MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Denintuzumab | Denintuzumab (hBU 12) is a recombinant humanized anti-CD19 monoclonal antibody. Denintuzumab can be used as the antibody moiety ( ADC antibody ) of antibody-drug conjugates to synthesize ADC, Denintuzumab Mafodotin (SGN-CD19A). Denintuzumab Mafodotin can be used in the research of acute lymphoblastic leukemia [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: hBU 12. CAS No. 1630074-14-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99285. |  |
| Denosumab | Denosumab is a human monoclonal antibody that targets the protein RANKL. Denosumab binds to the receptor activator of nuclear factor kappa-B ligand (RANKL) and prevents its binding to the RANK receptor ( K D of 0.003 nM for human RANKL). Denosumab promotes proliferation and spermatogenesis. Denosumab prevents bone resorption through inhibition of the NF-κB pathway. Denosumab can be used in bone-related studies [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG-162. CAS No. 615258-40-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9958. | |
| De-N-sulfated heparin sodium salt | De-N-sulfated heparin (Heparin I-H) sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Heparamine sodium salt. CAS No. 61932-66-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W145658. | |
| Dentonin | Dentonin (AC-100) is a synthetic fragment derived from MEPE. Dentonin enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin has no significant effect to mature osteoblasts. Dentonin can be used for the research of phosphate homeostasis and bone metabolism [1]. Uses: Scientific research. Group: Peptides. Alternative Names: AC-100. CAS No. 400090-20-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2633. | |
| (-)-Denudatin B | (-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B relaxed vascular smooth muscle by inhibiting the Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels [1]. And (-)-Denudatin B has nonspecific antiplatelet action. Uses: Scientific research. Group: Natural products. Alternative Names: Denudatin B. CAS No. 87402-88-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N3729. | |
| Deoxyandrographolide | Deoxyandrographolide suppresses LPS induced increase in mRNA levels of iNOS as well as production of proinflammatory mediators TNF-α and IL-6. Deoxyandrographolide potentiates NGF-induced neurite outgrowth [1]. Uses: Scientific research. Group: Natural products. CAS No. 79233-15-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0857. | |
| Deoxyarbutin | Deoxyarbutin is an orally active tyrosinase inhibitor that can promote apoptosis of melanoma cells, enhance the vitality of mouse acinar cells, and has skin whitening and anti-tumor activity [1][2][3]. Uses: Scientific research. Group: Natural products. CAS No. 53936-56-4. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-B1461. | |
| Deoxy-bigchap | Deoxy-bigchap is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 86303-23-3. Pack Sizes: 10 mg; 25 mg. Product ID: HY-W250173. | |
| Deoxycholic acid | Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptor TGR5 [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cholanoic Acid; Desoxycholic acid. CAS No. 83-44-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0593. | |
| Deoxycholic acid sodium salt | Deoxycholic acid sodium salt (sodium deoxycholate), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptor TGR5 [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium deoxycholate. CAS No. 302-95-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-N0593A. | |
| Deoxycorticosterone | Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. Deoxycorticosterone is an agonist for O. mykiss mineralocorticoid receptor ( rtMR ) transcription with EC 50 of 0.16 nM [3]. Deoxycorticosterone could acts as an immune stimulator in fish [4]. Uses: Scientific research. Group: Natural products. CAS No. 64-85-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-113414. | |
| Deoxycorticosterone acetate | Deoxycorticosterone acetate (DOCA) is an adrenocortin, acts as a precursor to aldosterone. Deoxycorticosterone acetate is a mineralocorticoid receptor agonist. Deoxycorticosterone acetate can cause severe renal injury, including inflammation, fibrosis, glomerular damage, and proteinuria [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 11-Deoxycorticosterone acetate; DOC acetate; Cortexone acetate. CAS No. 56-47-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1472. | |
