MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| DMPQ dihydrochloride | DMPQ dihydrochloride is a potent and selective inhibitor of human platelet-derived growth factor receptor β (PDGFRβ) with an IC 50 of 80 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1123491-15-5. Pack Sizes: 1 mg. Product ID: HY-108627. |  |
| DMT-2'-F-Bz-dA | DMT-2'-F-Bz-dA can be used in the synthesis of nucleotides and nucleic acids. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 136834-21-4. Pack Sizes: 250 mg; 1 g. Product ID: HY-W093086. | |
| DMTMM | DMTMM (4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride. CAS No. 3945-69-5. Pack Sizes: 25 g; 100 g. Product ID: HY-Y1168. | |
| D-myo-Inositol 1,4,5-trisphosphate tripotassium | D-myo-Inositol 1,4,5-trisphosphate tripotassium, a second messenger, elicits Ca 2+ mobilization. D-myo-Inositol 1,4,5-trisphosphate tripotassium inhibits the binding of phosphoinositide-specific phospholipase C-delta 1 (PLC-delta 1) to bilayer membranes composed of phosphatidylcholine (PC) and phosphatidylinositol 4,5-bisphosphate (PIP2) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Inositol 1,4,5-trisphosphate tripotassium; Ins(1,4,5)-P3 tripotassium. CAS No. 141611-11-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-150135B. | |
| DN5355 | DN5355 is a small molecule compound that targets amyloid β protein ( Aβ ) and hyperphosphorylated tau protein. DN5355 can inhibit the aggregation of Aβ and tau protein and disaggregate the formed Aβ and tau protein fibers. DN5355 can be used in the study of Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 937012-09-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-159083. | |
| DNA-PK Substrate | DNA-PK Substrate is a biological active peptide. (A substrate for DNA-dependent protein kinase (DNA-PK), phosphorylation. DNA-PK is essential for the repair of DNA double-strand breaks. This peptide corresponding to 11 - 24 amino acids of human p53 with threonine 18 and serine 20 changed to alanine is used as a substrate for the assay of DNA-PK activityPyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.). Uses: Scientific research. Group: Peptides. CAS No. 146064-85-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5429. | |
| DNA relaxation-IN-1 | DNA relaxation-IN-1 (compound 27) is a DNA Ligase 1 ( DNA Lig1 ) inhibitor, which inhibits DNA ligation and disrupts Lig Is DNA relaxation activity. DNA relaxation-IN-1 combined with Topotecan (HY-13768) exhibits a synergistic antiproliferative effect on colorectal cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2190506-29-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161152. | |
| DNase I, Bovine pancreas | DNase I (EC 3.1.21.1) is an enzyme that degrade DNA, it plays a key role in the cleavage of extracellular DNA is crucial for limiting the inflammatory response and maintaining homeostasis. Exogenous deoxyribonuclease shows beneficial effects in inflammatory diseases and cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DNase. CAS No. 9003-98-9. Pack Sizes: 50 mg; 100 mg. Product ID: HY-108882. | |
| DND-189 | DND-189, a low-pH fluorescent probe, is sensitive to neutral and low pH range. DND-189 can be used to measure the pH of acidic organelles [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 152584-38-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D1457. | |
| DNDI-6174 | DNDI-6174 is a cytochrome bc1 complex inhibitor with potent in vitro activity against a variety of Leishmania species. DNDI-6174 can reduce parasite burden in animal models of infection [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2868298-43-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162066. | |
| DNL343 | DNL343 is a potent, selective, orally active and brain-penetrant activator of eukaryotic initiation factor eIF2B. DNL343 inhibits the activity of the integrated stress response (ISR) in the central nervous system (CNS) and reverses neurodegeneration and neuroinflammation. DNL343 also prevents motor dysfunction and premature death in eIF2B loss-of-function (LOF) mutant mice. DNL343 can be used in the study of neurodegenerative diseases [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2278265-85-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149555. | |
| D-(-)-Norleucine | D-(-)-Norleucine is a leucine derivative [1]. Uses: Scientific research. Group: Peptides. Alternative Names: (R)-2-Aminohexanoic acid; (R)-Norleucine. CAS No. 327-56-0. Pack Sizes: 25 g; 100 g. Product ID: HY-41912A. | |
| D-Norvaline | D-Norvaline is a valine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 2013-12-9. Pack Sizes: 25 g. Product ID: HY-41309. | |
| DNP-PEG4-NHS ester | DNP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 858126-78-0. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-140614. | |
| DNQX | DNQX (FG 9041), a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist ( IC 50 s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FG 9041. CAS No. 2379-57-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15067. | |
| DO2A-tert-butyl ester | DO2A-tert-butyl ester is a bifunctional chelator ( BFC ) that can be used for the coupling of peptides and radionuclides. DO2A-tert-butyl ester can be used in the development of radionuclide imaging tracers [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 162148-48-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W283556. | |
| Dobutamine hydrochloride | Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 49745-95-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-15746. | |
