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Cirtuvivint
Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor. Cirtuvivint can be used for solid tumors research[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SM08502. CAS No. 2143917-62-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137435.
cis-10-Heptadecenoic acid
cis-10-Heptadecenoic acid is a cis-fatty acid. cis-10-Heptadecenoic acid synthesizes polyhydroxy-chain alkanoates under the action of 2, 4-dienyl-CoA reductase and Delta3, Delta2-enyl-CoA isomerase [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 29743-97-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-116037.
cis-2-Butene-1,4-diol
cis-2-Butene-1,4-diol, an industrial product, can be used for the synthesis of antiviral product oxetanocin A. cis-2-Butene-1,4-diol is a probe for studying isomerization versus hydrogenation and hydrogenolysis reactions [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6117-80-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W027631.
cis-3-Hexen-1-ol
cis-3-Hexen-1-ol ((Z)-3-Hexen-1-ol) is a green grassy smelling compound found in many fresh fruits and vegetables with bitter taste enhancement. cis-3-Hexen-1-ol is widely used as an added flavor in processed food to provide a fresh green quality. cis-3-Hexen-1-ol is an attractant to various insects [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (Z)-3-Hexen-1-ol. CAS No. 928-96-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W010607.
cis-3-Hexenyl Hexanoate
cis-3-Hexenyl Hexanoate is an active compound. cis-3-Hexenyl Hexanoate can be isolated from Feijoa sellowiana [1]. Uses: Scientific research. Group: Natural products. Alternative Names: n-Caproic acid cis-3-Hexen-1-yl ester. CAS No. 31501-11-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W014933.
cis-4-Hydroxy-L-proline
cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 618-27-9. Pack Sizes: 50 mg; 100 mg. Product ID: HY-40136.
cis-5-Octen-1-ol
cis-5-Octen-1-ol is an organic compound belonging to alcohols. It has a strong earthy smell and is commonly found in a variety of foods such as fruits, vegetables and spices. cis-5-Octen-1-ol has various applications in the flavor and fragrance industry, especially as a flavoring and aroma enhancer in products such as perfume, cologne and baked goods. In addition, it has potential utility in inhibiting inflammation-related diseases and cancer. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 64275-73-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W101301.
cis-?9,?10-?Epoxystearic acid
cis-9,10-Epoxystearic acid (cis-9,10-Epoxyoctadecanoic acid) is an endogenous constituent in human blood and urine. cis-9,10-Epoxystearic acid (cis-9,10-Epoxyoctadecanoic acid) can be produced from oleic acid by enzymic and non-enzymic epoxidation [1]. Uses: Scientific research. Group: Natural products. Alternative Names: cis-9,10-Epoxyoctadecanoic acid. CAS No. 24560-98-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-129554.
(+)-cis-Abienol
(+)-cis-Abienol (Compound Z-abienol), a diterpenoid, can be isolated from leaves of tobacco. (+)-cis-Abienol inhibits hyphal growth of P. nicotianae [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (Z)-Abienol. CAS No. 17990-16-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-121999.
cis-ACBD
cis-ACBD is a potent and selective inhibitor of the high-affinity, Na + -dependent plasma membrane glutamate transporter. cis-ACBD is a glutamate reuptake inhibitor. cis-ACBD also acts as linear competitive inhibitor of the uptake of D-[3H]aspartate [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: cis-1-Aminocyclobutane-1,3-dicarboxylic acid. CAS No. 73550-55-7. Pack Sizes: 2 mg. Product ID: HY-100616.
Cisapride
Cisapride (R 51619) is an orally active 5-HT 4 receptor agonist with an EC 50 value of 140 nM. Cisapride is a hERG blocker with an IC 50 value of 9.4 nM. Cisapride is a gastroprokinetic agent that stimulates gastrointestinal motor activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 51619; (±)-Cisaprid. CAS No. 81098-60-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14149.
