MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Deschloroclozapine dihydrochloride | Deschloroclozapine dihydrochloride, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. [11C]-Deschloroclozapine is developed as a promising PET tracer for DREADD imaging[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-42110A. |  |
| Deschloroetizolam | Deschloroetizolam is a designer Benzodiazepine. Deschloroetizolam is a psychoactive substance, with physical and cognitive effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 40054-73-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137994. | |
| Desethylamiodarone hydrochloride | Desethylamiodarone hydrochloride (N-desethylamiodarone hydrochloride) is a major active metabolite of Amiodarone. Desethylamiodarone hydrochloride is formed by CYP3A isoenzymes. Amiodarone is an antiarrhythmic agent for inhibition of ATP-sensitive potassium channel with an IC 50 of 19.1 μM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-desethylamiodarone hydrochloride; LB 33020 hydrochloride. CAS No. 96027-74-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-130353. | |
| Desfesoterodine | Desfesoterodine (PNU-200577) is a potent and selective muscarinic receptor (mAChR) antagonist with a K B and a pA 2 of 0.84 nM and 9.14, respectively [1]. Desfesoterodine is a major pharmacologically active metabolite of Tolterodine (PNU-200583; HY-A0024) and Fesoterodine (HY-70053) [2] [3]. Desfesoterodine improves cerebral infarction induced detrusor overactivity in rats [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNU-200577; 5-Hydroxymethyl Tolterodine. CAS No. 207679-81-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-76569. | |
| Desformylflustrabromine hydrochloride | Desformylflustrabromine hydrochloride is a selective agonist of α 4 β 2 neuronal nicotinic acetylcholine receptor ( nAChR ) with a pEC 50 of 6.48. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Deformylflustrabromine hydrochloride; dFBr hydrochloride. CAS No. 951322-11-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107675. | |
| Desfuroylceftiofur | Desfuroylceftiofur is an active metabolite of Ceftiofur which is a broad-spectrum cephalosporin antibiotic. Desfuroylceftiofur is active against gram-positive and gram-negative bacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120882-22-6. Pack Sizes: 1 mg. Product ID: HY-126818. | |
| Desidustat | Desidustat is an orally active HIF hydroxylase inhibitor. Desidustat can be used for the research of various disorders including anemia of different types and conditions associated with ischemia/hypoxia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZYAN1. CAS No. 1616690-16-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103227. | |
| Desipramine-d4 | Desipramine-d 4 is the deuterium labeled Desipramine[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 61361-34-0. Pack Sizes: 500 μg; 1 mg. Product ID: HY-B1272AS. | |
| Desipramine hydrochloride | Desipramine hydrochloride is an inhibitor of norepinephrine transporter ( NET ), 5-HT transporter ( SERT ) and dopamine transporter ( DAT ) with K i s of 4, 61 and 78,720 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 58-28-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1272. | |
| Desisopropylatrazine-d5 | Desisopropylatrazine-d 5 is the deuterium labeled Desisopropylatrazine[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1189961-78-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-146604S. | |
| Desloratadine | Desloratadine (Sch34117) is an orally active and selective H1 receptor antagonist ( K i =0.9 nM) with anti-inflammatory and anti-allergic activities. Desloratadine inhibits the release of histamine and LTC4 from human basophils and targets the regulatory signals of IL-4 and IL-13 production in basophils. Desloratadine significantly alleviates SAR symptoms in patients with concurrent asthma and can be used in the study of seasonal allergic rhinitis and chronic idiopathic urticaria [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Sch34117. CAS No. 100643-71-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-B0539. | |
| Desmethyl Erlotinib | Desmethyl Erlotinib (OSI-420 free base) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor [1]. Desmethyl Erlotinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OSI-420 free base; CP-373420. CAS No. 183321-86-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13256A. | |
| Desmethyl Erlotinib hydrochloride | Desmethyl Erlotinib hydrochloride (OSI-420) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor [1]. Desmethyl Erlotinib (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OSI-420; CP-373420 hydrochloride. CAS No. 183320-51-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13256. | |