| Docetaxal | Docetaxal (10-Acetyl docetaxel) is an analog of Docetaxel (HY-B0011), with anticancer activity. Docetaxel is a microtubule disassembly inhibitor, with antimitotic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 10-Acetyl docetaxel; PNU-101383. CAS No. 125354-16-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0018. | |
| Docetaxel | Docetaxel (RP-56976) is a microtubule depolymerization inhibitor, with an IC 50 of 0.2 μM. Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel arrests the cell cycle at G2/M and leads to cell apoptosis. Docetaxel has anti-cancer activity [1] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: RP-56976. CAS No. 114977-28-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0011. | |
| Docetaxel Trihydrate | Docetaxel Trihydrate (RP-56976 Trihydrate) is an antineoplastic agent and inhibits microtubule depolymerization with an IC 50 value of 0.2 μM [1]. Docetaxel Trihydrate is a semisynthetic analog of taxol and attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel Trihydrate arrests the cell cycle at G2/M and leads to cell apoptosis [1] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP-56976 Trihydrate. CAS No. 148408-66-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0011A. | |
| Docosahexaenoic acid | Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk. Uses: Scientific research. Group: Natural products. Alternative Names: DHA; Cervonic acid. CAS No. 6217-54-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B2167. | |
| Docosahexaenoic acid-d5 | Docosahexaenoic acid-d 5 is the deuterium labeled Docosahexaenoic Acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: DHA-d5; Cervonic acid-d5. CAS No. 1197205-71-2. Pack Sizes: 1 mg (1.50 mM * 2 mL in Ethanol). Product ID: HY-B2167S. | |
| Docosahexaenoic acid ethyl ester | Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ethyl docosahexaenoate. CAS No. 81926-94-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-107343. | |
| Docosahexaenoic acid methyl ester | Docosahexaenoic Acid methyl ester is a methylated docosahexaenoic acid analog which can be intercalated into membrane phospholipids without being oxidized or hydrolyzed. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Methyl docosahexaenoate; all cis-DHA methyl ester. CAS No. 2566-90-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-101541. | |
| Docosahexaenoyl glycerol | Docosahexaenoyl glycerol is an analog of endocannabinoid, which stimulates the glucose uptake and exhibits anti-inflammatory efficacy [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 140670-40-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148940. | |
| Docosahexaenoyl serotonin | Docosahexaenoyl serotonin (DHA-5-HT) is an endogenous n-3 fatty acid-serotonin conjugate. Docosahexaenoyl serotonin is an inhibitor of IL-17. Docosahexaenoyl serotonin has anti-inflammatory activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DHA-5-HT. CAS No. 283601-58-1. Pack Sizes: 5 mg (20.55 mM * 500 μL in Ethanol); 10 mg (20.55 mM * 1 mL in Ethanol). Product ID: HY-131397. | |
| Docosane | Docosane, a straight chain alkane, can be used to synthesize structural composites with thermal energy storage/release capability [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 629-97-0. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-N9929. | |
| Docosanedioic acid | Docosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Docosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Natural products. CAS No. 505-56-6. Pack Sizes: 250 mg; 1 g; 5 g; 10 g. Product ID: HY-W034918. | |
| Docosanoic acid | Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a K d of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Behenic acid. CAS No. 112-85-6. Pack Sizes: 100 mg. Product ID: HY-W013049. | |
| Docosapentaenoic acid (22n-3) | Docosapentaenoic acid (22n-3) is a component of phospholipids found in all animal cell membranes. Uses: Scientific research. Group: Natural products. CAS No. 24880-45-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-113159. | |
| Docosatrienoic Acid | Docosatrienoic acid is a rare ω-3 fatty acid; inhibits LTB4 binding to pig neutrophil membranes with an K i of 5 μM. Uses: Scientific research. Group: Natural products. Alternative Names: cis-13,16,19-docosatrienoic acid; (13Z,16Z,19Z)-13,16,19-Docosatrienoic acid. CAS No. 28845-86-5. Pack Sizes: 5 mg (149 mM * 100 μL in Ethanol); 10 mg (149 mM * 200 μL in Ethanol). Product ID: HY-101408. | |
| Docusate Sodium | Docusate Sodium (Dioctyl sulfosuccinate sodium salt) is one of the main components in stool softeners. Docusate Sodium is a sulfated surfactant and may inactivate viral pathogens by disrupting viral envelopes and/or denaturing/disassociating proteins. Docusate Sodium is effective in vitro against wild type and drug-resistant strains of HSV type 1 and 2. Docusate Sodium is an obesogen. Docusate Sodium with developmental exposure leads to increased adult adiposity, inflammation, metabolic disorder and dyslipidemia in offspring fed a standard diet in mice [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dioctyl sulfosuccinate sodium salt. CAS No. 577-11-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1268. | |
| Dodecamethylpentasiloxane | Dodecamethylpentasiloxane is a component of siloxanes and can be used as silicone oil. Dodecamethylpentasiloxane exhibits insecticidal activity against bed bug [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 141-63-9. Pack Sizes: 10 mL; 10 mM * 1 mL. Product ID: HY-W011035. | |
