MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
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Ecdysone
Ecdysone (α-Ecdysone), a major steroid hormone in insects and herbs, triggers mineralocorticoid receptor (MR) activation and induces cellular apoptosis. Ecdysone plays essential roles in coordinating developmental transitions and homeostatic sleep regulation through its active metabolite 20-hydroxyecdysone (Crustecdysone; 20E; HY-N6979) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: α-Ecdysone. CAS No. 3604-87-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0179.
Echinacoside
Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche deserticola , effectively inhibits Wnt/β-catenin signaling. Echinacoside elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Antiosteoporotic activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 82854-37-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0020.
Ecleralimab
Ecleralimab (CSJ-117; NVP-CSJ117) is a Fab-IgG1-λ2 antibody targeting the thymic stromal lymphopoietin TSLP. The expression system of Ecleralimab is usually CHO (Chinese Hamster Ovary) cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CSJ-117; NVP-CSJ117. CAS No. 2415207-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99872.
Eclitasertib
Eclitasertib (DNL-758) is a potent receptor-interacting protein kinase 1 (RIPK1) inhibitor with an IC 50 of 0.0375 μΜ [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DNL-758; SAR-443122. CAS No. 2125450-76-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114371.
Ecnoglutide
Ecnoglutide (XW003) is a long-acting, cAMP-biased glucagon-like peptide 1 (GLP-1) receptor agonist. Ecnoglutide can be used for research of T2DM and obesity [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: XW003. CAS No. 2459531-73-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3366.
Econazole
Econazole is an antifungal compound. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Econazol. CAS No. 27220-47-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B0885.
Econazole nitrate
Econazole nitrate is an imidazole class antifungal medication [1]. Econazole nitrate also has antibacterial activity [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24169-02-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0453.
Ecopipam hydrobromide
Ecopipam (SCH 39166) hydrobromide is a potent, selective and orally active antagonist of dopamine D1/D5 receptor , with K i s of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrobromide shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (K i =0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam hydrobromide can be used for the research of schizophrenia and obesity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 39166 hydrobromide. CAS No. 2587360-22-1. Pack Sizes: 1 mg. Product ID: HY-110033.
Ecopipam hydrochloride
Ecopipam (SCH 39166) hydrochloride is a potent, selective and orally active antagonist of dopamine D1/D5 receptor , with K i s of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrochloride shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (K i =0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam hydrochloride can be used for the research of schizophrenia and obesity [1] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 39166 hydrochloride. CAS No. 190133-94-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14689.
Ecromeximab
Ecromeximab (KM 871; KW 2871) is a mouse-derived IgG-κ chimeric antibody targeting ganglioside GD3. Ecromeximab is expressed by YB2/0 rat hybridoma cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: KM 871; KW 2871. CAS No. 292819-64-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99873.
Ectoine
Ectoine is a natural cell protectant, an amino acid derivate produced by bacteria living under extremely harsh environmental conditions. Ectoine serves as an osmoregulatory compatible solute, increasing the hydration of the skin surface and stabilizing lipid layers, which is useful in skincare. Ectoine demonstrates a good safety profile for the treatment of allergic rhinitis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 96702-03-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-107784.
Eculizumab
Eculizumab (Anti-Human C5, Humanized Antibody) is a long-acting humanized monoclonal antibody targeted against complement C5. Eculizumab inhibits the cleavage of C5 into C5a and C5b and hence inhibits deployment of the terminal complement system including the formation of membrane attack complex (MAC). Eculizumab has the potential for haemolysis research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human C5, Humanized Antibody. CAS No. 219685-50-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9914.
EDANS
EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET) [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 1,5-EDANS. CAS No. 50402-56-7. Pack Sizes: 100 mg. Product ID: HY-D1080.
Edaravone
Edaravone is a strong novel free radical scavenger, and inhibits MMP -9-related brain hemorrhage in rats treated with tissue plasminogen activator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCI-186. CAS No. 89-25-8. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g; 25 g. Product ID: HY-B0099.
