MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| δ-Tocotrienol | δ-Tocotrienol is a Vitamin E in vegetables, fruits, seeds, nuts, grains and oils. Vitamin E has become well known for its role as an antioxidant, in lowering cholesterol and other lipids, as a neuroprotective and anticancer agent, and in cardiovascular disease protection. Uses: Scientific research. Group: Signaling pathways. CAS No. 25612-59-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122778. |  |
| delta-Valerobetaine | delta-Valerobetaine is a precursor of trimethylamine N-oxide (TMAO). Uses: Scientific research. Group: Natural products. CAS No. 6778-33-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114202. | |
| Demcizumab | Demcizumab (OMP 21M18) is an anti- DLL4 monoclonal antibody. Demcizumab is a potent inhibitor of the Notch pathway. Demcizumab alone or in combination with chemotherapy is effective in various cancer models [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: OMP 21M18; Human Anti-TNFRSF10B Recombinant Antibody. CAS No. 1243262-17-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99261. | |
| Demecarium Bromide | Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor, with an apparent affinity ( K iapp ) of 0.15 μM [1]. Demecarium Bromide (BC-48) is used as a glaucoma agent [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BC-48. CAS No. 56-94-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1626A. | |
| Demeclocycline | Demeclocycline is an orally active tetracycline antibiotic. Demeclocycline impairs protein synthesis by binding to the 30S ribosomal subunit to inhibit binding of aminoacyl tRNA. Demeclocycline shows anti-bacterial activitise to a wide variety of bacterial infections [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 127-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121268. | |
| Demeclocycline hydrochloride | Demeclocycline hydrochloride is a tetracycline antibiotic , which is found in a mutant strain of Streptomyces aureofaciens. Demeclocycline hydrochloride is promising for research of Lyme disease, acne, chronic inappropriate antidiuretic hormone secretion and bronchitis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 64-73-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17560. | |
| Demecolcine | Demecolcine is a potent mitotic inhibitor with an IC 50 value of 2.4 μM for inhibition of tubulin polymerization. Colcemid (Demecolcine) can interact with tubulin dimers to induce anti-mitotic action and inhibit microtubule growth. Colcemid (Demecolcine) can be used for inflammatory disorders and cancer research [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 477-30-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0282. | |
| Demethoxycurcumin | Demethoxycurcumin is one of the main active ingredients of curcumin, which has anti-inflammatory, antioxidant, antibacterial, anti-cancer and neuroprotective effects. Demethoxycurcumin is orally active. Demethoxycurcumin can be used in inflammation, cancer and Alzheimer's disease research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Curcumin II; Desmethoxycurcumin; Monodemethoxycurcumin. CAS No. 22608-11-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-N0006. | |
| Demethoxydeacetoxypseudolaric acid B | Demethoxydeacetoxypseudolaric acid B is a metabolite of the glucoside of pseudolaric acid C2 (PC2) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Deacetyldemethylpseudolaric acid B. CAS No. 82508-36-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N3697. | |
| Demethylcephalotaxinone | Demethylcephalotaxinone is an alkaloid. Demethylcephalotaxinone can be isolated from Hainan cycad ( C. hainanensis ) [1]. Uses: Scientific research. Group: Natural products. CAS No. 51020-45-2. Pack Sizes: 1 mg. Product ID: HY-N3721. | |
| Demethyleneberberine | Demethyleneberberine is a natural mitochondria-targeted antioxidant. Demethyleneberberine alleviates mice colitis and inhibits the inflammatory responses by inhibiting NF-κB pathway and regulating the balance of Th cells. Demethyleneberberine could serve as a AMPK activator for treating non-alcoholic fatty liver disease (NAFLD) [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 25459-91-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0592. | |