| Dodecane | Dodecane (Ba 51-090453) is an ester product. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ba 51-090453. CAS No. 112-40-3. Pack Sizes: 10 mM * 1 mL; 100 g. Product ID: HY-W099602. | |
| Dodecane-1,12-diol | Dodecane-1,12-diol (Dodecamethylene glycol) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Dodecamethylene glycol. CAS No. 5675-51-4. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-W014779. | |
| Dodecane-d26 | Dodecane-d 26 is the deuterium labeled Dodecane[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 16416-30-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-W099602S. | |
| Dodecanedioic acid | Dodecanedioic acid (C12) is a dicarboxylic acid with a metabolic pathway intermediate to those of lipids and carbohydrates. Uses: Scientific research. Group: Natural products. CAS No. 693-23-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W012241. | |
| Dodecylbenzenesulfonic acid | Dodecylbenzenesulfonic acid is a dopant for conductive polymers and a strong acid catalyst for amino-crosslinked coatings. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Dodecylbenzenesulphonic acid. CAS No. 27176-87-0. Pack Sizes: 500 g. Product ID: HY-W250144. | |
| Dodecyl gallate | Dodecyl gallate (Lauryl gallate) has been widely used as an antioxidant in food manufacturing, as well as in the pharmaceutical and cosmetic industries. Dodecyl gallate also acts antibacterial activity specifically against Gram-positive bacteria. Dodecyl gallate also is active against a highly relevant animal virus such as African swine fever virus (ASFV) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lauryl gallate. CAS No. 1166-52-5. Pack Sizes: 10 mM * 1 mL; 25 g; 50 g. Product ID: HY-124082. | |
| Dodecylphosphocholine | Dodecylphosphocholine is a detergent widely utilized in NMR studies of membrane proteins [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 29557-51-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-116013. | |
| Dodecylphosphocholine-d38 | Dodecylphosphocholine-d 38 8 is the deuterium labeled Dodecylphosphocholine. Dodecylphosphocholine is a detergent widely utilized in NMR studies of membrane proteins[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 130890-78-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-116013S. | |
| Dodecyltrimethylammonium bromide | Dodecyltrimethylammonium bromide (DTAB) is a surfactant. Dodecyltrimethylammonium bromide interacts with DNA and changes the mechanical properties of DNA on binding and the specific binding parameters of the interaction [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1119-94-4. Pack Sizes: 5 g. Product ID: HY-D0838. | |
| DODMA | DODMA is a cationic lipid that can be used to prepare lipid nanoparticles. DODMA can be used for drug delivery [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 104162-47-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-112755. | |
| Dofetilide | Dofetilide (UK 68789), as a class III antiarrhythmic agent, is an orally active, potent and specific IKr blocker. Dofetilide can be used for the research of cardiovascular disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK 68789. CAS No. 115256-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0232. | |
| DOI hydrochloride | DOI hydrochloride is a serotonin 5-HT 2A / 2C receptor agonist with K i values of 0.7 nM, 2.4 nM and 20 nM for h5-HT 2A , h5-HT 2C and h5-HT 2B receptors, respectively. DOI hydrochloride can across the blood-brain barrier. DOI hydrochloride increases head twitches in mice [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 42203-78-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103124. | |
| Dolasetron | Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDL-73147. CAS No. 115956-12-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0750. | |
| Dolasetron Mesylate hydrate | Dolasetron Mesylate hydrate (MDL-73147EF hydrate) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDL-73147EF hydrate. CAS No. 878143-33-0. Pack Sizes: 100 mg; 200 mg. Product ID: HY-B0750B. | |
| Dolastatin 10 | Dolastatin 10 (DLS 10) is a potent antimitotic peptide that inhibits tubulin polymerization. Uses: Scientific research. Group: Peptides. Alternative Names: DLS 10; NSC 376128. CAS No. 110417-88-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15580. | |
| Dolutegravir | Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC 50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC 50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC 50 =3.6-5.8 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S/GSK1349572. CAS No. 1051375-16-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-13238. | |
| Dolutegravir sodium | Dolutegravir sodium (S/GSK1349572 sodium) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC 50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir sodium (S/GSK1349572 sodium) inhibits HIV-1 viral replication with an IC 50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir sodium (S/GSK1349572 sodium) retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC 50 =3.6-5.8 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S/GSK1349572 sodium. CAS No. 1051375-19-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13238A. | |
| Domagrozumab | Domagrozumab is an anti- myostatin humanized monoclonal antibody with a K D value of 2.6 pM for human myostatin. Domagrozumab induces muscle anabolic activity. Domagrozumab can be used in research of duchenne muscular dystrophy (DMD) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF-06252616. CAS No. 1629605-31-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99857. | |
