MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Embelin | Embelin (Embelic acid), a potent, nonpeptidic XIAP inhibitor ( IC 50 =4.1 μM), inhibits cell growth, induces apoptosis , and activates caspase-9 in prostate cancer cells with high levels of XIAP. Embelin blocks NF-kappaB signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Embelin also induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Embelic acid; Emberine; NSC 91874. CAS No. 550-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17473. |  |
| EMD386088 | EMD386088 is a potent serotonin 6 receptor (5-HT6R) agonist. EMD386088 induces cell death. EMD386088 regulates the activity of ERK1/2. EMD386088 has the potential for the research of alzheimer's disease (AD) and schizophrenia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1171123-46-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103130. | |
| Emedastine | Emedastine is an orally active, selective and high affinity histamine H 1 receptor antagonist with a K i value of 1.3 nM. Emedastine is a benzimidazole derivative with potent antiallergic properties and used for allergic rhinitis, allergic skin diseases and allergic conjunctivitis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 87233-61-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-108411. | |
| EMI1 | EMI1 is an EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S inhibitor. EMI1 can be used for the research of mutant EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 35773-42-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138072. | |
| EMI48 | EMI48, the derivative of EMI1, displays greater potency toward mutant EGFR than EMI1. EMI48 inhibits EGFR triple mutants [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 34564-13-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-131066. | |
| Emibetuzumab | Emibetuzumab (LY2875358) is a humanized bivalent MET antibody (IgG4 type). Emibetuzumab shows high neutralization and internalization activities, resulting in inhibition of both HGF -dependent and HGF -independent MET pathway activation and tumor growth. Emibetuzumab can be used in study of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY2875358. CAS No. 1365287-97-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99192. | |
| Emicerfont | Emicerfont is a corticotropin-releasing factor type 1 ( CRF 1 ) receptor antagonist with an IC 50 of 66 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW876008. CAS No. 786701-13-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14367. | |
| Emicizumab | Emicizumab is a bispecific monoclonal antibody that bridges activated factor IX and factor X to replace the function of missing activated factor VIII, thereby restoring hemostasis. Emicizumab can be used for hemophilia A research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1610943-06-0. Pack Sizes: 1 mg. Product ID: HY-P9940. | |
| Emidurdar | Endovion is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker. Endovion (NS3728) is also an Anoctamin-1 (ANO 1) channel inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Endovion; NS3728. CAS No. 265646-85-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105917. | |
| Emiglitate | Emiglitate (BAY o 1248) is a potent, selective and competitive inhibitor of α-glucoside hydrolase. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY o 1248. CAS No. 80879-63-6. Pack Sizes: 1 mg. Product ID: HY-16194. | |
| Emixustat | Emixustat is an orally active RPE65 inhibitor with an IC 50 value of 4.4 nM. Emixustat is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACU-4429. CAS No. 1141777-14-1. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19720. | |
| Emixustat hydrochloride | Emixustat (ACU-4429) hydrochloride is an orally active RPE65 inhibitor with an IC 50 value of 4.4 nM. Emixustat hydrochloride is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACU-4429 hydrochloride. CAS No. 1141934-97-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19720A. | |
| Emodepside | Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bay 44-4400. CAS No. 155030-63-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101476. | |
| Emodin | Emodin (Frangula emodin), an anthraquinone derivative, is an anti- SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction [1]. Emodin inhibits casein kinase-2 ( CK2 ). Anti-inflammatory and anticancer effects [2]. Emodin is a potent selective 11β-HSD1 inhibitor with the IC 50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Frangula emodin. CAS No. 518-82-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-14393. | |
| Emodin-8-glucoside | Emodin-8-glucoside is an anthraquinone derivative isolated from Aloe vera, binds to minor groove of DNA [1]. Uses: Scientific research. Group: Natural products. CAS No. 23313-21-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0311. | |