| Demethyleneberberine chloride | Demethyleneberberine chloride is a natural mitochondria-targeted antioxidant. Demethyleneberberine chloride alleviates mice colitis and inhibits the inflammatory responses by inhibiting NF-κB pathway and regulating the balance of Th cells. Demethyleneberberine chloride could serve as a AMPK activator for researching non-alcoholic fatty liver disease (NAFLD) [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 16705-03-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0592A. | |
| Demethylzeylasteral | Demethylzeylasteral is an orally active triterpenoid compound isolated from Tripterygium wilfordii, which has functions such as anti-inflammatory, anti-tumor, anti fertility, estrogen metabolism regulation, immune suppression, and immune system regulation [1][2].. Uses: Scientific research. Group: Natural products. CAS No. 107316-88-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0587. | |
| Demoxepam | Demoxepam is a major metabolite of Chlordiazepoxide. Demoxepam exhibits cytotoxicity activity against cancer cell lines. Demoxepam has anticonvulsant and anxiolytic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 963-39-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-136591. | |
| Denatonium benzoate | Denatonium benzoate (THS-839) is known as the most bitter compound and is commonly used as a deterrent (bittering agent) to activate different types of bitter taste receptors ( TAS2Rs ) with oral activity. Denatonium benzoate can enhance insulin secretion, has anti-inflammatory effects, and promotes allergy susceptibility [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: THS-839. CAS No. 3734-33-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1146. | |
| Denatonium (benzoate) (Standard) | Denatonium (benzoate) (Standard) is the analytical standard of Denatonium (benzoate). This product is intended for research and analytical applications. Denatonium benzoate (THS-839) is the most bitter compound known, commonly used as an aversion agent (bitter agent) to prevent inappropriate ingestion, used in denatured alcohol, antifreeze, nail biting prevention, respirator mask fit testing , animal repellents, liquid soaps and shampoos. Uses: Scientific research. Group: Signaling pathways. CAS No. 3734-33-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1146R. | |
| Denbufylline | Denbufylline (BRL 30892) is an inhibitor of phosphodiesterase-4 ( PDE4 ). Denbufylline is able to block the degradation of intracellular cAMP (cyclic adenosine phosphate) thereby increasing the level of intracellular cAMP, which helps regulate a variety of cellular functions. Denbufylline can be used in the study of chronic obstructive pulmonary disease (COPD), asthma and other inflammatory diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL 30892. CAS No. 57076-71-8. Pack Sizes: 5 mg. Product ID: HY-130786. | |
| Dendrobine | Dendrobine is an alkaloid isolated from Dendrobium nobile. Dendrobine possesses antiviral activity against influenza A viruses , with IC 50 s of 3.39 μM, 2.16 μM and 5.32 μM for A/FM-1/1/47 (H1N1), A/Puerto Rico/8/34 H274Y (H1N1) and A/Aichi/2/68 (H3N2), respectively. Dendrobine activates the JNK/p38/Nrf2 signaling pathway. Dendrobine exhibits antiviral, antitumor, anti-inflammatory, and neuroprotective properties [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 2115-91-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0638. | |
| Denifanstat | Denifanstat (TVB-2640) is an orally active and potent Fatty Acid Synthase (FASN) inhibitor with an IC 50 of 0.052 μM and an EC 50 of 0.072 μM. Denifanstat has the potential for fatty liver disease and cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TVB-2640; FASN-IN-2; ASC-40. CAS No. 1399177-37-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-112829. | |
| Denintuzumab | Denintuzumab (hBU 12) is a recombinant humanized anti-CD19 monoclonal antibody. Denintuzumab can be used as the antibody moiety ( ADC antibody ) of antibody-drug conjugates to synthesize ADC, Denintuzumab Mafodotin (SGN-CD19A). Denintuzumab Mafodotin can be used in the research of acute lymphoblastic leukemia [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: hBU 12. CAS No. 1630074-14-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99285. | |
