MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Bazedoxifene (acetate)-D | Bazedoxifene (acetate)-D (TSE-424 (acetate)-D) is the D-crystal form compound of Bazedoxifene acetate (HY-A0036). Bazedoxifene acetate is an orally active, nonsteroidal selective estrogen receptor modulator (SERM), with IC 50 s of 23 nM and 99 nM for ERα and ERβ, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSE-424 (acetate)-D. CAS No. 198481-33-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0036D. |  |
| Bazedoxifene N-Oxide | Bazedoxifene N-Oxide is the oxidative degradation product of selective estrogen receptor modulator (SERM) Bazedoxifene [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1174289-22-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Z0833. | |
| BBD | BBD (NSC240867) is a biochemical reagent/chromogenic reagent. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: NSC240867; Benzylamino-NBD. CAS No. 18378-20-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-15907. | |
| BBO-8520 | BBO-8520 is a direct small molecule covalent inhibitor targeting KRAS G12C with high oral availability. BBO-8520 has the characteristics of KRAS G12C (OFF) inhibitor and the function of blocking KRAS G12C (ON) signal. BBO-8520 inhibits cell proliferation by inhibiting KRAS G12C (ON) by binding GTP protein. BBO-8520 can block RAS-RAF1 interaction and return KRAS G12C to the inactive (OFF) state [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2893809-51-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158107. | |
| BBS-4 | BBS-4 is a potent and selective inducible nitric oxide synthase (NOS2) dimerization inhibitor, with an IC 50 of 0.49 nM. BBS-4 can protect mice from the cardiovascular dysfunction of sepsis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 402934-09-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12124. | |
| BBT | BBT is an enhancer of impaired glucose-stimulated insulin secretion (GSIS). BBT exhibits anti-hyperglycemia activity, and protects β-cells from cytokine- or streptozotocin (STZ (HY-13753))-induced cell death in type 2 diabetes models. BBT acts function via cAMP/PKA and long-lasting (L-type) voltage-dependent Ca2+ channel/ CaMK2 pathway [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 445000-45-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 100 mg. Product ID: HY-Q40876. | |
| BC-11 hydrobromide | BC-11 hydrobromide is a selective TMPRSS2 inhibitor (TMPRSS2 is a key host cellular factor for viral entry and SARS-CoV-2 pathogenesis), and a selective urokinase ( uPA ) inhibitor ( IC 50 =8.2 μM). BC-11 hydrobromide is cytotoxic to triple-negative MDA-MB231 breast cancer cells. BC-11 hydrobromide is used in research on viral infections and cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 443776-49-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-108447. | |
| BCA | BCA (Disodium bicinchoninate) is an orally active and non-competitive Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC 50 value of 28 μM, a K i value of 43 μM. BCA shows anticancer activity. BCA has the potential for the research of Alzheimer's disease (AD) [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Disodium bicinchoninate. CAS No. 979-88-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15908. | |
| BCDA | BCDA (5-bromo-4-chloroindoxyl acetate) is a chromogenic substrate of esterase used to potently detect the activity of esterase [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 5-bromo-4-chloroindoxyl acetate. CAS No. 3252-36-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-52112. | |
| BCECF | BCECF is a pH-sensitive fluorescent dye. BCECF allows measurements in the physiological pH range 6.0 - 8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 2,7-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein. CAS No. 85138-49-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101882. | |
| BCECF-AM | BCECF-AM is a cell membrane permeable compound widely used as a fluorescent indicator for intracellular pH. Uses: Scientific research. Group: Fluorescent dye. CAS No. 117464-70-7. Pack Sizes: 205 μg (5 mM * 50 μL in DMSO); 410 μg (5 mM * 100 μL in DMSO); 820 μg (5 mM * 200 μL in DMSO); 2.05 mg (5 mM * 500 μL in DMSO). Product ID: HY-101883. | |
| BCH | BCH (2-Amino-2-norbornanecarboxylic acid) is a selective and competitive inhibitor of large neutral amino acid transporter 1 (LAT1) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Amino-2-norbornanecarboxylic acid; LAT1-IN-1. CAS No. 20448-79-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-108540. | |
| BChE-IN-17 | BChE-IN-17 (compound 6n) is a potent and selective BChE inhibitor with IC 50 s of 10.5 nM and 32.5 nM for eqBChE and hBChE , respectively. BChE-IN-17 shows over 1000-fold selectivity to BChE against AChE. BChE-IN-17 shows low neurotoxicity and moderate neuroprotective effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2425632-57-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155140. | |
