Alfa Chemistry. - Products
Alfa Chemistry is an ISO 9001:2015 Certified Supplier of various building blocks, reagents, catalysts, nanomaterials, reference materials, and research chemicals. In-stock products can be shipped quickly.
| Product | Description | |
|---|---|---|
| Fmoc-4-amino-3-hydroxybutanoic acid | Fmoc-4-amino-3-hydroxybutanoic acid (Fmoc-Ahb-OH) is a type of amino acid that contains both an amino group and a carboxyl group. It is commonly used as a building block for peptides, which are short chains of amino acids linked by peptide bonds. Uses: Fmoc-ahb-oh is widely used in the synthesis of peptides for various scientific applications. the inclusion of ahb-oh in peptide chains can result in improved bioactivity or stability of the peptides. for example, ahb-oh can be used to add hydrophilic or amphiphilic characters to peptides, which can enhance their solubility or cell penetration. ahb-oh can also be used to introduce functional groups that can be used for further modification of the peptide. Group: Amino acids. CAS No. 184763-08-4. Molecular formula: C19H19NO5. Mole weight: 341.4. Purity: Peak Area by HPLC ≥95%. IUPACName: 4-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxybutanoic acid. Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)NCC (CC (=O)O)O. Catalog: ACM184763084. |  |
| Fmoc-4-bis(2-chloroethyl)amino-L-phenylalanine | Fmoc-Phe(Cl2)2-OH is a derivative of phenylalanine, which is an essential amino acid that must be consumed from external sources. Fmoc-Phe(Cl2)2-OH is a common building block in solid-phase peptide synthesis (SPPS) because it can be selectively deprotected and coupled to other amino acids. This compound was originally synthesized in 1997 by Barral et al. and has since become a widely used tool in peptide chemistry. Uses: Fmoc-phe(cl2)2-oh is commonly used in spps to synthesize peptides with biological activity. this compound is also used in medicinal chemistry to develop new drugs and small molecules. fmoc-phe(cl2)2-oh has been used in a variety of scientific experiments, including studies of protein-protein interactions, drug discovery, and structure-activity relationship studies. Group: Amino acids. CAS No. 1217809-60-3. Molecular formula: C28H28Cl2N2O4. Mole weight: 527.4. Purity: Peak Area by HPLC ≥95%. IUPACName: (2S)-3-[4-[bis(2-chloroethyl)amino]phenyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid. Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)NC (CC4=CC=C (C=C4)N (CCCl)CCCl)C (=O)O. Catalog: ACM1217809603. | |
| Fmoc-4-cyanophenylalanine | Starting amino acid for the preparation of 4-(tetrazol-5-yl-)-phenylalanine. Literature references J. S. McMurray, et al. (2000) Tetrahedron Lett., 41, 6555. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-4-cyanophenylalanine. CAS No. 173963-93-4. Molecular formula: C25H20N2O4. Mole weight: 412.44. Catalog: ACM173963934. | |
| Fmoc-5-benzyloxy-DL-tryptophan | Fmoc-5-benzyloxy-DL-tryptophan is a derivative of tryptophan that can be used as a substrate for protein engineering, drug discovery, and as a building block for the synthesis of complex molecules. Tryptophan is an essential amino acid that plays an important role in the body, including protein synthesis, serotonin production, and as a precursor for niacin. Uses: Fmoc-5-benzyloxy-dl-tryptophan has various applications in scientific experiments, including protein engineering, drug discovery, and synthesizing complex molecules. fmoc-5-benzyloxy-dl-tryptophan can also be used as a building block for the synthesis of peptides, which can be used in drug development. Group: Amino acids. Alternative Names: 5-(Benzyloxy)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]tryptoph. CAS No. 1219348-47-6. Molecular formula: C33H28N2O5. Mole weight: 532.6. Purity: Peak Area by HPLC ≥95%. IUPACName: 2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(5-phenylmethoxy-1H-indol-3-yl)propanoic acid. Canonical SMILES: C1=CC=C (C=C1)COC2=CC3=C (C=C2)NC=C3CC (C (=O)O)NC (=O)OCC4C5=CC=CC=C5C6=CC=CC=C46. Catalog: ACM1219348476. | |
| Fmoc-5-bromo-DL-tryptophan | Fmoc-Br-Trp is a synthetic amino acid that has an Fmoc-protecting group, which is commonly used in peptide synthesis. Fmoc is a stable and easily removable amino-protecting group that provides high yields in chemical reactions. Bromine is a halogen atom that has unique chemical properties, including high electronegativity, reactivity, and isotope effect. Tryptophan is an aromatic amino acid that has a bulky indole ring and a polar side chain. This combination of Fmoc, bromine, and tryptophan makes Fmoc-Br-Trp a versatile and useful building block for peptide synthesis. Uses: Fmoc-br-trp and its derivatives have various applications in scientific experiments, including peptide synthesis, drug discovery, biomaterials, and bioimaging. Group: Amino acids. Alternative Names: 5-Bromo-N-[(9H-fluoren-9-ylmethoxy)carbonyl]tryptoph. CAS No. 925939-82-8. Molecular formula: C26H21BrN2O4. Mole weight: 505.4. Purity: Peak Area by HPLC ≥95%. IUPACName: 3-(5-bromo-1H-indol-3-yl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid. Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)NC (CC4=CNC5=C4C=C (C=C5)Br)C (=O)O. Catalog: ACM925939828. | |
