MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Crotonaldehyde 2,4-dinitrophenylhydrazone-d3 | Crotonaldehyde 2,4-dinitrophenylhydrazone-d 3 is the deuterium labeled Crotonaldehyde 2,4-dinitrophenylhydrazone[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 259824-64-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W013388S. |  |
| Crovalimab | Crovalimab (SKY59; RO7112689) is a novel humanized antibody against C5 in a pH-dependent manner with KDs of 15.2?nM and 16.8 μM at pH 7.4 and 5.8, respectively. Crovalimab binds human FcRn with great affinity (KD: 17 μM at pH 6.0). Crovalimab can block cleavage of C5 by the C5 convertase and inhibite the activity of a C5 variant (p.Arg885His). Crovalimab inhibits C5b-9 formation significantly in all three complement pathways, the classical pathway (CP), lectin pathway (LP), and alternative pathway (AP). Crovalimab has the potential for paroxysmal nocturnal hemoglobinuria (PNH) and complement-mediated diseases research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SKY59; RO7112689. CAS No. 1917321-26-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99965. | |
| Crozbaciclib | Crozbaciclib (CDK4/6/1 Inhibitor) is a CDK4/6 inhibitor with IC 50 s of 3 and 1 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDK4/6/1 Inhibitor. CAS No. 2099128-41-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-112280. | |
| Crozbaciclib fumarate | Crozbaciclib fumarate is a CDK4/6 inhibitor with IC 50 s of 3 and 1 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 2567494-39-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-112280A. | |
| CRT | CRT, an iron peptide mimic, can bind to apo-transferrin ( apo-Tf ). CRT can be used to modify nanoparticles, and enhances drug delivery efficiency [1]. Uses: Scientific research. Group: Peptides. CAS No. 2414254-70-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5533. | |
| CRT0066101 | CRT0066101 is a potent and orally active PKD inhibitor with IC 50 values of 1 nM, 2.5 nM and 2 nM for PKD1 , PKD2 , and PKD3 , respectively [1]. CRT0066101 is also a potent PIM2 inhibitor with an IC 50 of ~135.7?nM. CRT0066101 exhibits anti-inflammatory activity in mice LPS (HY-D1056)-induced lung injury models, and has anticancer effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 956123-34-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-15698. | |
| CRT0066101 dihydrochloride | CRT0066101 dihydrochloride is a potent and orally active PKD inhibitor with IC 50 values of 1 nM, 2.5 nM and 2 nM for PKD1 , PKD2 , and PKD3 , respectively [1]. CRT0066101 dihydrochloride is also a potent PIM2 inhibitor with an IC 50 of ~135.7?nM. CRT0066101 dihydrochloride exhibits anti-inflammatory activity in mice LPS (HY-D1056)-induced lung injury models, and has anticancer effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1883545-60-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15698A. | |
| CRT0066854 | CRT0066854 is a potent and selective atypical PKC isoenzymes inhibitor. CRT0066854 is against full-length (FL) PKCΙ , PKCζ , and ROCK-II kinases with IC 50 values of 132 nM, 639 nM, and 620 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1438881-19-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18713. | |
| CRT0066854 hydrochloride | CRT0066854 hydrochloride is a potent and selective atypical PKC s inhibitor. CRT0066854 is against full-length (FL) PKCΙ , PKCζ , and ROCK-II kinases with IC 50 values of 132 nM, 639 nM, and 620 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2250019-91-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-18713A. | |
| (-)-Cryptopleurine | ( - )-Cryptopleurine is an alkaloid that has been found in Lauraceae and has diverse biological activities. It inhibits the growth of human A375 melanoma, A431 epidermoid carcinoma, A549 lung, MES-SA uterine sarcoma, and MCF-7 breast cancer cells ( IC 50 =3 nM for all).2 ( - )-Cryptopleurine inhibits hypoxia-induced gene expression in a hypoxia response element (HRE) reporter assay ( IC 50 =8.7 nM).3 ( - )-Cryptopleurine (500 μg/mL) prevents lesion formation in tobacco (N. tabacum) plants infected with tobacco mosaic virus (TMV). It also inhibits protein synthesis by yeast and mammalian ribosomes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Cryptopleurine; NSC 19912. CAS No. 482-22-4. Pack Sizes: 1 mg. Product ID: HY-121255. | |
| Cryptotanshinone | Cryptotanshinone is a natural compound extracted from the root of Salvia miltiorrhiza Bunge that shows antitumor activities. Cryptotanshinone inhibits STAT3 with an IC 50 of 4.6 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Cryptotanshinon; Tanshinone c. CAS No. 35825-57-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0174. | |
| Crystal Ponceau 6R | Crystal Ponceau 6R is a red azo dye. Crystal Ponceau 6R used in histology, for staining fibrin with the martius, scarlet and blue (MSB) Trichrome stain [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2766-77-0. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-D1480. | |
