of Caulophyllum thalictroides [1]. Uses: Scientific research. Group: Natural products. CAS No. 732-50-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7792. | |
| BAR501 | BAR501 is a potent and selective agonist of GPBAR1 with an EC50 of 1 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 1632118-69-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101274. | |
| BAR502 | BAR502 is a dual FXR and GPBAR1 agonist with IC 50 values of 2 μM and 0.4 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1612191-86-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101273. | |
| Barasertib | Barasertib (AZD1152), a pro-drug of Barasertib-hQPA, is a highly selective Aurora B inhibitor with an IC50 of 0.37 nM in a cell-free assay. Barasertib (AZD1152) induces growth arrest and apoptosis in cancer cells[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD1152. CAS No. 722543-31-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10127. | |
| Barasertib-HQPA | Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor with an IC50 of 0.37 nM in a cell-free assay. Barasertib-HQPA (AZD2811) induces growth arrest and apoptosis in cancer cells[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD2811; INH-34; AZD1152-HQPA. CAS No. 722544-51-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10126. | |
| Barbadin | Barbadin is a novel and selective ?-arrestin/?2-adaptin interaction inhibitor, has IC50 values of 19.1 ?M for ?-arrestin1 and 15.6 ?M for ?-arrestin2. Barbadin blocks agonist-promoted endocytosis of the prototypical ?2-adrenergic, V2-vasopressin and angiotensin-II type-1 receptors. Barbadin can induce apoptosis[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 356568-70-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-119706. | |
| Bardoxolone | Bardoxolone (RTA 401; CDDO) is a novel nuclear regulatory factor ( NRf-2 ) activator. Bardoxolone is a potent necroptosis inhibitor that inhibits Z-VAD-FMK-induced necroptosis. Bardoxolone methyl enhances the antioxidant system, modulates inflammatory cytokines and inhibits apoptosis in rat kidney, demonstrating inhibition on APAP-induced acute kidney injury (AKI) and analgesic effect. Additionally, Bardoxolone methyl decreases Paclitaxel (PAC) (HY-B0015)-induced mitochondrial damage in neuronal cells. Bardoxolone methyl is promising for the research of chemotherapy-induced neuropathic pain and chronic kidney disease [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDDO; RTA 401. CAS No. 218600-44-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14909. | |
| Bardoxolone methyl | Bardoxolone methyl (NSC 713200; RTA 402; CDDO Methyl ester) is a synthetic triterpenoid compound with potential antineoplastic and anti-inflammatory activities, acting as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RTA 402; NSC 713200; CDDO Methyl ester. CAS No. 218600-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13324. | |
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