MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Dapivirine | Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI). Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TMC120; R147681. CAS No. 244767-67-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14266. |  |
| Dap-NE hydrochloride | Dap-NE hydrochloride is a dipeptide hydrochloride and a cleavable ADC Linker.Dap-NE hydrochloride can be used to connect Antibody and toxin molecules (Cytotoxin) to synthesize Antibody-Drug Conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2019182-02-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-78932A. | |
| Dapoxetine hydrochloride | Dapoxetine (LY-210448) hydrochloride is an orally active and selective serotonin reuptake inhibitor ( SSRI ). Dapoxetine hydrochloride can be used for the research of premature ejaculation (PE) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY-210448 hydrochloride. CAS No. 129938-20-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0304A. | |
| Daprodustat | Daprodustat (GSK1278863) is an orally active hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor being developed for the treatment of anemia associated with chronic kidney disease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK1278863. CAS No. 960539-70-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17608. | |
| Dapsone | Dapsone (4,4-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities [1]. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4,4-Diaminodiphenyl sulfone; DDS. CAS No. 80-08-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0688. | |
| Dapsone hydroxylamine | Dapsone hydroxylamine (DDS-NOH) induces methemoglobinemia. Dapsone hydroxylamine inhibits catalase (CAT) activity and reactive oxygen species generation. Dapsone hydroxylamine also has anti-inflammatory activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DDS-NOH. CAS No. 32695-27-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-137155. | |
| DAPT | DAPT (GSI-IX) is a potent and orally active γ-secretase inhibitor with IC 50 s of 115 nM and 200 nM for total amyloid-β (Aβ) and Aβ 42 , respectively. DAPT inhibits the activation of Notch 1 signaling and induces cell differentiation. DAPT also induces autophagy and apoptosis. DAPT has neuroprotection activity and has the potential for autoimmune and lymphoproliferative diseases, degenerative disease and cancers treatment [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSI-IX. CAS No. 208255-80-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13027. | |
| DAPTA | DAPTA is a synthetic peptide, functions as a viral entry inhibitor by targeting selectively CCR5 , and shows potent anti-HIV activities. Uses: Scientific research. Group: Peptides. Alternative Names: D-Ala-peptide T-amide; Adaptavir. CAS No. 106362-34-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1034. | |
| Daptomycin | Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms. Uses: Scientific research. Group: Peptides. Alternative Names: LY146032. CAS No. 103060-53-3. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0108. | |
| D-arabinose | D-arabinose is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 10323-20-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-N0059. | |
| D-?Arabinose | D-Arabinose, a monosaccharide, shows strong growth inhibition against the Caenorhabditis elegans with an IC 50 of 7.5 mM [1]. Uses: Scientific research. Group: Natural products. CAS No. 28697-53-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-N7082. | |
| D-Arabitol | D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in human. Uses: Scientific research. Group: Natural products. CAS No. 488-82-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-N3686. | |
| Darapladib | Darapladib (SB-480848) is an orally active, selective and reversible Lp-PLA2 inhibitor ( IC 50 =0.25 nM). Darapladib can trigger irreversible actions on glioma cell apoptosis and induce cycle arrest. Darapladib can be used in the study of atherosclerosis and cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-480848. CAS No. 356057-34-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10521. | |
| Daratumumab | Daratumumab (Anti-Human CD38) is the first-in-class human-specific anti-CD38 monoclonal antibody (IgG1). Daratumumab has anti-multiple myeloma (MM) effect. Daratumumab impairs MM cell adhesion, which results in an increased sensitivity of MM to proteasome inhibition [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human CD38, Human Antibody. CAS No. 945721-28-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9915. | |
| Darbufelone mesylate | Darbufelone mesylate (CI-1004 mesylate) is a dual inhibitor of cellular PGF 2α and LTB 4 production. Darbufelone potently inhibits PGHS-2 ( IC 50 = 0.19 μM) but is much less potent with PGHS-1 ( IC 50 = 20 μM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI-1004 mesylate. CAS No. 139340-56-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101438A. | |
| Darexaban | Darexaban (YM150) is a potent, selective and orally active factor Xa (FXa) inhibitor with an IC 50 of 54.6 nM. Darexaban shows high selectivity against other related serine proteases, such as trypsin, thrombin, and kallikrein. Darexaban has anticoagulant and antithrombotic effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YM150. CAS No. 365462-23-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14853. | |
| Darifenacin | Darifenacin (UK-88525) is a selective and orally active M3 muscarinic receptor ( M3R ) antagonist with a pKi of 8.9. Darifenacin binds >20-fold more specifically to M3R than to other muscarinic receptors. Darifenacin can be used in the study of urinary incontinence and other symptoms of overactive bladder. Darifenacin inhibits tumor growth in colorectal cancer cells and has anti-tumor effects [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK-88525. CAS No. 133099-04-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0033. | |