| Deoxycytidine triphosphate | Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: dCTP; 2-Deoxycytidine-5-triphosphate. CAS No. 2056-98-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-101400. | |
| Deoxycytidine triphosphate disodium | Deoxycytidine triphosphate (disodium) (dCTP (disodium); 2-Deoxycytidine-5-triphosphate (disodium)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: dCTP disodium; 2-Deoxycytidine-5-triphosphate disodium. CAS No. 102783-51-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W010771. | |
| Deoxyfuconojirimycin hydrochloride | Deoxyfuconojirimycin hydrochloride is a specific competitive inhibitor of human liver α-L-fucosidase. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 210174-73-5. Pack Sizes: 5 mg. Product ID: HY-126306. | |
| Deoxynivalenol | Deoxynivalenol, an orally active mycotoxin of the trichothecenes family, crosses the intestinal mucosa by a paracellular pathway through the tight junctions. The Deoxynivalenol transport is not affected by P-glycoprotein (PgP) or multidrug resistance-associated proteins (MRPs) inhibitors [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Vomitoxin. CAS No. 51481-10-8. Pack Sizes: 1 mg. Product ID: HY-N6684. | |
| Deoxynivalenol-13C15 | Deoxynivalenol- 13 C 15 is the 13 C labeled Deoxynivalenol [1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 911392-36-4. Pack Sizes: 25 μg (80.33 μM * 1 mL in Acetonitrile). Product ID: HY-152072S. | |
| Deoxypodophyllotoxin | Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from Anthriscus sylvestris. Deoxypodophyllotoxin, targets the microtubule , has a major impact in oncology not only as anti-mitotics but also as potent inhibitors of angiogenesis [1]. Deoxypodophyllotoxin induces cell autophagy and apoptosis [2]. Deoxypodophyllotoxin evokes increase of intracellular Ca 2+ concentrations in DRG neurons [3]. Uses: Scientific research. Group: Natural products. CAS No. 19186-35-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2500. | |
| Deoxypyridinoline | Deoxypyridinoline is an endogenous metabolite present in Urine that can be used for the research of Heart Failure [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 83462-55-9. Pack Sizes: 1 mg. Product ID: HY-113495. | |
| Deoxyribonuclease II | Deoxyribonuclease II (DNase II) is an endonuclease that hydrolyzes the phosphodiester bonds of deoxyribonucleotides in native and denatured DNA, producing 3' phosphate and 5'-hydroxyl termini. Deoxyribonuclease II works best at acidic pH and is commonly used in biochemical research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DNase II. CAS No. 9025-64-3. Pack Sizes: 40 KU. Product ID: HY-P2863. | |
| Deoxythymidine-5'-triphosphate (trisodium) solution (100mM) | Deoxythymidine-5'-triphosphate (dTTP) trisodium solution (100mM) is one of the four nucleoside triphosphates used in the synthesis of DNA [1]. Uses: Scientific research. Group: Natural products. Alternative Names: dTTP (trisodium) solution (100mM). CAS No. 27821-54-1. Pack Sizes: 5.48 mg (100 mM * 100 μL in Water); 10.96 mg (100 mM * 200 μL in Water); 27.4 mg (100 mM * 500 μL in Water); 54.81 mg (100 mM * 1000 μL in Water). Product ID: HY-W013715A. | |
| Deoxyvasicinone | Deoxyvasicinone is an alkaloid compound isolated from plants [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 9-Oxodeoxypeganine; Pegenone. CAS No. 530-53-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N3735. | |
| Depatuxizumab | Depatuxizumab is a brain-penetrant and humanized tumor-specific anti EGFR monoclonal antibody. Depatuxizumab inhibits the growth of xenograft models of mutant EGFRvIII and wild-type EGFR. Depatuxizumab can be used for research on cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABT-806. CAS No. 1471999-69-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99849. | |
| Depatuxizumab mafodotin | Depatuxizumab mafodotin is an antibody-drug conjugate ( ADC ) that specifically targets the epidermal growth factor receptor ( EGFR ). Depatuxizumab mafodotin can be used for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-414. CAS No. 1585973-65-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132259. | |
