MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Coronaridine | Coronaridine, an iboga type alkaloid, inhibits the wnt signaling pathway by decreasing β-catenin expression [1]. Uses: Scientific research. Group: Natural products. CAS No. 467-77-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-121118. |  |
| Coronatine | Coronatine is a plant growth regulator that mimicks the jasmonic acid-isoleucine conjugate (JA-Ile), targets the jasmonic acid receptor COI1, activates the jasmonic acid signaling pathway, thereby inhibiting salicylic acid (SA)-dependent defense responses. Coronatine antagonizes the stomatal closure, induces plant cell necrosis and chlorosis, interfers with plant hormone balance, thereby promoting pathogen infection [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 62251-96-1. Pack Sizes: 1 mg. Product ID: HY-N11420. | |
| Corosolic acid | Corosolic acid (Colosolic acid) isolated from the fruit of Cratoegus pinnatifida var. psilosa, was reported to have anticancer activity. Corosolic acid induces cancer cell apoptosis [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Colosolic acid. CAS No. 4547-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0280. | |
| Cort108297 | Cort108297 is a specific glucocorticoid receptor ( GR ) antagonist. Cort108297 has a high affinity for GRs with a K i of 0.45 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1018679-79-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15710. | |
| Corticosterone | Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab -mediated AMPAR membrane traffic via SGK -induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 17-Deoxycortisol; 11β,21-Dihydroxyprogesterone; Kendall's compound B. CAS No. 50-22-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B1618. | |
| Cortisol sulfate sodium | Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate sodium is a specific ligand for intracellular transcortin [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Cortisol 21-sulfate sodium. CAS No. 1852-36-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N8460A. | |
| Cortisone | Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations [1] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 17-Hydroxy-11-dehydrocorticosterone; Kendall's compound E. CAS No. 53-06-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17461. | |
| Cortisone-13C3 | Cortisone- 13 C 3 is the 13 C-labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 2350278-95-2. Pack Sizes: 100 μg (275.16 μM * 1 mL in Methanol). Product ID: HY-17461S. | |
| Cortisone acetate | Cortisone acetate (Cortisone 21-acetate), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acetate acts as an immunosuppressant and anti-inflammatory agent. Cortisone acetate can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations [1] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Cortisone 21-acetate. CAS No. 50-04-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-17461A. | |
| Cortisone acetate (Standard) | Cortisone acetate (Standard) is the analytical standard of Cortisone acetate. This product is intended for research and analytical applications. Cortisone acetate (Cortisone 21-acetate), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acetate acts as an immunosuppressant and anti-inflammatory agent. Cortisone acetate can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations [1] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Cortisone 21-acetate (Standard). CAS No. 50-04-4. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17461AR. | |
| Cortisone (Standard) | Cortisone (Standard) is the analytical standard of Cortisone. This product is intended for research and analytical applications. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations [1] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 17-Hydroxy-11-dehydrocorticosterone(Standard); Kendall's compound E (Standard). CAS No. 53-06-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-17461R. | |
| Cortistatin-14 | Cortistatin-14 is a neuropeptide that shares structural similarities with somatostatin, working by binding to somatostatin receptors ( sst1 - sst5 ). Cortistatin-14 (TFA) has anticonvulsant, neuroprotective effects, and significant anti-inflammatory properties [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 186901-48-4. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1932. | |
| Cortodoxone | Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation[1][2]. Uses: Scientific research. Group: Natural products. Alternative Names: 11-Deoxycortisol; cortexolone; Reichstein's substance S. CAS No. 152-58-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-77839. | |
| Corydaline | Corydaline ((+)-Corydaline), an isoquinoline alkaloid isolated from Corydalis yanhusuo , is an AChE inhibitor with an IC 50 of 226 μM. Corydaline is a μ-opioid receptor ( K i of 1.23 μM) agonist and inhibits enterovirus 71 (EV71) replication ( IC 50 of 25.23 μM). Corydaline has anti-angiogenic, anti-allergic and gastric-emptying and antinociceptive activities [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Corydaline; Corydalin. CAS No. 518-69-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0923. | |
