MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Duloxetine hydrochloride | Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a K i of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-Duloxetine hydrochloride; LY-248686 hydrochloride. CAS No. 136434-34-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0161A. |  |
| Duocarmycin Analog | Duocarmycin Analog is an analog of Duocarmycin, and used as an DNA alkylator and ADC cytotoxin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 372954-15-9. Pack Sizes: 1 mg. Product ID: HY-129355. | |
| DUPA | DUPA, belongs to a class of glutamate ureas, is used as the targeting moiety in agent conjugate to selectively deliver cytotoxic agents to prostate cancer cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 302941-52-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111606. | |
| Dupilumab | Dupilumab (REGN-668) is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN-668; SAR-231893. CAS No. 1190264-60-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9926. | |
| Duramycin | Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Moli1901; Lancovutide. CAS No. 1391-36-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-106302. | |
| Durlobactam sodium | Durlobactam sodium salt (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC 50 s of 4, 14 and 190 nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ETX2514. CAS No. 1467157-21-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117974. | |
| Durvalumab | Durvalumab (MEDI 4736) is an human anti- PD-L1 monoclonal antibody [1]. Durvalumab (MEDI4736) completely blocks the binding of PD-L1 to both PD-1 and CD80 , with IC 50 s of 0.1 and 0.04 nM, respectively [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI 4736. CAS No. 1428935-60-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9919. | |
| Durvalumab (anti-PD-L1) | Durvalumab (anti-PD-L1)(MEDI 4736) is a human anti- PD-L1 protein monoclonal antibody. Durvalumab (anti-PD-L1) completely blocks PD-L1 binding to PD-1 and CD80 , IC 50 are 0.1 and 0.04 nM respectively, has anti-tumor activity [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI 4736 (anti-PD-L1). CAS No. 1428935-60-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9919A. | |
| Dusquetide | Dusquetide (SGX942) is a first-in-class innate defense regulator (IDR). Dusquetide modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide shows activity in both reducing inflammation and increasing clearance of bacterial infection [1]. DAMPs: damage-associated molecular patterns; PAMPs: pathogen-associated molecular patterns. Uses: Scientific research. Group: Peptides. Alternative Names: SGX942. CAS No. 931395-42-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2076. | |
| Dutasteride | Dutasteride (GG745) is a potent inhibitor of both 5α-reductase isozymes. Dutasteride may possess off-target effects on the androgen receptor (AR) due to its structural similarity to DHT [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GG 745; GI 198745. CAS No. 164656-23-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13613. | |
| Dutogliptin | Dutogliptin (PHX-1149 free base) is an orally available, potent, and selective dipeptidyl peptidase-4 ( DPP4 ) inhibitor for the treatment of type 2 diabetes mellitus. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PHX-1149 free base. CAS No. 852329-66-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-10286. | |
| Duvakitug | Duvakitug is a humanized IgG1-λ2 monoclonal antibody targeting to TNFSF15 /TL1A. Duvakitug' main expression system is CHOK1SV cells endogenously expressing glutamine synthetase (GS). Duvakitug can be used in the study of Crohn's Disease (CD) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2750005-84-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990006. | |
| Duvelisib | Duvelisib (IPI-145) is a selectivite p100δ inhibitor with IC 50 of 2.5 nM, 27.4 nM, 85 nM and 1602 nM for p110δ, P110γ, p110β and p110α, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IPI-145; INK1197. CAS No. 1201438-56-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17044. | |
| Duvortuxizumab | Duvortuxizumab (MGD 011) is a chimeric humanized IG antibody targeting CD19 and CD3E [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MGD 011. CAS No. 1831098-91-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99868. | |
| D-Valine | D-Valine is the enantiomer of L-Valine (HY-N0717). L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid. Uses: Scientific research. Group: Natural products. CAS No. 640-68-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g; 25 g. Product ID: HY-N0717A. | |
