MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Cosfroviximab | Cosfroviximab (c13C6-FR1) is a mouse/human chimeric monoclonal antibody against Ebola virus glycoprotein (EBOV-GP) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: c13C6-FR1. CAS No. 1792982-57-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99832. |  |
| Cosibelimab | Cosibelimab (CK-301; TG-1501) is a high-affinity, fully human PD-L1 -blocking monoclonal antibody that binds PD-L1 and blocks its interaction with PD-1. Cosibelimab has a functional Fc domain and is capable of inducing ADCC and complement-dependent cytotoxicity (CDC)-mediated killing of PD-L1 + cell lines, including lymphoma cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CK-301; TG-1501. CAS No. 2216751-26-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99833. | |
| Costunolide | Costunolide ((+)-Costunolide) is a naturally occurring sesquiterpene lactone, with antioxidative, anti-inflammatory, antiallergic, bone remodeling, neuroprotective, hair growth promoting, anticancer, and antidiabetic properties. Costunolide can induce cell cycle arrest and apoptosis on breast cancer cells [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Costunolide; Costus lactone. CAS No. 553-21-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0036. | |
| Cotadutide | Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC 50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D) [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: MEDI0382. CAS No. 1686108-82-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2231. | |
| Cotinine | Cotinine ((-)-Cotinine) is an orally active alkaloid found in tobacco and is the primary metabolite of nicotine. Cotinine is metabolized by CYP2A13 into trans-3'-hydroxycotinine. Cotinine is used as a biomarker to measure exposure to tobacco smoke components. Cotinine has vasodepressor activity. The mixture of cotinine and nicotine (Nicotine) has antiproliferative activity against pterygium. (S)-(-)-Cotinine activates nicotinic acetylcholine receptors ( nAChR ) in a calcium-dependent manner, leading to the release of dopamine (Dopamine, HY-B0451). Cotinine ((-)-Cotinine) is used in research related to cardiovascular and inflammatory diseases [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Cotinine; (S)-Cotinine; NIH-10498. CAS No. 486-56-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B1178. | |
| Cottonseed oil | Cottonseed oil is a cooking oil extracted from the seeds of cotton plants and has been generally considered the most insecticidal of vegetable oils. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 8001-29-4. Pack Sizes: 100 mL; 500 mL. Product ID: HY-Y1887. | |
| Coumarin | Coumarin is a potent and orally active anti-inflammatory agent. Coumarin shows an antinociceptive effect. Coumarin shows antibacterial, antifungal and anticancer activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 91-64-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0709. | |
| Coumarin 106 | Coumarin 106 (Coumarin 478) is a dipolar laser dye. Coumarin 106 is an inhibitor of AChE and BChE. Coumarin 106 displays mixed-type AChE inhibition with a pIC 50 =4.97 and K i =2.36 μM. Coumarin 106 inhibits BChE with slightly lower potency ( pIC 50 =4.56) [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Coumarin 478. CAS No. 41175-45-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W324391. | |
| Coumarin 343 | Coumarin 343 (C343) is a hydrophilic fluorescent probe for the micro water pool. λem is approximately 425 nm andλem is approximately from 425 nm to 550 nm by RF-1500 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C343. CAS No. 55804-65-4. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W267364. | |
| Coumarin-3-carboxylic Acid | Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Oxochromene-3-carboxylic acid. CAS No. 531-81-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W027968. | |
| Coumarin 6 | Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λ exc =450 nm, λ em =505 nm) [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 38215-36-0. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-N7131. | |
| Coumestrol | Coumestrol, a phytoestrogen present in soybean products, exhibits activities against cancers, neurological disorders, and autoimmune diseases. It suppresses proliferation of ES2 cells with an IC 50 of 50 μM. Uses: Scientific research. Group: Natural products. CAS No. 479-13-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2335. | |
| COX-2-IN-18 | COX-2-IN-18 (Compound 3) is a potent inhibitor of COX-2. COX-2-IN-18 possesses good COX-2 inhibitory activity ( IC 50 = 0.775 μM) compared to the reference agent, Celecoxib ( IC 50 = 0.153 μM). COX-2-IN-18 has the potential for the research of cancer diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1038061-96-9. Pack Sizes: 5 mg. Product ID: HY-147794. | |