| Denosumab | Denosumab is a human monoclonal antibody that targets the protein RANKL. Denosumab binds to the receptor activator of nuclear factor kappa-B ligand (RANKL) and prevents its binding to the RANK receptor ( K D of 0.003 nM for human RANKL). Denosumab promotes proliferation and spermatogenesis. Denosumab prevents bone resorption through inhibition of the NF-κB pathway. Denosumab can be used in bone-related studies [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG-162. CAS No. 615258-40-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9958. | |
| Denosumab (anti-TNFSF11) | Denosumab (anti-TNFSF11) is a human monoclonal antibody that targets the protein RANKL. Denosumab binds to the receptor activator of nuclear factor kappa-B ligand (RANKL) and prevents its binding to the RANK receptor (KD of 0.003 nM for human RANKL). Denosumab promotes proliferation and spermatogenesis. Denosumab prevents bone resorption through inhibition of the NF-?B pathway. Denosumab can be used in bone-related studies[1][2][3][4][5][6][7]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 615258-40-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9958A. | |
| De-N-sulfated heparin sodium salt | De-N-sulfated heparin (Heparin I-H) sodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Heparamine sodium salt. CAS No. 61932-66-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W145658. | |
| Dentonin | Dentonin (AC-100) is a synthetic fragment derived from MEPE. Dentonin enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin has no significant effect to mature osteoblasts. Dentonin can be used for the research of phosphate homeostasis and bone metabolism [1]. Uses: Scientific research. Group: Peptides. Alternative Names: AC-100. CAS No. 400090-20-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2633. | |
| (-)-Denudatin B | (-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B relaxed vascular smooth muscle by inhibiting the Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels [1]. And (-)-Denudatin B has nonspecific antiplatelet action. Uses: Scientific research. Group: Natural products. Alternative Names: Denudatin B. CAS No. 87402-88-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N3729. | |
| Deoxyandrographolide | Deoxyandrographolide suppresses LPS induced increase in mRNA levels of iNOS as well as production of proinflammatory mediators TNF-α and IL-6. Deoxyandrographolide potentiates NGF-induced neurite outgrowth [1]. Uses: Scientific research. Group: Natural products. CAS No. 79233-15-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0857. | |
| Deoxyarbutin | Deoxyarbutin is an orally active tyrosinase inhibitor that can promote apoptosis of melanoma cells, enhance the vitality of mouse acinar cells, and has skin whitening and anti-tumor activity [1][2][3]. Uses: Scientific research. Group: Natural products. CAS No. 53936-56-4. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-B1461. | |
| Deoxy-bigchap | Deoxy-bigchap is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 86303-23-3. Pack Sizes: 10 mg; 25 mg. Product ID: HY-W250173. | |
| Deoxycholic acid | Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptor TGR5 [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cholanoic Acid; Desoxycholic acid. CAS No. 83-44-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0593. | |
| Deoxycholic acid sodium salt | Deoxycholic acid sodium salt (sodium deoxycholate), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptor TGR5 [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium deoxycholate. CAS No. 302-95-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-N0593A. | |
| Deoxycorticosterone | Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. Deoxycorticosterone is an agonist for O. mykiss mineralocorticoid receptor ( rtMR ) transcription with EC 50 of 0.16 nM [3]. Deoxycorticosterone could acts as an immune stimulator in fish [4]. Uses: Scientific research. Group: Natural products. CAS No. 64-85-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-113414. | |
| Deoxycorticosterone acetate | Deoxycorticosterone acetate (DOCA) is an adrenocortin, acts as a precursor to aldosterone. Deoxycorticosterone acetate is a mineralocorticoid receptor agonist. Deoxycorticosterone acetate can cause severe renal injury, including inflammation, fibrosis, glomerular damage, and proteinuria [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 11-Deoxycorticosterone acetate; DOC acetate; Cortexone acetate. CAS No. 56-47-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1472. | |