| D-Valinol | (2R)-2-Amino-3-methylbutan-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Peptides. Alternative Names: (R)-2-Amino-3-methyl-butanol. CAS No. 4276-9-9. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-30167. | |
| D-Val-Leu-Arg-pNA acetate | D-Val-Leu-Arg-pNA (acetate) is the acetate form of D-Pro-Phe-Arg-p-nitroanilide (pNa). D-Pro-Phe-Arg-p-nitroanilide (pNa) is the substrate for kallikrein and can be used to assay the activity of kallikrein [1]. Uses: Scientific research. Group: Peptides. CAS No. 162303-66-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-114150D. | |
| D-Val-Leu-Lys-pNA dihydrochloride | D-Val-Leu-Lys-pNA dihydrochloride (D-VLK-pNA dihydrochloride) is a colorimetric substrate for plasminolytic activity. D-Val-Leu-Lys-pNA dihydrochloride is catalytically bound and hydrolyzed by plasmin to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of plasminolytic activity [1]. Uses: Scientific research. Group: Peptides. Alternative Names: D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride. CAS No. 62354-43-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-131409. | |
| DX600 | DX600 is a selective ACE2 specific inhibitor ( K D : 1.3 nM), and does not cross-react with ACE. DX600 exacerbates diabetes-induced cardiovascular dysfunction and the increase in cardiac and renal NOX activity [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 478188-26-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2222. | |
| Dxd | Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC 50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Exatecan derivative for ADC. CAS No. 1599440-33-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13631D. | |
| D-Xylulose | D-xylulose is a precursor of the pentiol D-arabitol. Uses: Scientific research. Group: Natural products. CAS No. 551-84-8. Pack Sizes: 5 mg (0.5 M * 66.6 μL in Water); 10 mg (0.5 M * 133.2 μL in Water). Product ID: HY-W010256. | |
| Dyclonine hydrochloride | Dyclonine (Dyclocaine) hydrochloride is an orally effective ALDH covalent inhibitor (crosses blood-brain barrier), with an IC 50 of 35 μM for ALDH2 and 76 μM for ALDH3A1. Dyclonine hydrochloride has sensitizing activities for targeted cancer cells and antibacterial. Dyclonine hydrochloride is also a local agent that can suppress or relieve pain. that blocks the transmission of various nerve impulses or stimuli and inhibits the sensation of touch and pain [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dyclocaine hydrochloride. CAS No. 536-43-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B0364A. | |
| Dydrogesterone | Dydrogesterone is a potent, orally active progestogen indicated in a wide variety of gynaecological conditions related to progesterone deficiency. Uses: Scientific research. Group: Signaling pathways. CAS No. 152-62-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0257A. | |
| Dymanthine | Dymanthine is an anthelminthic. Dymanthine has the potential for the research of multiple intestinal helmintic infestations [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N,N-Dimethyloctadecan-1-amine. CAS No. 124-28-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-121429. | |
| Dynorphin A | Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS). Dynorphin A is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR). Dynorphin A can induce neuronal death, and can be used in the research of neurological disease [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 80448-90-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1333. | |
| Dynorphin A (1-8) | Dynorphin A (1-8) is the predominant opioid peptide identified in placental tissue extracts. Dynorphin A (1-8) is the most likely natural ligand of the kappa receptor. The binding of 3H-Bremazocine to the purified kappa receptor is inhibited by Dynorphin A (1-8) (IC 50 =303 nM) [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 75790-53-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P2159. | |
| Dyrk1A-IN-4 | Dyrk1A-IN-4 (compound 48) is a potent and orally active DYRK1A and DYRK2 inhibitor with IC 50 s of 2 nM and 6 nM, respectively. Dyrk1A-IN-4 has anticancer effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2091883-59-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-147066. | |
| DZD1516 | DZD1516 is a potent and selective HER2 inhibitor ( IC 50 =0.56 nM) with good blood-brain permeability. DZD1516 exhibits antitumor activity in CNS and subcutaneous xenograft mouse models [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2387570-00-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155079. | |