| Corylin | Corylin is an orally active flavonoid anti-inflammatory and osteogenic agent that inhibits IL-6-induced STAT3 promoter activity and STAT3 phosphorylation. Corylin also has anticancer, antiatherosclerotic, and ameliorating activity in hyperlipidemia and insulin resistance, inducing adipocyte browning and lipolysis through SIRT1 or β3-AR-dependent pathways [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 53947-92-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0236. | |
| (-)-Corynoxidine | (-)-Corynoxidine is an acetylcholinesterase inhibitor with an IC 50 value of 89.0 μM, isolated from the aerial parts of Corydalis speciosa [1]. (-)-Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains in different degrees [2]. Uses: Scientific research. Group: Natural products. CAS No. 57906-85-1. Pack Sizes: 5 mg. Product ID: HY-N7010. | |
| Corynoxine | Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria rhynchophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway [1]. Uses: Scientific research. Group: Natural products. CAS No. 6877-32-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0901. | |
| Cosfroviximab | Cosfroviximab (c13C6-FR1) is a mouse/human chimeric monoclonal antibody against Ebola virus glycoprotein (EBOV-GP) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: c13C6-FR1. CAS No. 1792982-57-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99832. | |
| Cosibelimab | Cosibelimab (CK-301; TG-1501) is a high-affinity, fully human PD-L1 -blocking monoclonal antibody that binds PD-L1 and blocks its interaction with PD-1. Cosibelimab has a functional Fc domain and is capable of inducing ADCC and complement-dependent cytotoxicity (CDC)-mediated killing of PD-L1 + cell lines, including lymphoma cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CK-301; TG-1501. CAS No. 2216751-26-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99833. | |
| Costunolide | Costunolide ((+)-Costunolide) is a naturally occurring sesquiterpene lactone, with antioxidative, anti-inflammatory, antiallergic, bone remodeling, neuroprotective, hair growth promoting, anticancer, and antidiabetic properties. Costunolide can induce cell cycle arrest and apoptosis on breast cancer cells [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Costunolide; Costus lactone. CAS No. 553-21-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0036. | |
| Cotadutide | Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC 50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D) [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: MEDI0382. CAS No. 1686108-82-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2231. | |
| COTI-2 | COTI-2, an anti-cancer agent with low toxicity, is an orally available third generation activator of p53 mutant forms. COTI-2 acts both by reactivating mutant p53 and inhibiting the PI3K/AKT/mTOR pathway. COTI-2 induces apoptosis in multiple human tumor cell lines. COTI-2 exhibits antitumor activity in HNSCC through p53-dependent and -independent mechanisms. COTI-2 converts mutant p53 to wild-type conformation[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1039455-84-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19896. | |
| Cotinine | Cotinine ((-)-Cotinine) is an orally active alkaloid found in tobacco and is the primary metabolite of nicotine. Cotinine is metabolized by CYP2A13 into trans-3'-hydroxycotinine. Cotinine is used as a biomarker to measure exposure to tobacco smoke components. Cotinine has vasodepressor activity. The mixture of cotinine and nicotine (Nicotine) has antiproliferative activity against pterygium. (S)-(-)-Cotinine activates nicotinic acetylcholine receptors ( nAChR ) in a calcium-dependent manner, leading to the release of dopamine (Dopamine, HY-B0451). Cotinine ((-)-Cotinine) is used in research related to cardiovascular and inflammatory diseases [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Cotinine; (S)-Cotinine; NIH-10498. CAS No. 486-56-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B1178. | |
| Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:19) | Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:19), an antimicrobial agent, is a Trimethoprim and Sulfamethoxazole mixture. The ratio of Trimethoprim to Sulfamethoxazole in the combination mixture is 1?:?19[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 8064-90-2. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-141619A. | |
| Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:5) | Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:5) is an active compound for toxoplasmic encephalitis inhibition, as well as inhibition in protozoan and bacterial infections[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 8064-90-2. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-141619. | |
| Cottonseed oil | Cottonseed oil is a cooking oil extracted from the seeds of cotton plants and has been generally considered the most insecticidal of vegetable oils. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 8001-29-4. Pack Sizes: 100 mL; 500 mL. Product ID: HY-Y1887. | |