Cisatracurium besylate
Cisatracurium besylate (51W89) is a nondepolarizing neuromuscular blocking agent, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 51W89 besylate; Cisatracurium besilate. CAS No. 96946-42-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-13596.
cis,cis-Muconic acid
cis,cis-Muconic acid, a metabolic intermediate of Klebsiella pneumonia , can be converted to adipic acid and terephthalic acid, which are important monomers of synthetic polymers. cis,cis-Muconic acid is also a biochemical material that can be used for the production of various plastics and polymers and is particularly gaining attention as an adipic acid precursor for the synthesis of nylon-6,6 [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1119-72-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W000800.
cis-Epoxysuccinic acid
cis-Epoxysuccinic acid is a succinate receptor (SUCNR1/GPR91) agonist. cis-Epoxysuccinic acid inhibits cAMP levels with an EC50 value of 2.7 ?M. cis-Epoxysuccinic acid can be used for the research of cardiovascular system[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 16533-72-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-125791.
cis-?Jasmone
Cis-Jasmone is a plant-derived natural product. Cis-Jasmone is constitutively released by many flowers and sometimes by leaves as an attractant for pollinators or as a chemical cue for host location by insect flower herbivores. Cis-Jasmone treatment of crop plants not only induces direct defense against herbivores, but also induces indirect defense by releasing VOCs that attract natural enemies [1]. Uses: Scientific research. Group: Natural products. CAS No. 488-10-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N7058.
cis-Nerolidol
cis-Nerolidol is a sesquiterpene alcohol that can be found in various plants. cis-Nerolidol exhibits antioxidant and antibacterial activities. cis-Nerolidol can also potentiate the action of antibiotics [1]. Uses: Scientific research. Group: Natural products. CAS No. 3790-78-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N1944A.
(-)-cis-Permethrin
(-)-cis-Permethrin is a pyrethroid insecticide widely used to control many common pests [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-cis-NRDC-143. CAS No. 54774-46-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-B0887D.
cis-Piperidine-2,3-dicarboxylic acid
Cis-piperidine-2,3-dicarboxylic acid is a non-specific antagonist of NMDA, AMPA and kainate ionotropic receptors and a partial agonist for NMDA receptors. Cis-piperidine-2,3-dicarboxylic acid can be used in blocking general excitatory synaptic transmissions [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 46026-75-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121964.
Cisplatin
Cisplatin (CDDP) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: cis-Platinum; CDDP; cis-Diaminodichloroplatinum. CAS No. 15663-27-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17394.
cis-Resveratrol
cis-Resveratrol exhibits signifcant antiviral activity. cis-Resveratrol inhibits enteroviruses with IC 50 s of 12.2 μM and 37.6 μM for coxsackievirus B3 (CVB3) and enterovirus 71 (EV71), respectively [1]. Uses: Scientific research. Group: Natural products. CAS No. 61434-67-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16561A.
cis-Urocanic acid
cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity ( K d =4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (Z)-Urocanic acid; cis-UCA. CAS No. 7699-35-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-113008A.
cis-Vaccenic acid
cis-Vaccenic acid, the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate [1] , acts a potential fetal hemoglobin inducer [2]. Uses: Scientific research. Group: Natural products. CAS No. 506-17-2. Pack Sizes: 25 mg (1.77 M * 0.05 mL in Ethanol); 50 mg (1.77 M * 0.1 mL in Ethanol); 100 mg (1.77 M * 0.2 mL in Ethanol). Product ID: HY-113427A.
cis-Zeatin
cis-Zeatin is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 32771-64-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W414851.
Citalopram
Citalopram is a racemate mixture of the active S(+)-enantiomer (Escitalopram; HY-14258) and R(-)-enantiomer. Citalopram is an orally active selective serotonin reuptake inhibitor (SSRI). Citalopram is an antidepressant and enhances serotoninergic neurotransmission [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 59729-33-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-121203.
Citalopram hydrobromide
Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI). Citalopram hydrobromide inhibits 5-HT uptake into synaptosomes with an IC 50 of 1.8 nM. Citalopram hydrobromideinhibits the 5-HT uptake in rabbit blood platelets with an IC 50 of 14 nM. Antidepressant effect [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Citalopram hydrobromide; Lu 10-171. CAS No. 59729-32-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1287.
Citarinostat
Citarinostat (ACY241) is a second generation potent, orally active and high-selective HDAC6 inhibitor with an IC 50 of 2.6 nM (IC 50 s of 35 nM, 45 nM, 46 nM and 137 nM for HDAC1, HDAC2, HDAC3 and HDAC8, respectively). Citarinostat has anticancer effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACY241. CAS No. 1316215-12-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15994.
CITCO
CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC 50 of 49?nM over pregnane X receptor (PXR) , and no activity on other nuclear receptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 338404-52-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103244.
Citicoline
Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Cytidine diphosphate-choline; CDP-Choline; Cytidine 5'-diphosphocholine. CAS No. 987-78-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0739.