| E1231 | E1231 is an orally active activator of Sirtuin 1 ( SIRT1 ) ( EC 50 =0.83 μM), to modulate cholesterol and lipid metabolism. E1231 interactes with SIRT1 (K D =9.61 μM) and deacetylated liver X receptor-alpha ( LXRα ), and increases ATP-binding cassette transporter A1 (ABCA1) expression. E1231 also reduces atherosclerotic plaque development in ApoE -/- mice model. E1231 can be used for research in cholesterol and lipid disorder-related diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-{4-[2-(5-Methylfuran-2-yl)quinoline-4-carbonyl]piperazin-1-yl}ethan-1-one. CAS No. 1031195-19-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117006. | |
| E1R | E1R is a positive allosteric modulator of sigma-1 receptors ( Sig1R PAM ) with cognition-enhancing activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1301211-78-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116463. | |
| E 2012 | E 2012 is a potent gamma (γ) secretase modulator without affecting Notch processing. E 2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer's disease by reduction of amyloid β-42, and induces cataract following repeated doses in the rat [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 870843-42-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 100 mg. Product ID: HY-10016. | |
| E235 | E235 is an expression regulator of activates transcription factor 4 ( ATF4 ). E235 reduces cell viability by activating integrated stress response (ISR) and DNA damage response signals. E235 has anti-proliferative activity and can be used for tumor research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 891894-69-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153339. | |
| E260 | E260 is a Fer / FerT kinase inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1241537-79-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112097. | |
| (E)-2-Methyl-2-pentenoic acid | (E)-2-Methyl-2-pentenoic acid is the component can be used to synthesize the cytotoxic natural product Lactimidomycin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 16957-70-3. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-W010533. | |
| (E)-3,4,5-Trimethoxycinnamic acid | (E)-3,4,5-Trimethoxycinnamic acid (TMCA) is a cinnamic acid substituted by multi-methoxy groups. (E)-3,4,5-Trimethoxycinnamic acid is an orally active and potent GABA A /BZ receptor agonist. (E)-3,4,5-Trimethoxycinnamic exhibits favourable binding affinity to 5-HT 2C and 5-HT 1A receptor, with IC 50 values of 2.5 and 7.6 μM, respectively. (E)-3,4,5-Trimethoxycinnamic acid shows anticonvulsant and sedative activity. (E)-3,4,5-Trimethoxycinnamic acid can be used for the research of insomnia, headache and epilepsy [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TMCA. CAS No. 20329-98-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W050162. | |
| (E)-3,4-Dimethoxycinnamic acid | (E)-3,4-Dimethoxycinnamic acid is the less active isomer of 3,4-Dimethoxycinnamic acid. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway [1]. Anti-apoptotic effects [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (E)-O-Methylferulic acid. CAS No. 14737-89-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N1778A. | |
| E-3620 | E-3620 is a potent 5-HT 3 receptor antagonist. E-3620 can be used for the research of dyskinesi and gastrointestinal motility [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 151213-86-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19199. | |
| (E)-3',6-Disinapoylsucrose | (E)-3',6-Disinapoylsucrose, the index component of Yuanzhi ( Polygala tenuifolia Willd), possesses potent antioxidant activity and antidepressant effect [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 139891-98-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N1414. | |
| E3 ligase Ligand 32 | E3 ligase Ligand 32 (First product in Example 52) is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 32 can be connected to the ligand for protein by a linker to form PROTACs and can be used for the synthesis of PROTAC SMARCA2/4-degrader-29 (HY-162743) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2300099-98-1. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W382038. | |
| E-4031 | E-4031 is a selective hERG potassium channel blocker for use in class III anti-arrhythmic studies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 113559-13-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15551. | |
| (E)-4-Hydroxytamoxifen | (E)-4-Hydroxytamoxifen ((E)-Afimoxifene), the less active isomer of (Z)-4-hydroxytamoxifen, is an estrogen receptor modulator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E)-Afimoxifene. CAS No. 174592-47-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-16950B. | |