| Crystal Violet | Crystal Violet, also known as Gentian violet, methyl violet 10B, is a triphenyl-methane, an alkaline dye that binds to DNA in the nucleus of a cell, staining it a deep purple. It is often used for Gram staining to classify bacteria, or for cell or histological staining[1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Basic Violet 3; Gentian Violet; Methyl Violet 10B. CAS No. 548-62-9. Pack Sizes: 500 mg; 5 g; 10 g. Product ID: HY-B0324A. | |
| CS-2100 | CS-2100 (Compound 10b) is a potent, selective, orally active and S1P 3 -sparing S1P 1 agonist with an EC 50 of 4.0 nM for human S1P 1. CS-2100 shows in vivo immunosuppressive efficacy in rats with an ID 50 (infective dose) of 0.407 mg/kg for HvGR [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 913827-99-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108493. | |
| CSF1R-IN-24 | CSF1R-IN-24 (Example 134) is an orally active CSF1R inhibitor. CSF1R-IN-24 significantly inhibits the survival of human ipSC-derived microglia (hiPSC-MG) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3024322-57-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160842. | |
| CSF1R-IN-3 | CSF1R-IN-3 (compound 21) is a potent and orally active CSF-1R inhibitor ( IC 50 =2.1 nM). CSF1R-IN-3 is a potent antiproliferative activity against colorectal cancer cells. CSF1R-IN-3 inhibits the progression of colorectal cancer by suppressing the migration of macrophages, reprograming M2-like macrophages to the M1 phenotype, and enhancing the antitumor immunity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2760584-90-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139990. | |
| CSP1 | CSP1 is a potent and selective ComD1 receptor agonist, with an IC 50 of 10.3 nM. CSP1 is a major variants of competence-stimulating peptide (CSP), and it can regulate genetic transformation of S. pneumonia by modulating quorum sensing (QS). CSP1 can act as an antibacterial agent [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 172889-49-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2454. | |
| CST626 | CST626 (Compound 9) is a pan- IAP degrader PROTAC. CST626 degrades XIAP, cIAP1 and cIAP2 with DC 50 s of 0.7, 2.4, and 6.2 nM in MM.1S cells, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3033993-13-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-149924. | |
| CT1812 | CT1812 (Sigma-2 receptor antagonist 1) is an orally active and brain penetrant sigma-2 receptor antagonist with a K i of 8.5 nM. CT1812 can be used for the research of Alzheimers disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sigma-2 receptor antagonist 1. CAS No. 1802632-22-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111669. | |
| CTB | CTB is a potent p300 histone acetyltransferase activator [1]. CTB can effectively induce apoptosis in MCF-7 cells [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 451491-47-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134964. | |
| CTCE-9908 | CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1030384-98-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1103. | |
| CTEP | CTEP (RO 4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC 50 of 2.2 nM, and shows > 1000-fold selectivity over other mGlu receptors. CTEP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO 4956371; mGluR5 inhibitor. CAS No. 871362-31-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15445. | |
| CTP | CTP is a cardiac targeting peptide. CTP transduces cardiomyocytes in vitro. CTP leads to efficient and specific transduction of heart tissue in mice model. CTP can be used to deliver therapeutic peptides, proteins and nucleic acid specifically to the heart [1]. Uses: Scientific research. Group: Peptides. CAS No. 1052692-86-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P4094. | |
| CTPB | CTPB is a good activator of p300 histone acetyl transferase ( HAT ) enzyme [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 586976-24-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124960. | |
| CTX1 | CTX1 is a p53 activator that overcomes HdmX-mediated p53 repression. CTX1 exhibits potent anti-cancer activity in a mouse acute myeloid leukemia (AML) model system [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 501935-96-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-U00442. | |
| CTX-471 | CTX-471 is a fully human monoclonal antibody of CD137. CTX-471 has bind affinity for recombinant human, cynomolgus macaque CD137 and mouse CD137 with K d values of 50 nM, 61 nM and 748 nM, respectively. CTX-471 can be used for the research of immunomodulation and cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2377152-49-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99178. | |
| CTX-712 | CTX-712 is an orally effective CLK 2 inhibitor, with an IC 50 of 1.4 nM, showing anti-tumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2144751-78-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144875. | |