| Depemokimab | Depemokimab (GSK-3511294) is a long-acting anti- IL-15 monoclonal antibody. Depemokimab can be used for research of asthma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GSK-3511294. CAS No. 2243274-14-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99850. | |
| Dephospho-CoA | Dephospho-CoA is a key intermediate in the biosynthesis of coenzyme A (CoA) , which is catalyzed by GTP-dependent dephospho-CoA kinase (DPCK) to generate CoA. Dephospho-CoA completes the final synthesis step of CoA through phosphorylation reaction and participates in energy metabolism and cell signaling. Dephospho-CoA can be used in research including cancer (such as regulating cell proliferation) and metabolic diseases (such as mitochondrial dysfunction) [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 3633-59-8. Pack Sizes: 5 mg. Product ID: HY-137899. | |
| Deprodone propionate | Deprodone propionate (RD20000) is a corticosteroid which is obtained by esterifying with propionic acid the 17-position of the prednisolone skeleton and deoxidating its 21-position. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RD20000. CAS No. 20424-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00190. | |
| Dequalinium Chloride | Dequalinium chloride is an Apamin (HY-P0256)-sensitive potassium channel selective blocker. Dequalinium chloride is a cationic, lipophilic mitochondrial poison. Dequalinium chloride is also an antagonist pf α7 nAChR , and an anti-microbial antiseptic agent with a broad bactericidal and fungicidal activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 522-51-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0567. | |
| Deracoxib | Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC 046; SC 46; SC 59046. CAS No. 169590-41-4. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17509. | |
| Deramciclane | Deramciclane has a high affinity for 5-HT 2A and 5-HT 2C receptors; it acts as an antagonist at both receptor subtypes and has inverse agonist properties at the 5-HT 2C receptors without direct stimulatory agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EGIS-3886. CAS No. 120444-71-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101630. | |
| Derazantinib | Derazantinib (ARQ-087) is an ATP competitive and orally active FGFR inhibitor ( IC 50 s: 1.8 nM for FGFR2, 4.5 nM for FGFR1 and 3 nM). Derazantinib inhibits FGFR phosphorylation. Derazantinib inhibits tumor growth in multiple xenograft models [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARQ-087. CAS No. 1234356-69-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19981. | |
| Derazantinib Racemate | Derazantinib Racemate (ARQ-087 Racemate) is the racemate of Derazantinib. Derazantinib is an orally bioavailable, ATP competitive tyrosine kinase inhibitor; exhibits potent activity against FGFR1-3 chondrocytes with IC 50 s of 4.5, 1.8, and 4.5 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARQ-087 Racemate. CAS No. 2309668-44-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 2 mg. Product ID: HY-19981A. | |
| Dermaseptin | Dermaseptin, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration [1]. Uses: Scientific research. Group: Peptides. CAS No. 136212-91-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0263. | |
| Dermaseptin TFA | Dermaseptin TFA, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration [1]. Uses: Scientific research. Group: Peptides. CAS No. 646451-06-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0263A. | |
| Dermatan sulphate sodium | Dermatan sulphate sodium is an oral active glycosaminoglycan and thrombin inactivator with antithrombotic activity. It selectively catalyzes the heparin cofactor II-mediated inactivation of thrombin without interacting with antithrombin III. Dermatan sulphate sodium promotes stem cell differentiation, exhibits high bioavailability, and alleviates pulmonary fibrosis injury induced by Bleomycin (HY-108345). Dermatan sulphate sodium can be used in research related to cardiovascular diseases, inflammation, and stem cell differentiation [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 54328-33-5. Pack Sizes: 5 mg. Product ID: HY-N8278. | |