| Fmoc-5-chloro-DL-tryptophan | Fmoc-5-chloro-DL-tryptophan is a derivative of tryptophan, which is a naturally occurring amino acid used to build proteins in the body. The Fmoc-5-chloro-DL-tryptophan molecule has a 5-chloro substituent on the indole ring and is often used in peptide synthesis. Uses: Fmoc-5-chloro-dl-tryptophan is commonly used in peptide synthesis and chemical modification of proteins. the compound is also used in antimicrobial and antitumor studies. Group: Amino acids. CAS No. 1219398-51-2. Molecular formula: C26H21ClN2O4. Mole weight: 460.9. Purity: Peak Area by HPLC ≥95%. IUPACName: 3-(5-chloro-1H-indol-3-yl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid. Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)NC (CC4=CNC5=C4C=C (C=C5)Cl)C (=O)O. Density: 1.4±0.1 g/cm3. Catalog: ACM1219398512. | |
| Fmoc-5-fluoro-DL-tryptophan | Fmoc-5-fluoro-DL-tryptophan is a derivative of the amino acid tryptophan. It is commonly used as a building block in peptide synthesis due to its enhanced hydrophobicity and stability compared to other tryptophan analogs. The Fmoc group is a protecting group used to protect the reactive functional groups during peptide synthesis. Uses: Fmoc-5-fluoro-dl-tryptophan has a wide range of applications in scientific research. it is commonly used as a building block in peptide synthesis and has been used to study enzyme function and to develop novel therapeutic agents such as anticancer drugs. Group: Amino acids. Alternative Names: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-5-fluorotryptophan. CAS No. 138775-55-0. Molecular formula: C26H21FN2O4. Mole weight: 444.5. Purity: Peak Area by HPLC ≥95%. IUPACName: 2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(5-fluoro-1H-indol-3-yl)propanoic acid. Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)NC (CC4=CNC5=C4C=C (C=C5)F)C (=O)O. Density: 1.4±0.1 g/cm3. Catalog: ACM138775550. | |
| Fmoc-5-hydroxy-L-tryptophan | Fmoc-5-hydroxy-DL-tryptophan is a compound that belongs to the class of amino acid derivatives. It is used as a building block for the synthesis of peptides and proteins with specific biological properties. The abbreviation Fmoc stands for fluorenylmethoxycarbonyl, which is a protecting group used in peptide synthesis to prevent unwanted reactions. Uses: Fmoc-5-hydroxy-dl-tryptophan has various applications in scientific experiments, such as peptide synthesis, structural biology, and drug discovery. fmoc-5-hydroxy-dl-tryptophan can be used as a building block to synthesize peptides and proteins with specific functions or properties. Group: Amino acids. Alternative Names: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-5-hydroxy-L-tryptophan. CAS No. 351857-99-3. Molecular formula: C26H22N2O5. Mole weight: 442.5. Purity: Peak Area by HPLC ≥95%. IUPACName: 2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid. Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)NC (CC4=CNC5=C4C=C (C=C5)O)C (=O)O. Density: 1.4±0.1 g/cm3. Catalog: ACM351857993. | |
| Fmoc-5-methoxy-L-tryptophan | Fmoc-5-methoxy-L-tryptophan is a derivative of tryptophan that contains a methoxy group at the 5-position of the indole ring and is protected with a 9-fluorenylmethoxy carbonyl (Fmoc) group at the amino terminus. Uses: Fmoc-5-methoxy-l-tryptophan has shown potential applications in various fields of research. it has been studied for its use in drug discovery, as a therapeutic agent for neurodegenerative diseases, and as an antioxidant and anti-inflammatory agent. Group: Amino acids. Alternative Names: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-methoxy-L-tryptoph. CAS No. 1219184-52-7. Molecular formula: C27H24N2O5. Mole weight: 456.5. Purity: Peak Area by HPLC ≥95%. IUPACName: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(5-methoxy-1H-indol-3-yl)propanoic acid. Canonical SMILES: COC1=CC2=C (C=C1)NC=C2CC (C (=O)O)NC (=O)OCC3C4=CC=CC=C4C5=CC=CC=C35. Catalog: ACM1219184527. | |
| Fmoc-6-Ahx-OH | Standard building block for introduction of aminohexanoic amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: 6-(Fmoc-amino)caproic acid, 6-(Fmoc-amino)hexanoic acid, Fmoc-ε-Ahx-OH, N-ε -Fmoc-ε -aminocaproic acid, Fmoc-6-aminohexanoic acid. CAS No. 88574-06-5. Molecular formula: C21H23NO4. Mole weight: 353.41. Canonical SMILES: OC(=O)CCCCCNC(=O)OCC1c2ccccc2-c3ccccc13. Catalog: ACM88574065. | |