| Desmethylflunitrazepam | Desmethylflunitrazepam (Norflunitrazepam) is a compound from the benzodiazepine family and is an active metabolite of Flunitrazepam [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Norflunitrazepam; Ro 05-4435. CAS No. 2558-30-7. Pack Sizes: 1 mg. Product ID: HY-114876. | |
| Desmosterol | Desmosterol is a cholesterol-like molecule. In the Bloch pathway of cholesterol biosynthesis, Desmosterol is a direct precursor of cholesterol. As an endogenous metabolite, Desmosterol is used to study cholesterol metabolism [1]. Desmosterol is an LXR activator and SREBP inhibitor, which can suppress macrophage inflammasome activation and prevent vascular inflammation and atherosclerosis. A reduction in Desmosterol promotes the production of mitochondrial reactive oxygen species ( ROS ) in macrophages and pyrin domain-dependent inflammasome activation of NLRP3. Desmosterol holds potential for research in inflammation, metabolism, and cardiovascular diseases [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 313-04-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113224. | |
| Desmosterol-d6 | Desmosterol-d 6 is the deuterium labeled Desmosterol. Desmosterol is a molecule similar to cholesterol. Desmosterol is the immediate precursor of cholesterol in the Bloch pathway of cholesterol biosynthesis. Desmosterol, as an endogenous metabolite, used to study cholesterol metabolism[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1246298-67-8. Pack Sizes: 500 μg; 1 mg. Product ID: HY-113224S. | |
| Desogestrel | Desogestrel (Org-2969) is a third-generation progesterone analogue contained in many oral contraceptive preparations. Desogestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Org-2969. CAS No. 54024-22-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12516. | |
| Desonide | Desonide is a non-fluorinated corticosteroid anti-inflammatory agent that acts on glucocorticoid receptors. Uses: Scientific research. Group: Signaling pathways. CAS No. 638-94-8. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0248. | |
| Desoximetasone | Desoximetasone (Topicort) is a corticosteroid that can be used to relieve various skin conditions such as rashes. Uses: Scientific research. Group: Signaling pathways. CAS No. 382-67-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17570. | |
| Desoxycorticosterone pivalate | Desoxycorticosterone pivalate (DOCP) is a mineralocorticoid hormone and an analog of Desoxycorticosterone. Desoxycorticosterone pivalate is used for the management of canine hypoadrenocorticism [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 808-48-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107917. | |
| Desthiobiotin-Iodoacetamide | Desthiobiotin-Iodoacetamide can be used as an ADC Linker. Desthiobiotin-Iodoacetamide also acts as a probe used to label the the Oridonin (HY-N0004)-treated cell lysis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2924824-04-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150230. | |
| Desthiobiotin polyethyleneoxide iodoacetamide | Desthiobiotin polyethyleneoxide iodoacetamide is useful for cysteine labeling in chemoproteomic experiments[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-143205. | |
| Destruxin B | Destruxin B, isolated from entomopathogenic fungus Metarhizium anisopliae , is one of the cyclodepsipeptides with insecticidal and anticancer activities. Destruxin B induces apoptosis via a Bcl-2 Family -dependent mitochondrial pathway in human nonsmall cell lung cancer cells [1]. Destruxin B significantly activates caspase-3 and reduces tumor cell proliferation through caspase-mediated apoptosis , not only in vitro but also in vivo [2]. Uses: Scientific research. Group: Natural products. CAS No. 2503-26-6. Pack Sizes: 1 mg. Product ID: HY-N6690. | |
| Desvenlafaxine | Desvenlafaxine, the succinate salt form of the isolated major active metabolite of Venlafaxine (HY-B0196), is an orally active and BBB penetrated 5-HT and norepinephrine reuptake inhibitor, with IC 50 values of 47.3 nM and 531.3 nM for hSERT and hNET, respectively. Desvenlafaxine shows weak binding affinity (62% inhibition at 100 μM) at the human dopamine (DA) transporter [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: O-Desmethylvenlafaxine. CAS No. 93413-62-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0602. | |
| Desvenlafaxine succinate hydrate | Desvenlafaxine succinate hydrate, the succinate salt form of the isolated major active metabolite of Venlafaxine (HY-B0196), is an orally active and BBB penetrated 5-HT and norepinephrine reuptake inhibitor, with IC 50 values of 47.3 nM and 531.3 nM for hSERT and hNET, respectively. Desvenlafaxine succinate hydrate shows weak binding affinity (62% inhibition at 100 μM) at the human dopamine (DA) transporter [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: O-Desmethylvenlafaxine succinate hydrate; Desvenlafaxine succinate monohydrate. CAS No. 386750-22-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0602A. | |