Edaravone-d5
Edaravone-d 5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: MCI-186-d5. CAS No. 1228765-67-0. Pack Sizes: 1 mg. Product ID: HY-B0099S.
Edaravone (Standard)
Edaravone (Standard) is the analytical standard of Edaravone. This product is intended for research and analytical applications. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Uses: Scientific research. Group: Signaling pathways. CAS No. 89-25-8. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B0099R.
Edasalonexent
Edasalonexent (CAT-1004) is an orally bioavailable NF-κB inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CAT-1004. CAS No. 1204317-86-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17630.
Edelfosine
Edelfosine (ET-18-OCH3) is a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 Death receptor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ET-18-OCH3. CAS No. 70641-51-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108610A.
Edivoxetine hydrochloride
Edivoxetine (hydrochloride) is a selective and potent norepinephrine reuptake inhibitor (NERI) being used in depressive disorder or attention-deficit/hyperactivity disorder. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY 2216684 hydrochloride. CAS No. 1194374-05-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15413A.
Edonerpic maleate
Edonerpic maleate is a novel neurotrophic agent which can inhibit amyloid-β peptides ( Aβ ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: T-817 maleate; T-817MA. CAS No. 519187-97-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17631A.
Edotreotide
Edotreotide is a somatostatin analogue. Edotreotide bound to various radionuclides, has the potential for the research and diagnosis of certain types of cancer [1]. Edotreotide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. Alternative Names: DOTATOC; SDZ-SMT 487; SMT 487. CAS No. 204318-14-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106033.
Edoxaban
Edoxaban (DU-176b) is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with K i values of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban can be used in preventing thromboembolic disease research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU-176. CAS No. 480449-70-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10264.
Edoxaban-d6
Edoxaban-d 6 is deuterium labeled Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention. Edoxaban is also a weak inhibitor of thrombin and factor IXaβ (FIXa), with Kis of 6.00 μM and 41.7 μM, respectively, exhibits >10000-fold selectivity for FXa. Edoxaban has antithrombotic properties and has potential for thromboembolic diseases treatment [1] [2] [3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: DU-176-d6. CAS No. 1304701-57-2. Pack Sizes: 500 μg; 1 mg. Product ID: HY-10264S.
Edoxaban tosylate
Edoxaban (DU-176b) tosylate is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with K i s of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban tosylate exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban tosylate can be used for preventing thromboembolic disease research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU-176b. CAS No. 480449-71-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-10264A.
Edoxaban tosylate monohydrate
Edoxaban (DU-176b) monohydrate is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with K i s of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban monohydrate exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban monohydrate can be used for preventing thromboembolic disease research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU-176b monohydrate. CAS No. 1229194-11-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10264B.
EDP-305
EDP-305 is an orally active, potent and selective farnesoid X receptor (FXR) agonist, with EC 50 values of 34 nM (chimeric FXR in CHO cells) and 8 nM (full-length FXR in HEK cells). EDP-305 shows a potent and consistent antifibrotic effect. EDP-305 can be used for primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH) research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1933507-63-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134988.
Edpetiline
Edpetiline is a principal alkaloid from P. eduardi. Edpetiline has significant antiinflammatory effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 32685-93-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N1921.
Edratide
Edratide (TV 4710) is a synthetic peptide of 19 amino acid based on the complementarity-determining region 1 (CDR1) of a human anti-DNA antibody that expresses a major idiotype denoted 16/6 Id. Edratide reduces the rates of apoptosis ( Apoptosis ) and down-regulates of caspase-8 and caspase-3, up-regulates Bcl-xL. Edratide has the potential for the research of systemic lupus erythematosus (SLE) [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: TV 4710. CAS No. 433922-67-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3560.
Edrecolomab
Edrecolomab (Panorex) is a murine monoclonal antibody to the cell-surface glycoprotein 17-1A , expressed on epithelial tissues and on various carcinomas. Edrecolomab shows anti-tumor activity and can be used in colorectal carcinoma research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Panorex; CO17-1A. CAS No. 156586-89-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99231.