| Fmoc-6-methyl-DL-tryptophan | Fmoc-6-methyl-DL-tryptophan is a synthetic amino acid derivative that is used as a building block for peptide synthesis. It is a derivative of tryptophan, an essential amino acid that is important for protein synthesis in humans. Fmoc-6-methyl-DL-tryptophan is characterized by the presence of an additional methyl group at the 6-position of the indole ring. Uses: Fmoc-6-methyl-dl-tryptophan has a wide range of applications in scientific experiments, including the synthesis of novel peptides and peptidomimetics, the design of new therapeutic agents, and the study of the function and structure of proteins. Group: Amino acids. Alternative Names: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-6-methyltryptophan. CAS No. 1219150-44-3. Molecular formula: C27H24N2O4. Mole weight: 440.5. Purity: Peak Area by HPLC ≥95%. IUPACName: 2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(6-methyl-1H-indol-3-yl)propanoic acid. Canonical SMILES: CC1=CC2=C (C=C1)C (=CN2)CC (C (=O)O)NC (=O)OCC3C4=CC=CC=C4C5=CC=CC=C35. Density: 1.3±0.1 g/cm3. Catalog: ACM1219150443. | |
| Fmoc-7-methyl-DL-tryptophan | Fmoc-7-methyl-DL-tryptophan is a derivative of tryptophan, a common amino acid found in proteins. The term 'Fmoc' stands for fluoren-9-ylmethoxycarbonyl, which is a protective group that is commonly used in peptide synthesis. Fmoc-7-methyl-DL-tryptophan is a white crystalline powder that is soluble in organic solvents such as dimethylformamide and dimethyl sulfoxide. Uses: Fmoc-7-methyl-dl-tryptophan has a wide range of applications in various scientific experiments. it is commonly used in peptide synthesis and as a building block for the synthesis of various bioactive peptides. the compound is also used in drug discovery and development, as well as in the study of protein-protein interactions. Group: Amino acids. Alternative Names: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-7-methyltryptophan. CAS No. 138775-53-8. Molecular formula: C27H24N2O4. Mole weight: 440.5. Purity: Peak Area by HPLC ≥95%. IUPACName: 2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(7-methyl-1H-indol-3-yl)propanoic acid. Canonical SMILES: CC1=C2C (=CC=C1)C (=CN2)CC (C (=O)O)NC (=O)OCC3C4=CC=CC=C4C5=CC=CC=C35. Density: 1.3±0.1 g/cm3. Catalog: ACM138775538. | |
| Fmoc-ACA-OH | Fmoc-ACA-OH is a useful tool for the SPPS of AMC fluorogenic protease substrates by Fmoc SPPS. Fmoc-ACA-OH must be first loaded onto a Wang-type resin. Any unreacted linker hydroxyls must be capped using acetic anhydride. Following Fmoc removal, the first amino acid should be coupled with HATU/collidine. Insertion of ACA into the middle of a peptide provides fluorogenic substrates for endopeptidases. Treatment of the ACC peptide obtained after TFA cleavage with an aqueous base causes facile decarboxylation and formation of the AMC peptide. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-ACA-OH, 7-N-Fmoc-aminocoumarin-4-acetic acid. CAS No. 378247-75-7. Mole weight: 441.43. Catalog: ACM378247757. | |
| Fmoc-Aib-OH | Standard building block for introduction of aminoisobutyric amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Aib-OH, N-α -Fmoc-α -aminoisobutyric acid, N-Fmoc-C-α-methylalanine, Fmoc-alpha-aminoisobutyric acid. CAS No. 94744-50-0. Molecular formula: C19H19NO4. Mole weight: 325.36. Catalog: ACM94744500. | |
| Fmoc-Ala-OH | High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of alanine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Ala-OH, N-α-Fmoc-L-alanine monohydrate. CAS No. 35661-39-3. Molecular formula: C18H17NO4. Mole weight: 311.33. Catalog: ACM35661393. | |
| Fmoc-alpha-methyl-DL-glutamic acid | Fmoc-alpha-methyl-DL-glutamic acid is an Fmoc protected derivative of glutamic acid. Uses: Peptide synthesis. Group: Amino acids. CAS No. 1219372-49-2. Molecular formula: C21H21NO6. Mole weight: 383.4. Purity: Peak Area by HPLC ≥95%. Canonical SMILES: CC (CCC (=O)O) (C (=O)O)NC (=O)OCC1c2ccccc2-c3c1cccc3. Catalog: ACM1219372492. | |
| Fmoc-alpha-methyl-DL-methionine | Fmoc-α-methyl-DL-methionine is a derivative of methionine, an essential amino acid that cannot be synthesized by the human body and must be obtained from dietary sources. Methionine is involved in various biological functions such as protein synthesis, methylation, and sulfur metabolism. Fmoc-α-methyl-DL-methionine is a modified form of methionine, where the alpha carbon is replaced with a methyl group and the amino group is protected with a Fmoc (9-fluorenylmethoxycarbonyl) group. The Fmoc group can be removed under mildly basic conditions, allowing for the synthesis of peptides and proteins containing Fmoc-α-methyl-DL-methionine. Uses: Fmoc-α-methyl-dl-methionine has been used in peptide and protein synthesis, where it can be incorporated as a unique building block to modulate protein structure and function. it has also been used in the development of novel biomaterials. Group: Amino acids. CAS No. 147108-43-8. Molecular formula: C21H23NO4S. Mole weight: 385.5. IUPACName: 2-(9H-fluoren-9-ylmethoxycarbonylamino)-2-methyl-4-methylsulfanylbutanoic acid. Canonical SMILES: CC (CCSC) (C (=O)O)NC (=O)OCC1C2=CC=CC=C2C3=CC=CC=C13. Density: 1.3±0.1 g/cm3. Catalog: ACM147108438. | |
| Fmoc-α-t-butylglycine | Standard building block for introduction of t-butylglycine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-α-t-butylglycine, N-α-Fmoc-L-α-t.-butyl-glycine, Fmoc-Tle-OH. CAS No. 132684-60-7. Molecular formula: C21H23NO4. Mole weight: 353.41. Catalog: ACM132684607. | |