| BCI | BCI ((E)-BCI) is a DUSP6 ( dual specificity phosphatase 6 ) inhibitor. BCI shows anti-inflammatory activity and decreases reactive oxygen species (ROS) production. BCI can be used in inflammatory disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E)-BCI. CAS No. 1245792-51-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-115502. | |
| BCI hydrochloride | BCI ((E)-BCI) hydrochloride is a DUSP6 ( dual specificity phosphatase 6 ) inhibitor. BCI hydrochloride shows anti-inflammatory activity and decreases reactive oxygen species (ROS) production. BCI hydrochloride can be used in inflammatory disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E)-BCI hydrochloride. CAS No. 95130-23-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115502A. | |
| BCIP | BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: BCIP p-toluidine salt; X-phosphate p-toluidine salt. CAS No. 6578-6-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-15909. | |
| BCL6-IN-5 | BCL6-IN-5 is a potent BCL6 inhibitor exacted from patent WO2018215801A1, example 1n, has a pIC 50 of 5.82 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2253878-09-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136774. | |
| BCN-endo-PEG4-NHS | BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. BCN-endo-PEG4-NHS contains the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts. Uses: Scientific research. Group: Signaling pathways. CAS No. 1702356-19-1. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W096079. | |
| BCPA | BCPA is a Pin1 regulator without cytotoxicity. BCPA attenuates the reduction of Pin1 protein to inhibit receptor activator of RANKL-induced osteoclastogenesis. BCPA regulates osteoclast activation, used to osteoporosis research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 547731-67-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153675. | |
| BCR-ABL1-IN-1 | BCR-ABL1-IN-1 is a potent, orally active, and specific inhibitor of ABL kinase. BCR-ABL1-IN-1 has potential for elucidating the role of ABL kinases in the brain in non-clinical studies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1488090-21-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145887. | |
| BCTC | BCTC is an orally active current inhibitor of vanilloid receptor type 1 (VR1). BCTC is a transient receptor potential cation channel subfamily M member 8 (TRPM8) and transient receptor potential vanilloid 1 (TRPV1) antagonist. BCTC is an insulin sensitizer and secretor. BCTC has anticancer and analgesic effects [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 393514-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-19960. | |
| BD-1008 dihydrobromide | BD-1008 dihydrobromide is an antagonist of sigma Receptor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 138356-09-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-100966. | |
| BD1063 dhydrochloride | BD1063 dhydrochloride is a potent and selective sigma 1 receptor antagonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 206996-13-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18101A. | |
| BDC2.5 mimotope | BDC2.5 mimotope is a potent antigen-mimicking peptide that can activate CD4+ T cell populations that have the same antigen recognition properties as BDC2.5 cells. BDC2.5 mimotope can be used to study the prevention or treatment of type 1 diabetes by targeting specific T cell populations [1]. Uses: Scientific research. Group: Peptides. CAS No. 1370451-15-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P10512. | |
| BDC2.5 mimotope 1040-31 | BDC2.5 mimotope 1040-31, a BDC2.5 TCR reactive peptide, is a strong agonistic peptide for diabetogenic T cell clone BDC2.5, and the 1040-31 peptide is specific for BDC 2.5 TCR Tg + T cells [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 329696-49-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1822. | |
| BDE 47 | BDE 47 targets mitochondria, inhibits mitochondrial oxidative phosphorylation ( OXPHOS ), decreases mitochondrial membrane potential (MMP) and induces apoptosis in embryonic cell. BDE 47 induces the generation of ROS , and activates the JNK signaling pathway. BDE 47 exhibits embryonic developmental toxicity in zebrafish [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5436-43-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-W762011. | |
| BDP 558/568 NHS ester | BDP 558/568 NHS ester is a borondipyrromethene fluorophore with emission in the yellow part of the spectrum. BDP 558/568 NHS ester is an amine reactive NHS ester, and the absorption and emission spectra of BDP 558/568 NHS ester are similar with TAMRA, BDP TMR, Cyanine3, and sulfo-Cyanine3 [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: BODIPY 558/568SE. CAS No. 150173-73-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1662. | |