| (±)-Darifenacin | (±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective M3 muscarinic receptor antagonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-UK-88525. CAS No. 133033-93-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-22437. | |
| Darifenacin hydrobromide | Darifenacin (UK-88525) hydrobromide is a selective and orally active M3 muscarinic receptor ( M3R ) antagonist with a pKi of 8.9. Darifenacin hydrobromide binds >20-fold more specifically to M3R than to other muscarinic receptors. Darifenacin hydrobromide can be used in the study of urinary incontinence and other symptoms of overactive bladder. Darifenacin hydrobromide inhibits tumor growth in colorectal cancer cells and has anti-tumor effects [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK-88525 hydrobromide. CAS No. 133099-07-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0012. | |
| Darinaparsin | Darinaparsin (ZIO-101), an organic arsenical, is a mitochondrial-targeted agent. Darinaparsin induces apoptosis in ancer cells, and has anticancer effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZIO-101; S-Dimethylarsino-glutathione. CAS No. 69819-86-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-14943. | |
| Darolutamide | Darolutamide (ODM-201;BAY-1841788) is a potent androgen receptor ( AR ) antagonist with an IC 50 of 26 nM in in vitro assay. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ODM-201; BAY-1841788. CAS No. 1297538-32-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16985. | |
| Darovasertib | Darovasertib (LXS196) is a potent, selective and orally active protein kinase C ( PKC ) inhibitor, with IC 50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively. Darovasertib has the potential for uveal melanoma research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LXS196; IDE196. CAS No. 1874276-76-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101569. | |
| Darunavir | Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC 50 = 0.003 μM; IC 90 = 0.009 μM) with minimal cytotoxicity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TMC114; UIC-94017. CAS No. 206361-99-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17040. | |
| Darunavir Ethanolate | Darunavir ethanolate (TMC114 Ethanolate) is a potent HIV protease inhibitor used to treat and prevent HIV/AIDS. Darunavir has a K i of 1 nM for wild type HIV-1 protease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TMC114 Ethanolate. CAS No. 635728-49-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17041. | |
| Darusentan | Darusentan (Lu-135252) is a selective endothelin receptor A ( ET-A ) receptor antagonist, which binds with a K i of 1.4 nM to the ET-A receptor and a K i of 184 nM to ET-B receptor, respectively with a 100-fold selectivity for ETA rather than ETB receptors [1]. Darusentan competes for radiolabeled endothelin binding in rat aortic vascular smooth muscle cells (RAVSMs) membranes with single-site kinetics, exhibiting a K i of 13 nM [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu-135252. CAS No. 171714-84-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15404. | |
| Darutoside | Darutoside is a diterpenoid isolated from Siegesbeckia [1]. Uses: Scientific research. Group: Natural products. CAS No. 59219-65-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N6028. | |
| Dasabuvir | Dasabuvir (ABT-333) is a nonnucleoside hepatitis C virus (HCV) polymerase inhibitor. Dasabuvir inhibits RNA-dependent RNA polymerase encoded by the HCV NS5B gene. Dasabuvir inhibits genotype 1a (strain H77) and 1b (strain Con1) replicons, with EC 50 values of 7.7 and 1.8 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-333. CAS No. 1132935-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13998. | |
| Dasatinib | Dasatinib (BMS-354825) is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The K i s are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib inhibits Bcr-Abl and Src with IC 50 s of <1.0 nM and 0.5 nM, respectively [1]. Dasatinib also induces apoptosis and autophagy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-354825. CAS No. 302962-49-8. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10181. | |
| Dasatinib analog-1 | Dasatinib analog-1 (compound 5826) inhibits CYP3A4 viability with a K i value of 5.4 μM. Dasatinib analog-1 blocks the formation of glutathione adducts [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1174416-41-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156883. | |
| Dasatinib-d8 | Dasatinib-d 8 is a deuterium labeled Dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: BMS-354825-d8. CAS No. 1132093-70-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-10181S. | |
| Dasatinib hydrochloride | Dasatinib (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The K i s are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride inhibits Bcr-Abl and Src with IC 50 s of <1.0 nM and 0.5 nM, respectively [1]. Dasatinib hydrochloride also induces apoptosis and autophagy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-354825 hydrochloride. CAS No. 854001-07-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-10181A. | |
| Dasatinib monohydrate | Dasatinib (BMS-354825) monohydrate is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The K i s are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib monohydrate inhibits Bcr-Abl and Src with IC 50 s of <1.0 nM and 0.5 nM, respectively [1]. Dasatinib monohydrate also induces apoptosis and autophagy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-354825 monohydrate. CAS No. 863127-77-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-10181B. | |
