MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Bismuth subcitrate potassium | Bismuth subcitrate potassium is a compound bismuth salt with oral activity. Bismuth subcitrate potassium has antibacterial activity and can inhibit the growth of Campylobacter pyloridis with a MIC 50 of 8 μg/mL. Bismuth subcitrate potassium can be used in the study of gastrointestinal diseases infected by Campylobacter pyloridis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 880149-29-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-16102. |  |
| Bisoctrizole | Bisoctrizole is a broad-spectrum UV absorber that absorbs UVB and UVA rays while reflecting and scattering UV rays. Uses: Scientific research. Group: Signaling pathways. CAS No. 103597-45-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0897. | |
| Bisoprolol | Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker with little activity on β2-receptor. Bisoprolol has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66722-44-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129029. | |
| Bis-PEG3-acid | Bis-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 96517-92-9. Pack Sizes: 100 mg; 250 mg. Product ID: HY-126891. | |
| Bisphenol A | Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cancers, cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Natural products. CAS No. 80-05-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-18260. | |
| Bisphenol A-d16 | Bisphenol A-d 16 is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 96210-87-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18260S. | |
| Bisphenol A-d6 | Bisphenol A-d 6 is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 86588-58-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-18260S1. | |
| Bisphenol A (Standard) | Bisphenol A (Standard) is the analytical standard of Bisphenol A. This product is intended for research and analytical applications. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 80-05-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18260R. | |
| Bisphenol B | Bisphenol B is a very close structural analog of Bisphenol A (HY-18260), an endocrine disrupting chemical (EDC) and a substance of very high concern (SVHC) in the European Union (EU) for both human health. Bisphenol B shows endocrine disruptive properties or other adverse effects on animal models [1]. Uses: Scientific research. Group: Natural products. CAS No. 77-40-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-W013935. | |
| Bis(pinacolato)diborane | Bis(pinacolato)diborane is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 73183-34-3. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-79444. | |
| Bispyribac sodium | Bispyribac sodium is a selective, systemic and post emergent herbicide used to eradicate grasses and broad leaf weeds. Bispyribac sodium is also an acetolactate synthase (ALS or known as AHAS) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 125401-92-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0869A. | |
| Bis-Tos-PEG4 | Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PROTAC Linker 16. CAS No. 37860-51-8. Pack Sizes: 50 g; 100 g. Product ID: HY-W004816. | |
| Bistrifluron | Bistrifluron has insecticidal effects on the larval stage, and also has an effect on adult longevity, reproduction, and hatchability. Bistrifluron is used for the control of a variety of Lepidopterous pests [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 201593-84-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119902. | |
| Bis(trimethylsilyl)acetylene | Bis(trimethylsilyl)acetylene is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 14630-40-1. Pack Sizes: 5 g; 10 g. Product ID: HY-W016961. | |
| Bis-Tris | Bis-Tris is an amine buffer suitable for protein and nucleic acid systems with a pH buffer range of 5.8-7.2. Bis-Tris can also be mixed with HEPES and cacodylic acid buffer to create a pH 8 environment and monitor fluorescence emission intensity at 305 nm. Gels formulated with Bis-Tris also avoid protein degradation in samples prepared at higher pH (pH 8.5) [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 6976-37-0. Pack Sizes: 25 g; 50 g. Product ID: HY-D0856. | |
| Bis-Tris hydrochloride | Bis-Tris hydrochloride is a biological buffer , and can be used in gel electrophoresis separations, cell culture and bioprocessing applications [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 124763-51-5. Pack Sizes: 10 g; 25 g. Product ID: HY-W105681. | |
| Bis-tris propane | Bis-tris propane (BTP) is a water-soluble buffer substance. Bis-tris propane can be used as a suitable buffer for polymerase chain reaction (PCR). Bis-tris propane can enhance the stability or activity of restriction enzymes [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: BTP. CAS No. 64431-96-5. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-126399. | |