| Deoxycytidine triphosphate | Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: dCTP; 2-Deoxycytidine-5-triphosphate. CAS No. 2056-98-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-101400. | |
| Deoxycytidine triphosphate disodium | Deoxycytidine triphosphate (disodium) (dCTP (disodium); 2-Deoxycytidine-5-triphosphate (disodium)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: dCTP disodium; 2-Deoxycytidine-5-triphosphate disodium. CAS No. 102783-51-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W010771. | |
| Deoxyfuconojirimycin hydrochloride | Deoxyfuconojirimycin hydrochloride is a specific competitive inhibitor of human liver α-L-fucosidase. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 210174-73-5. Pack Sizes: 5 mg. Product ID: HY-126306. | |
| Deoxynivalenol | Deoxynivalenol, an orally active mycotoxin of the trichothecenes family, crosses the intestinal mucosa by a paracellular pathway through the tight junctions. The Deoxynivalenol transport is not affected by P-glycoprotein (PgP) or multidrug resistance-associated proteins (MRPs) inhibitors [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Vomitoxin. CAS No. 51481-10-8. Pack Sizes: 1 mg. Product ID: HY-N6684. | |
| Deoxynivalenol-13C15 | Deoxynivalenol- 13 C 15 is the 13 C labeled Deoxynivalenol [1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 911392-36-4. Pack Sizes: 25 μg (80.33 μM * 1 mL in Acetonitrile). Product ID: HY-152072S. | |
| Deoxypodophyllotoxin | Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from Anthriscus sylvestris. Deoxypodophyllotoxin, targets the microtubule , has a major impact in oncology not only as anti-mitotics but also as potent inhibitors of angiogenesis [1]. Deoxypodophyllotoxin induces cell autophagy and apoptosis [2]. Deoxypodophyllotoxin evokes increase of intracellular Ca 2+ concentrations in DRG neurons [3]. Uses: Scientific research. Group: Natural products. CAS No. 19186-35-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2500. | |
| Deoxypyridinoline | Deoxypyridinoline is an endogenous metabolite present in Urine that can be used for the research of Heart Failure [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 83462-55-9. Pack Sizes: 1 mg. Product ID: HY-113495. | |
| Deoxyribonuclease II | Deoxyribonuclease II (DNase II) is an endonuclease that hydrolyzes the phosphodiester bonds of deoxyribonucleotides in native and denatured DNA, producing 3' phosphate and 5'-hydroxyl termini. Deoxyribonuclease II works best at acidic pH and is commonly used in biochemical research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DNase II. CAS No. 9025-64-3. Pack Sizes: 40 KU. Product ID: HY-P2863. | |
| Deoxythymidine-5'-triphosphate (trisodium) solution (100mM) | Deoxythymidine-5'-triphosphate (dTTP) trisodium solution (100mM) is one of the four nucleoside triphosphates used in the synthesis of DNA [1]. Uses: Scientific research. Group: Natural products. Alternative Names: dTTP (trisodium) solution (100mM). CAS No. 27821-54-1. Pack Sizes: 5.48 mg (100 mM * 100 μL in Water); 10.96 mg (100 mM * 200 μL in Water); 27.4 mg (100 mM * 500 μL in Water); 54.81 mg (100 mM * 1000 μL in Water). Product ID: HY-W013715A. | |
| Deoxyvasicinone | Deoxyvasicinone is an alkaloid compound isolated from plants [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 9-Oxodeoxypeganine; Pegenone. CAS No. 530-53-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N3735. | |
| Depatuxizumab | Depatuxizumab is a brain-penetrant and humanized tumor-specific anti EGFR monoclonal antibody. Depatuxizumab inhibits the growth of xenograft models of mutant EGFRvIII and wild-type EGFR. Depatuxizumab can be used for research on cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABT-806. CAS No. 1471999-69-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99849. | |
| Depatuxizumab mafodotin | Depatuxizumab mafodotin is an antibody-drug conjugate ( ADC ) that specifically targets the epidermal growth factor receptor ( EGFR ). Depatuxizumab mafodotin can be used for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-414. CAS No. 1585973-65-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132259. | |
| DEPC-Treated Water | DEPC-Treated Water is ultrapure water that has been sterilized by high temperature and high pressure and does not contain nuclease. It can avoid contamination by non-specific endonucleases and exonucleases and does not affect RNase activity[1]. Uses: Scientific research. Group: Biochemical assay reagents. Pack Sizes: 500 mL. Product ID: HY-156262. | |