| Fmoc-Arg(Pbf)-OH | High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. The standard derivative for the introduction of Arg in Fmoc SPPS. The Pbf side-chain protecting group is removed with TFA approximately 1-2 times faster than Pmc.In the preparation of peptides containing both Arg and Trp, it is recommended that this derivative is used in conjunction with Fmoc-Trp(Boc)-OH. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Arg(Pbf)-OH, N-α-Fmoc-N G-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine. CAS No. 154445-77-9. Molecular formula: C34H40N4O7S. Mole weight: 648.77. Appearance: White to off-white solid. Purity: 0.98. IUPACName: (2S) -5-[[amino-[ (2, 2, 4, 6, 7-pentamethyl-3H-1-benzofuran-5-yl) sulfonylamino]methylidene]amino]-2- (9H-fluoren-9-ylmethoxycarbonylamino) pentanoic acid. Canonical SMILES: CC1=C (C (=C (C2=C1OC (C2) (C)C)C)S (=O) (=O)NC (=NCCC[C@@H] (C (=O)O)NC (=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)N)C. Density: 1.37±0.1 g/ml. Catalog: ACM154445779-1. | |
| Fmoc-Arg(Pmc)-OH | An excellent derivative for the introduction of Arg in Fmoc SPPS. The Pmc group is removed by TFA in 1-3 hours. In the synthesis of peptides containing both Arg and Trp, it is recommended that this derivative is used in conjunction with Fmoc-Trp(Boc)-OH. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Arg(Pmc)-OH, N-α-Fmoc-N G-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-L-arginine. CAS No. 119831-72-0. Mole weight: 662.8. Catalog: ACM119831720. | |
| Fmoc-Asn(Dmcp)-OH | A superior derivative to Fmoc-Asn(Trt)-OH for the synthesis of Asn-containing peptides by Fmoc SPPS. Fmoc-Asn(Dmcp)-OH is more soluble in DMF than Fmoc-Asn(Trt)-OH, thereby facilitating coupling reactions at higher concentration. Cleavage of the Dmcp group is rapid, even when the residue is located at the N-terminus of a peptide. Coupling of Dmcp-protected derivatives is faster than that of the corresponding hindered Trt derivatives. Dmcp-protected peptides have enhanced solubility. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Asn(Dmcp)-OH, N-α-Fmoc-N-β-(1-cyclopropyl-1-methylethyl)-L-asparagine. CAS No. 172947-19-2. Mole weight: 436.5. Catalog: ACM172947192. | |
| Fmoc-Asn-OH | Building block for introduction of asparagine by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Asn-OH, N-α-Fmoc-L-asparagine. CAS No. 71989-16-7. Mole weight: 354.36. Catalog: ACM71989167. | |
| FMOC-Asn(Trt)-OH | High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Fmoc-Asn(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Asn. Coupling can be performed by standard procedures. The trityl group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp residues. When Asn(Trt) is the N-terminal residue, the reaction time may need to be extended to ensure complete deprotection. Literature references P. Sieber, et al. in 'Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium', R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 577. P. Sieber, et al. (1991) Tetrahedron Lett., 32, 739. M. Friede, et al. (1992) Pept. Res., 5, 145. Uses: Fmoc-asn(trt)-oh has diverse applications in scientific experiments. it is commonly used in peptide synthesis, where it is used as a building block to assemble longer peptides. other applications include generating specific peptide sequences for biological studies, designing new drugs, and studying protein interactions. Group: Amino acids. Alternative Names: FMOC-Asn(Trt)-OH, N-α-Fmoc-N-β-trityl-L-asparagine. CAS No. 132388-59-1. Molecular formula: C38H32N2O5. Mole weight: 596.67. Canonical SMILES: C1=CC=C (C= | |
| Fmoc-Asp-OAll | Orthogonally-protected building block for the synthesis of head-to-tail cyclic peptides by Fmoc SPPS. The α-allyl ester can be selectively removed in the presence of Fmoc- and tBu-based protecting groups by treatment with Pd(Ph3P)4/ CHCl3/AcOH/NMM , thereby facilitating the synthesis of branched esters, amides, lactones and lactams incorporating an aspartyl unit. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Asp-OAll, N-α-Fmoc-L-aspartic acid α-allyl ester. CAS No. 144120-53-6. Molecular formula: C22H21NO6. Mole weight: 395.41. Catalog: ACM144120536. | |
| Fmoc-Asp(OAll)-OH | Orthogonally-protected building block for the synthesis of peptides modified at the Asp side chain by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Asp(OAll)-OH. CAS No. 146982-24-3. Mole weight: 395.41. Catalog: ACM146982243. | |
| Fmoc-Asp(OBzl)-OH | High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Asp(OBzl)-OH, N-α-Fmoc-L-aspartic acid β-benzyl ester. CAS No. 86060-84-6. Mole weight: 445.46. Catalog: ACM86060846. | |