Edrophonium chloride
Edrophonium chloride is a reversible inhibitor of acetylcholinesterase. Uses: Scientific research. Group: Signaling pathways. CAS No. 116-38-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0882.
EDTA dipotassium dihydrate
EDTA dipotassium dihydrate is a metal ion chelator that forms stable and water-soluble chelates with a variety of metal ions. EDTA dipotassium is commonly used as a blood anticoagulant, which can effectively prevent blood coagulation and maintain the morphology and function of cells in blood samples. In the industrial field, EDTA dipotassium can be used to remove the adverse effects of metal ions and prevent oxidation and deterioration caused by metal ions [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ethylenediaminetetraacetic acid dipotassium dihydrate. CAS No. 25102-12-9. Pack Sizes: 50 g; 100 g. Product ID: HY-D0836.
EDTA disodium
EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ethylenediaminetetraacetic acid disodium. CAS No. 139-33-3. Pack Sizes: 10 g; 25 g. Product ID: HY-W018746.
EDTA iron sodium
EDTA iron sodium (NaFeEDTA; Sodium iron EDTA) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ethylenediaminetetraacetic acid iron sodium. CAS No. 15708-41-5. Pack Sizes: 10 mM * 1 mL; 100 g. Product ID: HY-131926.
(E,E)-2,4-Hexadienal
(E,E)-2,4-Hexadienal is an organic compound belonging to the aldehyde class. It has a strong, pungent smell and is commonly found in a variety of foods, such as fruits and vegetables. (E,E)-2,4-Hexadienal has various applications in the food industry, especially as a flavoring agent, which helps to impart a characteristic aroma and taste to certain foods. In addition, it has potential use in inhibiting inflammatory diseases and cancer. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: trans,trans-2,4-Hexadienal. CAS No. 142-83-6. Pack Sizes: 1 mg. Product ID: HY-W068035.
(E,E)-Bisdemethoxycurcumin
(E,E)-Bisdemethoxycurcumin ((E,E)-Curcumin III) is a curcumin derivative with anti-inflammatory and anticancer activities [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: (E,E)-Curcumin III; (E,E)-Didemethoxycurcumin. CAS No. 33171-05-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0007.
EEDQ
EEDQ is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: EEDQ. CAS No. 16357-59-8. Pack Sizes: 25 g. Product ID: HY-Y1191.
EF-5
EF-5 (EF5; 2-Nitroimidazole) is a hypoxia labeling agent used to identify hypoxia in cells. Uses: Scientific research. Group: Signaling pathways. CAS No. 152721-37-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00118.
Efalizumab
Efalizumab is a targeted T cell modulator, and is a humanized monoclonal antibody of CD11a , the α subunit of LFA-1. Efalizumab inhibits T cell activation, cutaneous T cell trafficking, and T cell adhesion to keratinocytes, can be used for plaque psoriasis research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 214745-43-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9947.
Efaproxiral
Efaproxiral is a haemoglobin (Hb) synthetic allosteric modifier, decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RSR13. CAS No. 131179-95-8. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-13619.
Efaproxiral sodium
Efaproxiral sodium (RSR13 sodium) is a synthetic allosteric modifier of haemoglobin (Hb), decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RSR13 sodium. CAS No. 170787-99-2. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-13619A.
Efavaleukin alfa
Efavaleukin alfa (AMG592) is a human monoclonal antibody. Efavaleukin alfa is composed of the IGHG1 Fc fragment fused to IL-2. The expression system of Efavaleukin alfa is usually CHO (Chinese Hamster Ovary) cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG592. CAS No. 2049067-94-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99877.
Efavirenz
Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a K i of 2.93 nM and exhibits an IC 95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture [1]. Uses: Scientific research. Group: Natural products. Alternative Names: DMP 266; EFV; L-743726. CAS No. 154598-52-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10572.