| Coumarin | Coumarin is a potent and orally active anti-inflammatory agent. Coumarin shows an antinociceptive effect. Coumarin shows antibacterial, antifungal and anticancer activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 91-64-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0709. | |
| Coumarin 106 | Coumarin 106 (Coumarin 478) is a dipolar laser dye. Coumarin 106 is an inhibitor of AChE and BChE. Coumarin 106 displays mixed-type AChE inhibition with a pIC 50 =4.97 and K i =2.36 μM. Coumarin 106 inhibits BChE with slightly lower potency ( pIC 50 =4.56) [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Coumarin 478. CAS No. 41175-45-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W324391. | |
| Coumarin 343 | Coumarin 343 (C343) is a hydrophilic fluorescent probe for the micro water pool. λem is approximately 425 nm andλem is approximately from 425 nm to 550 nm by RF-1500 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C343. CAS No. 55804-65-4. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W267364. | |
| Coumarin-3-carboxylic Acid | Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Oxochromene-3-carboxylic acid. CAS No. 531-81-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W027968. | |
| Coumarin 6 | Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λ exc =450 nm, λ em =505 nm) [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 38215-36-0. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-N7131. | |
| Coumermycin A1 | Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. Coumermycin A1 shows anti-orthopoxvirus activity. Uses: Scientific research. Group: Natural products. CAS No. 4434-5-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7452. | |
| Coumestrol | Coumestrol, a phytoestrogen present in soybean products, exhibits activities against cancers, neurological disorders, and autoimmune diseases. It suppresses proliferation of ES2 cells with an IC 50 of 50 μM. Uses: Scientific research. Group: Natural products. CAS No. 479-13-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2335. | |
| COX-2-IN-18 | COX-2-IN-18 (Compound 3) is a potent inhibitor of COX-2. COX-2-IN-18 possesses good COX-2 inhibitory activity ( IC 50 = 0.775 μM) compared to the reference agent, Celecoxib ( IC 50 = 0.153 μM). COX-2-IN-18 has the potential for the research of cancer diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1038061-96-9. Pack Sizes: 5 mg. Product ID: HY-147794. | |
| CP-10 | CP-10 is a PROTAC connected by ligands for Cereblon and CDK , with highly selective, specific, and remarkable CDK6 degradation ( DC 50 =2.1 nM). It inhibits proliferation of several haematopoietic cancer cells with impressive potency including multiple myeloma, and can still degrades mutated and overexpressed CDK6 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2366268-80-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-125835. | |
| CP-100356 hydrochloride | CP-100356 hydrochloride is an orally active dual MDR1 (P-gp)/BCRP inhibitor, with an IC50s of 0.5 and 1.5 μM for inhibiting MDR1-mediated Calcein-AM transport and BCRP-mediated Prazosin transport, respectively. CP-100356 hydrochloride is also a weak inhibitor of OATP1B1 (IC50=?66 μM). CP-100356 hydrochloride is devoid of inhibition against MRP2 and major human P450 enzymes (IC50>15 μM)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 142715-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108347. | |
| CP-105696 | CP-105696 is a potent and selective Leukotriene B4 Receptor antagonist, with an IC50 of 8.42 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pfizer 105696. CAS No. 158081-99-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19193. | |
| CP 154526 hydrochloride | CP 154526 hydrochloride is a potent, brain-penetrant and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist with a K i of 2.7 nM. CP 154526 hydrochloride shows selective for CRF1 over CRF2 (K i=>10 μM). CP 154526 hydrochloride has anxiolytic activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 257639-98-8. Pack Sizes: 5 mg. Product ID: HY-12129. | |
| CP21R7 | CP21R7 is potent GSK-3? inhibitor, with an IC50 of 1.8 nM; CP21R7 also shows inhibitory activitiy against PKC?, with an IC50 of 1900 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP21. CAS No. 125314-13-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100207. | |
| CP-24879 hydrochloride | CP-24879 (hydrochloride) is a potent, selective and combined delta5D/delta6D inhibitor. CP-24879 (hydrochloride) can significantly reduce intracellular lipid accumulation and inflammatory injury in hepatocytes. CP-24879 (hydrochloride) exhibits superior antisteatotic and anti-inflammatory actions in fat-1 and ?-3-treated hepatocytes, and can be used for non-alcoholic steatohepatitis research[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 10141-51-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115319. | |
| CP26 | CP26 is a small molecule inhibitor of protein dislocation from the ER lumen to the cytosol. CP26 targets the Hrd1 complex, inhibits ERAD, and induces ER stress [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 500285-30-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-49116. | |