| BDP 581/591 NHS ester | BDP 581/591 NHS ester is a a borondipyrromethene dye (Ex=585 nm, Em=594 nm) that has relatively long fluorescence lifetime and two photon excitation cross section. BDP 581/591 NHS ester can be used for fluorescence polarization analysis and also reacts with reactive oxygen species (ROS) and alter fluorescence. BDP 581/591 NHS ester is also an NHS ester derivative that can be used to bind primary and secondary amine groups of proteins, peptides and other molecules. Uses: Scientific research. Group: Fluorescent dye. CAS No. 654651-21-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1653. | |
| BDP FL amine hydrochloride | BDP FL amine hydrochloride is a borondipyrromethene dye with good water solubility. BDP FL amine hydrochloride can be read on the FAM channel [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2183473-03-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-D1368. | |
| BDP R6G NHS ester | CellTracker Green BODIPY (compound 31) is a green fluorescent dye that acts as an intracellular environmental tracer [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1443457-59-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D1906. | |
| BDP TMR NHS ester | BDP TMR NHS ester is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. Uses: Scientific research. Group: Fluorescent dye. CAS No. 485397-12-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-D1232. | |
| BDTX-1535 | BDTX-1535 (EGFR-IN-76, compound 37A) is an orally active, brain-penetrant, selective and potent EGFR tyrosine kinase inhibitor. BDTX-1535 achieves potent anti-tumor activity against EGFR alterations and amplification across models including NSCLC, GBM PDX and intracranial tumors [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EGFR-IN-76. CAS No. 2607829-38-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153268. | |
| Beauvericin | Beauvericin is a cyclohexapeptide Fusarium toxin with insecticidal, antibacterial, anticancer, antiviral and cytotoxic activities. Beauvericin causes cellular genotoxicity by producing DNA breaks, chromosomal aberrations and micronuclei, and inhibits the PI3K/AKT pathway to induce apoptosis , thereby inhibiting the growth of HCC. In addition, Beauvericin affects immune function by inhibiting lymphocyte proliferation and interfering with the differentiation process of human monocytes into macrophages [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Natural products. CAS No. 26048-05-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N6739. | |
| Bebtelovimab | Bebtelovimab a humanized IgG1-λ2 antibody targeting to SARS-CoV-2 , especially COVID-19. Bebtelovimab potently neutralizes SARS-CoV-2 variants, and inhibits COVID-19 with mild-to-moderate efficacy [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY-3853113; LY-COV1404. CAS No. 2578319-11-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99103. | |
| BEC hydrochloride | BEC hydrochloride is a slow-binding and competitive Arginase II inhibitor with K i of 0.31 μM and 30 nM at pH 7.5 and pH 9.5, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 222638-67-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19548A. | |
| Beclabuvir | Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus ( HCV ) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC 50 of < 28 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-791325. CAS No. 958002-33-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12429. | |
| Beclamide | Beclamide is an active molecule with anticonvulsant activity, used as an anticonvulsant drug. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Benzyl-3-chloropropionamide. CAS No. 501-68-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1185. | |
| Beclometasone | Beclometasone (Beclomethasone) is a prototype glucocorticoid receptor agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Beclomethasone. CAS No. 4419-39-0. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B1540. | |
| Beclometasone dipropionate | Beclometasone dipropionate, the proagent of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate can be used for asthma [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Beclomethasone dipropionate. CAS No. 5534-9-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-13571A. | |
| Beclometasone dipropionate (Standard) | Beclometasone dipropionate (Standard) is the analytical standard of Beclometasone dipropionate. This product is intended for research and analytical applications. Beclometasone dipropionate, the proagent of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate can be used for asthma [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Beclomethasone dipropionate (Standard). CAS No. 5534-9-8. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-13571AR. | |
| Becotatug | Becotatug (JMT-101) is an IgG1 antibody targeting EGFR that can also be conjugated to Afatinib (HY-10261) and Osimertinib (HY-15772) as a synthetic ADC [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: JMT-101. CAS No. 2648260-93-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990049. | |