| DETA NONOate | DETA NONOate (NOC 18) is an exogenous nitric oxide (NO) donor. DETA NONOate shows a slow release normal amounts of NO and long-acting[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Diethylamine NONOate; NOC-18. CAS No. 146724-94-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136278. | |
| Deterenol hydrochloride | Deterenol hydrochloride (AL842) is a selective beta-agonist. Deterenol hydrochloride causes vasodepressor, anxiety, increasing heart rate, hypotension palpitation and respiratory distress [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AL842. CAS No. 23239-36-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W702027. | |
| Detomidine hydrochloride | Detomidine hydrochloride, an imidazole derivative, is a potent α2-adrenergic agonist. Detomidine hydrochloride produces dose-dependent analgesic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 90038-01-0. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-B0163A. | |
| Deucravacitinib | Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases, which selectively binds to TYK2 pseudokinase (JH2) domain ( IC 50 =1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain. Deucravacitinib inhibits IL-12/23 and type I IFN pathways. Deucravacitinib, the FDA's world first de novo deuterium, is available for study in moderate to severe plaque psoriasis [1] [2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: BMS-986165. CAS No. 1609392-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117287. | |
| Deupirfenidone | Deupirfenidone-d 3 -d 3 is the deuterium labeled Pirfenidone (HY-B0673)[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: LYT-100; AMR69-d3. CAS No. 1093951-85-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0673S1. | |
| Deuruxolitinib | Deuruxolitinib, a deuterated Ruxolitinib (HY-50856), is an orally active JAK1 and JAK2 inhibitor. Deuruxolitinib demonstrates significant hair regrowth effects. Deuruxolitinib can be used for the research of alopecia areata [1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: CTP-543; Ruxolitinib d8; Deuterated Ruxolitinib. CAS No. 1513883-39-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-50856S. | |
| Deutenzalutamide | Deutenzalutamide (Enzalutamide-d 3 ) is a developed deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells [1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Enzalutamide-d3; MDV3100-d3. CAS No. 1443331-82-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-70002S. | |
| Devazepide | Devazepide (L-364,718) is a potent, competitive, selective and orally active nonpeptide antagonist of cholecystokinin (CCK) receptor , with IC 50 s of 81 pM, 45 pM and 245 nM for rat pancreatic, bovine gallbladder and guinea pig brain CCK receptors, respectively. Devazepide (L-364,718) is effective for gastrointestinal disorders [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-364,718; MK-329. CAS No. 103420-77-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106301. | |
| Devimistat | Devimistat (CPI-613) is a mitochondrial metabolism inhibitor. Devimistat is a lipoic acid antagonist that abrogates mitochondrial energy metabolism to induce apoptosis in various cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPI-613. CAS No. 95809-78-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15453. | |
| Dexamethasone | Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist, apoptosis inducer, and common disease inducer in experimental animals, constructing models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and monocytes. Dexamethasone also has potential for use in COVID-19 research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hexadecadrol; Prednisolone F. CAS No. 50-02-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-14648. | |
| Dexamethasone 9,11-epoxide | Dexamethasone 9,11-epoxide, a compound extracted from patent CN 106520896 A and RU 2532902 C1, is an intermediate in the preparation of dexamethasone. Uses: Scientific research. Group: Signaling pathways. CAS No. 24916-90-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-N0348. | |
| Dexamethasone acetate | Dexamethasone acetate (Dexamethasone 21-acetate) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dexamethasone 21-acetate; Hexadecadrol acetate. CAS No. 1177-87-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-14648A. | |