| Depemokimab | Depemokimab (GSK-3511294) is a long-acting anti- IL-15 monoclonal antibody. Depemokimab can be used for research of asthma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GSK-3511294. CAS No. 2243274-14-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99850. | |
| Dephospho-CoA | Dephospho-CoA is a key intermediate in the biosynthesis of coenzyme A (CoA) , which is catalyzed by GTP-dependent dephospho-CoA kinase (DPCK) to generate CoA. Dephospho-CoA completes the final synthesis step of CoA through phosphorylation reaction and participates in energy metabolism and cell signaling. Dephospho-CoA can be used in research including cancer (such as regulating cell proliferation) and metabolic diseases (such as mitochondrial dysfunction) [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 3633-59-8. Pack Sizes: 5 mg. Product ID: HY-137899. | |
| DEPMPO | cDEPMPO is a potent anticancer proagent. High concentrations of DEPMPO spin-trap the ·OH radical together with aryl radicals arising from one-electron reduced BTO (benzotriazine 1,4-di-N-oxide) compounds[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 157230-67-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120976. | |
| Deprodone propionate | Deprodone propionate (RD20000) is a corticosteroid which is obtained by esterifying with propionic acid the 17-position of the prednisolone skeleton and deoxidating its 21-position. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RD20000. CAS No. 20424-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00190. | |
| Dequalinium Chloride | Dequalinium chloride is an Apamin (HY-P0256)-sensitive potassium channel selective blocker. Dequalinium chloride is a cationic, lipophilic mitochondrial poison. Dequalinium chloride is also an antagonist pf α7 nAChR , and an anti-microbial antiseptic agent with a broad bactericidal and fungicidal activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 522-51-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0567. | |
| Deracoxib | Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC 046; SC 46; SC 59046. CAS No. 169590-41-4. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17509. | |
| Deramciclane | Deramciclane has a high affinity for 5-HT 2A and 5-HT 2C receptors; it acts as an antagonist at both receptor subtypes and has inverse agonist properties at the 5-HT 2C receptors without direct stimulatory agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EGIS-3886. CAS No. 120444-71-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101630. | |
| Derazantinib | Derazantinib (ARQ-087) is an ATP competitive and orally active FGFR inhibitor ( IC 50 s: 1.8 nM for FGFR2, 4.5 nM for FGFR1 and 3 nM). Derazantinib inhibits FGFR phosphorylation. Derazantinib inhibits tumor growth in multiple xenograft models [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARQ-087. CAS No. 1234356-69-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19981. | |
| Derazantinib Racemate | Derazantinib Racemate (ARQ-087 Racemate) is the racemate of Derazantinib. Derazantinib is an orally bioavailable, ATP competitive tyrosine kinase inhibitor; exhibits potent activity against FGFR1-3 chondrocytes with IC 50 s of 4.5, 1.8, and 4.5 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARQ-087 Racemate. CAS No. 2309668-44-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 2 mg. Product ID: HY-19981A. | |
| Dermaseptin | Dermaseptin, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration [1]. Uses: Scientific research. Group: Peptides. CAS No. 136212-91-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0263. | |
| Dermaseptin TFA | Dermaseptin TFA, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration [1]. Uses: Scientific research. Group: Peptides. CAS No. 646451-06-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0263A. | |
| Dermatan sulphate sodium | Dermatan sulphate sodium is an oral active glycosaminoglycan and thrombin inactivator with antithrombotic activity. It selectively catalyzes the heparin cofactor II-mediated inactivation of thrombin without interacting with antithrombin III. Dermatan sulphate sodium promotes stem cell differentiation, exhibits high bioavailability, and alleviates pulmonary fibrosis injury induced by Bleomycin (HY-108345). Dermatan sulphate sodium can be used in research related to cardiovascular diseases, inflammation, and stem cell differentiation [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 54328-33-5. Pack Sizes: 5 mg. Product ID: HY-N8278. | |