| Dasatinib N-oxide | Dasatinib N-oxide is a minor metabolite of Dasatinib. Dasatinib is a potent and orally active dual Src/Bcr-Abl inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 910297-52-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-133794. | |
| Dasotraline hydrochloride | Dasotraline hydrochloride (SEP-225289 hydrochloride) is a triple reuptake inhibitor that blocks dopamine , norepinephrine , and serotonin transporters with IC 50 values of 4, 6, and 11 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SEP-225289 hydrochloride. CAS No. 675126-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12850A. | |
| D-Asparagine | D-Asparagine (H-D-Asn-OH) is a competitive inhibitor of L-Asparagine hydrolysis with a K i value of 0.24 mM. D-Asparagine is a source of nitrogen for yeast strains. D-Asparagine is a good substrate for the external yeast asparaginase but is a poor substrate for the internal enzyme [1]. Uses: Scientific research. Group: Natural products. Alternative Names: H-D-Asn-OH. CAS No. 2058-58-4. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-W010378. | |
| Datelliptium chloride | Datelliptium chloride is a DNA-intercalating agent derived from ellipticine, with anti-tumor activities. Uses: Scientific research. Group: Signaling pathways. CAS No. 105118-14-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00337. | |
| Datopotamab | Datopotamab (CDP7657) is a humanized anti trophoblast cell surface antigen 2 ( TROP2 ) antibody. Datopotamab can generate antibody drug conjugates (ADC) (HY-141598) with DNA topoisomerase I inhibitor Deruxtecan (HY-13631E). Datopotamab can be used in the study of triple negative breast cancer and non-small cell lung cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2267989-53-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99843. | |
| Datopotamab deruxtecan | Datopotamab deruxtecan (DS-1062; Dato-DXd) is a trophoblast cell surface antigen 2 (TROP2)-directed antibody-drug conjugate (ADC). Datopotamab deruxtecan has a potent antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DS-1062; Dato-DXd. CAS No. 2238831-60-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141598. | |
| Daucosterol | Daucosterol is an orally active natural sterol compound, which has anti-inflammatory, anticancer and immunomodulatory activities. Daucosterol inhibits cancer cell proliferation by inducing autophagy through ROS-dependent manner. Daucosterol also inhibits colon cancer growth by inducing apoptosis, inhibiting cell migration and invasion and targeting caspase signalling pathway [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Eleutheroside A; β-Sitosterol β-D-glucoside. CAS No. 474-58-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N0410. | |
| DAUDA | DAUDA (11-(dansylamino) undecanoic acid) is an environment-sensitive fluorescent fatty acid analogue. DAUDA alters its intensities and fluorescent emission spectra on entry into binding proteins. DAUDA is used to determine the relative affinity of natural fatty acids for polymorphs of the Schistosoma mansoni Sm14 fatty acid-binding protein[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 73025-02-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-120959. | |
| Daunomycinone | Daunomycinone (NSC-109351) is a metabolite of daunomycin. Daunomycin is an antibiotic with antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC-109351. CAS No. 21794-55-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114658. | |
| Daunorubicin hydrochloride | Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin hydrochloride inhibits DNA and RNA synthesis. Daunorubicin hydrochloride is a cytotoxin that inhibits cancer cell viability and induces apoptosis and necrosis. Daunorubicin hydrochloride is also an anthracycline antibiotic. Daunorubicin hydrochloride can be used in the research of infection and variety of cancers, including leukemia, non-Hodgkin lymphomas, Ewing's sarcoma, Wilms' tumor [1] [2] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Daunomycin hydrochloride; RP 13057 hydrochloride; Rubidomycin hydrochloride. CAS No. 23541-50-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13062. | |
| Dauricine | Dauricine, a bisbenzylisoquinoline alkaloid in Menispermum dauricum , possesses anti-inflammatory activity. Dauricine inhibits cell proliferation and invasion, and induces apoptosis by suppressing NF-κB activation in a dose- and time-dependent manner in colon cancer [1]. Uses: Scientific research. Group: Natural products. CAS No. 524-17-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0220. | |
| DavePhos | DavePhos is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 213697-53-1. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-W002925. | |
| Davunetide | Davunetide is an eight amino acid snippet derived from activity-dependent neuroprotective protein (ADNP), a neurotrophic factor that exists in the mammalian CNS. Davunetide possesses neuroprotective, neurotrophic and cognitive protective roperties. Davunetide, a microtubule-stabilizing peptide, interacts with and stabilises neuron-specific βIII-tubulin in vitro. Davunetide penetrates the blood-brain barrier and is non-toxic. Davunetide inhibits Aβ aggregation and Aβ-induced neurotoxicity [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 211439-12-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-105066. | |
| Davutamig | Davutamig (REGN-5093) is a humanIgG4-kappa, anti-MET bispecific antibody targeting two different nonoverlapping epitopes on MET. Davutamig is an antineoplastic agent [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN-5093. CAS No. 2648058-48-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990073. | |