| Emoxypine succinate | Emoxypine succinate is an antioxidant. Emoxypine succinate can be used for the research of post-traumatic [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Ethyl-3-hydroxy-6-methylpyridine succinate. CAS No. 127464-43-1. Pack Sizes: 500 mg; 1 g. Product ID: HY-W002620A. | |
| EMPA | EMPA is a high-affinity, reversible and selective orexin OX 2 receptor antagonist. [ 3 H]EMPA binds to human and rat OX 2 -HEK293 membranes with K D values of 1.1 and 1.4 nM respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 680590-49-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108682. | |
| Empagliflozin | Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 ( SGLT-2 ) inhibitor with an IC 50 of 3.1 nM for human SGLT-2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 10773. CAS No. 864070-44-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-15409. | |
| Empagliflozin-d4 | Empagliflozin-d 4 is deuterium labeled Empagliflozin. Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: BI 10773-d4. CAS No. 2749293-95-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-15409S. | |
| Empasiprubart | Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2 , preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation. Empasiprubar can prevent complement mediated autoimmune hemolytic anemia and antibody mediated organ transplant rejection. Empasiprubar can prevent neuroglial lymphoconjunctival injury in GM1 antibody mediated mouse models [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ARGX-117. CAS No. 2579031-19-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990025. | |
| Empesertib | Empesertib (BAY 1161909) is a potent Mps1 inhibitor, with an IC 50 of < 1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1161909. CAS No. 1443763-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12858. | |
| Emraclidine | Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator (WO2018002760, compound 11). Emraclidine can be used for the research of neurological diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CVL-231. CAS No. 2170722-84-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132812. | |
| Emricasan | Emricasan (PF 03491390) is an orally active and irreversible pan-caspase inhibitor. Emricasan inhibits Zika virus (ZIKV) -induced increases in caspase-3 activity and protected human cortical neural progenitors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF 03491390; IDN-6556. CAS No. 254750-02-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10396. | |
| Emrusolmin | Emrusolmin (Anle138b), an oligomeric aggregation inhibitor, blocks the formation of pathological aggregates of prion protein (PrPSc) and of α-synuclein (α-syn). Emrusolmin strongly inhibits oligomer accumulation, neuronal degeneration, and disease progression in vivo. Emrusolmin has low toxicity and an excellent oral bioavailability and blood-brain-barrier penetration. Emrusolmin blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Anle138b. CAS No. 882697-00-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101855. | |
| Emtricitabine | Emtricitabine is a nucleoside reverse transcriptase inhibitor ( NRTI ) with an EC 50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection. Uses: Scientific research. Group: Natural products. Alternative Names: BW1592. CAS No. 143491-57-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-17427. | |
| Emtricitabine (Standard) | Emtricitabine (Standard) is the analytical standard of Emtricitabine. This product is intended for research and analytical applications. Emtricitabine is a nucleoside reverse transcriptase inhibitor ( NRTI ) with an EC 50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection. Uses: Scientific research. Group: Natural products. Alternative Names: BW1592 (Standard). CAS No. 143491-57-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17427R. | |
| Emzeltrectinib | Emzeltrectinib is a potent tyrosine kinase inhibitor with antineoplastic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2223678-97-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-152840. | |
| EN4 | EN4 is a covalent ligand that targets cysteine 171 (C171) of MYC. EN4 is selective for c-MYC over N-MYC and L-MYC. EN4 inhibits MYC transcriptional activity, downregulates MYC targets, and impairs tumorigenesis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1197824-15-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134761. | |
| EN40 | EN40 is a potent, selective aldehyde dehydrogenase 3A1 (ALDH3A1) inhibitor as a covalent ligand, exhibits an IC 50 value of 2 uM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2094547-67-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122577. | |