| CP-10 | CP-10 is a PROTAC connected by ligands for Cereblon and CDK , with highly selective, specific, and remarkable CDK6 degradation ( DC 50 =2.1 nM). It inhibits proliferation of several haematopoietic cancer cells with impressive potency including multiple myeloma, and can still degrades mutated and overexpressed CDK6 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2366268-80-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-125835. | |
| CP 154526 hydrochloride | CP 154526 hydrochloride is a potent, brain-penetrant and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist with a K i of 2.7 nM. CP 154526 hydrochloride shows selective for CRF1 over CRF2 (K i=>10 μM). CP 154526 hydrochloride has anxiolytic activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 257639-98-8. Pack Sizes: 5 mg. Product ID: HY-12129. | |
| CP26 | CP26 is a small molecule inhibitor of protein dislocation from the ER lumen to the cytosol. CP26 targets the Hrd1 complex, inhibits ERAD, and induces ER stress [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 500285-30-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-49116. | |
| CP-31398 dihydrochloride | CP-31398 dihydrochloride stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1217195-61-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18343A. | |
| CP 339818 hydrochloride | CP 339818 hydrochloride is a nonpeptide and selective Kv1.3 ( IC 50 value of ~200 nM) and Kv1.4 channels blocker. CP 339818 hydrochloride is a significantly less potent blocker of Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2. CP 339818 hydrochloride potently blocks the C-type inactivated conformation of Kv1.3 and suppresses T cell activation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 478341-55-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108574. | |
| CP-465022 | CP-465022 is a potent, and selective noncompetitive AMPA receptor antagonist with anticonvulsant activity. CP-465022 is against Kainate-induced response with an IC 50 of 25 nM in rat cortical neurons. CP-465022 provides a new tool to investigate the role of AMPA receptors in physiological and pathophysiological processes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199655-36-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18663. | |
| CP-640186 | CP-640186 is an orally active and cell-permeable Acetyl-CoA carboxylase ( ACC ) inhibitor with IC 50 s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 can also stimulate muscle fatty acid oxidation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 591778-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15259. | |
| CP-640186 hydrochloride | CP-640186 hydrochloride is an orally active and cell-permeable Acetyl-CoA carboxylase ( ACC ) inhibitor with IC 50 s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 hydrochloride can also stimulate muscle fatty acid oxidation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 591778-70-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15259A. | |
| CP-724714 | CP-724714 is a potent, selective and orally active ErbB2 (HER2) tyrosine kinase inhibitor, with an IC 50 of 10 nM. CP-724714 displays a marked selectivity against EGFR kinase (IC 50 =6400 nM). CP-724714 potently inhibits ErbB2 receptor autophosphorylation in intact cells. Antitumor activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 383432-38-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14674. | |
| CP-775146 | CP-775146 is a selective PPARα agonist that binds strongly to the PPARα ligand. CP-775146 efficiently alleviates obesity-induced liver damage, prevents lipid accumulation by activating the liver fatty acid β-oxidation pathway [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 702680-17-9. Pack Sizes: 5 mg. Product ID: HY-108571. | |
| CP-809101 hydrochloride | CP-809101 hydrochloride is a potent and highly selective 5-HT 2C receptor agonist, with pEC 50 s of 9.96, 7.19 and 6.81 M for human 5HT 2C , 5HT 2B and 5HT 2A receptor. CP-809101 hydrochloride inhibits conditioned avoidance responding in rats and antagonizes both PCP (phencyclidine hydrochloride)- and d-amphetamine-induced hyperactivity. CP-809101 hydrochloride also reduces food and nicotine dependence in rats, can be used in studies of antipsychotic and nicotine dependence [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1215721-40-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15543A. | |
| CP-91149 | CP-91149 is a GP (glycogen phosphorylase) inhibitor. CP-91149 promotes glycogen resynthesis, but not its overaccumulation. CP-91149 has the potential for Type II (insulin-dependent) diabetes study [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 186392-40-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13525. | |
| CP 93129 dihydrochloride | CP 93129 dihydrochloride is a potent 5HT 1B receptor agonist. CP 93129 dihydrochloride has the potential for parkinson's disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 879089-64-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101357A. | |