| Bis(tri-tert-butylphosphine)palladium(0) | Bis(tri-tert-butylphosphine)palladium(0) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 53199-31-8. Pack Sizes: 250 mg; 1 g. Product ID: HY-W010772. | |
| BIT-225 | BIT-225 is an inhibitor for Vpu protein through block of Vpu ion channel, and thus inhibits the release of HIV-1 , especially in monocyte-derived macrophages ( EC 50 is 2.25 μM), without significant cytotoxicity (TC 50 is 284 μM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 917909-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106282. | |
| Bithionol | Bithionol is an antibacterial, anthelmintic, and algaecide agent. Bithionol is also a potent inhibitor of soluble adenylyl cyclase through binding to the allosteric activator site (IC 50 : 4 μM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 97-18-7. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-17592. | |
| Bitolterol mesylate | Bitolterol mesylate (WIN 37284) is a diester-type agonist amine bronchodilator without significant cardiac side effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Win 32784; Bitolterol methanesulfonate; S-1540 mesylate. CAS No. 30392-41-7. Pack Sizes: 5 mg. Product ID: HY-16103. | |
| Bitopertin | Bitopertin is a potent, noncompetitive glycine reuptake inhibitor, inhibits glycine uptake at human GlyT1 with a concentration exhibiting IC50 of 25 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG1678; RO4917838. CAS No. 845614-11-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10809. | |
| Bivalirudin | Bivalirudin, a peptide anticoagulant, is a direct thrombin inhibitor for anticoagulation in the setting of invasive cardiology, particularly percutaneous coronary intervention [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 128270-60-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1929. | |
| Bivalirudin TFA | Bivalirudin TFA is a synthetic 20 residue peptide which reversibly inhibits thrombin. Uses: Scientific research. Group: Peptides. CAS No. 1191386-55-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15664. | |
| Bivamelagon | MC-4R Agonist 2 (Example 1) is a MC4R agonist. MC-4R Agonist 2 can be used in the study of obesity, diabetes, inflammation, and erectile dysfunction [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MC-4R Agonist 2. CAS No. 2641595-54-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-153660. | |
| Bivatuzumab | Bivatuzumab (Anti-CD44 Recombinant Antibody; BIWA 4) is a humanized monoclonal antibody directed against CD44v6. CD44v6 could acts as a sarcoma target for CAR-redirected CIK cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BIWA 4; Anti-CD44 Recombinant Antibody. CAS No. 214559-60-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99281. | |
| BIX-01338 hydrate | BIX-01338 hydrate is a histone lysine methyltransferase inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1228184-65-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12991A. | |
| Bixin | Bixin (BX), isolated from the seeds of Bixa orellana , is a carotenoid, possessing anti-inflammatory, anti-tumor and anti-oxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation and reactive oxygen species ( ROS ) generation [1]. Uses: Scientific research. Group: Natural products. CAS No. 6983-79-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N6884. | |
| Blarcamesine | Blarcamesine is an orally bioavailable Sigma-1 receptor agonist and muscarinic receptor modulator, with anticonvulsant, anti-amnesic, neuroprotective and antidepressant properties. Blarcamesine ameliorates neurologic impairments in a mouse model of Rett syndrome [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 195615-83-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105296. | |
| Blarcamesine hydrochloride | Blarcamesine hydrochloride (Anavex 2-73) is a Sigma-1 Receptor agonist with an IC 50 of 860 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Anavex 2-73. CAS No. 195615-84-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101864. | |
| Blebbistatin | Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function. Blebbistatin blocks cell migration [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 674289-55-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13813. | |
| (-)-Blebbistatin | (-)-Blebbistatin is a selective inhibitor of the ATPase activity of non-muscle myosin II [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 856925-71-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13441. | |