Citicoline sodium
Citicoline sodium is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline sodium inhibits reactive oxygen species (ROS) and apoptosis. Citicoline sodium can be used for neurological disease and hearing loss study [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cytidine diphosphate-choline sodium; CDP-Choline sodium; Cytidine 5'-diphosphocholine sodium. CAS No. 33818-15-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0739A.
Citraconic acid
Citraconic acid belongs to the class of organic compounds known as methyl-branched fatty acids. Uses: Scientific research. Group: Natural products. Alternative Names: Methylmaleic acid. CAS No. 498-23-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-113298.
Citraconic anhydride
Citraconic anhydride (Methylmaleic anhydride) is a derivative of maleic anhydride. Citraconic anhydride is utilized to block the proteins amino groups reversibly, stabilizes certain enzymes and improves their catalytic performance, or to reverse the effects of formalin fixation in tissue sections. Citraconic anhydride is irritating for skin and eyes [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Methylmaleic anhydride. CAS No. 616-02-4. Pack Sizes: 1 g. Product ID: HY-78035.
Citral
Citral is an orally active monoterpene compound in lemon grass essential oil and a natural ALDH1A inhibitor, which can induce apoptosis and cycle arrest in breast cancer cell lines, and has analgesic, anti-injurious and anti-inflammatory effects [2][3]. Uses: Scientific research. Group: Natural products. CAS No. 5392-40-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N7083.
Citral (Standard)
Citral (Standard) is the analytical standard of Citral. This product is intended for research and analytical applications. Citral is an orally active monoterpene compound in lemon grass essential oil and a natural ALDH1A inhibitor, which can induce apoptosis and cycle arrest in breast cancer cell lines, and has analgesic, anti-injurious and anti-inflammatory effects [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 5392-40-5. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N7083R.
Citrate synthase
Citrate synthase is responsible for catalyzing the first reaction of the citric acid cycle: the condensation of acetyl-CoA and oxaloacetate to form citrate. Citrate synthase is localized within eukaryotic cells in the mitochondrial matrix [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9027-96-7. Pack Sizes: 250 U; 500 U; 1000 U. Product ID: HY-P2739.
Citric acid
Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 77-92-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N1428.
Citric acid-13C6
Citric acid-13C6 is the 13C-labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 287389-42-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N1428S1.
Citric acid-d4
Citric acid-d 4 is the deuterium labeled Citric acid. Citric acid is a weak organic tricarboxylic acid found in citrus fruits. Citric acid is a natural preservative and food tartness enhancer. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 147664-83-3. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-N1428S.
Citric acid monohydrate
Citric acid monohydrate is a natural preservative and food tartness enhancer. Citric acid monohydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid monohydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid monohydrate causes renal toxicity in mice [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 5949-29-1. Pack Sizes: 5 g; 10 g. Product ID: HY-N1428A.
Citric acid (standard)
Citric acid (Standard) is the analytical standard of Citric acid. This product is intended for research and analytical applications. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 77-92-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1428R.
Citric acid tripotassium hydrate
Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) is the major active ingredient of Garcinia cambogia. Hydroxycitric acid tripotassium hydrate competitively inhibits ATP citrate lyase with weight loss benefits. Hydroxycitric acid tripotassium hydrate effective inhibits stones formation and also inhibits HIF , and has antioxidation, anti-inflammation and anti-tumor effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Potassium citrate monohydrate. CAS No. 6100-5-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W009156.
Citric acid (tripotassium hydrate) (Standard)
Citric acid (tripotassium hydrate) (Standard) is the analytical standard of Citric acid (tripotassium hydrate). This product is intended for research and analytical applications. Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) is the major active ingredient of Garcinia cambogia. Hydroxycitric acid tripotassium hydrate competitively inhibits ATP citrate lyase with weight loss benefits. Hydroxycitric acid tripotassium hydrate effective inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation and anti-tumor effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 6100-5-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W009156R.
Citric acid trisodium
Citric acid trisodium is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium causes renal toxicity in mice [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Sodium citrate; Trisodium citrate anhydrous. CAS No. 68-04-2. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-B2201.