| CP94253 hydrochloride | CP94253 hydrochloride is a potent and selective agonist of 5-HT 1B receptor ( K i = 2 nM in a radioligand binding assay).K i values for 5-HT 1A , 5-HT 1D , 5-HT 1C and 5-HT 2 receptors are 89, 49, 860, and 1600 nM respectively [1]. CP94253 hydrochloride is centrally active upon systemic administration in vivo [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 845861-39-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103151. | |
| CPCCOEt | CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of metabotropic glutamate receptor 1b (mGluR1b) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179067-99-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101356. | |
| CPDA | CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1415834-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18685. | |
| C-Peptide 1 (rat) | C-Peptide 1 (rat), a peptide, is aβ-catenin/GSK-3β activator. C-Peptide 1 (rat) can regulate the Wnt/β-catenin signaling pathway. C-Peptide 1 (rat) can be used for the research of cancer [1]. Uses: Scientific research. Group: Peptides. CAS No. 41475-27-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4858. | |
| C-Phycocyanin | C-phycocyanin (C-PC) is a protein pigment which is also widely used as an excellent nutrient supplement for human beings. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: C-PC. CAS No. 11016-15-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1025. | |
| CPI-455 | CPI-455 is a specific, pan- KDM5 inhibitor with an IC 50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1628208-23-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100421. | |
| CPK20 | CPK20 is a potent and highly selective KCNT1 channel blocker, and CPK20 can be used in the study of epilepsy [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2397708-22-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162549. | |
| CPM | CPM is a maleimide derivative, acting as a blue fluorescent thiol-reactive dye (excitation/emission maxima of 387/463 nm) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 76877-33-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D0069. | |
| CPPG | CPPG ((RS)-CPPG) is a potent group II/III mGlu receptors antagonist. CPPG exhibits some selectivity (approximately 20 fold) for group III ( IC 50 =2.2 nM) over group II ( IC 50 =46.2 nM) mGlu receptors in the rat cerebral cortex. CPPG has weak effects at group I mGlu receptors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (RS)-CPPG. CAS No. 183364-82-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101333. | |
| CPS-11 | CPS-11 (N-(Hydroxymethyl)thalidomide) a Thalidomide (HY-14658) analogue, is a potent anti-cancer agent. CPS-11 inhibits NF-κB , activates NFAT , and repress cytokine expression through elevated ROS. CPS-11 exhibits a wider activity spectrum and higher potency against MM (multiple myeloma) cell lines [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-(Hydroxymethyl)thalidomide. CAS No. 145945-21-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-117987. | |
| CPS2 | CPS2 is a first-in-class, highly potent, selective and irreversible PROTAC CDK2 degrader ( IC 50 = 24 nM). CPS2 can be used for the research of acute myeloid leukemia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2756741-90-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141680. | |
| CRAMP (mouse) | CRAMP (mouse) is an antimicrobial peptide. CRAMP (mouse) can be used for the research of biofilm-associated infections [1]. Uses: Scientific research. Group: Peptides. CAS No. 376364-36-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4855. | |
| CRANAD-2 | CRANAD-2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a K d of 38 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1193447-34-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-103242. | |
| Creatinase, microorganism | Creatine amidinohydrolase, microorganism is a hydrolytic enzyme that catalyzes the hydrolysis of creatine into creatinine and urea, playing a crucial role in the measurement of creatinine concentration. Creatine amidinohydrolase, microorganism can be used in the development of biosensors for measuring serum creatinine levels [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Creatine amidinohydrolase, microorganism. CAS No. 37340-58-2. Pack Sizes: 1 KU; 5 KU. Product ID: HY-P2893B. | |
| Creatine | Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain. Uses: Scientific research. Group: Natural products. CAS No. 57-00-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-W010388. | |
| Creatine monohydrate | Creatine monohydrate, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain [1]. Uses: Scientific research. Group: Natural products. CAS No. 6020-87-7. Pack Sizes: 100 mg. Product ID: HY-W017462. | |
| Creatininase, Microorganism | Creatininase, Microorganism (Creatinine amidohydrolase; CAH), namely creatinine amidohydrolase, from Pseudomonas putida , is a homohexameric enzyme commonly used in biochemical research. Creatininase acts on carbon-nitrogen bonds other than peptide bonds, and can catalyze the hydrolysis of creatinine to creatine, which can then be metabolized by creatinase to urea and sarcosine [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Creatinine amidohydrolase; CAH. CAS No. 9025-13-2. Pack Sizes: 1 KU. Product ID: HY-P2838. | |