| (E)-4-Oxo-2-nonenal | (E)-4-Oxo-2-nonenal (4-ONE) is one of the major hemolytic decomposition products of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a major product of the FeII-mediated breakdown of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a potent transient receptor potential ankyrin 1 (TRPA1) agonist [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-ONE. CAS No. 103560-62-9. Pack Sizes: 5 mg; 500 μg. Product ID: HY-114524. | |
| (E)-5-O-Cinnamoylquinic acid | (E)-5-O-Cinnamoylquinic acid is the isomer of 5-O-Cinnamoylquinic acid. 5-O-Cinnamoylquinic acid is a co-pigment. 5-O-Cinnamoylquinic acid could form the stable blue solution to clarify the mechanism of blue sepal-color development of hydrangea [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 6470-68-4. Pack Sizes: 5 mg. Product ID: HY-N8224A. | |
| E-64 | E-64 (Proteinase inhibitor E 64) is a potent irreversible inhibitor against general cysteine proteases with IC 50 of 9 nM for papain. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Proteinase inhibitor E 64. CAS No. 66701-25-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15282. | |
| E7016 | E7016 (GPI 21016) is an orally available PARP inhibitor. E7016 can enhance tumor cell radiosensitivity in vitro and in vivo through the inhibition of DNA repair. E7016 acts as a potential anticancer agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GPI 21016. CAS No. 902128-92-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13540. | |
| E7090 | E7090 is an orally available, potent, and selective FGFR inhibitor with IC 50 s of 0.71 nM, 0.50 nM, 1.2 nM, and 120 nM for FGFR1/FGFR2/FGFR3/FGFR4 , respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1622204-21-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101466. | |
| E7090 succinate | E7090 succinate is an orally available, selective and potent inhibitor of FGFR1, FGFR2 and FGFR3 tyrosine kinase activities, with IC 50 values of 0.71 nM, 0.50 nM, 1.2 nM, and 120 nM for FGFR1/2/3/4, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1879965-80-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101466A. | |
| E-7386 | E-7386 is an orally active CBP/beta-catenin modulator. Uses: Scientific research. Group: Signaling pathways. CAS No. 1799824-08-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111386. | |
| E7820 | E7820 (ER68203-00), an orally active aromatic sulfonamide derivative, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium. E7820 inhibits rat aorta angiogenesis with an IC 50 of 0.11 μg/ml. E7820 modulates α-1, α-2, α-3, and α-5 integrin mRNA expression. Antiangiogenic and antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ER68203-00. CAS No. 289483-69-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14571. | |
| EA2 | EA2 is a biological active peptide. (This is a peptide substrate for polypeptide N-acetylgalactosaminyltransferase (polypeptide GalNAc-T).). Uses: Scientific research. Group: Peptides. CAS No. 562082-63-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5473. | |
| EA4 | EA4, a derivative of quinone, is an inhibitor for both rPLA and cPLA. EA4 can inhibit rPLA 2 with a K i value of 130 μM. EA4 can be used for the research of hemostasis, thrombosis, and erythropoiesis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 389614-94-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131722. | |
| EACC | EACC is a reversible autophagy inhibitor, which can block autophagic flux. EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 864941-31-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-129111. | |
| Eact | Eact is a selective and potent activator of TMEM16A , directly activates the TRPV1 channels in sensory nociceptors and produces itch, acute nociception and thermal hypersensitivity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 461000-66-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103368. | |
| (E)-AG 556 | (E)-AG 556 is a highly selective EGFR inhibitor and also blocks LPS-induced TNF-α production [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E)-Tyrphostin AG 556. CAS No. 133550-41-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101041. | |
| EB1 | EB1 is the inhibitor of kinases MNK with IC 50 s of 0.69 μM (MNK1) and 9.4 μM (MNK2). EB1 selectively inhibits the growth of cancer cells, but not normal cells. EB1 also increases cell apoptosis and suppresses eIF4E phosphorylation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 42951-68-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146805. | |