| CU-32 | CU-32 is a potent cGAS inhibitor with an IC 50 of 0.45 μM. CU-32 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2400954-16-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-132221. | |
| CuATSM | CuATSM is a copper complex that scavenges free radicals, inhibits lipid peroxidation and ferroptosis. CuATSM exhibits antioxidant, anti-inflammatory and neuroprotective activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 68341-09-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139827. | |
| CU-CPT 4a | CU-CPT 4a (TLR3-IN-1) is a potent, highly selective TLR3 signaling inhibitor. CU-CPT 4a represses the expression of downstream signaling pathways mediated by the TLR3/dsRNA complex, including TNF-α and IL-1β [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TLR3-IN-1. CAS No. 1279713-77-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108473. | |
| Cucurbit[7]uril | Cucurbit[7]uril is a cyclic organic molecule consisting of seven glycoluril units linked by methylene bridges. It has a rigid barrel-like structure with two identical inlets at both ends to selectively encapsulate guest molecules of appropriate size, shape, and polarity. Cucurbit[7]uril is known for its high binding affinity for a variety of organic and inorganic guests, including drugs, amino acids, peptides, and metal ions. This property makes them promising candidates for various applications in areas such as drug delivery, catalysis, and sensing. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: CB7; Carrier CB7. CAS No. 259886-50-5. Pack Sizes: 25 mg; 50 mg. Product ID: HY-104086. | |
| Cucurbit[8]uril | Cucurbit[8]uril is a potent, low toxicity and orally active supramolecular inducer of protein heterodimerization. Cucurbit[8]uril induces heterodimerization of methylviologen and naphthalene functionalized proteins. Cucurbit[8]uril can induce energy transfer [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 259886-51-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103689. | |
| Cucurbitacin B | Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 6199-67-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0416. | |
| Cucurbitacin D | Cucurbitacin D is the active ingredient in Trichosanthes kirilowii and can disrupt the interaction between Hsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D is an inflammasome activator. Cucurbitacin D induces cell cycle arrest and cell apoptosis , exhibiting anti-tumor and anti-inflammatory effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 3877-86-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N1986. | |
| Cucurbitacin IIa | Cucurbitacin IIa is a triterpene isolated from Hemsleya amalils Diels, induces apoptosis of cancer cells, reduces expression of survivin , reduces phospho-Histone H3 and increases cleaved PARP in cancer cells [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Hemslecin A. CAS No. 58546-34-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N1988. | |
| Cucurbituril | Cucurbituril is a container molecule resembling a hollow pumpkin, with two identical inlets at each end and a hydrophobic cavity in the middle. Cucurbiturils have unique chemical properties that allow them to selectively encapsulate guest molecules such as drugs or catalysts within their cavities, shielding them from the surrounding environment. Cucurbituril has important potential applications in various fields such as drug delivery, catalysis and materials science. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 80262-44-8. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-W130354. | |
| CUDA | CUDA is a potent inhibitor of soluble epoxide hydrolase (sEH) , with IC 50 s of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively [1]. CUDA selectively increases peroxisome proliferator-activated receptor (PPAR) alpha activity. CUDA may be valuable for the research of cardiovascular disease [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 479413-68-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121538. | |
| CUDC-101 | CUDC-101 is a potent inhibitor of HDAC , EGFR , and HER2 with IC 50 s of 4.4, 2.4, and 15.7 nM, respectively. CUDC-101 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1012054-59-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10223. | |
| Cudetaxestat | Cudetaxestat (BLD-0409) is a potent and orally active autotaxin (ATX) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLD-0409. CAS No. 1782070-21-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145561. | |
| Cue-lure | Cue-lure (Q-lure) is a melon fly attractant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Q-lure. CAS No. 3572-6-3. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-N7099. | |
| CUG | CUG (3-Carboxyumbelliferyl-β-D-galactopyranoside) is a fluorogenic substrate (λ ex =386, λ em =445 nm, ε=32K). Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 3-Carboxyumbelliferyl-β-D-galactopyranoside. CAS No. 64664-99-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1026. | |