| Bedaquiline | Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit [1]. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TMC207; R207910. CAS No. 843663-66-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14881. | |
| Bedaquiline fumarate | Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R403323; TMC207 fumarate; R207910 fumarate. CAS No. 845533-86-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14881A. | |
| Bedinvetmab | Bedinvetmab (ZTS-00508841) is a canine monoclonal antibody (mAb) targeting nerve growth factor (NGF). Bedinvetmab inhibits NGF interaction with tropomyosin receptor kinase A (trkA) and p75 neurotrophin receptor (p75NTR) receptors. Bedinvetmab can be used for the research of osteoarthritis pain in dogs [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ZTS-00508841. CAS No. 2171034-69-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99297. | |
| Beef extract | Beef extract is a common ingredient in the preparation of biological culture media [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 68990-09-0. Pack Sizes: 250 g. Product ID: HY-156261. | |
| Beeswax | Beeswax is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 8012-89-3. Pack Sizes: 1 g; 5 g. Product ID: HY-W133974. | |
| Befiradol | Befiradol (NLX-112) is a selective 5-HT1A receptor agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NLX-112; F13640. CAS No. 208110-64-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14785. | |
| Befiradol hydrochloride | Befiradol hydrochloride (NLX-112 hydrochloride) is a selective 5-HT 1A receptor agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NLX-112 hydrochloride; F 13640 hydrochloride. CAS No. 2436760-81-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14785A. | |
| Befotertinib | Befotertinib (D-0316) is the third-generation EGFR tyrosine kinase inhibitor. Befotertinib can be used for the research of EGFR T790M-positive non-small cell lung cancer (NSCLC) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-0316. CAS No. 1835667-63-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137433. | |
| Begacestat | Begacestat (GSI-953) is a selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase (IC 50 Aβ 40 =15 nM) for the treatment of Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSI-953. CAS No. 769169-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14175. | |
| Begelomab | Begelomab (SAND-26) is a murine IgG2b monoclonal antibody against DPP-4/CD26. Begelomab can be used for the research of severe refractory idiopathic inflammatory myopathy [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SAND-26. CAS No. 1403744-56-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99466. | |
| Behenamide | Behenamide is a fatty acid derived from plants such as rapeseed oil and can be synthesized by a variety of processes. Behenamide has unique properties that make it useful as a slip agent, A lubricant and release agent, it is also used in personal care products, including cosmetics and hair care, as a thickener and emollient because of its ability to improve the consistency and texture of formulations. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Docosanamide. CAS No. 3061-75-4. Pack Sizes: 1 g; 5 g. Product ID: HY-W127445. | |
| Bekanamycin | Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus , against an array of Gram-positive and Gram-negative bacterial strain [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Kanamycin B. CAS No. 4696-76-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1174. | |
| BeKm-1 | BeKm-1 is a HERG (human ether-a-go-go-related gene) blocking compound. BeKm-1 can be used for the research of heart disease [1]. Uses: Scientific research. Group: Peptides. CAS No. 524962-01-4. Pack Sizes: 100 μg; 500 μg; 1 mg; 5 mg. Product ID: HY-P1440. | |
| Belantamab | Belantamab (GSK2857916) is a humanized IgG1 anti-BCMA/TNFRSF17 monoclonal antibody. Belantamab is linked to MMAF (HY-15579) through a non-cleavable ADC linker to synthesize the antibody-active molecule conjugate (ADC) Belantamab mafodotin (HY-P3239). After binding to BCMA on the surface of tumor cells, Belantamab mafodotin enters the cell through receptor-mediated endocytosis. After entering the cell, Belantamab mafodotin releases MMAF, blocks cell division by inhibiting tubulin polymerization, arrests the cell cycle and induces cell apoptosis. Belantamab can be used for the study of multiple myeloma, especially relapsed/refractory multiple myeloma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GSK2857914. CAS No. 2061894-48-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9980. | |
| Belantamab mafodotin | Belantamab mafodotin (GSK2857916) is composed of humanized and focused monoclonal antibody against B cell maturation antigen (BCMA) and McMMAF. Belantamab mafodotin has anti-myeloma activity [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GSK2857916; Belantamab mafodotin-blm. CAS No. 2050232-20-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3239. | |