| Fmoc-Asp-OtBu | Selectively protected building block for library synthesis or the preparation of β-aspartyl peptides by Fmoc SPPS. After condensation of the side-chain carboxy with an appropriate amine or alcohol, the β-amino and carboxy functions can be selectively unmasked with 20% piperidine in DMF and 50% TFA in DCM respectively, facilitating the synthesis of branched esters and amides, and lactams and lactones containing the aspartyl unit. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Asp-OtBu, N-α-Fmoc-L-aspartic acid α-t.-butyl ester. CAS No. 129460-09-9. Molecular formula: C23H25NO6. Mole weight: 411.45. Catalog: ACM129460099. | |
| Fmoc-Asp(OtBu)-(Dmb)Gly-OH | Fmoc-Aaa-(Dmb)Gly-OH dipeptides offer the same benefits as pseudoproline dipeptides in Fmoc SPPS but for peptide sequences containing Gly. They are extremely easy to use. Standard coupling methods like PyBOP/DIPEA or DIPCDI/HOBt can be used for their introduction. Removal of the Dmb group and regeneration of the glycine residue occurs during the course of standard TFA-mediated cleavage reaction. This derivative also completely inhibits aspartimide formation. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Asp(OtBu)-(Dmb)Gly-OH, N-α-Fmoc-β-O-t.-butyl-L-aspartyl-N-α-(2,4-dimethoxybenzyl)-glycine. CAS No. 900152-72-9. Mole weight: 618.67. Catalog: ACM900152729. | |
| Fmoc-Asp(OtBu)-OH (U-13 C4, 15N) | Fmoc-Asp(OtBu)-OH-13C4,15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is an aspartate derivative containing amine-protecting group Fmoc. Uses: Fmoc-asp(otbu)-oh can be used for peptide synthesis. Group: Amino acids. CAS No. 1160760-08-6. Molecular formula: (CH3) 3COO13< / sup>C13< / sup>CH213< / sup>CH (15< / sup>NH-Fmoc) 13< / sup>COOH. Mole weight: 416.4. Purity: Peak Area by HPLC ≥95%. Canonical SMILES: CC (C) (C)O[13C] (=O)[13CH2][13C@@H] ([13C] (=O)O)[15NH]C (=O)OCC1C2=CC=CC=C2C3=CC=CC=C13. Catalog: ACM1160760086. | |
| Fmoc-Asp(OtBu)-Ser(psiMe,Mepro)-OH | This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Asp-Ser dipeptide motif. It consists of a dipeptide in which the serine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The serine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Asp(OtBu)-Ser(psiMe,Mepro)-OH. CAS No. 955048-92-7. Mole weight: 538.59. Catalog: ACM955048927. | |
| Fmoc-azidolysine | A useful tool for the synthesis of branched, side-chain modified and cyclic peptides and peptide tools for click chemistry by Fmoc SPPS. The side-chain azido group is completely stable to piperidine and TFA, but can be readily converted to an amine on the solid phase or in solution by reduction with thiols or phosphines. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-azidolysine. CAS No. 159610-89-6. Molecular formula: C21H22N4O4. Mole weight: 394.42. Catalog: ACM159610896. | |
| Fmoc-beta-(2-pyridyl)-L-alanine | Fmoc-?-(2-pyridyl)-Ala-OH is an Fmoc protected alanine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Alanine is one of the simplest amino acids - a methyl group as the side chain. This small side chain confers a high degree of flexibility (second only to glycine) when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group. Uses: Fmoc-β-(2-pyridyl)-ala-oh is an fmoc protected alanine derivative. Group: Amino acids. Alternative Names: Fmoc-3-(2-pyridyl)-L-alanine. CAS No. 185379-40-2. Molecular formula: C23H20N2O4. Mole weight: 388.4. Canonical SMILES: OC (=O)[C@H] (Cc1ccccn1)NC (=O)OCC2c3ccccc3-c4ccccc24. Density: 1.3±0.1 g/cm3. Catalog: ACM185379402. | |
| Fmoc-β-HomoArg(Pbf)-OH | Fmoc-homoArg(Pbf)-OH is a useful tool for the introduction of homoarginine during Fmoc SPPS. It can be used in exactly the same manner as Fmoc-Arg(Pbf)-OH. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: N-α-Fmoc-NG-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-homoarginine. CAS No. 401915-53-5. Molecular formula: C35H42N4O7S. Mole weight: 662.8. Purity: ≥ 97 % (TLC(157B)). IUPACName: (2S) -6-[[amino-[ (2, 2, 4, 6, 7-pentamethyl-3H-1-benzofuran-5-yl) sulfonylamino]methylidene]amino]-2- (9H-fluoren-9-ylmethoxycarbonylamino) hexanoic acid. Canonical SMILES: CC1=C (C (=C (C2=C1OC (C2) (C)C)C)S (=O) (=O)NC (=NCCCCC (C (=O)O)NC (=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)N)C. Density: 1.4±0.1 g/cm3. Catalog: ACM401915535. | |
| Fmoc-beta-methyl-DL-phenylalanine | FMOC-beta-Me-DL-Phe is a derivative of the amino acid phenylalanine, which is an essential amino acid that cannot be synthesized by the human body and must be obtained through the diet. FMOC-beta-Me-DL-Phe is a modified version of phenylalanine that is used in peptide synthesis for its ability to protect the amino group during chemical reactions. Uses: Fmoc-beta-me-dl-phe is commonly used in peptide synthesis for its ability to protect the amino group. it has also been used in the development of antimicrobial and anticancer agents. Group: Amino acids. CAS No. 1214028-21-3. Molecular formula: C25H23NO4. Mole weight: 401.5. Purity: Peak Area by HPLC ≥95%. IUPACName: 2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylbutanoic acid. Canonical SMILES: CC (C1=CC=CC=C1)C (C (=O)O)NC (=O)OCC2C3=CC=CC=C3C4=CC=CC=C24. Catalog: ACM1214028213. | |