| Cu(II) protoporphyrin IX | Cu (II) Protoporphyrin IX is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase). Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation and inflammation, and associated with vascular repair [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 14494-37-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136476B. | |
| Cuminaldehyde | Cuminaldehyde is the main component of Cuminum cyminum and has multiple biological activities, including anti-inflammatory, anti-cancer, anti-diabetic, anti-injury, anti-neuropathy and antibacterial effects. Cuminaldehyde is an inhibitor of aldose reductase ( IC 50 = 0.00085 mg/mL), α-glucosidase ( IC 50 =0.5 mg/mL) and lipoxygenase ( IC 50 =1370 μM). Cuminaldehyde also inhibits the fibrillation of α-synuclein and prevents its aggregation. Cuminaldehyde has potential application value in the research of neurodegenerative diseases, cancer, diabetes and neuropathic pain diseases [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. Alternative Names: p-Isopropylbenzaldehyde. CAS No. 122-03-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-Y0790. | |
| Cuprizone | Cuprizone is a copper chelating agent that forms a deep blue copper ketone complex with copper (II). The copper ketone reaction can be used in colorimetric tests for the presence of trace copper. Cuprizone can be used to induce some schizophrenia-like behavior in mice. Cuprizone acts on copper enzymes, including SOD1, cytochrome oxidase, and DβH, thereby causing oxidative stress and increasing DA levels in certain brain regions such as the medial prefrontal cortex (PFC) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 370-81-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-W115718. | |
| Cuprous iodide | Cuprous iodide (Copper(I) iodide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Copper(I) iodide. CAS No. 7681-65-4. Pack Sizes: 25 g. Product ID: HY-Y0961. | |
| Curcumenol | Curcumenol ((+)-Curcumenol) is a potent CYP3A4 inhibitor with an IC 50 of 12.6 μM, which is one of constituents in the plants of medicinally important genus of Curcuma zedoaria , with neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. Curcumenol ((+)-Curcumenol) suppresses Akt-mediated NF-κB activation and p38 MAPK signaling pathway in LPS-stimulated BV-2 microglial cells [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Curcumenol. CAS No. 19431-84-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N2259. | |
| Curcumin | Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin shows inhibitory effects on NF-κB and MAPKs , and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification. Uses: Scientific research. Group: Natural products. Alternative Names: Diferuloylmethane; Natural Yellow 3; Turmeric yellow. CAS No. 458-37-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0005. | |
| Curcumin-β-D-glucuronide | Curcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 227466-72-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138795. | |
| Curcumin (Standard) | Curcumin (Standard) is the analytical standard of Curcumin. This product is intended for research and analytical applications. Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification. Uses: Scientific research. Group: Natural products. CAS No. 458-37-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0005R. | |
| Curdlan | Curdlan is a polysaccharide found in bacteria, consisting of a glucose homopolymer with β-1,3-glycosidic linkages [1]. Curdlan can be recognized by Dectin-1 (a C-type lectin receptor), inducing immune responses in tissue mast cells and enhancing dendritic cell effects in tumor immunity. Curdlan holds potential for research in cancer and immune-inflammatory diseases [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54724-00-4. Pack Sizes: 500 mg. Product ID: HY-131166. | |
| Curvulin | Curvulin is a phytotoxin [1]. Curvularin inhibits microtubule assembly and inhibits iNOS expression. Uses: Scientific research. Group: Signaling pathways. CAS No. 19054-27-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-119692. | |
| Curzerene | Curzerene is a sesquiterpene is isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity. Curzerene inhibits glutathione S-transferase A1 ( GSTA1 ) mRNA and protein expression. Curzerene induces cell apoptosis [1]. Uses: Scientific research. Group: Natural products. CAS No. 17910-09-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N1963. | |
| Curzerenone | Curzerenone is one of constituents of leaf essential oil extracted from L. pulcherrima. Shows slight inhibitory effective against E. coli [1]. Uses: Scientific research. Group: Natural products. CAS No. 20493-56-5. Pack Sizes: 5 mg. Product ID: HY-N3651. | |
| Cusatuzumab | Cusatuzumab (ARGX-110) is a human αCD70 monoclonal antibody. Cusatuzumab has the activity of enhancied antibody-dependent cellular cytotoxicity (ADCC). Cusatuzumab blocks the CD70/CD27 signaling pathway, reduces leukemia stem cells (LSCs) and triggers gene signatures related to myeloid differentiation and apoptosis. Cusatuzumab can be used to study leukemia [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ARGX-110. CAS No. 1864871-20-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99014. | |