| Enalaprilat-d5 | Enalaprilat-d 5 is the deuterium labeled Enalaprilat(MK-422), which is an angiotensin-converting enzyme (ACE) inhibitor. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: MK-422 d5. CAS No. 349554-00-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0231AS. | |
| Enalaprilat-d5 sodium | Enalaprilat-d 5 (sodium) is the deuterium labeled Enalaprilat(MK-422), which is an angiotensin-converting enzyme (ACE) inhibitor. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: MK-422-d5 sodium. CAS No. 1356922-29-6. Pack Sizes: 1 mg. Product ID: HY-B0231BS. | |
| Enalapril maleate | Enalapril (MK-421) maleate, the active metabolite of enalapril, is an angiotensin-converting enzyme (ACE) inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-421 maleate. CAS No. 76095-16-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0331A. | |
| Enapotamab | Enapotamab is an anti-AXL/UFO reference antibody. Enapotamab can be used to synthesis Bcl-xl inhibitor antibody-drug conjugates [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-AXL/UFO Reference Antibody (enapotamab). CAS No. 1912423-61-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99360. | |
| Enarodustat | Enarodustat is a potent and orally active hypoxia-inducible factor prolyl hydroxylase inhibitor, with an EC 50 of 0.22 μM. Enarodustat has the potential for renal anemia treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JTZ-951; SAL0951. CAS No. 1262132-81-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109057. | |
| Enasidenib | Enasidenib is an oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes, with IC 50 s of 100 and 400 nM against IDH2 R140Q and IDH2 R172K , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-221. CAS No. 1446502-11-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18690. | |
| Enasidenib mesylate | Enasidenib mesylate is a first-in-class, oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-221 mesylate. CAS No. 1650550-25-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18690A. | |
| Enavatuzumab | Enavatuzumab (PDL192; ABT-361) is a humanized IgG1 monoclonal antibody targeting the receptor of TNF-like weak inducer of apoptosis (TWEAK). TWEAK (Fn14; TNFRSF12A), the natural ligand of the TWEAK receptor (TweakR), stimulates multiple cellular responses. Enavatuzumab induces tumor growth inhibition through direct TweakR signaling and antibody dependent cell-mediated cytotoxicity (ADCC). Enavatuzumab can actively recruits and activates myeloid effectors to kill tumor cells. Enavatuzumab inhibits the growth of various human TweakR-positive cancer cell lines and xenografts in vitro and in vivo [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PDL192; ABT-361; Anti-TNFRSF12A/TWEAKR/CD266 Reference Antibody (enavatuzumab). CAS No. 1062149-33-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99361. | |
| Enavogliflozin | Enavogliflozin (DWP-16001), an antidiabetic agent, is an orally active, best-in-class and selective sodium-glucose cotransporter-2 ( SGLT-2 ) inhibitor [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DWP-16001. CAS No. 1415472-28-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-109144. | |
| Encainide | Encainide (MJ9067) is an antiarrhythmic agent with class IC activity. Encainide blocks voltage-dependent potassium channels. Encainide has the potential for life-threatening ventricular arrhythmias, symptomatic ventricular arrhythmias and supraventricular arrhythmias research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MJ9067. CAS No. 66778-36-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130335. | |
| Encaleret | Encaleret (CLTX-305) is an orally active CaSR antagonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CLTX-305. CAS No. 787583-71-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14401. | |
| Encenicline hydrochloride | Encenicline hydrochloride (EVP-6124 hydrochloride) is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors ( nAChRs ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: EVP-6124 hydrochloride. CAS No. 550999-74-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15430A. | |
| Encequidar | Encequidar (HM30181; HM30181A) is a potent and selective inhibitor of P-glycoprotein. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HM30181; HM30181A. CAS No. 849675-66-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13646. | |
| Encequidar mesylate | Encequidar mesylate (HM30181 mesylate; HM30181A mesylate) is a competitive and potent P-glycoprotein inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HM30181 mesylate; HM30181A mesylate. CAS No. 849675-87-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13646A. | |