| CP-31398 dihydrochloride | CP-31398 dihydrochloride stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1217195-61-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18343A. | |
| CP-316819 | CP 316819 is a potent glycogen phosphorylase (GPase) inhibitor with antihyperglycemic effect (IC50 values are 17 and 34 nM against human skeletal muscle glycogen phosphorylase (huSMGPa) and liver glycogen phosphorylase (huLGPa) respectively).CP 316819 causes glycogen accumulation under normoglycemic conditions but permits glycogen utilization when glucose concentrations are low.CP-316819 prevents neuronal cell death and maintains brain electrical currents[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GPi 819. CAS No. 186392-43-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108615. | |
| CP 339818 hydrochloride | CP 339818 hydrochloride is a nonpeptide and selective Kv1.3 ( IC 50 value of ~200 nM) and Kv1.4 channels blocker. CP 339818 hydrochloride is a significantly less potent blocker of Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2. CP 339818 hydrochloride potently blocks the C-type inactivated conformation of Kv1.3 and suppresses T cell activation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 478341-55-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108574. | |
| CP-346086 | CP-346086 is a potent and orally active microsomal triglyceride transfer protein (MTP) inhibitor, with an IC50 of 2.0 nM for human and rodent MTP. CP-346086 can lower plasma cholesterol and triglycerides in vivo[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 186390-48-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113955. | |
| CP-465022 | CP-465022 is a potent, and selective noncompetitive AMPA receptor antagonist with anticonvulsant activity. CP-465022 is against Kainate-induced response with an IC 50 of 25 nM in rat cortical neurons. CP-465022 provides a new tool to investigate the role of AMPA receptors in physiological and pathophysiological processes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199655-36-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18663. | |
| CP-547632 hydrochloride | CP-547632 hydrochloride is an orally active, ATP-competitive and potent VEGFR-2 and FGF kinases inhibitor with IC50s of 11 nM and 9 nM, respectively. CP-547632 hydrochloride is selective for VEGFR2 and bFGF over EGFR, PDGFR?, and related tyrosine kinases (TKs). CP-547632 hydrochloride has antitumor efficacy[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 252003-71-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13302B. | |
| CP-640186 | CP-640186 is an orally active and cell-permeable Acetyl-CoA carboxylase ( ACC ) inhibitor with IC 50 s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 can also stimulate muscle fatty acid oxidation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 591778-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15259. | |
| CP-640186 hydrochloride | CP-640186 hydrochloride is an orally active and cell-permeable Acetyl-CoA carboxylase ( ACC ) inhibitor with IC 50 s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 hydrochloride can also stimulate muscle fatty acid oxidation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 591778-70-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15259A. | |
| CP-673451 | CP-673451 is a potent and selective inhibitor of PDGFR with IC50s of 10 and 1 nM for PDGFR? and PDGFR?, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 343787-29-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12050. | |
| CP-724714 | CP-724714 is a potent, selective and orally active ErbB2 (HER2) tyrosine kinase inhibitor, with an IC 50 of 10 nM. CP-724714 displays a marked selectivity against EGFR kinase (IC 50 =6400 nM). CP-724714 potently inhibits ErbB2 receptor autophosphorylation in intact cells. Antitumor activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 383432-38-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14674. | |
| CP-775146 | CP-775146 is a selective PPARα agonist that binds strongly to the PPARα ligand. CP-775146 efficiently alleviates obesity-induced liver damage, prevents lipid accumulation by activating the liver fatty acid β-oxidation pathway [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 702680-17-9. Pack Sizes: 5 mg. Product ID: HY-108571. | |
| CP-809101 hydrochloride | CP-809101 hydrochloride is a potent and highly selective 5-HT 2C receptor agonist, with pEC 50 s of 9.96, 7.19 and 6.81 M for human 5HT 2C , 5HT 2B and 5HT 2A receptor. CP-809101 hydrochloride inhibits conditioned avoidance responding in rats and antagonizes both PCP (phencyclidine hydrochloride)- and d-amphetamine-induced hyperactivity. CP-809101 hydrochloride also reduces food and nicotine dependence in rats, can be used in studies of antipsychotic and nicotine dependence [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1215721-40-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15543A. | |