| Fmoc-Bpa-OH | Fmoc-p-Bz-Phe-OH is a useful tool for preparing photoactivatable peptide-based affinity probes. On photolysis at 366 nm, Benzoylphenylalanine (Bpa) generates a biradical that has a preference for insertion into C-H bonds, particularly those of Leu, Val and Met side chains. The derivative can be introduced using standard coupling method such as PyBOP and is stable to conditions used in peptide chain extension. For the cleavage of Bpa containing peptide from the resin, the use of thiols and silanes should be avoided as dithioketal formation and reduction, respectively, have been observed. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-4-benzoyl-L-phenylalanine. CAS No. 117666-96-3. Molecular formula: C31H25NO5. Mole weight: 491.53. Canonical SMILES: OC (=O)[C@H] (Cc1ccc (cc1)C (=O)c2ccccc2)NC (=O)OCC3c4ccccc4-c5ccccc35. Catalog: ACM117666963. | |
| Fmoc-Cha-OH | Standard building block for introduction of cyclohexylalanine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Cha-OH, N-α-Fmoc-β-cyclohexyl-L-alanine. CAS No. 135673-97-1. Mole weight: 393.48. Catalog: ACM135673971. | |
| Fmoc-Cit-OH | Standard building block for introduction of citrulline amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Cit-OH, N-α-Fmoc-L-2-amino-5-ureido-n-valeric acid, Fmoc-L-citrulline. CAS No. 133174-15-9. Molecular formula: C21H23N3O5. Mole weight: 397.42. Catalog: ACM133174159. | |
| Fmoc-Cys(Acm)-OH | The side-chain Acm group is stable to TFA but can be removed with Hg(II) or Ag(I) to give cysteinyl peptides, or oxidatively with Tl(III) or I2 to generate cystinyl peptides. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Cys(Acm)-OH, N-α-Fmoc-S-acetamidomethyl-L-cysteine. CAS No. 86060-81-3. Mole weight: 414.47. Catalog: ACM86060813. | |
| Fmoc-Cys(Dpm)-OH | The Dpm group has increased stability compared to Trt, enabling selective removal of Mtt groups on the solid phase with dilute TFA without loss of Dpm groups. Furthermore, the Dpm group is removed by treatment with 95% TFA cleavage cocktails. Racemization during carboxyl activation is lower with this derivative than with Fmoc-Cys(Trt)-OH. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Cys(Dpm)-OH, N-α-Fmoc-S-diphenylmethyl-L-cysteine. CAS No. 247595-29-5. Mole weight: 509.62. Catalog: ACM247595295. | |
| Fmoc-Cys(Mmt)-OH | Building block for Fmoc SPPS which enables selective deprotection of cysteinyl thiol group on the solid phase. The Mmt group can be removed on the solid phase with 1% TFA in DCM containing 5% TIS. Reference 4 describes a novel method for on-resin disulfide bond formation which uses Cys(Mmt) in combination with Cys(tBuS). Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Cys(Mmt)-OH, N-α-Fmoc-S-p-methoxytrityl-L-cysteine. CAS No. 177582-21-7. Molecular formula: C38H33NO5S. Mole weight: 615.74. Catalog: ACM177582217. | |
| (Fmoc-cys-osu)2 | Heterocyclic Organic Compound. CAS No. 112514-60-0. Molecular formula: C44H38N4O12S2. Mole weight: 878.94. Catalog: ACM112514600. | |
| Fmoc-Cys(STmp)-OH | Fmoc-Cys(STmp)-OH is a novel new tool for the regioselective synthesis of multiple disulfide bridged peptides by Fmoc SPPS. The STmp group is stable to piperidine but is extremely easy to remove by mild thiolysis. Albericio has reported removing four STmp groups on the solid phase with only three 5 minute treatments of 0.1 M N-methylmorpholine (NMM) in DMF containing 5% DTT. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Cys(STmp)-OH, N-α-Fmoc-S-2,4,6-trimethoxyphenylthio-L-cysteine. CAS No. 1403834-74-1. Molecular formula: C27H27NO7S2. Mole weight: 541.64. IUPACName: (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[(2,4,6-trimethoxyphenyl)disulfanyl]propanoic acid. Canonical SMILES: COC1=CC (=C (C (=C1)OC)SSCC (C (=O)O)NC (=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)OC. Density: 1.4±0.1 g/cm3. Catalog: ACM1403834741. | |
| Fmoc-Cys(tBu)-OH | The side-chain tBu group is stable to TFA and iodine oxidation. Treatment with MeSiCl3/PhSOPh removes t-Bu and cyclizes in one step without scrambling existing disulphide bonds. Removed with Hg(II) to give cysteinyl peptides. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Cys(tBu)-OH, N-α-Fmoc-S-t.-butyl-L-cysteine. CAS No. 67436-13-9. Mole weight: 399.5. Catalog: ACM67436139. | |
| Fmoc-Cys(THP)-OH | Fmoc-Cys(Thp)-OH is a new building block for Fmoc SPPS, in which the sulfhydryl group is protected with the acid-cleavable tetrahydropyranyl (Thp) group. The use of Fmoc-Cys(Thp)-OH has been shown to give superior results to the corresponding S-Trt, S-Dpm, S-Acm, and S-StBu derivatives. Uses: The identification and purity of fmoc-l-cys(thp)-oh can be determined through various analytical methods, including nuclear magnetic resonance (nmr) spectroscopy, high-resolution mass spectrometry (hr-ms), and hplc. these methods provide information on the molecular structure, molecular weight, and purity of the compound. Group: Amino acids. Alternative Names: Fmoc-Cys(THP)-OH, N-α-Fmoc-S-(tetrahydropyranyl)-L-cysteine. CAS No. 1673576-83-4. Molecular formula: C23H25NO5S. Mole weight: 427.51. IUPACName: (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(oxan-2-ylsulfanyl)propanoic acid. Canonical SMILES: C1CCOC (C1)SCC (C (=O)O)NC (=O)OCC2C3=CC=CC=C3C4=CC=CC=C24. Catalog: ACM1673576834. | |