| Enclomiphene citrate | Enclomiphene ((E)-Clomiphene) citrate is a potent and orally active non-steroidal estrogen receptor antagonist, with antioestrogenic property. Enclomiphene citrate can be used for the research of ovarian dysfunction, testosterone deficiency, male hypogonadism and type 2 diabetes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E)-Clomiphene citrate; trans-Clomiphene citrate; Enclomifene citrate. CAS No. 7599-79-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-118861A. | |
| Encorafenib | Encorafenib (LGX818) is a highly potent BRAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing BRAF V600E ( EC 50 =4 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: LGX818. CAS No. 1269440-17-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15605. | |
| Endo-1,3-β-glucanase | Endo-1,3-β-glucanase specifically hydrolyzes β-1,3-glycosidic bonds randomly along the β-glucan chain, and the final product is mainly glucan oligosaccharide. Endo-1,3-β-glucanase is produced by a variety of fungi, is often used in biochemical studies [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lyticase. CAS No. 9025-37-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-P3004. | |
| Endo-1,4-β-mannanase | Endo-1,4-β-mannanase is an important catalytic agent that randomly cleave the β-1,4-linkage in the mannan backbone and release short β-1,4-mannooligosaccharides and mannose [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 37288-54-3. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-E70110. | |
| Endo-1,4-β-xylanase | Endo-1,4-β-xylanase (Xylanase) is an arabinoxylan (AX) degrading enzyme and a glycoside hydrolase, is often used in biochemical studies. Endo-1,4-β-xylanase cleaves the β-xylosidic bond between two d-xylopyranosyl residues linked in β-(1,4) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CtXyn11A; EC 3.2.1.8. CAS No. 9025-57-4. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-P3017. | |
| Endo-β-Galactosidase | Endo-β-Galactosidase catalyzes the hydrolysis of internal β1-4 galactose linkages in unbranched, repeating poly-N-acetyllactosamine ([GlcNAc- (1-3)Gal- (1-4)] n ) structures [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 52720-51-1. Pack Sizes: 100 U. Product ID: HY-E70136. | |
| Endo-β-N-acetylglucosaminidase D | Endo-β-N-acetylglucosaminidase D (Endo D), isolated from Streptococcus pneumoniae. Endo-β-N-acetylglucosaminidase D hydrolyzes Fc N-glycan of intact IgG antibodies after sequential removal of the sialic acid, galactose, and internal GlcNAc residues in the N-glycan. Endo-β-N-acetylglucosaminidase D possesses transglycosylation activity with sugar oxazoline as the donor substrate [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Endo D. CAS No. 37278-88-9. Pack Sizes: 1 KU. Product ID: HY-E70132. | |
| Endo-β-N-acetylglucosaminidase F1 | Endo-β-N-acetylglucosaminidase F1 (Endo F1) cleaves Asparagine-linked high mannose and some hybrid oligosaccharides [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Endo F1. CAS No. 37278-88-9. Pack Sizes: 1 KU. Product ID: HY-E70135. | |
| Endo-β-N-acetylglucosaminidase F3 | Endo-β-N-acetylglucosaminidase D (Endo F3) cleaves free or Asparagine-linked triantennary oligosaccharides or α1-6 fucosylated biantennary oligosaccharides , as well as triamnnosyl chitobiose core structures [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Endo F3. CAS No. 37278-88-9. Pack Sizes: 500 U. Product ID: HY-E70134. | |
| Endomorphin 1 | Endomorphin 1, a high affinity, highly selective agonist of the μ-opioid receptor ( K i : 1.11 nM), displays reasonable affinities for kappa 3 binding sites, with K i value between 20 and 30 nM. Endomorphin 1 has antinociceptive properties [1] [2] [4]. Uses: Scientific research. Group: Peptides. CAS No. 189388-22-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-P0185. | |
| Endomorphin 1 acetate | Endomorphin 1 acetate, a high affinity, highly selective agonist of the μ-opioid receptor ( K i : 1.11 nM), displays reasonable affinities for kappa 3 binding sites, with K i value between 20 and 30 nM. Endomorphin 1 acetate has antinociceptive properties [1] [2] [4]. Uses: Scientific research. Group: Peptides. CAS No. 1276123-71-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0185A. | |
| Endomorphin 2 TFA | Endomorphin 2 TFA, a high affinity, highly selective agonist of the μ-opioid receptor , displays reasonable affinities for kappa 3 binding sites, with K i value between 20 and 30 nM [1]. Uses: Scientific research. Group: Peptides. CAS No. 1276124-00-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-P0186A. | |
| Endoproteinase Asp-N | Endoproteinase Asp-N (Asp-N) is a metalloprotease that can specifically cleave the N-terminal side of aspartyl and cysteic acid residues [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Asp-N. CAS No. 55576-49-3. Pack Sizes: 2 μg. Product ID: HY-E70196. | |
| Endoproteinase Glu-C | Endoproteinase GluC (V8 protease) is a serine proteinase. Endoproteinase GluC is able to hydrolyze some serpins and all classes of mammalian immunoglobulins [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: V8 protease; Glu-C. CAS No. 137010-42-5. Pack Sizes: 100 μg. Product ID: HY-E70194. | |