Efbemalenograstim alfa
Efbemalenograstim alfa (F 627) is a recombinant fusion protein. Efbemalenograstim alfa is a long acting dimeric granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2)-Fc fragment with a peptide linker. Efbemalenograstim alfa induces the production of white blood cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Benegrastim; Bineuta; F 627. CAS No. 2200269-79-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99879.
(E)-Fenpyroximate
(E)-Fenpyroximate is a potent acaricide [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 134098-61-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0825.
Efinaconazole
Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively [1]. Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KP-103. CAS No. 164650-44-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15660.
Efineptakin alfa
Efineptakin alfa (NT-17) is a long-acting recombinant human IL-7. Efineptakin alfa supports the proliferation and survival CD4 + and CD8 + cells in both human and mice. Efineptakin alfa can be used for glioblastoma research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: NT-17. CAS No. 2026634-47-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99908.
Eflornithine
Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DFMO; MDL71782; RMI71782; α-difluoromethylornithine. CAS No. 70052-12-9. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0744.
Eflornithine hydrochloride
Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylornithine hydrochloride. CAS No. 68278-23-9. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0744A.
Eflornithine hydrochloride hydrate
Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate. CAS No. 96020-91-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0744B.
Efmarodocokin alfa
Efmarodocokin alfa is a fusion protein of human IL-22 and the IgG4 crystallizable fragment. Efmarodocokin alfa activates IL-22 signaling. Efmarodocokin alfa can be used for the research of severe COVID-19 pneumonia [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2247840-74-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99919.
Efonidipine
Efonidipine(NZ-105) is a dual T-type and L-type calcium channel blocker (CCB). Uses: Scientific research. Group: Signaling pathways. Alternative Names: NZ-105; (±)-Efonidipine. CAS No. 111011-63-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12502.
Efonidipine hydrochloride monoethanolate
Efonidipine hydrochloride monoethanolate (NZ-105 hydrochloride monoethanolate) is a dual T-type and L-type calcium channel blocker (CCB). Uses: Scientific research. Group: Signaling pathways. Alternative Names: NZ-105 hydrochloride monoethanolate. CAS No. 111011-76-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12502A.
Efruxifermin
Efruxifermin is an Fc-FGF21 fusion protein (human IgG1 Fc domain linked to a modified human FGF21). Efruxifermin has prolonged half-life and enhanced receptor affinity compared with native human FGF21. Efruxifermin can be used for the research of non-alcoholic steatohepatitis [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2375240-92-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99930.
Eftilagimod alfa
Eftilagimod alfa (IMP321) is a recombinant LAG-3Ig fusion protein that binds to MHC class II. Eftilagimod alfa mediates antigen-presenting cell (APC) activation followed by CD8 T-cell activation. Eftilagimod alfa can be used for metastatic melanoma and metastatic breast carcinoma research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IMP321; LAG-3Ig. CAS No. 1800476-36-1. Pack Sizes: 1 mg. Product ID: HY-P99933.
Eftozanermin alfa
Eftozanermin alfa (ABBV-621) is a second-generation tumor necrosis factor-related apoptosis-inducing ligand receptor ( TRAIL-R ) agonist. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors 4/5. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABBV-621. CAS No. 1820660-69-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99934.
EG1
EG1, a specific Pax2 inhibitor, directly binds the paired domain of Pax2 ( K d =1.35-1.5 μM) and inhibits Pax2-DNA interactions. EG1 can inhibit embryonic kidney development, a process directly dependent on Pax2 activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 693241-54-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124838.
EGA
EGA is an inhibitor that selectively targets the endosomal trafficking pathways. EGA targets the proteins involved in the endosomal trafficking pathways through which multiple toxins and viruses enter cells. EGA exerts its activity by inhibiting the trafficking from early endosomes to late endosomes, blocking the entry of multiple acid-dependent bacterial toxins and viruses into mammalian cells and delaying the lysosomal targeting and degradation of EGFR [1]. X. Uses: Scientific research. Group: Signaling pathways. CAS No. 415687-81-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-125168.