| Fmoc-Cys(Trt)-OH | High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. The standard derivative for Fmoc SPPS of peptides containing Cys. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP, is to be employed, it is strongly recommended that collidine is used as the base , as this has been shown to significantly reduce loss of optical integrity during coupling. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Cys(Trt)-OH, N-α-Fmoc-S-trityl-L-cysteine. CAS No. 103213-32-7. Molecular formula: C37H31NO4S. Mole weight: 585.71. Catalog: ACM103213327-1. | |
| Fmoc-Dab(ivDde)-OH | This orthogonally-protected diaminobutyric acid derivative is based on the hindered Dde variant ivDde. The side-chain ivDde group is considerably more stable to piperidine than Dde and is less prone to migrate from protected to unprotected side-chains and from side-chain to γ-amino group.When removing ivDde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Dab(ivDde)-OH, N-α-Fmoc-N-γ-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-diaminobutanoic acid. CAS No. 607366-21-2. Mole weight: 546.65. Catalog: ACM607366212. | |
| Fmoc-D-Ala-OH | Standard building block of introduction of D-alanine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Ala-OH, N-α-Fmoc-D-alanine. CAS No. 79990-15-1. Molecular formula: C18H17NO4. Mole weight: 311.33. Catalog: ACM79990151. | |
| Fmoc-D-α-t-butylglycine | Standard building block of introduction of D-t-butylglycine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-α-t-butylglycine, N-α-Fmoc-D-α-t.-butyl-glycine, N-α-Fmoc-D-t-leucine. CAS No. 198543-64-5. Mole weight: 353.41. Catalog: ACM198543645. | |
| Fmoc-D-Arg(Pbf)-OH | Standard building block of introduction of D-arginine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Arg(Pbf)-OH, N-α-Fmoc-N G-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-D-arginine. CAS No. 187618-60-6. Molecular formula: C34H40N4O7S. Mole weight: 648.77. Catalog: ACM187618606. | |
| Fmoc-D-Asn-OH | Standard building block of introduction of D-asparagine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Asn-OH, N-α-Fmoc-D-asparagine. CAS No. 108321-39-7. Mole weight: 354.36. Catalog: ACM108321397. | |
| Fmoc-D-Asn(Trt)-OH | Standard building block of introduction of D-asparagine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-N-trityl-D-asparagine. CAS No. 180570-71-2. Molecular formula: C38H32N2O5. Mole weight: 596.67. Canonical SMILES: OC (=O)[C@@H] (CC (=O)NC (c1ccccc1) (c2ccccc2)c3ccccc3)NC (=O)OCC4c5ccccc5-c6ccccc46. Catalog: ACM180570712. | |
| Fmoc-D-Asp-OtBu | Standard building block of introduction of D-aspartic acid amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Asp-OtBu, N-α-Fmoc-D-aspartic acid α-t.-butyl ester. CAS No. 134098-70-7. Mole weight: 411.45. Catalog: ACM134098707. | |
| Fmoc-D-asp(otbu)-oh | Heterocyclic Organic Compound. CAS No. 112883-39-3. Molecular formula: C23H25NO6. Mole weight: 411.45. Catalog: ACM112883393. | |
| Fmoc-D-Cha-OH | Standard building block of introduction of D-cyclohexyl amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Cha-OH, N-α-Fmoc-β-cyclohexyl-D-alanine. CAS No. 144701-25-7. Mole weight: 393.48. Catalog: ACM144701257. | |
| Fmoc-D-Cys(Trt)-OH | Standard building block of introduction of D-cysteine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Nα-Fmoc-S-trityl-D-cysteine. CAS No. 167015-11-4. Molecular formula: C37H31NO4S. Mole weight: 585.71. Canonical SMILES: OC (=O)[C@@H] (CSC (c1ccccc1) (c2ccccc2)c3ccccc3)NC (=O)OCC4c5ccccc5-c6ccccc46. Catalog: ACM167015114. | |
| Fmoc-D-gla(otbu)2-oh | Heterocyclic Organic Compound. CAS No. 111662-65-8. Molecular formula: C29H35NO8. Mole weight: 525.6. Catalog: ACM111662658. | |
| Fmoc-D-Gln(Trt)-OH | Standard building block of introduction of D-glutamine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-N-trityl-D-glutamine. CAS No. 200623-62-7. Molecular formula: C39H34N2O5. Mole weight: 610.7. Canonical SMILES: OC (=O)[C@@H] (CCC (=O)NC (c1ccccc1) (c2ccccc2)c3ccccc3)NC (=O)OCC4c5ccccc5-c6ccccc46. Catalog: ACM200623627. | |
| Fmoc-D-Glu-ODmab | Fmoc-D-Glu-ODmab is a glycine-extended peptide that is used as a resin-bound peptide for solid-phase peptide synthesis. The D-glutamic acid residue has a higher chemical stability compared to L-glutamic acid, which makes it a suitable component for peptide synthesis. The Fmoc group serves as a protecting group for the amino group, which is removed during the peptide elongation process. The ODmab group serves as a C-terminal protecting group that can be removed using mild acidic conditions. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Glu-ODmab, N-α-Fmoc-D-glutamic acid α-4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-amino} benzyl ester. CAS No. 874486-65-4. Molecular formula: C40H44N2O8. Mole weight: 680.79. IUPACName: (4R) -4- (9H-fluoren-9-ylmethoxycarbonylamino) -5- [ [4- [ [1- (2-hydroxy-4, 4-dimethyl-6-oxocyclohexen-1-yl) -3-methylbutylidene] amino] phenyl] methoxy] -5-oxopentanoic acid. Canonical SMILES: CC (C)CC (=NC1=CC=C (C=C1)COC (=O)C (CCC (=O)O)NC (=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C5=C (CC (CC5=O) (C)C)O. Catalog: ACM874486654. | |