| Dexamethasone palmitate | Dexamethasone palmitate (DXP) is a proagent of Dexamethasone (HY-14648). Dexamethasone palmitate can be used for the research of inflammation [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DXP. CAS No. 14899-36-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128922. | |
| Dexamethasone phosphate disodium | Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium is an orally active Glucocorticoid receptor agonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dexamethasone 21-phosphate disodium. CAS No. 2392-39-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B1829A. | |
| Dexamethasone phosphate (disodium) (Standard) | Dexamethasone phosphate (disodium) (Standard) is the analytical standard of Dexamethasone phosphate (disodium). This product is intended for research and analytical applications. Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium is an orally active Glucocorticoid receptor agonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2392-39-4. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1829AR. | |
| Dexamethasone (Standard) | Dexamethasone (Standard) is the analytical standard of Dexamethasone. This product is intended for research and analytical applications. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hexadecadrol(Standard); Prednisolone F (Standard). CAS No. 50-02-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-14648R. | |
| Dexamethasone (Water Soluble) | Dexamethasone (Hexadecadrol) Water Soluble is a water-soluble form of Dexamethasone (HY-14648). Dexamethasone is a glucocorticoid receptor agonist, apoptosis inducer, and a common disease inducer in experimental animals. It can be used to construct models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and monocytes. Dexamethasone also has the potential to be used in COVID-19 research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dexamethasone cyclodextrin complex. CAS No. 50-02-2. Pack Sizes: 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-14648C. | |
| Dexbrompheniramine | Dexbrompheniramine is an orally active H1 receptor antagonist. Dexbrompheniramine is an antihistamine that reduces the effects of natural chemical histamine. Dexbrompheniramine can be used for the research of hay fever and urticaria [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Brompheniramine; (S)-Brompheniramine. CAS No. 132-21-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-A0191. | |
| Dexchlorpheniramine maleate | Dexchlorpheniramine maleate is an orally taken anti- histamine that has anti-inflammatory, anti-irritant, anti-allergic, and skin barrier effects. Dexchlorpheniramine maleate inhibits myocardial contraction in rats. Dexchlorpheniramine maleate can be used in studies of allergic rhinitis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-(+)-Chlorpheniramine maleate salt. CAS No. 2438-32-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-B1062. | |
| Dexfadrostat | Dexfadrostat ((R)-Fadrozole) is a potent nonsteroidal inhibitor [1]. Dexfadrostat also inhibits human placental aromatase (pIC 50 = 6.17) and aldosterone biosynthesis. Dexfadrostat reverses cardiac fibrosis in spontaneously hypertensive heart failure rats. [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Fadrozole; (R)-CGS 16949A free base; FAD286. CAS No. 102676-87-9. Pack Sizes: 10 mM * 1 mL; 1 mg. Product ID: HY-113986. | |
| Dexketoprofen (trometamol) | Dexketoprofen trometamol (Dexketoprofen tromethamine salt) is an orally active non-selective COX inhibitor. Dexketoprofen trometamol has a pain-relieving effect, anti-inflammatory effect and anti-cancer effect [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dexketoprofen tromethamine salt. CAS No. 156604-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0714. | |
| Dexloxiglumide | Dexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist [1]. Dexloxiglumide, the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8) [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 119817-90-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128878. | |
| Dexmedetomidine | Dexmedetomidine ((+)-Medetomidine) is a potent, selective and orally active agonist of α2-adrenoceptor , with a K i of 1.08 nM. Dexmedetomidine shows 1620-fold selectivity against α1-adrenoceptor. Dexmedetomidine exhibits anxiolysis, sedation, and modest analgesia effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Medetomidine; (S)-Medetomidine. CAS No. 113775-47-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-12719. | |