| CP-91149 | CP-91149 is a GP (glycogen phosphorylase) inhibitor. CP-91149 promotes glycogen resynthesis, but not its overaccumulation. CP-91149 has the potential for Type II (insulin-dependent) diabetes study [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 186392-40-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13525. | |
| CP 93129 dihydrochloride | CP 93129 dihydrochloride is a potent 5HT 1B receptor agonist. CP 93129 dihydrochloride has the potential for parkinson's disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 879089-64-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101357A. | |
| CP94253 hydrochloride | CP94253 hydrochloride is a potent and selective agonist of 5-HT 1B receptor ( K i = 2 nM in a radioligand binding assay).K i values for 5-HT 1A , 5-HT 1D , 5-HT 1C and 5-HT 2 receptors are 89, 49, 860, and 1600 nM respectively [1]. CP94253 hydrochloride is centrally active upon systemic administration in vivo [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 845861-39-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103151. | |
| CPCCOEt | CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of metabotropic glutamate receptor 1b (mGluR1b) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179067-99-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101356. | |
| CPD-1224 | CPD-1224 is an orally effective ALK inhibitor, a derivative of an ALK inhibitor that connects to the cereblon ligand. CPD-1224 targets the EML4-ALK oncogenic fusion protein and degrades both ALK and the mutant forms L1196M/G1202R. CPD-1224 can slow down tumor growth[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2891620-68-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153386. | |
| CPDA | CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1415834-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18685. | |
| C-Peptide 1 (rat) | C-Peptide 1 (rat), a peptide, is aβ-catenin/GSK-3β activator. C-Peptide 1 (rat) can regulate the Wnt/β-catenin signaling pathway. C-Peptide 1 (rat) can be used for the research of cancer [1]. Uses: Scientific research. Group: Peptides. CAS No. 41475-27-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4858. | |
| CPG-52364 | CPG-52364 (compound 2) is a TLR9 antagonist. CPG-52364 inhibits the HEK293-hTLR9 cell with an IC50 value of 4.6 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1093135-60-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-120538. | |
| C-Phycocyanin | C-phycocyanin (C-PC) is a protein pigment which is also widely used as an excellent nutrient supplement for human beings. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: C-PC. CAS No. 11016-15-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1025. | |
| CPI-1612 | CPI-1612 is a highly potent, orally active EP300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 of 8.1 nM for EP300 HAT. CPI-1612 has an anticancer activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2374971-81-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136285. | |
| CPI-203 | CPI-203 is a novel potent, selective and cell permeable inhibitor of BET bromodomain, with an IC50 value of appr 37 nM (BRD4 ?-screen assay). Uses: Scientific research. Group: Signaling pathways. CAS No. 1446144-04-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15846. | |
| CPI-455 | CPI-455 is a specific, pan- KDM5 inhibitor with an IC 50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1628208-23-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100421. | |
| CPI-637 | CPI-637 is a selective and potent CBP/EP300 bromodomain inhibitor with IC50 values of 0.03 ?M, 0.051 ?M and 11.0 ?M for CBP, EP300 and BRD4 BD-1, respectively, and an EC50 of 0.3 ?M for CBP[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1884712-47-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100482. | |
| CPK20 | CPK20 is a potent and highly selective KCNT1 channel blocker, and CPK20 can be used in the study of epilepsy [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2397708-22-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162549. | |
| CPM | CPM is a maleimide derivative, acting as a blue fluorescent thiol-reactive dye (excitation/emission maxima of 387/463 nm) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 76877-33-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D0069. | |
| CPPG | CPPG ((RS)-CPPG) is a potent group II/III mGlu receptors antagonist. CPPG exhibits some selectivity (approximately 20 fold) for group III ( IC 50 =2.2 nM) over group II ( IC 50 =46.2 nM) mGlu receptors in the rat cerebral cortex. CPPG has weak effects at group I mGlu receptors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (RS)-CPPG. CAS No. 183364-82-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101333. | |
| CPS-11 | CPS-11 (N-(Hydroxymethyl)thalidomide) a Thalidomide (HY-14658) analogue, is a potent anti-cancer agent. CPS-11 inhibits NF-κB , activates NFAT , and repress cytokine expression through elevated ROS. CPS-11 exhibits a wider activity spectrum and higher potency against MM (multiple myeloma) cell lines [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-(Hydroxymethyl)thalidomide. CAS No. 145945-21-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-117987. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.