| (+)-Blebbistatin | (+)-Blebbistatin is the inactive enantiomer of ( - )-Blebbistatin. ( - )-Blebbistatin is a selective inhibitor of myosin II ATPase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1177356-70-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107657. | |
| Bleomycin hydrochloride | Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67763-87-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17565A. | |
| Bleomycin sulfate | Bleomycin sulfate is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin sulfate is an antitumor antibiotic [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Bleomycin sulfate. CAS No. 9041-93-4. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-17565. | |
| Bleselumab | Bleselumab (ASKP 1240) is a human anti- CD40 monoclonal antibody (mAb). Bleselumab binds to human CD40 with high affinity ( K d : 0.24 nM). Bleselumab inhibits immune responses by blocking the interaction of CD40 with its ligand CD40L. Bleselumab prevents organ transplant rejection [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ASKP 1240; Anti-Human CD40 Recombinant Antibody. CAS No. 1453067-91-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99257. | |
| Bleximenib | Bleximenib (JNJ-75276617; Menin-MLL inhibitor 24) is a potent, selective and orally active menin-KMT2A protein-protein interaction inhibitor with IC 50 values of 0.1, 0.045, ≤0.066 nM for human, mouse, dog, respectively. Bleximenib shows antiproliferative activity and induces apoptosis. Bleximenib has the potential for the research of Acute myeloid leukemia (AML) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-75276617; Menin-MLL inhibitor 24. CAS No. 2654081-35-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-148669. | |
| Bleximenib oxalate | Bleximenib (JNJ-75276617; Menin-MLL inhibitor 24) oxalate is a potent, selective and orally active menin-KMT2A protein-protein interaction inhibitor with IC 50 values of 0.1, 0.045, ≤0.066 nM for human, mouse, dog, respectively. Bleximenib oxalate shows antiproliferative activity and induces apoptosis. Bleximenib oxalate has the potential for the research of Acute myeloid leukemia (AML) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-75276617 oxalate; Menin-MLL inhibitor 24 oxalate. CAS No. 2866179-95-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148669A. | |
| Blinatumomab | Blinatumomab (Anatumomab) is a bispecific monoclonal antibody with two binding sites, one for CD3E on T cells and one for CD19 on B cells. Blinatumomab can be used in research for acute lymphoblastic leukemia [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anatumomab. CAS No. 853426-35-4. Pack Sizes: 100 μg; 500 μg; 1 mg; 5 mg. Product ID: HY-P9963. | |
| Bliretrigine | Bliretrigine is a sodium channel blocker. Bliretrigine has the effect of relieving pain [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1233229-75-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145558. | |
| Blonanserin | Blonanserin (AD-5423) is a potent and orally active 5-HT 2A ( K i =0.812 nM) and dopamine D2 receptor ( K i =0.142 nM) antagonist. Blonanserin is usually acts as an atypical antipsychotic agent and can be used for the research of extrapyramidal symptoms, excessive sedation, or hypotension [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AD-5423. CAS No. 132810-10-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13575. | |
| Blosozumab | Blosozumab (LY2541546) is an anti-Human sclerostin (SOST) antibody inhibitor. Blosozumab stimulates bone formation and reduces bone resorption. Blosozumab can be used in the research of Osteoporosis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1132758-87-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99186. | |
| BLU-945 | BLU-945 is a potent, highly selective, reversible and orally active epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKIs). BLU-945 can effectively inhibit EGFR with L858R and/or exon 19 deletion mutation, T790M mutation and C797S mutation. BLU-945 can be used for the research of lung cancer including non-small cell lung cancer (NSCLC) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZL-2313. CAS No. 2660250-10-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-144680. | |
| Blumeatin | Blumeatin, isolated from Blumea balsamifera DC, could protect liver against injury induced by CCl4 and thioacetamide (TAA) [1]. Uses: Scientific research. Group: Natural products. CAS No. 118024-26-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2358. | |
| BM635 | BM635 is a MmpL3 inhibitor with outstanding anti-mycobacterial activity. BM635 has an MIC 50 of 0.12 μM against M. tuberculosis H37Rv. Uses: Scientific research. Group: Signaling pathways. CAS No. 1493762-74-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109587. | |