| Domatinostat | Domatinostat (4SC-202 free base) is a selective class I HDAC inhibitor with IC 50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4SC-202 free base. CAS No. 910462-43-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16012A. | |
| Domatinostat tosylate | Domatinostat tosylate (4SC-202) is a selective class I HDAC inhibitor with IC 50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4SC-202. CAS No. 1186222-89-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16012. | |
| Domiphen bromide | Domiphen bromide is a chemical antiseptic and a quaternary ammonium compound, used as a cationic surfactant. Uses: Scientific research. Group: Signaling pathways. CAS No. 538-71-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-B1467. | |
| Domperidone | Domperidone (R33812) is an orally active and selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R33812. CAS No. 57808-66-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0411. | |
| Domperidone monomaleate | Domperidone (R33812) monomaleate is an orally active and selective dopamine-2 receptor antagonist. Domperidone monomaleate acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R33812 monomaleate. CAS No. 83898-65-1. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0411A. | |
| Domvanalimab | Domvanalimab (AB154) is an anti- TIGIT humanized monoclonal antibody. Domvanalimab binds human TIGIT9 and blocks the TIGIT-CD155 interaction. Domvanalimab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AB154. CAS No. 2368219-35-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99858. | |
| Donanemab | Donanemab (LY3002813) is a humanized IgG1 monoclonal antibody directed at an N-terminal pyroglutamate amyloid beta (Aβ) epitope. Donanemab has the potential for early Alzheimer's disease research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY3002813. CAS No. 1931944-80-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99859. | |
| Donepezil | Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC 50 s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E2020 free base. CAS No. 120014-06-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14566. | |
| Donepezil-d5 | Donepezil-d 5 is deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: E2020-d5 free base. CAS No. 1128086-25-8. Pack Sizes: 1 mg. Product ID: HY-14566S1. | |
| Donepezil-d5 hydrochloride | Donepezil-d 5 (hydrochloride) is deuterium labeled Donepezil (Hydrochloride). Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity. Donepezil shows high selectivity for AChE over BuChE[1]. Donepezil exhibits neuroprotective effect on Aβ42 neurotoxicity[2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: E2020-d5. CAS No. 1883548-90-0. Pack Sizes: 1 mg. Product ID: HY-B0034S. | |
| Donepezil Hydrochloride | Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC 50 of 6.7 nM for AChE activity. Donepezil shows high selectivity for AChE over BuChE [1]. Donepezil exhibits neuroprotective effect on Aβ42 neurotoxicity [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E2020. CAS No. 120011-70-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-B0034. | |
| Dopal | Dopal is an aldehyde that can be generated in Parkinson's disease by enzymatic degradation of dopamine. Dopal can generate reactive oxygen species (ROS) , and triggers aggregation of α-synuclein. Dopal elicits α-synuclein accumulation and hampers α-synuclein clearance in primary neurons [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 5707-55-1. Pack Sizes: 5 mg (65.72 mM * 500 μL in Methanol); 10 mg (65.72 mM * 1 mL in Methanol). Product ID: HY-121252. | |
| Dopamine | Dopamine is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine plays several important roles in the brain and body [1]. Dopamine acts through D2 dopamine receptor s to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis [1]. Uses: Scientific research. Group: Natural products. Alternative Names: ASL279 free base. CAS No. 51-61-6. Pack Sizes: 10 mM * 1 mL; 10 mg. Product ID: HY-B0451. | |
| Dopamine D2 receptor antagonist-1 | Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R) with sub-mM affinity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1055411-77-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129946. | |
| Dopamine-d3 hydrochloride | Dopamine-d 3 (hydrochloride) is the deuterium labeled Dopamine hydrochloride (ASL279)-[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: ASL279-d3. CAS No. 53587-30-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0451AS4. | |
| Dopamine-d5 hydrochloride | Dopamine-d 5 (hydrochloride) is the deuterium labeled Dopamine (hydrochloride). Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body[1]. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 2193106-55-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0451AS7. | |
| Dopamine hydrochloride | Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body [1]. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptor s to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis [1]. Uses: Scientific research. Group: Natural products. Alternative Names: ASL279. CAS No. 62-31-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0451A. | |
| DOPE | DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine. CAS No. 4004-5-1. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-112005. | |
| Dopexamine hydrochloride | Dopexamine hydrochloride is a β2 adrenergic receptor agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FPL60278AR. CAS No. 86484-91-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00205. | |
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