| Fmoc-D-Glu(OtBu)-OH | Standard building block of introduction of D-glutamic acid amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-glutamic acid 5-tert-butyl ester. CAS No. 104091-08-9. Molecular formula: C24H27NO6. Mole weight: 425.47. Canonical SMILES: CC (C) (C)OC (=O)CC[C@@H] (NC (=O)OCC1c2ccccc2-c3ccccc13)C (O)=O. Catalog: ACM104091089. | |
| Fmoc-D-glutamine | Heterocyclic Organic Compound. CAS No. 112898-00-7. Molecular formula: C20H20N2O5. Mole weight: 368.38. Catalog: ACM112898007. | |
| Fmoc-D-His(Clt)-OH | Building block for introduction of D-histidine by Fmoc SPPS. The Clt group is more stable to acid than Trt and its use avoids the formation of partially protected histidine peptides during the preparation of protected fragments. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-His(Clt)-OH, N-α-Fmoc-N-im-2-chlorotrityl-D-histidine. CAS No. 1272755-56-2. Molecular formula: C40H32ClN3O4. Mole weight: 654.15. IUPACName: (2R)-3-[1-[(2-chlorophenyl)-diphenylmethyl]imidazol-4-yl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid. Canonical SMILES: C1=CC=C (C=C1)C (C2=CC=CC=C2) (C3=CC=CC=C3Cl)N4C=C (N=C4)CC (C (=O)O)NC (=O)OCC5C6=CC=CC=C6C7=CC=CC=C57. Catalog: ACM1272755562. | |
| Fmoc-D-His(Trt)-OH | Standard building block of introduction of D-histidine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-N(im)-trityl-D-histidine. CAS No. 135610-90-1. Molecular formula: C40H33N3O4. Mole weight: 619.71. Canonical SMILES: OC (=O)[C@@H] (Cc1cn (cn1)C (c2ccccc2) (c3ccccc3)c4ccccc4)NC (=O)OCC5c6ccccc6-c7ccccc57. Catalog: ACM135610901. | |
| Fmoc-D-Ile-OH | Standard building block for introduction of D-isoleucine by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Ile-OH, N-α-Fmoc-D-Isoleucine. CAS No. 143688-83-9. Mole weight: 353.41. Catalog: ACM143688839. | |
| Fmoc-D-Leu-OH | Standard building block of introduction of D-leucine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Leu-OH, N-α-Fmoc-D-leucine. CAS No. 114360-54-2. Molecular formula: C21H23NO4. Mole weight: 353.41. Catalog: ACM114360542. | |
| Fmoc-D-Lys(Boc)-OH | Standard building block of introduction of D-lysine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Nα-Fmoc-N-ε-Boc-D-lysine. CAS No. 92122-45-7. Molecular formula: C26H32N2O6. Mole weight: 468.54. Canonical SMILES: CC (C) (C)OC (=O)NCCCC[C@@H] (NC (=O)OCC1c2ccccc2-c3ccccc13)C (O)=O. Catalog: ACM92122457. | |
| Fmoc-D-Lys(ivDde)-OH | This orthogonally-protected lysine derivative is based on the hindered Dde variant ivDde. It has very similar chemical properties to Fmoc-Lys(Dde)-OH, except that the side-chain ivDde group is considerably more stable to piperidine than Dde, and is less prone to migrate from protected to unprotected lysine side-chains. When removing ivDde in the presence of allyl based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Lys(ivDde)-OH, N-α-Fmoc-N-ε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3methylbutyl-D-lysine. CAS No. 1272755-33-5. Molecular formula: C34H42N2O6. Mole weight: 574.71. Density: 1.2±0.1 g/cm3. Catalog: ACM1272755335. | |
| Fmoc-D-lys-oh | Heterocyclic Organic Compound. Alternative Names: N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-LYSINE;FMOC-D-LYSINE;FMOC-D-LYS-OH. CAS No. 110990-08-4. Molecular formula: C21H24N2O4. Mole weight: 368.43. Catalog: ACM110990084. | |
| Fmoc-(Dmb)Gly-OH | Fmoc-(Dmb)Gly-OH is an excellent reagent for enhancing synthetic efficiency of glycine-containing peptides by Fmoc SPPS.Like the analogous Hmb derivative Fmoc-(FmocHmb)Gly-OH, the use of this derivative prevents aggregation during chain assemby, thereby leading to faster and more predictable acylation and deprotection reactions. Furthermore, it can prevent aspartimide formation when used to introduce a Gly immediately before an Asp residue and help promote cyclization of Gly-containing peptides. The analogous (Tmob)Gly derivative has been used by Bayer and colleagues to prepare a 64-residue transmembrane peptide in remarkable purity. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-(Dmb)Gly-OH, N-α-Fmoc-N-α-(2, 4-dimethoxybenzyl)-glycine. CAS No. 166881-42-1. Mole weight: 447.48. Catalog: ACM166881421. | |
| Fmoc-D-Met-OH | Standard building block of introduction of D-methionine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Met-OH, N-α-Fmoc-D-methionine. CAS No. 112883-40-6. Mole weight: 371.45. Catalog: ACM112883406. | |
| Fmoc-D-Nle-OH | Standard building block of introduction of D-norleucine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Nle-OH, N-α-Fmoc-D-norleucine. CAS No. 112883-41-7. Mole weight: 353.41. Catalog: ACM112883417. | |
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