Citrinin
Citrinin (NSC 186) is a mycotoxin that causes food contamination and has different toxic effects. Citrinin is an effective oral anticancer agent. Citrinin has various regulatory effects on mouse immune system, including regulating the number of immune cells, inducing apoptosis and autophagy of immune cells, altering toll-like receptor expression and cytokine production. Citrinin can induce oxidative stress and lead to early apoptosis of oocytes. Low doses of Citrinin have neuroprotective effects against glutamate-induced excitotoxicity in rat cortical neurons. In addition, Citrinin also has antibacterial activity [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 186. CAS No. 518-75-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6746.
Citronellal
Citronellal is a monoterpenea from the essential oils in various aromatic species of plants, with depressant, and antinociceptive properties. Citronellal attenuates mechanical nociception, mediated in part by the NO-cGMP-ATP-sensitive K ? channel pathway [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 106-23-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N7126.
Citronellol
Citronellol ((±)-Citronellol) is an orally active inducer of apoptosis. Citronellol can prevent oxidative stress, mitochondrial dysfunction, and apoptosis in the SH-SY5Y cell Parkinson's disease model induced by 6-OHDA by regulating the ROS-NO , MAPK/ERK , and PI3K/Akt signaling pathways. Citronellol can induce necroptosis in human lung cancer cells through the TNF-α pathway and accumulation of ROS. Citronellol can reduce the levels of LC-3 and p62 to regulate the autophagy pathway, inhibit oxidative stress and neuroinflammation, and thus have neuroprotective effects on Parkinson's rats. Citronellol exhibits anti- fungal activity against Trichophyton rubrum by inhibiting ergosterol synthesis [2] [4] [6] [7]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Citronellol; (±)-β-Citronellol. CAS No. 106-22-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W010201.
Citronellyl acetate
Citronellyl acetate is a monoterpene product of the secondary metabolism of plants, with antinociceptive activity. Citronellyl acetate exhibits pro-apoptotic activity in human hepatoma cells. Citronellyl acetate shows fungicidal, larvicidal, bactericidal and repelling/insecticidal effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 150-84-5. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-N7144A.
Cixiophiopogon A
Cixiophiopogon A, a steroidal glycoside, obtained from the tuberous roots of Ophiopogon japonicus (Liliaceae) [1]. Uses: Scientific research. Group: Natural products. CAS No. 288143-27-1. Pack Sizes: 5 mg. Product ID: HY-N2175.
Cixutumumab
Cixutumumab (IMC-A12) is a human anti- IGF-1R monoclonal antibody with high affinity that inhibits ligand-dependent receptor activation and downstream signaling. Cixutumumab also mediates the internalization and degradation of IGF-IR. Cixutumumab shows broad-spectrum anti-tumour activity and can be used in studies of cancers such as lung cancer, malignancies, leukaemia, non-small cell lung cancer and prostate cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IMC-A12; NSC742460. CAS No. 947687-12-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99189.
CJ-13,610
CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC 50 of about 70 nM [1]. PMNL: polymorphonuclear leukocytes; AA: arachidonic acid. Uses: Scientific research. Group: Signaling pathways. CAS No. 179420-17-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106200.
CK2/ERK8-IN-1
CK2/ERK8-IN-1 is a dual casein kinase 2 (CK2) (Ki of 0.25 μM) and ERK8 (MAPK15, ERK7) inhibitor with IC50s of 0.50 ?M. CK2/ERK8-IN-1 also binds to PIM1, HIPK2 (homeodomain-interacting protein kinase 2), and DYRK1A with Kis of 8.65 μM, 15.25 μM, and 11.9 μM, respectively. CK2/ERK8-IN-1 has pro-apoptotic efficacy[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1085822-09-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135906.
CK-636
CK-636 is a cell permeable inhibitor of Arp2/3 complex, that could inhibit actin polymerization, with IC50 values of 4 ?M, 24 ?M and 32 ?M for human, fission yeast and bovine, respectively. CK636 blocks cell migration. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CK-0944636. CAS No. 442632-72-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15892.
CK-666
CK-666 is a cell-permeable actin-related protein Arp2/3 complex inhibitor (IC50=12 ?M). CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 442633-00-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16926.
CK7
CK7, a Cdk2/9 inhibitor, can be used for the synthesis of Nek1 inhibitor BSc5231 and BSc5367 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 507487-89-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103646.
CK-869
CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor, with an IC50 of 7 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 388592-44-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16927.