| Endoproteinase Lys-C | Endoproteinase Lys-C is a protease that cleaves proteins on the C-terminal side of lysine residues and is commonly used for protein sequencing [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 72561-05-8. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 mg; 5 mg; 10 mg. Product ID: HY-P3208. | |
| Endo S2, Streptococcus pyogenes | Endo-β-N-acetylglucosaminidase (Endo S2) is a key enzyme involved in the processing of free oligosaccharides in the cytosol. Endo-β-N-acetylglucosaminidase catalyzes hydrolysis of N-linked oligosaccharides [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 37278-88-9. Pack Sizes: 2 KU. Product ID: HY-E70069. | |
| Endothall | Endothall (Endothal) is a protein phosphatase 2A ( PP2A ) inhibitor with IC 50 s of 90 nM and 5 μM for PP2A and PP1, respectively. Endothall can be used as an herbicide. Endothall also is useful in cancer chemotherapy [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Endothal. CAS No. 145-73-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113976A. | |
| Endothelin 1 (swine, human) | Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ET A and ET B [1]. Uses: Scientific research. Group: Peptides. CAS No. 117399-94-7. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P0202. | |
| Endothelin 1 (swine, human) (TFA) | Endothelin 1 (swine, human) (TFA) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ET A and ET B [1]. Uses: Scientific research. Group: Peptides. CAS No. 394693-38-0. Pack Sizes: 500 μg; 5 mg; 10 mg. Product ID: HY-P0202A. | |
| Endoxifen | Endoxifen is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen has the potential for breast cancer study [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 110025-28-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18719E. | |
| Endoxifen E-isomer hydrochloride | Endoxifen E-isomer hydrochloride (E-Endoxifen hydrochloride), an E-isomer of Endoxifen, is an impurity in Endoxifen Z-isomer agent substance. Endoxifen E-isomer hydrochloride exhibits antiestrogenic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-Endoxifen hydrochloride. CAS No. 1197194-61-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-18719C. | |
| Endoxifen hydrochloride | Endoxifen hydrochloride is a key active metabolite of Tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen hydrochloride has the potential for breast cancer study [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1197194-41-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18719B. | |
| Enecadin | Enecadin is a neuroprotective agent extracted from patent US 8623823 B2. Uses: Scientific research. Group: Signaling pathways. CAS No. 259525-01-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100119. | |
| Enflicoxib | Enflicoxib (E 6087) is a nonsteroidal anti-inflammatory compound that selectively inhibits cyclooxygenase-2 ( COX-2 ). Enflicoxib does not inhibit cyclooxygenase-1 (COX-1). E-6087 shows anti-inflammatory, analgesic and antipyretic activities in animal models [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E 6087. CAS No. 251442-94-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19384. | |
| Enflurane | Enflurane, a volatile anaesthetic, is a potent inhibitor of high conductance Ca 2+ -activated K+ channels of Chara australis. Enflurane is an internal standard in monitoring halogenated volatile anaesthetics by headspace gas chromatography-mass spectrometry [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13838-16-9. Pack Sizes: 100 mg. Product ID: HY-A0135. | |
| Enfortumab | Enfortumab is a humanized derived anti- Nectin-4 antibody that can be conjugated with the highly efficient microtubule disruptor MMAE (HY-15162) to generate the antibody drug conjugate (ADC) Enfortumab vedotin (HY-P99016A). Enfortumab can be used for the study of locally advanced and metastatic urothelial carcinoma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1448664-46-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99016. | |
| Enfortumab vedotin-ejfv | Enfortumab vedotin-ejfv is an anti- Nectin-4 antibody-drug conjugate. Enfortumab vedotin-ejfv is a fully humanized IgG1 antibody conjugated to the microtubule disrupting agent MMAE (HY-15162) via a protease-cleavable maleimidocaproylvaline-citrulline linker (SGD-1006). Nectin-4 is an adhesion protein involved in cellular processes and tumorigenesis, and Enfortumab vedotin-ejfv is indicated for the inhibition of locally advanced or metastatic urothelial carcinoma [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1346452-25-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99016A. | |
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