| Ebastine | Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LAS-W 090; RP64305. CAS No. 90729-43-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0674. | |
| Ebdarokimab | Ebdarokimab (AK101) is a humanized IgG1-κ antibody, usually expressed in CHO (Chinese Hamster Ovary) cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2393651-11-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99869. | |
| Ebeiedinone | Ebeiedinone, a steroidal alkaloid from Fritillaria species, inhibits the bioactivity of human whole blood cholinesterase ( ChE ) at the concentration of 0.1 mM, with the inhibitory effects of 69.0% [1]. Uses: Scientific research. Group: Natural products. CAS No. 25650-68-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107275. | |
| Eberconazole nitrate | Eberconazole nitrate is a dichlorinated imidazole derivative with antifungal activity. Eberconazole nitrate is more effective than Clotrimazole (HY-10882), Ketoconazole (HY-B0105), and Miconazole (HY-B0454). Eberconazole nitrate has potential for the study of dermatophytosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130104-32-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106542A. | |
| (E)-β-Farnesene | (E)-β-Farnesene (trans-β-Farnesene) is an aphid alarm pheromone, which can be found in Phlomis aurea Decne essential oil. (E)-β-Farnesene shows good binding score with a value of -30.64 kcal/mol to the CDK2 receptor. (E)-β-Farnesene also exhibits good affinity to odorant-binding protein 3 ( OBP3 ). (E)-β-Farnesene can be used as a feeding stimulant for the sand fly Lutzomyia longipalpis [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: trans-β-Farnesene. CAS No. 18794-84-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-N7364. | |
| (E)-β-Ionone | (E)-β-Ionone is the isomer of β-Ionone (HY-W015084). β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. β-Ionone has anti-cancer activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: β-Lonone. CAS No. 79-77-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W015084A. | |
| Eblasakimab | Eblasakimab (ASLAN004; CSL-334) is a human IgG4 antibody that specifically targets IL13RA1 and is primarily expressed by CHO-K1 cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ASLAN004; CSL-334; MK-6105. CAS No. 2445460-16-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99870. | |
| Ebrotidine | Ebrotidine(FI 3542) is a competitive H2-receptor antagonist (Ki= 127. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FI3542. CAS No. 100981-43-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15538. | |
| Ebselen | Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker [1] [2]. Ebselen potently inhibits M pro ( IC 50 =0.67 μM) and COVID-19 virus ( EC 50 =4.67 μM) [3].Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SPI-1005; PZ-51; CCG-39161. CAS No. 60940-34-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13750. | |
| EC19 | EC19 is an analogue of 13-cis retinoic acid (HY-15127). EC19 shows embryo toxicity. EC19 causes mild effects on upper beak outgrowth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1010694-08-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110296. | |
| EC23 | EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGN 190205; BASF-46928. CAS No. 104561-41-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12309. | |
| EC330 | EC330 is a leukemia inhibitory factor ( LIF ) inhibitor. EC330 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2016795-77-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100949. | |
| Ecabet sodium | Ecabet sodium (TA-2711) is currently applied to some gastrointestinal disease by inhibiting the ROS production and improving Helicobacter pylori eradication [1]. Ecabet sodium reduces apoptosis [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TA-2711. CAS No. 86408-72-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0691A. | |
| E-Cadherin activator-1 | E-cadherin activator-1 (Compound 13m) is an E-Cadherin activator. E-cadherin activator-1 can be used in the study of colorectal carcinoma [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 912787-60-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-164712. | |
| Ecamsule | Ecamsule is a broad-spectrum UVA filter that can be used in sunscreen product. Ecamsule reduces biological damage caused by solar radiation such as pyrimidine dimer formation, p53 protein accumula-tion, or collagenase 2 expression. Ecamsule has the potential for the research of polymorphous light eruption (PMLE) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 92761-26-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16182. | |
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