Egalognastat
Egalognastat is a specific and orally active O-GlcNAcase (OGA) enzyme inhibitor with IC 50 value of 10.2 nM. Egalognastat can be used for the research of neurodegenerative diseases, such as tauopathies and α-synucleinopathies [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASN90. CAS No. 1884154-02-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156586.
Eganelisib
Eganelisib (IPI549) is a potent and selective PI3Kγ inhibitor with an IC 50 of 16 nM. Eganelisib shows >100-fold selectivity over other lipid and protein kinases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IPI-549. CAS No. 1693758-51-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100716.
EGFR-IN-24
EGFR-IN-24, a potent EGFR inhibitor, shows inhibition against EGFR(del19/T790M/C797S) and EGFR(L858R/T790M/C797S), respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2757548-54-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-142512.
EGFR-IN-47
EGFR-IN-47 is a potent and orally active EGFR L858R/T790M/C797S inhibitor with an IC 50 of 0.01 μM. EGFR-IN-47 induces cell cycle attest and cell apoptosis. EGFR-IN-47 has the potential for the research of NSCLC [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3034649-73-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143337.
EGFR-IN-5
EGFR-IN-5 is a EGFR inhibitor with IC 50 s of 10.4, 1.1, 34, 7.2 nM for EGFR, EGFR L858R , EGFR L858R/T790M , and EGFR L858R/T790M/C797S , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 2225887-26-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111415.
EGFR-IN-69
EGFR-IN-69 (compound 17g) is a potent EGFR inhibitor, with IC 50 values of 4.3, 6.6 and 25.6 nM against EGFR L858R/T790M/C797S , EGFR L858R/T790M , and EGFR 19del/T790M/C797S , respectively. EGFR-IN-69 can be used for non-small-cell-lung-cancer (NSCLC) research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2433837-65-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150610.
EGFR-IN-70
EGFR-IN-70 (compound 18j) is a potent EGFR inhibitor with IC 50 values of 23.6 and 307.5 nM for EGFR LR/TM/CS and EGFR WT , respectively. EGFR-IN-70 has anti-proliferative activity and suppresses phosphorylation of the EGFR. EGFR-IN-70 can be used for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2926716-96-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150611.
EGFR-IN-78
EGFR-IN-78 (compound A5), a 2-aminopyrimidine derivative, is a reversible inhibitor of EGFR C797S -TK, and also an inducer of apoptosis. EGFR-IN-78 shows anti-proliferative activity, inhibits EGFR phosphorylation and arrests cell cycle at G2/M phase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3042104-73-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-149889.
EGFR-IN-8
EGFR-IN-8 is a dual EGFR and c-Met inhibitor, compound 48. EGFR-IN-8 can be a promising candidate for further development to target EGFR TKI-resistant NSCLC [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2407957-87-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126320.
EGFR-IN-86
EGFR-IN-86 (compound 4i) is an EGFR inhibitor ( IC 50 : 1.5 nM) with high activity against glioblastoma. EGFR-IN-86 induces apoptosis and arrests the U87 cell cycle in the G2/M phase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3055550-22-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149530.
EGFR-IN-89
EGFR-IN-89 (compound 13k) is a potent, fourth-generation EGFR mutation inhibitor with an IC 50 of 10.1 nM against Del19/T790M/C797S mutations. EGFR-IN-89 shows higher selectivity over wild type [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2413029-40-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-156284.
EGFR-IN-95
EGFR-IN-95 (compound 5j) is an 2,4-diaminonicotinamide derivative. EGFR-IN-95 has potent inhibitory activity against EGFR del19/T790M/C797S and L858R/T790M/C797S [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3027135-04-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-163094.
EGFR kinase inhibitor 3
EGFR kinase inhibitor 3 (compound 2) is a bivalent ATP-allosteric EGFR kinase inhibitor with IC 50 s of <10 nM, 1.5 nM, 0.059 nM, 0.064 nM for WT EGFR, EGFR-activating mutations L858R, L858R/T790M and L858R/T790M/C797S, respectively. EGFR kinase inhibitor 3 is a C-linked inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2922402-03-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162299.