| Belapectin | Belapectin (GR-MD-02) is a Galectin-3 (Gal-3) inhibitor. Belapectin drives tumor-induced immunosuppression by inducing T cell Apoptosis. Belapectin promotes tumor regression and improves survival of tumor-bearing mice through a CD8+ T cell-dependent mechanism. Belapectin binds to Gal-3 with affinity K i of 2.8 μM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR-MD-02. CAS No. 1980787-47-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-114440. | |
| Belatacept | Belatacept (BMS 224818) is a selective T-cell costimulation blocker and a costimulator of the CD28-CD80/86 pathway. Belatacept binds to the CD 80/86 ligand and inhibits CD-28-mediated T cell costimulation and IFN-γ production. Belatacept can be used in studies of immunosuppression in organ transplantation [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS 224818; LEA 29Y. CAS No. 706808-37-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-108813. | |
| Belimumab | Belimumab (LymphoStat B) is a humanized IgG1λ monoclonal antibody against B-lymphocyte stimulator ( BLyS ) protein. Belimumab antagonizes BLyS activity in autoimmune diseases and B-lymphocyte malignancies. Belimumab can be used for systemic lupus erythematosus (SLE) research [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LymphoStat B. CAS No. 356547-88-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P9952. | |
| Belinostat | Belinostat (PXD101; PX105684) is a potent HDAC inhibitor with an IC 50 of 27 nM in HeLa cell extracts. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PXD101; PX105684. CAS No. 866323-14-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10225. | |
| Beloranib | Beloranib is a fumagillin-class methionine aminopetidase-2 (MetAP2) inhibitor. Beloranib decreases food intake, body weight, fat mass, and the size of adipocytes [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZGN-440; CKD-732 free base. CAS No. 251111-30-5. Pack Sizes: 1 mg. Product ID: HY-14811. | |
| Belotecan | Belotecan (CKD-602 free base) is a DNA topoisomerase I inhibitor. Belotecan induces cell apoptosis and cell-cycle arrest. Belotecan is a camptothecin analogue with anti-tumor effects, it can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CKD-602 free base. CAS No. 256411-32-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13566. | |
| Belotecan hydrochloride | Belotecan hydrochloride (CKD-602 hydrochloride), a Topoisomerase I inhibitor, is a synthetic camptothecin derivative. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CKD-602. CAS No. 213819-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13566A. | |
| Belrestotug | Belrestotug (EOS-448) is an antagonistic anti- TIGIT (VSIG9, VSTM3) human immunoglobulin G1 kappa (hIgG1 kappa) antibody. Belrestotug shows antineoplastic activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: EOS-448; EOS884448; GSK4428859A. CAS No. 2574438-65-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990032. | |
| Belumosudil | Belumosudil (KD025) is a selective inhibitor of ROCK2 with IC 50 s of 105 nM and 24 μM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KD025; SLx-2119. CAS No. 911417-87-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15307. | |
| Belumosudil mesylate | Belumosudil mesylate (KD025 mesylate) is a selective inhibitor of ROCK2 with IC 50 s of 105 nM and 24 μM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KD025 mesylate; SLx-2119 mesylate. CAS No. 2109704-99-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15307A. | |
| Belvarafenib | Belvarafenib (HM95573) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC 50 s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAF v600E and C-RAF respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HM95573; GDC-5573; RG6185. CAS No. 1446113-23-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109080. | |
| Belzutifan | Belzutifan (PT2977) is an orally active and selective HIF-2α inhibitor with an IC 50 of 9 nM. Belzutifan, as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile. Belzutifan is a potential treatment for clear cell renal cell carcinoma (ccRCC) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PT2977; MK-6482. CAS No. 1672668-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125840. | |
| Bemarituzumab | Bemarituzumab is a first-in-class, humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has the potential for cancer research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1952272-74-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99010. | |
| Bemcentinib | Bemcentinib (R428) is a potent and selective inhibitor of Axl with an IC 50 of 14 nM [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R428; BGB324. CAS No. 1037624-75-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15150. | |
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