| Creatinine | Creatinine (NSC13123) is a breakdown product of creatine phosphate in muscles. Uses: Scientific research. Group: Natural products. Alternative Names: NSC13123. CAS No. 60-27-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0504. | |
| Creatinine-d3 | Creatinine-d 3 is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle [1]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC13123-d3. CAS No. 143827-20-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0504S. | |
| Creatinine (Standard) | Creatinine (Standard) is the analytical standard of Creatinine. This product is intended for research and analytical applications. Creatinine (NSC13123) is a breakdown product of creatine phosphate in muscles. Uses: Scientific research. Group: Natural products. CAS No. 60-27-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0504R. | |
| Crebanine | Crebanine, an alkaloid from Stephania venosa , induces G1 arrest and apoptosis in human cancer cells. Crebanine exhibits anti-inflammatory activity via suppressing MAPKs and Akt signaling. Crebanine also possesses antiarrhythmic effect [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 25127-29-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N2255. | |
| Crelosidenib | Mutant IDH1-IN-6 is a potent, selective and orally active mutant isocitrate dehydrogenase (IDH) inhibitor with IC 50 s of 6.27 nM, 3.71 nM, 36.9 nM and 11.5 nM for IDH1 R132H , IDH1 R132C , IDH2 R140Q and IDH2 R172K mutant enzymes , respectively. Mutant IDH1-IN-6 is less active at inhibiting the IDH wild-type enzymes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY3410738; Mutant IDH1-IN-6. CAS No. 2230263-60-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-131312. | |
| Crenezumab | Crenezumab (MABT 5102A; RG 7412) is a fully humanized anti-Aβ monoclonal antibody that binds multiple forms of Aβ, such as soluble, oligomeric and fibrillar, for use in Alzheimer's disease research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MABT 5102A; RG 7412. CAS No. 1095207-05-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99835. | |
| Crenigacestat | Crenigacestat (LY3039478) is an orally active Notch and γ-secretase inhibitor, with an IC 50 of 1 nM in most of the tumor cell lines tested [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY3039478. CAS No. 1421438-81-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12449. | |
| Crenolanib | Crenolanib is a potent and selective inhibitor of wild-type and mutant isoforms of the class III receptor tyrosine kinases FLT3 and PDGFRα/β with K d s of 0.74 nM and 2.1 nM/3.2 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-868596. CAS No. 670220-88-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13223. | |
| Creosol | Creosol (2-Methoxy-4-methylphenol) is an endogenous metabolite that acts as an important chemical intermediate and potential biofuel mainly derived from lignocellulosic biomass. Creosol is blood brain barrier penetrable [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Methoxy-4-methylphenol. CAS No. 93-51-6. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W040971. | |
| Cresyl Violet acetate | Cresyl Violet acetate is a dye, which can be used to stain neurons. Uses: Scientific research. Group: Fluorescent dye. CAS No. 10510-54-0. Pack Sizes: 100 mg. Product ID: HY-101888. | |
| Crinecerfont hydrochloride | Crinecerfont (SSR-125543) hydrochloride is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research [1]. Crinecerfont (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SSR-125543 hydrochloride. CAS No. 321839-75-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-106203A. | |
| Crisaborole | Crisaborole (AN-2728) is a potent inhibitor of PDE4 and cytokine release; inhibit PDE4 with an IC 50 of 0.49 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AN-2728; PF-06930164. CAS No. 906673-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10978. | |
| Crisaborole (Standard) | Crisaborole (Standard) is the analytical standard of Crisaborole. This product is intended for research and analytical applications. Crisaborole (AN-2728) is a potent inhibitor of PDE4 and cytokine release; inhibit PDE4 with an IC 50 of 0.49 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 906673-24-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10978R. | |
| Crisdesalazine | Crisdesalazine (AAD-2004) is an anti-inflammatory agent that simultaneously blocks inflammation mediated by free radicals and prostaglandin E2 (PGE2). Crisdesalazine (AAD-2004) can be used to study neurodegeneration in amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AAD-2004. CAS No. 927685-43-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-105005. | |