| Dermorphin | Dermorphin is a natural heptapeptide μ-opioid receptor ( MOR ) agonist found in amphibian skin. Inhibition of neuropathic pain [1]. Uses: Scientific research. Group: Peptides. CAS No. 77614-16-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P0244. | |
| Dersimelagon | Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor ( MC1R ) agonist with EC 50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon shows good affinity for hMC1R and hMC4R with K i values of 2.26, 32.9 nM, respectively. Dersimelagon can be used for the research of skin pigmentation [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MT-7117. CAS No. 1835256-48-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-109114. | |
| Deruxtecan | Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MC-GGFG-DXD. CAS No. 1599440-13-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13631E. | |
| D-erythro-MAPP | D-erythro-MAPP (D-e-MAPP) is a ceramidase inhibitor, with an IC 50 of 1-5 μM in vitro [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-e-MAPP. CAS No. 143492-38-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-137422. | |
| D-Erythrose 4-phosphate sodium | D-Erythrose 4-phosphate sodium is a phosphate sodium of the simple sugar Erythrose. Erythritol is actually converted into D-Erythrose 4-phosphate that involves three isomerases [1]. Uses: Scientific research. Group: Natural products. CAS No. 103302-15-4. Pack Sizes: 1 mg. Product ID: HY-N7386A. | |
| D-erythro-Sphingosine | D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC 50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Erythrosphingosine; erythro-C18-Sphingosine; trans-4-Sphingenine. CAS No. 123-78-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101047. | |
| D-erythro-Sphingosine-d7 | D-erythro-Sphingosine-d 7 is the deuterium labeled D-erythro-Sphingosine. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Erythrosphingosine-d7; erythro-C18-Sphingosine-d7; trans-4-Sphingenine-d7. CAS No. 1246304-34-6. Pack Sizes: 500 μg. Product ID: HY-101047S. | |
| D-erythro-Sphingosine hydrochloride | D-erythro-Sphingosine (Erythrosphingosine) hydrochloride is a specific TRPM3 activator. D-erythro-Sphingosine also induces retinoblastoma protein dephosphorylation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Erythrosphingosine hydrochloride; erythro-C18-Sphingosine hydrochloride; trans-4-Sphingenine hydrochloride. CAS No. 2673-72-5. Pack Sizes: 25 mg; 50 mg. Product ID: HY-W089922. | |
| Desacetylcefotaxime | Desacetylcefotaxime, the in vivo metabolite of Cefotaxime (CTX), possesses significant in vitro antimicrobial activity similar to the parent compound against a variety of aerobic and anaerobic bacteria [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66340-28-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-126129. | |
| Desacetylcephapirin sodium | Desacetylcephapirin sodium (Deacetylcephapirin sodium) is an active metabolite of Cephapirin (HY-A0153A). Desacetylcephapirin sodium has antimicrobial against S. aureus and coagulase-negative staphylococci mastitis pathogen [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Deacetylcephapirin sodium. CAS No. 104557-24-6. Pack Sizes: 2.5 mg. Product ID: HY-131989. | |
| [Des-Arg9]-Bradykinin acetate | [Des-Arg9]-Bradykinin acetate is a Bradykinin B 1 receptor agonist that displays selectivity for B 1 over B 2 receptors. Uses: Scientific research. Group: Peptides. CAS No. 23827-91-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0298A. | |
| Desbutyl Lumefantrine | Desbutyl Lumefantrine is a metabolite of lumefantrine with antimalarial activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Desbutyl-benflumetol. CAS No. 355841-11-1. Pack Sizes: 1 mg. Product ID: HY-12781. | |
| Deschloroetizolam | Deschloroetizolam is a designer Benzodiazepine. Deschloroetizolam is a psychoactive substance, with physical and cognitive effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 40054-73-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137994. | |
| Desethylamiodarone hydrochloride | Desethylamiodarone hydrochloride (N-desethylamiodarone hydrochloride) is a major active metabolite of Amiodarone. Desethylamiodarone hydrochloride is formed by CYP3A isoenzymes. Amiodarone is an antiarrhythmic agent for inhibition of ATP-sensitive potassium channel with an IC 50 of 19.1 μM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-desethylamiodarone hydrochloride; LB 33020 hydrochloride. CAS No. 96027-74-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-130353. | |