| Dexmedetomidine hydrochloride | Dexmedetomidine hydrochloride ((+)-Medetomidine hydrochloride) is a potent, selective and orally active agonist of α2-adrenoceptor , with a K i of 1.08 nM. Dexmedetomidine hydrochloride shows 1620-fold selectivity against α1-adrenoceptor. Dexmedetomidine hydrochloride exhibits anxiolysis, sedation, and modest analgesia effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Medetomidine hydrochloride; (S)-Medetomidine hydrochloride. CAS No. 145108-58-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17034A. | |
| Dexpramipexole dihydrochloride | Dexpramipexole dihydrochloride ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and weak non-ergoline dopamine agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Pramipexole dihydrochloride; R-(+)-Pramipexole dihydrochloride; KNS-760704 dihydrochloride. CAS No. 104632-27-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17355A. | |
| Dexrazoxane | Dexrazoxane, as an intracellular iron chelating agent, reduces the formation of superoxide radicals and has cardioprotective, anti-inflammatory, antioxidant, anti-tumor and neuroprotective activities. Dexrazoxane inhibits ferroptosis of H9c2 cells by inhibiting HMGB1. Dexrazoxane induces DNA damage and apoptosis in human fibrosarcoma cells [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICRF-187; ADR-529; NSC-169780. CAS No. 24584-09-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0581. | |
| Dexrazoxane hydrochloride | Dexrazoxane hydrochloride (ICRF-187 hydrochloride) is a heart protectant that can help preserve ovarian function and fertility. Dexrazoxane hydrochloride has antioxidant and anti-inflammatory properties, can cross the blood-brain barrier, improves motor function disorders, and offers neuroprotective effects, making it useful in the study of neurodegenerative diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICRF-187 hydrochloride; ADR-529 hydrochloride; NSC-169780 hydrochloride. CAS No. 149003-01-0. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-76201. | |
| Dextran | Dextran (Dextran 40) has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Dextran 40. CAS No. 9004-54-0. Pack Sizes: 100 mg. Product ID: HY-112624. | |
| Dextran (MW 40000) | Dextran (MW 40000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds. Dextran has excellent solubility in water, making it useful as a viscosity modifier or stabilizer in foods, paints and adhesives. In the biomedical field, dextran is often used as a plasma expander because of its ability to increase blood volume when administered intravenously. It can also be modified to create dextran-based drug delivery systems, such as targeted nanoparticles. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9004-54-0. Pack Sizes: 1 g. Product ID: HY-112624C. | |
| Dextran sulfate sodium salt (MW 5000) | Dextran sulfate sodium salt (DSS) (MW 5000) is a polymer of dehydrated glucose with a molecular weight of approximately 5000. Dextran sulfate sodium salt (DSS) with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 5000) is an inhibitor of complement and coagulation pathways, and belongs to the glycosaminoglycans (GAG) family. Dextran sulfate sodium salt (MW 5000) acts as an anticoagulant, antiviral, and anti-lipemic agent. Dextran sulfate sodium salt (DSS) stops HIV-1 virus adsorption to host cells. Dextran sulfate sodium salt (MW 5000) prevents NK cell-mediated cytotoxicity. Dextran sulfate sodium salt (MW 5000) inhibits instant blood-mediated inflammatory reaction (IBMIR)[1][2][3][4][5]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DSS (MW 5000); DXS (MW 5000). CAS No. 9011-18-1. Pack Sizes: 5 g; 10 g. Product ID: HY-116282. | |
| Dextran T10 (MW 10,000) | Dextran T10 MW 10,000 (Dextran D10; Dextran T10 MW 8000-12000) is a polymer of anhydroglucose with the average molecular weight of 10000. Dextran T10 MW 10,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area[1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Dextran 10; Dextran D10; Dextran T10(MW 8000-12000). CAS No. 9004-54-0. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-112624L. | |
| Dextran T1 (MW 1,000) | Dextran T1 MW 1,000 (Dextran 1; Dextran D1; Dextran T1 MW 800-1200) is a polymer of anhydroglucose with the average molecular weight of 1000. Dextran T1 MW 1,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area[1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Dextran 1; Dextran D1; Dextran T1(MW 800-1200). CAS No. 9004-54-0. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-112624A. | |
| Dextran T500 (MW 500,000) | Dextran T500 MW 500,000 (Dextran 500; Dextran D500; Dextran T500 MW 440000-560000) is a polymer of anhydroglucose with the average molecular weight of 500,000. Dextran T500 MW 500,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area[1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Dextran 500; Dextran D500; Dextran T500(MW 440000-560000). CAS No. 9004-54-0. Pack Sizes: 50 mg; 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-112624P. | |