| Daxdilimab | Daxdilimab is an anti-ILT7 monoclonal antibody, ILT7 is a cell surface molecule specific to the pDC type of dendritic cells. Daxdilimab can be used in acute lung injury (ALI) in patients with COVID-19 infection research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI7734; VIB7734. CAS No. 2245966-28-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99226. | |
| Dazodalibep | Dazodalibep (MEDI 4920; VIB 4920) is a fusion protein targeting CD40LG/TNFSF5 fused to human serum albumin ALB/HSA [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI 4920; VIB 4920. CAS No. 2245953-10-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99845. | |
| Dazoxiben hydrochloride | Dazoxiben hydrochloride is a potent and orally active thromboxane (TX) synthase inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK 37248. CAS No. 74226-22-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106067A. | |
| Dazucorilant | Dazucorilant (CORT113176) is a selective and high affinity non-steroidal glucocorticoid receptor ( GR ) modulator with a K i value ?1 nM in vitro. Dazucorilant can be used for the research of neurological disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CORT113176. CAS No. 1496508-34-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-132811. | |
| Dazukibart | Dazukibart is a mouse-derived, humanized IgG1κ antibody targeting interferon beta 1 ( IFNB1 ) [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2639474-65-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990036. | |
| DB18 | DB18 is a potent and selective inhibitor of CDC2-like kinases (CLKs) , with IC 50 values in the range of 10-30 nM for CLK1, CLK2 and CLK4. DB18 has anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2587177-94-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-131978. | |
| DB2115 tertahydrochloride | DB2115 (tertahydrochloride) is a potent inhibitor of myeloid master regulator PU.1. DB2115 (tertahydrochloride) has the potential for researching cancers, including hematologic cancers such as leukemia, as well as other conditions associated with PU. 1 dysfunction (extracted from patent WO2017223260A1, compound DB2115) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1366126-19-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124676A. | |
| DB28 | DB28 is a novel MR1 ligand. DB28 decreases cell surface expression of MR1 and competitively inhibits activation of MAIT cells by agonist ligands [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 16296-42-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W168754. | |
| DB775 | DB775 is a metabolite of DB289 (HY-14932) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 475976-08-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-164025. | |
| DBCO-acid | DBCO-acid is a click chemistry reagent used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690). DBCO-acid contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1353016-70-2. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-42972. | |
| DBCO-amine | DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1255942-06-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W000423. | |
| DBCO-Biotin | DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [1]. DBCO-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1418217-95-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123916. | |
| DBCO-Cy3 | DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dye with excitation maximum 555 nm and emission maximum of 580nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations. DBCO-Cy3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: DBCO-Sulfo-Cy3. CAS No. 1782950-79-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D1069. | |
| DBCO-Maleimide | DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1395786-30-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-116270. | |
| DBCO-NHS ester | DBCO-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1353016-71-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-42973. | |
| DBCO-PEG2-NHS ester | DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2585653-12-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151827. | |
| DBCO-PEG3-NHS ester | DBCO-PEG3-NHS ester (cpmpd 45) is a ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2163772-16-3. Pack Sizes: 25 mg; 50 mg. Product ID: HY-156507. | |
| DBCO-PEG4-Biotin | DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction [1]. DBCO-PEG4-Biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1255942-07-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-130809. | |
| DBCO-PEG4-DBCO | DBCO-PEG4-DBCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2182601-68-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-130346. | |
| DBCO-PEG4-Desthiobiotin | DBCO-PEG4-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. DBCO-PEG4-Desthiobiotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2032788-37-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-140301. | |
| DBCO-PEG4-Maleimide | DBCO-PEG4-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1480516-75-3. Pack Sizes: 25 mg. Product ID: HY-120770. | |
| DBCO-PEG5-NHS ester | DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1] [2]. DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2144395-59-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126885. | |
| DBCO-Sulfo-Link-biotin | DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-Sulfo-Link-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1363444-70-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-130810. | |
| DBCO-Sulfo-Link-biotin TEA | DBCO-Sulfo-Link-biotin TEA is a click chemistry intermediate containing a DBCO group, which can undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group. Uses: Scientific research. Group: Signaling pathways. CAS No. 1485489-28-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W123019. | |
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