| CVN424 | CVN424 is an orally active and selective GPR6 inverse agonist with a K i of 9.4 nM and an EC 50 of 38 nM. CVN424 is brain-penetrant and has the potential for Parkinson disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2254706-21-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134661A. | |
| CVT-313 | CVT-313 (Cdk2 Inhibitor III) is a potent, selective, reversible, and ATP-competitive inhibitor of CDK2 with IC 50 of 0.5 μM. CVT-313 inhibits CDC5L phosphorylation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cdk2 Inhibitor III. CAS No. 199986-75-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15339. | |
| CWHM-1008 | CWHM-1008 is a potent and orally active antimalarial agent, with EC 50 values of 46 and 21 nM against agent-sensitive Plasmodium falciparum 3D7 and drug-resistant Dd2 strains, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2362539-97-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-111746. | |
| CX516 | CX516 (BDP 12) is an ampakine and acts as an AMPA receptor positive allosteric modulator for the research of Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BDP 12. CAS No. 154235-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10933. | |
| CX546 | CX546 is a first-generation and selective benzamide-type positive AMPAR modulator. CX546 is a prototypical ampakine agent and has antipsychotic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 215923-54-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12505. | |
| CX-6258 hydrochloride hydrate | CX-6258 hydrochloride hydrate is a potent and kinase selective pan-Pim kinases inhibitor, with IC 50 s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1353858-99-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18095A. | |
| CX 717 | CX 717 is a positive allosteric modulator of AMPA receptor. Antidepressant-like effect. CX 717 can be used for the research of adult attention deficit hyperactivity disorder (ADHD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 867276-98-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139897. | |
| CXCR2 antagonist 2 | CXCR2 antagonist 2 is a potent CXCR2 antagonist for cancer immunoresearch with an IC 50 value of 95 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 2647464-91-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139873. | |
| Cy3B NHS ester | Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides. Uses: Scientific research. Group: Fluorescent dye. CAS No. 228272-52-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1849. | |
| Cy3 maleimide chloride | Cy3 maleimide chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing maleimide functional groups. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 maleimide chloride can undergo a "thiol-acrylamide" reaction with molecules containing sulfur-oxygen functional groups to form covalent bonds. Cy3 maleimide chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1838643-41-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1871. | |
| Cy5.5 | Cy5.5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis [1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Sulfo-Cyanine5.5. CAS No. 210892-23-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0924. | |
| Cy5.5-COOH | CY5.5-COOH (Cyanine 5.5 carboxylic acid) is a fluorescent dye, is commonly used in bioimaging. CY5.5-COOH shows narrow absorption spectrum, and high sensitivity and stability [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Cyanine 5.5 carboxylic acid. CAS No. 1449612-07-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-D1040. | |
| Cy5.5 DBCO | Cy5.5 DBCO is a click chemistry reagent containing an cycloalkynes group. Cy5.5 DBCO is a linker of Cyanine5.5 fluorophore. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1857352-95-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-151720. | |
| Cy5-DBCO | Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR) red fluorescent dye with λ abs and λ em of 646nm and 670 nm, respectively. Cy5-DBCO (DBCO-Sulfo-Cy5) is not suitable for staining intracellular components of permeabilezed cell, it may exhibits a high background. Cy5-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: DBCO-Sulfo-Cy5. CAS No. 1564286-24-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D1068. | |
| Cy 5 hydrazide | Cy 5 hydrazide (Cyanine5 hydrazide) is a fluorescent dye for aldehydes and ketones. Cy 5 hydrazide can be used for labeling proteins [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Cyanine5 hydrazide. CAS No. 1427705-31-4. Pack Sizes: 1 mg. Product ID: HY-137100. | |
| Cy7.5 NHS ester | Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2708152-94-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1567. | |
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