| Dextran T70 (MW 70,000) | Dextran 70,000 is a high molecular weight polysaccharide formed by glucose linked by ?-(1?6) glycosidic bonds. Dextran 70,000 can expand blood volume through colloidal osmotic pressure effect and inhibit cell adhesion and platelet aggregation through steric hindrance. At the same time, Dextran 70,000 can be used as a drug carrier to achieve targeted delivery through endocytosis. Dextran 70,000 is biologically inert and has low immunogenicity. It can be used for clinical blood volume expansion, anti-thrombotic research, and evaluation of vascular permeability in in vitro experiments. It can also be combined with fluorescent dyes for cell tracking and drug delivery research. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Dextran 70; Dextran D70; Dextran T70(MW 64000-76000). CAS No. 9004-54-0. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-112624B. | |
| Dextrin | Dextrins are a group of low molecular weight carbohydrates produced by the hydrolysis of starch. Dextrin is commonly used as a thickener, stabilizer or binder in a variety of foods including baked goods, beverages and confectionary. In addition, it is used in the production of adhesives, paper and textiles. Its unique chemical properties make it an important ingredient in a variety of industrial processes, especially in construction and packaging. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9004-53-9. Pack Sizes: 100 g. Product ID: HY-W115731. | |
| DFAME | DFAME is a red fluorophore (Ex=508 nm, Em=641 nm). Beetroot and Corn are dimeric fluorogenic RNA aptamers that can bind to DFAME to form Beetroot-DFAME (Kd=460nM) and Corn-DFAME (Kd= 3600nM). Beetroot-DFAME (Kd=460nM) and Corn-DFAME can be used to form RNA assemblies in living cells. Creating RNA assemblies can be used for the study of RNA Nanostructures. DNA/RNA Nanostructures would be useful in cell and gene therapy (CGT) research[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1420815-55-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W073524. | |
| DFBTA | DFBTA is an orally active, potent and little brain penetrated ANO1 (Calcium-activated chloride channel anoctamin-1) inhibitor, with an IC 50 of 24 nM. DFBTA shows analgesic efficacy for inflammatory pain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2966044-07-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146334. | |
| DFHBI | DFHBI is a small molecule that resembles the chromophore of green fluorescent protein (GFP). Spinach and DFHBI are essentially nonfluorescent when unbound, whereas the Spinach-DFHBI complex is brightly fluorescent both in vitro and in living cells. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1241390-29-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110250. | |
| DFHBI-1T | DFHBI-1T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells[1][2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1539318-36-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110251. | |
| DFHO | DFHO is a fluorogenic ligand of Corn fluorogenic aptamer. The RNA aptamer, Corn binds DFHO with a Kd value of 70 nM and converts it to a fluorescent form, enabling RNA imaging in cells[1][2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1420815-34-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-136277. | |
| DFP00173 | DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC50 of ?0.1-0.4 ?M. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 672286-03-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-126073. | |
| DFPM | DFPM activates plant resistance protein signaling in roots, and triggers root growth arrest. DFPM decreases root cell viability in accession Col-0. DFPM is light sensitive in aqueous solutions. DFPM becomes bioactive during light and oxygen-dependent modification [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 301338-95-4. Pack Sizes: 1 mg. Product ID: HY-119994. | |
| D-Fructose | D-Fructose (D(-)-Fructose) is a monosaccharide found in honey, fruits, and other plants. Two D-Fructose molecules can combine to form a disaccharide, sucrose [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: D(-)?-Fructose. CAS No. 57-48-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N7092. | |
| D-Fructose-13C | D-Fructose- 13 C is the 13 C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: D(-)?-Fructose- 13 C. CAS No. 108311-21-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7092S1. | |
| D-Fructose-13C-1 | D-Fructose- 13 C-1 is the 13 C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: D(-)?-Fructose- 13 C-1. CAS No. 117013-19-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N7092S2. | |
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