| BM-962 | BM-962 (Compound 31) is a potent small-molecule inhibitor of Bcl-2 with an IC 50 value of 4 nM ( K i =0.8 nM) and Bcl-xL with an IC 50 value of 3.9 nM ( K i <1 nM). BM-962 inhibits the cell growth in H1417 and H146 cell lines with IC 50 values of 9 and 13 nM, respectively. BM-962 is promising for research of cancers [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1391107-57-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-169925. | |
| BMF-219 | Menin-MLL inhibitor 21 (example 9) is a specific, irreversible inhibitor of Menin-MLL interaction, useful for the study of autoimmune diseases, heteroimmune diseases, cancer, and other diseases dependent on menin-MLL. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Menin-MLL inhibitor 21. CAS No. 2448172-22-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150105. | |
| BMH-21 | BMH-21 is a first-in-class DNA intercalator which inhibits RNA polymerase I ( Pol I ) transcription. BMH-21 possesses anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 896705-16-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12484. | |
| BML-278 | BML-278 is a SIRT1 activator ( EC 150 : 1 μM). BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in both the paternal and maternal pronucleus. BML-278 improves early embryonic development. BML-278 arrests the cell cycle at the G1/S phase, and reduces senescence in primary human mesenchymal cells. BML-278 reduces tubulin acetylation in U937 cells. BML-278 also increases mitochondrial density in murine C2C12 myoblasts [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120533-76-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W025074. | |
| BMPO | BMPO (BocMPO) is a cell-permeable superior spin trap with favorable chemical and spectroscopic features. BMPO (BocMPO) can be used for detecting thiyl radicals, hydroxyl radicals, superoxide anions and glutathiyl radicals [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BocMPO. CAS No. 387334-31-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121137. | |
| BMPS | BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Group: Signaling pathways. CAS No. 55750-62-4. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-42146. | |
| BMS 182874 | BMS 182874 is an orallyactive, highly selective endothelin receptor ( ET A receptor) antagonist, with IC 50 value of 0.150 μM, K i of 0.055 μM. BMS 182874 reduces the arterial pressure of Deoxycorticosterone acetate (HY-B1472) induced hypertension model in rats, and can be used for cardiovascular disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 153042-42-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118497. | |
| BMS-202 | BMS-202 is a potent and nonpeptidic PD-1/PD-L1 complex inhibitor with an IC 50 of 18 nM and a K D of 8 μM. BMS-202 binds to PD-L1 and blocks human PD-1/PD-L1 interaction. BMS-202 has antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1675203-84-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19745. | |
| BMS-345541 | BMS-345541 is a selective inhibitor of the catalytic subunits of IKK ( IKK-2 IC 50 =0.3 μM, IKK-1 IC 50 =4 μM). BMS-345541 binds at an allosteric site of IKK. Uses: Scientific research. Group: Signaling pathways. CAS No. 445430-58-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10519. | |
| BMS-345541 hydrochloride | BMS-345541 hydrochloride is a selective inhibitor of the catalytic subunits of IKK ( IKK-2 IC 50 =0.3 μM, IKK-1 IC 50 =4 μM). BMS-345541 binds at an allosteric site of IKK. Uses: Scientific research. Group: Signaling pathways. CAS No. 547757-23-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10518. | |
| BMS-536924 | BMS-536924 is an orally active, competitive and selective insulin-like growth factor receptor (IGF-1R) kinase and insulin receptor (IR) inhibitor with IC 50 s of 100 nM and 73 nM, respectively. BMS-536924 has anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 468740-43-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10262. | |
| BMS-582949 hydrochloride | BMS-582949 hydrochloride is an orally active and highly selective p38α MAPK inhibitor, with an IC 50 of 13 nM. BMS-582949 hydrochloride displays a significantly improved pharmacokinetic profile and is effective in inflammatory disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 912806-16-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14305A. | |