| Desfesoterodine | Desfesoterodine (PNU-200577) is a potent and selective muscarinic receptor (mAChR) antagonist with a K B and a pA 2 of 0.84 nM and 9.14, respectively [1]. Desfesoterodine is a major pharmacologically active metabolite of Tolterodine (PNU-200583; HY-A0024) and Fesoterodine (HY-70053) [2] [3]. Desfesoterodine improves cerebral infarction induced detrusor overactivity in rats [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNU-200577; 5-Hydroxymethyl Tolterodine. CAS No. 207679-81-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-76569. | |
| Desformylflustrabromine hydrochloride | Desformylflustrabromine hydrochloride is a selective agonist of α 4 β 2 neuronal nicotinic acetylcholine receptor ( nAChR ) with a pEC 50 of 6.48. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Deformylflustrabromine hydrochloride; dFBr hydrochloride. CAS No. 951322-11-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107675. | |
| Desfuroylceftiofur | Desfuroylceftiofur is an active metabolite of Ceftiofur which is a broad-spectrum cephalosporin antibiotic. Desfuroylceftiofur is active against gram-positive and gram-negative bacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120882-22-6. Pack Sizes: 1 mg. Product ID: HY-126818. | |
| Desidustat | Desidustat is an orally active HIF hydroxylase inhibitor. Desidustat can be used for the research of various disorders including anemia of different types and conditions associated with ischemia/hypoxia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZYAN1. CAS No. 1616690-16-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103227. | |
| Desipramine-d4 | Desipramine-d 4 is the deuterium labeled Desipramine[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 61361-34-0. Pack Sizes: 500 μg; 1 mg. Product ID: HY-B1272AS. | |
| Desipramine hydrochloride | Desipramine hydrochloride is an inhibitor of norepinephrine transporter ( NET ), 5-HT transporter ( SERT ) and dopamine transporter ( DAT ) with K i s of 4, 61 and 78,720 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 58-28-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1272. | |
| Desisopropylatrazine-d5 | Desisopropylatrazine-d 5 is the deuterium labeled Desisopropylatrazine[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1189961-78-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-146604S. | |
| Desloratadine | Desloratadine (Sch34117) is an orally active and selective H1 receptor antagonist ( K i =0.9 nM) with anti-inflammatory and anti-allergic activities. Desloratadine inhibits the release of histamine and LTC4 from human basophils and targets the regulatory signals of IL-4 and IL-13 production in basophils. Desloratadine significantly alleviates SAR symptoms in patients with concurrent asthma and can be used in the study of seasonal allergic rhinitis and chronic idiopathic urticaria [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Sch34117. CAS No. 100643-71-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-B0539. | |
| Desmethyl Erlotinib | Desmethyl Erlotinib (OSI-420 free base) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor [1]. Desmethyl Erlotinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OSI-420 free base; CP-373420. CAS No. 183321-86-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13256A. | |
| Desmethyl Erlotinib hydrochloride | Desmethyl Erlotinib hydrochloride (OSI-420) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor [1]. Desmethyl Erlotinib (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OSI-420; CP-373420 hydrochloride. CAS No. 183320-51-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13256. | |
| Desmethylflunitrazepam | Desmethylflunitrazepam (Norflunitrazepam) is a compound from the benzodiazepine family and is an active metabolite of Flunitrazepam [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Norflunitrazepam; Ro 05-4435. CAS No. 2558-30-7. Pack Sizes: 1 mg. Product ID: HY-114876. | |