| Crizanlizumab | Crizanlizumab is an anti- P-selectin monoclonal antibody. Crizanlizumab binds to P-selectin and blocks its interaction with P-selectin glycoprotein ligand 1 (PSGL-1). Crizanlizumab prevents vaso-occlusive crises (VOCs) and can be used for research of sickle cell disease [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1690318-25-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9987. | |
| Crizotinib | Crizotinib (PF-02341066) is an orally bioavailable, ATP-competitive ALK and c-Met inhibitor with IC 50 s of 20 and 8 nM, respectively. Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC 50 s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth inhibition [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-02341066. CAS No. 877399-52-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-50878. | |
| Crizotinib hydrochloride | Crizotinib hydrochloride (PF-02341066 hydrochloride) is an orally bioavailable, selective, and ATP-competitive dual ALK and c-Met inhibitor with IC 50 s of 20 and 8 nM, respectively. Crizotinib hydrochloride (PF-02341066 hydrochloride) inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC 50 s of 24 and 11 nM in cell-based assays, respectively. It is also a ROS proto-oncogene 1 (ROS1) inhibitor. Crizotinib hydrochloride (PF-02341066 hydrochloride) has effective tumor growth inhibition [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-02341066 hydrochloride. CAS No. 1415560-69-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-50878A. | |
| Crocetin | Crocetin (Transcrocetin), extracted from saffron ( Crocus sativus L. ), acts as an NMDA receptor antagonist with high affinity [1]. Crocetin is capable of crossing the blood-brain barrier and reach the central nervous system (CNS) [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Transcrocetin; trans-Crocetin. CAS No. 27876-94-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2072. | |
| Crocin | Crocin (Crocin I) is an orally active natural product that can be isolated from the stigma of Crocus sativus. Crocin inhibits tumor cell proliferation and promotes apoptosis through JAK pathway. Crocin has anti-inflammatory, antioxidant and antitumor activities [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Crocin I. CAS No. 42553-65-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0697. | |
| Crocin II | Crocin II is isolated from the fruit of Gardenia jasminoides with antioxidant, anticancer, and antidepressant activity. Crocin II inhibits NO production with an IC 50 value of 31.1 μM. Crocin II suppresses the expressions of protein and m-RNA of iNOS and COX-2 [1]. Uses: Scientific research. Group: Natural products. CAS No. 55750-84-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0698. | |
| Croconic acid disodium | Croconic acid (disodium) (Nacr) can promote cell growth and proliferation by enhancing the expression of genes associated with lysine crotonylation (Kcr) modification. Croconic acid holds potential for improving somatic cell nuclear transfer (SCNT) efficiency and optimizing cell culture conditions research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nacr. CAS No. 14379-00-1. Pack Sizes: 50 mg. Product ID: HY-W105310A. | |
| Cromakalim | Cromakalim is a potassium channel opener. Cromakalim can be used as a bronchodilator in asthma. Cromakalim inhibits the spontaneous tone of human isolated bronchi in a concentration-related manner being nearly as effective as isoprenaline or theophylline [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL 34915. CAS No. 94470-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110011. | |
| Cromolyn | Cromolyn is a mast cell stabilizer. Cromolyn has the potential for the research of bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cromoglicic acid. CAS No. 16110-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1619. | |
| Cromolyn sodium | Cromolyn sodium (Disodium Cromoglycate; FPL-670) is an antiallergic agent. Cromolyn sodium is a GSK-3β inhibitor with an IC 50 of 2.0 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Disodium Cromoglycate; FPL-670. CAS No. 15826-37-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0320A. | |
| Cross-linked dextran G 25 | Cross-linked dextran G 25 is a dextran chromatography medium. Cross-linked dextran G 25 separates from 1 to 5 kD (spherical proteins) and can be used for the separation of peptides as well as for the desalting and buffer replacement of large molecule proteins [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9041-35-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-148140. | |
| Crosstide | Crosstide is a peptide analog of glycogen synthase kinase α/β fusion protein sequence which is a substrate for Akt. Uses: Scientific research. Group: Peptides. CAS No. 171783-05-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0315. | |
| Crotamiton | Crotamiton is a drug that is used both as a scabicidal (for treating scabies) and as a general antipruritic. Uses: Scientific research. Group: Signaling pathways. CAS No. 483-63-6. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1177. | |
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