| BMS-599626 Hydrochloride | BMS-599626 Hydrochloride (AC480 Hydrochloride) is a selective and orally bioavailable HER1 and HER2 inhibitor, with IC 50 s of 20 and 30 nM, respectively. BMS-599626 Hydrochloride displays ~8-fold less potent to HER4 (IC 50=190 nM), >100-fold to VEGFR2, c-Kit, Lck, MEK. BMS-599626 Hydrochloride inhibits tumor cell proliferation, and has potential to increase tumor response to radiotherapy [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AC480 Hydrochloride. CAS No. 873837-23-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12010. | |
| BMS-754807 | BMS-754807 is a potent and reversible IGF-1R / IR inhibitor ( IC 50 =1.8 and 1.7 nM, respectively; K i =<2 nM for both). BMS-754807 also shows potent activities against Met, RON, TrkA, TrkB, AurA, and AurB with IC 50 values of 6, 44, 7, 4, 9, and 25 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1001350-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10200. | |
| BMS 777607 | BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met , Axl , Ron and Tyro3 with IC 50 s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS 817378. CAS No. 1025720-94-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12076. | |
| BMS-813160 | BMS-813160 is a potent and selective CCR2/5 dual antagonist. BMS-813160 binds with CCR2 and CCR5 with IC 50 s of 6.2 and 3.6 nM, respectively. BMS-813160 can be used for the research of inflammation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1286279-29-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109593. | |
| BMS-911543 | BMS-911543 is a selective JAK2 inhibitor, with IC 50 s of 1.1 nM, less selective at JAK1, JAK3 and TYK2 ( IC 50 , 75, 360, 66 nM, respectively). Uses: Scientific research. Group: Signaling pathways. CAS No. 1271022-90-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15270. | |
| BMS-978587 | BMS-978587 (IDO-IN-4) is an indoleamine 2,3-dioxygenase 1 ( IDO-1 ) inhibitor, extracted from patent WO2014150677A1, Compound example 1 enantiomer 1. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IDO-IN-4. CAS No. 1629125-65-0. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18769. | |
| BMS-986094 | BMS-986094 (INX-08189) is a potent inhibitor of hepatitis C virus (HCV) replication, with an EC 50 of 35 nM at 24 h in Huh-7 cells. BMS-986094 is a phosphoramidate proagent of 6-O-methyl-2-C-methyl guanosine. BMS-986094 can be used for the research of chronic HCV infection [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INX-08189. CAS No. 1234490-83-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13337. | |
| BMS-986120 | BMS-986120 is a first-in-class oral and reversible protease-activated receptor 4 ( PAR4 ) antagonist, with IC 50 s of 9.5 nM and 2.1 nM in human and monkey blood, respectively. BMS-986120 has potent and selective antiplatelet effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1478712-37-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19837. | |
| BMS-986158 | BMS-986158 is a potent BET inhibitor with IC 50 s of 6.6 and 5?nM in NCI-H211 small cell lung cancer (SCLC) cells and MDA-MB231 triple negative breast cancer (TNBC) cells, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1800340-40-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-101567. | |
| BMS-986187 | BMS-986187 is an δ-opioid receptor -selective positive allosteric modulator (PAM) with an EC 50 of 0.03 μM and a pK B of 6.02 (~1 μM). BMS-986187 has no observable PAM activity at the μ-receptor (EC 50 =3 μM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 684238-37-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120613. | |
| BMS-986278 | BMS-986278 is a potent and orally active lysophosphatidic acid receptor 1 (LPA1) antagonist, with K b s of 6.9 nM and 4.0 nM for human and mouse LPA1, respectively. BMS-986278 can be used for the research of pulmonary fibrotic diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2170126-74-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139853. | |
| BMS-986299 | BMS-986299 (compound 112) is a first-in-class NLRP3 inflammasome agonist with an EC 50 of 1.28 μM. (patent WO2018152396A1). Uses: Scientific research. Group: Signaling pathways. CAS No. 2242952-69-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139396. | |
| BMS-986365 | BMS-986365 (CC-94676) is an orally active and selective targeted androgen receptor ( AR ) PROTAC degrader, capable of inducing cereblon (CRBN) E3 ligase-dependent ubiquitination and degradation of the androgen receptor ( AR ), as well as various AR mutants. BMS-986365 shows significant in vivo potency, degrading AR , inhibiting AR signaling, and restricting tumor growth in animal models of advanced prostate cancer. (Blue: HY-W247437; Black: linker (HY-W126831); Pink: HY-168697) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-94676. CAS No. 2446928-30-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158101. | |
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