CKI-7 free base
CKI-7 free base is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC 50 of 6 μM and a K i of 8.5 μM. CKI-7 free base is a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK , ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 free base has a much weaker effect on casein kinase II and other protein kinases [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120615-25-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133028.
c-Kit-IN-5-1
c-Kit-IN-5 is potent inhibitor of c-Kit, with IC50s of 22 nM and 16 nM in kinase assay and cell assay, respectively. c-Kit-IN-5 shows more than 200-fold selectivity for c-Kit over KDR, p38, Lck, and Src. c-Kit-IN-5 also exhibits desirable pharmacokinetic properties[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1003311-62-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-18302.
CKK-E12
CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1432494-65-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134781.
CL097
CL097, a potent TLR7 and TLR8 agonist, induces pro-inflammatory cytokines in macrophages[1]. CL097 induces NADPH oxidase priming, resulting in an increase of the fMLF-stimulated ROS production[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1026249-18-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128799.
CL 218872
CL 218872 is a selective and orally active benzodiazepine of α1 subunit-containing GABA A receptor with a K i of 130 nM. CL 218872 exerts anxiolytic and anticonvulsant in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66548-69-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103505.
CL2A-SN-38
CL2A-SN-38 is a agent-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody agent conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A-SN-38 uses hydrolyzable linker to deliver active agents within tumor cells and in the tumor microenvironment, resulting in bystander effects[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1279680-68-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128946.
CL 316243
CL316243 is a highly potent selective β3-adrenoceptor agonist with a EC 50 of 3 nM, but is an extremely poor to β1/2- receptors [1].CL316243 is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate [2]. CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 138908-40-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116771A.
CL 316243 free acid
CL316243 free acid is a highly potent selective β3-adrenoceptor agonist with a EC 50 of 3 nM, but is an extremely poor to β1/2- receptors. CL316243 free acid is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 free acid has the potential for the treatment obesity, diabetes and urge urinary incontinence [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 183720-02-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-116771.
CL-82198
CL-82198 is a selective inhibitor of MMP-13. CL-82198 binds to the entire S1 pocket of MMP-13, which is the basis for its selectivity towards MMP-13 and the lack of inhibitory activities against other MMPs[1][2]. CL-82198 is a pharmacologic treatment for preventing osteoarthritis (OA) progression[4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 307002-71-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100359.
Cladosporin
Cladosporin is a fungal metabolite produced in good yield in the mycelium of Cladosporium cladosporioid. Cladosporin completely inhibits growth of severa dermatophytes on agar medium at a concentration of 75 μg/mL [1]. Uses: Scientific research. Group: Natural products. CAS No. 35818-31-6. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-136767.
Cladribine
Cladribine (2-Chloro-2-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple sclerosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Chloro-2-deoxyadenosine; CldAdo; 2CdA. CAS No. 4291-63-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13599.
Cl-amidine hydrochloride
Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 ?M, 6.2 ?M and 5.9 ?M for PAD1, PAD3, and PAD4, respectively. Cl-amidine hydrochloride induces apoptosis in cancer cells. Cl-amidine hydrochloride induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1373232-26-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100574A.
Clamikalant sodium
Clamikalant sodium (HMR 1098) is an ATP-sensitive potassium ( K ATP ) channel blocker. Clamikalant sodium can be used for the research of arrhythmia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HMR 1098. CAS No. 261717-22-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15208.
Clarithromycin
Clarithromycin has a broad spectrum of antimicrobial activity. Clarithromycin inhibits the CYP3A4 -catalyzed triazolam alpha-hydroxylation with the IC 50 ( K i ) value of 56 (43) μM [2]. Clarithromycin significantly inhibits the HERG potassium current [3].Clarithromycin affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81103-11-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-17508.
Clarithromycin (Standard)
Clarithromycin (Standard) is the analytical standard of Clarithromycin. This product is intended for research and analytical applications. Clarithromycin has a broad spectrum of antimicrobial activity. Clarithromycin inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with the IC50 (Ki) value of 56 (43) μM [2]. Clarithromycin significantly inhibits the HERG potassium current [3].Clarithromycin affects the autophagic flux by impairing the signaling pathway linking hERG1 and PI3K [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81103-11-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-17508R.
Clascoterone
Clascoterone (Cortexolone 17 alpha-propionate;Cortexolone 17α-propionate;CB-03-01) is a new topical and peripherally selective androgen antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cortexolone 17 alpha-propionate; Cortexolone 17α-propionate; CB-03-01. CAS No. 19608-29-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-13331.