| Dermorphin | Dermorphin is a natural heptapeptide μ-opioid receptor ( MOR ) agonist found in amphibian skin. Inhibition of neuropathic pain [1]. Uses: Scientific research. Group: Peptides. CAS No. 77614-16-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P0244. | |
| Dersimelagon | Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor ( MC1R ) agonist with EC 50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon shows good affinity for hMC1R and hMC4R with K i values of 2.26, 32.9 nM, respectively. Dersimelagon can be used for the research of skin pigmentation [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MT-7117. CAS No. 1835256-48-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-109114. | |
| Deruxtecan | Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MC-GGFG-DXD. CAS No. 1599440-13-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13631E. | |
| D-erythro-MAPP | D-erythro-MAPP (D-e-MAPP) is a ceramidase inhibitor, with an IC 50 of 1-5 μM in vitro [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-e-MAPP. CAS No. 143492-38-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-137422. | |
| D-Erythrose 4-phosphate sodium | D-Erythrose 4-phosphate sodium is a phosphate sodium of the simple sugar Erythrose. Erythritol is actually converted into D-Erythrose 4-phosphate that involves three isomerases [1]. Uses: Scientific research. Group: Natural products. CAS No. 103302-15-4. Pack Sizes: 1 mg. Product ID: HY-N7386A. | |
| D-erythro-Sphingosine | D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC 50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Erythrosphingosine; erythro-C18-Sphingosine; trans-4-Sphingenine. CAS No. 123-78-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101047. | |
| D-erythro-Sphingosine-d7 | D-erythro-Sphingosine-d 7 is the deuterium labeled D-erythro-Sphingosine. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Erythrosphingosine-d7; erythro-C18-Sphingosine-d7; trans-4-Sphingenine-d7. CAS No. 1246304-34-6. Pack Sizes: 500 μg. Product ID: HY-101047S. | |
| D-erythro-Sphingosine hydrochloride | D-erythro-Sphingosine (Erythrosphingosine) hydrochloride is a specific TRPM3 activator. D-erythro-Sphingosine also induces retinoblastoma protein dephosphorylation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Erythrosphingosine hydrochloride; erythro-C18-Sphingosine hydrochloride; trans-4-Sphingenine hydrochloride. CAS No. 2673-72-5. Pack Sizes: 25 mg; 50 mg. Product ID: HY-W089922. | |
| Desacetylcefotaxime | Desacetylcefotaxime, the in vivo metabolite of Cefotaxime (CTX), possesses significant in vitro antimicrobial activity similar to the parent compound against a variety of aerobic and anaerobic bacteria [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66340-28-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-126129. | |
| Desacetylcephapirin sodium | Desacetylcephapirin sodium (Deacetylcephapirin sodium) is an active metabolite of Cephapirin (HY-A0153A). Desacetylcephapirin sodium has antimicrobial against S. aureus and coagulase-negative staphylococci mastitis pathogen [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Deacetylcephapirin sodium. CAS No. 104557-24-6. Pack Sizes: 2.5 mg. Product ID: HY-131989. | |
| [Des-Arg9]-Bradykinin acetate | [Des-Arg9]-Bradykinin acetate is a Bradykinin B 1 receptor agonist that displays selectivity for B 1 over B 2 receptors. Uses: Scientific research. Group: Peptides. CAS No. 23827-91-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0298A. | |
| Desbutyl Lumefantrine | Desbutyl Lumefantrine is a metabolite of lumefantrine with antimalarial activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Desbutyl-benflumetol. CAS No. 355841-11-1. Pack Sizes: 1 mg. Product ID: HY-12781. | |
| Deschloroclozapine | Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. [11C]-Deschloroclozapine is developed as a promising PET tracer for DREADD imaging[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1977-7-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-42110. | |
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