| Desmosterol | Desmosterol is a cholesterol-like molecule. In the Bloch pathway of cholesterol biosynthesis, Desmosterol is a direct precursor of cholesterol. As an endogenous metabolite, Desmosterol is used to study cholesterol metabolism [1]. Desmosterol is an LXR activator and SREBP inhibitor, which can suppress macrophage inflammasome activation and prevent vascular inflammation and atherosclerosis. A reduction in Desmosterol promotes the production of mitochondrial reactive oxygen species ( ROS ) in macrophages and pyrin domain-dependent inflammasome activation of NLRP3. Desmosterol holds potential for research in inflammation, metabolism, and cardiovascular diseases [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 313-04-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113224. | |
| Desmosterol-d6 | Desmosterol-d 6 is the deuterium labeled Desmosterol. Desmosterol is a molecule similar to cholesterol. Desmosterol is the immediate precursor of cholesterol in the Bloch pathway of cholesterol biosynthesis. Desmosterol, as an endogenous metabolite, used to study cholesterol metabolism[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1246298-67-8. Pack Sizes: 500 μg; 1 mg. Product ID: HY-113224S. | |
| Desogestrel | Desogestrel (Org-2969) is a third-generation progesterone analogue contained in many oral contraceptive preparations. Desogestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Org-2969. CAS No. 54024-22-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12516. | |
| Desonide | Desonide is a non-fluorinated corticosteroid anti-inflammatory agent that acts on glucocorticoid receptors. Uses: Scientific research. Group: Signaling pathways. CAS No. 638-94-8. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0248. | |
| Desoximetasone | Desoximetasone (Topicort) is a corticosteroid that can be used to relieve various skin conditions such as rashes. Uses: Scientific research. Group: Signaling pathways. CAS No. 382-67-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17570. | |
| Desoxycorticosterone pivalate | Desoxycorticosterone pivalate (DOCP) is a mineralocorticoid hormone and an analog of Desoxycorticosterone. Desoxycorticosterone pivalate is used for the management of canine hypoadrenocorticism [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 808-48-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107917. | |
| Destruxin B | Destruxin B, isolated from entomopathogenic fungus Metarhizium anisopliae , is one of the cyclodepsipeptides with insecticidal and anticancer activities. Destruxin B induces apoptosis via a Bcl-2 Family -dependent mitochondrial pathway in human nonsmall cell lung cancer cells [1]. Destruxin B significantly activates caspase-3 and reduces tumor cell proliferation through caspase-mediated apoptosis , not only in vitro but also in vivo [2]. Uses: Scientific research. Group: Natural products. CAS No. 2503-26-6. Pack Sizes: 1 mg. Product ID: HY-N6690. | |
| Desvenlafaxine | Desvenlafaxine, the succinate salt form of the isolated major active metabolite of Venlafaxine (HY-B0196), is an orally active and BBB penetrated 5-HT and norepinephrine reuptake inhibitor, with IC 50 values of 47.3 nM and 531.3 nM for hSERT and hNET, respectively. Desvenlafaxine shows weak binding affinity (62% inhibition at 100 μM) at the human dopamine (DA) transporter [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: O-Desmethylvenlafaxine. CAS No. 93413-62-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0602. | |
| Desvenlafaxine succinate hydrate | Desvenlafaxine succinate hydrate, the succinate salt form of the isolated major active metabolite of Venlafaxine (HY-B0196), is an orally active and BBB penetrated 5-HT and norepinephrine reuptake inhibitor, with IC 50 values of 47.3 nM and 531.3 nM for hSERT and hNET, respectively. Desvenlafaxine succinate hydrate shows weak binding affinity (62% inhibition at 100 μM) at the human dopamine (DA) transporter [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: O-Desmethylvenlafaxine succinate hydrate; Desvenlafaxine succinate monohydrate. CAS No. 386750-22-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0602A. | |
| Deterenol hydrochloride | Deterenol hydrochloride (AL842) is a selective beta-agonist. Deterenol hydrochloride causes vasodepressor, anxiety, increasing heart rate, hypotension palpitation and respiratory distress [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AL842. CAS No. 23239-36-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W702027. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.